Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PCNA EEF1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
H2AX SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
H2AX DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
H2AX ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19146767 11673449
ATM H2AX â—¼   COLOCALIZATION 2.0 0.8 intact 16858402 5218840
H2AX NHEJ1 â—¼   COLOCALIZATION 2.0 0.8 intact 6175821 18064046
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
DCLRE1C XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16857680
PAXX XRCC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1261971 25574025
RPL23A AHNAK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDCD4 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
SUMO2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
TP53BP1 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
EEF1A1 NEU1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NEBL LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LMNA PDCD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MRFAP1 PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NHEJ1 XRCC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PRPS1 SPRY4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPS1 TDG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SDC4 SDC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
SDC2 SDC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
SUMO2 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
TERF2 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21824286 8202878
NHEJ1 ESPN â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
NHEJ1 C1D â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
ATM CRIPT â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
NHEJ1 APOE â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
NHEJ1 SPRY4 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
XRCC4 DEF6 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
XRCC4 TERF2 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
XRCC4 JADE2 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
NHEJ1 MAVS â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
NHEJ1 NRK â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
ATM CNN1 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
XRCC4 NDUFA4 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
NHEJ1 P3H4 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
NHEJ1 DIAPH2 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
XRCC4 DIDO1 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
NHEJ1 PRAF2 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
NHEJ1 ZNF589 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
NHEJ1 SLC2A13 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
NHEJ1 TMEM263 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
CD81 APOE â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
DCLRE1C PRKAB2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ATM TSPYL1 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
NHEJ1 TIMM13 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
NHEJ1 PRPS1 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
ATM HSPG2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
NHEJ1 STAP2 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
NHEJ1 IMUP â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
NHEJ1 SERF2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
PAXX PYGL â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
NHEJ1 GALNT17 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
XRCC4 GNG7 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
H2AX LMNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25948554 20000738 23658700
H2AX XRCC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20085707 21679440 18406329
XRCC6 DNLI4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22990118 15520013 10757784 26496610
H2AFY2 EPS8L2 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
NHEJ1 LONP2 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
COX6A1 NDUFA4 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
VPS11 VPS33A â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
XRCC4 SDHA â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
NHEJ1 SUMO2 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
NHEJ1 SAT2 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
NHEJ1 RPL23A â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
NHEJ1 USP24 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
CDC6 FBXW7 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
NHEJ1 ATR â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
TDG MRFAP1 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
NHEJ1 UPP1 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
NHEJ1 GSTZ1 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
NHEJ1 RBM46 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
LMNA PCNA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24623722 29753763 30419336
PCNA XRCC6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11239001 24695737 12171929
FGF2 SDC4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 16982797
XRCC4 PHYH â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
NHEJ1 FADS2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
VPS11 VPS18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
EEF1A1 RPS27A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
NHEJ1 TRMT61A â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
RPS27A TP53BP1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
VPS18 VPS33A â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ATM EML2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
H2AX XRCC6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15613478 33961781 23145133 20224553 28514442 18406329
XRCC4 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9430729 15194694 22939629 9259561 15520013
LMNA IFFO1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24623722 31548606
NHEJ1 MRPL33 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
ATM PHYH â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
TDG CAVIN1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
NHEJ1 PCCB â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
NHEJ1 C1orf52 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
PAXX TWSG1 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
H2AX PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15613478 26095369 14627815 18406329 22184063 20085707 20356835
ATM PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10464290 10608806
XRCC4 NUFIP1 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
NHEJ1 PAIP2 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
NHEJ1 H1FX â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
COX6C NDUFA4 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
NHEJ1 TDG â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
XRCC4 MARCKS â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
NHEJ1 ZMYND11 â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
XRCC4 PDZD4 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
NHEJ1 RPS27A â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
ATR TP53BP1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
EEF1A1 RPL23A â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
TERF2 H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21044950 22157895 21824286
ATM H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18344987 26095369 21704408 22451927 11893489 20081839 16858402 9488723 22184063 11571274 21676867 32518374 27918549
CNN1 TPM1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 2161834 2455687
NHEJ1 PTGR2 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
NHEJ1 MRC2 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
NHEJ1 VARS2 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
PRKDC XRCC4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
NHEJ1 ANXA3 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
LIG4 XRCC6 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
XRCC4 CLYBL â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
NHEJ1 FLOT1 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
LIG4 NHEJ1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PCCA PCCB â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
NHEJ1 NCOA4 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
PCNA TP53BP1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DCLRE1C PRKDC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
XRCC4 PCCA â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
TERF2 XRCC6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
NHEJ1 PANK4 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
NHEJ1 CNN2 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
PRKDC DNLI4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22529269 10608806 15194694
FGF2 SDC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 16982797
NHEJ1 EPS8L2 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
NHEJ1 CDC42EP1 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
NHEJ1 TPRN â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
NHEJ1 ALDH6A1 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
NHEJ1 EIF4A2 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
NHEJ1 EEF1A1 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
XRCC4 ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
VPS41 VPS11 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 26463206 28514442 28931724 33422265
XRCC6 TERF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10984620 26496610 21044950
NHEJ1 QPCTL â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
ATM IMUP â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
XRCC4 HSPG2 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
NHEJ1 SLC30A1 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
TP53BP1 PPDPF â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
IFFO1 XRCC4 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NHEJ1 PFDN6 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
NSA2 RPL23A â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
NHEJ1 GPC6 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
NHEJ1 TSPYL1 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
NHEJ1 NUDCD1 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
XRCC4 DNLI4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 11702069 15520013 22658747 10757784 9705934 10854421 11809878 21070942 32296183 31548606 23219551 17567543 28514442 25416956 30496552 22529269 15194694 25910212 9259561 26186194
PCCB PCCA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 26344197 20725044 28514442 11749052
NIPSNAP1 DBI â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NHEJ1 DNLI4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 22658747 17567543 16439205
ALAS1 SUMO2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EEF1E1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15680327 18066086
EEF1E1 ATR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15680327 18066086
DDX5 SUMO2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25218447 17369852 25114211
EIF1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
XRCC5 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26496610 22404984 15520013 21679440 26446488 26344197 17308091 15941674 28154079 16857680 20711232 19303849 20023628 15758953 20085707 10750018 10446239 33005030 9312071 28345663 12393188
XRCC6 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8422676 20711232 19303849 26175416 28345663 30585729 17308091 22939629 26496610 10750018 15941674 33005030 21969602 15520013 10064605 21575865 26446488
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
NHEJ1 DEF6 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
NHEJ1 YBX2 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
NHEJ1 MT1F â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
TRMT6 TRMT61A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
NHEJ1 TPM1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
PAXX HDHD5 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
NHEJ1 MSMO1 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
NHEJ1 GATM â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
NHEJ1 CDC20 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
NHEJ1 NDUFB8 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
NHEJ1 NSA2 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
NHEJ1 EIF1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
NHEJ1 SDC4 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
POLM NDUFA4 â—¼   KO_DOWN_REGULATES ✅ - -0.92 0.91 PKG 28854368
ATM HMGCR â—¼   KO_DOWN_REGULATES ✅ - -0.92 0.91 PKG 28854368
XRCC4 HMGCR â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
NHEJ1 CRIPT â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
NHEJ1 CTPS2 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
NHEJ1 ZNF639 â—¼   KO_UP_REGULATES ✅ + 0.92 0.92 PKG 28854368
XRCC4 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
NHEJ1 CAVIN1 â—¼   KO_UP_REGULATES ✅ + 0.92 0.92 PKG 28854368
NHEJ1 MT-ND5 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
RPS27A TAB2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
NHEJ1 HDHD5 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
NHEJ1 XRCC5 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NHEJ1 CLIP2 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
NHEJ1 JADE2 â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
ATM MCAM â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
NHEJ1 FTL â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
PCNA RPS27A â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
PCCA PCCB â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
NHEJ1 STX6 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
NHEJ1 NUFIP1 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
NHEJ1 ATAD2 â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
NHEJ1 PDLIM7 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
XRCC4 REEP6 â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
PCNA POLM â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EIF1 RPS27A â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
NHEJ1 GCA â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
NHEJ1 ACADVL â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
NHEJ1 RPS6KA1 â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
COX6A1 COX6C â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
SUMO2 TDG â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
TDG POLL â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
ATM NODAL â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
HSPG2 NID1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
XRCC4 TWSG1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
PAXX SLC2A13 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
NHEJ1 PLBD1 â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
PCNA POLL â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
POLM ERVH48-1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
XRCC4 PRELID1 â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
NHEJ1 VWDE â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
NHEJ1 PPDPF â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
NHEJ1 PYGL â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
NHEJ1 PTMS â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
ATM YBX2 â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
H2AFY2 DND1 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
PAXX GCAT â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
XRCC4 PYGL â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
NHEJ1 DIDO1 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
NHEJ1 PGM2L1 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
NHEJ1 NOP53 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
POLM TMEM230 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
POLM NEBL â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
NHEJ1 SDHA â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
XRCC4 CRIP1 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
NHEJ1 TWSG1 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NHEJ1 DBI â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
NHEJ1 DHRS11 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
VPS11 VPS33A â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NHEJ1 C1orf122 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
TDG PAIP2 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
ATM CDC6 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
VPS33A VPS41 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS11 VPS18 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS11 VPS41 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS18 VPS33A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
VPS18 VPS41 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ATM SLC4A2 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
NHEJ1 MCAM â—¼   KO_UP_REGULATES ✅ + 0.99 0.99 PKG 28854368
RPL23A RPS27A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TDG LEFTY1 â—¼   KO_UP_REGULATES ✅ + 0.99 0.99 PKG 28854368
PRELID1 TRIAP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
TRMT6 TRMT61A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PCNA ATR â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA ATR â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA POLL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12368291 11784855 16174846 16189514 12081642
XRCC5 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H2AX ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATR H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 20461094 20976184 20471486 22224778 17303408 28797244 18677104 19622404 15798197 19793801 9488723 20860841 12919958 18158901 20165693 20936109 22002605 26114388 29114052 21283714 22819196 19282663 24893124 17116885 22531632 17582221 30013081 25438756 26019182 17384638 19647519 20205745 23166506 25852739 18471973 27442013 22247744 29584802 20542002 19875294 25249630 20368801 15459660 27332952 27715493 19772495 25247188 17296725 11877377 14643438 24813610 20613862 17102137 20847938 21148072 23443128 27431324 29163782 23754961 17690115 15975956 18663141 21787120 22545090 27077811 19781914 27164092
PRKDC H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 107.0 1.0 Omnipath 18454178 9488723 19321613 21930799 19305155 25487737 22819196 20493860 17570479 12607005 16673875 26976643 17723002 21151168 16039583 21514376 26438602 19049966 20368801 23916969 16935931 27919340 17923115 16061642 18438399 20157519 20461094 21690091 24253929 19531483 26960975 25168287 18758438 19268590 27813335 25690891 17210576 26748709 18406329 23972723 17412408 34429760 27551505 12692309 29221122 20703100 16861886 25070753 27332952 33691101 33863809 23653357 21283714 16788066 19781914 20205745 20860841 21389100 16148027 20116089 15610743 20192759 20224553 14627815 24893124 10734083 20488183 23185622 18157161 33945602 30573684 12766154 25699710 18755145 27738310 10477747 34504648 16820894 20356835 19014481 20713529 17525342 23671119 26114388 23355489 28790110 23678292 20118229 23166506 33986864 15604242 16377563 20609246 12907603 26119999 25072018 15289343 23891091 25269479 23620287 33731502 22972376 34282773 26578593
ATM H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 197.0 1.0 Omnipath 27410735 28544233 16426903 28797244 9488723 23847653 30197789 21930799 18158901 21693595 18848500 22819196 15603757 16760673 17570479 24688021 24793032 27458206 16531125 22028490 30154456 19230794 23202908 25852739 19059218 26073471 22247744 28259974 29584802 25691887 19049966 20368801 26700820 29386061 28124509 20613862 27550454 20847938 27388041 27752097 23269287 24480460 22237206 20461094 20971043 26941327 18285803 21690091 15279774 23891287 25847270 24490130 25349305 26906421 20637859 26314960 15286739 27780918 20454618 30013081 28671946 25218945 23742011 26391293 23972723 23382699 26416514 27442013 20703100 24726884 26512707 27332952 29641431 25287622 26295265 14643438 29163809 25264544 19895790 26504743 26113859 27431324 28790385 18413980 21283714 21787120 20205745 19781914 25093845 27135971 23227178 22224778 20923785 20860841 24244154 23386996 30065307 16858402 11879731 28009280 23343929 20192759 22761798 26855420 24378750 20068231 20580718 14504478 24893124 29048667 25661368 26860083 26019182 20488183 28764946 22205726 23977391 18471973 19591958 28239143 20542002 17525332 20495376 18755145 23050241 17782711 11571274 19473884 28431265 25742493 18248856 17690115 20684759 26317467 21727091 24651472 25827888 27164092 28587922 20976184 30723510 20471486 23772364 29794999 11893489 19014481 20165693 26671524 16997395 20936109 26114388 23845989 15138496 22761813 23355489 27455285 28943310 21348461 19647519 23678292 23166506 28099474 29434792 25249630 25269479 27310012 15177039 22559321 26045162 20865059 22972376 21148072 26760771 21188122 22962268 22768044 26711340 20460517 27845910 28855246
H2AX TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 20075863 18001824 21317870 12447390 17024177 18001825 21566653 12607005 12697768 21623170
LIG4 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
LIG4 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
LIG4 XRCC4 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 11163244 12032095 12471202 15385968 15703371 16439205 16697054 17088286 17638872 18077224 19346677 19473888 19546231 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
LIG4 XRCC4 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 11163244 12032095 12471202 15385968 15703371 16439205 16697054 17088286 17638872 18077224 19346677 19473888 19546231 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PRKDC LIG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15194694 15941674 17570479
XRCC4 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC4 DCLRE1C â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC4 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
XRCC6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
ATM DCLRE1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15723659 25842165 15574327 15456891 16874298 15468306
ATM TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16223874 17525332 15314656
ATM FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17525332 26774286
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATR CDC6 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC6 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC6 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12186630 22592045 22057367 24500207 18077418 16908529 15507430 29309644
XRCC5 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
XRCC6 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
DCLRE1C POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
DCLRE1C POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
DCLRE1C NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC DCLRE1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17242184 15723659 11955432 16600297 23163657 22529269 16874298 21641068 19423708 15936993 1660029
FGF2 SDC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9556568 20382221 9012653 8621465 16982797 8609172
FGF2 SDC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20382221 8621465 16982797 1101561416982790 8609172 11015614
MT-ND5 NDUFB8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
MT-ND5 NDUFA4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
MT-ND5 NDUFB8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
MT-ND5 NDUFA4 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
MT-ND5 NDUFA4 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
MT-ND5 NDUFB8 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFB8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFB8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
XRCC5 NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC6 NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
NHEJ1 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
NHEJ1 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC5 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC6 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC6 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC5 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
RAP1A TERF2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
RAP1A TERF2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
XRCC6 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NHEJ1 LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
PAXX ECHDC3 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
NHEJ1 TRAPPC13 â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
NHEJ1 EEF1E1 â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
NHEJ1 KIF18B â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
NHEJ1 RPL7L1 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
ATM PTMS â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
NHEJ1 LAMB2 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
NHEJ1 PDZD4 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
NHEJ1 FERMT1 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
NHEJ1 CD81 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
NHEJ1 FAHD2A â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
NHEJ1 CHKA â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
TDG FGF2 â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
PAXX SCRN2 â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
NHEJ1 COX7A2L â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
NHEJ1 TRIAP1 â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
POLM SDC4 â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
NHEJ1 EML2 â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
XRCC4 STX6 â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
NHEJ1 ALAS1 â—¼   KO_UP_REGULATES ✅ + 1.03 1.03 PKG 28854368
NHEJ1 DOP1B â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
NHEJ1 ZNF765 â—¼   KO_UP_REGULATES ✅ + 1.03 1.03 PKG 28854368
NHEJ1 GNG7 â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
NHEJ1 RASSF3 â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
POLM NODAL â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
NHEJ1 QPRT â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
NHEJ1 COX6A1 â—¼   KO_UP_REGULATES ✅ + 1.05 1.05 PKG 28854368
NHEJ1 COL6A1 â—¼   KO_DOWN_REGULATES ✅ - -1.06 1.05 PKG 28854368
POLM TIMM13 â—¼   KO_DOWN_REGULATES ✅ - -1.06 1.05 PKG 28854368
NHEJ1 HECTD3 â—¼   KO_UP_REGULATES ✅ + 1.05 1.05 PKG 28854368
NHEJ1 ACY1 â—¼   KO_DOWN_REGULATES ✅ - -1.06 1.05 PKG 28854368
XRCC4 FADS2 â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
NHEJ1 AHNAK â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
NHEJ1 TERF2 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
NHEJ1 PCCA â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
NHEJ1 NIPSNAP1 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
NHEJ1 CA2 â—¼   KO_UP_REGULATES ✅ + 1.08 1.08 PKG 28854368
NHEJ1 ACTR8 â—¼   KO_UP_REGULATES ✅ + 1.08 1.08 PKG 28854368
NHEJ1 VPS11 â—¼   KO_DOWN_REGULATES ✅ - -1.09 1.08 PKG 28854368
NHEJ1 VPS41 â—¼   KO_DOWN_REGULATES ✅ - -1.09 1.08 PKG 28854368
NHEJ1 REEP6 â—¼   KO_DOWN_REGULATES ✅ - -1.09 1.08 PKG 28854368
XRCC4 PRAF2 â—¼   KO_DOWN_REGULATES ✅ - -1.1 1.09 PKG 28854368
NHEJ1 ESF1 â—¼   KO_DOWN_REGULATES ✅ - -1.1 1.09 PKG 28854368
NHEJ1 TRMT6 â—¼   KO_DOWN_REGULATES ✅ - -1.1 1.09 PKG 28854368
PAXX PDCD4 â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
NHEJ1 NDUFA4 â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
NHEJ1 PDCD4 â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368
NHEJ1 PHYH â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368
POLM NIPSNAP1 â—¼   KO_UP_REGULATES ✅ + 1.11 1.11 PKG 28854368
NHEJ1 SCRN2 â—¼   KO_DOWN_REGULATES ✅ - -1.12 1.11 PKG 28854368
NHEJ1 PAAF1 â—¼   KO_DOWN_REGULATES ✅ - -1.12 1.11 PKG 28854368
NHEJ1 BCL2L1 â—¼   KO_UP_REGULATES ✅ + 1.11 1.11 PKG 28854368
XRCC4 SLC4A2 â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
XRCC4 CDC20 â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
NHEJ1 GAA â—¼   KO_DOWN_REGULATES ✅ - -1.13 1.12 PKG 28854368
XRCC4 ACTR8 â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
NHEJ1 NODAL â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
TDG ANXA3 â—¼   KO_UP_REGULATES ✅ + 1.13 1.13 PKG 28854368
NHEJ1 VPS33A â—¼   KO_DOWN_REGULATES ✅ - -1.14 1.13 PKG 28854368
NHEJ1 NEBL â—¼   KO_UP_REGULATES ✅ + 1.13 1.13 PKG 28854368
NHEJ1 SLC4A2 â—¼   KO_UP_REGULATES ✅ + 1.13 1.13 PKG 28854368
NHEJ1 GRAMD1A â—¼   KO_DOWN_REGULATES ✅ - -1.15 1.14 PKG 28854368
ATM ACAD10 â—¼   KO_UP_REGULATES ✅ + 1.14 1.14 PKG 28854368
XRCC4 CLIP2 â—¼   KO_DOWN_REGULATES ✅ - -1.15 1.14 PKG 28854368
NHEJ1 THY1 â—¼   KO_DOWN_REGULATES ✅ - -1.15 1.14 PKG 28854368
NHEJ1 SLC35A2 â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
POLM PAIP2 â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
NHEJ1 MME â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
NHEJ1 DPAGT1 â—¼   KO_DOWN_REGULATES ✅ - -1.17 1.16 PKG 28854368
NHEJ1 RHOT1 â—¼   KO_DOWN_REGULATES ✅ - -1.17 1.16 PKG 28854368
NHEJ1 ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -1.18 1.17 PKG 28854368
NHEJ1 DND1 â—¼   KO_UP_REGULATES ✅ + 1.17 1.17 PKG 28854368
NHEJ1 SLC4A7 â—¼   KO_DOWN_REGULATES ✅ - -1.18 1.17 PKG 28854368
NHEJ1 MRFAP1 â—¼   KO_UP_REGULATES ✅ + 1.18 1.18 PKG 28854368
TDG SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
NHEJ1 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
NHEJ1 ERVH48-1 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
TDG TWSG1 â—¼   KO_UP_REGULATES ✅ + 1.18 1.18 PKG 28854368
TDG AHNAK â—¼   KO_UP_REGULATES ✅ + 1.2 1.2 PKG 28854368
ATM LMNA â—¼   KO_DOWN_REGULATES ✅ - -1.21 1.2 PKG 28854368
NHEJ1 LMNA â—¼   KO_UP_REGULATES ✅ + 1.2 1.2 PKG 28854368
NHEJ1 IDH2 â—¼   KO_DOWN_REGULATES ✅ - -1.22 1.21 PKG 28854368
XRCC4 DHTKD1 â—¼   KO_DOWN_REGULATES ✅ - -1.22 1.21 PKG 28854368
NHEJ1 LZTS3 â—¼   KO_DOWN_REGULATES ✅ - -1.22 1.21 PKG 28854368
NHEJ1 ACYP1 â—¼   KO_DOWN_REGULATES ✅ - -1.23 1.22 PKG 28854368
NHEJ1 RIPOR2 â—¼   KO_UP_REGULATES ✅ + 1.22 1.22 PKG 28854368
NHEJ1 TAB2 â—¼   KO_UP_REGULATES ✅ + 1.22 1.22 PKG 28854368
TDG PDCD4 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
NHEJ1 CLYBL â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
ATM PCCB â—¼   KO_UP_REGULATES ✅ + 1.23 1.23 PKG 28854368
NHEJ1 CTH â—¼   KO_DOWN_REGULATES ✅ - -1.25 1.24 PKG 28854368
NHEJ1 PRSS1 â—¼   KO_DOWN_REGULATES ✅ - -1.26 1.25 PKG 28854368
TDG YBX2 â—¼   KO_DOWN_REGULATES ✅ - -1.26 1.25 PKG 28854368
NHEJ1 PLOD2 â—¼   KO_DOWN_REGULATES ✅ - -1.26 1.25 PKG 28854368
XRCC4 TSPYL1 â—¼   KO_UP_REGULATES ✅ + 1.25 1.25 PKG 28854368
XRCC4 PTMS â—¼   KO_DOWN_REGULATES ✅ - -1.26 1.25 PKG 28854368
NHEJ1 GCAT â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
NHEJ1 MARCKS â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
TDG REEP6 â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
NHEJ1 NEU1 â—¼   KO_UP_REGULATES ✅ + 1.26 1.26 PKG 28854368
NHEJ1 PRKAB2 â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
XRCC4 TDG â—¼   KO_UP_REGULATES ✅ + 1.27 1.27 PKG 28854368
NHEJ1 DDX5 â—¼   KO_UP_REGULATES ✅ + 1.28 1.28 PKG 28854368
NHEJ1 MAPK6 â—¼   KO_DOWN_REGULATES ✅ - -1.29 1.28 PKG 28854368
NHEJ1 ACSF2 â—¼   KO_DOWN_REGULATES ✅ - -1.29 1.28 PKG 28854368
ATM CYR61 â—¼   KO_DOWN_REGULATES ✅ - -1.3 1.29 PKG 28854368
NHEJ1 NCS1 â—¼   KO_DOWN_REGULATES ✅ - -1.31 1.3 PKG 28854368
NHEJ1 PIK3R2 â—¼   KO_DOWN_REGULATES ✅ - -1.31 1.3 PKG 28854368
NHEJ1 SDC2 â—¼   KO_UP_REGULATES ✅ + 1.31 1.31 PKG 28854368
NHEJ1 COX6C â—¼   KO_UP_REGULATES ✅ + 1.31 1.31 PKG 28854368
NHEJ1 VPS18 â—¼   KO_DOWN_REGULATES ✅ - -1.32 1.31 PKG 28854368
POLM PLBD1 â—¼   KO_UP_REGULATES ✅ + 1.32 1.32 PKG 28854368
NHEJ1 KIAA1191 â—¼   KO_DOWN_REGULATES ✅ - -1.34 1.33 PKG 28854368
NHEJ1 DCAF11 â—¼   KO_DOWN_REGULATES ✅ - -1.34 1.33 PKG 28854368
POLM SERF2 â—¼   KO_DOWN_REGULATES ✅ - -1.35 1.34 PKG 28854368
NHEJ1 CRIP1 â—¼   KO_UP_REGULATES ✅ + 1.34 1.34 PKG 28854368
NHEJ1 PRELID1 â—¼   KO_UP_REGULATES ✅ + 1.34 1.34 PKG 28854368
XRCC4 MME â—¼   KO_UP_REGULATES ✅ + 1.35 1.35 PKG 28854368
PAXX TAGLN â—¼   KO_DOWN_REGULATES ✅ - -1.36 1.35 PKG 28854368
NHEJ1 P3H3 â—¼   KO_DOWN_REGULATES ✅ - -1.37 1.36 PKG 28854368
NHEJ1 NID1 â—¼   KO_DOWN_REGULATES ✅ - -1.38 1.37 PKG 28854368
NHEJ1 CDS2 â—¼   KO_DOWN_REGULATES ✅ - -1.39 1.38 PKG 28854368
NHEJ1 CHTF8 â—¼   KO_DOWN_REGULATES ✅ - -1.39 1.38 PKG 28854368
NHEJ1 ABRACL â—¼   KO_UP_REGULATES ✅ + 1.39 1.39 PKG 28854368
XRCC4 PLBD1 â—¼   KO_DOWN_REGULATES ✅ - -1.4 1.39 PKG 28854368
NHEJ1 HSPG2 â—¼   KO_DOWN_REGULATES ✅ - -1.42 1.41 PKG 28854368
PRKDC PRSS1 â—¼   KO_UP_REGULATES ✅ + 1.42 1.42 PKG 28854368
PRKDC ANXA3 â—¼   KO_DOWN_REGULATES ✅ - -1.43 1.42 PKG 28854368
NHEJ1 DHTKD1 â—¼   KO_DOWN_REGULATES ✅ - -1.43 1.42 PKG 28854368
TP53BP1 NRK â—¼   KO_UP_REGULATES ✅ + 1.42 1.42 PKG 28854368
PAXX LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -1.44 1.43 PKG 28854368
XRCC4 SLC4A7 â—¼   KO_DOWN_REGULATES ✅ - -1.45 1.44 PKG 28854368
NHEJ1 DPP7 â—¼   KO_DOWN_REGULATES ✅ - -1.45 1.44 PKG 28854368
TDG FADS2 â—¼   KO_UP_REGULATES ✅ + 1.44 1.44 PKG 28854368
TDG TAGLN â—¼   KO_UP_REGULATES ✅ + 1.44 1.44 PKG 28854368
TP53BP1 CAVIN1 â—¼   KO_UP_REGULATES ✅ + 1.46 1.46 PKG 28854368
NHEJ1 ALG10 â—¼   KO_DOWN_REGULATES ✅ - -1.48 1.47 PKG 28854368
NHEJ1 CYR61 â—¼   KO_UP_REGULATES ✅ + 1.48 1.48 PKG 28854368
TDG NES â—¼   KO_UP_REGULATES ✅ + 1.48 1.48 PKG 28854368
PRKDC ATM â—¼   KO_DOWN_REGULATES ✅ - -1.5 1.49 PKG 28854368
NHEJ1 CNN1 â—¼   KO_UP_REGULATES ✅ + 1.5 1.5 PKG 28854368
NHEJ1 PTPRA â—¼   KO_DOWN_REGULATES ✅ - -1.51 1.5 PKG 28854368
NHEJ1 H2AFY2 â—¼   KO_DOWN_REGULATES ✅ - -1.51 1.5 PKG 28854368
XRCC4 SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.51 1.5 PKG 28854368
NHEJ1 COMMD9 â—¼   KO_UP_REGULATES ✅ + 1.51 1.51 PKG 28854368
XRCC4 LIG4 â—¼   KO_DOWN_REGULATES ✅ - -1.52 1.51 PKG 28854368
ATM NES â—¼   KO_DOWN_REGULATES ✅ - -1.52 1.51 PKG 28854368
NHEJ1 FGF2 â—¼   KO_UP_REGULATES ✅ + 1.54 1.54 PKG 28854368
NHEJ1 FASTKD5 â—¼   KO_DOWN_REGULATES ✅ - -1.55 1.54 PKG 28854368
NHEJ1 HMGCR â—¼   KO_UP_REGULATES ✅ + 1.54 1.54 PKG 28854368
POLM C20orf27 â—¼   KO_UP_REGULATES ✅ + 1.55 1.55 PKG 28854368
POLM CDC6 â—¼   KO_DOWN_REGULATES ✅ - -1.56 1.55 PKG 28854368
NHEJ1 C20orf27 â—¼   KO_DOWN_REGULATES ✅ - -1.56 1.55 PKG 28854368
NHEJ1 TMEM230 â—¼   KO_DOWN_REGULATES ✅ - -1.56 1.55 PKG 28854368
NHEJ1 PEAK1 â—¼   KO_DOWN_REGULATES ✅ - -1.57 1.56 PKG 28854368
NHEJ1 MACROD1 â—¼   KO_DOWN_REGULATES ✅ - -1.59 1.58 PKG 28854368
ATM AHNAK â—¼   KO_DOWN_REGULATES ✅ - -1.59 1.58 PKG 28854368
XRCC4 PDCD4 â—¼   KO_DOWN_REGULATES ✅ - -1.6 1.59 PKG 28854368
NHEJ1 SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.62 1.61 PKG 28854368
NHEJ1 TAGLN â—¼   KO_UP_REGULATES ✅ + 1.62 1.62 PKG 28854368
NHEJ1 MAT2B â—¼   KO_DOWN_REGULATES ✅ - -1.64 1.63 PKG 28854368
POLM RIPOR2 â—¼   KO_DOWN_REGULATES ✅ - -1.65 1.64 PKG 28854368
NHEJ1 PCNA â—¼   KO_DOWN_REGULATES ✅ - -1.66 1.65 PKG 28854368
TDG CDC6 â—¼   KO_UP_REGULATES ✅ + 1.65 1.65 PKG 28854368
NHEJ1 HMGCL â—¼   KO_DOWN_REGULATES ✅ - -1.68 1.67 PKG 28854368
NHEJ1 NES â—¼   KO_UP_REGULATES ✅ + 1.67 1.67 PKG 28854368
NHEJ1 PPP3R1 â—¼   KO_DOWN_REGULATES ✅ - -1.69 1.68 PKG 28854368
NHEJ1 CDC6 â—¼   KO_UP_REGULATES ✅ + 1.68 1.68 PKG 28854368
ATM CAVIN1 â—¼   KO_DOWN_REGULATES ✅ - -1.7 1.69 PKG 28854368
NHEJ1 MTPN â—¼   KO_DOWN_REGULATES ✅ - -1.73 1.72 PKG 28854368
ATM SLC16A3 â—¼   KO_UP_REGULATES ✅ + 1.73 1.73 PKG 28854368
NHEJ1 USP3 â—¼   KO_DOWN_REGULATES ✅ - -1.75 1.74 PKG 28854368
ATM ANXA3 â—¼   KO_DOWN_REGULATES ✅ - -1.82 1.81 PKG 28854368
PAXX NIPSNAP1 â—¼   KO_UP_REGULATES ✅ + 1.82 1.82 PKG 28854368
XRCC4 MACROD1 â—¼   KO_DOWN_REGULATES ✅ - -1.86 1.85 PKG 28854368
XRCC4 KIF18B â—¼   KO_UP_REGULATES ✅ + 1.95 1.95 PKG 28854368
XRCC4 FGF2 â—¼   KO_UP_REGULATES ✅ + 1.99 1.99 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
PAXX SLC16A3 â—¼   KO_UP_REGULATES ✅ + 2.28 2.28 PKG 28854368
H2AFY2 RBM46 â—¼   KO_DOWN_REGULATES ✅ - -2.51 2.5 PKG 28854368
XRCC4 CDC6 â—¼   KO_UP_REGULATES ✅ + 2.56 2.56 PKG 28854368
PAXX NDUFA4 â—¼   KO_DOWN_REGULATES ✅ - -2.58 2.57 PKG 28854368
ATM TAGLN â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.6 PKG 28854368
ATM LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -2.78 2.77 PKG 28854368
H2AFY2 H2AFY2 â—¼   KO_DOWN_REGULATES ✅ - -3.83 3.82 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368