RECQL4
|
POLB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19567405
|
NES
|
COL5A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SP1
|
ASCL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20599619
17728141
|
SP1
|
ATM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15837784
11466608
|
NES
|
CCSER2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SP3
|
CD2AP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21604172
|
SP1
|
CD2AP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18396147
|
FOSB
|
CDK5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11268215
16242410
|
EGR1
|
CDK5R1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15289351
|
CTCF
|
WT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24534946
|
DMTF1
|
EGR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19816943
|
NES
|
EBF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SP1
|
EGR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20121949
7384875
|
NR2F1
|
EGR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10082539
24227652
|
EGR1
|
IMPDH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7896827
|
EGR1
|
TCF4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18798221
|
EOMES
|
PAX6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22735158
19521500
|
NES
|
FAM81B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
FOXA1
|
NES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19916800
22783724
|
FOXA1
|
KRT7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20043065
|
TDP2
|
GOLGA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
GOLGA2
|
TDP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
HSP90AA1
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18538669
6550889
|
HIF1A
|
HSP90AA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14726529
20068160
|
HIF1A
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19934262
15780936
|
SP1
|
IMPDH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7896827
|
NES
|
KRT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
VIM
|
KRT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SOX17
|
LAMA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19052383
15220343
|
SP1
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18173747
|
WT1
|
MYCN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10470095
|
NES
|
TNIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SP1
|
NES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15135078
19245830
|
RBPJ
|
NES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17217625
15979417
|
WT1
|
NES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17912546
18212735
|
NEUROD1
|
NES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11029621
22525134
|
ZFHX3
|
NEUROD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16251211
|
NKX2-1
|
TTF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11046146
9588495
|
NR2F1
|
POU5F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8289793
7823919
|
SP1
|
PAX6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11574690
|
SP1
|
WT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12683994
18064385
|
TP63
|
TCF4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22232078
|
TCF4
|
VIM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12750294
|
SP3
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
12414801
11517158
10825178
16734381
9329821
23825960
12200149
15247906
|
POLB
|
SATB1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.82
|
0.81
|
PKG
|
28854368
|
HIF1A
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.81
|
STRING
|
36370105
|
MYC
|
CHD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
35140242
29467282
|
MYC
|
CTBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
34147029
|
MYC
|
EIF3I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
TDG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
26496610
|
VSX2
|
PAX6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
11069920
|
SOX2
|
UBR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30894683
23667531
|
ATM
|
MDC1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
12607003
|
MRM1
|
UBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
MRM1
|
UBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
MDC1
|
CHD7
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.84
|
0.83
|
PKG
|
28854368
|
SHPRH
|
NES
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.84
|
0.83
|
PKG
|
28854368
|
MYC
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
EGR1
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12569082
20121949
|
MYC
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15071503
28205554
28628118
|
ASCL1
|
TCF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.84
|
STRING
|
36370105
|
MDC1
|
LAMA1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.85
|
0.85
|
PKG
|
28854368
|
MYCN
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
20697349
18003922
21123453
|
NHEJ1
|
TDG
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.86
|
0.86
|
PKG
|
28854368
|
TDG
|
EBF2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.87
|
0.86
|
PKG
|
28854368
|
POU2F1
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
POU2F1
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
SOX2
|
CHD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
35140242
28794006
23667531
21532573
|
SP1
|
SP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ATM
|
LAMA1
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.88
|
0.88
|
PKG
|
28854368
|
MDC1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29656893
26734725
12607005
14519663
18006705
28943310
|
TDP2
|
NES
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.9
|
0.89
|
PKG
|
28854368
|
MYC
|
POLB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
UBR1
|
RECQL4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15317757
20096650
|
UBR2
|
RECQL4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15317757
20096650
|
CAPN1
|
CDK5R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25969760
10830966
|
CTCF
|
NES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
MYCN
|
EOMES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16093321
|
MYC
|
HSP90AA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
28914785
12644583
|
RBPJ
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18490439
10644343
16847353
|
WT1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15286719
17634147
20842112
|
MYC
|
NEFM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11274368
16713569
|
SP3
|
MYCN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14567977
14645238
|
MYCN
|
NES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15117961
|
POU3F2
|
NES
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18923447
19147497
18349072
|
SP3
|
NKX2-1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10684967
|
TDG
|
NKX2-1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17129768
11438542
|
WT1
|
NR5A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19001523
12130543
|
NR5A1
|
POU5F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17226773
10692469
15831456
|
SHPRH
|
RAD18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18719106
17130289
17108083
|
SP3
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9329821
15247906
10825178
|
RECQL5
|
NES
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.9
|
0.9
|
PKG
|
28854368
|
NEUROD1
|
TCF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
RECQL4
|
NES
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.91
|
0.9
|
PKG
|
28854368
|
HIF1A
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
CDK5R1
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
23543736
|
CDK5
|
CDK5R1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.94
|
0.94
|
Signor
|
18326489
|
POU5F1
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CDK5
|
CDK5R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ATM
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATM
|
MDC1
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
CDK5
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
12556884
16332722
16858402
17303408
19151707
20724832
21727086
21922195
23589330
23850759
|
ATM
|
MDC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATM
|
MDC1
|
â—¼ REGULATES
|
✅
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
CDK5
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17303408
23589330
16858402
19151707
27470939
16332722
12556884
21600237
21922195
|
ATM
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
28193847
21705321
22234877
12607003
12607005
22234878
17525332
18006705
|
ATM
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
23148884
18619531
22826432
27156884
29144413
29294106
23046908
17609267
18171990
|
ATM
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24366874
20023394
18769144
|
ATM
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
27245613
24681585
21095578
18971907
21095582
27027353
23573973
27068951
25956861
23707302
26942179
|
MYC
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
32.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
25002027
28536364
7575488
9618481
|
CDK5
|
CDK5R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
11583627
23602568
15689152
11389014
17036052
25076872
21220307
15890360
16189514
23979715
26186194
17591690
17762160
14521924
20133653
22654103
28637746
12223541
23543736
18326489
28077789
17121855
|
CDK5
|
STXBP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17716669
|
CTCF
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
10625678
8649389
2284094
12032779
19568426
24725430
12524457
8246978
12897849
9591631
1795697
|
SP1
|
EGR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20427719
18044710
9282327
8349585
10826704
10082539
12637574
|
EGR1
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18506761
20448047
|
MYC
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10432118
11274345
11283614
11875494
16327802
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21093321
21372296
21406394
21765015
2191300
22067385
22461508
23124025
23390297
25002027
|
HIF1A
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20404562
23059786
19845622
18616527
15780936
21303984
|
MYC
|
IMPDH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18628958
18677108
|
TCF4
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10391247
11955436
11967263
12051714
15001769
15082531
15576399
16039586
17143292
17936032
19619488
20705860
22290435
22761862
23343194
24023259
25730849
7542250
8666229
|
SP1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11470523
9492315
2284094
8437848
7753559
8355712
2057364
|
TCF4
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
21533051
19778454
15928669
20133699
18852287
19561604
19662654
|
TCF4
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
19751508
7542250
11967263
22290435
19623618
23343194
11955436
22270359
22761862
16039586
15810077
17143292
12051714
8666229
22943793
15576399
21151179
16940750
17306568
17666529
21285352
19619488
|
SP1
|
MYCN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14567977
22815527
21123453
14645238
|
MYOG
|
MYF6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9056635
9186058
7852366
7739551
|
SP1
|
NKX2-1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10684967
15264213
|
WT1
|
NR5A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9815658
11207191
18445271
11278460
|
PAX6
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19666824
17825048
11358870
|
POU5F1
|
SOX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20505756
12136102
17324942
15988017
17068183
|
PPP1R13L
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
22538442
12524540
18275817
24714389
|
SP3
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
21554857
12509426
9632663
10362515
19223508
15857802
20096088
16806531
15854045
15118068
9788252
12773549
16617124
11517158
12554796
9666093
15869407
12888570
11287330
15541732
8845379
16574784
8070411
|
SP1
|
VIM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17663720
22227038
3419902
10777586
12771217
|
SHPRH
|
EBF2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.02
|
1.01
|
PKG
|
28854368
|
RECQL4
|
VIM
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.05
|
1.04
|
PKG
|
28854368
|
SHPRH
|
VIM
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.12
|
1.11
|
PKG
|
28854368
|
MDC1
|
NES
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.17
|
1.17
|
PKG
|
28854368
|
RAD18
|
SLC35F6
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.25
|
1.24
|
PKG
|
28854368
|
RECQL5
|
VIM
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.26
|
1.26
|
PKG
|
28854368
|
TDP2
|
VIM
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.37
|
1.36
|
PKG
|
28854368
|
MUS81
|
NES
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.36
|
1.36
|
PKG
|
28854368
|
POLB
|
NES
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.37
|
1.37
|
PKG
|
28854368
|
RAD18
|
NUTF2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.37
|
1.37
|
PKG
|
28854368
|
TDG
|
NES
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.48
|
1.48
|
PKG
|
28854368
|
ATM
|
NES
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.52
|
1.51
|
PKG
|
28854368
|
TREX1
|
NES
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.59
|
1.59
|
PKG
|
28854368
|
DDB2
|
NES
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.61
|
1.6
|
PKG
|
28854368
|
NHEJ1
|
NES
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.67
|
1.67
|
PKG
|
28854368
|
TREX1
|
VIM
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.67
|
1.67
|
PKG
|
28854368
|
NHEJ1
|
VIM
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.75
|
1.75
|
PKG
|
28854368
|
RAD18
|
VIM
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.95
|
1.94
|
PKG
|
28854368
|
TDP2
|
TDP2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.0
|
1.99
|
PKG
|
28854368
|
MUS81
|
VIM
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
2.02
|
2.02
|
PKG
|
28854368
|
MDC1
|
VIM
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
2.11
|
2.11
|
PKG
|
28854368
|
RAD18
|
NES
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.16
|
2.15
|
PKG
|
28854368
|
ATM
|
ATM
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.25
|
2.25
|
PKG
|
28854368
|
DDB2
|
VIM
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.33
|
2.32
|
PKG
|
28854368
|
ATM
|
VIM
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.44
|
2.43
|
PKG
|
28854368
|
TDG
|
VIM
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
2.48
|
2.48
|
PKG
|
28854368
|
RECQL4
|
RECQL4
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.61
|
2.61
|
PKG
|
28854368
|
MDC1
|
MDC1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.38
|
3.37
|
PKG
|
28854368
|
POLB
|
VIM
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
3.54
|
3.54
|
PKG
|
28854368
|
TDG
|
TDG
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.98
|
3.97
|
PKG
|
28854368
|
SHPRH
|
SHPRH
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-4.0
|
3.99
|
PKG
|
28854368
|
RAD18
|
RAD18
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-4.39
|
4.38
|
PKG
|
28854368
|
DDB2
|
DDB2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-5.71
|
5.7
|
PKG
|
28854368
|
NHEJ1
|
NHEJ1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-6.47
|
6.46
|
PKG
|
28854368
|
RECQL5
|
RECQL5
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-7.08
|
7.07
|
PKG
|
28854368
|
POLB
|
POLB
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-7.24
|
7.23
|
PKG
|
28854368
|