Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CENPA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 DAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ABL1 DDX41 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 AIRE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 SF3B4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PRKCA ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10713049
ABL1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19231300
TP53 AIMP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0800297105 18695251
MYC AIMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
ARAF YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TP53 CCAR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20160719 20074560
CDK9 CDC37 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
CDC37 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CDC37 SQSTM1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 21900206 2001699 8089645
CDC5L YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CDK9 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
CDK9 NCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
CLK2 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
COPS5 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24043623
COPS6 SMN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAG DDX39B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SF3A2 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
WBP11 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
MYC DDX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
TCF4 DOT1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
DOT1L TCF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
DOT1L CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
E2F1 ZEB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17655524
E2F1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14706452 18794899
E2F1 TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7734951
E2F1 MAP1LC3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18408756
E2F1 RRP1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20040599
EGFR E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16299810
HDAC1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17980157 18319725
E2F1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9368006
E2F1 HSPA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18840615
TBP EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9699517 8152794
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
EGFR ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24797263 20029029
EGFR PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 1845983
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
TCF4 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219834 17410209
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 DDX17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20663877
FUS MATR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27731383
EZH2 MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19749796 23349306
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
NDRG1 RYBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 NDRG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
OTUB1 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF113A CCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RRP1B CTCF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMARCE1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18238828 19785031
MYOD1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 17043109
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
SMAD1 SMARCE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SQSTM1 CUL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15983046 22872865
SQSTM1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NFKB1 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9762895
MAP1LC3A SQSTM1 â—¼   COLOCALIZATION 2.0 0.8 intact 19427866 7034152
JMJD6 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 24667498 1001819
HDAC3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16847267 0510834103
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
YBX1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12835324 16963428
TP53 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21900401
TP53 GSTK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15790310 17077087
TP53 DAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24217921 20943371
TP53 YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18504427 22417301
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
RCHY1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 5220017 17568776
JMJD6 TP53 â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 24667498 1001819
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
HDAC3 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18037959
YBX1 CUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218767 16797541
YBX1 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
GSK3B YBX1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16198352 5217974
SP1 YY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22553354
YY1 CTCF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9756895
YY1 SF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
ZNF207 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
U2AF2 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SRRM2 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3B4 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SRSF1 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
WBP11 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 CCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 CD2BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 PQBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 ACIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 BUB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 DDX42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 NCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 DDX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 CTNNBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 DDX46 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3B4 BCAS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
BCAS2 SF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
DDX42 SF3B4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
DDX17 SF3B4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SF3B4 CHERP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SF3B4 SF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SF3B4 CD2BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15105431 5217015
PRKCA ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15590896 10592173
ACTB POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10773068 435297
CALM1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
SP1 CALM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9348238 10945244
NCBP2 NCBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SNRPC DDX42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SNRPC AGGF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
AGGF1 CHERP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
CHERP SART1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
CHERP CCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
CD2BP2 SF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15105431 5217015
CTNNB1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18948405 15031118
SMAD3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11711431
SMAD3 RANBP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
SMAD3 SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20123992 21965288
SMAD3 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11740493
SMAD3 DGCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21102523
TYK2 PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219626 17290288
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
PPP1CA HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17008050
RCHY1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16914734
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
DAPK1 SGK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DAPK1 RCHY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
YWHAG TCF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TCF4 PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 ILK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19176380 24361375
SP1 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11133225 7499419
DDX3X SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16818630 33627125
PPP1CA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8288823 20186153
ALYREF AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18562279 0802533105
AKT1 PTK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15539407 20606012
NFKB1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18031796
PPP1CA AKT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288823 20186153
NFKB1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
NFKB1 CTCF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21912613
CTNNB1 VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16983094 0606850103
PRKCA HDAC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8307255 21952047
SMN1 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD1 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ACIN1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SRPK1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG CFAP20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG SRRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG SRRM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
RPL10 SRRM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CTNNB1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16219695
GSK3B CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
SMN1 HNRNPU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221091 8670859
TFCP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21655924 19966177
PPP1CA IKZF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21750978 19282287
WBP11 PPP1CA â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 22365833 8293266
TBP FUS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19841068
AQR PQBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SRPK2 DDX46 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
U2AF2 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
U2AF2 SRSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
U2AF2 SF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
U2AF2 DDX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
U2AF2 SRPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SF1 U2AF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10606272 16376933
SRPK2 CTNNBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RYBP FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WBP11 DDX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
WBP11 CTNNBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
WBP11 PQBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CDC5L SART1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CDC5L PPP1CA â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
ALYREF NCBP1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
BCAS2 SRRM2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
CACTIN CRNKL1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CHD4 EZH2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CREBBP TCF4 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CDC5L SRSF1 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
SMAD1 DDX5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18548003
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
DDX17 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 17226766 19995069 33742100 20663877
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
EP300 CHD4 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 26546801 30110629 32699137 15189737
NEDD8 OTUB1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 33665565 18954305 24654937
SRPK2 RRP1B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 26167880 33961781
CBX7 HDAC2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19706751 22214847
GSK3B SMAD1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25241761 18045539
CFTR YWHAG â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
BCAS2 SNRPC â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
BCAS2 CWC22 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CACTIN CWC22 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CTBP1 ZEB1 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
CRNKL1 SF3A2 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CWC27 SRRM1 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CDC5L DDX23 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
BCAS2 CACTIN â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
ACTB ARID1A â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
ARAF DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29777862 25852190
CFTR CDC37 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
STK4 CDC37 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24366813 23455922
CDC37 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16611982 24189400
SRRM2 CDC5L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
MYC CDC5L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
SF3A2 CDC5L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20467437 17332742
CDC5L CDK9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20467437 26209609
CRY1 CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26431207 32235678
CUL4B DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 34026424
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
DDX41 SRRM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 25920683
DDX41 DDX23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 25920683
ILK DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23455922 25852190
SRRM1 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16159877 26344197
VHL DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 21942715
VCAM1 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SRRM2 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
CUL4A DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 32235678
GSK3B DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 30711629
EGFR DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 28065597
DDX5 U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26641092
DDX5 AIRE â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27365398 20085707
DDX5 CHD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28977666 20676135
EGFR MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGFR ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
ACTB EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33742100 21988832
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
CTBP1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21102443 15834423 35016035 16122695
EP300 SMAD5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16516194 16613856
MYC MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
CUL1 MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 21145461
MATR3 BTF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 33644029
MATR3 AKAP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 26496610
MBD3 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24048479 30415952
MYC CPSF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC NXF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC DDX17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 20551172
MYC CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MYC CHD8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
OTUB1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32814053 18954305
CHD4 RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28977666 20926688
RRP1B DDX23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20926688
VCAM1 TOP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
LRRK2 PCNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
CUL4A NFKB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 30945288
IKZF1 CUL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SF3A2 DDX42 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12234937 17332742
SF3A2 CHERP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12234937 17332742
SF3A2 U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12234937 17332742
SRRM2 SF3B4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
SF3B4 DDX42 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 24981860
JMJD6 CHERP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CD2BP2 SART1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
MBD3 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 25123934
NR2E1 HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28420882 18391013
IKZF3 HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12015313 30760870
HDAC2 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
EZH2 HDAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23079660 21685935
LRRK2 AGO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20671708 17400507
NEDD8 DDX17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 24654937
ILK AKAP8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23455922 25852190
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
VCAM1 BUB3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
NXF1 WBP11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22658674 29395067
HDAC6 G3BP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18079183 21532619 32082291
VCAM1 G3BP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
G3BP1 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26777405
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ESR1 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308691 21182205 19805454 20348541
IKZF3 CHD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12015313 30760870
JMJD6 DDX46 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 CHD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CTBP1 EZH2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31041561 27634302
NFX1 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 31059266
VCAM1 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
JMJD6 U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CPSF6 U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26641092
U2AF2 DDX17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 26641092
U2AF2 CCAR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 26641092
SRPK2 CPSF6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 23602568
SRSF1 SRRM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 33961781
VCAM1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 DDX17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
DDX17 CTCF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30459231 24725430
SOX2 MBD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24048479 21532573
VCAM1 MBNL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CRNKL1 SF3B4 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
DDX23 SF3B4 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
TP53 YBX1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
SRRM2 ZC3H18 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
AKT1 GSK3B â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 15829723
AKT1 GSK3B â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 23552696
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
BCAS2 CWC27 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
AQR CWC27 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
SART1 SNRPC â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CDC37 DDX17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16611982 25036637 24189400
CDC5L FUS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20467437 29884807 25192599
CDC5L DISC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 90000000 31413325 17043677
CDK9 DDX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17643375 26209609
CDK9 CUL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11689688 12861003
CRY1 CUL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25756610 34237211 17463251 33961781
MATR3 DDX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 DDX17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 DDX3X â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
SMAD3 MEN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11274402 16189514
BCAS2 CRNKL1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
ESR1 SRPK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
ESR1 SRPK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
EZH2 CHD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28486105 28068325 24981860 26344197
CTBP1 CHD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 24981860
JMJD6 CPSF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24667498
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CHD3 TRIM28 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
LRRK2 YWHAG â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
PPP1CA RRP1B â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
EP300 VHL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CHD4 SMARCA4 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DDX3X FUS â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CTNNB1 SMAD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CACTIN CDC5L â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CDK9 TP53 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
SRPK1 DDX5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
MYC ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11839798 29467282
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
TOP1 DDX23 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 15848144
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
DERL1 CFTR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18555783 16901789 16954204 26618866
ESR1 CIRBP â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 PQBP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 EZH2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
CHD4 CHD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28977666 32744500 24981860 22939629 9885572
DGCR8 DDX17 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24581491 17765891
SRRM1 FUS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 12581738
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DDX5 ESR1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
GSK3B CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 16293724
RNF113A SRRM2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
SMARCA4 SP1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
GSK3B CDC37 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23455922 29568061 33961781
CUL4B HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
CUL4B HDAC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30737378 34026424 25189618
EP300 SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10205054 20851880 22365546 16613856 10673036
HDAC1 ERCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31722399 26496610 26030138
MYC HDAC3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23079660 31155734 22002311 18483244
TP53 PIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 12397362 5215850
CUL1 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
ARF6 ARRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11533043 16189514 11867621
HDAC2 IKZF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10204490 10357820 30760870 12015313
HDAC3 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29523594 20026773
ESR1 AKAP8 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21182205 33731348 31527615
IKZF1 TBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16713569 11959865
FUS DDX17 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27460707 29884807 26344197
PSMA3 VCP â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CALM1 ESR1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
HNRNPU POLR2A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
NEDD8 VHL â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CHD3 MBD3 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
DISC1 AIMP2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32296183 29961565
CDC5L CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20467437 21145461
CDC5L DDX41 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20467437 25920683
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
CUL4B DDX5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
MYC TBP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 15723054 8755740
OTUB1 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26752685 18954305
HDAC3 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31527615 16469706 14722073 26487511 20348541
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
DDX17 PTK6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32296183 31980649
SOX2 PIAS1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
SOX2 CHD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23667531 28794006
SRPK1 U2AF2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 33961781 9472028 23602568 32707033
SRPK2 SRRM2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32707033 26167880 33961781 23602568
SRPK2 SRSF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10196197 12565863 33961781 9472028 23602568
CDC5L SF3B4 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
DDX46 SF3B4 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
ACTB ACTL6A â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
SRPK2 SRSF1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
AKT1 CDC37 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
LRRK2 CDC37 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18367605 22612223 20642453 26355680 16321986 23075850
CDC5L BCAS2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 20467437 7945687
CDC5L SRSF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11101529 20467437 22939629
CDC5L U2AF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20467437 22939629 26641092 21536736
CLK2 SRRM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 26871637
CUL4B SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23238014 27634302
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
NXF1 DDX5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22658674 23143267 29395067
EGFR ARRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
MYC DDX20 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 17314511 29467282
MYC HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 22286234 30415952
MYC AKAP8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 17314511 30415952
MYC TOP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 30415952 29467282
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
SF3A2 SF3B4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12234937 26344197 17332742
ESR1 ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31527615 20308691 19805454 21182203 21182205 20348541
SUZ12 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24457600 26344197 22439931
HDAC1 VHL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
EZH2 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10581039 24981860 21685935 26344197
HDAC2 VHL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
HDAC2 SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 26344197 20075857
SOX2 HDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 21532573 23667531
VHL NEDD8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16503656 17353931 15060148 18323857 11024059
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
PIAS1 ESR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11117529 15666801 31527615
IKZF1 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 30760870 11003653 12015313 33961781
SRPK1 SRPK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32707033 21157427 33961781
ARID1A ARID1B â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DDX17 DDX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GABARAPL1 SQSTM1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CHD4 IKZF1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CALM1 EGFR â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CWC15 RNF113A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RNF113A SF3B4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CWC27 RNF113A â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RNF113A SF3A2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PIAS1 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CWC27 SRRM2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AIMP2 PARK2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
COPS5 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HDAC6 SQSTM1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 YY1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CHERP SF3A2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CDC37 LRRK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CWC22 RNF113A â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DDX17 SF1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
DDX42 SF3A2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SF3A2 SRSF1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CD2BP2 PPP1CA â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HDAC2 IKZF1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PPP1CA WBP11 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PIN1 POLR2A â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CHD3 CHD4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ACTL6A ARID1B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SRSF1 TOP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PQBP1 WBP11 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDC37 ARAF â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25036637 31980649 29777862 24189400 33961781 32707033
CDK9 CDC37 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32707033 25036637 24189400 33961781 20305087 26186194 24981860 27684187 23455922
CDC37 AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22504172 12176997 31980649 24869908
MYC CDK9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12944920 19818711 26687678 11673469 17700062 30415952
DDX39A DDX39B â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CUL1 E2F1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10559858 11245432
E2F1 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10734134 9468140 17980157 26468294 9468139
PTK6 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8940083 22973453 16273093
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
SP1 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15647279 19062177 10651903 11517158 23714681 10899165 16478997 11030335 24530506 34252870 28425985 31536933 32115405 17623675 10362258 16734381 17906698 22415975 12200149
FUS EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 30110629 33742100
TOP1 SRSF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9611241 15848144 20805487 12270705
CUL4A NEDD8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16503656 19617556 22474075 18274552 31973889 24654937 16620772 12481031 19295130 23201271 16964240 10597293 21145461 18247557
GSK3B SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21310903 18172167
HDAC1 CHD4 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 26949739
IKZF1 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23752268 16189514 30760870 10357820 12015313 10204490
HDAC2 SP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17312152 18059533 16713569 15713621 17894944 12091390 16036112 12151407 21159880 12176973 20697349
ILK AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 12149249 9736715 12176337 11445557 18339839 11825911 11313365 14500673 11278835 11546794
SP1 NFKB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18083845 16740634 33572115 7933095
ESR1 BTF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31527615 18025262
IKZF1 IKZF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 9155026 26823144 33961781 10204490
SRPK1 SRRM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25852190 32707033 23602568
SRRM1 SRRM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16159877 9531537 22939629 26344197
SMN1 DDX20 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 11714716 5214807
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
TBP TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HDAC3 YY1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
SF3B4 SRRM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CDC5L CTNNBL1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 MYOD1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ACTB POLR2A â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CD2BP2 DDX23 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
BTF3 RPL10 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ARID2 SMARCE1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREBBP SMAD3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HDAC2 SMARCA4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
HSPA5 SQSTM1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RCHY1 TP53 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EGFR CDC37 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25036637 31980649 12471035 24189400 23956138
CDC5L SRRM1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11101529 20467437 16159877
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
CUL4B EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23238014 24292684 27634302
SMAD3 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15464984 18548003 19917253
HDAC1 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20663877 20022962 15298701 19995069 17369852
EGFR AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
EGFR ARF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 24797263 20029029 31980649
MATR3 DISC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 90000000 31413325 17043677 29961565
MATR3 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27460707 27731383 29884807 26496610
MYC SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11274368 18003922 17418410 15780936 32115405
MYC GSK3B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16247449 11877389 14563837 20713710 19131971 21150319 31638140 8247524 29467282 33541412
MYC CHD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
RRP1B SRSF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23604122 20926688 19710015
TP53 RCHY1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 17568776 5220017
TP53 RCHY1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 17568776 5220017
HDAC2 YY1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
VHL CUL2 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6542648 18323857
SF3A2 DDX46 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12234937 26344197 17332742
HDAC1 MYOD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11285237 11684023 16713569 20124407
SP1 SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11432852 10878024 12228247 22227581 16714330 11114293
DDX17 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15298701 19995069 20663877
HDAC1 CHD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23752268 9804427 20585571 28977666 27068747 26496610 33961781 17827154 22939629 9885572 11784859
EED HDAC2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
HDAC2 CTBP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17967884 31041561 16713569 28947780 16036112 10766745 18212045 11022042
TOB1 SMAD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 11163184
TBP ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9259327 16713569 31527615 11595744
CHD3 IKZF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10204490 30760870 33961781
DDX46 SRPK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26167880 22365833 33961781 23602568 32707033
CHD3 MBD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 28977666 25123934 24981860
SRSF1 U2AF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 26641092 33961781 22939629
SRSF1 SRPK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10196197 12565863 17517895 9472028 23602568
TNIK DISC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 29961565 90000000 31413325 17043677
TOB1 SMAD5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 11163184
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CBX7 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
COPS5 VHL â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDC5L ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
METTL3 WTAP â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
SRPK1 U2AF2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
GABARAPL2 SQSTM1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ABL1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 16273093 25402006 7678409
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
ABL1 DGCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26126715 27182551
ABL1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26603102 25219501
MATR3 AIMP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AIMP2 CHD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AIMP2 ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YWHAG ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
ESR1 CCAR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21596782 20074560 17473282
CDC5L CWC15 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11101529 20467437 20176811 29395067
CDK9 RCHY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23603988
ERCC6 CUL4B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
DDX5 FUS â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
DDX5 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 33742100 12527917
DDX5 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 20308691 11250900 21182205 10409727
EP300 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12527917 20663877
E2F1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18840615
E2F1 MAP1LC3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19657746 18408756
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
SP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10547281 8657141 10850422
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
EGFR HDAC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 24658140 20133936 25402006
YY1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22580610 18391986
EP300 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11268218 16713569 18263614 12937166 24939902 14988403 33742100
EP300 MYOD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20364308 12665587 20037778 17964260 35140242 10944526 9862959 9001254 8621548
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
ERCC6 CUL4A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
IKBKE TRIM25 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
NFKB1 MEN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11526476 16651450 16713569
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
MYC PIN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26655473 29467282 15048125 19131971
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
SMAD1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 15576399 22290435 22761862
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12080043 18414489
MYC RPL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333 11085504
MYC AQR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC PQBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SMARCAD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
SMARCAD1 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21549307 18675275
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
TP53 DDX3X â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24180280 23584477 21325288
RB1CC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16061648 21775823
HDAC1 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18381204 21669397
VCP DERL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 15215856
YBX1 SMAD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12917425 12446674 16278212
YY1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9238849 21852380
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
HDAC1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11929879 16189514 16713569 14988403
CUL4A CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 21249194 22474075 12504025 15448697 18606781 31973889 12609982 27203177 12504026 19295130 16964240 21145461 22405651
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
CUL2 VHL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503656 22086907 28514442 9751722 10823831 15060148 11865071 21942715 27697924 20049704 26743088 11779168 17439941 12604794 9122164 21145461 15611064 19030229 21685897 12048197 10421634 28775317 15601820 10449727 24469044 11384984 10587522 18173839 22286099 17339318 16261165 16611863 23401859 15966899 22234250 9447969 17353931 26751167 18323857 25661653 33137104 11024059 18187417 18523483 10318914 26735018 24981860 33961781 31444342 26846855 17132228
PIN1 SMAD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21988832 19920136 21685363 19122240
PRKCA PIN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
SMN1 ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CALM1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9859994 2550447 19608982
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
MYOD1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10973962 16901893 21689744
AKT1 SMAD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 25241761
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
CTBP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 9650586 16189514 23752268 31041561 16713569 28947780 10995736 34147029 18765668 11022042
CHD4 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25247294 32744500 21258344 11102443 28977666 9885572 26496610 20585571 10220385 22075476 21670149 22939629 23752268 27616479 9790534 9804427 26949739 20693977 33961781 24981860 12920132 26344197
MBD3 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10444591 21258344 11102443 12354758 19041848 27068747 26496610 25123934 24048479 21670149 17827154 22939629 23752268 12124384 16428440 33961781 24981860 26344197
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
HDAC1 SP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15647279 20072153 19062177 11909966 17894944 21636851 18003922 12176973 11896613 15557281 10409740 11517158 15713621 12665570 15722551 17906119 16478997 18850004 16121030 16883603 12091390 15155736 18948152 18059533 16713569 20385359 15528196 16734381 12200149 12847090
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
MBD3 HDAC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 20388487 25123934 19041848 26949739 21258344 24981860 17827154 22939629 12354758 26344197
HDAC2 CHD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12198550 23752268 22939629 9804427 30737378 28977666 26949739 24981860 17827154 12493763 9885572
HDAC2 CHD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 9790534 9804427 11003653 22939629 30737378 28977666 26949739 32744500 21258344 24981860 21670149 12493763 9885572 10545197 26344197
AKAP8 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980585
HDAC3 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12150997 15811852 15494311
HDAC3 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16528103 18241676
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
PRKCA CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11463380 17570479 20577053
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
SP1 PTK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11997104
SP1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20427719 20538607 9151857
AKT1 GSK3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19713527 8524413 23824745 16009706 29464284 20856200 19995607 16123141 20682768 27563096 14645548 15688030 22337773 11035810 17428466 18505846 15470047 14701753 16282323
PRKCA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19836308
SRSF1 NXF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15210956 22658674 21988832 18596238 15184380 34133714
CHD3 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CTNNB1 CHD8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10921920 10944533 18378692
ESR1 DDX17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 11250900 21182205 20348541
SUZ12 EED â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
EED MAP1LC3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IKZF1 CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IKZF1 CTBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21900206 16189514 25416956 16713569 10766745 24722188 27107012
IKZF1 IKZF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17383641
CTCF HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
MBD3 CHD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25123934 25247294 28977666 32744500 24981860 21670149 22939629 12354758
EZH2 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EZH2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21135039 21884980 27338022 18931660 28068325 23079660 24469040 19026780 21190999 26496610 26748827 24320048 33849069 35016035 27634302 29669287 18285464 20543829 18453536 31130994 21123648 20123894 24183680 27728805 25470042 12435631 22939629 16224021 23624935 24457600 26344197 20075857 15882624 23684459 31786184 31281901 23238014 26130719 19026781 27705803 22439931 27303043 31631027 24981860 33961781 19734898 31948940 18483221 21378168
CTBP1 CHD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
U2AF2 SRPK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16189514 16713569 33961781 9472028 23602568 32707033
SRPK1 DGCR8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 23602568
SF1 FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9660765 16713569
SRPK2 SRRM1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 26167880 33961781 23602568
WBP11 PQBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25416956 16713569 27314904 10593949 33961781 11054566 26344197
CTCF SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18662993 21536749 33196849
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
GABARAP SQSTM1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
VCP DERL1 â—¼   PHYSICAL_INTERACTION ✅ + 0.9 0.9 Signor 15215856
CWC22 SRRM2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
SRPK1 SRSF1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
DDX17 FUS â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ACTB CDC37 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
SF3A2 U2AF2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
HDAC2 SUZ12 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CRNKL1 SRRM2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
ACTB SMARCE1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
CWC27 SF3A2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CWC22 SF3A2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CWC27 SF3B4 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
AQR CWC15 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CDC40 CWC27 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CWC15 CWC27 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CDC37 CDK9 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
EZH2 EED â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
EED HDAC1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
SRPK2 U2AF2 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
RANBP9 RMND5A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CHD3 HDAC2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CHD4 MBD3 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
BCAS2 SF3A2 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
SF3A2 SRRM1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
SF3B4 SNRPC â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CREBBP CTNNB1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CTNNBL1 CWC15 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
AKT1 ARRB2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 18191226 19122674 19262695
CDK9 POLR2A â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
AQR SF3A2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ARID1B SMARCE1 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
ERCC6 POLR2A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
SF3A2 YY1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
AIMP2 BCAS2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
DDX23 SF3A2 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
NCBP1 SNRPC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CRNKL1 CWC15 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CDC40 SRRM2 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CTNNB1 TCF4 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CWC15 CWC22 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CWC22 CWC27 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AQR CRNKL1 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MAP1LC3B SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MAP1LC3A SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
BCAS2 SF3B4 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CHD3 HDAC1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CWC22 SF3B4 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
AKT1 GSK3B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
SRRM1 SRSF1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CHD4 HDAC2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
SRRM1 SRRM2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CWC15 SRRM2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
TCF4 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219694 17318191
AKT1 STK4 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 19940129 17932490
AGO1 DICER1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CDC5L DDX3X â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ALYREF DDX39B â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CALM1 DAPK1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CHD4 HDAC1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
NCBP1 SART1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
AQR BCAS2 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
SF3A2 SRRM2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
BCAS2 CWC15 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
CDC40 RNF113A â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
SQSTM1 MAP1LC3A â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 19427866 7034152
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
CDC5L SF1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CRNKL1 SART1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ACTL6A ARID1A â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
PCNA TOP1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CDC5L RNF113A â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
DDX23 SNRPC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
ARID1B SMARCA4 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
DDX17 DDX5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22365833 15298701 19995069 22863883 33961781 24581491 10837141 22939629
E2F1 SP1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10850422 10409740 8657141 10547281 8657142
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
NCBP2 NCBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
CTBP1 ZEB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 17967884 31041561 34462429 25086746 33961781 10567582 26186194 35016035 10359772
EZH2 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 21685935 15520282 10581039 24771265 31130994 22439931 26344197
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
RYBP RNF2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CDC5L SRRM2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
CWC15 SF3B4 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
POLR2A SMARCA4 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
SF3A2 SNRPC â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
DDX20 SMN1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MAEA RMND5A â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CWC15 SF3A2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CRNKL1 CWC22 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
HDAC2 MBD3 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CDC40 SF3B4 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
NCBP2 NCBP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 23665581 9933612 26382858 31467278 11545740 22365833 26496610 29395067 12374755 26264872 7478990 19668212 22939629 29997244 32814053 29101316 24981860 31448526 17190602 12434151 26344197
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
EED HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10581039 11124122 26496610 22439931
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
EED HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30737378 10581039 11124122 24981860 24457600
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
CTNNB1 GSK3B â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
EED SUZ12 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 29379173 27338022 19026780 26496610 35016035 27634302 15385962 15225548 18285464 20543829 12435631 31786184 24457600 31281901 20075857 19026781 21078963 27705803 22439931 28320739 33961781 24981860 23280602 18483221
EED EZH2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21135039 9584197 9742080 31948940 29379173 27338022 18931660 28068325 33754075 11158321 9584199 32296183 22897849 17937919 19026780 21190999 26496610 24320048 33849069 27634302 15385962 16314526 29669287 15225548 18285464 10581039 21123648 12435631 31786184 23624935 24457600 20075857 15882624 19026781 21078963 22094255 22439931 28320739 27705803 31527584 24981860 33961781 23280602 26344197
MAEA RANBP9 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
SMARCAD1 TRIM28 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PCNA SPRTN â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CDC40 SF3A2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CDC40 CWC22 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ACTL6A SMARCE1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CDC5L SRRM1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ACTB SMARCA4 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DDX46 SF3A2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CDC5L U2AF2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HDAC1 MBD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
DERL1 VCP â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
DDX23 SART1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
ARID2 SMARCA4 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
POLR2A TBP â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
BUB3 ZNF207 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CBX7 RNF2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
SART1 SF3B4 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
AQR CDC40 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CDC5L CWC27 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
BCAS2 CDC40 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CDC40 CWC15 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ARID1A SMARCE1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
AQR CDC5L â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CDC5L CWC22 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CDC40 CDC5L â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SF3A2 SF3B4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ARID1A SMARCA4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ACTL6A SMARCA4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC5L CRNKL1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC5L CWC15 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC5L SF3A2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NCBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC40 CRNKL1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCA4 SMARCE1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SART1 SF3A2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SF1 U2AF2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EED SUZ12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
BCAS2 CDC5L â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RYBP ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 8943360
ABL1 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17018282 17412694 11823473 17384675
ABL1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12415271 21212806 26998525 20841568
ABL1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15448168 20841568
ABL1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26721416 27618557 24868554 21715626 30903103 22590567
ABL1 ERCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17626041 20841568 27827925
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16099633 25164010 17618275 24465953 20841568 17318191 20840866
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
YWHAG ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17353931 15324660
CDK9 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
CDK9 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
CDK9 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 22053051 20222012 25023704 14662762 10364292 20106982 18066052 30135578 24385927 18644870 18329373 14517250 20932174 12052871 20226668 19575011 8416977 11575923 16735508
CDK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24173284 9372954 11483158 9315650 19413330 19664995 23603988 24202322 11709713 16083285 1088347 16552184 10884347 24286312 10747897 17942552 16741955 17287340 92065884 12064478 10348343 14702041
AKT1 CLK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20682768
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
AKT1 COPS6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26318036 23095642
PCNA CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PRKCA DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 7525583
DDX5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24219989 15660129 20876186 19626115
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
TP53 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21715977 20805247 8557038 11795482 17210690 22952705
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
SP1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9054613 12697671 10446910 18440323
E2F1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7623816 12782299 14618416 20580656 9389735 11133765 8903355 9649317 23078099 12468739 1261188
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
E2F1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22241525 8557038 15706352 21441950 12675512 23954287 12625370
CREBBP E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10753885 15126619 12748276 15123636 8932363
E2F1 EED â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18319725 14532106
E2F1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15510213 18319725 11491305
E2F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22480684 11739724 12625370
E2F1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18319725 14532106
E2F1 HNRNPA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19541929 17001603
YBX1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19036157 17595327 24211838 19648825 17875215 16651443
NFKB1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14678988 18367518 12469217 17881446
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
PRKCA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 11447289 8321321 11313945 25402006 12040186 20888375 15302935 6321473 1860884 12878187 6090944 19568798 14585353 17496910 21386996 24658140 2984676 11940581 31980649 15212693 85012702 19615955 2987962 12845332 3379075 7805884 10816576 15567848 16488589
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EGFR CALM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17145710 19901323 20029029 12359306 16497976 25402006 17389395 18578522 16799092 20068231 3415247 7925415 18669648 12153558 24658140 17287340 14960328 18707149 17016520
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 21220489 24655521 23542172 29140271 28157503 26725162 22238610 25825764 17115032 26719139 28102297 22692198 28666590 25073158 20670598 20587074 23593472 25675097
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
EP300 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944526 9001254
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
ERCC6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16713569 10882116 19221478 18784753
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
MAPKAPK2 PIAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24705157 23202365
MEN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
MEN1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11526476 16997566 16713569
NCBP2 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP1 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
MYC PIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC PIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
TCF4 MYC â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10391247 11955436 11967263 12051714 15001769 15082531 15576399 16039586 17143292 17936032 19619488 20705860 22290435 22761862 23343194 24023259 25730849 7542250 8666229
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
TCF4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21533051 19778454 15928669 20133699 18852287 19561604 19662654
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
TBP MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20886042 7880838 9797456 15876353 14506152
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
MYC SRSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12747840 22545246 23935626 18414489
MYC NDRG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11936845 18455888 10381566 21976667
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
GSK3B MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 17081983 18463697 21646472 30037819 26751215 25647305 2663470 20080742 19797085 30003124 16855632 12040186 18679417 11018017 23331499 29229669 16611981 21071413 24265759 20068231 10671551 16039586 17570479 16023596 29258530 12615961 18669648 21113395 22461507 19131971 8247524 16247449 20604938 19575820 15150404 22481935 23668310 19651622 17444818 23964270 20537194 22893788 27684546 24662831 25333250 20399964 11877389 14563837 18408012 17052453 18455992 15212693 16371461 11274345
PIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26655473 15048125 30723410 23716601
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
TCF4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
TP53 NDRG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15377670 11237058 18431400 17442733
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
SMARCA4 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11532957 14964309
SQSTM1 CUL3 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 14744430 15340068 16252010 18545270 19427028 20531300 21981924 25002027 26587781 28574505
SP1 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9762895 12736330 17012241
GABARAPL1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17580304 20562859 23022382 21691068 25416956 31053714 16189514 32296183 21617041 19250911
MAP1LC3A SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 20061800 23022382 23459205 35044719 22963397 36036324 31053714 21045561 25921531 19250911 17580304 21628531 20204693 28740232 23640897 25686248 24100292 26075355 20562859 22658522 25984893 21460636 16286508 19427866 32296183 23989536 19021777 26268733 22714671 24998849 18653543 31366950 33436498 16169070 23239879 26754771
GABARAPL2 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17580304 20562859 23022382 17353931 24582747 25416956 33436498 31053714 16189514 32296183 21460636 19250911 21900206
MAP1LC3B SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 18083104 23022382 35044719 26413874 25416956 22434781 31053714 24023838 19250911 17580304 23333919 20452972 24668264 28085563 21900206 20562859 20010802 25007327 32296183 33302793 24582747 33436498 16169070
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TP53 MGMT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17564708 19846904 19056673 9780001 18555750 8616846 21957016 17234766 12503076 20525765 19531487
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
DAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 15355354 17297916 32266931 26626260 27753536 15254178 27681874 22112863 10734067 11883897 21386980 22815859 20851891 11244509 10733583 15542844 26742101 10673501 12091386 18246126 25584963 15489221 20959462 11258706 10801407 10606744 11707453 17339337 12111733 17977830 25229255 34168813
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
RCHY1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 21988832 19483087 17568776 24367557 25116336 21084285 12654245 21791603 20452352 19043414 16713569 31630802 27519799 19918835
PIAS1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 15133049 10380882 20805487 11867732 16713569 11583632 11788578
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PIN1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12397362 12388558 17906639 12397361 21741598 16713569 24982848 21900206
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
PRKCA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18812399 9935181 15659650 9315650 19933256 16713569 9571186 1454855
PPP1CA TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20424263
TRIM28 CHD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18082607 11230151 24018422 16169070 21642969
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
AKT1 VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16551632 19335618 16027165
AKT1 YBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17081983 32028981 33911076 26318844 33151228 20844753 27591085 17704806 21423216 19036157 31906126 15806160 24335958 34272387 33379356 19651622 31387591 16354698 19664994
NFKB1 YY1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17438126 21725609 23178297 23572150
YY1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16452489 15899857 15760841 8972185
HDAC2 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9016636 19139378 11486036 8917507
HDAC3 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11486036 9346952 17925399 16189514 18940814
PCNA CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
CUL2 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
CUL2 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
DAPK1 PIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 24853415 25849135 27618008 21497122 21852138 26387736 29665256 25766872 23633483
PIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 11533658
CALM1 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11313698 9367156 20103772 15048887
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
NCBP1 WTAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP1 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
MYOD1 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10082523 1662816 9148896
CREBBP MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10944526 16713569 11463815 9238849 2176177
PRKCA MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17570479 11025438 1335366
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
SMAD3 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 ZEB1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 14976548 15265520 16179589 16713975 16831886 18768831 18832382 19208835 19597490 20731704 21042762 21317430 21614932 22331441 8515656 8893010 9389648
CUL1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11359933
AKT1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 25241761 15104092 16362038 21071413 18988627 26297431 15048128
GSK3B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 18172167 21071413 21310903 23077590 28756206 19114991 19002158
CREBBP SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15849193 10497242 15467747 18003620 9679056 15990875 15750622 19589780 17074756 17283070 9679060
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
ZEB1 SOX2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC3 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC3 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC3 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
NFKB1 CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
CTNNB1 CREBBP â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
SP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23297421 20096088 9765204 21191649 21464950 12200429 20130956 12169688 15576380 15184875 15713621 18571793
CREBBP CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10769018 21751375 11973335 17410209 18347063 16476742 23273993
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
TCF4 SMAD1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10391247 11955436 11967263 12051714 15001769 15082531 15576399 16039586 17143292 17936032 19619488 20705860 22290435 22761862 23343194 24023259 25730849 7542250 8666229
TCF4 SMAD1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10391247 11955436 11967263 12051714 15001769 15082531 15576399 16039586 17143292 17936032 19619488 20705860 22290435 22761862 23343194 24023259 25730849 7542250 8666229
CTNNB1 TCF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12086873 11943708 13679048 15806138
CTNNB1 TCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 24532795 11713475 18281465 25402006 16724116 12799378 12944908 12727872 23331499 15060161 17412698 22080605 21743491 17875931 12657632 17983804 20126258 17318191 24798214 24876153 29361949 17909039 23449499 22699938 18595660 9308964 16007074 15331612 11713476 15665104 17072306 15525529 17962194
PRKCA ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22521536 17570479 17420447
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
ILK GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15207235 14990992 16799642 20827300 27683053 9736715 12960424 26547035 17490631 12629168 17182785 21035499 16189514 17107957 16936772 17485554
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
PTK6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20606012 15994200 15539407
PPP1CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 SRPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19592491
AKT1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22391560 24526064 29864144 34230470 16224021 26517694
AKT1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 99.0 1.0 Omnipath 17428466 15207235 17145710 12052830 10729337 8250835 11756412 11923280 16914735 17623045 16697215 8524413 12054501 20398329 18372248 21506126 20028971 12040186 15808505 16543730 20138985 23331499 21303971 16009706 10385618 20214616 23180781 9373175 16039586 15829723 18988627 16282323 11577096 11035810 18669648 18216173 15169778 12851486 16123141 11882383 23109003 9065430 18691976 22094462 10949026 22710759 11715018 12459251 18636226 17192257 11254732 11278246 20858269 9812896 9582355 15023346 17680028 19369195 7945242 12900420 23552696 18387957 10722653 20832730 18570873 12147701 18505846 17052453 17693255 18218901
AKT1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 22619175 19369195 19737514 19940129 17932490 23431053 11805089 24872389 23893242 17726016
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 ALYREF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18562279
NFKB1 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20966071 22708120 16317091 16271621 10833420 10496926 16249517 7536741 19281832 10553096 19422386 7537851 16385502 10946302 16453001 10329958 11359843
GSK3B NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 26999213 12871932 11425860 24618402 18669648 17693123
PRKCA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 92316961 15212693 26888287 1377674
PIAS1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15666801 11117529
GSK3B SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 18045539 25241761
CTCF CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19129223 22422629
GSK3B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 183.0 1.0 Omnipath 22415718 11967263 27158593 29455668 19303846 19797085 8638126 19293931 23056571 22662165 25352148 16611981 27068260 28337019 10671551 21743491 20688898 16293724 23721711 23552738 18687691 28977889 19622173 12051714 25241761 27683053 28549350 22699938 19565571 23076981 21562161 19575820 20219694 20537194 10330181 21986938 29183346 27773936 11251183 19711366 21035499 19675674 7542250 23151663 24451375 14663202 23804296 8524413 25639486 23770025 18070361 26892600 30143633 9233789 19667122 27507058 19061640 19223551 29387014 23331499 16199882 11533658 18644116 24501426 24913829 11835406 17318191 26014148 25366337 28183999 22640743 26910375 12000790 12114015 18387957 19107203 9832503 16371461 29805709 27462866 20137080 27902311 12040186 19576224 25644994 12615961 19060929 25897075 12851486 15465828 17053159 18952601 10228155 15020233 17444818 20140245 26453498 17052453 16944320 24015932 23602568 24975844 24931005 28948000 20080742 23209942 30271168 28220106 16520547 28430641 11818547 25546293 27672271 11955436 11154277 26373837 16039586 23778311 28697793 20302655 25136145 26905812 22216350 8666229 12957350 23109003 10074433 28529629 20215423 21329734 11254732 9501208 27098453 27281614 30279527 19631635 25482131 18455992 24403311 11274345
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
CHD8 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18378692 15367660 11744694
DDX17 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19995069 21182205 12738788 20348541 19718048 20663877 25604459
EED CTCF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17851529 17761849 25135475 17185360
EED EZH2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
NCBP2 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP2 WTAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
SRPK1 SRSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 8798720 18155240 8208298 23602568 10390541 9472028 17517895 10196197 12565863 21045158 24449914
SRPK2 ACIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21056976 23602568 18559500 22365833 17287340 19592491
SRPK2 SRSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23602568 9472028 16189514 10196197
RNF2 RYBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105