Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PAK5 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11756552 16189514
B2M RAB9A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ADAM9 PACSIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10531379 5211924
CANX MRPL16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAC1 CYFIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9417078 16189514
ETF1 RPS12 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
GNA11 GNB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
GNA11 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
RAB2A GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ITGA1 ILK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19397781 26148229
PRKACA IMMT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 27153535
PRKACA ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRIP10 LYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215944 12456510
PTPRJ MET â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6671721 12475979
NEDD4L SLC11A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0904880106 19706893
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
RHOA PIP5K1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 14681219
PTPRS RAB35 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAC1 RAB35 â—¼   COLOCALIZATION 2.0 0.8 intact 19289122 7012064
CHCHD3 IMMT â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
UTP18 UTP20 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
VAMP7 STX6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 19557002
DDX18 RBM28 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
LMAN1 PHB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
RAC1 PHB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
RAB1A RAB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
RAB2A RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
RAC1 SFXN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
RHOA THEM6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
CXCR4 ITCH â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
STX6 STX10 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26186194 34079125
PTPRK ADAM9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
GNAI2 MCU â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VTI1B STX10 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD44 MET â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28205554 28628118 22897854
OSMR JAK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10586060 28514442 33961781
STX10 VTI1B â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
RAB11B RAB8A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
GNAI2 GNB4 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
DDX18 DDX27 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
AAAS NDC1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
EHD2 AP2M1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15182197 16713569
FLOT1 RAB5C â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
ILK MMS19 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23455922 17353931
LYN MET â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24728074 34079125
PHB SFXN1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31536960 27025967 34079125
GOLGA2 RAB1A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
IL6ST JAK1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
VTI1B STX6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27791468 26186194 28514442 34079125
RAB5C RAB1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
HSD17B10 KIAA0391 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COBL PACSIN3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
RAB11B RAB1A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ILK DPM1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25852190 23455922 17353931
PTPRJ MET â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12475979 12370829 19167335
RAB2A PHB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26496610 26344197 34079125
RAB1A RAB8A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
PRKACA CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16785995
DVL3 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 12533515
PRKACA LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21262972 18981475 21406690
RAP1B PDHB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HLA-B B2M â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8624811 5220994
STX6 VTI1B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CANX GANAB â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
KRIT1 RAP1B â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RHOJ PAK1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 31871319 32814053 10967094 28514442 14521508
PVRL3 PARD3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 16189514 12515806
ABCE1 RPS12 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
ABCE1 ETF1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
MRPL16 MRPS5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
B2M HLA-B â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ITGAV ITGB5 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGAV ITGB5 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
JAK1 ITGB5 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
ITGB5 ITGA1 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
ADAM9 ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11162558
ADAM9 ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15361064 11162558
ATP5C1 ATP5L â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 10838049 11410595 11744738 12110673 14701807 14757859 18953340 22841746
ATP5C1 ATP5L â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 10838049 11410595 11744738 12110673 14701807 14757859 18953340 22841746
ATP5C1 ATP5L â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10838049 11410595 11744738 12110673 14701807 14757859 18953340 22841746
PRKACA AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23861900 16222244 16246726 33744274 29764989 26165940 11039908 17545617 27242098 26481147 28869606 26134678 33988677 26831064 33760847 16083426 17895985
PAK1 AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24867643 16246726 22864622 21589936
AURKA PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19812038
BMPR2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18756288 7791754 10712517
CD44 SLC9A1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16104017 9712871 15090545 8901634 11350981 17050540 15035633
CXCR4 RHOA â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
ITCH CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28264927 19116316 24489825
CXCR4 GNAI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
LRP6 DVL3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
GNAI2 LYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 11160627 10753828 9722546
RAB1A GOLGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11285137 11718716 11739401 16189514 12788069
JAK1 IFNGR1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNGR1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12133952 8232552 8550631 8156998 7796299 7615558 8649432 19041276
JAK1 IL4R â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 1825141 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 2965306 7512720 7521688 7543512 9535722 9834059
JAK1 IL4R â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 1825141 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 2965306 7512720 7521688 7543512 9535722 9834059
JAK1 IL4R â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 1825141 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 2965306 7512720 7521688 7543512 9535722 9834059
IL4R JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11127821 23331499 12704343 12133952 17312100 23124025 7929391 12223527
JAK1 IL6ST â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8390097 9238703 16051226 11943154
OSMR IL6ST â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10692570 23331499 21071413 10854424 18988627 8999038 9188471
IL6ST JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7896787 23331499 11468294 9388212 21220115 24710148 11742534 23663276 12487370
PAK1 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22521536 25738875 27642646 17420447
LYN JAK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8197119 16492764 16720384 7512720 10537111
OSMR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10586060 23331499 15935618
PRKACA KCNJ12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11181181
PRKACA KCNJ12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11181181
MAP4K4 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22216214 11369779 20936779
PTPRJ MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12370829 15475459 19167335 12475979
RAC1 MTOR â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
RAC1 MTOR â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
RAC1 MTOR â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
RAC1 MTOR â—¼   DOWN_REGULATES ✅ - 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
PRKACA NEDD4L â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 30453017 15328345 15677482
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
RAC1 PIP5K1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16212495 12874273 12480336 11152757 10679324 14681219
PRKACA RAP1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8463283 19651783 27760305 12089143 1551424 90343822
PRKACA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12654918 21572420 20591975 8599934 16109481 34088899 11162591 15890975
STX10 RAB9A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 18195106 25343031 16885419 19620288 18946081 17488291 8440258