FMR1
|
CCAR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
TP53
|
CCAR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20160719
20074560
|
CSNK2A2
|
CCAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24962073
|
CSNK2A1
|
CCAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24962073
|
HNRNPC
|
CDC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CDC5L
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
AKT1
|
CDKN1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12244303
11231573
|
SOX2
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
|
CDKN1A
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16616141
5218511
|
HNRNPK
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16360036
|
COPS5
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18926707
|
COPS5
|
TYK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24043623
|
TP53
|
CSNK2A2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12393879
11239457
|
HNRNPLL
|
DDX39B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14667819
5216829
|
GRB2
|
DDX39B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
DDX41
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
DDX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
SF3A2
|
DDX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
DHX9
|
DDX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
DDX5
|
HNRNPA0
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
DDX5
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
DDX5
|
HNRNPH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
MYC
|
DDX5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11085504
|
GRB2
|
DHX9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
HNRNPA2B1
|
DHX9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6542847
18519039
|
SF3A2
|
DHX9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
DHX9
|
ZC3H18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
DHX9
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
BMX
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
SH3KBP1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11894095
|
TP53
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
HNRNPK
|
ELAVL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
SF3A2
|
ELAVL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
ELAVL1
|
SIRT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17317627
|
ELAVL1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19884656
|
ELAVL1
|
DUSP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18490444
|
ESR1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16704985
11279135
|
MAPK3
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24530506
|
EP300
|
DDX17
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20663877
|
EP300
|
DUSP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20626350
18504304
|
MYC
|
FBXW7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20638938
19366810
|
FBXW7
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20571051
|
FMR1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17592139
|
HNRNPC
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
FYN
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9694876
7737275
|
LYN
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9209406
8400282
|
LCK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9694876
7737275
|
GRB2
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
MATR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
CBLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
PABPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
HNRNPF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
PPIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
HNRNPH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
MAPK3
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7739560
8816480
|
VAV1
|
GRB2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
GRB2
|
CBLB
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
GRB2
|
ITK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10636929
|
TP53
|
HMGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6547598
9472015
|
ESR1
|
HMGB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17922863
18414489
|
QKI
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TP53
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8200620
21821029
|
RBM7
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
NCK2
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
SORBS3
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
SENP2
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8409140
23092970
|
MATR3
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
PABPC1
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
UBE2I
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
GRAP2
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
HNRNPK
|
HNRNPA0
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
HNRNPK
|
CCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
HNRNPK
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HNRNPK
|
DDX17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
HNRNPK
|
PRMT1
|
â—¼ METHYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
6803829
19101556
|
TYK2
|
HNRNPK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
29892012
25416956
|
HNRNPK
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8349701
|
SRC
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
TP53
|
MAPK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21187340
16050810
|
MAPK3
|
DUSP1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
10617468
8216666
|
DUSP1
|
MAPK3
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
20347885
8288600
|
MAPK3
|
METTL3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
33217317
|
MAPK3
|
PCBP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17475908
|
FUS
|
MATR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
27731383
|
UBE2I
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12393906
20972456
|
SUMO1
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12393906
20972456
|
MDM2
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214648
11588219
|
ARRB2
|
MDM2
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5214648
11588219
|
DDX17
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17226766
|
SUMO1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12393906
11384992
|
RPS6KB1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20657550
|
MYC
|
DUSP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14519204
|
MYC
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15197457
12420224
|
MYC
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11318876
10528192
|
ESR1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
3677090
|
AKT1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17942906
9804616
|
CD2BP2
|
NEDD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16000308
5217817
|
VAV1
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
VAV1
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
PDPK1
|
PRKCD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12840507
9889098
|
ESR1
|
PRKCD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22430216
18414489
|
SYK
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
29352133
22265677
|
QKI
|
RBM14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
RNF113A
|
CCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
ESR1
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21920899
23658738
|
SMAD3
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22610349
23161884
|
SIRT1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21775285
|
SIRT1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
27776347
28583374
|
TP53
|
SUMO1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11420669
21187340
|
SUMO1
|
CTBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12769861
12679040
|
CEBPB
|
TOP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8524227
|
JMJD6
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
24667498
1001819
|
BMX
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217965
16186805
|
TP53
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17184779
5219502
|
AURKA
|
TP53
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
14702041
19121998
|
TP53
|
CSNK2A1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12393879
11239457
|
TP53
|
SMAD3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21900401
|
TP53
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15230856
8732672
|
TP53
|
HNRNPC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18296503
21317560
|
TP53
|
NDN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10713459
10347180
|
RCHY1
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5220017
17568776
|
JMJD6
|
TP53
|
â—¼ HYDROXYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
24667498
1001819
|
TP53
|
DUSP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12890671
|
TP53
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10766163
16713569
|
TCERG1
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
U2AF2
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
U2AF1
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
SF3A2
|
CCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
SF3A2
|
DNAJC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
SF3A2
|
CD2BP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
SF3A2
|
EFTUD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
SF3A2
|
FUS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
SF3A2
|
DDX42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
SF3A2
|
NCBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
SF3A2
|
DDX17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
SF3A2
|
NCBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219711
17332742
|
CPSF7
|
NCK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
ABI2
|
NCK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
NCK2
|
CBLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
NCK2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17310244
11557983
|
NCK2
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17310244
11557983
|
DDX42
|
DHX15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
PIN1
|
HNRNPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
PIN1
|
CSNK2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11940573
5215253
|
NCBP3
|
NCBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
NCBP2
|
NCBP1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
AGGF1
|
CHERP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
PRPF40A
|
CHERP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
U2AF1
|
CHERP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
CHERP
|
RBM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
CHERP
|
CCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
RBM3
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6629313
15518812
|
VAV1
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8986718
16546099
|
LCK
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8946678
9973466
|
LCK
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
CBLB
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8083187
11904433
|
FYN
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17570479
22043010
|
SRC
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16005629
15157149
|
FYN
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7524477
6730342
|
G3BP1
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217568
15743820
|
CSK
|
G3BP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5217568
15743820
|
CSK
|
YTHDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15175272
23331499
|
SRC
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1531699
1311423
|
VAV1
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1531699
1311423
|
SRC
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219079
16966330
|
FYN
|
G3BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217568
15743820
|
FYN
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRKACA
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NEDD8
|
CUL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
intact
|
0806155105
18723677
|
TERF2IP
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
SRC
|
AXL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22327215
8381689
|
SRC
|
CBLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17094785
7033811
|
SRC
|
ADRB2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5219452
17170700
|
SORBS3
|
CBLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CBLB
|
FUS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PDPK1
|
PRKCZ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12840507
9889098
|
G3BP1
|
ITK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217568
15743820
|
ALYREF
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18562279
0802533105
|
PRKACA
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RPS6KB1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214238
11438723
|
PRKCZ
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
18650932
7232391
|
MAPK8
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16306447
|
CBX4
|
BMI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17332741
5219708
|
RYBP
|
BMI1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
24981860
|
ESR1
|
BMI1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24559156
16582100
|
AURKA
|
DDX17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
PRKCZ
|
MAPK10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18667433
17646398
|
CEBPD
|
POU5F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15284209
|
CEBPB
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23251594
22905241
|
CEBPB
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9743233
22139077
|
IKZF1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
UBE2I
|
PRPF40A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
UBE2I
|
HNRNPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
UBE2I
|
IKZF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
PA2G4
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MAP1LC3A
|
PRPF40A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
U2AF1
|
PABPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
ESR1
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16628468
|
CTNNB1
|
EPHB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12408869
12782598
|
CTNNB1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24291232
24482235
|
CTNNB1
|
POU5F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
32803659
21295277
|
HNRNPA2B1
|
HNRNPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ESR1
|
U2AF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12136111
18414489
|
ADRB2
|
ARRB2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
IKZF3
|
GRAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
GRAP2
|
IKZF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
HNRNPAB
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
JMJD6
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
24667498
1001819
|
HNRNPL
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001635
23976881
|
HNRNPA0
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HNRNPA3
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H1-1
|
CHD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
WWOX
|
CPSF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217863
16055720
|
PIAS3
|
PRPF40A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
U2AF2
|
HNRNPA0
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
U2AF2
|
QKI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
U2AF2
|
DDX17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
U2AF2
|
CPSF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219196
17024186
|
WWOX
|
TCERG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217863
16055720
|
SRPK1
|
U2AF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
WWOX
|
CPSF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217863
16055720
|
CPSF7
|
SORBS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
DHX8
|
PRPF40A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
U2AF1
|
PRPF40A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
PRPF40A
|
PCBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
DHX8
|
RBM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
DHX38
|
U2AF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
RYBP
|
FUS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRMT1
|
FUS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
USP11
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7998286
20601937
|
DDX17
|
SORBS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CBX4
|
USP11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7998286
20601937
|
QKI
|
PCBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
H1-1
|
RIPK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
JMJD6
|
U2AF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23455924
8417751
|
H1-1
|
RNF213
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
DDX17
|
DHX15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
802.0
|
0.8
|
STRING
|
36370105
|
NCBP2
|
PRPF40A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
ALYREF
|
NCBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
CUL4B
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
CUL4A
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
DDX17
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
17226766
19995069
33742100
20663877
|
EP300
|
CHD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
26546801
30110629
32699137
15189737
|
AKT1
|
MDM2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.81
|
0.81
|
mint
|
5217292
15527798
|
MDM2
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.81
|
0.81
|
mint
|
5217292
15527798
|
NEDD4
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
19953087
23195959
31390487
|
SUMO1
|
CBX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
20098713
33961781
22467880
24654937
|
HNRNPA0
|
HNRNPF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
812.0
|
0.81
|
STRING
|
36370105
|
CDC5L
|
FRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
CACTIN
|
CWC22
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
EIF3F
|
RTP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
CDC5L
|
DDX23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
GRB2
|
RET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
BTK
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CSK
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23455922
31980649
|
CFTR
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26618866
31324722
|
RIPK4
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29435596
26972000
|
CDC37
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16611982
24189400
|
CDC37
|
PDPK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25036637
31980649
|
MYC
|
CDC5L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
SF3A2
|
CDC5L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20467437
17332742
|
MDM2
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28225217
22032989
|
CUL4B
|
RBM14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
28225217
|
CUL3
|
CUL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
22709582
|
DDX41
|
DHX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
25920683
|
DDX41
|
DDX23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
25920683
|
VCAM1
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
CUL4A
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
32235678
|
EGFR
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
28065597
|
DDX5
|
U2AF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22939629
26641092
|
DDX5
|
DHX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22365833
26344197
|
ESR1
|
DHX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33731348
21182205
19805454
20348541
|
AURKA
|
DHX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23443559
25852190
|
EGFR
|
MATR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20029029
31980649
|
VCAM1
|
EMD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
EMD
|
HDGF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21907836
17620012
|
CTBP1
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21102443
15834423
35016035
16122695
|
G3BP1
|
FMR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29395067
26777405
|
VCAM1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
GRB2
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
21706016
|
MYC
|
MATR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17353931
29467282
|
CUL1
|
MATR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29884807
21145461
|
MYC
|
CPSF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17353931
29467282
|
MYC
|
U2AF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MYC
|
NXF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MYC
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
29467282
|
MYC
|
CUL4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
20551172
|
MYC
|
DHX15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
CTBP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
34147029
|
MYC
|
XRN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MYC
|
SYK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
29467282
|
SOX2
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
PAK1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16452229
12374744
|
VCAM1
|
RBM14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
BMI1
|
RBM14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
SOX2
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17097055
25416956
|
VCAM1
|
TOP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
NXF1
|
XRN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22658674
29395067
|
XRN2
|
DHX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
24778252
|
IKZF1
|
CUL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SF3A2
|
DDX42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12234937
17332742
|
SF3A2
|
CHERP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12234937
17332742
|
SF3A2
|
U2AF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12234937
17332742
|
SF3A2
|
U2AF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12234937
17332742
|
VCAM1
|
DHX15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
DHX15
|
NXF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22658674
22939629
|
DHX15
|
DDX42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22365833
29021621
|
BMI1
|
NCBP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
JMJD6
|
CHERP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NEDD8
|
SYK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24654937
18274552
|
AKT1
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26344197
19262695
|
RIPK4
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29435596
26972000
|
VCAM1
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
NEDD8
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
24654937
|
SPOP
|
BMI1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
15897469
34316702
|
BMI1
|
NCBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
BMI1
|
G3BP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
BMI1
|
CIRBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
BMI1
|
PCGF3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22493164
24981860
|
BMI1
|
FUS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
ESR1
|
CAND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19805454
31527615
|
ESR1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21761334
31527615
|
NXF1
|
DHX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22658674
29395067
|
VCAM1
|
G3BP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
ESR1
|
CTBP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23403292
31527615
|
IKZF3
|
CHD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12015313
30760870
|
VCAM1
|
CHD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
PPIA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
JMJD6
|
U2AF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
U2AF2
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22365833
26641092
|
U2AF2
|
CCAR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22365833
26641092
|
JMJD6
|
CPSF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
VCAM1
|
CPSF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
FUS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
CBX4
|
PCGF5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24981860
27705803
|
VCAM1
|
PCBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
MBNL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
HNRNPH1
|
HNRNPL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
CSNK2A2
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
DCUN1D1
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
CHD4
|
H3F3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
EFTUD2
|
WBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
CDC37
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16611982
25036637
24189400
|
DHX8
|
CDC5L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34079125
29395067
26186194
|
CDC5L
|
FUS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
20467437
29884807
25192599
|
CDC5L
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
90000000
31413325
17043677
|
MATR3
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
29511296
29884807
26496610
|
MATR3
|
DHX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
29511296
29884807
26496610
|
SIRT1
|
EP300
|
â—¼ DEACETYLATION
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
19047049
|
MATR3
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
29511296
29884807
26496610
|
MATR3
|
RBM14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
29511296
29884807
26496610
|
CTBP1
|
RBM14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
31041561
30217970
|
ESR1
|
EIF3F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
30573685
19805454
31527615
|
ARRB2
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19202075
19122674
11877451
23242524
|
ESR1
|
SRPK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21182205
33731348
31527615
|
CTBP1
|
CHD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
31041561
24981860
|
DHX8
|
JMJD6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PCGF3
|
CBX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22325352
24981860
27705803
|
SREK1
|
JMJD6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AKT1
|
CDKN1A
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
31575057
|
DUSP1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
HNRNPF
|
HNRNPH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HuRI
|
32296183
|
SF3A2
|
WBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
FUS
|
PRMT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
ESR1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
NDN
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
CTNNB1
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
ELAVL1
|
PRKCD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
MDM2
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
FGR
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
31980649
|
CACTIN
|
CDC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
CDC5L
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
20467437
19596686
|
RYBP
|
CSNK2A2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
24981860
|
DDX5
|
DHX15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
SRPK1
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
25852190
|
DHX9
|
NXF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
EGFR
|
EMD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24797263
20937808
28065597
|
GRB2
|
PPIA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31980649
12577067
|
ESR1
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31527615
15961505
|
TOP1
|
DDX23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
34079125
15848144
|
DHX15
|
FUS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
WBP4
|
DHX15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16055720
28838205
|
SRC
|
BMX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
10688651
|
CSK
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15144186
31980649
12485116
|
AKT1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
24412244
28205554
|
ESR1
|
PA2G4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31527615
20348541
|
ESR1
|
CIRBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31527615
20348541
|
RBM7
|
NCBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
26382858
26496610
|
WBP4
|
CPSF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
34133714
16055720
|
CUL1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
ARRB2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
DDX5
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
CDC40
|
GPATCH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
FYN
|
PRKCD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
NEDD4
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
CDC40
|
FRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
CDKN1A
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
CAND1
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
DISC1
|
FBXW7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
ITK
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
32707033
33961781
|
FUS
|
DHX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27460707
29884807
|
EGFR
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
24797263
24189400
7534311
23956138
|
FBXW7
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
8399454
23108047
|
SRC
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16189514
16713569
11964172
9016807
12624098
|
SRC
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32707033
9169421
18070987
22581261
|
SUMO1
|
PIAS3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16524884
19217413
15569683
24654937
|
TP53
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
12397362
5215850
|
SMAD3
|
CEBPB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12202226
12524424
|
SRC
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
17284441
6169640
|
CEBPB
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
FUS
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27460707
29884807
26344197
|
RNF2
|
PCGF5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
24981860
|
DHX9
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
FYN
|
PTK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
EFTUD2
|
FRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
EGFR
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
CEBPB
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
CSNK2A1
|
SIRT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
855.0
|
0.85
|
STRING
|
36370105
|
HNRNPA2B1
|
HNRNPAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
LCK
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
31980649
|
CDC5L
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20467437
21145461
|
CDC5L
|
DDX41
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20467437
25920683
|
CDC5L
|
U2AF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20467437
22939629
|
NEDD8
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16503656
18274552
31973889
24654937
16620772
23201271
10597293
21145461
|
CUL4B
|
PPIA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21145461
28225217
|
CUL4B
|
RBM3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21145461
28225217
|
CUL4B
|
DHX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21145461
28225217
|
CUL4B
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21145461
28225217
|
EGFR
|
XRN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24780295
24189400
|
EP300
|
SMAD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9679056
15824515
15688032
16109717
15345715
20564330
9843571
15133024
10497242
17469184
15623506
10575014
15588252
18055455
16876108
21567395
11134049
12743039
11058129
|
ITK
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10636929
8985255
|
MDM2
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20708156
24804778
|
ARRB2
|
NEDD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23208550
18544533
|
SMAD3
|
NEDD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19953087
32296183
15496141
21685363
|
SUMO1
|
CEBPB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20194620
18820298
|
CUL3
|
DHX15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21145461
26949739
|
CUL3
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21145461
26344197
|
SRPK1
|
U2AF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28514442
33961781
9472028
23602568
32707033
|
ELAVL1
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
AKT1
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
PABPC1
|
TOB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
CBX4
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
AKT1
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
CDC5L
|
U2AF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20467437
22939629
26641092
21536736
|
CAND1
|
CUL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
21249194
31253590
12504025
21145461
22405651
|
NXF1
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22658674
23143267
29395067
|
NEDD4
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19953087
33762435
29455656
|
EGFR
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
ITK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
CFTR
|
EMD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26618866
31324722
17110338
|
MYC
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15616592
16287840
32140074
16126174
17157259
12776737
|
AKT1
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21901101
15224190
21775285
20333651
18182168
11116148
|
SRC
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26695438
10973497
|
GRB2
|
LRRK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31980649
24947832
19380743
20697350
|
LYN
|
BTK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11226282
8058772
11598012
8629002
8630736
|
SUMO1
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21316347
12917636
22411991
18583933
15876874
12393906
12297306
20972456
11384992
15876864
17000718
|
MYC
|
TOP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17314511
20195357
30415952
29467282
|
AKT1
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24886428
23397142
14749719
12138087
|
CUL4A
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17079684
21145461
32235678
|
WBP4
|
SF3A2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16055720
30021884
|
SF3A2
|
DHX15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24304693
12234937
17332742
|
CBLB
|
NCK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
16189514
25416956
16713569
33961781
26186194
21516116
26871637
|
CSK
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16713569
8262983
7524477
1985196
|
ITK
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10636929
16713569
8810341
|
CEBPB
|
CEBPD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
1840554
20102225
|
NXF1
|
CPSF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34133714
22658674
29395067
|
IKZF1
|
CHD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
30760870
11003653
12015313
33961781
|
JMJD6
|
U2AF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
23455924
|
ARID1A
|
ARID1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
DDX17
|
DDX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
CHD4
|
IKZF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CSNK2A1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
G3BP1
|
PABPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CBX4
|
CTBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CDKN1A
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
FYN
|
CTNNB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.87
|
0.87
|
Signor
|
12640114
|
GRB2
|
PTK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
EFTUD2
|
RNF113A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
RNF113A
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
COPS5
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
EP300
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
DNAJC8
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CHERP
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CAND1
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CWC22
|
RNF113A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
AURKA
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CSNK2A2
|
RYBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
SUMO1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
DDX42
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
PIN1
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CSNK2A2
|
PCGF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CDC37
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22504172
12176997
31980649
24869908
|
DDX39A
|
DDX39B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
ESR1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16713569
28065597
20935677
11887937
17284441
|
LRRK1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24947832
28065597
29513927
|
RBM14
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11443112
33742100
16713569
|
FUS
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18509338
30110629
33742100
|
LYN
|
FGR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
32707033
31980649
|
CUL4A
|
NEDD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16503656
19617556
22474075
18274552
31973889
24654937
16620772
12481031
19295130
23201271
16964240
10597293
21145461
18247557
|
CHERP
|
DHX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
22365833
|
EPHB3
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9674711
16713569
|
SMAD3
|
PIAS3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
14691252
|
SRC
|
RET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
33961781
32062451
10070972
|
NXF1
|
U2AF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11724776
16189514
16713569
|
IKZF1
|
IKZF3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
9155026
26823144
33961781
10204490
|
SREK1
|
SRPK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32707033
14559993
23602568
|
TP53
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
PRMT1
|
PRMT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
NCK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
ARRB2
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
MAPK8
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CD2BP2
|
DDX23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CSNK2A1
|
CSNK2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
SIRT1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
PCGF5
|
RYBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
HNRNPA2B1
|
HNRNPL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
PCGF3
|
RYBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
CIRBP
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
RCHY1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25036637
31980649
12471035
24189400
23956138
|
CUL4A
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17041588
31973889
23555860
18593899
33961781
16964240
21145461
30945288
32140073
|
SMAD3
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15464984
18548003
19917253
|
CBLB
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24797263
11375397
20308550
19531499
33848699
10635327
30515972
18271526
28572092
10086340
16729043
31959764
16702950
15657067
|
EGFR
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
24658140
12522133
25402006
|
EGFR
|
RET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
28460442
|
EGFR
|
FGR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
GRAP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22973453
24658140
25402006
31980649
|
EGFR
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
RET
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
32062451
9393871
8183561
7665556
10995764
15677445
|
MATR3
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
90000000
31413325
17043677
29961565
|
MATR3
|
FUS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
27460707
27731383
29884807
26496610
|
MDM2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12897156
11178989
16713569
10766163
17545634
31012223
|
MYC
|
CHD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17314511
30415952
29467282
|
MYC
|
CDK4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22094256
28205554
28628118
21988832
|
SENP2
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11997515
14673145
17099700
12192048
15896780
15296745
|
TP53
|
RCHY1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
17568776
5220017
|
TP53
|
RCHY1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.89
|
0.89
|
mint
|
17568776
5220017
|
XRN2
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
90000000
31413325
17043677
29961565
|
NCK2
|
ABI2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
29892012
16189514
25416956
32296183
16713569
33961781
26186194
26871637
|
CSK
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12387813
17525734
9208935
7678701
21746865
7513429
|
SRC
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
31980649
19711372
9169421
33961781
16966330
|
TYK2
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9196040
16189514
16713569
|
SRC
|
ADRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11013230
17170700
|
BMI1
|
RYBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
34316702
20601937
27705803
22325352
33961781
24981860
26186194
24457600
|
SRPK1
|
U2AF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
22365833
33961781
9472028
23602568
|
SRPK1
|
DHX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
23602568
34079125
|
PCGF3
|
RYBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
34316702
27705803
22325352
33961781
24981860
26186194
|
PCGF5
|
RYBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
34316702
27705803
22325352
33961781
24981860
26186194
|
NCK2
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
CD2BP2
|
EFTUD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
COPS5
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
ADRB2
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
BMI1
|
RYBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
CDC5L
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
GRB2
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
DHX15
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
METTL3
|
WTAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
SRPK1
|
U2AF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
CUL4A
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
ESR1
|
CCAR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21596782
20074560
17473282
|
CDC37
|
PRMT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDC37
|
CDK4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23455922
28514442
8703009
21871133
25036637
11867521
9150368
24189400
17353931
24292678
8666233
33961781
24981860
26186194
32707033
27339980
21675959
|
CDC37
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32707033
33961781
31980649
11085988
|
SIRT1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23474493
15130752
21719763
|
COPS5
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18926707
17879958
|
CAND1
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31973889
28225217
26496610
25435324
12504026
12609982
21145461
34026424
|
NEDD8
|
CUL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28522566
24076655
28514442
31253590
18805092
18274552
22405651
21119685
24654937
33961781
20847044
23201271
10597293
21145461
18247557
|
DDX5
|
FUS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
DDX5
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25114211
19995069
19596686
|
DDX5
|
PRMT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14631847
28539435
14675539
|
DDX5
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
25218447
17369852
25114211
|
DDX5
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20663877
19995069
33742100
12527917
|
DDX5
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20663877
19995069
25604459
12738788
20308691
11250900
21182205
10409727
|
EP300
|
DDX5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12527917
20663877
|
DHX9
|
NXF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22658674
20123736
16713569
18596238
10924507
22939629
|
SRC
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
17284441
6169640
|
NCK2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
16713569
22973453
24658140
10026169
1333047
9737977
25402006
9843575
|
EGFR
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24797263
31980649
24658140
25402006
16729043
|
EGFR
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
22973453
24658140
23764002
25402006
16799092
34079125
23866081
|
EP300
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15154850
20234175
16713569
11070080
9809062
28196907
15013777
|
EP300
|
CEBPB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28428115
9343424
14630807
12471036
|
EP300
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19887647
11782371
12738788
25728767
11867769
12479814
23065768
15308690
20388208
14761960
22227247
8799122
20348541
23403292
12714702
11581164
16713569
19838210
18765668
16645043
30418174
12574227
|
MDM2
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9809062
11070080
16713569
|
FBXW7
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27795300
31569395
35140242
15150404
33494392
15498494
28007894
23750012
31638140
17646408
28209614
16023596
17157259
25716680
20970423
23791182
32021252
30606768
32345600
17873522
33821962
31152129
20848231
32047362
22524983
17314511
25720964
31285543
32350066
33086033
15103331
|
TP53
|
FBXW7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23518350
19366810
12824889
|
TP53
|
FBXW7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
31346036
12824889
|
FBXW7
|
AURKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15592418
33824269
|
PTK2B
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
10679059
12626562
9763606
|
FN1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18624398
19738201
|
FYN
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7499280
9344857
|
GRB2
|
IKZF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
32296183
25416956
27107012
|
LYN
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9209406
8677749
7539782
|
MAPK3
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14993270
|
MAPK3
|
POU5F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23024368
|
MAPK3
|
SORBS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15184391
17486060
|
AKT1
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
MDM2
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17984062
15878855
32450252
26545496
12488444
11588219
21988832
21466165
33649538
21389118
18544533
21081496
32828283
12538596
|
TP63
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11714701
9405685
12374749
|
MDM2
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20571051
|
MYC
|
PIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26655473
29467282
15048125
19131971
|
NDN
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
26384308
24349431
|
CEBPB
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21098707
20581311
16585579
|
MYC
|
CEBPD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21143913
20426839
17471507
|
MYC
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16846534
16489011
18562319
|
MYC
|
CUL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10970882
12835716
|
MYC
|
RBM3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
TOP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
SMARCAD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16376880
16915296
|
SH3KBP1
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
7148030
16407834
1209329
|
PRKCD
|
PIN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
12056906
27558335
19372727
|
PRKCD
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17183360
16483929
|
PRKCD
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
25639486
|
SUMO1
|
CTBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
20176810
20098713
12679040
|
SUMO1
|
DDX17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22713328
19995069
25114211
|
ESR1
|
SUMO1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15961505
24119295
18404132
|
TP53
|
PIAS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24584189
11877452
|
TP53
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15212714
20097177
18840615
|
RPS6KB1
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18769144
|
CUL4A
|
CAND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17079684
21249194
22474075
12504025
15448697
18606781
31973889
12609982
27203177
12504026
19295130
16964240
21145461
22405651
|
CUL2
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
CAND1
|
CUL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21249194
21778237
12609982
12504026
18173839
22405651
|
PIN1
|
SMAD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21988832
19920136
21685363
19122240
|
PRKCZ
|
PIN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
12056906
27558335
19372727
|
AURKA
|
PIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23970419
|
CUL3
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
FN1
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16040750
14754902
10446041
|
PTK2B
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
10679059
12626562
9763606
|
PRKACA
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20658524
|
AKT1
|
SMAD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16362038
25241761
|
SMAD3
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16469949
12207925
15525600
|
SMAD3
|
CEBPB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12202226
12524424
|
FN1
|
ITGA4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
20644254
22067905
24202395
|
CAND1
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17079684
17290223
12504025
25435324
12504026
12609982
17439941
21145461
22474075
23019411
28715492
22767593
17438373
12706828
23453757
22013077
18173839
22405651
16036220
29499133
21249194
18826954
21169563
15537541
21778237
27542266
29103612
16861300
12684064
|
CAND1
|
CUL1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
12504025
12504026
15537541
|
SPOP
|
CUL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22911784
21577200
21988832
19256485
28216678
29160310
25011449
30244836
16524876
22013077
22632832
33961781
25278611
19261606
31559706
|
CUL3
|
CAND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21249194
16449638
22013077
12609982
21145461
22405651
26286618
|
ARRB2
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21118812
17620599
12070169
10097102
|
FN1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16040750
14754902
10446041
|
SRC
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24498420
14766010
15604093
11013076
27420286
29720121
12736255
18451880
15140878
23065768
17043237
17627277
7539106
11032808
17363140
20935677
14963108
11564893
12630920
22328528
15020686
15784253
17921256
24051437
10454579
17400812
17284441
16957778
|
ESR1
|
SRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20160136
20460377
22865929
|
PDPK1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
9368760
11825911
14500673
10698680
31467278
12149249
27563096
11313365
11278835
22569334
26264872
10226025
32876514
26256536
21775285
11438723
11445557
23397142
|
POU5F1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23041284
20683952
|
CBX4
|
BMI1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21282530
22078878
9199346
34316702
18453536
20601937
19636380
26496610
27705803
22325352
27647897
33961781
24981860
17332741
24457600
12829790
|
ESR1
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21761347
21761334
18497064
|
CEBPD
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12791769
1714459
11278589
|
CEBPD
|
CFTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7499410
|
CEBPB
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31527615
16651265
7651415
19652226
9817600
|
UBE2I
|
CTBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
20176810
20098713
12679040
|
UBE2I
|
DDX17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22713328
19995069
25114211
|
ESR1
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11457657
10949931
17068199
|
CSNK2A1
|
IKZF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21750978
|
ESR1
|
DDX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20663877
19995069
25604459
12738788
11250900
21182205
20348541
|
ESR1
|
PRMT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
28539435
18657504
11029009
|
ESR1
|
RET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21737465
21947652
22878616
|
ESR1
|
RPS6KB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22286763
21292829
18414489
|
ADRB2
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23208550
24658140
17148612
24561123
27226565
|
IKZF1
|
CTBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
IKZF1
|
CTBP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21900206
16189514
25416956
16713569
10766745
24722188
27107012
|
IKZF1
|
IKZF3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17383641
|
CBX4
|
CTBP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
15592428
20098713
33961781
20361981
12679040
26186194
11583618
9858600
12829790
|
CUL5
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
DDX17
|
FUS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
SF3A2
|
U2AF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
CWC22
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
CSK
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
CBLB
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
PCGF3
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
COPS5
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
CAND1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
COPS5
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
EP300
|
TP53
|
â—¼ POLYUBIQUITINATION
|
✅
|
-
|
0.91
|
0.91
|
Signor
|
12690203
|
CAND1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
PCGF5
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
FYN
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
28514442
25036637
31980649
33961781
32707033
|
AKT1
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
18191226
19122674
19262695
|
BMI1
|
CBX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHOSPHORYLATION
|
|
|
0.92
|
0.92
|
Signor
|
11726515
|
TP53
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
ESR1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
DDX23
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
CACTIN
|
DHX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
FBXW7
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
SYK
|
VAV1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.92
|
0.92
|
Signor
|
11331248
|
CDK4
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
24981860
|
GRB2
|
BTK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
19380743
20936779
|
CTNNB1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
EP300
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
PRPF31
|
WBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
EGFR
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
COPS5
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
CDC5L
|
TCERG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
AKT1
|
PDPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
DHX9
|
PABPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
NCK2
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
CAND1
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
SUMO1
|
TOP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
12149243
12439742
11709553
24654937
15576338
19596686
|
SH3KBP1
|
CBLB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
6170278
12177062
|
U2AF2
|
U2AF1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
8153045
21516116
|
CUL3
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
EFTUD2
|
TCERG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
ALYREF
|
DDX39B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
EP300
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
CWC22
|
FRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
DDX23
|
PRPF31
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
CDC40
|
RNF113A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
UBE2I
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
5219915
17491593
|
HMGB1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
CDC5L
|
RNF113A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CBLB
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CWC22
|
DHX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CWC22
|
DHX38
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
DHX8
|
EFTUD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
DDX17
|
DDX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
22365833
15298701
19995069
22863883
33961781
24581491
10837141
22939629
|
CBLB
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
AKT1
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
32450252
25241761
18332867
12145204
19166854
15527798
20856200
11715018
23397142
11504915
11923280
21930127
|
NEDD8
|
CUL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16503656
23401859
19617556
18826954
18274552
21145461
10318914
24654937
16620772
23201271
31444342
18173839
10597293
10585493
18247557
17132228
|
NCBP2
|
NCBP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
24981860
|
NEDD8
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
6541102
18274552
|
CUL1
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17290223
5219620
|
CUL3
|
NEDD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16503656
19617556
18826954
23936405
18274552
17192413
24654937
17543862
16620772
23201271
33961781
10597293
21145461
18247557
10500095
|
RNF2
|
BMI1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
16710298
5218667
|
RYBP
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
24981860
|
DHX38
|
EFTUD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
CDC40
|
DHX15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
CAND1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
COPS5
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
964.0
|
0.96
|
STRING
|
36370105
|
FYN
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
TCERG1
|
U2AF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
CDC5L
|
DHX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
CDKN1A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
COPS5
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
SRC
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31980649
8845374
21573184
25402006
7506422
10075741
19704002
10971656
23175185
10777553
22227249
20935677
20624308
21268077
17158602
24189400
9020193
16713569
22973453
11983694
24658140
28065597
21278788
17284441
7797556
20333651
7527393
10358079
|
EGFR
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
19254954
7518560
31980649
9416834
7592693
23956138
14679214
10085134
7510700
27059931
21706016
25402006
16799092
16729043
8665853
15657067
24797263
12577067
8810325
7650032
11960376
23799367
25187647
8626525
10026169
19289468
18271526
21278786
7506413
17971399
8940013
20124286
11726515
9886492
10595738
24189400
9020117
19531499
20473329
9020193
8662998
8647858
1322798
8887653
10229072
16273093
25754235
31959764
11370743
16713569
21596750
9685397
24658140
31985874
22973453
11896612
20067773
17242169
19836242
8810340
21278788
30544639
7527043
9050991
11408594
8621459
|
FBXW7
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
28522751
23108047
23322298
28007894
21145461
22388891
29695787
23453757
14603323
22405651
29499133
31285543
25143387
32086376
22524983
11585921
25515538
25720964
26976582
21205095
29103612
33961781
29408378
11565034
32350066
|
NCK2
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
32296183
25416956
31980649
16713569
30886144
10026169
33961781
26186194
11557983
23455922
|
EFTUD2
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
NCBP2
|
NCBP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
23665581
9933612
26382858
31467278
11545740
22365833
26496610
29395067
12374755
26264872
7478990
19668212
22939629
29997244
32814053
29101316
24981860
31448526
17190602
12434151
26344197
|
NEDD8
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16503656
18723677
16620772
23201271
21145461
22474075
18247557
24076655
10772955
17438373
19245792
24654937
21102408
10713156
11027288
21765416
10597293
22405651
12565873
18805092
18826954
18274552
19713960
16177058
22959436
24949976
32726803
19617556
17206147
10318914
17318178
21119685
18264111
18627766
23267066
|
SYK
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
CDC40
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
CDC40
|
CWC22
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
CDC5L
|
U2AF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
CUL2
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
CDC40
|
DHX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
SF3A2
|
TCERG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
DDX23
|
EFTUD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
CUL5
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
GRB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16729043
5218694
|
TP53
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16611888
6599495
|
CDC37
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
SENP2
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CDK4
|
CDKN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
PRPF31
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
CWC22
|
EFTUD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
CDC40
|
DHX38
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
CDC5L
|
DHX15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
DHX15
|
EFTUD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
CDC5L
|
DHX38
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
CDC5L
|
CWC22
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
CBLB
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
21900206
28514442
16189514
25416956
31980649
12577067
31467278
26264872
10022120
9614102
29997244
21706016
32814053
33961781
20936779
10086340
27107012
|
TP53
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.99
|
0.99
|
mint
|
17139261
5219401
|
U2AF2
|
U2AF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
32296183
16189514
25416956
26641092
16713569
22939629
21988832
26264872
22365833
21460037
33961781
8647433
21516116
1388271
11551507
26344197
|
EFTUD2
|
PRPF31
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
CDC40
|
CDC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CUL1
|
FBXW7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
SUMO1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
POU5F1
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
METTL14
|
METTL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CDC5L
|
EFTUD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CDC5L
|
SF3A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CUL1
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NCBP1
|
NCBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CUL3
|
SPOP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CDC40
|
EFTUD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CAND1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EP300
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MDM2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
BCCIP
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19713748
10878006
14726710
|
CCAR2
|
SIRT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18235502
22735644
18235501
33459133
|
CSNK2A1
|
CDC37
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
26755559
18566753
20068231
15082798
18922470
19413330
12930845
27105117
|
CSNK2A2
|
CDC37
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20068231
15082798
19413330
12930845
|
TP53
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
389.0
|
1.0
|
Omnipath
|
9349504
22270849
8749722
21242964
22290440
23874636
23349794
23650552
17280505
16288208
19882681
22948151
8641969
18840648
7777546
9360984
9707425
14614448
15586362
12889596
10597242
18719376
17938176
16343438
9916993
12806965
15024021
10037739
19394332
19749793
22480684
15136035
19501055
22732402
15988033
17307334
18272192
23665236
20331637
10435630
12239594
14743206
24599959
9714336
9652736
19954840
12392301
15339933
9154806
19383287
21295542
16894028
23187802
15248906
14522900
18483411
16261158
11892838
20190809
17167174
18615633
15790310
17916908
19472317
12717415
19789303
16317118
7696178
24584189
22989750
18573881
22532570
9288775
16103882
11890931
17646389
17344317
10753197
8557703
15872011
24356969
11278953
22279545
12902982
9920903
18644983
21524151
16540664
10935506
16537920
19843844
9535786
17878219
9405685
10749849
18656471
11021966
19723072
16778363
18628250
16557594
9614553
21791610
10072388
12203124
12420214
12640112
16601686
20531308
15741235
17317670
18446786
18505818
9224526
17569660
21900401
14517211
12934105
22713239
11313928
15492238
17509529
15985438
14722112
18755897
15489892
23759594
7624148
17786325
9223430
24074410
9525742
11395510
21317932
11444825
18645021
15856024
10559267
18593586
16970927
12665570
10101800
23017582
20696891
9268733
22001409
24821728
23146670
22427654
12573582
19118657
11973611
24096481
20797428
17685229
23066038
10029406
12681065
12433990
18769160
15208672
11152513
8547219
15851483
23474493
24384472
11175333
17158927
23100276
17762884
18951877
12045203
15051477
16107883
18521083
23159636
8603071
20814747
15082782
11375890
21084835
10348346
22244155
21325288
12379483
14580351
17592775
8910340
15566940
12173040
12007564
12609999
8878553
12080472
12384701
22266868
17404570
23329847
7478511
15067082
15007388
16458891
9268365
15728246
17224908
10094833
15897882
18059034
11739748
7624134
17146435
18690848
21528307
21546904
18208621
18172861
17977830
17721438
20817677
22894933
18225552
21642427
11162600
9183012
8647846
10660101
21858218
22514644
18451802
11384995
20673369
7774811
20187950
16230382
17339230
12168779
19630958
8242752
9895308
21606339
11748232
16410722
22611192
16061648
15009091
22503977
8799837
15660129
20473858
20448457
16488074
14612423
21903579
11668476
11313463
17101782
19067706
17121856
10792001
16341121
12925527
7566157
22190353
12782287
9233781
15509808
21245169
17145718
24134839
10498892
18094076
14635196
23208500
20843368
10327058
21969549
9440695
10625687
20885946
12851404
19846554
10910098
14614455
18419600
21552844
24835508
21541551
9472102
11922774
19244234
17903248
9216067
18193090
10566557
18757425
11429705
19608464
8632901
8691637
15184659
12716906
15259070
24559687
7970699
15738655
9588214
16574813
15302882
12560513
16131836
16778203
10522058
11032828
9816111
9108440
15860260
17108107
25024194
9582019
22266186
20036872
9926942
15710329
19243472
17997002
19435914
21093383
23149933
11162506
17678435
11895854
8616838
12748190
17610896
18269916
22086179
21557991
17942917
24821727
11557753
16204065
18645003
24205274
9816061
12226108
24379401
15539944
7753560
15371422
10799578
10777217
16434701
17996705
21957244
9191059
9519881
9207798
24289924
21733196
15496412
20124454
20153576
22172947
10321740
21715977
22253232
8816885
24189165
15882981
8752276
20511722
11514734
20962589
12869419
16733561
19713748
16931520
10499591
16581545
19738071
|
MYC
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
15190211
14519204
15616584
12408868
19174556
21949397
10319992
12553001
16204065
12545156
20878079
21042278
21400515
20190815
16706751
23804320
15757889
10920185
19270520
16452181
12408820
15528212
22371483
12565816
17885207
12384701
11274368
19150257
20551174
15899785
21120446
15071503
15474507
22814619
12835716
12748190
16738884
15711923
18636159
|
TP63
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
15790310
10383130
21480565
12640112
20123734
17404570
16007146
16410722
15965232
12374749
17965458
21093383
23665236
9405685
|
CEBPB
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10982390
15466360
15041706
|
ESR1
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15557281
16628468
20696891
16847062
12151347
11517191
15378598
11274368
16469747
17681750
20301197
22787161
23349794
|
SMAD3
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10878024
9618481
14755691
10601254
16819512
17516505
10506225
14647420
14583455
|
EP300
|
CDKN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10362258
15509808
21858218
22000024
21245169
|
TP53
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
19922265
12897156
19597488
16616141
28433629
20066118
20457558
19749794
6396087
21163364
17371838
21900206
21340684
25241761
12897801
12748190
20182602
11896572
|
MDM2
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17373842
25241761
20086099
14633995
14761977
20308078
|
MYC
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15528212
9618481
12545156
17550342
10454538
15155580
11283613
10920185
11283614
|
ELAVL1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19528229
18519672
|
SMAD3
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9389648
9618481
17550342
12545156
11013220
15155580
11074002
|
AKT1
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11756412
11923280
16697215
20452955
27603133
20398329
18372248
15001356
15808505
10217147
19440234
20138985
12431783
10753973
17855660
19216069
28358423
20214616
11463845
9829964
17570479
17646672
16680151
11231573
15169778
12851486
31575057
25241761
23109003
21933447
10949026
16775416
23886938
26436589
16288292
11715018
16055744
18636226
15023346
9812896
12042314
17680028
24848107
16982699
11779850
10722653
20832730
18570873
20307683
34069970
17052453
15798220
|
MAPK8
|
CDKN1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
12730199
15964852
17325029
19664994
12058028
11779850
17570479
20519948
16964243
18669648
|
CDKN1A
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
23443559
15169570
18850315
9658399
16962592
15232106
9632134
16189514
8622677
15695403
20102411
8242751
9464540
23007395
7626805
9106657
12383116
30193583
17556661
23543736
8756624
|
CUL4A
|
COPS5
|
â—¼ DEMETHYLATION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
19748355
18926707
16401342
18093314
23535663
23583660
22959436
16943200
23535662
|
CUL4B
|
COPS5
|
â—¼ DEMETHYLATION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
19748355
18926707
16401342
18093314
23535663
23583660
22959436
16943200
23535662
|
CSNK2A2
|
ARRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11877451
|
CSNK2A2
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12700239
19141652
12432063
|
CSNK2A2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16083285
1088347
10348343
10884347
16552184
9315650
10747897
|
CSNK2A2
|
CSNK2A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
26186194
27705803
25519132
19011756
26496610
25852190
23455922
|
PRKACA
|
CUL5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19917606
21635549
10898738
12917106
|
DDX5
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
24219989
15660129
20876186
19626115
|
EGFR
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
TP53
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20190820
18359760
9664135
10029407
8152794
11713584
8887630
9285564
19597475
11546792
1586628
18604200
18391986
|
ESR1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12894229
12421825
8200909
21705183
|
SRC
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
232.0
|
1.0
|
Omnipath
|
16414009
17081983
25958313
16943190
15618223
19935697
19305428
25402006
24797263
29285309
7488034
15592458
17389395
16461772
20562096
19275932
17897439
15899872
17570479
2803273
23636329
23246962
25505586
23175185
15615697
23349873
16849545
25356505
11983694
24189400
11756413
25748412
26325669
26150526
14512423
18789131
14750954
31978707
25573954
27495374
20071362
18707149
28759036
16729043
26494466
27716204
25537504
17237269
18687633
25884760
29036202
26936397
17575160
20926745
20935677
15282306
23702846
15476828
9069259
19336574
20421302
15660394
23866081
19377510
9777370
22426783
29321659
33706413
25841779
19840943
18669648
12397069
16843263
18957516
34088769
25077442
14963038
19836242
17653080
19625610
16936701
11960379
15548697
18295415
17523611
21268077
20333651
21399647
23376850
11250711
23942551
19704002
22927910
11160627
31952541
10777553
17016520
2543678
19258037
33883672
17646646
28102297
23873690
26771606
21573184
23119029
19151764
16713569
7797556
25955608
15302935
20407013
28513565
23119185
9990038
21080693
20190765
25347738
14630916
15708852
21822308
20628053
25301722
24658140
19690143
27564112
20802523
29124875
33657368
12101233
21787862
14764607
17284441
12878163
26290602
15951569
16543144
15212693
17971399
14523024
10971656
21278788
8845374
22430206
18083107
29641465
18234969
18460189
17551925
22957061
26571308
17043637
20371672
10358079
16799092
19154417
23066441
28065597
12842895
18180459
17158602
18271526
15657067
25159151
34367939
24919575
10075741
25366117
24349301
17561374
16862179
20215522
31980649
24335899
16037379
18451158
14530278
16505275
12063263
23449029
11311660
|
CBLB
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17145710
19531499
11375397
10086340
12577067
10542134
17635922
10514377
|
LYN
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17145710
31980649
16799092
23866081
24658140
11160627
23764002
25402006
22430206
|
MAPK3
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
1651322
17081983
3138233
15901825
16785992
1939237
91332050
27531070
17570479
2543683
2115882
34086370
17192257
1651323
15302935
|
PRKCD
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
11447289
8321321
11313945
12040186
15302935
6321473
1860884
6090944
19568798
14585353
17496910
21386996
2984676
11940581
85012702
19615955
2987962
12845332
3379075
15567848
16488589
17956904
|
FGR
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
31980649
24658140
11160627
25402006
|
PTK2B
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14963038
11274221
16713569
10777553
|
EGFR
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
19104148
27401557
15371335
16099633
22558232
30747223
12040186
26509276
24816560
12740122
25500543
17318191
19568798
21423209
14585353
34227224
23640056
17496910
17052462
24240237
25164010
14517306
21903109
22200182
16952352
20858269
28035485
9233779
|
EGFR
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
109.0
|
1.0
|
Omnipath
|
9544989
10595738
23956138
27059931
10026169
16273093
11726515
24697349
21596750
19289468
7518560
21706016
23799367
9050991
16317285
16713569
25402006
11370743
24797263
8647858
8887653
9416834
21278786
16799092
8662998
10229072
11896612
7592693
19509291
8810325
24189400
19836242
11960376
7506413
18271526
15657067
10085134
24658140
17242169
7510700
8940013
7650032
8810340
11084343
12577067
7527043
31980649
11408594
19531499
20124286
23178716
9886492
23181695
9020117
8479540
14679214
12648464
1322798
17991782
16729043
17971399
|
EGFR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
20809984
17284441
16713569
11887937
|
EGFR
|
NCK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
1333047
23331499
10026169
9737977
24658140
16713569
25402006
9843575
1333046
|
EGFR
|
LRRK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
24947832
22337768
|
EGFR
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
16273093
10938113
24658140
25402006
|
PRKCD
|
ELAVL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
18285462
20798862
34406862
23921630
19528229
23115237
20086103
28383062
17392515
23978401
24492650
|
ELAVL1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18680106
12963828
18519672
|
ELAVL1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18519672
19574298
|
SRC
|
EMD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
25008017
24609268
19789182
29684168
24365856
17637040
|
AKT1
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
17623675
18182168
16926151
20333651
19158375
17964260
17570479
11116148
25904863
21901101
23275565
16024795
|
PRKCD
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
11020388
17434128
12379484
15006641
18053091
15212693
12590608
|
SIRT1
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15632193
19047049
|
EP300
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15965232
|
EP300
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
137.0
|
1.0
|
Omnipath
|
11907332
25545885
21187340
10706102
16438982
10490106
19339993
15542844
23010591
11433299
19608861
17438265
17906639
16024799
9194564
20234175
23402884
12162806
26229107
16959611
15186775
9744860
11070080
17977830
17189186
22266186
20228809
15664194
19805293
25753752
11804596
26625199
27818144
10648616
16928824
9288740
10942770
12724314
23148227
23728348
15965232
19218448
16678111
16782091
20094059
14612423
24821727
10518217
16713569
9891054
25288747
17452980
14759370
19788416
25156994
18931695
22074660
23880760
15337767
15509808
26302407
22731250
18391200
16543236
19234109
21471221
23307557
25867071
12690203
15558054
18612383
23870121
18243116
19217391
22013068
16537920
16611888
18485870
9194565
12660246
9809062
23796514
11359905
12501250
15295102
19407812
25651062
23329847
16135789
|
EP300
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
9843571
11134049
12743039
15133024
15824515
15623506
16876108
21567395
16109717
17074756
20564330
10497242
15588252
17469184
15345715
11058129
10575014
16862174
|
EP300
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17145710
22290435
19623618
11804596
23343194
22761862
16039586
12776737
17157259
17143292
12660246
15576399
21151179
15522869
17306568
19407812
17666529
21285352
19619488
|
EP300
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11050151
18987336
15806138
15060161
17410209
|
FBXW7
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
15498494
17145710
32047362
28007894
31569395
33821962
20399964
20970423
17157259
16023596
20852628
15103331
15150404
|
SYK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
GRB2
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
GRB2
|
SYK
|
â—¼ SHARES_COMPLEX
|
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
FYN
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
ITK
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11406363
12186560
15661896
25137453
|
LCK
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10652356
11062502
12731048
12740575
15536084
17544292
19290918
20814939
21127503
22513334
23620508
8478617
8986721
9438848
9738502
9751747
|
GRB2
|
SYK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
71.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11907067
11960372
12175651
12393695
12524384
12629515
12640133
13678960
14568985
15099563
15111329
15501236
15520864
15536084
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17101731
17496910
17673906
17883421
19414323
19449109
19909365
20150200015
21149606
21372296
21378271
21910624
22064427
22461508
23390297
23609447
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8189062
8226994
8551221
8837607
9000133
9157999
9295024
9314552
9396765
9570538
9632805
9753319
9763615
|
GRB2
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10077632
10086337
10426994
10567412
10646608
10679059
10714681
10811803
10849438
10898494
10982827
11080163
11447289
11526404
11698448
11754814
11777939
11777960
11907067
11994416
12094222
12165654
12175651
12186560
12616499
12626562
12640133
12740575
12885870
12917349
14764585
15169881
15536084
15567848
15574420
16339513
16582911
16713974
16887996
17070508
17100878
17496910
17673906
18490724
19449109
19909365
20189481
22513334
22786724
22952938
25355530
25539813
26552706
8189062
8226994
8551221
9438848
|
GRB2
|
ITGA4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10086337
10426994
10567412
10811803
10982827
11447289
11777939
11777960
11907067
12175651
12640133
15536084
15567848
15574420
16339513
16582911
16713974
16887996
17070508
17100878
17496910
17673906
18490724
19449109
26552706
8551221
|
GRB2
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
BTK
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20936779
19380743
|
RET
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9393871
16189514
15677445
|
PTK2B
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9560226
10329689
8695788
16713569
19380485
9091579
10749687
10354709
|
CBLB
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
10022120
25416956
21706016
31467278
32814053
9614102
17635922
11375397
8626404
16189514
21900206
20936779
27107012
12577067
10514377
19531499
10086340
29997244
|
SYK
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11964172
16189514
22267732
10747947
|
SRC
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12624098
11964172
9016807
16713569
26103942
20554525
|
VAV1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
8900182
10207103
9013873
15558030
7651724
7809090
8621483
29997244
18692475
7478592
16713569
11406576
9209406
16339550
|
GRB2
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12522133
|
HMGB1
|
BTK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
21873236
11544529
22454496
16439361
15944945
12724322
17726518
|
HMGB1
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12646658
15802534
19931333
22842346
26618107
27048821
27192565
|
TP53
|
HMGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9472015
23063560
11748221
16713569
11106654
|
HMGB1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9472015
23063560
11748221
16713569
11106654
|
PRKCD
|
HNRNPK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17081983
15212693
25104022
16083285
11259409
11231586
16964243
10329716
15302935
|
MAPK10
|
HNRNPK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
53.0
|
1.0
|
Omnipath
|
17081983
20166139
18767875
17322306
20230923
19413330
11231586
19664995
19415658
15302935
16083285
20068231
18452278
18669648
18691976
11259409
17287340
19651622
15212693
17924679
19664994
16964243
10329716
18212344
|
SRC
|
HNRNPK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
7516469
17178840
24642125
12052863
7592945
16854432
16713569
21184736
|
MAPK8
|
HNRNPK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11259409
11231586
|
MAPK3
|
HNRNPK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11259409
16564677
11231586
|
MDM2
|
HNRNPK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19249676
16360036
23092970
|
HNRNPK
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18472002
16360036
23092970
|
HNRNPK
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19249676
16360036
23092970
|
ITGA4
|
LYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12626562
19161977
19454690
19487819
22470492
9003039
9456329
9763606
9973479
|
CSK
|
LYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
19901323
11489946
15626731
10415030
16497976
14967142
16537894
7935444
20068231
18452278
10592173
18669648
9171348
18691976
8612628
8794770
19651622
22711887
1722201
|
LYN
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
9820500
24129562
10022120
18818202
21469132
24607955
18083107
17389395
19285079
11536198
10592173
25045209
7797565
11380624
9857068
7513017
30923129
8621719
10477689
7831290
15701717
27258042
19369195
28082678
8666899
9535867
8657103
14871838
|
LYN
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11131153
|
LYN
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9692543
7575560
15774464
96421649
11812791
20190138
18387943
10319993
15302935
10945993
|
LYN
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
18083107
8629002
12573241
11598012
19369195
10051622
9012831
8630736
9730885
10811866
9052864
8058772
11226282
|
LYN
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18453587
23109003
12495636
17570479
11311138
7529876
10593973
|
MAPK3
|
SMAD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
10197981
16156666
27153775
29577978
|
RET
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
551.0
|
1.0
|
Omnipath
|
15956760
25485910
17240116
20385359
12527803
17621270
23612968
18212246
21860413
18097051
18851832
10645003
25679764
21423210
15007380
19934253
19935718
22356909
9677429
15781651
10849428
17188005
20667468
14625304
34380633
17377139
21423211
20010870
26186445
20736304
12376318
33627405
16740736
21561860
15004239
17901130
15212956
15897464
15143154
18819921
17157789
26297582
12138104
11777927
22158866
23195225
34473994
20494825
14963038
16778204
17391526
27683117
22689060
12444552
31933886
15059947
26823016
15657432
19377875
17142325
15486045
21460222
23431142
11159838
27654866
19941816
14718389
34375550
18593598
17360704
23997214
24501773
16163708
10604992
15297577
17106060
24396487
25893857
20361349
16822962
12554776
18454177
29434871
34530870
16141331
12356731
19169277
20543098
17685427
21478906
18463290
16250012
20534535
21228323
7535768
26617336
15963258
10617652
17196532
19995915
10464310
15315965
12082540
21685939
25730857
18305109
25703330
16928771
15681433
11083859
16076871
20395206
23146907
26246800
21454539
12660819
21220474
15866871
15637081
19858202
34403210
18032526
16195541
21829454
16459330
17209045
12808105
11585739
16162500
25833830
18246127
11864968
24418169
15935618
19925796
20160123
17056593
14998784
18215133
10508618
18775330
18760948
12952943
21768338
17317777
8155326
22258404
15788397
26919095
28213521
21192818
33798093
15851026
26242183
12402043
21868357
17064352
20927383
16380505
15035987
21454675
18957207
19193766
21188622
19050043
16904111
19888469
26073130
20185553
15282551
16790523
23405013
11994288
17510392
32081857
18941537
20930115
19106095
11043579
21499301
20145126
24427291
10958690
15939799
19088846
19286657
18424438
15308678
18198175
27323814
24338688
24252946
19956644
21478903
12014987
23017243
17525129
12511559
17615152
16505244
20122898
12077249
17123942
26035354
11278407
15665049
20531297
17292825
14976148
16449644
16461767
23361053
19261611
11502744
25658205
12149254
30327409
17560175
24352879
26586479
26804906
25779944
34125833
19118012
11352917
16740725
11884401
16464862
16641227
27323830
18063582
22955283
24561529
10779765
10542198
16135812
23564461
17210721
24469048
24803537
21602434
17110601
21045017
11073973
10597231
23687376
34556812
17341659
18692468
17579083
12384403
21408150
25417160
11752053
23325789
17371847
11970985
22327338
26265441
16840783
17283152
26616862
23188829
17239630
21487005
11024037
17053147
24363437
25682201
20234004
12391272
23644655
25638159
20808799
17922836
20129247
24913355
18451171
25483104
26296889
21081844
17404396
11287604
18263590
26317416
15541367
16467309
12765939
16331263
16498402
20485667
11230338
16387841
19543320
7687743
20228268
15630487
16774943
16710359
10803464
16844778
16574647
15994317
17495961
21215800
17590453
26382850
19002495
12909616
20599567
12558965
10667594
24711455
17255109
16038803
12370087
21072043
20008839
18805968
10206983
11875080
20231899
21499296
21908610
16002410
12821943
24292678
17525735
17928416
21057531
25236495
17283137
21659545
24403530
16919488
23378338
22973961
18847491
16682955
20840866
16153436
23542175
24492000
12526087
26556867
12133965
12433918
20065107
14610044
11959800
15580310
21730285
11046056
9124279
14707024
26725216
16452220
22212957
25811962
15696170
11416124
20498373
17157787
21653826
16149052
20022946
34262144
16434970
10558990
18045996
10925301
16280323
25581518
15899879
21441955
20566643
15466476
15657177
11706017
15059847
8444886
18519681
23528009
33513601
20138986
12368275
24608435
17062641
20082306
20375017
17537990
24567333
33820494
10712263
21278199
19011679
20145145
27582276
25640183
21730054
16177091
17250586
15879307
16728403
18299328
24269888
17303383
9482941
17671177
17173941
24095720
15304500
12874275
33828192
11827968
33731431
10799542
15328343
18838481
19036157
17634226
17110082
17855349
31722981
26079947
25002506
14559232
23584478
18593910
17114467
16373398
16931794
17016429
14676826
28415597
12029087
24269383
8626767
20478260
12097262
14764579
12181310
15100319
12384432
15271996
17562849
19036927
19326083
20072652
25940440
11922392
17913704
19494114
25596730
18938240
27449290
12897059
21478911
21123455
26804170
10940302
16624816
26876209
12048182
17150968
21478863
17307705
18658095
24995980
16582879
17289590
33667549
17209041
17890097
21726627
27662093
16843264
19426503
11103941
11940578
17906618
26234813
19029090
15007386
15958730
12576312
17667937
17785202
34480897
20647329
18941890
16446383
25562429
10867021
26985018
16413470
23178720
25578563
34437586
21738699
21258408
20388777
24681954
20459645
12242309
15289328
21575862
16185843
19147767
34497368
19153083
12124352
17371994
17567959
15611080
17297454
23012246
14557270
28542650
15713673
21129803
19460345
10958798
21772273
21900206
19205871
17591920
19217381
12963813
19718025
24469056
16624867
21149447
15728578
33902596
11971971
16455819
19112174
10751321
1835084
11016927
18267069
20410276
21980390
17409387
23831578
21477078
15558056
|
MAPK13
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
PRKCZ
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11035106
12942541
23109003
12900386
15721486
|
DUSP1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
23331499
12676937
7761091
10617468
25241761
8221888
7535768
20347885
7939666
20858750
11278799
9430728
9922370
14695202
|
MAPK3
|
CEBPB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
16009338
12213825
8384717
10995751
12048245
15878863
19327116
19443782
15212693
15367685
|
MAPK3
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
18463697
9155018
21071413
32482868
18988627
15210690
|
MAPK3
|
POLR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12721286
14517250
14662762
|
MAPK3
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
15547943
20080742
14967450
12040186
15173823
12697810
11940578
16227978
12738796
16039586
9722592
17255949
15774499
15187187
19541618
19091303
19565474
17052211
11279232
9271440
18039929
18775330
10601235
12792650
11431469
|
MAPK3
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10781582
11239457
10958792
28937686
9467949
10348343
24194938
9739174
16713569
12955074
10747897
17237827
25767119
18523266
12393879
|
MAPK3
|
TOB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
12151396
19270514
22252318
12050114
|
MAPK3
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
8506364
8618896
8226850
7597029
|
MAPK3
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10949034
18372406
15461668
9528769
12118371
14680484
17615152
15059947
16076840
7491495
12093745
15212693
15528270
7838153
|
MAPK3
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
10197981
15241418
24080014
18775330
8226933
16156666
9604935
12193595
8388392
|
AKT1
|
MDM2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11154281
11715018
11923280
15169778
17680028
20214616
20398329
|
TP53
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
201.0
|
1.0
|
Omnipath
|
23150757
20948295
10871862
10914734
21422812
21957016
14532965
22290440
20663877
20547751
11591713
24339722
11840331
22223137
16492744
15843377
22948151
7888679
20156675
21217645
22180176
8319905
9707425
15831521
17690113
9649502
10688649
9194564
15917661
15090541
20837136
8187772
10788589
17907153
15192123
8440237
11964305
16510138
10856296
15580300
7624148
12208736
21211512
16624812
17848574
11245471
21637567
20588255
10562557
9525742
9270029
16479015
19941079
14602726
15024021
18814047
20036872
10718212
18852133
12374749
18397889
25016801
12755686
22081073
22245141
23365201
8957072
22197810
15856024
20703075
23483203
9645455
19648117
20331637
22301280
14743206
23982177
9486848
15734740
19638633
19671680
17310983
10469568
20659896
10072445
21097889
17237821
11748232
11085543
21750655
16337599
21295542
1614537
9815889
9070662
16585169
9472631
17936559
17139261
11328884
12887889
20858413
9858609
14610316
20080970
19505873
11313463
15684615
18359851
18783169
16202543
9267820
12235242
14990790
15851483
7587074
18336191
21478269
17043642
15361831
18025460
23612020
10208414
11756653
24389645
9071998
9430645
9400998
9371494
23149414
22532570
9271120
10777217
22383580
18781178
12606552
14514686
17318220
11127813
16571800
19085961
9207798
10891494
10065155
11593391
14570892
12902982
19649205
20124454
17390010
19955655
12138177
19663772
23581014
15908423
10321740
23150759
19837670
10348346
18632610
9294611
11956627
12750288
12851404
8313378
9135153
15735665
7958853
8247544
9535786
16501602
18566224
8910340
11046142
9405685
7936649
12173040
17329361
21451571
14704432
23874713
18333294
19541936
22787160
18585004
22085928
12080472
7651818
11179471
10949923
19428175
15592502
8413278
11714701
10566557
18583933
9681831
15550242
15007388
19590512
|
MYC
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15655352
12695333
19649205
10348347
|
ESR1
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12897156
17166846
12750288
8324731
22787161
21169420
19578757
|
UBE2I
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15169778
15340381
15147722
12820959
10722742
19459846
18006823
10721693
19440234
|
AKT1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
11756412
11923280
20856200
20452955
20398329
18332867
19664995
10217147
11154281
19216069
20214616
11463845
19166854
15527798
9829964
17570479
16680151
17646672
12145204
15169778
15140942
25241761
11715018
25209720
17680028
21930127
11504915
29311840
15574337
23397142
|
MDM2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
559.0
|
1.0
|
Omnipath
|
20657550
30005830
17616658
9529249
10321734
33650658
9724739
24462112
24621507
15933712
23826318
24667498
22948151
22653443
23776060
25313037
25241761
19303885
16857591
23246961
19033382
20591651
21149449
25417702
15122315
16579792
27543608
29670376
12208736
17848574
26673821
25277184
23443559
23318437
21060154
15210108
19805293
8875929
8058315
21471462
17879958
25362358
23169665
22301280
21584881
20124408
10980696
26876197
17310983
17380154
15058298
24567357
18665269
30109812
25637791
18467333
22337874
22227409
22389628
15242646
22510990
15950904
15001357
19483087
26540344
14559824
21986495
26556313
20708156
19901969
33765973
32528731
11562347
10202144
22374672
10722742
22083959
21965653
17098746
19234109
30679555
16107876
12690203
22525275
19071110
28542145
12620407
20837658
27129163
9131587
24240685
27031960
10681559
19305137
11744695
19188367
16023600
24659749
17347673
12944468
20395212
22084066
20639885
21454483
12897156
16432196
10347217
10706102
11178989
20174603
16751805
15542844
12842086
11431470
11384992
25739118
15064742
23402884
27462439
16905769
22124327
27215386
12867035
22588298
27336364
14702041
16152627
23776465
22262183
21132010
19411846
18309296
23483203
11709713
18981217
14612427
22920093
23671280
24980433
27905468
25168242
21750659
26238070
22737255
23609977
27282385
20847049
20705607
21075307
28082682
17297477
11697899
17936559
24361594
19098711
15469934
34591612
24998844
16212962
11094089
12915590
17116689
11713288
15144954
23201157
10608892
17591690
25156994
17301054
22444248
26883110
26001071
19160491
22157679
24413661
19357310
23802716
15280377
21317885
11597128
19579266
25624478
18061646
21088494
9223638
10435614
31177307
11331603
22391559
20570896
19941302
9278461
18485870
15604276
18566590
12612087
11046142
14704432
26186194
10935507
16173922
14596917
17159902
25543083
19656744
15848166
18316739
22266868
17056014
19255450
21561866
19590512
11839577
22991965
22266850
24200963
11285227
11713287
22975381
19081178
20660730
26475964
16678796
23261415
20173098
17666403
25464845
32427887
23252402
17438265
20959462
22659184
17470788
22912717
17080083
15247280
19332559
17989425
16870621
18813780
20235143
11278372
10562557
25609649
10561590
19411066
17908790
19568783
7926727
21925390
21988832
24127580
18604177
14499615
17371838
17525743
33061576
21887275
26578655
21084564
16861890
20694676
12552135
22914926
17363365
24643130
1614537
22916255
12381304
34992144
12167711
19857530
15053879
10889512
11486026
22103682
16713569
17110336
17426254
10640350
21316347
21478269
15154850
12529318
16595680
16414131
19597489
23880345
27893708
7686617
27811966
17318220
29997244
27308622
19166840
35044719
16159876
24314634
15313915
25283148
22032989
24926618
18172499
19837670
16215989
23134341
26908445
9824166
18451149
21170087
23572512
21465263
22807444
15013777
16845383
10488081
23946421
11714701
25384516
22474335
25312347
23370271
23150757
18541670
22318540
11925449
21572037
24488098
32066565
17268548
20542919
11572869
16338390
21857681
23150668
19223463
20234175
20484049
11070080
20591429
22575647
11351297
16624812
22411991
20588255
17369817
11223036
15908921
9582019
25103245
17302414
21071676
9450543
31968249
34562520
18332869
14671306
21084285
27856536
30464405
26882543
21726810
33020477
21261729
21268072
12426395
16964247
20659896
19106616
22331460
23728348
10827196
22524527
21098709
9363941
17139261
20080206
14517261
22487680
31652301
17290220
27106262
16866370
24207125
28223335
9271120
15550400
7689721
26350565
10196247
27807478
10766163
15558054
35371302
26203195
29487367
25512388
25954860
18223694
15824742
24842904
14741215
16055726
22085928
32894144
18234963
17875722
18815136
15295102
15308643
15358376
22819825
15094782
|
NCBP2
|
METTL3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9409616
24316715
24407421
24981863
|
NCBP1
|
METTL3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9409616
24316715
24407421
24981863
|
MYC
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
MYC
|
PIN1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
MYC
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
32.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
25002027
28536364
7575488
9618481
|
CTNNB1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21533051
19778454
16510874
12095419
17360646
18852287
15576399
19561604
20300972
19662654
15579438
17724465
9727977
24447505
18679417
12907606
|
SMAD3
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
15930298
20516082
14993291
17132729
16205635
25238097
11689553
17114344
|
ESR1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22396492
21835891
15073177
18193094
11517191
21505052
22892083
8707895
19569049
14722073
18414489
|
MYC
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10962037
10656696
8494784
10348347
19882681
16557594
19086036
15780936
14519204
16112647
11781835
7969121
11789587
9839551
|
MYC
|
IGF2BP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21779431
18414489
21252116
|
MYC
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
14519204
11896591
8376401
10421838
|
MYC
|
HNRNPA2B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12747840
20010808
12695333
|
MYC
|
CDK4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15208653
12835716
24951594
21384303
14519204
22395148
10688915
17728244
11983916
18414489
|
MYC
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20890087
20519624
14744757
20682043
|
PIN1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26655473
15048125
30723410
23716601
|
CTNNB1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19751508
7542250
11967263
22290435
19623618
16574648
23343194
11955436
22270359
22761862
16039586
15810077
17143292
12051714
8666229
22943793
15576399
21151179
16940750
17306568
17666529
21285352
19619488
|
MAPK8
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
19651622
10551811
17081983
18767875
20068231
91332050
1651323
1748630
16713569
11243879
18669648
15210690
|
MYC
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21988832
11602341
17093053
22094256
|
MYC
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
11804592
|
GRAP2
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19124833
9989831
15548136
19574218
|
PDPK1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
11134074
21726627
21209852
10995762
23885116
26009991
26238471
10551809
25335797
|
NCK2
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
26186194
10026169
25416956
10592173
31515488
11557983
32296183
16713569
|
AKT1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11435472
14749719
24886428
14585966
23397142
9032240
12138087
|
PAK1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
18521086
26944939
16778166
18755239
21893191
15178330
19205871
29548483
26554417
27003261
24505617
16452229
15193262
19557173
15642175
12374744
19465939
17604944
25447917
20179234
|
PAK1
|
NCK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
26186194
10026169
25416956
10592173
31515488
11557983
32296183
16713569
|
PAK1
|
PA2G4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19557173
23361053
18283314
|
PAK1
|
CTBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
28007610
12872159
16999872
18354494
20361981
23291169
|
PAK1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
28007610
28423670
23543898
25639486
26547035
22369945
23162742
25472536
21822311
25225063
27713506
27910850
|
PAK1
|
AURKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
24867643
16246726
22864622
21589936
|
LCK
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17389395
18691976
15541367
10319993
19144319
16497976
15133032
17016520
11381116
15302935
|
PDPK1
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
16505477
21310943
11839738
31511386
9748166
25472878
25755284
15811957
15133032
11781095
19664995
15024053
15302935
15949469
14581488
28784722
17570831
18669648
11381116
20058876
17965192
19632318
20501830
|
FYN
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17145710
25241761
11927579
10383400
8621384
28259175
12721299
18387943
10319993
|
SRC
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
15851033
14970215
17569658
19366211
26876198
27203386
15961393
24211614
16982614
17570831
23329791
23329794
15541367
18550549
22689788
28637715
14715667
29422059
17658731
10319993
19138410
11927579
29452094
19632318
15337529
|
PRKCD
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17906639
16314418
16377624
|
PRKCD
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11809767
11146000
1848190
8083204
|
PRKCD
|
PA2G4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17951246
16642037
25691158
21145366
17316401
|
MAPK8
|
SIRT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
29578371
17081983
19007248
23434668
21540183
22622703
17924679
18187866
24296261
18838864
19413330
20027304
21471201
19107194
16964243
18669648
15302935
|
SIRT1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
18235502
11672523
18235501
15205477
35931247
15989956
17964266
25280219
19047049
16713569
19960022
21245319
12006491
19590512
|
TOP1
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
12149243
11709553
25114211
10759568
|
SUMO1
|
SENP2
|
â—¼ CLEAVAGE
|
✅
|
|
7.0
|
1.0
|
Reactome
|
16253240
15487983
16738331
12192048
11896061
17591783
14563852
|
UBE2I
|
SUMO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
21212807
25416956
16713569
18691969
17938407
11735126
25502805
15931224
26496610
16732283
24352468
17353931
18359863
10666456
21174150
8921390
9353268
12924945
21949651
32296183
16524884
17956732
18264111
12764129
10961991
14673145
19684601
17698038
16494873
31515488
23871147
17491593
|
ESR1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20080630
16115928
22787161
12750288
20696891
17681750
17699779
|
CEBPB
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19135161
23564453
19075931
24333671
|
TP53
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11564862
20697347
20729811
21691299
19411072
24473123
20064927
18245266
18758483
18372914
|
TP53
|
DUSP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8702807
20196119
15611668
18403641
23149933
12890671
|
TP53
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12485897
18661553
19763735
|
TP53
|
TP63
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
10606233
16931914
18388131
16516862
14576823
11382762
20442293
23019126
19858204
11238924
11423969
|
TP53
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22607268
23376463
18374905
15958553
10854211
22353755
|
NDN
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24722188
10347180
16713569
23785149
|
CSNK2A1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
53.0
|
1.0
|
Omnipath
|
23443559
15358769
9315650
19413330
11285227
11551930
11883897
22975381
11709713
16083285
1088347
33745968
16552184
10884347
10747897
10673501
7936649
12628923
25241761
21127074
16964247
24725084
10606744
10348343
10951572
|
RCHY1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
21988832
19483087
17568776
24367557
25116336
21084285
12654245
21791603
20452352
19043414
16713569
31630802
27519799
19918835
|
AURKA
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
50.0
|
1.0
|
Omnipath
|
24173284
22864622
25217103
24089029
16713569
19413330
25848977
17999753
23565200
25333414
23201157
16552184
10884347
1956339
26186194
29455673
15469940
15749021
18974145
21502403
17287340
28043820
22396649
92065884
12198151
27933271
22852086
12064478
30266789
25398437
17259342
22350019
25634113
14702041
|
PIN1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
12397362
12388558
17906639
12397361
21741598
16713569
24982848
21900206
|
MAPK13
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15187187
19436832
15140942
10581258
20506250
21614932
16393692
24818748
11274345
|
MAPK8
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
11108663
12531896
16713569
11283254
10706102
19651615
27147566
9724739
15538975
9732264
10581258
10436023
17570479
9393873
11896587
12514174
15580310
18813780
11078726
|
MAPK10
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9393873
16713569
14699954
|
TP53
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11238924
18431400
16713569
|
CAND1
|
CUL4A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
17145710
18606781
19295130
22405651
27203177
17079684
21249194
19231300
12504026
21145461
12504025
22474075
12609982
16964240
15448697
|
NEDD8
|
CUL4A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
9694792
18805092
21145461
19250909
19231300
|
NEDD8
|
CUL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16620772
15688063
11696557
21145461
|
CDK11A
|
EIF3F
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12446680
19245811
|
PRKACA
|
PIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11723108
10037602
22926167
21714498
23090969
|
PIN1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16713569
11533658
|
NEDD8
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
19617556
18826954
25349211
25314029
18206966
21940857
23201271
26906416
19250909
25531226
27030794
|
NCBP1
|
WTAP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9409616
24316715
24407421
24981863
|
NCBP1
|
METTL14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9409616
24316715
24407421
24981863
|
SRC
|
BMX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
27601470
17570479
16189514
10688651
|
ITK
|
BMX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12573241
|
BTK
|
BMX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12573241
|
SYK
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
SYK
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
10358164
11907067
12524384
14568985
15536084
17101731
19909365
20150200015
21149606
21378271
21910624
23609447
8189062
8226994
9000133
9295024
9314552
9396765
9632805
9763615
|
VAV1
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
8900182
7518558
23331499
12573241
8629002
23180781
11331248
11262396
10592173
16189514
10092764
8630736
8986718
29145629
9151714
16546099
8809042
24243840
|
FYN
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
7797565
7513017
17570479
10477689
9535867
16713569
|
SRC
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
7513017
17353363
17570479
16189514
9389695
23100514
|
CBLB
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
12771181
16189514
27428901
10022120
|
SYK
|
FGR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11672534
15536084
|
SYK
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
9560226
8816475
9988732
15105428
9727056
10747947
14624447
|
SYK
|
IKZF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23071339
|
SYK
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
8798764
19664994
15536084
8621719
8798676
16497976
25990959
7518561
8845015
16189514
7539035
15659558
|
SYK
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
18083107
8629002
28368423
11598012
28359287
29455639
19369195
10051622
9012831
8630736
28088788
11226282
|
LCK
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
LCK
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
10398592
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
LCK
|
ITK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
CSK
|
LCK
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
7.0
|
1.0
|
ACSN
|
10790433
11181701
12485116
15713798
19290918
8011291
8986721
|
PTK2B
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9257837
9091579
|
CSK
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
56.0
|
1.0
|
Omnipath
|
20346773
19901323
10692391
11489946
22566970
24463463
2141684
16497976
15592455
20813252
10799545
14967142
27547268
24764511
28522807
16537894
12485116
8193535
24227778
17897955
8183556
22426112
89123626
15489916
14610046
23109003
18691976
28448599
17947241
1639064
12414720
15144186
27460989
24816556
22507872
8631775
15743820
25979654
8945479
11181701
27045023
25595912
15259016
|
LCK
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9500442
10571988
25386784
11145737
7539106
27748765
|
LCK
|
ITK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
21747996
28516764
19132916
23109003
20305788
23982207
15771581
19690332
28644030
15144186
9312162
12842872
17192257
23946894
|
LCK
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
20028078
24332539
898671
16285729
15708849
17050525
15699036
17570479
11005864
10669745
10636924
|
CSK
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10790433
11181701
12485116
15713798
19290918
8011291
8986721
|
PRKACA
|
CSK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
9224730
11181701
20826718
31125786
12600271
|
CSK
|
FGR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
11489946
7515063
16537894
8612628
14967142
|
CSK
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
55.0
|
1.0
|
Omnipath
|
11489946
23051580
20657842
20337577
7592628
23824743
21940449
26453921
22323292
14665621
17525734
14967142
3103926
23159740
16227616
1383688
12387813
20525307
10698938
7525268
19534553
16537894
26234813
10592173
12468645
7513429
24632723
7687537
21442427
22689825
25372749
11007774
9208935
18614016
28974561
21632985
19369195
17855352
7678701
23378895
9523754
|
CSK
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
1985196
8262983
11489946
16537894
9647655
25720756
18691976
10366594
19369195
1533589
1699196
7524477
16713569
15713745
14967142
|
GRAP2
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11007481
8986718
10395673
9099726
|
FYN
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10591186
10648627
12218089
12731048
15699036
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
9822663
|
SRC
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17686471
8986718
11007481
10395673
9099726
|
CBLB
|
VAV1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
7.0
|
1.0
|
ACSN
|
10426994
10646608
11526404
11907067
15536084
16713974
19592273
|
FYN
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11262396
15699036
11005864
9438848
16713569
15933714
9822663
|
FN1
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGA4
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12626562
19161977
19454690
19487819
22470492
9003039
9456329
9763606
9973479
|
FYN
|
SH3KBP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
17350651
23052211
23506116
16529723
|
CBLB
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15208330
16503409
32296183
25814554
8083187
|
FYN
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
20026641
22264731
24511551
25241761
22340496
12640114
25803041
26509276
|
CDK4
|
SMAD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
10197981
12193595
15241418
16156666
|
CUL1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11359933
|
AKT1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
25241761
15104092
16362038
21071413
18988627
26297431
15048128
|
CDK4
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
34003249
10197981
15241418
25241761
19920136
15520018
20068231
17099224
16156666
16189514
19413330
14512875
12193595
33051597
19114991
|
MAPK8
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10601313
25714018
|
PIAS3
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
16189514
14691252
|
SMAD3
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11555647
23331499
|
ITGA4
|
PTK2B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12626562
19161977
19454690
19487819
22470492
9003039
9456329
9763606
9973479
|
PRKACA
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
21224395
20166139
18578522
23979717
31562188
18583710
18707149
17603879
19401330
12837751
11533025
|
VCAM1
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22623428
19738201
11751331
|
FN1
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9117345
9842903
19738201
11010812
|
CUL1
|
NEDD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
CUL1
|
NEDD8
|
â—¼ SHARES_COMPLEX
|
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
AKT1
|
CUL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
CUL1
|
NEDD8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
61.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
15001769
15071497
15340381
15459660
15688063
15703371
16039586
16697054
16713974
16940750
17143292
17652783
17884153
17928543
17936032
18196958
18805092
18931676
19250909
19258535
19270156
19352404
19366350
19411070
19576224
19597341
19619488
19622404
19686080
19751508
19809470
19836308
19847258
19849719
20006983
20558317
20705860
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26885856
7542250
7641885
8666229
9694792
|
CUL1
|
WEE1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
AKT1
|
CUL1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
CAND1
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
45.0
|
1.0
|
Omnipath
|
17145710
12684064
25435324
36076154
23019411
18826954
17290223
17438373
21169563
27542266
16036220
21145461
21778237
22474075
22767593
16861300
18173839
12504026
12504025
12706828
22405651
21249194
23453757
22013077
17439941
12609982
15537541
|
CUL1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10228155
10713156
10023660
|
SPOP
|
CUL3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
21988832
23331499
19256485
28216678
21577200
25011449
34599168
22911784
15897469
22013077
16524876
19261606
25278611
|
SRC
|
AP2B1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
18938240
15592455
17456551
18083107
|
PRKCZ
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
10527887
11447289
19615955
16488589
6321473
8321321
12845332
11313945
16189514
12040186
19568798
15567848
14585353
|
PRKACA
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
19651622
17081983
20166139
2474754
18088087
15546918
19664994
11804588
|
PRKCH
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
11447289
19615955
8621384
16488589
6321473
8321321
12845332
11313945
12040186
19568798
15567848
14585353
|
SRC
|
PDPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
20643654
14585963
16314505
11481331
15212693
12738763
1148133
15302935
|
SRC
|
WWOX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
32185845
26120275
31752354
25441426
19366691
16115915
16288044
18371080
27551439
27845895
25650666
31315632
12514174
15070730
15664696
|
SRC
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
9560226
20028775
19919693
15585656
12495636
16713569
31979355
18083107
15105428
15778498
10593973
17389395
25349423
19534553
11149930
12486027
10329689
22581436
19380485
15166227
12526812
12522270
23109003
14963038
8849729
20001213
9556630
18935208
12345678
12231407
17192257
7529876
15695828
15070849
20381867
14739300
19369195
11274221
26866924
10777553
10521452
20521079
|
SRC
|
RET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11713247
17570479
16189514
10070972
|
SRC
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
22605996
16492141
27177845
23824743
25423132
25850673
24816560
27203386
11836526
22515442
26918136
10593980
15782139
9592087
22056988
12571228
17087658
20840866
23640056
21195420
25164010
26453937
9278444
16831887
23476652
12123611
11279024
14517306
21903109
22200182
20026641
22264731
25041845
12408824
22247700
|
SRC
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
15784253
25364741
17400812
16957778
17627277
15140878
11032808
23065768
12736255
7539106
17921256
27472465
14963108
24487689
25275301
12630920
22865929
14766010
30148069
11013076
15020686
9500442
17284441
|
SRC
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11445557
25241761
23242524
18283331
12600984
|
SRC
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
19109164
23170196
8629002
29455639
10051622
8630736
26165234
9052864
|
PDPK1
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11687500
11747822
12670391
15802604
17680028
18802401
19109239
19122654
|
RET
|
PDPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16314505
11481331
15212693
12738763
15302935
|
PDPK1
|
PRKCZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
12887331
14500673
11222751
18691976
10075713
20332120
9768361
9748166
17335005
10357815
16189514
11141077
16051884
11781095
10764742
14604996
|
PDPK1
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
70.0
|
1.0
|
Omnipath
|
17081983
12429015
15208671
18326039
16286006
11438723
21561857
18802401
19864428
16099428
7545671
7489717
27149630
15388791
12183455
10601311
9465032
26582459
29257917
12967624
24604594
15718470
9427642
10209156
23769967
12586835
15809305
9218810
11500365
14560963
9271440
20932932
12370290
11914378
11684675
17680028
14993219
19570988
9445476
|
PDPK1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
156.0
|
1.0
|
Omnipath
|
15505410
12538620
12176337
19951971
24352480
11752451
19401591
11369519
10698680
10601311
15718470
24950409
20481595
24169049
10570282
16798838
14993273
11500365
9368760
19844585
17680028
7637810
9169478
26256536
7722458
9094314
12750173
11438723
18802401
9252186
23331499
18456494
9104825
10592173
16189514
20361045
18988627
11278835
20163786
20333297
20041157
12808134
19602588
8630736
10207050
11241670
10438924
9868760
25912234
20153221
25582703
11445557
21775285
12149249
14666721
18596232
9512493
23397142
11809791
12167717
21798082
16033886
10679787
16787925
29562639
15550174
21071413
8978681
10833263
19203586
10226025
26937223
14500673
20161206
11136732
11825911
11042193
9642236
22569334
18662999
9736715
12242303
11313365
11598012
11134526
|
PDPK1
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
16026785
20732331
15481030
22493239
10698939
9707564
8706898
20137943
21774789
17192257
22154087
20481595
12372837
16765046
|
ITK
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
12445832
12573241
8629002
8630736
16497976
11598012
|
ESR1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11029009
15569929
18450422
20664923
15496458
|
PRKCZ
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
11585925
15884057
14560023
16189514
11748077
18353613
11723139
10085094
|
CSNK2A1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
29732088
17374729
21506126
11689703
10671551
12149249
15818404
10747897
10837139
20976471
19662498
21285348
11035045
11707428
21735093
17444818
20558317
11972058
16707567
|
RET
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12600984
15994200
|
AKT1
|
BMI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22505453
23092893
|
AKT1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
20858269
23331499
20028971
11882383
21303971
17680028
20214616
22094462
17287208
17374729
20398329
21506126
21402455
12040186
19623618
12063252
18218901
|
AKT1
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20016067
23331499
17680028
20214616
17688959
20398329
16537363
17052453
19575820
|
AKT1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
18521086
26944939
11108261
17627277
20101208
17570479
15604293
23169992
26554417
16452229
15193262
7838153
12374744
11139588
26272591
11432835
20179234
11507039
9528769
|
AKT1
|
ALYREF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18562279
|
AKT1
|
POU5F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23041284
24497960
|
AKT1
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11943559
23331499
25241761
21071413
12183455
15149849
11438723
|
AKT1
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11809767
9032240
|
BMI1
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
BMI1
|
RNF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
16710298
22493164
22902369
20068231
22325352
25355358
17157253
16751658
26496610
16714294
26468281
26151332
12183370
12589020
21772249
25843776
20601937
32296183
21676867
27647897
15563468
27705803
16359901
24457600
19636380
|
PRKACA
|
AURKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
23861900
16222244
16246726
33744274
29764989
26165940
11039908
17545617
27242098
26481147
28869606
26134678
33988677
26831064
33760847
16083426
17895985
|
PRKCZ
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10962008
8702918
18667433
17646398
|
FGR
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23109003
12495636
7529876
10593973
|
CEBPD
|
CEBPB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7646815
18703634
7910803
11559710
18092000
1741402
|
ESR1
|
CEBPB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19652226
18414489
|
CEBPB
|
DUSP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18682532
18761321
|
PRKACA
|
CFTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
28003367
23060444
25867080
21455600
30600261
1716180
28242698
19328185
32102849
92316961
19095655
14602047
7530719
10581361
11053017
9385646
25330774
15657296
1377674
|
CSNK2A1
|
CFTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
21930781
17289674
|
PRKACA
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
33914026
16199882
22173096
21303971
33815677
22094462
17287208
26068882
26884171
33605402
21506126
24117889
12297048
21822311
16476742
|
PRKACA
|
GRIA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10366608
12536214
|
PRKACA
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
22266331
9891036
15193262
|
PRKACA
|
RET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20682772
15966897
17050626
11886862
|
PRKACA
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9461522
24003153
10753752
11146000
2987243
27481942
27646272
|
PRKACA
|
AQP5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
29384694
26569106
18478076
|
CSNK2A1
|
G3BP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
27022092
33065005
32302571
32302572
12642610
27083003
23163895
11604510
31171631
27920254
|
CSNK2A1
|
HNRNPC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
32.0
|
1.0
|
Omnipath
|
19651622
20058876
17081983
20166139
15687492
18691976
20068231
18452278
19664995
17693683
17287340
19413330
12564933
18669648
15302935
|
CSNK2A1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11139588
26703694
9337862
20043841
11432835
11507039
9528769
7838153
|
CSNK2A1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12700239
12432063
|
CSNK2A1
|
ARRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11877451
32863206
|
DUSP1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
9020184
18813292
8626452
9202001
11278799
|
RPS6KB1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
29128895
23242584
22114931
23460185
19925796
19112174
7838153
|
DDX17
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19995069
21182205
12738788
20348541
19718048
20663877
25604459
|
ARRB2
|
MAPK10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19782076
11090355
18408005
11356842
|
ARRB2
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
23208550
17148612
17666399
24658140
27226565
2163110
24561123
22364396
|
MAPK8
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21988832
17570479
11279232
23816567
|
NCBP2
|
METTL14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9409616
24316715
24407421
24981863
|
NCBP2
|
WTAP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9409616
24316715
24407421
24981863
|
RET
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18669648
9312068
11062067
15911620
95141073
16153436
15755722
|
MAPK8
|
CTBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
28532298
14567915
17496919
19591900
21372320
19788416
15708980
8608010
16984892
20512932
20220133
21438496
20054826
19616017
23762064
15611655
|
MAPK8
|
WWOX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15580310
12514174
18371080
|
PRMT1
|
FUS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
30354839
23152885
25192599
12183049
11850402
16169070
16713569
25810899
|
RNF2
|
RYBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
POU5F1
|
SOX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20505756
12136102
17324942
15988017
17068183
|