Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
IFIT5 CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
IFIT3 CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
LONP1 CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CDC37 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CDC37 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPD1 CEP164 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90AA1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
DNAJA1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
CNTRL HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
C1QBP MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
COX5B COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
COX5B COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
LONP1 COX5B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
COX7C COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
COX7C COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
LONP1 COX7C â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
LONP1 ECSIT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
RNF32 ECSIT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
LOXL4 ECSIT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
ECSIT APOE â—¼   COLOCALIZATION 2.0 0.8 intact 21163940 114280
LONP1 COX4I1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
COX5A COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
COX5A COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
LONP1 COX5A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
COX6C COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
COX6C COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
LONP1 COX6C â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
MT-CO1 COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
MT-CO1 COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
LONP1 MT-CO1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
MT-CO2 COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
MT-CO2 COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
LONP1 MT-CO2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
MT-CO3 COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
MT-CO3 COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
LONP1 MT-CO3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
HIF1A FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16601206 15192019
HIF1A NKX2-5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21055290 18303027
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
LOXL4 LONP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
RNF32 LONP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
LONP1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
LONP1 CYP2C8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
LONP1 COX4I2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
LONP1 ACO2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12198491 17418790
STAT5A LONP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15528381
STAT5A PDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22698918 17360981
RNF32 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CYP2C8 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
LOXL4 APOE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
HSPA8 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STAT5A JAK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8709637 7489741
MAST1 CYP2C8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
GATA3 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19674970 11397697
IFIT5 IFIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
IFIT3 A2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
IFIT5 A2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
CYP2C8 A2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
STAT5A A2M â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8825557 7519723
ILK PXN â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
MT-CO2 NDUFA4 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
RHOB EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
EGFR IGF1R â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
MYC DCTN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
COX6C COX7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 33961781
LONP1 NDUFS7 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
COX6C COX5A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 23260140
BMI1 NCBP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
RHOB MINK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RAC2 RAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 RAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
IFIT3 IFIT5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21163940 21642987
COX5B COX6C â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CDC37 RAF1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
FLT1 FLT4 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
RHOJ CDC42 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31871319 10967094
JAK3 STAT5A â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 18250158
MYC HIF1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 15071503 28205554
COX5B NDUFA4 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
COX6C COX7C â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
EGFR MAST1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20029029 31980649
COX4I1 NDUFA4 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
COX5A NDUFA4 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
COX7C NDUFA4 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
COX4I1 MT-CO3 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
COX6C NDUFA4 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
AKT1 CDC37 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
EGFR RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
ILK RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23455922 26496610 25852190
EGFR HSPA8 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
RAF1 CDC37 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25036637 31980649 24189400 24292678 17979178 33961781 32707033 16611982 16335536
CDC37 AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22504172 12176997 31980649 24869908
CDC37 AURKB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25036637 33961781 26186194 31586073 32707033 29568061
ILK AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 12149249 9736715 12176337 11445557 18339839 11825911 11313365 14500673 11278835 11546794
AKT1 PDK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27166089 27505672 34278744
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
EGFR STAT5A â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
COX4I1 COX7C â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
AURKAIP1 MRPS24 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
DNAJA1 HSPA8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
EGFR MET â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
EGFR CDC37 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25036637 31980649 12471035 24189400 23956138
EGFR AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
CDC37 DCTN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EGFR MET â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20624308 24189400 21918175 24362532 10722725 23866081 26551075
GATA3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
GATA3 HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
MYC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 9315742 28628118 28205554
STAT5A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17927978 12048235 12967477
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
MYC MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15345217 9489489 23550155
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC ACO2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
AKT1 SMARCB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16568092
AKT1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 28628118 10576742 19197339 19058874 28205554
PAK6 CDC42 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 31980649 11773441 20936779 32707033
CDC42 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9574518 9305638 23109003
AKT1 DCTN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AKT1 LONP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31406245
PDK1 PRKCG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18669648 17053865
FLT3 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17356133 12796379
GATA1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
A2M TSC22D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
JAK3 STAT5A â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
CDC42 PAK6 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HSP90AA1 RAF1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
COX5B MT-CO3 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
COX5B COX7C â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
COX4I1 MT-CO1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
COX5B MT-CO1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
COX5A NDUFS7 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
MT-CO1 MT-CO2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COX4I1 COX6C â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
COX4I1 COX5A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COX5B MT-CO2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
COX7C MT-CO2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
COX6C MT-CO2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
HSPA8 DNAJA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20084477 20809635 24012426 7828728 20072699
PRKCG EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
EGFR STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 31980649 10358079 24658140 25402006 18586824 16729043
PRKCG HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 26804907 24117238
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
HSP90AA1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 25036637 19011619 16093354 8962087 18266962 8408024 23118896 22939624 24462205 16189514 17699868 20039095 16504566 20159553 17409432 16330544 15618521
MYC HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19022255 12695333 14519204 21995449 11983916 11085504
MYC PDK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 11283613 11283614 11704864 16517405 16517406 17055429 17558397 17785433 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
GATA1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24336126 19522008 12832487
GATA2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19522008 22951020
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
MT-CO3 COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO1 COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX4I1 COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO3 COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX4I1 COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO1 COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C COX5B â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX4I1 COX5B â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C COX5B â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX7C â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX7C â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C MT-CO1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C COX4I1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C MT-CO3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C COX6C â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX7C â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX7C â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C MT-CO1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C MT-CO3 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C COX4I1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C COX6C â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX7C â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX7C â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C MT-CO3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C MT-CO1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
CDC42 PXN â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10934474 11248548 11340065 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18719708 19741094 21178402 22126964 22821962 27248291 7761442 9831565
PXN ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11694518 11304546 10592173 16936772 17553790
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
PAK6 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19165420 23162742 18465753 25632266
PRKCG RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8288587 17053865
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
NDUFA4 NDUFS7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA4 NDUFS7 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
ECSIT NDUFA4 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
ECSIT NDUFS7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
COX6C COX4I1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO3 COX4I1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO1 COX4I1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX4I1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX4I1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX4I1 MT-CO2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
MT-CO2 COX4I1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO1 COX4I1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C COX4I1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO3 COX4I1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX4I1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX4I1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO3 COX4I1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX4I1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO1 COX4I1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A MT-CO2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX6C â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A MT-CO3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A MT-CO1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A MT-CO1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A MT-CO3 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A MT-CO2 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX6C â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX6C â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX6C â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C MT-CO1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C MT-CO3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX6C â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C MT-CO3 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C MT-CO1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX6C â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C MT-CO3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX6C MT-CO1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 MT-CO1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO1 MT-CO3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 MT-CO1 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO1 MT-CO3 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 MT-CO3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 MT-CO3 â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
HIF1A PDK1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A LONP1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A COX4I2 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A PDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18269201 16517405 17855495
HIF1A MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16099863 17028975
HIF1A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19144925 17220299 17488804 14726529 15277220
HIF1A FLT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7539918 1823643 12829734 9159130 13130303 9746763 12080085 11566883 10403805 8943284 15451019 11528470 9278421 16887934 9295307
PAK6 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20936779 11773441 16189514
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
STAT5A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24218138 24469394 18042802 20385773
PDK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12176337 15743829 12682057 11445557 15899889 12149249 10833263 15718470 11278835 10226025 11087733 14500673 16341064 19897009 9368760 24012393 11825911 9512493 9736715 11313365 9868760 15364915
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27053161 16107690 20101202 8206977 26680303
AKT1 GATA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 27053161 15837948
MAP3K3 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18855897 11274345 21614932
JAK3 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 18250158 9382798 10037026 19088846 9047382 7777534 16189514 19414780
GATA1 GATA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19114560 12432220 20670937 14695898 21853041
PRKCG MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
RHOD PAK6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11784792 28486133 22665057 31871319 17916560