STAT3
|
BCL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16732314
16293640
|
BCL3
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17881446
18367518
|
SYK
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5220991
8621719
|
LYN
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5220991
8621719
|
PDGFRB
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731806
17620338
|
YES1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
CBL
|
SRC
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5219404
17141222
|
CBL
|
MET
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5215187
11894096
|
FGR
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12435267
7721825
|
CBL
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBL
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBL
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CCT3
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
24756126
1001844
|
TGFBR2
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CCT8
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MAPK1
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17205132
|
CDK1
|
PRPS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31253668
|
COPA
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
STAT3
|
CXCL12
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25453873
28072604
|
SHC3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
STAT3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731598
14966128
|
JAK2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
EGFR
|
ANXA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217387
15581623
|
EGFR
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16729043
5218694
|
EGFR
|
ANXA1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5217387
15581623
|
SH3KBP1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11894095
|
EGFR
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
1845983
|
PTK2
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19948216
10655584
|
FKBP5
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
AR
|
FKBP5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15131019
|
FXR1
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
FXR1
|
ENO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
FXR1
|
ACTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
FXR1
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
QKI
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
HNRNPK
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HNRNPK
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18413735
|
SRC
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16844778
0604705103
|
HSP90AA1
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AA1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12799359
11988487
|
HSP90AA1
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16888650
5218924
|
HSP90AA1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0908908106
19805354
|
HSP90AA1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AB1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CAD
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
RPL23
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PIK3CD
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
TRIP10
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215944
12456510
|
LYN
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11443118
11124936
|
LYN
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
LYN
|
PIK3R5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
LYN
|
HCLS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15795233
5217625
|
LYN
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
LYN
|
ELMO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15952790
23109003
|
SRC
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
MAPK1
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
AR
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14619959
20610535
|
YWHAH
|
MDM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16511560
5218386
|
NFATC4
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17242187
16489119
|
SRSF1
|
NPM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218180
16376875
|
NPM1
|
CCL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MAPK11
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
VAV2
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
CDC42
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
11804587
|
VAV2
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
PAK1
|
CTTN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
6541884
18344974
|
SYK
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
PDGFRB
|
STAT3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
17145802
17496910
|
STAT3
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17510282
20038813
|
STAT3
|
CXCR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20185584
23024284
|
STAT3
|
PTPN13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24191246
15870198
|
STAT3
|
PDGFB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7876144
8662928
|
PDGFRB
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
9484840
|
NCOA2
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19805480
16483936
|
TNF
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21887257
19287455
|
EIF4A3
|
EIF4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ETS1
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22869003
20428211
|
CXCR6
|
CXCL16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11060282
9166430
|
ACTB
|
EFNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10219243
11747816
|
BCAR1
|
ACTB
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6174726
18164686
|
SRC
|
ACTB
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7296071
19903481
|
CTTN
|
ACTB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11018051
7680654
|
ACTB
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11018051
7680654
|
JAK2
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11443118
11124936
|
CCL3
|
CXCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9312096
11470772
|
HNRNPA2B1
|
CCL21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
YES1
|
PDGFRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7685273
6730440
|
YES1
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
32296183
35044719
|
PDGFRB
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10733900
6731185
|
ZAP70
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16339550
6731727
|
CRK
|
ASAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
PDGFRB
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9546424
9739761
|
PDGFRB
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14973141
|
PDGFRB
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8657151
9484840
|
PDGFRB
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
8702949
|
PDGFB
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9546424
9739761
|
PDGFB
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15845350
12753909
|
PIK3CA
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
PIK3CB
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
SYK
|
MAPK11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12038794
8636072
|
SYK
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9720763
10592173
|
ZAP70
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5211965
10556826
|
LCK
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
LCK
|
CSK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15489916
15489910
|
ETS1
|
LCK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7970721
|
SRC
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16005629
15157149
|
TGFBR2
|
GNAO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PIK3CD
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
JAK2
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
JAK2
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
JAK2
|
PIK3CG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
JAK2
|
PIK3R5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
JAK2
|
CAMK2B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
SRC
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17570479
17158356
|
PTK2
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5221628
9285683
|
KIT
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
7520444
|
PTPN13
|
FASLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9261095
16498403
|
HSP90AB1
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CHUK
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SRC
|
ASAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SRC
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11817894
15788770
|
SRC
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16432186
0510562103
|
SRC
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6672010
16291744
|
NCOA2
|
SRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19305643
10454563
|
TRIP10
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5212318
10713100
|
CDC42
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11817894
15788770
|
CDC42
|
RPS6KB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214238
11438723
|
VAV2
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8994827
9032261
|
CDC42
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11438723
|
PDPK1
|
PRKCZ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12840507
9889098
|
PDPK1
|
YWHAH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12177059
|
EGF
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20178463
17081983
|
CXCR4
|
CXCL14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23669361
8427967
|
CXCL14
|
CXCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
32239134
28360196
|
RPS6KB1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214238
11438723
|
PRKCZ
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
18650932
7232391
|
AR
|
CDK5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23941877
20610535
|
PIK3CG
|
PRKCZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8765021
16527821
|
PRKCZ
|
NCL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9388266
16189514
|
PTPN13
|
EFNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9920925
|
MET
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10521801
16782899
|
EFNA1
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19890008
20130824
|
EPHB2
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16298995
18713744
|
PTK2
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17893324
22952866
|
GNG2
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17419683
16537363
|
MET
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10871282
10648629
|
PIK3CD
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
PIK3CA
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
PIK3CD
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
HSP90AB1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21730179
1105160108
|
HSP90AB1
|
AIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19375531
7021854
|
HNRNPA2B1
|
HNRNPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
AR
|
KHDRBS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18273831
20610535
|
NCOA2
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12588987
5216126
|
AR
|
YWHAH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19996220
8009645
|
AR
|
PIK3CB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23365759
20610535
|
RXRA
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
15650026
|
AR
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
15650026
|
HSPB1
|
ANXA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPB1
|
PRPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GNAO1
|
CXCR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15251452
5217114
|
GAB1
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8596638
|
GAB1
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8596638
|
FGR
|
ELMO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15952790
23109003
|
HNRNPA3
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SH3KBP1
|
ASAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17255943
5219572
|
CCL11
|
TPI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
QKI
|
HCLS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
PRPSAP1
|
PRPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CCL1
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11470772
10910894
|
CCL18
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23951310
32103204
|
CCR3
|
CCL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12554737
9276730
|
CCR6
|
CCL20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9169459
12149255
|
GPC1
|
TDGF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19013461
6797290
|
CCR2
|
CCL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12554737
9276730
|
CX3CR1
|
CX3CL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9024663
9390561
|
CCL25
|
CCR9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10229797
10640743
|
ACO2
|
TPI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
EFNA1
|
EPHA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
9330863
|
EFNB1
|
EPHB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
11713248
|
EGFR
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
VAV2
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
15345594
11313921
20940296
11262396
|
KIT
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
8950973
16780420
25737303
15315962
|
CDK1
|
CDK7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
20360007
11113184
16327805
|
NR1I2
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
16189514
23160820
9489701
15604093
9727070
26855179
22976785
|
BTK
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CSK
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23455922
31980649
|
CDC37
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17525741
25036637
|
CDC37
|
PDPK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25036637
31980649
|
HSPB1
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26344197
30669930
|
EGFR
|
AIP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20029029
31980649
|
EGFR
|
ACTB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22366308
31980649
|
EPHA2
|
EFNA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
7218654
19525919
|
CCR1
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
AKT3
|
FKBP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
LYN
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
9573010
|
CCL21
|
TRIP6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AKT1
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26344197
19262695
|
CSK
|
MATK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
BRAF
|
HSPB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27684187
31980649
|
RXRG
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AKT1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
PIK3CG
|
PIK3R5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
HSP90AA1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
KHDRBS1
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9346240
|
CXCR2
|
GNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
AKT1
|
GSK3B
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
15829723
|
AKT1
|
GSK3B
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
23552696
|
CBL
|
FGR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
7721825
12435267
|
CDC37
|
FKBP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25036637
24981860
|
CDK7
|
FKBP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
EGFR
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24797263
15657067
|
CCR5
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11350939
14674010
|
CCR5
|
CCL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9334377
10477718
10498628
8663314
23597562
12427015
9468473
|
CXCR2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
11170396
|
LCK
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
7208262
16107303
|
CSK
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10753943
19262695
|
CCR5
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11278738
11591716
|
ARRB2
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19202075
19122674
11877451
23242524
|
FGR
|
HCLS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10066823
|
TDGF1
|
AIP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
GNAZ
|
EPHA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AIP
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
834.0
|
0.83
|
STRING
|
36370105
|
BRAF
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
PTK2
|
YES1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
BTK
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
SRC
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
6538879
18273061
|
SRC
|
CBL
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.84
|
0.84
|
mint
|
5219404
17141222
|
FGR
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
31980649
|
CDC37
|
CDK5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21163940
23455922
33961781
9150368
|
CDC42
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31871319
28628118
28205554
|
LCK
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
25814554
10825200
18070987
|
EPHA3
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11870224
16713569
|
CRK
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
23397142
10962563
12615911
|
CSK
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15144186
31980649
12485116
|
AR
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
ARRB1
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33844281
19202075
16432186
23242524
|
TRIP6
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
16713569
14688263
|
PDPK1
|
GPC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
31980649
|
CBL
|
SLA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
ARRB2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
EGFR
|
SHC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
GSK3B
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
23455922
29568061
33961781
|
ITK
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
32707033
33961781
|
SHC2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8610109
16273093
24430869
22973453
|
SRC
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32707033
9169421
18070987
22581261
|
BCAR1
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
9020138
|
KIT
|
JAK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8611693
7527392
9355737
|
MATK
|
KIT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
7536744
9038210
|
EFNB1
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16189514
8878483
|
ETS1
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25117710
15788656
|
SRC
|
DOK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11071635
22974441
|
AKT2
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
12149249
9736715
12176337
11445557
33961781
14500673
11278835
11546794
|
DAB2
|
FGR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12473651
16713569
|
ELMO1
|
DOCK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
21930703
14737186
|
FGR
|
DOK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11071635
22974441
|
EFNA1
|
EPHA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
9195962
8070404
|
ENO1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
FKBP5
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
HNRNPK
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
CBL
|
EPHA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
MET
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
6538879
18273061
|
CBL
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11149930
19380743
|
MET
|
CBL
|
â—¼ UBIQUITINATION
|
✅
|
|
0.86
|
0.86
|
mint
|
11894096
5215187
|
LCK
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
31980649
|
LYN
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8626437
8051175
8910336
31980649
|
LCK
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
31980649
|
CD24
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22731636
8753773
|
CCR4
|
CCL22
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9743322
9933589
9430724
|
CCR4
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8573157
12270118
|
CRK
|
HSPB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22939629
31980649
|
ASAP2
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10022920
17474147
|
SRC
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17363140
15116119
10517671
15140878
|
AKT1
|
BRAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10869359
25241761
28628118
28205554
|
CCL23
|
CCR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9886417
9558365
10660125
|
CDK1
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
AKT1
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
CBL
|
VAV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
CCL5
|
CCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
RXRA
|
BCL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9812988
16713569
|
AKT1
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
BRAF
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
27034005
31980649
17979178
33961781
27684187
|
CDC37
|
AKT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
12176997
25036637
33961781
|
EGFR
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
VAV2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24797263
10938113
11516622
19531499
22973453
12454019
10618391
18271526
20940296
|
EGFR
|
ITK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
STAT3
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
22693070
|
LYN
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34079125
24728074
|
LYN
|
BTK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11226282
8058772
11598012
8629002
8630736
|
LYN
|
GAB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34079125
24728074
|
AKT1
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24886428
23397142
14749719
12138087
|
CCR5
|
CCL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9334377
10477718
9169459
11700073
9468473
|
MET
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24828152
24728074
|
ZAP70
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16713569
16189514
16339550
10419455
|
GAB1
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34079125
24728074
|
CCR3
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11449371
10733106
8642344
7622448
9289016
|
CCR1
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11449371
12270118
8530354
7545673
14637022
11116158
7622448
9115216
9289016
10910894
9336350
|
SRC
|
KIT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24728074
12878163
12444928
|
CDC37
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
PRPS1
|
PRPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
AKT1
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
NCOA2
|
RXRG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
CRK
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
EFTUD2
|
EIF4A3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CDC37
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22504172
12176997
31980649
24869908
|
JAK2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24240702
9363897
10635327
16273093
23838182
10358079
|
EGFR
|
HSPB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24189400
23397142
15657067
|
LYN
|
DOK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11071635
11825908
|
LYN
|
FGR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
32707033
31980649
|
CRKL
|
KIT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11071635
9092574
|
KIT
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9788619
24728074
|
DAB2
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12473651
16713569
|
BCAR1
|
TRIP6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11782456
16713569
14688263
|
GAB1
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
CRK
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CRKL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
LCK
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
SRC
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
CRKL
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
NCL
|
NPM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
AR
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
JAK2
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
BCAR1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
STAT3
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
PDGFRB
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
CBL
|
LCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25036637
31980649
12471035
24189400
23956138
|
CDC37
|
CDK7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8666233
33961781
29568061
26186194
|
SHC3
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22973453
9685397
8610109
16273093
8662772
9507002
|
ANXA1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20029029
15581623
31980649
24189400
|
EGFR
|
SHC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
28724758
22973453
24658140
24430869
25402006
|
EGFR
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
24658140
12522133
25402006
|
EGFR
|
FGR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
DOK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
CRKL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
24658140
25402006
18271526
25754235
16729043
23397142
|
EGFR
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
EFNA1
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14692877
7973638
8755474
19573808
20505120
8139691
22244754
19525919
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
MAPK1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
JAK2
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10925297
11294897
15156153
30413785
15284024
11350938
12626508
12576423
11940572
10918587
12244095
8626374
9211920
19834108
26775640
14551213
27351213
23838182
|
BCAR1
|
CRKL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9498705
8810278
10753828
22974441
8978305
18835194
|
GAB1
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12138161
16713569
24728074
19380743
|
CSK
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12387813
17525734
9208935
7678701
21746865
7513429
|
DAB2
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12473651
16189514
16713569
|
AKT1
|
HSPB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17510053
31980649
12740362
11042204
23397142
|
RXRA
|
TRIM24
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
EPHA4
|
EFNA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8755474
16189514
19836338
10366629
|
EGFR
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
EGFR
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
IKBKG
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
CBL
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
KHDRBS1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
20332299
|
EGFR
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
16829981
|
BCAR1
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
MAPK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8929531
10597268
12566304
|
EGFR
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27059931
7657591
8665853
27903975
15107835
24797263
28791635
9756944
23799367
23175185
28198003
12734385
14505571
20940296
19155296
10635327
15117950
22833562
29629558
12061819
8662998
10086340
33762435
11994282
20877636
32714745
25005938
31182136
19578043
7782294
24714105
10799548
23158001
26055326
33617900
23153581
15210722
25872741
15657067
19947936
10428778
18508924
16969069
17971399
15962011
19531499
25521828
23774213
22976291
31959764
22591401
18255265
15735736
16713569
20562913
17880946
16914641
9890970
22394513
16729043
32114396
17995934
17182860
18319245
18271526
17545148
15383614
25140053
32377695
15465819
33627783
8798643
25754235
15282549
26177020
22266821
16923119
17242169
30544639
12604776
11239464
9130710
19225046
11370743
21772844
16105874
18273061
7592693
23897813
17486068
16246327
23457600
32904620
12803489
31120930
15668240
22203672
23418353
20124286
28541302
33323455
10092522
14627991
15677445
15159412
20308550
16849543
12593795
19836242
9121472
19713535
18316398
11408594
|
SRC
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29899407
17094785
16713569
18273061
7782294
12941616
10829062
31120930
15135048
17141222
18996392
8635998
11994282
22203672
19861161
16636290
|
BTK
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10826882
10427990
9408950
7629518
|
ZAP70
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16503409
9407100
22266821
8798643
10779765
11353765
9988730
10074432
10078535
29053960
11133830
|
CBL
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11894096
25241761
18273061
19433454
21222362
19450681
21163258
16397241
17533376
15123609
|
CBL
|
FLT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17635922
10514377
19276253
|
CBL
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25814554
17635922
10514377
|
CCT7
|
ANXA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CDC37
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32707033
33961781
31980649
11085988
|
EGFR
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
23956138
24658140
25402006
18271526
15657067
|
SRC
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
17284441
6169640
|
ZAP70
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
22973453
24658140
16273093
25402006
|
EGFR
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20624308
24189400
21918175
24362532
10722725
23866081
26551075
|
EGFR
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16729043
9642287
31980649
10595738
22973453
24658140
11956190
16273093
9617486
25402006
12198159
8875975
9480911
|
EGFR
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
31980649
23956138
20145033
21573184
25402006
15485908
15657067
14966128
9756944
18258752
15284024
24189400
24240702
25754235
24135280
15950906
24658140
12873986
20067773
10358079
|
EGFR
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24797263
31980649
24658140
25402006
16729043
|
EGFR
|
GAB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23066441
31980649
10913131
9890893
24658140
10648629
21278788
25402006
10734310
18271526
19401591
11432805
|
EGFR
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
22973453
24658140
23764002
25402006
16799092
34079125
23866081
|
STAT3
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18367518
21590492
23504318
|
YES1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17145710
22430206
11160627
|
EGFR
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17145710
17570479
15951569
|
STAT3
|
HSP90AA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9880553
10440232
23228483
|
BCAR1
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9581808
9020138
|
LYN
|
KIT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9341198
11825908
24728074
|
LYN
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10318860
|
BRAF
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16508002
14654779
19933846
|
MAPK1
|
ALOX5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12670876
12205041
|
SH3KBP1
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
7148030
16407834
1209329
|
SRC
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
21573184
15313931
11294897
8657134
18070987
10918587
12244095
19372587
12626508
8626374
14551213
16713569
8272872
11350938
9566874
12576423
11940572
15735682
|
STAT3
|
HSPB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16527988
14715258
|
STAT3
|
HSP90AB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18266962
12559950
|
CXCR1
|
CXCL6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1840701
3260265
9164944
|
PDGFRB
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10508235
9546424
9739761
|
PDGFB
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10508235
9546424
9739761
|
DOK1
|
CRKL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11071635
11553620
9822717
25814554
|
CCL16
|
CCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
CCL16
|
CCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
PDGFB
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10508235
9546424
9739761
|
CRK
|
KIT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9092574
24728074
9233773
12878163
|
PDGFRB
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
2466336
1374684
9739761
|
PDGFRB
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
2466336
1374684
9739761
|
PDGFRB
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17496910
16189514
11172806
|
PDGFB
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
2466336
1374684
9739761
|
PDGFB
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
2466336
1374684
9739761
|
LCK
|
ZAP70
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
7961936
10556826
8798643
9685404
22242145
7539035
10318843
15144186
16461343
|
ETS1
|
TGFBR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14976186
10508522
|
JAK2
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15644415
12506011
10455108
|
CXCR4
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17158356
10506573
|
JAK2
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10925297
9553131
|
CCR5
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11449371
10477718
10488147
9334377
8663314
14637022
9207005
11116158
9289016
|
SRC
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
604342200
7033822
17038317
|
KIT
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17496910
7520444
|
KIT
|
SLA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24284075
26788993
|
AR
|
CXCL8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17617741
20610535
22040886
|
ETS1
|
CHUK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15469934
|
AKT3
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19609947
|
SRC
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24034250
20624308
9837958
24728074
|
EPHA3
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9632142
|
SRC
|
EFNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8878483
16189514
22279592
|
SRC
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25814554
22402981
|
PDPK1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
9368760
11825911
14500673
10698680
31467278
12149249
27563096
11313365
11278835
22569334
26264872
10226025
32876514
26256536
21775285
11438723
11445557
23397142
|
PDPK1
|
AKT2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9228007
9094314
15890450
|
ETS1
|
CXCR4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21741415
16840440
|
ETS1
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11857377
18181172
8934537
|
CCR5
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12429730
15660419
18632580
|
AKT1
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19713527
8524413
23824745
16009706
29464284
20856200
19995607
16123141
20682768
27563096
14645548
15688030
22337773
11035810
17428466
18505846
15470047
14701753
16282323
|
GSK3B
|
CDK5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17607942
15676027
15652488
|
NR1I2
|
PRKCZ
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19129222
|
PRKCZ
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18353613
9512493
|
PIK3R3
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25814554
22402981
|
PTK2
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25814554
22402981
|
PTK2
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11119718
10592173
7537275
|
GNG2
|
BTK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11742120
11698416
7567982
|
GNB1
|
BTK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11742120
11698416
7567982
|
AKT2
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10869359
|
RXRA
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GSK3B
|
SLA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
GSK3B
|
EFTUD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
AR
|
GSK3B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20127713
20610535
18687691
|
GSK3B
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15361837
15178691
14985354
|
PIK3CD
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11002419
10995764
10448070
|
AR
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20610535
20946682
17283128
|
TRIM24
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9115274
19909775
16713569
|
ARRB2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24069330
17353931
33961781
17620599
|
RPS6KB1
|
HSPB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19593530
|
PIK3CG
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10194437
12506011
10455108
|
GAB1
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10871282
8596638
|
AKT3
|
HSPB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19593530
|
AKT2
|
HSPB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19593530
|
NCOA2
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15657427
9430642
21478865
24561505
11514567
11851396
11981034
17947383
10748178
|
PIK3CB
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11002419
10995764
10448070
|
GAB1
|
PIK3R5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10194437
12506011
10455108
|
RXRA
|
CXCR5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14993281
|
CCR3
|
CCL11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8676064
10733106
9169459
9712872
9207005
8642344
25450766
8609214
23597562
|
MET
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11439336
|
CCL13
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10699158
23846739
|
CCR10
|
CCL27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10781587
10725696
10725697
|
CCR10
|
CCL28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10781587
10725696
10725697
|
ACTB
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
CSK
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
BCAR1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
CBL
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
EGFR
|
VAV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
FKBP5
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
AKT1
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
18191226
19122674
19262695
|
EGFR
|
SHC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
BCAR1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
CBL
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
SKAP2
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
29568343
9837776
|
PTK2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
EGFR
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
EGFR
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
AKT1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
CBL
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
PRPS1
|
PRPSAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
AKT1
|
PDPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
PAK1
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
5220560
7744004
|
CCL20
|
CCR6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
10488147
10498628
9169459
9223454
9294137
|
PIK3CA
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
PRPS2
|
PRPSAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
AKT1
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
CBL
|
SYK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
DOCK2
|
ELMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
CBL
|
LCK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
7721825
8621719
8900205
8626543
9178909
16107303
11741956
11904433
|
LYN
|
HCLS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
16713569
9104825
15795233
7682714
10066823
|
MET
|
GAB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
10871282
10913131
10995442
10734310
9242692
|
AKT1
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15998799
10358075
25241761
11500364
9381178
11994280
23085457
15722337
19667065
15784622
|
EGFR
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
16729043
5218694
|
CBL
|
LYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
7721825
12149655
9160881
18235045
8621719
7782294
12244174
15190072
33512474
32707033
|
CBL
|
EGFR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16914641
7033849
028274
|
GAB1
|
CRKL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
25241761
10871282
24728074
30480076
10753869
23397142
|
EPHB2
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10644995
9632142
18713744
|
PRPS1
|
PRPS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
25416956
25910212
26496610
32814053
33961781
26186194
22939629
|
SH3KBP1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
6170483
15090612
|
CRKL
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9162067
9129019
16982329
9590251
8621483
25814554
10907644
10608804
15107835
7545163
9092574
9195915
12244174
18835194
9311917
8524328
16503409
24886428
10657627
14604282
9820532
8662998
9461587
9851874
11399323
9344843
11157475
10204582
9660791
15556646
8978305
11553620
8626543
9988765
33961781
11263968
15358160
11133830
|
CBL
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31980649
9129019
9416834
22974441
8621483
25814554
9178909
15581361
18835194
8943292
12393469
8524328
8683103
8662998
10962563
9461587
19380743
16289966
11792427
8626543
9988765
33961781
9617486
8626404
|
EGFR
|
EGF
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
8145580
21439278
|
SRC
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31980649
8845374
21573184
25402006
7506422
10075741
19704002
10971656
23175185
10777553
22227249
20935677
20624308
21268077
17158602
24189400
9020193
16713569
22973453
11983694
24658140
28065597
21278788
17284441
7797556
20333651
7527393
10358079
|
EGFR
|
EGF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16274239
25241761
10085134
11684674
28988771
22729867
18271526
30083275
10788520
23597562
19531499
26280537
8663535
25453753
21822280
12297050
2790960
21439278
12093292
12620237
10970856
18427122
25080504
17697999
9135143
15620700
|
PAK1
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9535855
11157984
21029865
16678097
19596003
23455922
9705280
31871319
25150978
12879077
12606577
10360579
31478661
10684602
8107774
21048135
23175184
18057010
10802735
21167153
15548653
12650940
18426980
7744004
20936779
24276241
|
SRC
|
BCAR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10739664
10085298
10542110
21034468
17129785
17038317
11514617
10487518
16849545
12972425
12615911
15020686
12397603
|
CCL5
|
CCR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
CCL11
|
CCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
EFNA1
|
EPHA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
NR1I2
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
AR
|
NCOA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
CBL
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
EGF
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
NCOA2
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
CRK
|
BCAR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
31980649
9581808
22974441
15673687
10208419
12615911
10464310
15492270
12799422
18835194
8631823
10747099
11278916
16413489
10753828
16267043
10329689
19380743
10085298
14657239
27669437
17038317
9920935
11369773
11839772
|
CCT2
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT6A
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT6A
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT6A
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CDC37
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CBL
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CBL
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CDC42
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CDC37
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT7
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT8
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT7
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CHUK
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PAK1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
39.0
|
1.0
|
ACSN
|
10230394
10461188
10467124
10511705
10558990
10559936
10611223
10613909
10661401
10837486
11018042
11062502
11121431
11340065
11385609
11413130
11493700
11907067
11950587
12054568
12885870
12954615
14749719
14764585
15157156
15229651
15280015
15536084
15713627
16293614
16702231
17270021
17522712
22154077
8625410
8929531
9346240
9381178
9843499
|
AKT1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
CDK1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
12049737
14551205
15279786
17303408
17660363
18414028
18590585
21725609
7575488
|
CDK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
18071308
16166315
24677263
12965220
15907327
26287183
21858202
25618528
12049737
16009721
19124971
16403219
17498878
|
YWHAH
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21988832
11697890
8929531
9369453
17979178
|
AKT3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
23109003
12954615
22094462
10949026
15023346
17680028
18218901
17270021
|
RPS6KB1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15280015
10611223
12954615
9346240
11493700
10230394
10558990
8929531
9381178
19641507
17270021
10837486
|
PAK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
27121078
20166139
22096607
9346240
18823547
11493700
9381178
23650610
15280015
10230394
10558990
8929531
25225063
18669648
10837486
10611223
23109003
12954615
10949026
16413544
19465939
18707149
15784622
17270021
|
AKT1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
137.0
|
1.0
|
Omnipath
|
10880354
19052636
21506126
20028971
21303971
20214616
11994280
8929531
17570479
12832477
17555943
25241761
11715018
18636226
21998731
9812896
17680028
11500364
18385666
18707149
10201527
18218901
11983683
10490655
19030972
19667065
11756412
11020382
16931767
18372248
15808505
20138985
18046313
18669648
19121340
19703413
11714830
10949026
15972258
16341064
10358075
23085457
18220336
10516287
12897128
9580112
9651683
11923280
9346240
16697215
19690332
11493700
15452053
12040186
10826997
12175651
15722337
14737178
11882383
15226424
10521512
15023346
15784622
17052453
16044149
16403219
12444011
20166139
20398329
9381178
11544290
15037618
12767520
15280015
10230394
10558990
15998799
10082559
11577096
10837486
15169778
10611223
23109003
12954615
22094462
11438654
11312610
11254732
21540285
10383455
19664994
10722653
20832730
18570873
10926925
17270021
|
AKT2
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
15452053
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
12954615
22094462
10949026
11438654
17680028
10516287
18218901
17270021
|
STAT3
|
BCL3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10347215
11875494
12193690
12223527
12907458
14607900
14670306
15218058
15356132
15465827
15573129
16418395
17404308
18776941
19380816
20093776
20237412
20406969
20435894
20580461
20581311
21372296
21765015
21840487
22461508
23124025
23390297
23454751
23953057
24857661
27216177
28186502
7543512
|
BCL3
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
21.0
|
1.0
|
ACSN
|
10754326
10952726
11875494
12907458
14660645
14668329
15079071
15465827
15536066
15644117
16878026
17145890
17404308
17485448
19171876
20138012
23390297
23430059
7594497
8383323
8580069
|
BCL3
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12907458
15465827
22782967
22798670
24130828
|
HSP90AA1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
17177598
16187797
15284455
16849543
16969069
16953218
17699773
17372273
17712310
|
PIK3CD
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9590251
7537740
8995358
9259313
|
EGF
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
17177598
16187797
15284455
16849543
16969069
16953218
17699773
17372273
17712310
|
BCAR1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11353765
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
|
KIT
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11994499
16780420
12444928
17904548
|
CRK
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11353765
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
|
CRKL
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CBL
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
17177598
16187797
15284455
16849543
16969069
16953218
17699773
17372273
17712310
|
BCAR1
|
CBL
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11353765
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
|
CRKL
|
CBL
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRK
|
CBL
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11353765
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
|
CRKL
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CBL
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11353765
15169881
18835194
20189481
|
SRC
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
9525940
7782294
16713569
18273061
10829062
10799548
10934191
12604776
9890970
17570479
9013636
15135048
17094785
25784557
8635998
10092522
12522270
8621719
17141222
16636290
11239464
19861161
11994282
12941616
14739300
22203672
8849724
15212693
|
CRK
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
8683103
16289966
8626543
8621483
9617486
16713569
9416834
8524328
10962563
8626404
9367879
8662998
12393469
11792427
15581361
9013636
15581362
9178909
9988765
18835194
8943292
20697350
9129019
19380743
25814554
9461587
|
LCK
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
9525940
10829062
10799548
10934191
7721825
16107303
12604776
9890970
17570479
11904433
9178909
10092522
11997497
12522270
8621719
9102067
11239464
11994282
11741956
|
YES1
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10092522
11994282
11997497
12522270
9525940
12604776
9890970
9102067
10829062
10799548
11239464
10934191
|
SH3KBP1
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
20130058
20711168
12618476
11894095
16407834
16713569
11071869
19268472
25472714
17306257
22262777
15456872
11152963
10679202
15962011
25036637
15107835
22833562
11067845
11894096
12177062
17675467
21830225
12135478
24167568
16228008
12874286
17072306
15090612
14596919
|
SYK
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
72.0
|
1.0
|
Omnipath
|
16289966
15922744
9525940
19419964
11133830
33512474
18273061
10829062
10799548
10540342
10934191
7721825
12435267
11331248
12604776
9890970
11042121
10092522
11997497
12522270
9857068
9988765
15556646
11742985
15536084
8621719
9102067
22880054
10551821
11239464
10617633
11994282
10570266
12881521
9535867
15577829
|
CBL
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
9092574
17904548
25737303
8950973
15315962
17635922
10514377
|
CBL
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
11133830
10779765
10358158
16503409
8798643
20189481
22266821
23109003
18835194
10074432
10078535
15268851
15169881
26192618
9407100
9988730
11353765
|
CBL
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
188.0
|
1.0
|
Omnipath
|
34609770
16105874
18273061
22239438
24797263
20332299
17635922
23158001
17545148
8662998
12604776
9890970
23153581
17182860
25872741
12593795
23175185
10092522
15107835
22266821
22833562
24714105
17242169
25140053
20124286
19531499
9756944
10086340
22203672
19225046
16729043
15282549
20562913
22394513
20940296
23331499
7592693
19713535
10635327
19836242
15465819
15210722
25521828
23897813
10514377
12734385
18508924
11994282
20877636
33323455
22976291
23774213
23027125
15159412
18255265
16246327
28541302
16849543
23799367
16713569
10799548
8798643
19155296
9121472
17486068
21772844
16969069
15677445
15962011
23418353
12803489
32714745
14505571
27903975
19578043
26177020
11239464
18319245
11408594
10428778
12061819
17995934
17971399
27059931
26055326
15735736
23457600
7782294
22591401
29629558
11370743
7657591
21071413
28198003
18316398
19947936
9130710
18271526
15657067
31182136
16923119
17880946
32904620
15117950
14627991
15668240
15383614
|
CBL
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
16397241
15123609
23331499
25241761
21222362
11894096
18672314
21163258
19450681
18273061
35309168
17533376
19433454
17635922
10514377
|
CBL
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
8641358
9119889
19380743
8621719
7629144
17635922
10514377
|
CBL
|
LYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
12149655
18235045
12244174
8627181
8621719
7782294
15304502
9160881
15190072
7721825
|
GAB1
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
17177598
16187797
15284455
16849543
16953218
17646646
15329413
17712310
15118073
|
CDK7
|
CDK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
11900249
12648680
15703371
16697054
17386261
17884153
19667075
19809470
19847258
7533895
|
GSK3B
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9832503
17359287
|
CDK7
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
85.0
|
1.0
|
Omnipath
|
16565220
18767875
11113184
33657372
27303922
19690332
19667075
15703371
10913154
14988404
1532335
29793495
20360007
7799941
19158392
19664995
33574676
19809470
8548828
7533895
17386261
34489572
26881937
17554681
20068231
18452278
21900495
18669648
12814430
16327805
18691976
15868411
8441405
21778139
25849598
27908669
12459251
1833185
19651622
22263797
19847258
19707596
17924679
20347419
29435156
18220336
34370741
19369195
22505032
21468563
17884153
12663041
22425727
7944411
12648680
11900249
8344251
16697054
31429764
24970150
|
CDK1
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
17081983
15208671
15070696
15798205
17570479
18669648
15774499
12935893
12586835
12555062
15809305
12740386
11279232
9271440
15235105
12036952
11914378
11872747
14993219
11705993
16964243
|
CDK1
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10383391
17570479
12032153
|
CDK1
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15735705
|
CDK1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
26573794
12569365
22275373
25704883
17043241
23321516
9725910
24480624
21799006
24424504
28062857
21820033
25950519
28415597
27450452
25691442
21782001
|
CDK1
|
NPM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
49.0
|
1.0
|
Omnipath
|
17081983
12058066
27253419
22285574
25908633
20333249
16912078
27553022
19933706
16083285
20068231
27619510
17570479
18669648
7213797
81161106
26536659
11278991
17287340
17924679
15190079
14670079
|
CDK1
|
KHDRBS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9315091
|
CDK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17145710
31980649
8360196
23956138
15901825
28150246
18271526
15657067
24658140
25402006
15302935
|
CDK7
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
10734072
24424504
25943391
21820033
21157430
28638477
|
CDK7
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20725631
15494306
|
CXCL12
|
CXCR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15261139
15882617
17035340
20535745
20644254
21521526
22025564
23034983
23402812
23567181
24277834
|
CXCL12
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15261139
15882617
17035340
20535745
20644254
21521526
22025564
23034983
23402812
23567181
24277834
|
CXCL12
|
CXCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
24023874
10233851
10699158
11859124
22633458
18648536
18448868
8752280
30476826
12714578
16725153
9712844
8752281
9551924
21757744
19837984
25495026
26582643
16626895
|
EGF
|
EGFR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
15003992
15175028
15466195
15958574
18423981
19631971
20430953
21098712
8101258
|
AR
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15305378
19318561
21613411
19258514
15650253
17242169
18692155
15288768
11556855
20610535
|
SRC
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
232.0
|
1.0
|
Omnipath
|
16414009
17081983
25958313
16943190
15618223
19935697
19305428
25402006
24797263
29285309
7488034
15592458
17389395
16461772
20562096
19275932
17897439
15899872
17570479
2803273
23636329
23246962
25505586
23175185
15615697
23349873
16849545
25356505
11983694
24189400
11756413
25748412
26325669
26150526
14512423
18789131
14750954
31978707
25573954
27495374
20071362
18707149
28759036
16729043
26494466
27716204
25537504
17237269
18687633
25884760
29036202
26936397
17575160
20926745
20935677
15282306
23702846
15476828
9069259
19336574
20421302
15660394
23866081
19377510
9777370
22426783
29321659
33706413
25841779
19840943
18669648
12397069
16843263
18957516
34088769
25077442
14963038
19836242
17653080
19625610
16936701
11960379
15548697
18295415
17523611
21268077
20333651
21399647
23376850
11250711
23942551
19704002
22927910
11160627
31952541
10777553
17016520
2543678
19258037
33883672
17646646
28102297
23873690
26771606
21573184
23119029
19151764
16713569
7797556
25955608
15302935
20407013
28513565
23119185
9990038
21080693
20190765
25347738
14630916
15708852
21822308
20628053
25301722
24658140
19690143
27564112
20802523
29124875
33657368
12101233
21787862
14764607
17284441
12878163
26290602
15951569
16543144
15212693
17971399
14523024
10971656
21278788
8845374
22430206
18083107
29641465
18234969
18460189
17551925
22957061
26571308
17043637
20371672
10358079
16799092
19154417
23066441
28065597
12842895
18180459
17158602
18271526
15657067
25159151
34367939
24919575
10075741
25366117
24349301
17561374
16862179
20215522
31980649
24335899
16037379
18451158
14530278
16505275
12063263
23449029
11311660
|
MAPK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
12556561
1651322
17081983
3138233
15901825
1939237
91332050
2543683
2115882
17192257
1651323
15302935
|
LYN
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17145710
31980649
16799092
23866081
24658140
11160627
23764002
25402006
22430206
|
MAPK11
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15187187
18039929
12738796
16932740
11274345
|
AR
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18358509
12534934
22260327
15288768
18951974
|
JAK2
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17389395
10635327
17081983
10358079
16273093
16799092
18691976
10459005
9363897
15284024
23838182
17016520
18669648
15302935
|
EGF
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
131.0
|
1.0
|
Omnipath
|
17145710
17081983
21822280
20813200
23613900
9135143
25453753
21303971
10209155
26821125
12297050
27387652
25241761
30083275
12093292
30197274
21649524
19531499
18762250
16729043
26921391
17697999
17575160
21722395
12620237
19129184
10788520
23331499
3494473
15620700
14568001
15958209
24096486
18253097
16843263
18320059
21532939
10085134
22260327
15708576
26280537
23912460
21858221
11116185
10970856
27462018
18427122
25080504
20953304
19135477
11684674
8639530
27564112
18270696
2790960
17971399
23185569
19895983
28988771
29617357
23597562
19531623
23950932
21071413
8663535
6289330
16274239
17563729
21439278
20458382
22216880
18271526
12771140
21311755
24709886
25366117
12648462
21107857
|
FGR
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
31980649
24658140
11160627
25402006
|
EGFR
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
19901323
15231819
16497976
25402006
17389395
20068231
23066441
11432805
9658397
19509291
18669648
10978177
10753869
10734310
11896055
18271526
24658140
10648629
11779868
31980649
15212693
9890893
17016520
|
EGFR
|
SHC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
24212772
9507002
16273093
11791173
8760305
8662772
|
EGFR
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
31980649
23397142
18271526
24658140
25402006
16729043
|
EGFR
|
ANXA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
15581623
31980649
3020049
24782913
2457390
24189400
9223619
17081983
20029029
16052208
22792315
24103589
|
EGFR
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
52.0
|
1.0
|
Omnipath
|
10595738
9480991
16273093
9617486
25402006
17399949
8662907
8875975
21602891
20068231
8194526
12198159
9642287
11956190
24658140
26656091
9480911
31980649
15212693
26473374
16729043
17016520
|
EGFR
|
VAV2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17389395
19531499
11516622
26910843
10938113
10618391
12577067
12454019
17016520
|
EGFR
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
17496910
31980649
25241761
16273093
24658140
25402006
|
EGFR
|
SHC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
11350724
16273093
8760305
|
EGFR
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16713569
16919435
25402006
10806474
29435030
20473329
7657702
19339212
17496910
15657067
24658140
19625610
7529872
20802513
31980649
10545505
24043698
15951569
|
EGFR
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
23956138
12070153
20145033
14967450
20032199
21573184
25402006
10358079
23894143
14966128
24135280
25241761
14963038
24189400
15657067
24658140
15485908
15950906
18258752
31980649
9756944
22693070
12873986
15951569
15284024
|
SRC
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24457997
28957431
26788993
|
SLA
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
24457997
7543898
|
EFNA1
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
8139691
20505120
23331499
11248553
14692877
24003208
7973638
8755474
18988627
15114347
9576626
22244754
9330863
19573808
11114742
19525919
|
AR
|
FKBP5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15821585
19433513
20048054
21809344
11867260
16210365
20610535
17142810
|
SRC
|
HNRNPK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
7516469
17178840
24642125
12052863
7592945
16854432
16713569
21184736
|
HNRNPK
|
KHDRBS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
21988832
22365833
31413325
16713569
12370808
|
HSP90AA1
|
GAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
17177598
16187797
15284455
16849543
16953218
17646646
15329413
17712310
15118073
|
STAT3
|
HSP90AA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18266962
16189514
12559950
|
HSP90AA1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
1525041
19805354
20048054
15861399
17974989
26342197
17353003
26196320
16713569
27903893
1540595
21157430
19706771
|
HSP90AA1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19356729
18266962
10995457
25714412
16189514
12176997
12586360
15843522
|
HSP90AA1
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
1310678
16844778
16189514
18266962
|
IKBKG
|
CHUK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
IKBKG
|
CHUK
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11340079
12133805
12799363
15199157
15485931
16818229
17363905
17485448
17693255
18716620
20138012
20300203
20531300
21217011
22435554
23430059
28462531
|
TNF
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
TNF
|
IKBKG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
AKT1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20837477
20098747
17660512
|
IKBKG
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
17145710
17485448
16938294
11865184
11877453
16970925
22435554
17244613
17568778
17363905
16818229
15084594
15485931
24369075
20300203
21217011
12799363
23180781
14743216
16319058
21703539
19666608
20098747
12612076
16126728
15218526
23430059
9751060
20138012
18716620
20368414
10837071
25355947
15836773
23109003
20531300
17702576
17363973
15214841
12459277
17561400
21640763
16285893
28462531
12709429
10968790
15199157
26192618
12133805
16497931
11864612
17693255
17072322
11340079
|
MATK
|
LYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
19651622
19901323
9171348
18691976
15626731
17575268
28958480
14985335
20068231
18452278
1722201
18070987
26212012
29050963
16497976
8612628
20564182
18669648
|
CSK
|
LYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
19901323
11489946
15626731
10415030
16497976
14967142
16537894
7935444
20068231
18452278
10592173
18669648
9171348
18691976
8612628
8794770
19651622
22711887
1722201
|
LYN
|
SLAMF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15315965
15212693
11806999
|
LYN
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
9820500
24129562
10022120
18818202
21469132
24607955
18083107
17389395
19285079
11536198
10592173
25045209
7797565
11380624
9857068
7513017
30923129
8621719
10477689
7831290
15701717
27258042
19369195
28082678
8666899
9535867
8657103
14871838
|
LYN
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
9581808
9020138
10428862
|
LYN
|
HCLS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
8578591
9104825
9183008
10066823
17570479
96108162
16713569
23001182
15795233
7682714
|
LYN
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9169439
11369622
11389892
12590707
23109003
15728464
9148935
12495636
10753828
25814554
7529876
10593973
|
LYN
|
DOK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11071635
11489946
16537894
11841937
11825908
|
LYN
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
24728074
11825908
9341198
17570479
|
LYN
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
18083107
8629002
12573241
11598012
19369195
10051622
9012831
8630736
9730885
10811866
9052864
8058772
11226282
|
NPM1
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
31434245
22955283
12748172
16009132
|
ETS1
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
8552081
10358095
20534573
11782450
15572696
|
PRKCZ
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11035106
12942541
23109003
12900386
15721486
|
MAPK1
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21494553
21449613
25241761
16045329
23991633
20361728
11570862
22521293
11948414
|
MAPK1
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
8506364
7499846
8618896
15967991
8226850
8626561
|
MAPK1
|
CAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10659854
12438317
15890648
|
MAPK1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16039586
28646232
18451303
|
MAPK1
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
12054624
15547943
20080742
14967450
12040186
15173823
12697810
11940578
7545671
16227978
21035469
12738796
16039586
9722592
17255949
15774499
15187187
19541618
19091303
19565474
17052211
19085255
11279232
9271440
18039929
18775330
11705993
10601235
12792650
11431469
|
MAPK1
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
59.0
|
1.0
|
Omnipath
|
18448488
19413330
11335711
9343414
15465816
25584415
12576423
11350938
20068231
12681450
12763138
9872331
11780390
18491316
18669648
11404481
10521505
18691976
20058876
15979846
14551213
10446219
|
MAPK1
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10537323
21079800
17570479
22514278
20444238
|
MAPK1
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
10377179
17604322
12048211
|
MAPK1
|
NFATC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15657420
|
MAPK1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19604315
15542607
16964243
15212693
11604394
|
MAPK1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
14654779
21478863
19541618
16508002
19710016
19933846
15664191
29335436
8621729
|
MAPK1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18511414
9725910
10318905
|
MAPK1
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12008033
26538579
15379552
10593929
|
MAPK1
|
ARRB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
19651622
19153083
18767875
17322306
15456867
10347142
20068231
19413330
9388255
|
MAPK1
|
KHDRBS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18691976
12478298
19664995
20068231
|
AKT1
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16163388
18356162
16511560
|
PAK1
|
CTTN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
12453877
16854367
9683637
24859002
20444238
|
PDPK1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
11134074
21726627
21209852
10995762
23885116
26009991
26238471
10551809
25335797
|
AKT1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11435472
14749719
24886428
14585966
23397142
9032240
12138087
|
CDK5
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
20058876
17114649
12176333
12950086
19298660
19664994
12176334
15542607
19413330
23537649
19036346
19664995
21825040
11604394
|
CDC42
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
17145710
810774
10360579
21167153
8107774
10559936
9705280
12650940
16678097
23331499
21029865
10684602
18057010
15020669
21070974
11340065
21048135
15003621
20936779
10934474
11413130
15788770
15713627
9535855
23109003
11950587
19628037
7744004
12879077
12606577
24276241
10224076
19596003
8973630
19812368
11248548
10802735
18719708
10613909
10461188
23455922
|
PAK1
|
GNAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10531372
9166747
7559455
8429024
|
PAK1
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
30562756
24859002
12453877
18344974
29152154
21079800
26490115
27135389
16854367
20444238
|
PAK1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17192257
15710605
10205168
25733387
|
KIT
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
23073628
15790786
11369651
15007386
12481435
15526160
28403213
10358045
28192400
17546049
9355737
|
STAT3
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
STAT3
|
CDK5
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
JAK2
|
STAT3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
11867689
14610620
19833085
20237318
20406969
20581311
21840487
22754783
24091328
27216177
7512720
7521688
|
FLT3
|
STAT3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10477595
14670306
15253381
16418395
25215878
8920882
9268501
|
STAT3
|
CXCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10347215
11875494
12193690
12223527
12907458
14607900
14670306
15218058
15356132
15465827
15573129
16418395
17404308
18776941
19380816
20093776
20237412
20406969
20435894
20580461
20581311
21372296
21765015
21840487
22461508
23124025
23390297
23454751
23953057
24857661
27216177
28186502
7543512
|
STAT3
|
CXCR4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10347215
11875494
12193690
12223527
12907458
14607900
14670306
15218058
15356132
15465827
15573129
16418395
17404308
18776941
19380816
20093776
20237412
20406969
20435894
20580461
20581311
21372296
21765015
21840487
22461508
23124025
23390297
23454751
23953057
24857661
27216177
28186502
7543512
|
STAT3
|
CCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10347215
11875494
12193690
12223527
12907458
14607900
14670306
15218058
15356132
15465827
15573129
16418395
17404308
18776941
19380816
20093776
20237412
20406969
20435894
20580461
20581311
21372296
21765015
21840487
22461508
23124025
23390297
23454751
23953057
24857661
27216177
28186502
7543512
|
STAT3
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
24429361
19741199
17710228
19736311
12488502
20493732
19404962
|
SYK
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10777558
25416956
21516116
20133729
31515488
16189514
10825200
32296183
|
SRC
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
19901323
10918587
9305919
8272872
29036202
9344858
12626508
10815799
16497976
15592455
16713569
17389395
12576423
11350938
9484840
11294897
28978186
18070987
12244095
27472461
21690253
23928694
22303479
8657134
11404481
9083098
14963038
8626374
17016520
9566874
10982829
15212693
11940572
11429593
14551213
15037656
15313931
11850821
9154828
9582023
|
LCK
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11404481
9484840
9344858
18070987
10815799
16189514
10825200
25814554
|
JAK2
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
167.0
|
1.0
|
Omnipath
|
10918587
8272872
16319070
18718905
15592455
34066153
23166634
33986510
17389395
29162862
29449694
33512408
21098725
9083098
17565041
27748760
27344175
34031055
29290793
21285325
33846242
33774038
9566874
25962054
20826784
14551213
26188635
26008966
15284024
26175413
21481791
33774344
26307676
9305919
10925297
15615703
12626508
16497976
32087696
16469875
31914141
23331499
11350938
28978186
16306356
33824475
18988627
17401459
19147545
15151905
12637586
34433042
8626374
15950906
27181202
24793791
20455003
21575192
32094172
15322111
17016520
34247191
19901323
12626585
27086926
21166956
23906537
31976162
9211920
12576423
22306293
10207096
12075083
11294897
26787900
12244095
14701810
33909625
11803465
17360477
28827891
33820781
19159681
18939995
11445068
27941883
11429593
30054295
26675255
11850821
9582023
34067421
34707127
15786731
25986861
27351213
34118143
15077188
26699492
12595539
21071413
18498667
22153071
15156153
33513694
25915428
11940572
12529382
18525315
24501689
33839684
24316223
19834108
9575217
|
CDK5
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
25038288
16651438
19156541
12763138
28114390
16879821
23941877
15096606
26198700
|
TNF
|
CXCL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10925299
11112697
11438547
11875494
12646658
12811837
1431106
14607933
14625680
15099563
15699106
16713974
17916596
18633355
19411070
20038811
20184663
20435894
21133840
21411734
21826665
22595692
22955274
23170255
23430059
23508573
23510023
23567181
23769623
24092389
24378531
26201938
8910423
|
JAK2
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
35.0
|
1.0
|
ACSN
|
11306493
11867689
12754507
1439146
14610620
15099563
15356132
15573129
18209571
18555777
18555778
19581928
19833085
20138012
20406969
21115385
21840487
23034983
23567181
24011634
24091328
24346288
24418198
25002027
25582338
26201938
26268945
27216177
27557510
7512720
7521688
7543512
7590867
8837607
9845545
|
TNF
|
CCR2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
34.0
|
1.0
|
ACSN
|
10623817
10925299
11112697
11438547
11875494
12646658
12811837
1431106
14607933
14625680
15099563
15699106
16713974
17916596
18633355
19411070
20038811
20184663
20435894
21133840
21411734
21826665
22595692
22955274
23170255
23430059
23508573
23510023
23567181
23769623
24092389
24378531
26201938
8910423
|
ETS1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12509451
10913190
9780181
7896795
16199883
|
RPS6KB1
|
CAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23429703
25061101
|
CCL2
|
CCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
10623817
15032599
17681149
19915063
23527025
23567181
23943801
24531940
27216177
|
CCL2
|
CCR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
10623817
15032599
17681149
19915063
23527025
23567181
23943801
24531940
27216177
|
TGFBR2
|
CCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
44.0
|
1.0
|
ACSN
|
11279127
11792802
12809600
14557817
15003992
15099563
15265520
15653932
16127449
16424049
16474430
16572188
17070508
17404308
17768418
17934056
17979848
18423981
18490733
19038247
19109155
19732719
19747910
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
22703233
22874531
23034983
23784029
24132110
24336330
26201938
26966341
2871107
7594497
8515656
|
CCL2
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
10770925
10488147
10699158
22633458
9169459
11470772
28389721
9336350
8530354
15629146
11310855
9276730
20219869
9115216
9346309
9312096
9837883
10529171
15207250
9287323
12554737
7759884
|
CCL2
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9364936
10706668
|
CCL2
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8631787
7679328
76793288631787
9115216
10699158
|
CCL2
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8642344
|
CCL2
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10477718
16298345
1629834510477710
|
CCL2
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17160712
16421945
|
CXCL8
|
CXCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555778
18633355
18980965
21328342
21847358
24406209
25922287
26201938
26548401
27557510
|
CXCL8
|
CXCR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555778
18633355
18980965
21328342
21847358
24406209
25922287
26201938
26548401
27557510
|
CXCL2
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8702798
9260277
16189514
1379593
12964882
|
CXCL6
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8702798
10699158
9485196
16189514
9692902
22633458
12964882
10593335
|
CXCL5
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8702798
10699158
16189514
9692902
12964882
9485196
|
CXCL8
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
8702798
8137938
9195914
10699158
1840701
12628493
10188995
15946947
22262769
8550564
9553055
1379593
8662882
8245475
10368283
9485196
8940121
15282370
11350788
9725262
10206993
|
CXCL1
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8702798
9195914
10699158
16189514
1379593
12964882
|
CXCL3
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
129648828702798
8702798
16189514
12964882
|
CXCL1
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
7592830
8702798
9195914
10699158
12628493
22633458
10188995
12549928
8550564
28389721
16189514
1379593
8662882
9126332
10216072
24218476
8940121
|
CXCL16
|
CXCR6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
11017100
14625285
11290797
22633458
|
ACTB
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
24914801
15507212
16439214
22608513
|
SRF
|
ACTB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18804439
15837932
1762920
9571041
|
CXCL5
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8702798
10699158
16189514
9692902
22633458
9485196
|
MET
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
10871282
12138161
11146548
10753869
10618718
|
CRK
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
CRKL
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRK
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
CRKL
|
BCAR1
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRK
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
CRKL
|
BCAR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
BCAR1
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8978305
9498705
18835194
10592173
8810278
10753828
12345678
8943292
23770091
|
GAB1
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10753869
25241761
24728074
31585087
10871282
10592173
23397142
|
CRKL
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10753869
25241761
24728074
31585087
10871282
10592173
23397142
|
CRKL
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8978305
9498705
18835194
10592173
8810278
10753828
12345678
8943292
23770091
|
TGFBR2
|
CCL3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
44.0
|
1.0
|
ACSN
|
11279127
11792802
12809600
14557817
15003992
15099563
15265520
15653932
16127449
16424049
16474430
16572188
17070508
17404308
17768418
17934056
17979848
18423981
18490733
19038247
19109155
19732719
19747910
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
22703233
22874531
23034983
23784029
24132110
24336330
26201938
26966341
2871107
7594497
8515656
|
CCL3
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
11170631
10734056
10488147
10699158
7545673
10202040
22633458
10498628
9169459
9336350
10910894
8530354
23765404
9687537
9207005
20219869
9115216
9624164
10660125
7622448
12381680
|
CCL3
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8573157
|
CCL3
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24218476
7594543
7622448
|
CCL3
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
11170631
16298345
10477718
23765404
15075201
9468473
20219869
9169459
11700073
10699158
9334377
9790730
22633458
12964882
|
CXCL9
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11110785
22633458
|
CCL4
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
7594543
12381680
10699158
7545673
10910894
8530354
|
CCL4
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7622448
|
CCL4
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
10498628
16298345
8663314
10477718
9468473
20219869
23597562
10699158
9334377
9790730
16467191
22633458
12427015
12964882
|
CCL19
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10706668
|
CSK
|
YES1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
11489946
16537894
19369195
18691976
7690925
12640114
15592455
18083107
14967142
16439366
|
YES1
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11369622
12558988
16293639
12590707
25868388
15728464
25416956
32296183
10753828
23397142
|
YES1
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11071635
|
CCL22
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9933589
9430724
29637711
10699158
22633458
9743322
|
CCL17
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10498628
10488147
9169459
9430724
29637711
10699158
9169480
10540332
22633458
|
CCL5
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8573157
12270118
|
CXCL8
|
CXCR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555777
18555778
18633355
18980965
21328342
21847358
23869868
24406209
25922287
26201938
27557510
|
CXCL8
|
CXCR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555777
18555778
18633355
18980965
21328342
21847358
23869868
24406209
25922287
26201938
27557510
|
CXCL6
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8702798
9485196
16189514
9692902
22633458
12964882
10593335
|
CXCL3
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8702798
10699158
16189514
22633458
|
CXCL2
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8940121
8702798
9260277
8550564
10699158
16189514
1379593
22633458
10188995
12964882
|
CXCL8
|
CXCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
70.0
|
1.0
|
Omnipath
|
7592830
8702798
22904195
9195914
10699158
7559482
12628493
23597562
10188995
15946947
8626516
8550564
9553055
1379593
8662882
19190236
8245475
9126332
10216072
1891716
9485196
8940121
15282370
9464567
11350788
11511101
9725262
10206993
|
CCL16
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
11470772
|
CCL16
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
22633458
11470772
|
CCL16
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11470772
22633458
10910894
|
CRK
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
11146654
11353765
12094222
12432077
14697347
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
9808620
|
CRK
|
BCAR1
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
11146654
11353765
12094222
12432077
14697347
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
9808620
|
EPHA3
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
21071413
16713569
18988627
11870224
|
PDGFRB
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
19426560
10733900
16713569
27686861
|
BCAR1
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
9920935
11369773
11278916
15673687
8662907
9581808
8631823
8070403
10747099
12065577
10329689
16267043
10592173
10208419
17038317
18835194
20627867
16413489
10753828
8943292
9860979
11839772
14657239
12799422
19380743
15492270
10085298
12615911
|
CRK
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
24728074
20619534
12138161
19380743
11146548
10592173
19350053
16713569
10618718
|
CRK
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
25814554
35044719
19380743
|
CRK
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
7561682
25814554
12370821
20068231
11602246
10085298
12615911
7509446
7529876
17016520
11314030
|
PDGFB
|
PDGFRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
ACSN
|
15099563
17145802
17496910
18633355
24359404
|
PDGFB
|
PDGFRB
|
â—¼ SHARES_COMPLEX
|
|
|
5.0
|
1.0
|
ACSN
|
15099563
17145802
17496910
18633355
24359404
|
PDGFD
|
PDGFRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
1520781114514730
23331499
15207811
21098708
14514732
15207812
28267575
|
PDGFB
|
PDGFRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9739761
20577048
30150707
16189514
15207812
28267575
7679113
11297552
15207811
20534510
17981115
10806482
285049611903042
11903042
11331882
2850496
|
PDGFRB
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15489898
18315570
16189514
9010229
2173144
|
PDGFRB
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10806474
20802513
16713569
|
PDGFB
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
7685273
9488729
10508235
9739761
|
SYK
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12456653
9341187
9705962
19372136
11071869
11449366
11909947
9697839
21822214
|
SRC
|
SYK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
7513017
17353363
17570479
16189514
9389695
23100514
|
SYK
|
HCLS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
16782030
8578591
15795233
21444687
9104825
9183008
25723543
15166239
23001182
96108162
18587398
|
SYK
|
FGR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11672534
15536084
|
SYK
|
VAV2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15345594
11262396
10592173
10749872
|
SYK
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9169439
9342235
16189514
|
SYK
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
27758765
8636079
25241761
10438543
16189514
28306714
11389697
|
SYK
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
8798764
19664994
15536084
8621719
8798676
16497976
25990959
7518561
8845015
16189514
7539035
15659558
|
SYK
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
18083107
8629002
28368423
11598012
28359287
29455639
19369195
10051622
9012831
8630736
28088788
11226282
|
LCK
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
LCK
|
ITK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10652356
12731048
12740575
17544292
19290918
20814939
21127503
22513334
23620508
3263576
8478617
8986721
9438848
9738502
9751747
|
CSK
|
LCK
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
7.0
|
1.0
|
ACSN
|
10790433
11181701
12485116
15713798
19290918
8011291
8986721
|
CSK
|
LCK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
56.0
|
1.0
|
Omnipath
|
20346773
19901323
10692391
11489946
22566970
24463463
2141684
16497976
15592455
20813252
10799545
14967142
27547268
24764511
28522807
16537894
12485116
8193535
24227778
17897955
8183556
22426112
89123626
15489916
14610046
23109003
18691976
28448599
17947241
1639064
12414720
15144186
27460989
24816556
22507872
8631775
15743820
25979654
8945479
11181701
27045023
25595912
15259016
|
LCK
|
ITK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
21747996
28516764
19132916
23109003
20305788
23982207
15771581
19690332
28644030
15144186
9312162
12842872
17192257
23946894
|
LCK
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
110.0
|
1.0
|
Omnipath
|
23874979
7961936
17579062
29073235
30992398
15292262
23933134
31932281
21829558
15592455
21917715
9199177
8798643
7612267
16339550
23331499
10202147
22238573
16189514
32184287
21103055
7642520
33531381
12648457
12522270
17998387
9685404
20945976
16839418
15144186
16461343
16094384
11270871
17192257
10037717
8756661
19606965
23758320
27869819
16111633
25137454
15268851
17942891
33482200
11514606
11514605
15659558
10556826
10318843
|
LCK
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11369622
12590707
15728464
9257837
10753828
|
LCK
|
SLAMF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11806999
|
LCK
|
DOK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16537894
10799545
11841937
11489946
|
LCK
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17570479
9788619
24728074
|
LCK
|
VAV2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11516622
12400014
17570479
12454019
|
DAB2
|
CSK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
16713569
12473651
|
CSK
|
FGR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
11489946
7515063
16537894
8612628
14967142
|
CSK
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
55.0
|
1.0
|
Omnipath
|
11489946
23051580
20657842
20337577
7592628
23824743
21940449
26453921
22323292
14665621
17525734
14967142
3103926
23159740
16227616
1383688
12387813
20525307
10698938
7525268
19534553
16537894
26234813
10592173
12468645
7513429
24632723
7687537
21442427
22689825
25372749
11007774
9208935
18614016
28974561
21632985
19369195
17855352
7678701
23378895
9523754
|
CSK
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18823558
21829547
9890993
27803182
21062671
7529872
21709741
|
TGFBR2
|
CCL5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
44.0
|
1.0
|
ACSN
|
11279127
11792802
12809600
14557817
15003992
15099563
15265520
15653932
16127449
16424049
16474430
16572188
17070508
17404308
17768418
17934056
17979848
18423981
18490733
19038247
19109155
19732719
19747910
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
22703233
22874531
23034983
23784029
24132110
24336330
26201938
26966341
2871107
7594497
8515656
|
TGFBR2
|
EGF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
41.0
|
1.0
|
ACSN
|
11279127
11792802
12809600
14557817
15003992
15099563
15265520
15653932
16424049
16474430
16572188
17070508
17768418
17934056
17979848
18423981
18490733
19038247
19109155
19747910
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
22703233
22874531
23034983
23784029
24132110
24336330
26201938
26966341
2871107
7594497
8515656
|
DAB2
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
16713569
11387212
|
SRC
|
JAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11476890
12094222
16919435
17496910
17517963
25572304
26552706
27216177
|
KIT
|
JAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8611693
7527392
15526160
9355737
|
JAK2
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9670957
|
CCL5
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10734056
7622448
8642344
22633458
10733106
10699158
9289016
|
CCL5
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
10734056
7622448
14637022
22633458
9115216
9624164
10699158
11116158
12270118
7545673
9289016
9336350
10910894
8530354
|
CCL5
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
16298345
10488147
28381538
10699158
22633458
9289016
12213786
8663314
11449371
10318947
12964882
25923671
9207005
23480650
11116158
10477718
14637022
9334377
9790730
|
CCL26
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
16102831
10488147
15207250
10699158
16339911
22633458
|
CCL26
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15207250
12689946
22633458
|
CCL26
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
15039444
|
CCL26
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22633458
29637711
15039444
|
CCL26
|
CX3CR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22633458
20974991
29637711
|
BCAR1
|
ZYX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
15308668
15688067
16000375
18287025
18829532
18835194
22043013
29021139
9819392
|
BCAR1
|
ZYX
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
15308668
15688067
16000375
18287025
18829532
18835194
22043013
29021139
9819392
|
SRC
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
19901323
24962474
11514617
8670206
15316024
20927395
8070403
17389395
12480533
22710723
30422386
25976166
17570479
21963850
12972425
20103658
17129785
10487518
15817476
21301050
10739664
17038317
21765460
17016520
12397603
15212693
15020686
10542110
23457577
10085298
12615911
15272013
21034468
11604500
|
PTK2
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
8649427
7479864
12135674
15673687
8810278
9038154
8670206
9285683
11604500
11119718
12480533
24939893
8621540
11577104
9360968
9148935
10592173
12119061
12972425
9360983
10092764
21855630
10753828
11839772
18233957
10545505
12615911
8662921
11514617
|
PRKCZ
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
11447289
19615955
16488589
6321473
8321321
12845332
11313945
12040186
19568798
15567848
14585353
|
MATK
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
7536744
10022833
9038210
|
SRC
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12878163
7520444
10523831
|
KIT
|
DOK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11071635
11825908
|
PTPN13
|
FASLG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
5.0
|
1.0
|
ACSN
|
12702723
12724420
16498403
23069999
9184224
|
ETS1
|
FASLG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20617570
11970950
|
AKT2
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19609947
12048203
10485710
|
AKT1
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
15710601
12048203
25241761
19442713
11278366
10485711
15800029
19609947
17570479
17660512
18515365
19088076
10485710
|
SRC
|
CHUK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17145710
12707358
|
CXCL10
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11110785
22633458
|
RPS6KB1
|
EIF4B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
17053147
25220053
19339977
16286006
20647036
17664694
11108711
19413330
19664995
15507151
16083285
20068231
16763566
18423201
22579465
29494492
21233202
19720745
12713446
15071500
29547541
23317821
22253885
19651622
15905173
17924679
16404421
18707149
20832730
29301334
17052453
15212693
|
AKT1
|
EIF4B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18836482
17570479
25749412
|
SRC
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
12682286
15314172
20861220
18657504
11689445
12431978
25587652
11044445
22266855
11029403
11029009
|
SRC
|
CDC42
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11476890
12094222
16919435
17496910
17517963
25572304
26552706
27216177
|
SRC
|
PTK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
11476890
12531888
16919435
17496910
17517963
20027185
25572304
26552706
27216177
8892616
|
SRC
|
VAV2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17686471
8986718
11007481
10395673
9099726
|
AR
|
SRC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19305643
10454563
18687691
17108144
17079466
|
EPHB2
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
18713744
10644995
9632142
|
PRKCZ
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
10527887
11447289
19615955
16488589
6321473
8321321
12845332
11313945
16189514
12040186
19568798
15567848
14585353
|
CDK5
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
10544291
12801906
19369195
18691976
9271228
21442427
27169346
17192257
29196663
19415658
7488156
|
EGF
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23349873
19481075
15845350
22927910
27462789
|
SRC
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
14506284
26816343
9626657
|
SRC
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12750372
10592173
17275257
10830300
|
SRC
|
ARRB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17456469
17456551
16432186
|
SRC
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
28144231
15062576
20570899
25133482
21318111
11032808
25950519
21512132
17525795
12933816
20383201
24728074
24948875
24868554
25547388
19117998
21956655
17045208
15027889
24859991
15466214
26829214
21886458
|
SRC
|
PDPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
20643654
14585963
16314505
11481331
15212693
12738763
1148133
15302935
|
SRC
|
TRIP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
16880273
21689746
15988003
14688263
23576104
17591779
27134758
16713569
20876301
|
SRC
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
216.0
|
1.0
|
Omnipath
|
27351421
23242524
16254240
12370821
21940449
26142360
17525734
10593973
14604860
17389395
19171305
22402981
19339212
22353809
9748249
8941336
17570479
12464388
25226367
15611085
15817476
25241761
26393679
27978555
26833789
11927607
17828307
25913180
26866924
15247219
10085298
12387730
19055942
9507031
21454698
10973994
32814053
21057587
27931517
27438371
18793427
19695571
15735019
18560762
10592173
25319025
24389213
21852560
26689988
14984767
7505391
19568240
20103658
20822514
25868388
23275294
28423510
23764511
19625610
15561106
17192257
19138410
19369195
17088251
12753909
28701735
29190494
17016520
15598735
18814847
11821402
11418135
15728464
16291744
25067788
11602246
16713569
22287273
9032297
7997267
12960434
11369622
20616959
26079101
19534553
10931187
22710722
20068231
25866790
21347260
9822703
28202937
16153436
11980671
21855630
19826415
18464795
7529876
20621036
9330873
21473875
9425168
28956212
12615911
15951569
25814554
12876384
17438336
15212693
16966330
20705914
20847951
23729178
20407018
12558988
25127991
25918719
12590707
16360410
8054685
18814027
11696015
22800863
17117420
12495636
11278488
9864370
21776383
18083107
22814579
22194915
20515733
11119718
9148935
10428489
15743500
20655298
23065768
28213315
26923073
24015220
17289681
12110680
22006118
24164353
23109003
18935208
10753828
18233957
8816475
25118939
19664994
25530216
16760434
9330875
21266176
21034468
|
SRC
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
26706435
15574420
19881549
12941962
21442024
12808090
|
SRC
|
HSP90AB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17855507
|
SRC
|
VAV2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1531699
23118862
23457577
17570479
1311423
|
SRC
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
24728074
24034250
9837958
17570479
|
SRC
|
ENO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8578591
7629021
15592455
15951569
96108162
15212693
24841372
|
SRC
|
ANXA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
24103589
17570479
2457390
|
SRC
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10322133
23331499
15140878
|
SRC
|
CTTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
70.0
|
1.0
|
Omnipath
|
27603901
22823952
7680654
9748248
28522963
19419567
19690332
16497976
15592455
19413330
25077552
17389395
19534553
20068231
28769876
17570479
20708589
19273217
18491316
18669648
16162656
25682866
12522270
18088087
22761768
26142315
17287340
27009365
10921917
9683637
24465712
27758765
24675741
12601080
18707149
16212419
15169891
7519605
17016520
11389697
|
SRC
|
KHDRBS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9038356
10467411
8766817
22745667
7537265
7516469
11960376
10635328
1374686
18606683
16169070
16713569
1545818
15190072
|
SRC
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11445557
25241761
23242524
18283331
12600984
|
SRC
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
19109164
23170196
8629002
29455639
10051622
8630736
26165234
9052864
|
ZAP70
|
VAV2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10562324
10925299
11353765
11438547
11875494
12415267
12731048
12811837
15735648
16713974
17371980
20435894
20814939
21059766
23414611
23508573
23620508
23886063
24378531
7600293
8478617
8642247
9625766
9738502
|
VAV2
|
CDC42
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
10934226
11080163
11262396
12094222
14623913
15365099
15886116
9822605
|
CDC42
|
PRKCZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23109003
17353362
10733591
10873802
|
PDPK1
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11687500
11747822
12670391
15802604
17680028
18802401
19109239
19122654
|
PDPK1
|
PRKCZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
12887331
14500673
11222751
18691976
10075713
20332120
9768361
9748166
17335005
10357815
16189514
11141077
16051884
11781095
10764742
14604996
|
PDPK1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
15743829
15191648
10679787
23331499
19203586
15718470
26491696
26937223
9374542
24169049
15890450
28589878
9512493
12048203
10822383
12434148
20059950
11134526
|
PDPK1
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9512493
12162751
10208883
23603119
19203586
15718470
|
PDPK1
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
70.0
|
1.0
|
Omnipath
|
17081983
12429015
15208671
18326039
16286006
11438723
21561857
18802401
19864428
16099428
7545671
7489717
27149630
15388791
12183455
10601311
9465032
26582459
29257917
12967624
24604594
15718470
9427642
10209156
23769967
12586835
15809305
9218810
11500365
14560963
9271440
20932932
12370290
11914378
11684675
17680028
14993219
19570988
9445476
|
PDPK1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
156.0
|
1.0
|
Omnipath
|
15505410
12538620
12176337
19951971
24352480
11752451
19401591
11369519
10698680
10601311
15718470
24950409
20481595
24169049
10570282
16798838
14993273
11500365
9368760
19844585
17680028
7637810
9169478
26256536
7722458
9094314
12750173
11438723
18802401
9252186
23331499
18456494
9104825
10592173
16189514
20361045
18988627
11278835
20163786
20333297
20041157
12808134
19602588
8630736
10207050
11241670
10438924
9868760
25912234
20153221
25582703
11445557
21775285
12149249
14666721
18596232
9512493
23397142
11809791
12167717
21798082
16033886
10679787
16787925
29562639
15550174
21071413
8978681
10833263
19203586
10226025
26937223
14500673
20161206
11136732
11825911
11042193
9642236
22569334
18662999
9736715
12242303
11313365
11598012
11134526
|
ITK
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
12445832
12573241
8629002
8630736
16497976
11598012
|
AR
|
EGF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18511414
8580999
7522959
15590903
14662770
18692155
17374439
18212060
20610535
|
CAMK2B
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
12475968
|
CXCR4
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11668182
|
AR
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20589722
11278645
17896924
18687691
22740037
12621049
12063252
22970326
|
PRKCZ
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
11585925
15884057
14560023
16189514
11748077
18353613
11723139
10085094
|
PIK3CA
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
25793261
19117013
21041639
24950409
21816939
|
AKT1
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
19651622
20058876
14688280
11510412
25241761
20230923
20068231
18452278
11410590
17570479
10869359
18669648
|
AKT1
|
HSPB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
12740362
11042204
19593530
22983196
17510053
23397142
|
AKT1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
99.0
|
1.0
|
Omnipath
|
17428466
15207235
17145710
12052830
10729337
8250835
11756412
11923280
16914735
17623045
16697215
8524413
12054501
20398329
18372248
21506126
20028971
12040186
15808505
16543730
20138985
23331499
21303971
16009706
10385618
20214616
23180781
9373175
16039586
15829723
18988627
16282323
11577096
11035810
18669648
18216173
15169778
12851486
16123141
11882383
23109003
9065430
18691976
22094462
10949026
22710759
11715018
12459251
18636226
17192257
11254732
11278246
20858269
9812896
9582355
15023346
17680028
19369195
7945242
12900420
23552696
18387957
10722653
20832730
18570873
12147701
18505846
17052453
17693255
18218901
|
AKT1
|
S1PR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11583630
17570479
25588843
|
AKT1
|
ZYX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17572661
|
AKT1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
9736715
12149249
11278835
|
AKT1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17470458
18349820
29861848
16210317
21601007
17570479
11404460
22155408
12621049
14555644
11156376
|
AKT1
|
YWHAH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
AKT1
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11943559
23331499
25241761
21071413
12183455
15149849
11438723
|
CDK5
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
11160818
21825040
21378178
14712065
25525271
24091658
17096371
33999101
23294285
24121667
33981002
17185424
28361970
12941275
20519501
|
CDK5
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
27917404
22014572
22275373
27902483
25982277
17043241
33932081
33038264
33974920
32846021
25851605
21799006
24424504
29423094
30414425
25691442
7565807
33994848
|
PRKCZ
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
15075332
11447289
19615955
16488589
6321473
8321321
12845332
11313945
12040186
19568798
15567848
14585353
|
PRKCZ
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18353303
14657655
11481324
|
PRKCZ
|
EPHB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
11447289
19615955
16488589
6321473
8321321
12845332
11313945
12040186
19568798
15567848
14585353
|
PRKCZ
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9512493
25241761
12162751
9305920
|
PTPN13
|
TRIP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
10826496
17591779
10400701
16713569
|
FLT3
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
19805105
21827948
9918857
19438505
31066629
11027663
|
MET
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
15611085
29435030
30134553
22188814
24043698
16782899
14572662
15247219
15561106
20802513
15598735
|
FGR
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
32051585
27790061
12590707
28692661
14610060
15728464
12495636
28377405
10593973
16510472
11369622
14603053
26710849
9148935
20160475
29743287
24608426
12408869
14572662
24655477
26530902
34237080
11438458
12659633
26068982
15126359
14978737
18676832
27270311
12023386
11331870
15800067
23109003
7597091
33674746
8051157
11891289
22761432
19962670
20180147
24858039
11035755
10753828
11857088
15611137
7529876
15389641
33715263
15077193
17234784
8824286
34161758
10821872
12754219
12087088
15316068
22751010
32049010
12531888
12387730
|
GNB1
|
GNG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
GNB1
|
GNG2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23739333
8636150
9789084
10339615
12606627
15889144
15782186
11294873
18611381
10696571
19376773
12782285
19168127
|
GNG2
|
GNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23739333
8636150
9789084
10339615
12606627
15889144
15782186
11294873
18611381
10696571
19376773
12782285
19168127
|
GAB1
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11043767
8596638
11278704
10194437
10592173
|
PIK3R3
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8596638
22402981
9415396
11733063
26496610
25814554
|
PIK3CA
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
15854902
19225151
20097763
21123297
30021155
24990947
20068231
19079619
15809305
20599721
14623952
11279232
34518212
33800846
18669648
|
YWHAH
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8085158
8085159
10931830
7744815
8668348
|
AKT3
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10869359
18451171
11293329
19493313
|
RPS6KB1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
17053147
21233202
8250835
15905173
19339977
19720745
16286006
12713446
20647036
20832730
18423201
11108711
17052453
|
AKT3
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
12851486
15023346
21303971
11882383
17680028
9065430
23109003
20214616
22094462
23552696
20398329
21506126
20028971
12040186
18218901
|
AKT2
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
17145710
21303971
11882383
17680028
9065430
20214616
22094462
23552696
12434148
20398329
21506126
26051358
16293724
20028971
12040186
9712142
18218901
|
AR
|
PRPS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20610535
|
NCOA2
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
9717843
12588987
15684378
14593076
24239470
15563469
18780293
12810069
16713569
10601285
14966121
10935543
10454556
|
HSPB1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19767773
17974989
|
RXRA
|
NCOA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11387316
12815072
10334992
16908160
11870371
10334993
16541101
|
NCOA2
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
12612084
11981034
15657427
23331499
21071413
9430642
10748178
11514567
18988627
11851396
17947383
|
MET
|
GAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
10978177
17389395
19901323
10753869
15574420
15212693
10913131
10734310
11896055
20068231
10995442
9890893
16497976
14685170
17016520
18669648
11779868
|
PIK3R3
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8596638
22402981
11733063
25814554
|
FGR
|
HCLS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8578591
8611520
9104825
9183008
10066823
96108162
|
CCL13
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10477718
9790730
|
CCL3L1
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
11170631
10364178
10477718
16298345
11734558
11449371
11700073
9790730
22633458
12964882
|
CCL8
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10477718
9468473
10699158
9790730
22633458
12964882
|
CCL14
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16298345
20483925
22633458
11085751
12964882
|
CCL11
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10477718
9468473
10699158
9790730
11264152
22633458
12964882
|
NR1I2
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
9727070
15604093
11706036
9489701
16189514
26855179
23160820
22976785
|
EFNA1
|
EPHA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
23331499
24003208
9267020
15114347
9576626
8755474
11519828
11114742
18988627
9330863
|
EFNA1
|
EPHA3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
23331499
93308638070404
24003208
21071413
15114347
9576626
8070404
9195962
11114742
18988627
9330863
|
EFNA1
|
EPHA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
24003208
15114347
9576626
8755474
11114742
16189514
10366629
9330863
19836338
|
CCL11
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
15207250
9276730
9115216
9195948
11264152
22633458
12554737
12149192
|
CCL11
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
10488147
10699158
22633458
12218106
23597562
25450766
12149192
16102831
8642344
9169459
9005985
16339911
8676064
9276730
9207005
24702154
9712872
10733106
10706854
12761559
8609214
10854442
|
CCL15
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10699158
9346309
|
CCL8
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10699158
22633458
9115216
|
CCL23
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9886417
9558365
12381680
10699158
10660125
22633458
|
CCL3L1
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11170631
11449371
12381680
9115216
9624164
7545673
10202040
10660125
22633458
8530354
|
CCL14
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9687537
9548457
15905581
12381680
20483925
9346309
9405404
24218476
22633458
11085751
|
CCL8
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10699158
9005985
|
CCL28
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10975800
22633458
12964882
|
CCL3L1
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11449371
7594543
22633458
|
CCL15
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10699158
9346309
|
CCL13
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9276730
10733106
9005985
10699158
16339911
22633458
12149192
|
CCL14
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9548457
9346309
11085751
|
CCL18
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
10640766
29637711
23999500
24218476
22633458
23951310
|
EFNB1
|
EPHB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
24003208
8878483
15114347
9576626
11114742
93308638878483
9330863
|
EFNB1
|
EPHB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
10669731
23331499
24003208
9267020
15114347
11114742
12223469
11713248
9330863
|
CCL20
|
CCR6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
10498628
9223454
10488147
9169459
9294137
10699158
12081481
24218476
22633458
12964882
|
CCL8
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9115216
10699158
9195948
22633458
12554737
12149192
|
CCL13
|
CCR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9276730
10699158
24890717
9195948
22633458
12554737
12149192
|
CCL27
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10781587
11821900
12718728
10725697
22633458
|
CCL28
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10975800
10781587
22633458
|
CXCL13
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10706668
|
CCL25
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10706668
|
CX3CL1
|
CX3CR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
9390561
10488147
14607932
10699158
28389721
11432858
16189514
22633458
9931005
|
CXCL13
|
CXCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
22913878
9486651
9463416
10699158
28389721
22633458
|
CCL25
|
CCR9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10498628
10699158
11159507
22633458
10229797
|