PKG

Protein list:

SMAD2 PITX2 ACVR1 SIN3B TGFB3 STK11 PTK6 FKBP1A TGFB2 RBX1 INHBE GPC1 RBBP4 KAT7 CALM2 NUCKS1 SAR1A RBBP7 CTBP1 CALM1 NCOR1 HSPA8 SKP1 TFDP1 CDK1 CITED1 CALM3 CUL1 SAP30 RBL2 E2F5 SIN3A SAP18 GGCX FBN1 MAPK11 HGS UCHL5 RANBP3 CTDSP2 BMP2 LEF1 ITCH CTDSPL CTDSP1 MTMR4 CAMK2A KAT2B PPM1A MYC RNF111 STUB1 RHOA SRSF5 MTCH1 TUBA4A EIF5B SMARCC2 DNAJA2 ANP32E IL1RAP DOCK9 STRAP TSPYL2 TCEAL6 TSC2 USP7 SMARCA4 TPT1 SARG E2F4 TUBA1B FAM83G UCHL1 ZFR TOP1 ZNF510 AKAP8L SNIP1 YAP1 PMEPA1 SKI ACVR2B PSPC1 RAN EID2 RPL9P9 MYO5A CCT6A ZNF106 ERCC3 CDK2 RGCC SP1 DHX8 LEMD3 SENP2 S100A4 PARD3 NFYC TRMO MAP2K1 CCDC25 NEFM INSR SRSF11 HYAL2 EIF4A2 CLTA USP2 GTF2IRD1 ESR1 MEF2C ATF3 EPHB6 WWTR1 DDX1 TNRC6B KIF5B TFDP2 CUL4B RIMS1 PML RSF1 EZH2-A PBDC1 PRDM16 CHGB SLC25A6 POU2AF1 SYT1 DRAP1 SQOR LCK RASA1 ZEB1 NOTCH4 ETV4 PIK3CA IFT57 USP15 ATP6V1D TP53 FBP2 BPTF KIAA1109 RELB SPART SORBS1 NCOA3 PIAS3 SUPT6H SH2D2A FOXO3 GLI1 LRPAP1 RUNX1 TCF12 HIPK2 RPS3A NFIA OVOL2 MCF2L PPAN NEDD9 CAV1 SURF6 MED6 SMAD1 FOXO4 SEMA6A CORO2A KAT2A RUNX2 BRCA2 DOK1 NAP1L1 ESF1 GFM2 CDK4 KDM6B TAF3 RBL1 CSNK1D IRF3 CDK9 JUN FHL2 CDC16 S100A1 ATP1B1 CDK8 EIF3D CAMK2G MED24 FHL1 ARID1B HSPD1 DVL1 SMARCC1 TPR HDAC2 CHUK TP63 HNRNPA3 DNAJB5 WWP2 GFAP TRIM28 ATP5ME DPP10 SOD1 FHL3 WWP1 ARID1A TERF1 ERC1 PREX2 CUL4A ELAC2 CAD GFER BEX3 MEF2A HMGN3 FOXH1 SMAD6 PPP1R9B SLC25A5 HCVGP1 DLX4 USP9X MIR30E POLR3D PRMT5 MKS1

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Protein:

Eg: PBRM1 | ARID1A | BRCA1

Function:

Eg: Homologous recombination

Path:

Eg: SMC5 > DMC1 | PBRM1 > BRCA2

Relationship:

Full list of relationships

Graph tools:

Note this may take some time with > 30 proteins

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PKG Score Threshold: 0.8

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Source	Target	Relationship Type	Directed	Sign	DB Score	PKG Score	Database	References
ACVR1	FKBP1A	◼ PHYSICAL_INTERACTION			850.0	0.85	STRING	36370105
ACVR1	SMAD1	◼ POST_TRANSLATIONAL_REGULATION	✅	+	28.0	1.0	Omnipath	19651622 9748228 23331499 9335504 10085121 10652350 9136927 10583507 16189514 11792802 18988627
ACVR2B	ACVR1	◼ POST_TRANSLATIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	23331499 16446785
ACVR2B	BMP2	◼ PHYSICAL_INTERACTION			871.0	0.87	STRING	36370105
ARID1A	ARID1B	◼ PHYSICAL_INTERACTION			870.0	0.87	STRING	36370105
ARID1A	SMARCC1	◼ PHYSICAL_INTERACTION			952.0	0.95	STRING	36370105
ARID1A	SMARCC2	◼ PHYSICAL_INTERACTION			989.0	0.98	STRING	36370105
ARID1A	SMARCA4	◼ PHYSICAL_INTERACTION			992.0	0.99	STRING	36370105
ARID1B	RELB	◼ PHYSICAL_INTERACTION			2.0	0.8	intact	14743216 5216883
ARID1B	SMARCC2	◼ PHYSICAL_INTERACTION			943.0	0.94	STRING	36370105

Showing 1 to 10 of 663 entries