Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
XRCC4 CSNK2A1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15385968 5217205
AHR HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2153080 18805402
AHR AIP â—¼   COLOCALIZATION 2.0 0.8 intact 6594475 16257957
HTR6 AIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
HSP90AB1 AIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19375531 7021854
AIP TFF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21984905
AIP ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21984905
ARNT ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17991765
AURKB BIRC5 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
BIRC5 UCHL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 CCDC120 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ERBB2 FER â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ESR1 SGK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084382 18414489
ESR1 GREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11103799
ESR1 TFF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 6593703
FGFR3 PPARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEK8 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HTR6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7214551 17189269
FYN HTR6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7214551 17189269
HTR6 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12650852 31160049
SRC HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16844778 0604705103
HSP90AA1 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKG NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PHLPP1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24530606
STIP1 PTGES3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21183720 16403413
PTPN11 SRC â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
SRC YES1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
XRCC4 AIP â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
CSK21 AIP â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12361709 22113938
CSK21 CDC37 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15082798 16335536 12930845
UCHL1 HS90A â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 18635949 32120844 18550537
PTN18 AIP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27880917 28675297
TEBP AHR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 11013261 11259606
HS90A ARNT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11013261 14764593
FGFR3 HS90B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939624 21487019
FGR HS90B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939624 31980649
NEUR4 AIP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEUR4 SUGT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CC120 AIP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PRA17 PRA10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PRA17 AIP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PRA10 AIP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EGFR AIP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
CFTR CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CDC37 ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 24189400
STIP1 CFTR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20534503 31324722
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
STIP1 ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 31980649
ERBB2 INSRR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 30898150
HSP90AB1 NR3C1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
PHLPP1 SUGT1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HSP90AA1 SRC â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CDC37 RAF1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
FGR HS90A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22939624 8043579 31980649
AGO1 HS90B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 17932509
TDGF1 AIP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FER EGFR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 7623846 18271526
AIP HSP90AA1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
CFTR HS90B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
AURKB SUGT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 32707033
BLK CDC37 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
IRAK1 CDC37 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15647277 32707033
FGR CDC37 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
ERBB2 FGFR4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30898150 28205554 28628118
PTPN11 ERBB2 â—¼   DEPHOSPHORYLATION ✅ - 0.84 0.84 Signor 32024694
CDK13 HS90A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 32707033
HS90A BLK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22939624 32707033 31980649
HS90A IRAK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15647277 32707033
HS90A CLK3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 22939624 32707033
HS90A ARAF â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22939624 32707033 29777862 31980649
HS90A AURKB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26186194 29568061 28514442 22939624 32707033 23443559
ARAF HS90B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25036637 31980649 22939624 32707033 29777862
SUGT1 HS90B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18818696 16501598
FYN HS90B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28514442 22939624 32707033 31980649
CDK13 HS90B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 32707033
GRK6 HS90B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19996089 22939624 32707033
AURKB HS90B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31586073 26186194 29568061 28514442 22939624 32707033 23443559
BLK HS90B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22939624 32707033 31980649
HS90B SRC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28215707 32707033 31980649
HS90B CLK3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28514442 22939624 32707033
ULK3 AIP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 32707033
CDC37 FER â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25036637 32707033
CSK21 SRC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21075308 31980649
TEBP ARNT â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11879970 11259606
HS90A FYN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 31980649 32814053 16888650 28514442 22939624 32707033
TSSK6 HS90B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 22939624 32707033 15870294
RET AIP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32062451 19366855
EGFR STIP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20029029
ESR1 PTGES3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
EGFR PTN18 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
AIP TEBP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25036637 11259606 20661446 11013261
ARAF RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 34017080 20130576 31980649
CDC37 DDR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24189400 22057045
EGFR NTRK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
EGFR RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
ILK RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 23455922 26496610
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
IKBKG IRAK1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AHR AIP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
PTN18 ERBB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25081058 14660651
CDK9 HS90A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 20305087 25036637 23455922 27684187 26186194 28514442 22939624 32707033
CDK9 AIP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 26186194 28514442 32707033
CDC37 ARAF â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25036637 31980649 24189400 32707033 29777862
CDC37 AURKB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25036637 31586073 26186194 29568061 32707033
RAF1 CDC37 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25036637 31980649 16335536 24292678 24189400 17979178 32707033 16611982
CDK9 CDC37 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 20305087 25036637 23455922 24981860 27684187 26186194 28514442 24189400 32707033
CDC37 CLK3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 24189400 32707033
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
NTRK2 FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 9648856
IRAK1 IRF7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15767370 21903422
SRC RET â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 32062451 10070972 16189514
AHR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
TEBP ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18388150 27483141 10207098 9222609
RAF1 HS90A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16093354 25036637 28537252 15618521 23118896 8962087 17699868 20039095 16330544 16335536 28146421 16504566 24462205 22939624 32707033 20159553 16189514 17409432 31980649 27703006 19011619 8408024
HS90A ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18388150 23912458 17699868 9222609 15538384 21503962 22939624 20353944 16037132 19805454 27483141 23403292 11911945 12962497 9115298
HS90A SUGT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18818696 27249023 14761955 22869522 16501598 19875381 17435760 17466273
HS90A SRC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16844778 22315411 31980649 28537252 1310678 32707033 16189514
CDK9 HS90B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17643375 23455922 33961781 27684187 26186194 28514442 22939624 32707033
RAF1 HS90B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34017080 31980649 16330544 22939624 17979178 32707033
AIP HS90B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19375531 21170051 28634279 25036637
HS90B ERBB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20650008 28369073 22939624 24189400
AIP ARNT â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9111057 12065584 11259606
EGFR CDC37 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25036637 31980649 23956138 24189400 12471035
UCHL1 EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32494592 32042339 31980649 20029029
EGFR FGR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR HSP90AB1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EPHA8 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10498895 16189514 16713569
SRC FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16966330 31980649 28514442 19711372 9169421
RAF1 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7517401 16189514 16713569
ERBB2 SRC â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CSK21 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19740745 2492519 22113938 16335536 7794926 22824801
TEBP HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25036637 8114727 27353360 22729780 23022381 16403413 19875381 10811660 16289154 20039095 14761955 18172314 22806877 22504172 19996313 15916966 16565516 14987994 11447118 22315411 18285346 10642522 26151834 21988832 9817749 20159553 11812147 19740745 26804907 11413142 12077419 20661446 20048054
TEBP HS90B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25036637 18285346 21183720 17010336 10543959 21988832
PPARA HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12482853 16189514 12962497
EGFR HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 23956138 20029029 12006493 25402006 16849543 16024644 24189400 12471035 32669362
ERBB2 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 26804907 17239458 22315411 18655187 24658140 23995768 21503962 24189400 20558745 11071886 12006493 20159553 22939624 16144943 21812426
EGFR HS90B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15657067 24658140 31980649 24189400 23956138 25402006 20029029 22939624 12471035
AHR AIP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9447995 18805402 17329248
HSP90AA1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14614132 15894266 15218035
CDC37 SRC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 32707033 31980649 11085988
PPM1A CDK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18829461
ILK CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18252715
YES1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 22430206 11160627
SRC ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 19704002 21075308 7542762 7797556 19372587 29720121 11940572 17875712
SRC ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17043237 17284441 17400812 15604093 11032808 17921256 18451880 15020686 12736255 11564893 23065768 10454579 20935677 17363140 16957778 14963108 11013076 29720121 15784253 24498420 17627277 12630920 22328528 14766010 24051437 7539106 27420286 15140878
ESR1 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21737465 21947652 22878616
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
ESR1 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25303530 18414489
STIP1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21170051 27353360
SRC RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7517401 8876196 17097642 16189514 10205168
PTGES3 STIP1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ERBB2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CDC37 CDK9 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
HS90A AIP â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 11013261 21170051 20661446 25036637
FYN CDC37 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 25036637 31980649 28514442 32707033
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
HSP90AA1 NR3C1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
STIP1 HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ - 0.92 0.92 Signor 27353360
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
AURKB BIRC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ERBB2 PTPN11 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HSP90AA1 RAF1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
FYN YES1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
HSP90AB1 PTGES3 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
ARNT SIM2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
AHR HS90A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10617682 7961671 18806268 8089152 9390191 11013261 9083006
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
HSP90AB1 SUGT1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CDC37 HS90A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21871133 25036637 33961781 27353360 22729780 26496610 19875381 12930845 9685350 15647277 16335536 25486457 24462205 22504172 22939624 22315411 12176997 20159553 24292678 24189400 21360678 26804907 15001580 11413142 21745565 14718169 16611982
CDC37 HS90B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28215707 25036637 33961781 26496610 11036079 22939624 23428871 27339980 24189400 25486457
AIP AHR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10986286 11013261 16257957 7961671 16582008 9837941 9111057 9083006 12065584
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
HSP90AB1 STIP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
AHR ARNT â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
HS90A HS90B â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 31536960 25036637 33961781 26344197 26496610 20353823 19875381 22863883 21360678
HSP90AA1 STIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
HSP90AA1 PTGES3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
STIP1 HS90A â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 25036637 27353360 22729780 26496610 21235734 20704274 19875381 24462205 22504172 19996313 10786835 18285346 22315411 10642522 20159553 28514442 21360678 26804907 11877417 11413142 21170051 24949977 9452498
HS90B STIP1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 25036637 18285346 26344197 22939629 21170051 28514442
ARNT AHR â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 10619402 33961781 7628454 11768231 19390533 22138065 10395741 26350169 20006590 10617682 31675361 11259609 23477502 17392787 12139968 9887096 8631989 28514442 9704006 8065341 18096572 8621524 7488247 8619634 11025203 10671489 11551916 8384309 12024042 19380484
HSP90AA1 SUGT1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
AIP AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 9111057 10986286 11013261 16257957 9083006 16582008 12065584 9837941 7961671
HSP90AA1 AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9083006 9390191 7961671 8089152
ARNT AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8621524 8384309 9887096 20006590 10395741 18096572 12024042 7628454 9704006 19380484 17823304 11259609 19390533 22138065 8631989 8619634 8065341 11768231 7488247
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335
SRC ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9020159
SIM2 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14701734 11782478 9271372 9020169
CSNK2A1 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16129408 18669648
BIRC5 AURKB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
BIRC5 AURKB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 23955284 21554500 16291752 18477699 12419797 27332895 19357306 14610074 20807437 17457057 29371939 17099693 11516652 24571573 17681274 21051298 19995937 16769825 20430883
FBXO11 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 31743519 22113614
BLK EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 31980649 16273093 24658140 11160627 25402006
CSNK2A1 CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 26755559 18566753 20068231 15082798 18922470 19413330 12930845 27105117
SRC CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19802004
CSNK2A1 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21930781 17289674
SRC CLEC7A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 16341139 10779524 20193029 15845454 21525931
CSNK2A1 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 19651622 11535131 17081983 8247525 8018564 18691976 9115440 20068231 18452278 19413330 7735324
CSNK2A1 PTGES3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17081983 15040786 18088087 18166671 16094384
CSNK2A1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15822905 17081983 16565220 18088087 29854279 2492519 34359868 25995454 1956339 16094384 15581363 18591256 16964243 92065884 15302935
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
FGR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 31980649 24658140 11160627 25402006
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
PTPN11 ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9756944 16273093 16729043 32024694
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
ERBB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16769082 19617202 11940572 12753909 21075308 7542762
ESR1 GREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23403292 25303530 21984905 23056300 20068169 22359603 21907792 18414489 17666587
ESR1 TFF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21984905 19858291 11517191 18543253 19935720 17317669 22382029 18414489 17938209 19462000 18322535 22093877 16219765 19933843 16087863 15541729 10037443 22543272 16651411 20422012 23874775
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
SRC FLT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16076871 12881528 20431062 18083107
FYN PTPN11 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10591186 10648627 12218089 12731048 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
NTRK2 FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 16713569 9648856
FYN PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10212213 11157475 16713569
PPARA HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 12482853 12962497
PTGES3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16565516 10642522 11447118 26804907 15916966 11413142 16403413 21988832 11812147 19875381 19740745 14761955 12077419 10811660 20039095 22806877 25036637 20048054 19996313 18285346 20661446 22315411 23022381 18172314 20159553 22729780 22504172 16289154 9817749 14987994 8114727
STIP1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 10642522 21235734 21360678 26804907 11413142 24949977 19875381 10786835 20704274 21170051 26496610 27353360 25036637 19996313 9452498 18285346 24462205 22315411 20159553 22729780 22504172 11877417
HSP90AA1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1310678 16844778 16189514 18266962
HSP90AA1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 16131566 8089152 10903152 26804907 31467278 8645634 15916966 24949977 21511880 19875381 9334248 12093808 16189514 20195357 24462205 10066374 14987994 8898375 8621522 8139547
HSP90AA1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 25036637 19011619 16093354 8962087 18266962 8408024 23118896 22939624 24462205 16189514 17699868 20039095 16504566 20159553 17409432 16330544 15618521
SRC HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17855507
IRAK1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11583588 21220427 18180283 17997719
IRAK1 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15767370 17457343 21903422
TAOK2 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10660600 23331499 21614932 12738796 11274345 18855897
NR3C2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NR3C1 NR3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
PTPN11 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18757826 18482983 10698938 17974954 14687660 24632723 20308328
SRC RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7692235 12551923 7517401 17097642 15258589 9689060 16189514 16630891 10998357 11376654 29063113 8876196 10205168 28846113 12952943 22592532 11134016 15710605 16170185
SRC RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11713247 17570479 16189514 10070972
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368