Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CTNNB1 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20571031 12200448
JUN CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20711235 20697347
CCN2 FN1 â—¼   COLOCALIZATION 2.0 0.8 intact 16457822 5218313
GSK3B CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
GSK3B SMO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15803137 23331499
PXN PARVA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18508764 18940607
IQGAP1 PXN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15263019 22573807
PXN FN1 â—¼   COLOCALIZATION 2.0 0.8 intact 21985969 8208414
JUN MBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20720108 11226757
GRB2 ATP5F1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MARS1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212831 10913161
DCTN3 ACTR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
ARHGEF6 PARVB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15005707 12499396
MAPK1 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
SMO ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15618519 23074268
ARRB1 SMO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15618519
CREB1 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9926942 6548521
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
CFTR CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12208510 5215704
JUN CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18196534 17922191
CCDC47 SEC61A1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCT2 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT5 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRKACA CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT7 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT7 PSMB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PPP5C CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
LONP1 CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CDC37 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NCK2 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12810700 12215529
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
PRKACA CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
GRB2 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
CFTR RHOQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15546864 11162552
MAPK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
CREB1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10775268
CTNNB1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
RUVBL1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18087039 0710343105
XPO1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19940019 18573912
DDB1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15558022 16291872
CTNNB1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21772333 19213727
CTNNB1 PPARD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11943708 17724465
CTNNB1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16219695
PARP1 DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
GEMIN4 DDX20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10725331 5212337
HSP90AA1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSP90AB1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
DNAJA1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 DNAJA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
GRB2 DNAJA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
DNAJA2 HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
FOS EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21239258 1918021
FOS EDN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9588211 16716598
HSPA2 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
FASN EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HSP90AA1 FASN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
FKBP4 FKBP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 27462449 11751894
SMO FKBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
FN1 ITGB1 â—¼   COLOCALIZATION 2.0 0.8 intact 21985969 8208414
PIK3CA FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOS MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
FOS HSPH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20188076
FOS RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10085083 15068801
RIPK3 GLUD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19632174 19498109
PIK3CA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 PPP1R12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RBBP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SSBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IPO7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RUVBL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RUVBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBA4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IQGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
HSP90AA1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 RIPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
HSP90AB1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP5C HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSPA8 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 PTGES3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21183720 16403413
JUN HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 20566634
ITGB3 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12372433
ILK PDPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313365
IQGAP1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
POSTN ITGB1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 20096135 22158103
VTN ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7716514 32196115
SPP1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7592829 32196115
JUN MAPK8 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
LMNB1 LMNA â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TUBA4A MAGED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PARP1 MAPK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
MTOR PDPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
MYO1D RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RHOQ PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9799731
PDPK1 RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12783890 10753910
PPARD PDPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14748722 16581799
PRKACA PLN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 22707725 21108950
PPP1R14A PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15124925
PPP1R12A RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SOS1 RANBP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12147692 14684163
TUBB4A RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SDCBP RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
TIMM50 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL2 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARVB PXN â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
ACTR1A DCTN3 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
ARHGEF6 PAK1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HSPA2 HSPA8 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HNRNPL HNRNPM â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ILK PARVA â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ILK PXN â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
ILK RSU1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
VRK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20936779 31871319
ARMC6 SCO2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
ARRB1 ELMO2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RIPK4 CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26972000 29435596
CFTR CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CDC37 PDPK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 31980649
CFTR COPB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CFTR SFXN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
CFTR FKBP8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CFTR IPO7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
CFTR DCTN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CFTR DPM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
ILK NUP93 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23455922 17353931
PARP1 JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 24636898
RRP8 NOC2L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PPARD RXRB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15604093 22205725
PPARD RXRG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15604093 22205725
SUGT1 RSU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
RXRG RXRA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBL PINX1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DNAJA2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
RHOA MAPK8 â—¼   PHYSICAL_INTERACTION ✅ + 0.82 0.82 Signor 8824197
CANX DDOST â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
LIMS1 PARVB â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
SRPRB VRK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDC37 FKBP5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
RHOJ CDC42 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10967094 31871319
GRB2 ELMO2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 21706016 31980649
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
RSU1 PARVB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HSP90AB1 UNC45A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
FKBP4 MTOR â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
FKBP5 MTOR â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ATP2A2 PLN â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
PARP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 34079125 26831064 25252691
FKBP5 ILK â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25036637 32707033
GRB2 HSPB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31980649 12577067
LMNA PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 25948554 30419336 22412018
NCK2 SOS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10026169 16713569
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ILK LIMS1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CTNNB1 RUVBL1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CTNNB1 RUVBL2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
GSK3B CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 16293724
CCT3 CCT5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PUF60 SRRM2 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CCT5 CCT7 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
GSK3B CDC37 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29568061 23455922 33961781
CFTR HSPB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29924966 23155000 26618866 17110338 26627832
CFTR COPG1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR LMNB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR XPO1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
ILK DDB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23455922 32707033 17353931
SH2B3 GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8649391 16189514 8995445
NCK2 ILK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10022929 16189514 16713569
MAPK8 JUN â—¼   PHOSPHORYLATION ✅ 0.85 0.85 mint 7148309 19527717
CCT5 CCT8 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
ACTR1A DCTN3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CCT2 CCT3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
ILK ACACA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23455922 17353931
AURKA BRCA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22110403 26831064 14990569
RIPK3 CDC37 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 21903422
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
IRS4 GRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9553137 21706016
ILK MMS19 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23455922 17353931
CHEK1 DDB1 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CACYBP CTNNB1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT2 CCT7 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
JUN MAPK1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
NUP205 NUP93 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ITGB1 PXN â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DDX20 GEMIN4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
CFTR HSPA8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CCT2 CCT8 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PARVA RSU1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PARVB RSU1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
FN1 ITGB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PARVA PARVB â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CASP8 RIPK3 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CFTR LMNA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26618866 29924966 17110338 31324722
DCTN1 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8955163 16189514
ILK HSPB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25852190 17353931
NACA JUN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25609649 9488446
DNAJA2 HSPA8 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
GEMIN4 PSMB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
HSPA8 HSPH1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
DNAJA1 HSPA8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CDH1 CTNNA1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
FKBP4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
ILK DPM1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25852190 23455922 17353931
ILK FANCI â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23455922 32707033 17353931
PPARD RXRA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15888456 34081964 19756148 22205725 15604093
CCT6A CCT7 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
LMNA LMNB1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
DCTN1 DCTN3 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CCT6A CCT8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
MAPK1 ATP1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15069082 14976217
CCN2 FN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16457822
RXRA GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MTOR GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B RSU1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B DCTN3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PAK1 ARHGEF6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ARHGEF6 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15649357 15306850 25241761
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
PPP1CA AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11039908 11551964
RBBP7 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11394910 10220405 11746496 16713569
JUN BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25609649 12080089 16713569
CDC37 MTOR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDC37 DCTN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ILK CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18252715
HSPA8 CFTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 FKBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18635947 15381148 15159550
FN1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18624398 19738201
FOS PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10535756 1331087 1663213
ITGB3 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12005431 9566877 7997267
IRS4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9553137 15316024
HSPA8 MAPK8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPARD ILK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19935699 14748722 16581799
ILKAP ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11331582
ILK MYL12B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278951
PRKACA ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17615294
NCK2 LIMS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10022929 9843575 15721255 10574708 16713569 16189514
LMNB1 LMNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21346760 32814053 25948554 11792809 31467278 34079125 19727227 24623722 30419336 21988832 22412018 26524528 26264872 29568061 16189514 29997244 30021884
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
PDPK1 XPO7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PIK3CA SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
TWIST1 POSTN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12210745 20804746 18353304
ACTR1A DCTN1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT3 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT2 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
GRB2 SOS1 â—¼   RELOCALIZATION ✅ + 0.9 0.9 Signor 23452850
MAPK1 MBP â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CCT5 CCT6A â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
LIMS1 PARVA â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HSP90AA1 UNC45A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
PARK2 RHOT1 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
ILK RSU1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
COPB2 COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
CDC42 IQGAP1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
NCK2 PAK1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
RHOA TUBA4A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CCT3 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
ILK PARVB â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CCT7 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
HSP90AB1 PTGES3 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
IQGAP1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5221163 8798539
CDC42 IQGAP1 â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 18809683
JUN FOSB â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 25609649 29020630 33961781
PARVA LIMS1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 12432066 11331308 26186194 28514442
RHOJ PAK1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 31871319 32814053 10967094 28514442 14521508
DCTN1 DCTN3 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
CCT2 CCT5 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
CCT3 CCT7 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
LIMS1 NCK2 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
NACA BTF3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 24981860 26344197 21203952 30948508 33644029 10982809
LIMS2 ILK â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 23455922 12167643 32707033 16189514 19293945
ILK LIMS2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
HSP90AB1 SUGT1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CTNNB1 GSK3B â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
COPB2 COPG1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7744004 12879077 23455922 15548653 10802735 24276241 31871319 10684602 21167153 19596003 12606577 10360579 18057010 20936779 11157984 25150978 18426980 21029865 12650940 9705280 8107774 23175184 21048135 31478661 9535855 16678097
LIMS1 RSU1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
RICTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 24036451
MTOR RICTOR â—¼   COLOCALIZATION ✅ 0.97 0.97 mint 21045808 8088164
FN1 ITGB3 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
PARVA PXN â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ACACA BRCA1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
HSP90AA1 PTGES3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
BTF3 NACA â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
LIMS1 ILK â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 23455922 18339839 26496610 11078733 23414517 31578224 26172215 26344197 32707033 23877428 19293945 32296183 17353931 25852190 19117955 22767580 28514442 25416956 16189514 10022929 19074270 11331308 26186194 12167643
PARVB ILK â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 23455922 26344197 17353931 15467740 26496610 28514442 32707033 11402068
PARVA ILK â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 23455922 25502805 11694518 17553790 26496610 21516116 22863883 26344197 22441983 15284246 32707033 23877428 12432066 32296183 17353931 25852190 22767580 28514442 25416956 16189514 11331308 26186194
RSU1 LIMS1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 28514442 33961781 26344197 29892012 26186194 25416956 23414517 15878342
HSP90AA1 SUGT1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ILK PARVA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NUP205 NUP93 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ILK LIMS1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CTNNA1 CTNNB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RUVBL1 RUVBL2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GRB2 SOS1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
JUN MAPK8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ILK GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15207235 14990992 16799642 20827300 27683053 9736715 12960424 26547035 17490631 12629168 17182785 21035499 16189514 17107957 16936772 17485554
PRKACA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16543730 15845746 18691976 19836308 8524413 12054501 16039586 12147701 16522636 11035810 18669648
MAPK1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16039586 28646232 18451303
GSK3B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16568235 12162494
GSK3B JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 23331499 1846781 25979842 25241761 20537194 21278055 21397588 17482134 1516134 8384355 17570479 16023596 17215518 30086763 92065884 24632621
GSK3B NACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15005626
GSK3B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 183.0 1.0 Omnipath 22415718 11967263 27158593 29455668 19303846 19797085 8638126 19293931 23056571 22662165 25352148 16611981 27068260 28337019 10671551 21743491 20688898 16293724 23721711 23552738 18687691 28977889 19622173 12051714 25241761 27683053 28549350 22699938 19565571 23076981 21562161 19575820 20219694 20537194 10330181 21986938 29183346 27773936 11251183 19711366 21035499 19675674 7542250 23151663 24451375 14663202 23804296 8524413 25639486 23770025 18070361 26892600 30143633 9233789 19667122 27507058 19061640 19223551 29387014 23331499 16199882 11533658 18644116 24501426 24913829 11835406 17318191 26014148 25366337 28183999 22640743 26910375 12000790 12114015 18387957 19107203 9832503 16371461 29805709 27462866 20137080 27902311 12040186 19576224 25644994 12615961 19060929 25897075 12851486 15465828 17053159 18952601 10228155 15020233 17444818 20140245 26453498 17052453 16944320 24015932 23602568 24975844 24931005 28948000 20080742 23209942 30271168 28220106 16520547 28430641 11818547 25546293 27672271 11955436 11154277 26373837 16039586 23778311 28697793 20302655 25136145 26905812 22216350 8666229 12957350 23109003 10074433 28529629 20215423 21329734 11254732 9501208 27098453 27281614 30279527 19631635 25482131 18455992 24403311 11274345
GSK3B CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16944320 11348595 11967263 14663202 8524413 20080742 19797085 12040186 16611981 10671551 16039586 12615961 15465828 17928543 24063632 10671552 15020233 19575820 17444818 20537194 17052453 9832503 18455992 16371461 11274345
CDC42 PXN â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10934474 11248548 11340065 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18719708 19741094 21178402 22126964 22821962 27248291 7761442 9831565
MAPK1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10753946 15494312 11784715 14636584
MAPK8 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20068231 18713649 12853963 23890137
PAK1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 26598620 10330411 11096073 16717130 14580336 18986306 27542844 28214467 25472536 17440071 23317503
PXN ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11694518 11304546 10592173 16936772 17553790
MAPK1 MBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 11258664 17255944 12760422 10371216 12944901 1939237 9792705 16401070 15380617
BRCA1 ACACA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11877377 15459660 16326698 19793801 20029420 21060331 21337561 25979092
BRCA1 ACACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 16698035 19061860 12360400 24565757 18452305 16713569 16326698
PRKACA ACACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7907095 2900138
ADAM12 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10944520 15242759
ARHGEF6 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23455922 11157752 9659915 10592173 15688026 21900206
MAPK1 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
SMO ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15618519 23074268
PLN ATP2A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11854448 10809745 11526231 16189514 12838339
BRCA1 AURKA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
BRCA1 AURKA â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
PRKACA AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23861900 16222244 16246726 33744274 29764989 26165940 11039908 17545617 27242098 26481147 28869606 26134678 33988677 26831064 33760847 16083426 17895985
PAK1 AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24867643 16246726 22864622 21589936
AURKA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22864622 22340593 18026198 24775809 14990569
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 FANCI â—¼   PHYSICAL_INTERACTION 55.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 FANCI â—¼   SHARES_COMPLEX 55.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 CHEK1 â—¼   REGULATES ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
CREB1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9528858 19882681 18160048 23447579 11704836
PPP1CA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 25056273 12438214 17511879 17603999
MAPK1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24342355 17290218
PPP5C CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21360678 18922470
IQGAP1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 17145710 9182573 8798539 12377780 9199170 8670801 17563371 8702968 12745076 15695813 21876773 8756646 12900413 18809683
CDC42 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25241761 12213839 25284480 18426980 10930450
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
TWIST1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 23331011 23232513 21876555 23424071 22899291 20714342 20818389 19272800 15311212 20053763 19581928 17487558 20182623 21796367 24157255 18062917
TWIST1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15169839 17615296 22796940 20818389 21685935 20519943 12508111 11309385 15640618 19597490 18062917 14673164
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
CDH1 CTNNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 7542250 19016843 25468996 9326449 16212417 11960376 11801604 8227214 10381631 16219695 9700170 24336504 22750944 9233779 11226248
ITGB1 CFL1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 15866889 16919435 17522712 18037882 19161977 19339212 19454690 19487819 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
PRKACA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 28003367 23060444 25867080 21455600 30600261 1716180 28242698 19328185 32102849 92316961 19095655 14602047 7530719 10581361 11053017 9385646 25330774 15657296 1377674
HSPA8 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21148293 10666020 19878303 21697503
CHEK1 FANCI â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801
CREB1 PRKACA â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 19244110 12150772 12082174 2573431 9733829 17908236 15879576
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
CREB1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 2170405 22357921 8648265 15908479 1845987 8803927 2542772 15608673 1404598 1320003 12372774
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
PRKACA CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11175347 12356771 15733869 11160957 21902831 2885756 2875459 7958915 9829964 12235136 12763014 9687510 8887554 15568017 11698596 8688081 9528766 11018520 11969286 11909979 8336722
CTNNA1 IQGAP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
CTNNB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20300972 19671687 16007074 9990071
RXRA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12771132 25241761
JUN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17146436 18347071 16007074
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
PAK1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 28007610 28423670 23543898 25639486 26547035 22369945 23162742 25472536 21822311 25225063 27713506 27910850
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
HSPA8 DNAJA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20084477 20809635 24012426 7828728 20072699
JUN EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740983 1918021 22301113 21239258 12208352 21216243
FKBP8 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24205284 17991864
ITGB1 FN1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
JUN FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24342046 21479385 11052809 9756884 23744703 10325245 11896591 10421838
FN1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11423542 1694173 18480047 1532572 8663002 17015452
FN1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9842903 22451694 17015452 18480047 19738201 7688313 1694173 6325925 25237190 26456826 10772816 7626807 21985969 6284125 1532572 11010812 8120056
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
PRKACA FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9920881 20068231 18452278 8248197 1545828
MAPK1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 12134156 20506250 15547943 8248197 7816602 15084594 12697810 8226933 20068231 18452278 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 21098038 9604935 11274345
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
RIPK3 GLUD1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
RIPK3 GLUD1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
RIPK3 GLUD1 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
SOS1 GRB2 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 8810325 33961781 8695800 7510700 8626525 34407391 16520382 10570290 16906159 16893902 7642581 8816480 9447984 12577067 11964172 8112292 8493579 7664271 16713569 7516467 19380743 9009162 10207103 17474147 10477741 32062451 7629138 21706016 20473329 19323566 9872323 32203420 7514169 21988832 28166272 28514442 9716598 11997436 9344843 15192046 10716926 8479541 14679214 8943292 31980649 7629168 7559490 9478994 7527391 8188688 11960376 10025673 11726515 7773779 10319320 9569023 9797459
JUN GRB2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
GRB2 ITGB1 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
GRB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 145.0 1.0 Omnipath 9544989 9872323 7642581 15746962 11726515 8621483 23334917 16520382 11997436 21706016 10359574 8950973 7664271 16713569 16893902 16906159 21988832 19323566 9009162 10716926 11964172 7629168 9815779 10592173 9716598 8647802 28166272 7773778 7773779 18778683 8188688 10319320 8810325 9344843 23452850 11960376 8816480 10025673 7510700 8940013 12955078 9697839 12345678 10477741 8493579 8943292 12577067 7862167 9199344 8112292 7898932 10207103 8695800 19531499 10570290 7760801 20005866 19380743 9447984 8235613 8479540 7527391 14679214 8479541 17474147 7514169 7629138
GRB2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12522133
PTGES3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16565516 10642522 11447118 26804907 15916966 11413142 16403413 21988832 11812147 19875381 19740745 14761955 12077419 10811660 20039095 22806877 25036637 20048054 19996313 18285346 20661446 22315411 23022381 18172314 20159553 22729780 22504172 16289154 9817749 14987994 8114727
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
ITGB1 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18339839 9736715 8538749 16189514 11402068
PAK1 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22521536 25738875 27642646 17420447
ILK NACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15299025
ILK PPP1R14B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12144526 12030846 16397254
ILK PPP1R14C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12804574 11812771
ILK PPP1R14A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12144526 15003508 12030846 11287002 16472257 15665049 12563012 15184667 12604330 15212693
ILK PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 15826939 11931630 11384979 12030846 18669648 18767875 12220642 18077418 12563012 25168281 12919947 10601309 24356468 12600888 18212344
IQGAP1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15655247 11319218 8226933 1330321 1497021909368021 16135787 17563371 7992057 8248196
VTN ITGB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 2412224 2420006 7685013 7542669
SPP1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10593924 7592829
VTN ITGB3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 7525578 7559467 17968485 9251239 7685013 9443892
VTN ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16195248 11331280
PDPK1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18578522 10896934
ITGB4 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9428518 11733063 12867433 7721947 8143784
JUN S100A9 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11001584 11274345 16054035 16396903 16406505 16880536 17000779 17439715 17638910 18754008 18813803 19081070 19190345 19219074 20107231 22354771 23031257 26587781 8545107
JUN SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15557322 15790955 20339243 21467818 19880446 14990565 16491116 17360982
JUN PPARD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15470497 18625220
MAPK8 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 202.0 1.0 Omnipath 17143273 17804415 10617656 8846788 15958389 11948398 10882101 20028971 12697749 15894542 20514406 14612408 17875713 9891069 17570479 18922473 11809792 8586671 11896587 12185592 12871843 7992057 7600582 11278395 8137421 8001819 10493750 14557262 16549498 18707149 9169478 11460167 15289320 8157646 16007099 20506250 22110360 15378002 9687508 12740383 20732415 9305638 19270716 23331499 10747973 16291755 16393692 12832416 18988627 10713700 18669648 12087092 14633987 8525045 15677475 16076903 16166642 18650425 15590691 1608942 19910486 18212344 11562357 12228228 16740711 14701799 19690332 10871633 12531896 16713569 8654373 16983342 19664995 15302935 10962563 15068801 8621542 8607977 18362184 10393177 20068231 9808624 14572659 8224842 10585392 9407028 17363973 19527717 19436832 14517282 12407442 9487126 9692890 14523011 15212693 10908726 11108663 13130464 10064600 18429822 15299005 9774977 11907583 12963725 16824735 19413330 10617104 17055484 21071413 18452278 16434970 16157600 7737130 23816567 10987838 17189706 9561845 9575168 1460037 7652575 18617513 24113186 11971971 11801649 25098452 20058876 16533805 9184210 18003900 9315636 10385525 18957422 12881422 11274345 12052834 15749833
MAPK1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8072547 11313929 15378002 12531896 12853483 23720779 9662434 1496019 17570479 1922387 11278277 11739718 16023596 20086174 25557171 7737130 26755651 8224842 14676207 17920329 25201974 9022811 22327296 18650425 8137421 18443042 12881422 18572021 17001009 33767435 7744008 23616010 26745678 14617628 11432833 16819515 22606284 12040039
PRKACA LASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12571245 15465019 12432067 22665060 26061439 25225353
MAPK1 TWIST1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21502402 26959880 26975371 18775330 31540485 8226933 9604935 8388392
MAPK1 PARVA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15353548 22955285
MAPK1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10197981 8816480 9922370 8626428
MAPK1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10377179 17604322 12048211
MAPK1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23597856 26637332 16627622
MAPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19604315 15542607 16964243 15212693 11604394
RHOA MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15659383 25241761 8824197
MAPK8 TWIST1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21502402
MAPK8 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16551633 10383391 10938283 16038797
MTOR RICTOR â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RICTOR â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MYL12B PPP1R12A â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PAK1 NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 10026169 25416956 10592173 31515488 11557983 32296183 16713569
NCK2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 10026169 25416956 10592173 31515488 11557983 32296183 16713569
NDUFA4 NDUFS3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFS3 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
SOS1 PAK1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
PDPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11134074 21726627 21209852 10995762 23885116 26009991 26238471 10551809 25335797
PDPK1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 16026785 20732331 15481030 22493239 10698939 9707564 8706898 20137943 21774789 17192257 22154087 20481595 12372837 16765046
PRKACA PLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 2544595 12134142 3759968 10988285 12692124 9468536 33897445
RXRA PPARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 22205725 23331499 15604093 9933587 19756148 11237216 15888456
RXRB PPARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22205725 23331499 15604093 11237216
PPP1CA TRIM28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20424263
PPP1R12A RHOA â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
SMO PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20016067 23331499 20643644 20956384 21209912 18820483 17641202 17688959 18997815 19549984 19592253 14611647
PRKACA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12654918 21572420 20591975 8599934 16109481 34088899 11162591 15890975
PRKACA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11162439
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368