Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CLU APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EP300 HIPK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18695000 16917507
HIPK2 EP300 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16917507 5218981
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
USHBP1 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HIPK2 SUMO1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 5217735 15896780
SMAD3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
PROX1 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18948102 6787391
TAF1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7724524 9242374
HOXA1 NOTCH3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PKNOX1 HOXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 9582372
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
PIN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIN1 HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PIN1 CSNK2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11940573 5215253
PIN1 NANOG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20622153
AR HOXC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21047772 20610535
SOX2 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20384793 22902753
TCF7L2 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17468517 18655789
NANOG CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15983365
SMAD5 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD4 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12099698 15242331
SMAD3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AR SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20739403 20610535
SMAD3 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15292219
SMAD3 NANOG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21402155
NFIC TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15047811 8939900
PTK2B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SIX3 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17066077 16118513
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 NOTCH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
AR SMAD1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219486 17183365
TBP APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CSNK2A1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP PCNT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AR APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16987234
CSNK2A1 KANK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17476305 5219902
NANOG DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22795133
AP1M1 HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRAS HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VSX2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16492776 12466965
AR KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8423674 24172884
RB1 TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11094070 16713569
POU5F1 NANOG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17211451
SOX2 NANOG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17211451
PPIL4 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RBM4 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SOX2 ATOH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22340499 22292066
PROX1 ATOH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18652815
SOX2 ATOH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15846349
NFIA NEUROD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIB NEUROD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIX NEUROD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NEUROD1 NES â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11029621 22525134
NEUROD1 INS-IGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21781967 15862113
MAFA GCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18515495 19785038
PAX6 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23622063 15558475
EAF1 HOMER3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PKNOX1 PAX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20413611
MAFB MAFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24520122 18199433
NFIB NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
NFIA NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
PKNOX1 HOXB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10381567 16166636
GCM2 HOXA1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
EP300 SMAD5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16516194 16613856
SOX2 SUMO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17097055 25416956
SUMO1 MITF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22012259 16189514 16029420 10694430
SPAG5 DISC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 33961781
NAV1 DISC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 33961781
VSX2 PAX6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11069920
PIN1 UBXN2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
SOX2 NFIB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 21532573 28794006
ATOH1 TCF12 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
NEUROD1 TCF12 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
RB1 TAF1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NANOG SOX2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
EP300 RAN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12649209 33742100
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
SUMO1 UBE2K â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
TLK1 TLK2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
EP300 SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10205054 20851880 22365546 16613856 10673036
IPO13 RAN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23435562 17828378 21139563
PAX6 CDX2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10506141
PCNT DISC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12812986 15094396
SMAD4 SMAD5 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CSNK2A1 SIRT1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
SMAD4 EP300 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 25514493 18215124 9843571 14612423 10887155 22033265
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
LHX2 TCP11L1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
PAX3 IPO13 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 15143176
SMAD5 SMAD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10531362 16516194 16189514 15231748
NFIB NFIA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 33961781 26871637
APP CLU â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RB1 SMARCA4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PAX6 TBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 10359315
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HOXA1 PIN1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
EP300 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 10506141
EP300 HIPK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16917507 29170424
TLK1 TLK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32707033 33961781 10523312
HOXC8 LHX2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
IPO13 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15143176
SUMO1 HIPK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15958389 16253240 21145359 10535925 15896780 21192925 24637324 14609633
HIPK2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 12874272
SMARCA4 TCF7L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19571879 11532957 21654818
AR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24119295 21796528 17932034
AR CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 15790678
PIN1 SMAD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21988832 19920136 21685363 19122240
SMAD1 HOXC8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11139569 10224145
SMAD1 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 17183365 16189514 32296183 31467278 12167862 14701756 12874272 28468752 15761153 24412244 10531362 15231748 11700304 11779505 26555259 9436979 21454478
SMAD3 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 16189514 25514493 11927552 28443643 21988832 20211142 15084259 12732634 19768112 15467747 20142324 25609649 15922743 12917407 12419246 20564330 24382352 19139564 32296183 24157709 18729074 22442258 10092624 17283070 15350224 17591701 15761153 31591477 10995777 26555259 9892009 9311995 15588252 12167862 10878024 25910212 27703004 33990575 28115363 18055455 22310290 19135894 10531362 12794086 15231748 21297662 22045334 19917253 24584437 27107012 29892012 29997244 21532621 27845895 21597466 25502805 11114293 12543979 23788427
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
TBP APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8015372
POU5F1 DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22795133 30140294
AR TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9238003
AR MID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24913494 20610535
AR TKT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9719026 8807577
AR TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12799378 20610535
TBP RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9242374 10197586 9400991
TBP TKT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1846184 1323706 18094162
KRAS SPHK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12391145 10802064 12776187
VSX2 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15576400 15459106 10903182
PAX6 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11350962 16189514 12756174
MITF VSX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15576400 15459106 10903182
NEUROD1 ATOH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20661473 22292060 19609565
INSM1 NEUROD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11842116 16569215 24407176
NEUROD1 REG3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18192873 16522740 19770784
NEUROD1 MAFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20584984 17259388 17510498
NFIC NFIB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 9099724 35140242 33961781 25258084
NFIB NFIX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9099724 35140242 33961781 26871637
NFIB NFIX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9099724
CDK3 CKS1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CDK6 RB1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
POLR3C POLR3GL â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PAX6 MITF â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 16189514 11350962
HOXA1 TGFB1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
CCDC6 PIN1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
HOXA1 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
HOXA1 KRTAP9-3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
IPO13 RAN â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
KRTAP9-3 KRTAP9-8 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
SUMO1 SAE1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9920803 20164921 15660128 19246003 12941704 12924945
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
NANOG POU5F1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
DNMT1 RB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
SAE1 SUMO1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
POU5F1 SOX2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CDK3 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18669648 1756735 19118012 19690332 15084261 15838516 26832662
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9660747
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
PIN1 HIPK2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 12851404 23000554 11780126 11511362 11740489 24145406
SUMO1 HIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21145359 15896780 10535925 14609633
HIPK2 PAX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16407227
PIN1 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10391244 16713569 11090625
SUMO1 SAE1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 9920803 20164921 19107418 10187858 11481243 20501649
SUMO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14514699 23331499 21071413 12813045 12740389
TAF1 TBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TBP TAF1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 29111974 17375202 31753913 7680771 17967894 9311784 9858607 9674425 9153318 15870300 8995708 7597030 15564746 9603525 18391197 9660973 16713569 8858156 17884155 19240132
TAF1 TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16858867 11316804 9699517 15808844
RB1 TAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 9242374 16713569 7724524 9858607 11126356
RB1 CDK6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
NANOG CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22378194 17761754 19139263
CDK6 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 43.0 1.0 Omnipath 10498883 9315635 17303408 11416152 15081408 16236519 19690332 16936279 11520855 16107892 19413330 15279786 16360038 9190208 14627988 7575488 24417566 8822197 10385618 9736735 9139732 7736585 19075565 29372101 18590585 27507850 22682621 20068082 9425340 25549286 18786381 17660363 15809340 27811360 10778858 9380698
RAN AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10400640 16713569 18565325
CDX2 POU5F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15788452 23649632 20485553 20081188 18067887
CDX2 GCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9933606 17901057 11773447 14765989 17263687 10506141 16574312
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   PROTEIN_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10964912 15647271 10843986 21968601
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
SMAD5 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20957627 23331499 14534577 16516194 16189514 10531362 15231748
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
TGFB1 SMAD3 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
TGFB1 SMAD3 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
TGFB1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
SMAD3 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26553048 27974707 10708950 19214138
TGFB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21557273 24899689 24075003 24485922 28756206 32196115
SMAD3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 11248024 11280774 12226080 16713569 11707452
TGFB1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12867422 25241761 16189514 2119582
PAX6 SIX3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11069887 11069920 12072567
CSNK2A1 HNRNPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19651622 20058876 17081983 20166139 15687492 18691976 20068231 18452278 19664995 17693683 17287340 19413330 12564933 18669648 15302935
CSNK2A1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11711551 18452278
PAX3 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10982026 22290434 10480898 19074888 19403660 9500554 19026785 20925909 11237412 10942418 10644012 21965087 21519923 11830592
MITF PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9466887 23610061 17277739 15978250
POU5F1 NANOG â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20925113 17506876 16153702 20526341 19829295 22855527 17068183
POU5F1 NANOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18662995 22745796 15860457 20505756 18537119 19522013 18687992 17272500 18338330 17068183
POU5F1 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20505756 12136102 17324942 15988017 17068183
SOX2 NANOG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17068183 16153702 21816365 19829295
SOX2 NANOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22745796 23939864 15860457 18537119 17324942 19522013
NEUROD1 GCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15906379 21824254 20592023 19223471 9685329
ZGLP1 GCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331010 15566941 16522728 12727110 20804731 11035202 12167488 12401714
MAFB GCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21824254 20592023 17901057 16443760 18515495 18199433 17360442
BCL9L TCF7L2 â—¼   PHYSICAL_INTERACTION 20.0 1.0 Reactome 12163411 16169192 11955446 18347063 17458864 22186018 15294866 16005293 16510874 19487454 9490669 17425782 19493659 18498752 17052462 22190459 18404694 11988739 17428831 22617422
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
NFIB NFIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9099724 25258084 16189514