SFN
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11574543
5214598
|
SMAD3
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11906909
16603637
|
YWHAQ
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12426317
16713569
|
CSF1R
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
FYN
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
5220480
7642581
|
ITCH
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12226085
5215735
|
SFN
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11697890
8005785
|
FYN
|
CBL
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.8
|
0.8
|
mint
|
5217342
15556646
|
CBL
|
FYN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.8
|
0.8
|
mint
|
5217342
15556646
|
CBL
|
MET
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5215187
11894096
|
CBL
|
FGFR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBL
|
SH3GL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11894095
16713569
|
CBL
|
ERBB4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBL
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBL
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBL
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
UBE2K
|
DTX3L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HGS
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20308550
0911188107
|
NUMB
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
UBE2D1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
JUNB
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12791272
|
TP53
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
GSN
|
NFE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
STAM2
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
GGA3
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15611048
5217420
|
HGS
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
HGS
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
ARRDC3
|
HGS
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
MET
|
HGS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
8380735
|
TP53
|
SFN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7711923
20206173
|
SMARCC1
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
NCOA1
|
SMARCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15923603
|
SMARCC2
|
POLR2C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SMARCC2
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SMARCC2
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
UBB
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SLC1A5
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TP53
|
SMAD3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21900401
|
TP53
|
COL18A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15958553
|
IKBKB
|
TP53
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19196987
0812256106
|
RCHY1
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5220017
17568776
|
TP53
|
TNFRSF10B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11498783
|
TP53
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7915517
|
TP53
|
COL18A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
BECN1
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0810452105
19050071
|
YAP1
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5213829
11278685
|
TP73
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19815500
0905867106
|
TP63
|
WWP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18806757
20951678
|
TP63
|
NOTCH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20442293
20950370
|
IKBKB
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23589370
33548094
|
TP73
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15678106
5217499
|
WWOX
|
TP73
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5216996
15070730
|
TP73
|
WWOX
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5216996
15070730
|
YWHAQ
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12535517
5216053
|
ARRDC3
|
ADRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
ADRB2
|
ARRDC3
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
UBE2D1
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
UBE2D1
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22842904
21857666
|
WWP1
|
ATN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
EWSR1
|
ATN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
RCHY1
|
ATN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
ATN1
|
EWSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
UBE2D4
|
RNF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
BECN1
|
RNF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TAX1BP1
|
RNF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
RNF11
|
GGA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
RNF11
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
RNF11
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8012720
20676133
|
RNF11
|
UBE2E3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RNF11
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19131965
23010170
|
RNF11
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19131965
|
CALM3
|
TRPV4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12724311
21837266
|
CALM3
|
PPP3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15757646
293720
|
CALM2
|
TRPV4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12724311
21837266
|
BECN1
|
USP13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21962518
22216260
|
TNFAIP3
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20501938
|
SH3GLB1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21311563
17891140
|
UBB
|
STAM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
UBB
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
UBB
|
USP5
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
26235645
7851534
|
USP5
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26235645
16007098
|
KDR
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219079
16966330
|
FYN
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7524477
6730342
|
ERBB3
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16729043
5218694
|
CSK
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16678999
6731761
|
WASL
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11340081
16525419
|
HDAC6
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
FYN
|
CSF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6730431
7681396
|
MAP3K7
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219785
17363973
|
CYLD
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
29291351
18332137
|
RIPK1
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
31138766
24316671
|
TNFAIP3
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19131965
20599425
|
TAX1BP1
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19131965
23010170
|
CYLD
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19131965
23010170
|
CYLD
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17981138
19131965
|
RIPK1
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21119000
18362886
|
SMAD7
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10519551
19758997
|
TGFB1
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21358634
9679059
|
KPNB1
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
TGFBR1
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18511908
6798777
|
TGFBR1
|
SMAD2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
10973958
|
PRKACA
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SMAD3
|
SMN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20123992
21965288
|
SMAD3
|
MET
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15339794
|
ARRB2
|
DTX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22162134
16284625
|
NOTCH1
|
DTX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14567914
15965470
|
ITCH
|
DTX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17028573
5219205
|
ITCH
|
DTX1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17028573
5219205
|
ARRB2
|
NOTCH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22162134
16284625
|
NOTCH1
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8313469
19567869
|
NOTCH1
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22162134
16284625
|
NOTCH1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17537801
|
WWP1
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15221015
|
CBLC
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
PPP3CB
|
PPP3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
10195903
7593193
|
PPP3CB
|
PPP3R1
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
10195903
7593193
|
MLKL
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
31138766
24316671
|
PDCD6IP
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
31138766
24316671
|
MAPK8
|
CFLAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18471544
|
LRRK2
|
POU5F1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
LRRK2
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19302196
|
LRRK2
|
SH3GL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22998870
|
CAV1
|
LRP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16890161
|
CBLC
|
FLT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
UBE2K
|
CBLC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ITCH
|
CBLC
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
12226085
5215735
|
CBLC
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLC
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLC
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLC
|
ERBB4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLC
|
FGFR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLC
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLC
|
FGFR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLC
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
FGFR3
|
JUNB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FGFR3
|
NFE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FGFR3
|
STAM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FGFR3
|
HNRNPL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
N4BP1
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0701773104
17592138
|
ITCH
|
SGK3
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5218909
16888620
|
ITCH
|
SH3GL2
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5216835
14684745
|
PI4K2A
|
ITCH
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23146885
8426259
|
SGK3
|
ITCH
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5218909
16888620
|
SH3GL2
|
ITCH
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5216835
14684745
|
MAVS
|
CYLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18636086
6804508
|
TNFAIP3
|
LAPTM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
EWSR1
|
ATXN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PRKACA
|
ATXN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
USP13
|
ATXN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
WWP1
|
ATXN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ATXN3
|
EWSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
NCOA1
|
SCNN1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17105732
20054001
|
SF1
|
HNRNPUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
HNRNPUL1
|
SMN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
ADRB2
|
ARRB2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
ARRB1
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16407241
11171997
|
ITSN1
|
WASL
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5214632
11584276
|
NRG1
|
ERBB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10768865
23365119
|
WWP1
|
CPSF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CPSF6
|
EWSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CPSF6
|
WWP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
WWOX
|
CPSF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217863
16055720
|
CPSF7
|
EWSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
UBE2O
|
SMAD6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8429180
23455153
|
UBE2O
|
SMAD6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23455153
|
POLR2C
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0804424105
18562274
|
POLR2C
|
POLR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0804424105
18562274
|
TRIM25
|
IFIH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18353649
|
ADRB2
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
SMN1
|
NDFIP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
WWP1
|
EWSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
WWP1
|
LAPTM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SNX9
|
SNX18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23085988
8408210
|
SH3GLB1
|
SPART
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SH3GLB1
|
UBE2G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ANKRD13A
|
LAPTM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
LAPTM5
|
USP13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
UBB
|
USP12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
YWHAQ
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
8005785
11697890
|
KIT
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
8950973
16780420
25737303
15315962
|
WWOX
|
ERBB4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
19047365
16061658
24550385
20943952
22584572
|
TRIM25
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
810.0
|
0.81
|
STRING
|
36370105
|
NTRK1
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25921289
21570973
|
NUMB
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16273093
25754235
|
EGFR
|
IGF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17047074
17307140
|
ARRB1
|
HGS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23208550
20505072
|
HGS
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23208550
20505072
|
LRRK2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
LITAF
|
UBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TAB1
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
5218828
16845370
|
LRRK1
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19712061
20144646
|
ARRB2
|
TAB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25241761
17620599
|
CFTR
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26618866
31324722
|
LITAF
|
FGFR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ARRB1
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17947233
18544533
|
SARAF
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TRPV4
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17110928
20650893
|
CFTR
|
USP9X
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31324722
17110338
|
MAVS
|
CYLD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
18636086
30410068
|
MAVS
|
PCBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25135833
19881509
|
MET
|
ERBB3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25326665
21918175
|
USP9X
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
UBB
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
TNFAIP3
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
825.0
|
0.82
|
STRING
|
36370105
|
CBL
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12226085
19341794
|
USP9X
|
YAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22939629
26598551
29449692
|
UBB
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
RNF11
|
GGA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25195858
15231748
|
CSK
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10753943
19262695
|
RIPK1
|
CYLD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
17981138
21408173
33654169
22848449
28900035
|
SMAD7
|
TAB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12589052
11737269
|
SMAD3
|
WWP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
25416956
25910212
15221015
15359284
|
ARRB1
|
IGF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33158816
15878855
21685939
|
WBP1
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ITCH
|
LITAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21326863
25963657
|
SOX2
|
USP9X
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
23667531
31605775
|
HDAC6
|
CFTR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31501480
22069321
14675537
|
UBE2K
|
DDX58
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32513696
17719635
|
WASL
|
RHOJ
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
25416956
31871319
|
SARAF
|
WWP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
32878247
|
UBA1
|
UBE2E2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
ERBB4
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
CALM3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
MAP3K7
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
NEDD9
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CBL
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
BCL10
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
HGS
|
UBA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
19019082
25260751
|
TRPV4
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12538589
16713569
|
CYLD
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
DDX58
|
RNF135
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
ITCH
|
TP73
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
GGA3
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
DDX20
|
GEMIN8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
STAM
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
STAM2
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
UBB
|
USP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
HDAC6
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
DTX1
|
NOTCH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
848.0
|
0.84
|
STRING
|
36370105
|
RNF11
|
STAM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16189514
16713569
24377927
32814053
23222715
15231748
|
GLI1
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
20818436
31278361
|
CBLC
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12226085
|
ITCH
|
WBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27578003
16055720
29497031
26508657
|
ERBB4
|
ERBB3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
7689552
10572067
20227043
25315821
|
WWOX
|
CPSF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32296183
16055720
24550385
|
TP53
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
TP53BP2
|
TP73
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
UBA1
|
UBE2D4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
MET
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
6538879
18273061
|
CBL
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11149930
19380743
|
MET
|
CBL
|
â—¼ UBIQUITINATION
|
✅
|
|
0.86
|
0.86
|
mint
|
11894096
5215187
|
RNF11
|
WWP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16189514
16713569
28292929
31985874
15231748
18724389
|
ERBB3
|
HDAC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20029029
31980649
|
ERBB4
|
HDAC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20029029
31980649
|
ATXN3
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
NRG1
|
ERBB3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
7514177
|
YAP1
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
CBLC
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
CUL3
|
UBE2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
CALM3
|
PPP3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
CALM1
|
PPP3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
CALM2
|
PPP3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
PDCD6IP
|
SH3GL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
EGFR
|
SNX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
WASL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
STAM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10993906
11687594
17403676
15212941
|
ITCH
|
ATN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9647693
16713569
|
UBB
|
RNF11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
14755250
|
CSK
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16713569
8262983
7524477
1985196
|
SMAD7
|
SMAD6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26555259
9256479
|
LRRK2
|
LRP6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
27013965
22899650
|
ITCH
|
CPSF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
16055720
26508657
|
PPP3R1
|
PPP3CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
7295928
19896943
|
HDAC6
|
CYLD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19893491
20593489
|
CPSF6
|
CPSF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
26496610
33961781
24981860
22939629
|
WWOX
|
LITAF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
32296183
15064722
|
EGFR
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
SH3GL1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CALM1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
ARRDC3
|
TNFAIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
TNFAIP3
|
TNIP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
CBL
|
UBE2L3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
MAP3K7
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ADRB2
|
ARRDC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
IFIH1
|
MAVS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
CPSF6
|
CPSF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
NUMB
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ITCH
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ERBB4
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
ARRDC3
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
CBL
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
SFN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
SMAD2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CFLAR
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
LRRK1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24947832
28065597
29513927
|
CAV1
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11805080
24632723
16678999
|
CSF1R
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7681396
16713569
|
CFLAR
|
RIPK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
17047155
21737330
11002417
10837247
26972597
|
MLKL
|
RIPK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
27560715
29883609
22265413
31358971
30420664
24316671
22265414
|
FGFR2
|
FGFR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
23972473
33961781
|
ARRB2
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
17947233
18544533
|
ITCH
|
NFE2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18718448
11318614
|
MAVS
|
IFIH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22623778
16127453
19881509
19416887
32612200
22301138
17600090
33372174
33649232
30193849
27312109
21903422
|
WBP2
|
WWP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28461335
27578003
9169421
33961781
31340145
|
SMN1
|
DDX20
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
11714716
5214807
|
WBP1
|
WWP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
16713569
9169421
33961781
26186194
|
CAV1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CBL
|
ITSN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
TP53
|
TP63
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
TP53BP2
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
AMOT
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
MAPK8
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
ARRDC3
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
NUDT21
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
UBA1
|
UBE2R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
PCNA
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
RCHY1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
ERBB4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25140053
23153581
25315821
16061658
10572067
|
EGFR
|
RET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
28460442
|
EGFR
|
TAB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
24658140
25402006
18271526
|
EGFR
|
HGS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23477725
12953068
20308550
23153581
23602387
25588945
18508924
15212941
|
EGFR
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
TP53
|
RCHY1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
17568776
5220017
|
TP53
|
RCHY1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.89
|
0.89
|
mint
|
17568776
5220017
|
AMOT
|
YAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
30266805
23564455
24976009
24225952
25751139
31501420
32292505
29891922
30472188
24106267
24255178
24101513
32755583
24366813
19615732
22385262
|
ITCH
|
RNF11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28292929
19131965
31985874
20676133
22507528
14559117
|
RIPK1
|
TNFAIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
SMAD3
|
JUNB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
10220381
10903323
|
CFLAR
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19808964
30736843
18559494
33631302
19090833
31443721
33469115
21474069
|
CAV1
|
LRP6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
34079125
28966723
16890161
|
ITCH
|
NUMB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20818436
12682059
18628966
|
ERBB4
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17463226
18334649
|
SPG20
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
20504295
16055720
33961781
19307600
19765186
19580544
|
TAX1BP1
|
TNFAIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
STK3
|
RASSF5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
24981860
|
MAVS
|
DDX58
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22114345
20007272
32612200
31433974
20071582
22022264
19164550
30193849
30267576
21903422
33649232
20554965
16153868
20080758
21102435
21292167
29053956
26494172
26061460
33372174
28594325
21844353
30558248
16127453
18200010
16177806
22301138
17190814
29263274
24478431
20434986
22623778
16585524
19193793
34544279
17709747
19454348
20406818
33976430
|
WWP1
|
CPSF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16189514
16713569
33961781
19447967
|
WWOX
|
WBP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
15064722
|
SPG20
|
WWP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
19307600
31340145
19765186
19580544
|
CDC34
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
ADRB2
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
TP73
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
IKBKB
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
20332299
|
EGFR
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
16829981
|
IKBKB
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
SMAD3
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
TNFAIP3
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
BAX
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
15574335
20956295
23374347
17289999
|
EGFR
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27059931
7657591
8665853
27903975
15107835
24797263
28791635
9756944
23799367
23175185
28198003
12734385
14505571
20940296
19155296
10635327
15117950
22833562
29629558
12061819
8662998
10086340
33762435
11994282
20877636
32714745
25005938
31182136
19578043
7782294
24714105
10799548
23158001
26055326
33617900
23153581
15210722
25872741
15657067
19947936
10428778
18508924
16969069
17971399
15962011
19531499
25521828
23774213
22976291
31959764
22591401
18255265
15735736
16713569
20562913
17880946
16914641
9890970
22394513
16729043
32114396
17995934
17182860
18319245
18271526
17545148
15383614
25140053
32377695
15465819
33627783
8798643
25754235
15282549
26177020
22266821
16923119
17242169
30544639
12604776
11239464
9130710
19225046
11370743
21772844
16105874
18273061
7592693
23897813
17486068
16246327
23457600
32904620
12803489
31120930
15668240
22203672
23418353
20124286
28541302
33323455
10092522
14627991
15677445
15159412
20308550
16849543
12593795
19836242
9121472
19713535
18316398
11408594
|
CBL
|
RET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32062451
12727845
15677445
28794017
|
CBL
|
ITSN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21712076
18654987
16914641
18539136
|
CBL
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11894096
25241761
18273061
19433454
21222362
19450681
21163258
16397241
17533376
15123609
|
CBL
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18632619
17635922
10514377
|
CBLC
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22888118
29945960
10571044
10362357
31959764
|
ERBB3
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21278786
24189400
27756321
18803307
17148612
25315821
22439932
10527633
23436906
23866081
10572067
|
EGFR
|
MET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20624308
24189400
21918175
24362532
10722725
23866081
26551075
|
EGFR
|
NRG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
7730382
25402006
31980649
24658140
|
EGFR
|
HDAC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20029029
31980649
24658140
20133936
25402006
|
EGFR
|
CSK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24797263
31980649
24658140
25402006
16729043
|
EGFR
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16407214
19446582
22411794
31980649
12388423
24658140
15273741
25402006
16799092
9374534
34079125
12354760
10781609
15657067
|
JUNB
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10803405
23455325
|
TRIM25
|
SFN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12075357
16189514
|
TP53BP2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
21513714
8152471
|
TP53
|
HNRNPUL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16980608
|
HNRNPUL1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15907477
|
TP73
|
TP63
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16413471
21436470
18026135
|
TP73
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11238924
19815500
10373484
|
TP63
|
YAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11278685
35044719
|
WWOX
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15070730
|
UBA1
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17597759
24816145
21209336
|
YAP1
|
ERBB4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19047365
12807903
15023535
16061658
25283809
|
YAP1
|
SMAD7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25283809
22921829
12118366
|
CALM1
|
TRPV4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12724311
21837266
|
POLR2C
|
NUDT21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CAV1
|
KDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20462514
12529448
19923922
|
CSK
|
CD274
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12947224
18173375
18759926
|
CSK
|
PDCD1LG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12947224
18173375
18759926
|
MAP3K7
|
BCL10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17158449
15327770
10882101
|
IKBKB
|
BCL10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
19909372
16301747
16356855
|
BCL10
|
TAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17158449
15327770
10882101
|
PRKACA
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20658524
|
FYN
|
TRPV4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12538589
16713569
|
MAP3K7
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9380693
|
RIPK3
|
RIPK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24098568
31358971
30420664
21903422
19524513
22864571
23744296
22817896
29883609
22265413
19524512
26786097
10339433
25882049
26319693
22265414
29352166
26559832
29497034
|
TNFRSF10B
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9430227
|
KLF10
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
22234868
12173049
12244575
|
SMAD2
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
SMAD2
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
27974707
11456453
16284942
|
ITCH
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15350225
23331499
|
SMAD6
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9892110
|
NOTCH1
|
DTX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10933396
9881968
15356142
|
ITCH
|
DTX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17028573
|
SPOP
|
CUL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22911784
21577200
21988832
19256485
28216678
29160310
25011449
30244836
16524876
22013077
22632832
33961781
25278611
19261606
31559706
|
PRKACA
|
LRRK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
21390248
24351927
|
PDCD6IP
|
TAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
PRKACA
|
LRP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21262972
18981475
21406690
|
MAPK8
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
ADRB2
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23208550
24658140
17148612
24561123
27226565
|
ARRB2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24069330
17353931
33961781
17620599
|
ITSN1
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
PCBP2
|
MAVS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
25135833
19881509
|
ERBB3
|
NRG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
31467278
30523157
10913256
9565587
7592681
8702572
28988771
11389077
17697999
33961781
11555649
9168115
|
ERBB4
|
NRG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10537356
9565587
28988771
8062828
7721889
9168115
|
ITSN1
|
UBE2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
UBA1
|
UBE2C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
SMAD2
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
BAX
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
SMARCC1
|
SMARCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
LRRK2
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
CBL
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
UBA1
|
UBE2E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
MLKL
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
CDC34
|
UBA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
UBA1
|
UBE2G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
WBP2
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
UBA1
|
UBE2L3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
JAG1
|
NOTCH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
RASSF5
|
STK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
ERBB3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
31862538
|
KPNB1
|
KPNA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
17596301
|
ERBB3
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
UBA1
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
DDX58
|
TRIM25
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
CBL
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
ARRDC3
|
UBE2E2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
ARRDC3
|
UBE2E3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
MAP2K4
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
GSN
|
WASL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
RNF11
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
UBE2L3
|
WWP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
UBB
|
YOD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
UBA1
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
RNF11
|
UBE2D4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
WBP1
|
YAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
25283809
9202023
7644498
11604498
|
ITCH
|
DTX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
17028573
18628966
|
ARID1A
|
SMARCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
UBA1
|
UBE2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
UBB
|
UBE2K
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
EGFR
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
16729043
5218694
|
CBL
|
CSF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
11850825
10025673
10648820
7782294
11847211
|
CBL
|
EGFR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16914641
7033849
028274
|
HGS
|
STAM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16189514
15113837
16713569
12551915
20504764
13679051
22939629
26344197
16429130
|
SMAD7
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
LRRK2
|
SFN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
DDX20
|
SMN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
CPSF7
|
NUDT21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
ITCH
|
UBE2L3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
FYN
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
17094785
8900205
15190072
9890970
25814554
8995358
12244174
10829062
12941616
9311917
12231245
16503409
9677430
8662998
119942
9535867
10092522
15208330
7642581
15556646
16713569
8621719
10629042
7782294
8626543
10799548
11239464
|
YAP1
|
WBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
27578003
7644498
27684187
25751139
25283809
26933062
30472188
24255178
24366813
|
WASL
|
ITSN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
18539136
11584276
|
HGS
|
STAM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
EGFR
|
ERBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
SFN
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
TRIM25
|
UBE2D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
TP53
|
TP53BP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
TNFAIP3
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
CPSF6
|
NUDT21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
FLT1
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
CBLC
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
DDX58
|
MAVS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
ARID1A
|
SMARCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
KPNA2
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
POU5F1
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PPP3CA
|
PPP3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
HGS
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CUL3
|
SPOP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
POLR2A
|
POLR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
TP73
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18034190
17346710
18421303
21245298
10559267
18418051
18644986
17521288
19067706
11748232
|
TP53
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
11278953
12203124
16931621
9582019
17693666
11118038
12433990
11395510
8183578
11429705
10400708
15242522
11423991
19067706
24336083
18381427
22732402
15988033
16341121
10935506
10094833
16215989
17280505
10744634
12851404
20673369
15851483
8845569
10559267
12168779
11850816
19505426
8564971
11756653
19054058
15566940
12173040
17690113
8635454
18034190
10510469
10101800
11335718
23100276
9400998
9445173
9582400
24098340
22532570
9122197
11420692
11104574
15679092
11748232
12560513
11928223
20400479
20546728
17145718
20567883
20840522
18172861
10566557
10777477
7834749
12806965
17521288
19242108
9000137
21859835
|
BID
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
20956295
17289999
25241761
19968986
15574335
10629050
19062087
10949027
12242151
23374347
14730312
17520191
8918887
|
MAPK8
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15525785
18471544
16709574
|
SH3GLB1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19074440
11161816
11259440
16189514
16227588
|
TP53
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14963330
16151013
7834749
|
TP53
|
BID
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12402042
16151013
18574470
|
MAPK8
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18594987
25326334
25077544
27374471
|
TP53
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15240700
12402042
18431400
15024076
|
HGS
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
STAM2
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
KIT
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11994499
16780420
12444928
17904548
|
CBL
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
FYN
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
97.0
|
1.0
|
Omnipath
|
9525940
7642581
8626543
7782294
15208330
16503409
16713569
10829062
10799548
10934191
8900205
8551236
8662998
8995358
19734451
12604776
9890970
10592173
17570479
10629042
17094785
10092522
11997497
12522270
15556646
12244174
8621719
9102067
22880054
9311917
11239464
19904769
11994282
12941616
9535867
25814554
12231245
15190072
|
CBL
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
9092574
17904548
25737303
8950973
15315962
17635922
10514377
|
CBL
|
RET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12727845
15677445
|
CBL
|
FLT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
25387128
18273061
17635922
10514377
|
CBL
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11847211
10025673
10648820
11850825
7782294
|
CBL
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
188.0
|
1.0
|
Omnipath
|
34609770
16105874
18273061
22239438
24797263
20332299
17635922
23158001
17545148
8662998
12604776
9890970
23153581
17182860
25872741
12593795
23175185
10092522
15107835
22266821
22833562
24714105
17242169
25140053
20124286
19531499
9756944
10086340
22203672
19225046
16729043
15282549
20562913
22394513
20940296
23331499
7592693
19713535
10635327
19836242
15465819
15210722
25521828
23897813
10514377
12734385
18508924
11994282
20877636
33323455
22976291
23774213
23027125
15159412
18255265
16246327
28541302
16849543
23799367
16713569
10799548
8798643
19155296
9121472
17486068
21772844
16969069
15677445
15962011
23418353
12803489
32714745
14505571
27903975
19578043
26177020
11239464
18319245
11408594
10428778
12061819
17995934
17971399
27059931
26055326
15735736
23457600
7782294
22591401
29629558
11370743
7657591
21071413
28198003
18316398
19947936
9130710
18271526
15657067
31182136
16923119
17880946
32904620
15117950
14627991
15668240
15383614
|
CBL
|
MET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
16397241
15123609
23331499
25241761
21222362
11894096
18672314
21163258
19450681
18273061
35309168
17533376
19433454
17635922
10514377
|
CBL
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
9234717
10347229
18988627
17635922
10514377
|
CAV1
|
EGFR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
11102446
17517963
18458534
19411448
20855962
21051947
21150282
21729786
22411312
22874531
23907124
25364523
26828520
|
TP53
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20190820
18359760
9664135
10029407
8152794
11713584
8887630
9285564
19597475
11546792
1586628
18604200
18391986
|
PDCD6IP
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
31980649
15456872
12771190
24658140
15557335
25402006
|
RIPK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11116146
|
SNX9
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
16316319
24658140
25402006
|
TGFB1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20953304
32103204
19132220
28943431
|
CBLC
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
10362357
22888118
17635922
10514377
|
EGFR
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17145710
23436906
7929151
21278786
24189400
23866081
17148612
12648464
27756321
18803307
10527633
10572067
22439932
|
EGFR
|
CALM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
17145710
19901323
20029029
12359306
16497976
25402006
17389395
18578522
16799092
20068231
3415247
7925415
18669648
12153558
24658140
17287340
14960328
18707149
17016520
|
EGFR
|
CALM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
19901323
20029029
16497976
15592455
25402006
17389395
18578522
16799092
20068231
7925415
3415247
8639568
18669648
12153558
24658140
17287340
2843348
14960328
15212693
18707149
17016520
|
EGFR
|
HGS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12953068
17016520
|
EGFR
|
SCAMP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
15144186
9658162
|
EGFR
|
HDAC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
20133936
31980649
22896792
20029029
24658140
21151618
25402006
23084749
|
EGFR
|
LRRK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
24947832
22337768
|
EGFR
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
21220489
24655521
23542172
29140271
28157503
26725162
22238610
25825764
17115032
26719139
28102297
22692198
28666590
25073158
20670598
20587074
23593472
25675097
|
EGFR
|
CAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17145710
31980649
22411794
9374534
19446582
16799092
12388423
15657067
24658140
19625610
16407214
18789131
25402006
15951569
10781609
16332692
|
EGFR
|
CALM3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
19901323
20029029
16497976
15592455
25402006
17389395
18578522
16799092
20068231
7925415
3415247
8639568
18669648
12153558
24658140
17287340
2843348
14960328
18707149
17016520
|
HGS
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
HGS
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
11094085
|
TP53
|
SFN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18281511
10101800
22427654
12640112
17404570
12447694
17361185
|
TP63
|
SFN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12640112
17404570
|
MAPK8
|
SFN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15071501
|
TP53
|
SFN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20206173
17546054
18431400
21340684
20066118
20457558
20182602
11896572
6396087
14517281
21625211
|
SFN
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21827211
12657644
12426317
15071501
|
RIPK1
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10465784
11274345
11668179
12048245
12556535
12655147
12738796
14730360
15170913
15592525
17462996
17496911
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23070005
23850759
24378531
26587781
26653790
28574505
28765050
9379049
9582321
|
RIPK1
|
TNFRSF1A
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10465784
11274345
11668179
12048245
12556535
12655147
12738796
14730360
15170913
15592525
17462996
17496911
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23070005
23850759
24378531
26587781
26653790
28574505
28765050
9379049
9582321
|
TNFRSF1A
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
14730360
15592525
17462996
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
|
TNFRSF1A
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12655147
21614932
12738796
11274345
18855897
|
TNFRSF1A
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
25681446
11002422
20547836
8612133
18450452
27552911
26802121
10356400
19773432
18621737
23815148
16611992
22179575
12721308
21741934
7538908
18949366
21113135
8985253
10744744
10795740
21119000
22733818
10755617
27321185
15115707
24098568
18939944
18329793
20825417
20448643
15357952
21737329
12887920
24130170
15258597
24758719
16115877
19524513
18724939
16968706
22817896
28817177
18022363
19815541
25388546
21331078
22848449
|
TP53
|
IGF1R
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
15131018
11001824
12089352
20633551
24205274
17097318
10023442
17600529
17014845
8710868
12444079
16181796
22033326
|
TP53
|
LITAF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10321740
21836606
17283168
15197774
|
TP53
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10321841
7915517
15358233
12217864
10516009
1705714
8570655
16980608
9707425
15950182
19789303
11313928
1356162
12384701
9858527
12947108
23390122
8524244
9651310
1352831
7909518
11032828
10910968
12485898
10618724
|
TP53
|
CAV1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10684646
20610713
17014845
11076533
|
TP53
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12732139
10618379
22264233
23706820
14514686
8183578
14761612
16138117
18593586
23063463
8119773
|
TP53
|
FLT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16432214
20080630
17242190
20422012
|
TP53
|
TP63
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
10606233
16931914
18388131
16516862
14576823
11382762
20442293
23019126
19858204
11238924
11423969
|
TP53
|
TNFRSF10B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10777207
10101800
11756185
11139340
15964798
22046379
10810622
14585074
19351839
11313989
10597242
17278883
|
TP53
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22607268
23376463
18374905
15958553
10854211
22353755
|
TP53BP2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
14985081
16139958
8875926
25502805
8016121
21513714
31515488
16713569
8668206
18275817
11839776
|
UBE2D1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15169778
15340381
15147722
12820959
10722742
19459846
18006823
10721693
19440234
|
RCHY1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
21988832
19483087
17568776
24367557
25116336
21084285
12654245
21791603
20452352
19043414
16713569
31630802
27519799
19918835
|
NUMB
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23881403
18172499
18492217
|
MAPK8
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
11108663
12531896
16713569
11283254
10706102
19651615
27147566
9724739
15538975
9732264
10581258
10436023
17570479
9393873
11896587
12514174
15580310
18813780
11078726
|
TP53
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11238924
18431400
16713569
|
TP53
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11238924
18431400
21508668
9891077
|
TP53
|
UBB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
18172499
18695251
24667498
22056774
17290220
17592138
12421820
18413597
20173098
19556538
21857681
17470788
18359851
19805293
19196987
12640129
|
TP63
|
JAG1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23863842
11641404
23837456
|
ITCH
|
TP63
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
16861923
23370280
16908849
25485500
20855944
22935697
|
TP73
|
TP53BP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11684014
18676979
14729977
18275817
|
YAP1
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
15678106
17110958
35044719
19111660
19788416
21808241
18280240
18640976
25283809
15893728
11278685
17889669
27292796
|
ITCH
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
15678106
11318614
10940313
17110958
17592138
21107885
19788416
21383157
18628966
16861923
11278685
|
ITCH
|
YAP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
10940313
11318614
16469705
16861923
18552861
18628966
21107885
21383157
|
AMOT
|
YAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
32755583
21205866
26269582
21808241
|
YAP1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
22921829
12118366
25283809
|
UBE2D1
|
MGRN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19549727
17229889
|
MAPK8
|
ATN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17081983
12812981
15302935
|
WWP1
|
RNF11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16713569
15231748
18724389
|
RNF11
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14559117
19131965
|
NUDT21
|
CPSF7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
16189514
25416956
|
KDR
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
CSK
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10790433
11181701
12485116
15713798
19290918
8011291
8986721
|
IGF1R
|
CSK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
10026153
|
PRKACA
|
CSK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
9224730
11181701
20826718
31125786
12600271
|
CSK
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
1985196
8262983
11489946
16537894
9647655
25720756
18691976
10366594
19369195
1533589
1699196
7524477
16713569
15713745
14967142
|
FYN
|
KIT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9038210
9799234
12374739
|
FYN
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16387660
17053785
|
FYN
|
CAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
9252391
29371975
11805080
12925753
21705803
12529448
11075810
15692085
14992595
8632005
10592173
16943184
12921535
16332692
12135605
20228056
15466865
33804982
24632723
33928090
18347068
34321069
|
RIPK1
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
IKBKB
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
20300203
9744859
17047224
11460167
17496917
14514672
|
MAP3K7
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10391247
11280761
11460167
11477091
12620219
14633987
14660645
15082531
15125833
16603398
16799562
17301840
17363905
18264787
18641653
19161412
20164171
21041997
21133840
21232017
22941947
23681101
24403530
24699077
24958845
|
SMAD6
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11737269
10748100
|
SMAD7
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12589052
|
TAB1
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16289117
18180283
10838074
24912525
23934659
10882101
19556242
11259596
19026643
14670075
17299140
23331499
22158122
12372426
21903422
17560374
21071413
23180781
19775907
14743216
17348859
20200282
26432169
18988627
10094049
8638164
11809792
10702308
25241761
19232515
14633987
18456659
10921914
20538596
15590691
16845370
27468689
12975377
12242293
17172402
22167179
12429732
12624112
12859960
16260783
11460167
|
MAP3K7
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
57.0
|
1.0
|
Omnipath
|
24911653
11129660
25195736
16006187
16260493
15502405
14530355
10779355
28159912
10094049
10837071
15836773
25659581
10195894
9689078
17363973
10807933
15214841
16186825
16493424
10022904
18316610
10187861
12547194
33895773
28475177
16301747
15691841
15620648
15327770
29748387
19632174
11460167
17965022
|
MAP3K7
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15692051
17947236
11865055
17965022
17186025
|
MAP3K7
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
11477091
17301840
13130464
18855897
15125833
24699077
9278437
17363905
18641653
24403530
20060931
21133840
21614932
9891069
12738796
21232017
9851932
18264787
10391247
16799562
23109003
12620219
14633987
12709432
8177321
19161412
22941947
23681101
12556533
11280761
15082531
26192618
14660645
24958845
20164171
11460167
16603398
21041997
11274345
|
RIPK1
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
10521396
11003656
11274345
1134007
11583996
12215447
12702723
12724420
12887920
15592525
15760909
16469705
16498403
16940415
17462996
17603935
18570872
18621737
18641653
19037093
19131965
19498109
19524512
19524513
19597341
19632174
19838173
19935698
20125124
20531300
20823910
20861672
21133840
21232017
22265414
22421439
22427918
23010170
23069999
23073834
23377657
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
26972597
27558815
27833036
27959630
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK1
|
MLKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
53.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16469705
16498403
16940415
17462996
17603935
18641653
19037093
19498109
19524512
19524513
19597341
19632174
19838173
20531300
20823910
20861672
21133840
21232017
22265414
22421439
22427918
23010170
23069999
23073834
23377657
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
26972597
27558815
27833036
27959630
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK1
|
CFLAR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
48.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK1
|
MLKL
|
â—¼ SHARES_COMPLEX
|
|
|
53.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16469705
16498403
16940415
17462996
17603935
18641653
19037093
19498109
19524512
19524513
19597341
19632174
19838173
20531300
20823910
20861672
21133840
21232017
22265414
22421439
22427918
23010170
23069999
23073834
23377657
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
26972597
27558815
27833036
27959630
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK1
|
CFLAR
|
â—¼ SHARES_COMPLEX
|
|
|
48.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK1
|
RIPK3
|
â—¼ SHARES_COMPLEX
|
|
|
60.0
|
1.0
|
ACSN
|
10521396
11003656
11274345
1134007
11583996
12215447
12702723
12724420
12887920
15592525
15760909
16469705
16498403
16940415
17462996
17603935
18570872
18621737
18641653
19037093
19131965
19498109
19524512
19524513
19597341
19632174
19838173
19935698
20125124
20531300
20823910
20861672
21133840
21232017
22265414
22421439
22427918
23010170
23069999
23073834
23377657
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
26972597
27558815
27833036
27959630
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
ITCH
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10940313
11318614
16469705
16861923
18552861
18628966
19131965
20068034
21107885
21383157
|
RIPK1
|
RIPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
60.0
|
1.0
|
ACSN
|
10521396
11003656
11274345
1134007
11583996
12215447
12702723
12724420
12887920
15592525
15760909
16469705
16498403
16940415
17462996
17603935
18570872
18621737
18641653
19037093
19131965
19498109
19524512
19524513
19597341
19632174
19838173
19935698
20125124
20531300
20823910
20861672
21133840
21232017
22265414
22421439
22427918
23010170
23069999
23073834
23377657
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
26972597
27558815
27833036
27959630
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK1
|
MLKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
53.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16469705
16498403
16940415
17462996
17603935
18641653
19037093
19498109
19524512
19524513
19597341
19632174
19838173
20531300
20823910
20861672
21133840
21232017
22265414
22421439
22427918
23010170
23069999
23073834
23377657
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
26972597
27558815
27833036
27959630
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK1
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
14730360
15592525
17462996
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
|
RIPK1
|
CFLAR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
48.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
TNFAIP3
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
20448643
17703191
18246070
15258597
19131965
|
RIPK3
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
11734559
21903422
22265414
19524512
19524513
22817896
26559832
10339433
26319693
11585904
22265413
|
CFLAR
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12887920
11002417
17047155
10837247
|
RIPK1
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12655147
21614932
12738796
11274345
18855897
|
SMAD3
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11279127
11792802
12702545
12809600
15265520
16179589
16713975
18768831
21042762
21614932
22331441
23784029
8515656
|
SMAD2
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11074002
11279127
15265520
16179589
16713975
21042762
21614932
22331441
23784029
9670020
|
SMAD7
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
11279127
15265520
22286770
23784029
|
SMAD2
|
SMAD7
|
â—¼ PROTEIN_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
11074002
11279127
15265520
16179589
16713975
21042762
21614932
22331441
23784029
9670020
|
SMAD3
|
SMAD7
|
â—¼ PROTEIN_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11279127
11792802
12702545
12809600
15265520
16179589
16713975
18768831
21042762
21614932
22331441
23784029
8515656
|
SMAD7
|
TGFBR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11279127
15265520
22286770
23784029
|
SMAD2
|
SMAD7
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
10.0
|
1.0
|
ACSN
|
11074002
11279127
15265520
16179589
16713975
21042762
21614932
22331441
23784029
9670020
|
SMAD3
|
SMAD7
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
11279127
11792802
12702545
12809600
15265520
16179589
16713975
18768831
21042762
21614932
22331441
23784029
8515656
|
TGFB1
|
SMAD7
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
11133108
11708773
12490555
14557817
15111329
15181457
15252039
15548370
16474430
16607286
16716598
17615296
17934056
18403754
19010789
19109155
19920116
20519943
20644162
21041997
21278795
21900405
21909923
22703233
7594497
9157999
9335507
|
SMAD3
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10823886
15183844
12761881
10887185
10973944
10839991
10753944
10843994
15579469
10559222
|
SMAD2
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15183844
10887185
10753944
10843994
10559222
|
SMAD7
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10887185
15855807
9886263
20631490
22656308
19214138
23633623
14600158
10753944
11912247
11385614
11180003
17928287
19010789
22496417
22841502
17074765
15496141
11448947
|
ITCH
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
21071413
19030025
15946939
|
TGFB1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19010789
14718519
16474430
17934056
20519943
9335507
21900405
11133108
14557817
15548370
19920116
|
WWP1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
15221015
|
SMAD7
|
TAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
11737269
|
SMAD7
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
21071413
9892009
26555259
9892110
|
SMAD7
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
9335505
21897371
9335507
17314099
12151385
9892110
23331499
22921829
21071413
21791611
18988627
11278251
16571110
14657019
18725536
15761153
11163210
15221015
30017632
22286770
15148321
20663871
14722617
9215638
|
SMAD7
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
17438144
21071413
9892009
9892110
|
SMAD3
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013220
11074002
11279127
11283613
11283614
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21252118
21614932
2191300
22331441
23140366
23338822
23869868
8515656
9312026
9389648
9618481
9670020
9865696
|
SMAD3
|
SMAD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013220
11074002
11279127
11283613
11283614
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21252118
21614932
2191300
22331441
23140366
23338822
23869868
8515656
9312026
9389648
9618481
9670020
9865696
|
TGFB1
|
SMAD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
TGFBR1
|
SMAD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
14557817
15265520
16474430
17934056
20060931
20519943
21614932
22703233
24132110
24336330
|
TGFB1
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
15548370
19010789
10678166
16474430
9311995
23831640
17934056
20519943
24075003
11792802
11133108
21900405
14557817
11278410
19920116
9865696
|
TGFBR1
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
10678166
12220225
9892009
9463378
16024789
9136927
14625308
11792802
11133108
19920116
14557817
11278410
15134444
10085140
23331499
21071413
20060931
17934056
18511908
21614932
18988627
10973958
23221174
8980228
9311995
9346908
9235954
20519943
21900405
15350225
15548370
26057631
19010789
15104092
16474430
9346966
30093905
12957874
11744690
9525694
15212693
11274345
9865696
|
SMAD6
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
9256479
21071413
9892110
|
WWP1
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
15221015
15946939
15359284
|
SMAD2
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
21988832
26186194
12543979
9111321
15084259
9311995
25878769
18729074
12700238
|
TGFB1
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
TGFB1
|
SMAD3
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
TGFBR1
|
SMAD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
14557817
15265520
16474430
17934056
20060931
20519943
21614932
22703233
24132110
24336330
|
TGFB1
|
SMAD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11278410
11792802
12154066
12717440
12724770
14557817
15265520
15548370
16474430
17934056
19010789
19050695
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22703233
22710166
24132110
24336330
7594497
9311995
9865696
|
SMAD3
|
GLI1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
11013125
11074002
11279127
11376132
11792802
12702545
12809600
15265520
16179589
16713975
18768831
21042762
21098712
21614932
22331441
22652804
23784029
25374926
8515656
9389648
|
SMAD3
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26553048
27974707
10708950
19214138
|
TGFBR1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
15104092
9311995
8774881
25714018
11438668
19458083
11792802
12957874
19701891
9380693
|
KPNB1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11294908
10846168
|
MAPK8
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10601313
25714018
|
TGFB1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21557273
24899689
24075003
24485922
28756206
32196115
|
SMAD3
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
16713569
14638857
18988627
|
TGFB1
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR1
|
â—¼ SHARES_COMPLEX
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
22326956
10187774
7852346
22703233
12809600
7706250
11323414
8047140
8235612
26194464
|
TGFB1
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
19010789
16474430
17934056
18403754
20519943
16607286
21900405
11133108
14557817
15548370
19920116
|
DTX1
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
11153911
20208568
23331499
21071413
11226752
11564735
22162134
18988627
|
NOTCH1
|
NUMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
NOTCH1
|
JAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
NOTCH1
|
NUMB
|
â—¼ PROTEIN_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
NOTCH1
|
JAG1
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
NOTCH1
|
NUMB
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
NOTCH1
|
JAG1
|
â—¼ LOCALISATION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
NUMB
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
12682059
15358736
16713569
8755477
|
ITCH
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12682059
10940313
23331499
16713569
|
JAG1
|
NOTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
18495817
16921404
15137944
769772111006133
16713569
23331499
21071413
23086448
22363130
18988627
21820430
18292500
18660822
22330899
17537801
11006133
7697721
10958687
22353464
|
JAG1
|
NUMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
JAG1
|
NUMB
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
JAG1
|
NUMB
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
21.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
16039586
17143292
17936032
19567869
19619488
20351093
20705860
20940030
21841793
22330899
22363130
22363487
23343194
24023259
25730849
7542250
8666229
|
TGFBR1
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
11274345
12738796
14557817
15265520
15282297
16200688
16474430
17934056
18855897
20060931
20519943
21614932
22703233
23070005
24132110
24336330
24403530
|
CAV1
|
TGFBR1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
11102446
17517963
18458534
19411448
20855962
21051947
21150282
21729786
22411312
22874531
23907124
25364523
26828520
|
SMAD6
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
11278251
23331499
22921829
9335505
21897371
22286770
20663871
9335507
15761153
12151385
11163210
9215638
9892110
|
PPP3CB
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
18287025
19136967
19836308
21278340
21709260
21983832
7650486
8068174
9374532
9973469
|
PPP3CB
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
18287025
19836308
21709260
21983832
7650486
8068174
9374532
9973469
|
PPP3CB
|
KPNB1
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
18287025
19136967
19836308
21278340
21709260
21983832
7650486
8068174
9374532
9973469
|
PPP3CB
|
LRRK2
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
18287025
19836308
21709260
21983832
7650486
8068174
9374532
9973469
|
PPP3CB
|
LRRK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
18287025
19836308
21709260
21983832
7650486
8068174
9374532
9973469
|
PPP3CB
|
TAB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10089876
10391247
11274345
11796223
12620219
14660645
14741051
15036616
15082531
17593948
18235236
18264787
18855897
19136967
19608982
23070005
2550447
7650486
9973469
|
UBE2M
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
19617556
18826954
25349211
23912815
25314029
18206966
21940857
23201271
26906416
19250909
30610225
25531226
|
SPOP
|
CUL3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
21988832
23331499
19256485
28216678
21577200
25011449
34599168
22911784
15897469
22013077
16524876
19261606
25278611
|
RIPK3
|
MLKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
55.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16469705
16498403
16940415
17462996
17603935
18641653
19037093
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
20823910
20861672
21133840
21232017
22265414
22421439
22427918
23010170
23069999
23073834
23377657
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
26972597
27558815
27833036
27959630
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
CFLAR
|
MLKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
CFLAR
|
MLKL
|
â—¼ SHARES_COMPLEX
|
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
RIPK3
|
MLKL
|
â—¼ SHARES_COMPLEX
|
|
|
55.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16469705
16498403
16940415
17462996
17603935
18641653
19037093
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
20823910
20861672
21133840
21232017
22265414
22421439
22427918
23010170
23069999
23073834
23377657
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
26972597
27558815
27833036
27959630
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
CFLAR
|
MLKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
RIPK3
|
MLKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
27826146
24434512
25493335
26024392
28126382
26866270
34155344
27959630
24901049
27832137
26184911
30029665
26967968
29026104
24703947
28807105
27941671
23612963
24012422
29484439
22265413
|
RIPK3
|
CFLAR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
RIPK3
|
CFLAR
|
â—¼ SHARES_COMPLEX
|
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
RIPK3
|
CFLAR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
TNFRSF10B
|
CFLAR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15024054
20696707
19278658
10837247
19416807
21235526
|
ITCH
|
CFLAR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10940313
11318614
16469705
16861923
18552861
18628966
21107885
21383157
26972597
|
ITCH
|
CFLAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
30736843
16469705
19090833
18786561
|
LRRK2
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
14627704
17593948
17662023
18287025
19836308
21709260
21983832
7650486
8068174
9374532
9973469
|
LRRK2
|
KPNB1
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
14627704
17593948
17662023
18287025
19836308
21709260
21983832
7650486
8068174
9374532
9973469
|
TAB1
|
KPNB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10089876
10391247
11274345
11796223
12620219
14660645
14741051
15036616
15082531
17593948
18235236
18264787
18855897
19136967
19608982
23070005
2550447
7650486
9973469
|
LRRK2
|
KPNB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
14627704
17593948
17662023
18287025
19836308
21709260
21983832
7650486
8068174
9374532
9973469
|
LRRK2
|
SH3GL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
25501810
24778241
22998870
|
SMAD6
|
TAB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
11737269
|
TAB1
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20060931
21614932
12738796
11274345
18855897
|
NUMB
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
ACSN
|
10940313
11318614
16469705
16861923
17115028
17312394
18552861
18628966
20818436
20940030
21107885
21383157
|
NUMB
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
12.0
|
1.0
|
ACSN
|
10940313
11318614
16469705
16861923
17115028
17312394
18552861
18628966
20818436
20940030
21107885
21383157
|
NUMB
|
GLI1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
10940313
11318614
16469705
16861923
17115028
17312394
18552861
18628966
20818436
20940030
21107885
21383157
|
NUMB
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12682059
23331499
20818436
18628966
|
NUMB
|
GLI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18552861
17115028
20818436
20940030
17312394
|
ITCH
|
GLI1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
10940313
11318614
16469705
16861923
17115028
17312394
18552861
18628966
20818436
20940030
21107885
21383157
|
GLI1
|
PTCH1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11001584
11960000
12138125
14555646
15087129
15520176
16054035
16158046
16328026
16396903
16406505
16571352
16880536
17000779
17035233
17638910
18754008
18813803
19081070
19190345
19219074
19736394
20107231
21059263
21442356
22354771
23031257
|
GLI1
|
PRKACA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
17283082
16421275
19056373
16705181
|
GLI1
|
PTCH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19860666
21076395
11719506
16571352
15087129
|
PRKACA
|
GLI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16481469
23331499
20027184
16293631
19996099
|
MTSS1
|
GLI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15545630
23331499
17845852
|
ITCH
|
GLI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
18552861
17115028
20818436
20940030
17312394
|
GLI1
|
PTCH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
16158046
18813803
19219074
16880536
21059263
11960000
19190345
15087129
21442356
16328026
19736394
11001584
12138125
20107231
15520176
16406505
17000779
16571352
16396903
14555646
17035233
16054035
|
CAV1
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
18988627
16189514
10066366
|
PCBP2
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19881509
|
N4BP1
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17592138
|
SPART
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16055720
19580544
19307600
19765186
20504295
|
MAPK8
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23435430
16469705
15358865
16446428
|
ITCH
|
MAVS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
19881509
27736772
|
ITCH
|
SPART
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16055720
19580544
20719964
19307600
19765186
20504295
|
ITCH
|
SH3GL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
14684745
17038327
26613292
|
ITCH
|
ERBB4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18334649
17463226
|
IKBKB
|
CYLD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
19481526
24614225
15870263
|
CYLD
|
DDX58
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18467330
18636086
|
TAX1BP1
|
TNFAIP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
18246070
34454289
20599425
23018911
32296183
10435631
18239685
11389905
|
MAVS
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17145710
16177806
16153868
21903422
17468758
18207245
|
PRKACA
|
CFTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
28003367
23060444
25867080
21455600
30600261
1716180
28242698
19328185
32102849
92316961
19095655
14602047
7530719
10581361
11053017
9385646
25330774
15657296
1377674
|
PRKACA
|
RET
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20682772
15966897
17050626
11886862
|
PRKACA
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9461522
24003153
10753752
11146000
2987243
27481942
27646272
|
DDX58
|
TRIM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
19017631
20403326
24755855
19484123
17392790
|
TRIM25
|
DDX58
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
20406818
30902577
20818395
24478431
34471099
23950712
34452305
34529741
18353649
35075101
18948594
27122586
32513696
17392790
|
RNF135
|
DDX58
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19017631
23950712
19484123
35089988
|
DDX58
|
MAVS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
61.0
|
1.0
|
Omnipath
|
17145710
20554965
16127453
33372174
20007272
35075101
21419663
16585524
20406818
19052324
17020950
21903422
19164550
24478431
17190814
16713980
18200010
18948594
19193793
16177806
34544279
16153868
23843640
16785313
16301520
21844353
16125763
19036819
18977754
21102435
33976430
22301138
17709747
21200404
29263274
26494172
23499489
18207245
19881509
22844514
20080758
|
MAP2K4
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
17143273
10713157
11489946
7600581
8702918
17145710
13130464
23416355
10748139
8805275
18855897
10791986
9108083
19690332
95141073
18083107
9724739
12788955
9305638
23331499
19534553
15068801
7839144
10958661
21071413
23047924
11062067
21614932
9808624
12738796
15911620
15998799
9891069
11389443
18988627
9733714
11847100
18669648
16153436
10521444
15302099
16282370
11242034
14523011
12709432
26370088
9661668
10499589
7652575
16076903
7992057
16440308
7600582
17192257
9860979
15755722
12133933
16533805
19369195
9312068
9207092
10385525
12354380
12917261
8910292
9487126
9448004
10962008
12624093
11274345
11099046
|
ARRB2
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
23208550
17148612
17666399
24658140
27226565
2163110
24561123
22364396
|
STAM2
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
STAM2
|
MET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
MET
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
STAM
|
SH3GL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
RET
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18669648
9312068
11062067
15911620
95141073
16153436
15755722
|
MAPK8
|
WWOX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15580310
12514174
18371080
|
MAPK8
|
JUNB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8917518
18669648
9889198
20068231
9405416
|
IFIH1
|
MAVS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
19416887
22301138
17600090
17020950
19052324
21903422
16410796
16785313
16713980
23499489
16127453
33372174
16125763
|
SF1
|
EWSR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9660765
16713569
|
NRG1
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10970856
16843264
7514177
7592681
23331499
8702572
7477375
11555649
9565587
16189514
26148232
9168115
9275162
10214951
17697999
|
NRG1
|
ERBB4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
23331499
9275162
7721889
25052836
10970856
10214951
8062828
9565587
14967450
10537356
9168115
|
POLR2A
|
POLR2C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
POLR2B
|
POLR2C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
TRIM25
|
TRIM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
19017631
20403326
24755855
19484123
17392790
|
TRIM25
|
RNF135
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
19017631
20403326
24755855
19484123
17392790
|
POU5F1
|
SOX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20505756
12136102
17324942
15988017
17068183
|
SPART
|
WWP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19765186
19580544
19307600
|
RNF135
|
TRIM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
19017631
20403326
24755855
19484123
17392790
|