Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PRMT5 H3-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
ATM DYRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19965871
XRN2 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ELOC CUL2 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 5219492 17183367
MYC H2BC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
PRMT5 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1209814109 23071334
H4C6 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18079182 11448779
H4C6 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 PRMT5 â—¼   METHYLATION ✅ 2.0 0.8 intact 1209814109 23071334
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
HDAC2 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
HNRNPD ACTR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17006931 8076602
PRKDC ANXA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATM CCAR2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 22465953 22735644
BAG2 WDR77 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
BAG2 CCAR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
CCT5 BAG3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EEF1A1 BRMS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
C1QBP HNRNPF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA8 CCAR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PRMT5 CCAR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PRMT5 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT3 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
MYC CCT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
HDAC2 COL14A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MAPK14 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18806262
TARDBP DDX3X â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF4B DDX3X â—¼   COLOCALIZATION 2.0 0.8 intact 8407815 22872150
TARDBP DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC DDX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
SMAD3 DGCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21102523
SMAD2 DGCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21102523
HSP90AA1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
DNAJA1 STIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
HSP90AA1 DNAJA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
DNAJC7 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
HSPA5 DSP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EEF1A1 DYNLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EEF1A1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
EIF3M EIF3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18599441 0801313105
MYC EIF3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
EIF3M EIF3H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18599441 0801313105
EIF4A3 EIF4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPK EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16024782
EIF4E SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12150994 23331499
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
TXN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19737086
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
FASN EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PCBP1 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
EWSR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8164678 11423975
HSP90AA1 FASN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
VIM FUBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PUF60 FUBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PRMT1 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TARDBP FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FUS MATR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27731383
TXN GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NPM1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219698 17318229
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
HNRNPF HNRNPD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PTBP1 HNRNPD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
TARDBP HNRNPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TARDBP HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SYNCRIP HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
MATR3 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HNRNPK PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HNRNPK PRMT1 â—¼   METHYLATION ✅ 2.0 0.8 intact 6803829 19101556
HNRNPK MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8349701
HNRNPM WDR77 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPM SRSF2 â—¼   COLOCALIZATION 2.0 0.8 intact 7945687 20467437
PRMT1 HNRNPR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TXN HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC HSPA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
HTATSF1 SNRPD3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HTATSF1 SF3B2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
KRT18 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STUB1 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
MAPK1 METTL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 33217317
MAPK3 PCBP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17475908
MAPK3 METTL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 33217317
TARDBP MATR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MATR3 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
MPP1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MYC MSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12808131 11983916
TARDBP MYC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC STIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC RPL23 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14519204 11085504
MYC SNRPD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
PUF60 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20420426
PTBP1 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218180 16376875
UBC NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6541703 18259216
PUF60 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PCBP2 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PTBP1 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SF3B2 PCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
WDR77 PCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SNRNP70 PRMT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
VCP PSMC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMC5 PSMC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PSMC6 PSMC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16763564 5218720
VIM PUF60 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SYNCRIP RPL24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMAD2 RPS14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNRNP200 SF3B2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
VIM SIRT6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SNRNP70 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBC SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
UBR5 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNRNP70 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8308197 22045334
SMAD3 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SRSF2 SNRNP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 8261509
SNRPD3 SNRPB â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 22365833 8293266
TRIM28 TBL1XR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11013263
VIM TRIM28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM TUBA1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
TUBA1C VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
UBC USP5 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
UBC USP5 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 7851534
VIM WEE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT2 CCT4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
EIF3B EIF3H â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
NONO NUDT21 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PSMC4 PSMC6 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DDX5 SYNCRIP â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
ATM TUBB2A â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
HNRNPM U2AF2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SF3B2 U2AF2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
METTL14 METTL3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPA3 HNRNPD â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
DNAJB1 HSPH1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
RPL24 RPS26 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DDB1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24249678 26679995 25189618 34026424
FUS SFPQ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
NUDT21 TARDBP â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SEL1L VCP â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
SFPQ SNRNP70 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPD HNRNPF â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
HNRNPA3 HNRNPK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CCT2 TCP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MATR3 TARDBP â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HTATSF1 SNRPB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
BRMS1 HDAC2 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
TUBB2A TUBB4B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
HNRNPM TARDBP â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MYC XRN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
ANXA1 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21900206 30585729
CDK9 ANXA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 9184228 26209609
MYC ANXA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 30081903
ATM HUWE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17478428 22213803
BAG3 MLF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 26496610
CDK9 PCBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17643375 27684187
ESR1 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20308691 19805454 21182205 20348541
LMNA DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25948554 22412018
DDX5 U2AF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26641092 22939629
EIF3H RPS14 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
MYC EIF3I â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
EIF3M RPS14 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
ESR1 MSH6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
ESR1 HUWE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
U2AF2 FUBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26641092 32296183
HDAC2 FUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
GTF2I XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30585729 26344197
MYC ILF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
PCBP1 MATR3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 16713569
MYC MATR3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MCM3 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
XRCC6 MSH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 21075794
MYC PRKDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC SF3B2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC PCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC NSUN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RBM15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 29467282
MYC U2AF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC PTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
PRDX2 PCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 26344197
PSMC3 PSMC4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SRSF2 U2AF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26641092 22939629
U2AF2 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26641092 30585729
DNAJA2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
EIF3H RPS26 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
EIF3M RPS26 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ESR1 STUB1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
SFPQ TARDBP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DNAJB1 DNAJB4 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
TUBB2A TUBB4B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SFPQ WTAP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SNRNP70 U2AF2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPM MATR3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CBLL1 WTAP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
FUS SYNCRIP â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
NONO TARDBP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
AMBRA1 DDB1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CDK9 DDX5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17643375 26209609
MATR3 DDX3X â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29884807 26496610 29511296
MATR3 DDX5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29884807 26496610 29511296
ESR1 EIF3B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30573685 31527615 19805454
EIF3J EIF3I â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 14688252 26186194 33961781
LMNA FUS â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25192599 22412018 25948554
FUS NONO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25192599 22939629 26344197
STUB1 HSPA8 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16293251 5218068
MATR3 ILF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29884807 26496610 29511296
MYC LMNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
MATR3 PTBP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29884807 26496610 29511296
MYC NONO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 29467282 17314511 17967896
NONO U2AF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26641092 21566083 26344197
SFPQ U2AF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26641092 22939629 21566083
FUS PRMT1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HNRNPF HNRNPH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
PRPF31 SNRNP70 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HDAC1 SFPQ â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KRT1 KRT14 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
HNRNPA3 SF3B2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
DDX3X FUS â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
DNAJA2 HSPA4 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
EEF1A1 RPL23 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
EIF3H EIF3M â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
NONO SFPQ â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HDAC1 SMAD2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KRT10 KRT5 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KRT2 KRT5 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
DNAJA2 STIP1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
PSMC5 VCP â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SF3B2 SFPQ â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
MYC ACTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29467282 11839798
EEF1A1 RPS26 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ESR1 SRSF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 21182205
ESR1 GNL3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 21182205
FUS ILF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27460707 29884807
DDX5 ESR1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
EEF1A1 RPL38 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DNAJB4 HSPH1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
DNAJB4 HSPA4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF4A3 SNRNP200 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ATM ANXA2 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
CCT3 CCT5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
TUBA4A TUBB2A â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
HNRNPM NONO â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
SF3B2 SNRNP70 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
DDX3X EIF3H â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
KRT18 KRT6A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
SF3B2 SNRNP70 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPK HNRNPM â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CCT5 CCT7 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPR PRMT1 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
DDB2 PRMT1 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
SMAD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11555647 20207742
ESR1 NONO â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33731348 25604459 31527615 20348541
ESR1 RBBP7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23403292 31527615 18577416 21182205
SMAD2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31130994 10199400 14699069 11226163
U2AF2 SF3B2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26641092 28514442 33961781 27720643
CCT5 CCT8 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EIF4A3 SNRPD3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
EIF4A3 SNRPB â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
PSMC3 VCP â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
PSMC6 VCP â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
PSMD13 VCP â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
HNRNPK SFPQ â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
TUBA4A TUBB â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
MATR3 NONO â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPM SFPQ â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
DDB2 RPS14 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
CCT2 CCT3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
FUS HNRNPR â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
ATM PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10464290 10608806
EIF3I ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 10706629
MYC HUWE1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16269333 31677785 29467282 26279298 17314511 18488021
DDX3X EIF3B â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
HSPA9 HSPD1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
HNRNPD HNRNPU â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
DDB2 TUBAL3 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
SNRNP200 SNRNP70 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
USP5 UBC â—¼   CLEAVAGE ✅ + 0.86 0.86 Signor 26235645
CCT2 CCT7 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PSMC4 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PSMC6 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
HDAC1 RUVBL2 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
HNRNPH1 SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ESR1 ACTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20308691 19805454 21182205 21182203 31527615 20348541
DNAJB1 HSPA4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MYC GNL3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 29467282 17353931
HDAC2 GTF2I â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12393887 30737378 12493763
MYC HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 17314511 30415952 20195357
KRT10 KRT2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
LMNA NONO â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25948554 22939629 22412018
MYC UBC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 16996503 19131971
PRPF31 RUVBL1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EIF3B RPS14 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3B RPS26 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3I RPS26 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3J RPS26 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
KRT1 KRT2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HNRNPA3 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CCT2 CCT8 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
EIF3B EIF4E â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PSMC4 VCP â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EIF3J RPS14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HNRNPD PTBP1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TUBB TUBB2A â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CUL2 PRAME â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
HSPA4 STIP1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
PRAME ELOB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21822215 23460923 31253590 22912744
PRAME ELOC â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21822215 23460923 22912744
BAG1 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8524784 15538384 18388150
MYC CDK9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17700062 12944920 30415952 26687678 19818711 11673469
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DSG1 DSC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19136012 24981860 9606214
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
SFPQ FUS â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 15975576 25192599
KIAA1429 ZC3H13 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
PCBP1 PTBP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27684187 16713569 26344197
PCBP1 PCBP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23640898 27684187 16713569 26344197
DNAJA2 HSPA8 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ESR1 HSPA4 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PUF60 U2AF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TUBB TUBB2A â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
BAG1 HSPA4 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HSPA8 HSPH1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
BAG1 STUB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DNAJA1 HSPA8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HNRNPU SYNCRIP â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DDX3X EIF4E â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
EIF3I RPS14 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
PRAME CUL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23460923 33961781 22912744 21145461 26186194 21822215 28514442
MLF2 BAG2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25036637 17353931
HDAC1 DDX5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19995069 20022962 17369852 15298701 20663877
SMAD3 DDX5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18548003 15464984 19917253
MATR3 FUS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29884807 27731383 27460707 26496610
ILF2 PRKDC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9442054 17389650 20808282
XRCC6 MSH6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30585729 22863883 21075794
MYC MSH6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17314511 29467282 17353931
MYC XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282
PCBP2 PTBP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10772858 16189514 16713569
CDKN2A NPM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
EIF3J EIF3M â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
LSM4 SNRNP70 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
LMNA TMPO â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
NONO SFPQ â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
METTL3 WTAP â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
KRT16 KRT5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
HSPA8 HSPBP1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
DDX5 FUS â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PSMC5 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CUL2 ELOB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11384984 9122164 30166453 24981860 21145461 12048197 19327355 24076655 15601820 18173839 31253590 25661653 15966899 12149480
IGHG2 C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
ACTC1 GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
XRCC6 ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CCT7 ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GAPDH ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA1 ANXA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ATM METTL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 32615088 17525332
IGHG1 C4A â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 15199963 14280442 12396008
ESR1 CCAR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21596782 20074560 17473282
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
DDX5 PRMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14631847 28539435 14675539
MYC EIF4B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
ESR1 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28539435 18657504 11029009
ESR1 NFIB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26153859 18414489
MYC FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14519204 12695333
PUF60 FUBP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20711187 10882074 32296183 29997244
MYC GAPDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC GNL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
GTF2I MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17314511 30415952 8377829 29467282
MAPK1 GTF2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10648599
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18381204 21669397
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
HDAC1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10199400
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
VIM HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 MAPK8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MAPK1 PCBP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17475908
MAPK8 RBM15 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC MSH2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29467282 30415952 28205554 17314511 28628118 12584560
SMAD2 MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28205554 11804592 28628118
MYC PRKDC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PTBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20010808
MYC SNRPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC THRAP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 12808131
SFPQ NONO â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 34017080 11259580 24981860 26344197 22939629 25959826 18042045 31815296 12403470 30725116 21988832 17507659 28514442 30445466 17452459 30021884
TXN PRDX2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 21385867 10514471 17519234
XRCC6 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8422676 20711232 19303849 26175416 28345663 30585729 17308091 22939629 26496610 10750018 15941674 33005030 21969602 15520013 10064605 21575865 26446488
PRKDC VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16140914
SFPQ PTBP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8449401 15975576 17507659 16713569 10653975 11514619
U2AF2 PUF60 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32296183 26344197 17353931 22365833 22939629 10866799 16169070 16713569 25416956 16189514
VCP SEL1L â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21357747 23867461 19002207
BRMS1 HDAC1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PSMC1 UBC â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
EEF1A1 RPL24 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CCT4 CCT8 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
LSM4 SF3B2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
NDUFAB1 PSMC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRPF31 SF3B2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
KRT1 KRT16 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT16 KRT2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PSMC1 VCP â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
CCT3 CCT4 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
EEF1A1 RPS14 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
KRT16 KRT6A â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PSMC3 PSMC6 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
BAG3 HSPA4 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CBLL1 WTAP â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
BAG3 HSPA8 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PSMC3 UBC â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
PSMC3 PSMC6 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
MSH2 MSH6 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
CCT4 TCP1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
EIF3H EIF3J â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATM ACAT1 â—¼   KO_UP_REGULATES ✅ + 0.92 0.92 PKG 28854368
ACTB RUVBL2 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
STIP1 HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ - 0.92 0.92 Signor 27353360
WTAP ZC3H13 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PUF60 SNRPD3 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
UBC VCP â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CCT4 CCT7 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT7 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT8 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
ACTB RUVBL1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
UBC UBR5 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
CCT3 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
U2AF2 C1QBP â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 28514442 32877691
CCT3 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
HSPA8 STUB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CCT7 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
HSPD1 PUF60 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
CBLL1 KIAA1429 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
SF3B2 SNRPB â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
CCT2 CCT5 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
CCT3 CCT7 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
BAG2 HSPA8 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
LSM4 PRPF31 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
LSM4 SNRPB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PRPF31 SNRPB â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
EIF3H EIF3B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 18628297 24981860 26344197 19615732 22939629 18599441 32269044 26186194 28514442
EIF3I EIF3J â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CUL2 ELOC â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11384984 9122164 10449727 31444342 30166453 21145461 23563313 26735018 24981860 19327355 24076655 29991678 15601820 19339690 17183367 9447969 25661653 15966899
ELOC ELOB â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 20211142 29401731 30166453 24981860 10205047 17997974 22939629 17922844 21516116 21822215 22863883 31253590 9447969 7660129 23333304 26344197 16675548 23988114 11739384 12149480 32296183 24402281 25416956 19159283 16189514 10224134 10449727 12050673 31444342 10587522 12004076
RBBP7 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 17255935 22939629 26496610 11102443 27705803 9885572 10471499 26344197 21258344 12920132 9790534 19686092 9150135 28514442 25885317 10444591 19703393 15451426 26186194 23752268
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
KIAA1429 WTAP â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
KRT1 KRT10 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
KRT14 KRT5 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HUWE1 UBC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
FUBP1 PUF60 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
HSP90AA1 STIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
SF3B2 SNRNP200 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PRMT5 WDR77 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
SNRNP200 SNRPB â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
LSM4 SNRPD3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
UBC USP5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
EEF2 RPS14 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
EEF2 RPL38 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPL24 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPS26 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
PRPF31 SNRPD3 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
BAG1 HSPA8 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
LSM4 SNRNP200 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
EEF2 RPL23 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
HSPA8 STIP1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
MSH6 MSH2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 9428522 15064730 26344197 8942985 10748159 22939629 25241761 26496610 14657349 10856833 9774676 10783165 10029069 19377479
SF3B2 SNRPD3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
SNRNP70 SNRPB â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PSMC1 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMC3 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMC4 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMC5 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMC6 PSMD13 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
DDB2 ANXA2 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
SNRNP70 SNRPD3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HSPA4 STUB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3B EIF3J â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPL38 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL38 RPS26 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SNRPB SNRPD3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3H EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3I EIF3M â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PRPF31 SNRNP200 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC3 PSMC5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMC4 PSMC5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL24 RPL38 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL24 RPS14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL38 RPS14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SNRNP200 SNRPD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3B EIF3H â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3B EIF3I â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC1 PSMC4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC1 PSMC3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC1 PSMC5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC3 PSMC4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC4 PSMC6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC5 PSMC6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPL24 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL24 RPS26 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RUVBL1 RUVBL2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3B EIF3M â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3H EIF3M â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMC1 PSMC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS14 RPS26 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MYC CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7739536 10931841 11673469 10657901 12177005 14519204 9111322 9811896 10567564 17706770 24771621 11983916
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
MAPK3 CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17206380 25472841 12438317 15890648
MAPK1 CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10659854 12438317 15890648
XRCC6 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H4C6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
PRMT5 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19234465 29227283 15670829 20951943 23071334
DYNLL1 AMBRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 27173435 20921139
XRCC6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MSH2 ATM â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
MSH6 ATM â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
ATM MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15210935 17244605 30062004
ATM TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 25128619 22496453 34194047 30323812 26158765 16862143 28607002 19584288 20858735 28851455 18285803 34419074 17833484 22491012 25404613 21642969 28439615 27364555 27602502 26671524 23096706 23935532 28739276 24754998 25905708 28847822 24461736 23318425 23346550 17178852 27432546 27820601 17942393 21868291 32060145 22205726 25846574 26293668 25533843 23034801 23352131 28249048 23633913 17525332 18657500 24794298 23645696 26212333 23050241 22715096 27376578 23370278 24657165 29540829 25173936 19071136 28847828 20424263 34518220 25956864 23554604
ATM KHSRP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17525332 21329876
ATM CCAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26158765 23357756 26194823 27503537 22735644 24567900 17525332
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
BAG1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 25535373 26871637 9305631 11222862 10671488 14978028 17954934 20675402 25416956 9873016 19800331 16189514 9774640 12874020 11741305 12297498 27474739
BAG2 STUB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16169850 16207813 25036637
BAG3 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 25036637 27474740 23824909 21233200 9873016 26496610 16189514 21423662
CDK9 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
NPM1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16957780 20208519 15289458 16199867 16915296
PSMC3 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18805416 17334400 14665636 16713569
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
CDKN2A HUWE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 16915296 15989956
POLD1 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
DDB1 DDB2 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 DDB2 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB2 DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 54.0 1.0 Omnipath 9418871 17145710 16751180 27203177 22118460 17041588 20368362 18593899 16964240 12050362 19295130 22039351 11564863 16473935 16678110 17392787 24249678 19109893 12151405 26186194 12812979 16949367 18936169 22822215 14751237 10777491 26410533 16260596 19966799 17360488 12732143
DDX3X EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18596238 21883093 17667941 22872150
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
HSPA8 DNAJA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20084477 20809635 24012426 7828728 20072699
DNAJC7 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19875381 20661446 12853476 15189447
MYC EIF4E â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18593934 15094771 8756633 12695333 24814906 14519204 22456335 16112647
MYC EIF4E â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18593934 16915296
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 KRT14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20188517 19435901 23870655 20578288
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 LTF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16861234 8873065 10738912 10779508 15525592 8441416
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
PUF60 FUBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10882074 20420426 20711187 11239393
FUBP1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15502847 2191300 18490439 19219071
PRMT1 FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 30354839 23152885 25192599 12183049 11850402 16169070 16713569 25810899
MYC GAPDH â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199147 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
MAPK3 GTF2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10648599
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
MAPK8 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11259409 11231586
MAPK3 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11259409 16564677 11231586
PRKDC HNRNPU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27303920 25986610 19351595 25030905 19844162
STIP1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 10642522 21235734 21360678 26804907 11413142 24949977 19875381 10786835 20704274 21170051 26496610 27353360 25036637 19996313 9452498 18285346 24462205 22315411 20159553 22729780 22504172 11877417
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
MYC HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19022255 12695333 14519204 21995449 11983916 11085504
HUWE1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26279298 16915296 34761308 16969074
MYC IMPDH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18628958 18677108
MAPK14 KHSRP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16364914 17570479 26708421
NPM1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
MAPK1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MAPK1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 10197981 34504019 18775330 20659902 8226933 9620846 16156666 9604935 18988627 12193595 11027280 8388392 27153775 31995604
MAPK1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19218245 18032789 18729074 16156666 19914161 23331499 19914168 24080014 8226933 14512875 15520018 20736297 26497676 12193595 26297431 18988627 8388392 10197981 15241418 18775330 9604935 9380693
MAPK14 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 10197981 15241418 14512875 16156666 15520018
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK3 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MAPK3 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MAPK3 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 10197981 15241418 24080014 18775330 8226933 16156666 9604935 12193595 8388392
MAPK3 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17081983 16156666 19413330 11027280 9620846 33676893 23331499 8226933 20068231 18988627 12193595 18491316 18691976 8388392 19651622 10197981 18775330 19115199 9604935 15212693
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
PRKDC MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11749722 16319174
MAPK8 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10601313 25714018
MAPK8 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19651622 10551811 17081983 18767875 20068231 91332050 1651323 1748630 16713569 11243879 18669648 15210690
MSH2 MSH6 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11307145 11948476 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 16879101 17129768 17303408 17395641 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261 23507534
MSH2 MSH6 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11307145 11948476 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 16879101 17129768 17303408 17395641 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261 23507534
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
MYC TXN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16099847 12695333
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
SFPQ NONO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17452459 21988832 17145710 17507659 12403470 11259580 30021884 10858305 18042045 20421735 25959826
PRKDC TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19444312 27432546 23370278
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
USP5 UBC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 19285159 20622874 22878415 26235645 18482987 19373254 16007098 31663737 25970461 27848959 17550899 26876099 24681967 23314748 17980597 16564012 27066941 17692280 22428841 8841133 22216260 24424410 34648286
DDB2 DCD â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
ATM LMNA â—¼   KO_DOWN_REGULATES ✅ - -1.21 1.2 PKG 28854368
PRKDC ATM â—¼   KO_DOWN_REGULATES ✅ - -1.5 1.49 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
DDB2 VIM â—¼   KO_DOWN_REGULATES ✅ - -2.33 2.32 PKG 28854368
DDB2 ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -2.39 2.38 PKG 28854368
ATM VIM â—¼   KO_DOWN_REGULATES ✅ - -2.44 2.43 PKG 28854368
ATM ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -4.02 4.01 PKG 28854368
MSH6 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -4.08 4.07 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
MSH2 MSH6 â—¼   KO_DOWN_REGULATES ✅ - -5.11 5.1 PKG 28854368
MSH6 MSH6 â—¼   KO_DOWN_REGULATES ✅ - -5.12 5.11 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368