Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SNAP23 TLK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5212015 10588641
TLK1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11314006
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
H3C2 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19766566 8009287
ASF1B TLK1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
CUL4A DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 32235678
BATF3 TLK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HLF TLK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BATF3 HLF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
CHEK1 CUL4A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
TLK1 TLK2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
DYL1 TLK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 33961781 26496610
TLK1 DYL2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 32296183 33961781
DYL2 TLK2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 33961781 27173435
ASF1A ASF1B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
H3C2 ASF1A â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 7219095 19498464
ASF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
H3C2 ASF1A â—¼   PROXIMITY ✅ 0.88 0.88 mint 25281560
DYL1 TLK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 33961781 27173435 26496610
TLK1 TLK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32707033 33961781 10523312
DYNLL1 DYNLL2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
DYL1 DYL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 33961781 27173435 26344197
ASF1A TLK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 11470414 12660173 17940067 33961781 34079125
MAPK3 TFCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19237534
MAPK3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8197172
MDC1 NBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15377652 30179224 12607003 18678890 29656893 27590578 25064736 20460517 19804756 23115235 14519663 15201865 12607005 20224574 18001824 18583988
ASF1B TLK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17353931 33961781 11470414
ASF1B TLK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11470414 17353931 17940067 33961781 24981860 20016786
H3C2 ASF1B â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 7219095 19498464
ASF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
H3C2 ASF1B â—¼   PROXIMITY ✅ 0.9 0.9 mint 25281560
MDC1 NBN â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
ASF1A TLK1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
ASF1B TLK2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
ASF1A TLK2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
ASF1B ASF1A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12842904 22407294 26496610 24981860 34079125
ASF1A TLK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 11470414 26496610 33961781 24981860 34079125 20016786
CHEK1 TP53BP1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
NBN MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20224574 7891431
TLK2 ASF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11470414 24598821 29478807 26496610 20016786
ASF1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15664198 10759893 11985607
CHEK1 TLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 18159951 12660173 20068082 12955071 20068231 20581459 18669648 24376897
CHEK1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 18451105 20068082 23844048 12560483 18066052 20948546 21357687 18243098
CHEK1 TLK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12660173 20068082 12955071
MAPK3 MBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 10339476 16401070 1939237 1699809
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
MDC1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 15201865 20460517 23115235 14519663 18001824 18678890 19804756 18583988 19230643 12607003 12607005 20224574
TLK1 RAD9A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26658951 18940270 24376897
AURKA H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14583461 15108802 17938195 15249581 12234980 12588998 12082625
ASF1B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11985607 17353931 15664198 27753532 12842904