Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SMAD3 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11906909 16603637
BAX GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0912742107 20080742
ITPR1 BCL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0907555106 19706527
DDIT3 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15836916 20398749
RUNX2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17517365 23073173
BCL2 MAPK8 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15733859 5217553
DDIT3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17652152
JUNB BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11163237
BCL3 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15465827 16148099
BCL3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12907458 16732314
FOSL2 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22493372
BCL6 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11920165 11341761
BCL6 IL9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24879792 24550509
CREB1 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9926942 6548521
JAK1 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213490 11163768
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
YY1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21666725
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
FOSL2 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23339184 17434164
SMAD3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19768112 15735739
YY1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22025288 18558095
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
HMGA2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20074583 18957199
FOSL2 DDIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DDIT3 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18649942 15829559
DDIT3 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18794136 19074988
FOS DDIT3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
DDIT3 ATF3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TCL1A EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810965105 19064921
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
EP300 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24229708 15138260
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828133 24058639
UBE2I IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14651848 16906147
SET IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FADD IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16227629 23131831
KAT2B IRF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10022868 11304541
ESR1 MAPK12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16885352 22399296
MAPK14 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29057206 20551513
MAPK14 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18253836
YY1 NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16170350 9092633
TDG SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TDG PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129768
YY1 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8990171 10804019
YY1 GNAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18458536
YY1 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7838721 8524292
YY1 POSTN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21839814
YY1 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18495079
JUN COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8621730 12384935
JUNB COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19561194 7876214
ATF3 ATF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23850759 26587781
ATF3 ATF4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 23850759 26587781
ATF4 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20617572 19648113
ATF4 PTH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18187540 19851510
EGR1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24337575 18281687
IRF1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11888675 21760952
ATF3 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24420912 26554515
ESR1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20404154 17932106
IRF1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12817009 28166218
JUNB IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15699140 28100679
SMAD4 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14557415 21728174
GATA3 IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20154735
MAF IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15749884
CREB1 IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
SMAD4 IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20154735
TCL1A JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810965105 19064921
TCL1A FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810965105 19064921
TCL1A JUNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810965105 19064921
CREB1 TCL1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
TCL1A JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19064921
CRKL MAPK8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7033842 16982329
CRKL IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11443118 11124936
FOS BATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12087103
JUN BATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12087103
BATF3 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12087103 10878360
GNAI3 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8327893 19703466
FOS HPGDS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8617242 8206948
JUN HPGDS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8617242 8206948
FADD FAS â—¼   COLOCALIZATION 2.0 0.8 intact 16498403 5218359
CREB1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17464208 18471910
FOS VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12163680 11353786
GNAS ADCY4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
SMAD4 JUNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
FOS SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11854297
DMTF1 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21421563
SMAD4 ZFP36 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12754205
CREBBP SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9679056 9679060
SMAD4 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9679056 9679060
SMAD4 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9689110
IL1R1 IL1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221365 9062193
IL11 JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7957045 8637716
IL4 JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12223527 23124025
IFNGR2 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15120645 23331499
EGR1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21283769
FOS PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11774399
SMURF1 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PRKACA SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD3 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0712044105 18268325
SMAD3 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20869563 16018191
SMAD3 ZFP36 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12754205
SMAD3 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11331591 21612856
CREB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16862174
BCAR1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18321991
SMAD3 FOXP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19701891 15367216
SMAD3 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11790301
ESR1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10935492 12878732
JUND MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20816750 9136992
RUNX2 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19915614 16166639
JUNB MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18976709 20816750
MMP1 MMP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 7780967 1371271
CREBBP MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15894584
ESR1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12603855 26790618
FOXP3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19797626 24315995
CREB1 IL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
CYBA NOX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12716910 16762923
HRAS FOSL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS FOSL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
ITGB3 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16581250 8649368
EGR1 BCAR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22431919
RUNX2 SMURF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24631292 23042144
JUN MAPK8 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
JUN MAPK9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
JUN CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18196534 17922191
JUN RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11604227
JUN CFLAR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17070520 17332355
JUN MGP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11425864
JUN IL13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21989417 15494506
JUN DMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15601844 12489182
JUN JUND â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8922393 2504580
JUN CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19299558 23250032
MAPK9 JUN â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19527717 7148309
FOS FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10903433
MAPK8 CFLAR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18471544
JUND NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11905996 7969116
IL1B CASP8 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 1574116 22267217
BIRC2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17145710 12887920
CASP8 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11002417
CASP8 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11002417
CHUK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12799363 23430059
CHUK IKBKB â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 12799363 23430059
CHUK IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12351658
FOSB IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7989759 9171236
FOSL1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1737937 11385624
CREB1 IL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
JUNB IL13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12956740 25861992
CSF2 PRKACA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10477722 10949031
GZMB CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15569669 8755496
GJA1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11035005 5213074
SRC FCGR2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC FCGR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17160021 22105363
IRF1 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21219575 18641303
CREB1 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24298014 17591856
FOXP3 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23201402 20554955
FOXP3 FCGR3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20554955 19494275
ESR1 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15217907
JUND ITGB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23319049
JUND IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23398888 14686613
JUND PENK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8152431 1719551
JUND MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12226747 21734453
DMTF1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19816943
EGR1 IGF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12384981
ATF3 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24951825 19097984
IRS1 IRS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11912194
IGFBP3 IGFALS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9497324 9446566
FOS EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21239258 1918021
FOS CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19022561
UBE2I FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16055711 16236267
FOS EDN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9588211 16716598
HMGA2 FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9690519 9311991
FOSL1 ITGB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23319049
ESR1 MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22927007 24374826
MMP3 DCN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9148753
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
IRF1 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22182512 19056926
IRF1 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10751398 23271966
IRF1 CASP7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10918594
MAF IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12421951 17892401
CREB1 SOX9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17289023
CREB1 ADCYAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16006741 24018543
CREB1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16497991 16651461
CREB1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16293792 22890843
MAPK8 IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17050683 18029441
PDLIM7 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD1 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12082094 12151083
SMAD1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19664780 24692107
SMAD1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
SMAD1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17215250 22298955
SOX9 RUNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605170103 17142326
SOX9 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19306868 20593410
PGR ADCYAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11027674 10537148
PRKACA CACNA1D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19074150
GNAQ GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20399743
FOSL2 IL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12929935 9488674
GSK3B FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20154735
ESR1 NOS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17921256 0704315104
ESR1 EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10432218 18414489
ESR1 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16262660 7479947
ESR1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18313050 19861308
ESR1 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11477071
ESR1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9259323 8625613
ESR1 ITPR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19515975 23884412
PRL ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25193864 19524120
TBX3 NPPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15158141 18444963
MAPK8 ATF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25301550 26538579
IRF9 IL27 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20083668
PGR GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19423654 22669741
MMP2 DCN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9148753
CASP7 ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17178732
RUNX2 MGP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19306294 19896523
PGR GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15046957 7113584
DMTF1 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19816943
JUNB DMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15601844 15308641
ACP5 MAPK9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAPK8 MAPK9 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
ATF4 CREBBP â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
BRCA1 SMAD3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19768112 15735739
JUNB EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15308641 17510411 21937452
IRF1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10438822 14662860 15509808 23670564
JUN ATF3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 10327051 6546308
GSK3B SMAD1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25241761 18045539
BRCA1 FOSL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25184681 29656893
DDIT3 ATF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 20102225
SMAD3 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22995475 15009097 11058129 15994459
BATF3 RAD18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
JUNB RAD18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IRF9 RAD18 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BATF3 ATF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR1 FAS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
FOSB JUND â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10942775 33961781
FOS ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
FOS TRIB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 25609649
DET1 STK40 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
JUNB CREB5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FOSB CREB5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 33961781
JUNB DET1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FOS STK40 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
BRCA1 RAD18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29656893 25184681 23901102
DDIT3 JUNB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
DDIT3 FOSL2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 16189514 25416956 20102225 27107012
CCNA2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MAF ATF4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
FOSL1 ATF4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 1827203 23661758
UBE2I SMAD4 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217094 15231748
SMAD4 JUN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10220381 25609649
JUN JUND â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25609649
CREB5 JUND â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FOS DET1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 35140242 33961781 26186194
JUNB STK40 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28089446 33961781
FOSL2 STK40 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28089446 33961781 26186194
FOSL2 DET1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FOSL2 TRIB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ESR1 JUNB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11477071 31527615
FOSL1 CREB5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 33961781
CREB5 ATF7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
EP300 IRF1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
IKBKB SRC â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ATF4 FOS â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
DDIT3 CREB3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 23661758 20102225
EP300 FOS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19064921 21937452 11287611 24069158
JUNB ATF4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23661758 21988832
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
ATF3 ATF7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30833792 20102225
RUNX2 SMAD1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10531362 10962029 17215250 20851880
ESR1 SET â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
BATF3 JUN â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
FOSL1 JUNB â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
KAT2B SMAD3 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
FOXP3 IL2 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
EP300 SOX9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15623506 35140242 12732631 19828133
EP300 SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10205054 20851880 22365546 16613856 10673036
BATF3 ATF3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23661758 20211142 12805554 20102225
MAPK8 JUN â—¼   PHOSPHORYLATION ✅ 0.85 0.85 mint 7148309 19527717
CASP10 FAS â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
TRIB1 STK40 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 26186194 25852190 32707033
TRIB1 DET1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
EGR1 EP300 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
ATF7 JUN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RUNX2 SMAD1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CASP8 BCL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16183855 11406564
JAK1 BRCA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 11163768
SMAD4 EP300 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 25514493 18215124 9843571 14612423 10887155 22033265
ATF4 EP300 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14630807 17872950 10350644 12471036 16219772
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
CREB1 JUN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 2138276 25609649
MAF FOS â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21163924 8108109 23661758
ESR1 FHL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15666801 31527615
ESR1 DNM1L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19805454 21217774
BIRC2 CASP8 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
EP300 RUNX2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
FOSL2 STK40 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
MAPK9 JUN â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 9405416
BCL2 ITPR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19706527 15613488
CCNA2 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25091198 16713569 9244350 10373534
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
BATF3 CREB5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
BATF3 JUND â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 20102225
ITCH JUN â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
JUN FOSL2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 25609649
ITCH JUN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17110928 16901904 19818398 19806201
CASP8 BIRC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12887920 27810922 15069192 22274400
FOS CREB5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956 33961781 26186194
FOS STK40 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 33961781 25609649 26186194
FOSL2 CREB5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956 33961781 26186194 27107012
FOSL2 ATF7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26496610 33961781 26186194 20102225
DNM1L GSK3B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 9731200
JUNB ATF7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 20102225
BATF2 JUNB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23661758 21988832
BRCA1 CREBBP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
FOSB JUND â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ATF7 FOSL2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
IGF2 IGFBP3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CREBBP TDG â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CASP10 CFLAR â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATF7 FOS â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATF3 DDIT3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DDIT3 FOS â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BIRC2 IKBKG â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HRAS NF1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CHUK CREBBP â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CREB5 FOS â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
STK40 TRIB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ATF7 CREB5 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
IL10 YY1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CFLAR ITCH â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
DDIT3 ATF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18330356 16189514 23661758 12805554 20102225
DDIT3 BATF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32296183 25416956 23661758 20211142 20102225
FOS ATF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 25241761 23661758 1827203 20102225
SMAD4 JUNB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 10220381 15231748
IL1R1 IL1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7878046 9062193
GSK3B SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21310903 18172167
FOS SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21829441 9732876
BATF2 JUN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19074269 23661758
JUNB JUND â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
ESR1 GATA3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
CASP7 BIRC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16339151 30948266 9384571
CASP10 CASP8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CREBBP KAT2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
BCAR1 CRKL â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
GNAI2 GNAI3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CREBBP SMAD3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CREBBP JUN â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
JUN BCL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 10497212
JUND BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12080089 16713569
JUN DDIT3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10523647 23661758
CREB1 EP300 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
KAT2B EP300 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8684459 12888487 9267036 12419806 21413932 22384255 20870727 33051058
KAT2B IRF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10022868 23670564 11304541
TDG ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12874288 16282588
BCAR1 CRKL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9498705 8810278 10753828 22974441 8978305 18835194
BATF3 JUNB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23661758 20211142 33961781 20102225
ATF3 SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 12718878 20930144
SMAD3 RUNX2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10531362 10962029 21986102
SMAD3 JUNB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 10220381 10903323
RUNX2 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11641401 11274169
JUN ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17317669 11477071 16713569 23747343
JUN ATF7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25609649 26496610 20102225
CFLAR ITCH â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19808964 30736843 18559494 33631302 19090833 31443721 33469115 21474069
FOSL1 JUND â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 24029232 26258633
RUNX2 FOS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11641401 11274169
ATF3 JUNB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 23661758 33961781 20102225 30833792
CASP7 BIRC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16339151 9384571 11084335 33961781 15580265 19258326
CDKN2A NPM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
SMAD4 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15886208 16603637 18620728
AKT3 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14766748 15642728 17525161
JUN BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14623928 17262823 19335069
BCL6 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21106671 12594267 15507530
EP300 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17828269 12402037
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
EP300 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 19887647 10655477 11782371 16713569 21212407 22787115
JUN BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12080089 25609649 16713569
JUNB BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16713569 25184681 12080089 33961781 18259752
BRCA1 FHL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14986435 25184681 14550570 21988832
CREB1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
CREB3 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
GATA3 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
FOS DDIT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 31467278 23661758 26264872 29997244 32814053 10523647 20102225
ATF3 DDIT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 31467278 23661758 20211142 26264872 29997244 32814053 33961781 8622660 20102225 27107012
JUN DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19299913 22622069 12069855
DDIT3 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18940792
DDIT3 FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10523647 16189514
EP300 EGR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15225550 9806899 20089040 20018936
EP300 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27956703 21268080 21937452 24069158 11689449 14630807 11980644 10327051 12437352 12471036 24636898
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
EP300 IRF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15509808 10438822
EP300 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20851880 22298955 12697832
IKBKG IKBKB â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 8209688 506093200 16126728
MAPK14 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15649893
CREB1 SMARCA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16675956 20864035
TDG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12874288 17129768
YY1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9238849 21852380
YY1 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9199306 7494244 12296377
EGR1 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12729460 16702209 11169739
ATF4 ATF3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19164757 16189514 23661758 20102225
ATF4 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 1827203 20936779 23661758
JUN IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15699140 25567680 28100679
CRKL MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 9710592 16982329
BATF3 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23661758 10878360 33961781 25609649 20102225
JUND SAT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20460526
ITGB3 VEGFA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12820653 19267251 17030947
SRC VEGFA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
GNAS ADCY8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
SMAD1 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 17183365 16189514 32296183 31467278 12167862 14701756 12874272 28468752 15761153 24412244 10531362 15231748 11700304 11779505 26555259 9436979 21454478
SMAD3 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 16189514 25514493 11927552 28443643 21988832 20211142 15084259 12732634 19768112 15467747 20142324 25609649 15922743 12917407 12419246 20564330 24382352 19139564 32296183 24157709 18729074 22442258 10092624 17283070 15350224 17591701 15761153 31591477 10995777 26555259 9892009 9311995 15588252 12167862 10878024 25910212 27703004 33990575 28115363 18055455 22310290 19135894 10531362 12794086 15231748 21297662 22045334 19917253 24584437 27107012 29892012 29997244 21532621 27845895 21597466 25502805 11114293 12543979 23788427
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
SMAD4 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278818
IL6 JAK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8134389 8272873 9382798
JAK1 IL27 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14764690 27119567 24771852
GHR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 10502458
SERPINE1 PLAU â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11021826 20027185 25502501
SMAD3 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10903323 11306568 10220381 9732876 21829441
SMAD3 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15086314 23161884 16619037
SMAD3 IL9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26365427 22503540 23913959
SMAD3 APOC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10995777 11229886
SMAD3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
SMAD3 SOX9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15623506
ATF3 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10760799
FOSL1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19687301 20386569 11028561
SRC BCAR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 604342200 7033822 17038317
CREB5 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 26496610 8440710 33961781 25609649 26186194 24981860
JUN GZMB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath
JUN PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14684847 12446585
JUN IL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12929935 15546613 9488674
CREB5 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8378084 8440710
CASP8 CFLAR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22322857 24438025 12097160 33469115 19416807 22864571 9208847 9326610 17159907 11741985 15280356 19710364 21737330 31046799 21737329 9289491 17047155 9228018 12887920 9380701 33961781 26186194 12215447 19343040
IKBKB NGF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8837778 11244088 8599092
GZMB CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19103589 15569669 17283187
AKT3 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19609947
CREBBP IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17923090
JUND IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1737937 7989759 11685114
IRF1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15659847 10570299 15355347
CREBBP IRF9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8848048 17923090
FOS IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7665092 10772943 9133600
IRF1 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12479817 25280793 19556165
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
SRC FCGR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8756631 17474147
ROCK1 DNM1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31063459 22326220 29654945
GATA3 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21965331 21131965 18162042
EGR1 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17967787 10783396 20018936
FOS SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8917435 11223948 12390531
FOS JUND â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
IGFBP3 IGF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22578544 10407151 11749962
FOS JUNB â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
FOS PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10535756 1331087 1663213
FOS MAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21163924
FOS GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8606973 17895291 12064606
MAF MMP13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20067416
CREB1 NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10435592 11175282
PGR UBE2I â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19211567 17717077 17020914
ESR1 ADCYAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
PRKACA ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17615294
FOSL2 MMP13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10779518 16144844
FOSL2 FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 13679379
GSK3B DNMT3L â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RUNX2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17350616
ESR1 GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15028626 12810571 22962310
ERN1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18471544 27009865
CASP10 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8755496 8962078
FOSL1 IL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22253262 12929935 9488674
FOSL1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20353950 19289495 18288638
PGR PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7113584 8015553 10499541
FOSB IL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21931225 20927330 19665600
MMP1 MMP2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 8194591 7981201 8015608
AKT3 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24379783
RUNX2 DMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12369786 17950631 17434448
GATA3 EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
PGR CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21628418 18483177
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
FOSL2 JUN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CREB5 JUN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
FOSL2 JUNB â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CFLAR FADD â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
FOSL1 JUN â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
FOSL2 JUND â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CREB5 JUND â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
BCAR1 SRC â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
FAS CASP8 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 11717445 5214823
CASP8 FAS â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 5219431 17159907
FAS CASP8 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 16498403 5218359
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
ATF3 JUN â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CASP8 FAS â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
JUNB FOS â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218398 16511568
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
FOXP3 SMAD3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
IL1B IL1R1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
GNAI2 GNAI3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 26186194
JUN JUNB â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 25609649
FOSL2 JUND â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 26496610 12052862 33961781 26186194 20102225 10713367
JUNB FOSB â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 32296183 33961781 12371906
ADCYAP1 GNAS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ADCY9 GNAS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
IFNAR1 IFNAR2 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
JAK1 IRS1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 11162588 7499365 9492017
JUN FOSB â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 29020630 33961781 25609649
CREB1 EP300 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12665587 21268077 10506141 21212407 11313407 7870179 17476304 22787115 26944191 33846793
FAS FADD â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219431 17159907
FAS FADD â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16498403 5218359
ATF3 JUND â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 8152431 30833792 20102225
ATF7 FOS â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 25609649 26186194 15867431 20102225
FOSL2 JUNB â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 32296183 16189514 14499865 26496610 33961781 26186194 20102225 19321746
JUNB FOSL1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32296183 16189514 23661758 24029232 33961781 12371906
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
FADD CFLAR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 22322857 9208847 9228018 9326610 17047155 27321185 21737330 14637155 29497034 33469115 20829884 26972597
SRC BCAR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10739664 10085298 10542110 21034468 17129785 17038317 11514617 10487518 16849545 12972425 12615911 15020686 12397603
FOSL2 JUN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 26496610 9160889 33961781 25609649 26186194 20102225 11708771
ATF3 JUN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 8649793 23661758 26496610 10327051 8622660 1827203 25609649 20102225 14667575 20304822
JUN FOSL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 23661758 11912197 24029232 9160889 20511396 33961781 26258633 11708771 11431474
FOS JUNB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25416956 16511568 23661758 20211142 24029232 26496610 1406655 35140242 20195357 33961781 25609649 26186194 15867431 20102225 10764760
GH1 GHR â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PLAU SERPINE1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
IKBKG IKBKB â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219009 16938294
IKBKB IKBKG â—¼   PHOSPHORYLATION ✅ 0.98 0.98 mint 8209688 16126728 506093200
CASP8 FADD â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 5219431 17159907
BAX BCL2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
JUN MAPK9 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CASP8 CFLAR â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SMAD1 SMURF1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CREB1 CREBBP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
BAX BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21778226 18981409 15899854 32064756 10620799 21199865 17289999 9194558 8358790 21671007 16642033 21458670 22262057 9388232 10716992 20865015 14980220 9111042 24141421 17097560 15231068 9463381 33961781 17525735 29749471 23479509 26004684
FADD CASP8 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21785459 23142077 21988832 23972990 17290218 24098568 14681455 20103630 33469115 18485876 22274400 22864571 25043603 27560715 25939870 29795330 19524512 17159907 30561431 27552911 19176810 15659383 9343261 22179575 22173242 25911380 27321185 8681376 15280356 21737330 26437781 31046799 21458669 12702723 11717445 21737329 19060883 21525013 23429285 20448643 12107169 17047155 9228018 12887920 29497034 12911633 14612908 23955153 33961781 20829884 26972597 21620750
JUND FOS â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 24029232 26496610 35140242 20195357 33961781 25609649 26186194 15867431 20102225 12193410 11431474
CBFB RUNX2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CASP10 FADD â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PKIA PRKACA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IKBKB IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
JUN MAPK8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BCL2 BAX â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
BCL2 BAX â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
MAPK8 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15525785 18471544 16709574
BCL2 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 22705850 18981409 9463381 21458670 17097560 17525735 8358790 10620799 26004684 29749471 9388232 21199865 17525161 22262057 21778226 15486085 17289999 9111042 12419244 9194558 15231068 10716992 8183370 14980220 9115213 21671007 16642033 23479509 10677502
GSK3B BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 29379583 27762303 15525785 20976235 26287183 17911107 16709574
ESR1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19148464 19160418 9306964 11261829 21841772 10542244 20664923 18414489
PGR BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17785366 9306964
CREBBP BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9829964 10753867 17565603 15337521 10454566
MAPK14 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 29050237 16714293 19336399 11495898
MAPK8 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 12421819 26609913 17097560 16738310 21726807 10567572 21993018 29950132 20919655 22848813 15225643 19029119 9738012 18570871 9115213 12039864 11323415 15733859 18471544 15703383 23329792 10677502
AKT3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
BCL2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16183855 11406564
BCL3 IL10 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12907458 14668329 15465827 15749884 16713974 17404308 20547845
BCL3 IL1B â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 12907458 14668329 15465827 15749884 16713974 17404308 20547845
BCL3 IL2 â—¼   DOWN_REGULATES ✅ - 12.0 1.0 ACSN 12907458 14668329 15079071 15465827 15536066 17145890 17404308 19171876 20138012 23430059 8383323 8580069
BCL6 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12097386 11374866 9110977 10490661
BCL6 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23954399 12097386 21801248 21106671 10973278
CREB1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9528858 19882681 18160048 23447579 11704836
BRCA1 CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16940443 19445691 22787115 21087664
BRCA1 FHL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21988832 14550570 25184681 14986435
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
EP300 CDKN2A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
CDKN2A CREBBP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
HRAS CDKN2A â—¼   UP_REGULATES ✅ + 15.0 1.0 ACSN 10358164 12134164 12447393 14764585 16102570 17673906 20841469 24027568 24954210 7510700 7673236 8551221 9069260 9763606 9846483
DMTF1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21892281 10097151 22039255 21062982 15601844 17546045
JUNB CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16966326 19340300 17370299 10856241
TBX3 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18356246 17630961 11748239 18025091 25211658 22039763 15781639 18245468 20624445 17265068 15300007
IKBKB CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21619050 20152798 29292732
NPM1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16957780 20208519 15289458 16199867 16915296
ATF4 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16006626 12082616 10085237 15775988 12083523 16246168 18940792 20020050 17276738 20732869 21044953 22802018 17726049 21966512 17455323 22691366 31226023 24939851
ATF3 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9343434 14729979 22753726 10085237
ATF4 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12805554 20102225 18330356 23661758 16189514
MAPK14 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15187187 19436832 11163539 23331499 15140942 20506250 8650547 21614932 16393692 17570479 11426938 16189514 11274345
MAPK12 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15187187 19436832 15140942 20506250 21614932 16393692 11274345
DDIT3 JUND â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10523647 11426938
EGR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20414733 18798221 15635605 15225550
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
EP300 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11864601
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
CSF2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10426994 11015446 11280761 11460167 11777960 11907067 12193690 12907458 14660645 15536084 16713974 17301840 18264787 20805416 21133840 21232017 21765015 22869907 24030977 24699077 24958845
FADD IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
IL2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10807786 11280761 11460167 14660645 15289500 15563472 17301840 1825141 18264787 18758473 19528259 21133840 21232017 22224781 23650441 24699077 24958845 26755705 2965306 6164929 9625766
IL13 IKBKG â—¼   DOWN_REGULATES ✅ - 20.0 1.0 ACSN 11280761 11460167 12223527 12401408 14610620 14657224 14660645 15099563 17301840 18250477 18264787 18451175 20184663 21097505 21133840 21232017 24699077 24958845 26755705 9535722
VEGFA IKBKG â—¼   DOWN_REGULATES ✅ - 33.0 1.0 ACSN 10022831 11166270 11280761 11460167 11960372 12629515 13678960 14660645 15099563 15111329 15501236 15520864 15573129 16002046 16572188 17086423 17301840 18264787 19414323 21133840 21232017 21372296 22064427 22461508 23390297 24346288 24699077 24958845 26201938 8837607 9157999 9570538 9753319
IKBKG IL6 â—¼   DOWN_REGULATES ✅ - 38.0 1.0 ACSN 10542212 10754326 10952726 11875494 12133805 12907458 14660645 15199157 15465827 15485931 15536066 15644117 15749903 16243976 16413922 16818229 16878026 16970925 17237376 17254973 17363905 17404308 17485448 17693255 18716620 20138012 20300203 21217011 21807870 22435554 23086447 23390297 23422957 23430059 2649237 28462531 7594497 9743347
BIRC2 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19223549 12867425 20301198
IKBKG IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 150.0 1.0 Omnipath 17145710 16938294 20932476 35339487 18266324 16260493 27929056 25979343 19666608 26496610 12133833 12192055 9751060 21423167 19706536 15836773 17561400 22099304 23986494 19959994 15327770 25400026 24266532 18450452 12657630 20434986 11583588 20200955 20300203 21903422 22990857 14743216 20167598 20098747 16126728 19656241 25852190 16906147 10195894 17000764 18329793 16186825 16547522 16611882 18037881 10968790 16497931 25286246 18462684 18207244 16603398 17965022 17977820 24240172 17568778 15084594 16129692 23506214 16319058 23123196 18949366 15218526 22605335 20368414 10837071 19820708 10980203 23131831 17363973 15214841 25304104 16493424 15184390 15691841 11864612 15802604 17693255 21455180 11865184 20211142 11971985 16970925 24469399 24618592 12486103 11057907 24369075 19365808 18583959 27426725 12612076 19422324 10094049 23109003 21803029 12459277 21640763 16285893 18266467 12709429 15620648 17072322 19815509 15749833
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
KAT2B CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9687573 8684459 9687513 9445475 11864601 9267036 17496784
KAT2B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11058129 15994459
MAPK14 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26822034 17726008 21303975 18451303
MAPK14 ZFP36 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25815583 20599781 17570479
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
MAPK14 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14970175
MAPK14 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 10197981 15241418 14512875 16156666 15520018
MAPK14 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11175347 12356771 15733869 11160957 11532940 7958915 9829964 12235136 16189514 11335727 9687510 8887554 11698596 23532963 8688081 9528766 11018520 11969286 11377386 11909979
MAPK14 JUNB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8917518 9889198 20068231 15308641 18669648
MAPK14 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12475989 17689131 17570479 25483191
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
UBE2I TDG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15823533 18691969 21284855 15959518 11889051
UBE2I TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18512959 24753249 18691969
TDG CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11864601 17129768 24748645
GATA3 YY1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
YY1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16784892 17530016 16143308 11418634
SMAD4 COL1A2 â—¼   UP_REGULATES ✅ + 34.0 1.0 ACSN 10964912 11007770 11013220 11074002 11114293 11279127 11283614 11792802 12545156 12702545 12809600 15001984 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9389648 9618481
SMAD3 COL1A2 â—¼   UP_REGULATES ✅ + 34.0 1.0 ACSN 10964912 11007770 11013220 11074002 11114293 11279127 11283614 11792802 12545156 12702545 12809600 15001984 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9389648 9618481
SMAD4 COL1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10797313 11007770 10918613 16319104 9886263 19641518 22048127
SMAD4 COL1A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11074002 9389648 11114293 11013220
SMAD3 COL1A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11074002 9389648 11114293 11013220
COL1A2 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1693626
ATF4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18829529 20824063 14747470 15788408 20221394 24347168 23908598 18172307 18617696 23649506 22915762 18451308
ATF4 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10085237 16246168 21801305 17042743 22819556 23269699 25681212 16989641
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
ATF4 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11564156 9295363 25241761
JUN CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19162185 18024959 18443042 14752027 22674286 23583295 19299558 12667961 10918580 19371341 26554515
FOS CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18024959 18443042 14752027 8063765 12667961 17424890 7602115 9558097 16206198 19404962
JAK1 IL10 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 IL10 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 IL10 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
MAF IL10 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 15749884 16713974 17404308 20547845
CREB1 IL10 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11579131 15187187 15749884 16007092 16713974 17404308 20547845
FOS IL10 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 15067049 15749884 16243976 16327802 16393692 16394015 16413922 16713974 17404308 17485448 19667062 20547845 21372296 21385848 22634314 23390297 23430059 9064320
FOXP3 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20554955 20573297 19775525 24315995 18374871
MAF IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20676095 20676092 19564345 28166218 19414776 15749884 19090621
CREB1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 22140263 26408955 21986577 19564345 12493739 22116830 10540320 18263767 17202341
MMP9 CXCL5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10095777 12950257 16189514
TCL1A AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10983986 11707444
VEGFA CRKL â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
CRKL BCAR1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
VEGFA CRKL â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
CRKL BCAR1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL BCAR1 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
BCAR1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8978305 9498705 18835194 10592173 8810278 10753828 12345678 8943292 23770091
CRKL BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8978305 9498705 18835194 10592173 8810278 10753828 12345678 8943292 23770091
CASP8 FADD â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
FADD CFLAR â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866
FADD CASP8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
FADD FAS â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
FADD CASP8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
FADD FAS â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
FADD CFLAR â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866
FADD CFLAR â—¼   ENZYMATIC_REACTION ✅ 48.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866
CFLAR FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 27321185 12887920 9217161 9326610 21737330 26972597 9228018 17047155 14637155 16189514 20829884 9208847 12220669
FAS FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 22864571 8521815 11717445 21713032 16762833 23606538 8967952 20935634 7538907 21803845 9325248 19118384 12721308 21959933 18328427 16189514 25563855 10196099 17159907 27321185 26186194 25241761 9880544 16498403 21625644 9082980 12107169 15659383 15993755 21382479 7536190 11464215 26942442 11035039 15725726 16410793
FADD CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 82.0 1.0 Omnipath 22864571 17145710 11717445 19524512 34591612 15280356 17047155 27552911 12911633 25043603 21458669 11788820 19176810 21525013 21988832 22179575 25939870 12702723 21737330 21741934 26437781 25911380 9228018 21785459 20829884 23972990 21620750 12220669 9774341 17159907 10521396 27321185 17290218 27560715 20103630 24098568 20203691 14612908 8681377 18485876 12107169 15659383 22421964 20448643 9343261 20125124 8681376 12887920 19060883 21737329 23142077 22173242 26972597 22274400 19935698 16410793
FADD CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 16585540 17145710 15069192 12887920 9045686 11717445 9228018 20829884 15659383
PRKACA CACNA1S â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20937870 2844809 1322891
JUN VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9256279 11204570 11353786 23274526 11678207 17341624 20015448 8910439 16328781 11731421 15039660 19553068 20432243 7887961 12163680 10885623 11281649 14602779 18294451 15277220
SMAD4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23184087 10944227 20797318 12622415 24625091 20631490 18505344
PGR VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9458078 14662796 12568850 15860260 22542550
EGR1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9049304 19526316 20489156 15517885 15737464
ESR1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16267616 12400015 17272396 18252963 18497067 10866309 19420388 19398483 16249470 14647449 15774498 12208749 10995484
SMAD3 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15188178 18952601 20631490 22740248 21057546 15629128 11486006 15191565
GNAS ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9228084 9395396 1719547 9268375 21406690
GNAS ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9228084 6935665 210183 17652154 2022671 21406690 32196115
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 HMGA2 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 9389648
SMAD4 ATF3 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
SMAD4 SMAD3 â—¼   PROTEIN_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 ATF3 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
SMAD4 HMGA2 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 9389648
SMAD4 POSTN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11074002 11279127 11792802 12702545 12809600 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9389648 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 ATF3 â—¼   UP_REGULATES ✅ + 36.0 1.0 ACSN 11074002 11170475 11279127 11792802 12490555 12702545 12718878 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 23850759 8893010 9389648 9865696
SMAD4 APOC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10995777 11229886 16771709
SMAD4 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9792626 19752858 9765209 12551947 10636910 10092624 9606191
UBE2I SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 21988832 31515488 16189514 15637079 16713569 12621041 29892012 15231748
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
SMAD4 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9732876 10942775
IL1B IL1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17145710 23331499 8142597 9062193 7878046 9820540 7775431 2946959 24166242 9625767
IFNAR1 JAK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15312780 8943354 18508557 15449939 17969444 16171819
IL9 JAK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 25297818 15143194 1376929 7718508 21439476
CSF3 JAK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8197119 16492764 16720384 7512720 10537111
JAK1 PLAU â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
JAK1 IL13 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10485906 11867689 12223527 12401408 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 7512720 7521688 7543512 9535722
JAK1 IFNAR1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
JAK1 IL4 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21115385 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
JAK1 IFNGR2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IL6 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK1 IFNAR2 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
JAK1 IL2 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IFNAR1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
JAK1 IFNAR2 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
JAK1 IL6 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK1 IL2 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
JAK1 IL4 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21115385 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
JAK1 IL13 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10485906 11867689 12223527 12401408 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 7512720 7521688 7543512 9535722
JAK1 IFNGR2 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 PLAU â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
JAK1 IL6 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK1 IRS2 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
JAK1 IL4 â—¼   ENZYMATIC_REACTION ✅ 34.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21115385 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
IFNAR2 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9334213 23331499 7988557 12133952 23180781 16710296 18988627
IFNAR1 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 8943354 18508557 8232552 17351669 8524272 7526154 9334213 23331499 10542297 11694501 10982844 15449939 15312780 8702790 8621447 17969444 8605876 10022928 15120645 16171819 29145629 8197134 16987978 24243840
JAK1 IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11591769 9233603 7499365
JAK1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15001544 11591769 8756628 7544789 9305869 11162588 9233603 15592455 7499365 12220227
SERPINE1 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22449964 2544876 2161846 21199867 3090045 9184208
SMAD3 POSTN â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD3 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11278818 11331591
SMAD3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14754879 12672795 18804287 12853969
SMAD3 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19643931 15840021 19563779 12551947 24330518 9792626 19132220 19887897 11590145 9765209 19586629 18333754 16169848 15561701 10092624 10557285 20093492 11387330 9606191 17761371 23063463 15198928 9380693
SMAD3 EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17376964 22301113 16740983 15838328
SMAD3 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26365427 22908322 25065622 18157133 23243069 20937549 19701891
GSK3B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 18172167 21071413 21310903 23077590 28756206 19114991 19002158
CREBBP SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15849193 10497242 15467747 18003620 9679056 15990875 15750622 19589780 17074756 17283070 9679060
SMURF1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10458166 23331499 15221015 15761153 15231748
MAPK8 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10601313 25714018
SMAD3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9732876 10220381 11306568 21829441 10903323
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
SMAD3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21986102 10962029 15084595 11331591 10531362
IRF1 MMP9 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10485906 10820262 11399519 11875494 12417340 12433365 15644117 16127449 16597464 17260466 17689680 18345002 21097505 22461508 23390297 6357187 8871614
FOS MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16554298 11774399 21238464 18809380 23508111 21474819 15319566 10935492 21940623 24173318 16882662 21047770 9136992 23955082 23176293 12032150
FOSL1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16554298 22514284 22514348 15319566 17572495
JUN MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 16798740 16554298 11774399 15949416 11429784 15777790 16014933 10935492 11326313 18809380 21474819 21963718 19455716 9136992 17572495 23176293 15708369
CREB1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11413310 12388374 7513046
JUND CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10760799 19828633
JUN CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11413310 10760799 19828633 10075858 20862675 26096887 7513046
IRF1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10385645 11413310 22292067 17565659 10713367 20861350 15860458 16707500 12388374 12165487 10926836
ATF3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20203264 24317040 17785797 24951825 20351107 22105779 16688168 18942706 17766920
JUND IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10037779 11337499 11886848 12727841 24676671
FOS IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10037779 10542237 9671466 2511437 25567680 20351184 24994901 11356008 11028561 12667961 18502099
JUN IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 26513016 10542237 21069809 15389813 15158360 20225236 12667961 20371366 20511231 20862675 8453101 10202034 18502099 10037779 8830832 19687301 21098092 25567680 20351184 17341596 11120852 21312239 24676671
EGR1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18281687 24453276 23632636 15517885 23184950
IRF1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 7509445 7499267 24012417 9394833 26206900
CREB1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8725624 19342597 20100571 20160059 11701462 16424113 18617614 19162127 15467434 21209948 23874122 17495236
JUNB IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20221401 11337499 12070012 7836389 10497240 19918056 8537375
NF1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8628317 19777070 26635368 24431436 19718661
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
HRAS MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11525649 8137421 16810318 16713569
SRC BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 19901323 24962474 11514617 8670206 15316024 20927395 8070403 17389395 12480533 22710723 30422386 25976166 17570479 21963850 12972425 20103658 17129785 10487518 15817476 21301050 10739664 17038317 21765460 17016520 12397603 15212693 15020686 10542110 23457577 10085298 12615911 15272013 21034468 11604500
SMURF1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 14701756 17676934 15221015 19914168 21708152 22298955 24828823 19917253 16611643 17510966 15761153 22670624 22152476 17289590 15231748 21685363 27447855
SMURF1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17145710 14701828 16299379 12738770
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN IRS2 â—¼   ENZYMATIC_REACTION ✅ 37.0 1.0 ACSN 11274345 11955436 11967263 12051714 12417340 15001769 15279786 15337521 16007092 16039586 16510874 17143292 17303408 17439715 17565603 17660363 17936032 18590585 19619488 19623618 19879327 20006983 20144767 20530697 20705860 20920541 21285352 22020335 23296977 23343194 24023259 25730849 26587781 7542250 7575488 8545107 8666229
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
JUN IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15187114 15270850 14688340 25567680 11279072
JUN IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15586248 22649503 16374477 15790882 9424084 9506439 17882273 15025563 7759510 20006635 17205062 21966511 15037572
JUN CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9190901 12760745 19890352 1900839 8135780 11509589 8524292 7579683 10330159 9862439 15840658
JUN ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8576171 21304988 14667575 10979959 22870894
JUN IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11306276 18566416 7935377 10226077 14686613 16365456 11145674 17283046 20463008 23608488 8133045 8798756 18789903 16729332
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
JUN NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11382920 17933457 20371606 16453281 18556800 17919072
JUN GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8606973 16978907 12064606 15618352 10421804
JUN EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740983 1918021 22301113 21239258 12208352 21216243
JUN DCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 7499226 8798756 8940199
JUN MMP13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 9119388 19783677 21461405 11641401 10779518 17905570 14686613 19038372 17626252 10911363 8957070 15994313 9989817 9334186 9212062 12032154 9138284 17822788 14575638 15084595 22158614 11691923 16023836 11852231 12460732 15063796 19126648 11274169 20067416 22128168 11689447 16919424 20338993 10891395 10830307
JUN CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9486962 23385061 15574764 17182846 15737994 21069729 9511728 20531301 21029732
JUN PENK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7477937 2512642 1491720 7935470 8931456 9147818 8632147
JUN IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8996240 10772943 9889198 9133600 21989417 9310836 15546613 21454593 12594266
JUN NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11905996 11733514 8717334 2111020
JUN SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11440364 12390531 19887897 19288028 15069077 22926518 10591684 11223948 12905745 14592829 16105028 17890327 21969564 8917435 8342330 19088796 20351105
JUN MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 22437631 10913304 20463008 20225236 10206959 16707434 20648623 9178763 15027120 19708869 10914841 15090544 14550555 9923649 11156425 9334186 8798622 16317516 19028685 11259586 16380175 12871225 15467742 10995748 21640141 16569638
JUN IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 20557936 12370343 10700231 12884855 8436291 9541574 8397339 1737937 9605137 8683110 21832163 9590239 7989759 9774418 16116194 8473495 8114694 10878360 10320367 9233628 7642615 17097050 7565732 8468462 8660843 7739550 8051409 1740667 19181930
JUN CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19022561 16810058 21393445 15688015
JUN FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18435914 15806162 13679379 17082637
JUN SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7499226 16798740 23533633 14736735 18216279
JUN MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19268464 15212943 14767528 19940138 11414701 15777790 20353950 17116726 16000878
JUN BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9257196 2124710 15831452 17308994
JUN FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733515 12963547 10903433 19670268
JUN MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9334186 15777790 23608488 8957070 1429874 14755151
GSK3B JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 23331499 1846781 25979842 25241761 20537194 21278055 21397588 17482134 1516134 8384355 17570479 16023596 17215518 30086763 92065884 24632621
MAPK9 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 17143273 17145710 17637567 12584171 20506250 11948398 15378002 16824735 9687508 8654373 20028971 12788955 9305638 15302935 26091349 33822843 18362184 17875713 16393692 9405416 17570479 1922387 18252863 25561726 7737130 10490605 17189706 11896587 34408980 11274345 20178741 8525045 16076903 7992057 19527717 7600582 17215518 8985011 11801649 19118012 11278395 8001819 8137421 19436832 16533805 8945519 12881422 9315636 10385525 12093796 14523011 19910486 15212693 8157646 12040039 11562357
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
RUNX2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11641401 11274169
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
UBE2I JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11877416 16713569 16055711 10788439 8733011
ATF3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10327051 25609649 1827203 14667575 20102225 23661758 8622660 20304822 8649793
CREBBP JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8028671 10327051 2138276 9659924 9786917 16713569 17296604 8545107 18443043 16055710
MAPK8 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 202.0 1.0 Omnipath 17143273 17804415 10617656 8846788 15958389 11948398 10882101 20028971 12697749 15894542 20514406 14612408 17875713 9891069 17570479 18922473 11809792 8586671 11896587 12185592 12871843 7992057 7600582 11278395 8137421 8001819 10493750 14557262 16549498 18707149 9169478 11460167 15289320 8157646 16007099 20506250 22110360 15378002 9687508 12740383 20732415 9305638 19270716 23331499 10747973 16291755 16393692 12832416 18988627 10713700 18669648 12087092 14633987 8525045 15677475 16076903 16166642 18650425 15590691 1608942 19910486 18212344 11562357 12228228 16740711 14701799 19690332 10871633 12531896 16713569 8654373 16983342 19664995 15302935 10962563 15068801 8621542 8607977 18362184 10393177 20068231 9808624 14572659 8224842 10585392 9407028 17363973 19527717 19436832 14517282 12407442 9487126 9692890 14523011 15212693 10908726 11108663 13130464 10064600 18429822 15299005 9774977 11907583 12963725 16824735 19413330 10617104 17055484 21071413 18452278 16434970 16157600 7737130 23816567 10987838 17189706 9561845 9575168 1460037 7652575 18617513 24113186 11971971 11801649 25098452 20058876 16533805 9184210 18003900 9315636 10385525 18957422 12881422 11274345 12052834 15749833
JUN FOSL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25609649 26186194 9160889 11708771 20102225 26496610 32296183
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
JUN ATF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10327051 25609649 1827203 14667575 20102225 23661758 8622660 20304822 8649793
JUN FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9160889 11708771 23661758 20511396 11431474 24029232 11912197
CFLAR FAS â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866
CFLAR FAS â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866
CFLAR FAS â—¼   ENZYMATIC_REACTION ✅ 48.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866
EGR1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9300687 12556466 15155664 14751836 10508276
ITCH CFLAR â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157 26972597
ITCH CFLAR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 30736843 16469705 19090833 18786561
CFLAR CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 23541952 12887920 25241761 9289491 21737330 9228018 9208847
CFLAR CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 22864571 17145710 19416807 9217161 9326610 11741985 15280356 14585074 17047155 9794838 9208847 24438025 9289491 19710364 21737330 19343040 9228018 17159907 26186194 9380701 9880531 22421964 21737329 12887920 12215447 12097160 15024054
NGF IRS1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 15099563 16931767 17604717 17764704 19030972 21540285 22421439 22465479 24036369 25071162 28645028 8621421
NGF IRS1 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 15099563 16931767 17604717 17764704 19030972 21540285 22421439 22465479 24036369 25071162 28645028 8621421
FOS NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8473354 2111020 2849107 9221899 8717334
IRF1 CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17036321 14993214 22427665 23255602
IRF1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14993214 19129219
SRC CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 27432652 16619028 19470771 27109099 27195913 19383910 30501030 24100030 22074016
CASP8 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18073771 9545235 10872455 18329793 9727491 9463409
CASP8 CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 22864571 17159907 17145710 12887920 11832478 11717445 21737330 15280356 12198154 3031469 15659383 170210 8962078 22421964
SRC CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 12707358
CHUK IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 16510874 23343194 21285352 22020335 23296977 11274345 16039586 17439715 20920541 20530697 15337521 8545107 19619488 19623618 17565603 17143292 20006983
CHUK CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21674813 17145710 14597638 17434128 22435559 12789342 27220480
CHUK IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 9346484 24911653 20932476 28514442 11971985 16970925 12210728 9346485 17965022 16713569 12486103 9891086 15456791 11057907 20434986 16129692 16260493 21903422 21724995 16286467 14743216 16319058 18949366 10779355 25748427 25852190 12244103 11585904 9751060 15218526 10094049 10837071 9914500 21575199 9721103 25241761 10195894 9689078 15214841 21784860 17561400 21640763 16285893 10733566 16186825 16493424 10022904 12709429 12351658 10968790 12547194 15691841 15620648 15327770 11864612 11460167 14636585 17693255 17072322 9346241
IFNAR2 IFNAR1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
IFNAR2 IFNAR1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
IFNA13 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 8181059 10395669 11278538 11698684 21856167
IRF9 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17923090 18456457
CREB1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11313407 12370343 17548609 12626549 15993752 12432566 8670878 8814256 11238674
FOXP3 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 25567984 23275607 22806628 21458306 17028180 16873067 21955384 17586580 23954131 17922010 20429413 18324310 19172156 17416586 22579476 18779564 17430097 21654845 17632414 11483607 18759924 19564342
EGR1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19915002 10656874 12560487 9756940 7673240 20680391 8773576 17142725
FOS IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20557936 8893011 11260070 11685114 8397339 1737937 9605137 9590239 11262396 7989759 1916630 8473495 10601992 8114694 22474330 18725523 9233628 11385624 2518655 15170389 8468462 7565732 12432566 8660843 7739550 1305903 20680391 19181930
CREB1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 10866654 18599546 15585582 7870178 8028671 11313407 16007092 8413673 11564156 15691881 9829964 15073328 20403362 11259575 17476304 17707401 20541704 16799563 7870179 11123304 27789289 7913207 12933667 8663317 8004670 11483993 12198160 9413984
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
IL4 MAF â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
IL4 IRS2 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL4 IL13 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
IL4 CSF1R â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 2965306 9834059
MAF IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 14688382 19553542 17057718 26278622 9889198 24821970 17507085 9442389 11956291 15832295 15495158 9815263 9686601 18167455 25037220 22798672 19348920 8674125 15728480 16498264
GATA3 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 22226971 21536806 19881507 11093124 20636338 15941711 9846495 22039304 17277157 11893731 16266280 12876556 9442389 11336690 15832295 23232398 17658278 26840450 18167455 25037220 9780145 25861992 21989417 21131966 9780146 16498264 10894164
FOXP3 IL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20554955 20573297 18395799 19775525 18374871
IL13 IRS2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 12223527 12401408 14610620 14657224 15099563 18250477 18451175 20184663 21097505 26755705 9535722
GATA3 IL13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18056374 22226971 21536806 16009272 24167278 25148023 11591766 20636338 22039304 17277157 11893731 26227022 20368097 23232398 12947222 23796028 15494506 25861992 15826950 21989417 18028994
IRF1 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16253303 19342664 19880820 17167270 24130180 19929594 9858321 24127910 27551049 19541350 9794404
FOS CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9190901 1900839 8135780 11509589 9028942 12432566 7579683 8631792 9862439
GZMB CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19103589 17283187 15569669 15650747 8631895 21042704
GNAI2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 11007482 11160627 10753828 9722546
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
SRC ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10330414 17473008 8631894 18156175 25694433 18840695 18364349 18398066 10592173 16935858 21956114 17353363 18088087 12359711 15212693 14996908 15695822 15699036 11723131 20702409
SRC CYP19A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 31652308 19556341
SRC IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 12645577 12707358 15456896
SRC GJA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 24508467 19901323 16492141 21856279 10871288 11514593 10679481 15782139 9592087 16189514 30448479 30095367 19284610 26706150 30323740 27280719 9278444 24670366 15350848 16916748 23718910 22342665 15534005 29587860 23596415
SRC FCGR2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8756631 17474147 18083107
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
ROCK1 SOX9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21818404 11120880 32277958 27128146 20039424
ROCK1 MYL9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8702756 21457715
CREB1 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18471910 20136501 17721610
ESR1 JUND â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 25542856 18219272 3677090 20219941 23145106 1630819 3045126 15514030 24854081 22265404 17013392 21835891 9671459 21940756
JUND FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23319049 13679379
JUND IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11254751 17882273 7759510 17205062 10816578
JUND MMP13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10779518 16144844 14686613
JUND IL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24036113 7806493 19665600 21931225 20927330 12929935 9488674
MAPK8 JUND â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16007120 22327296 14676207 12052834 26538579
EGR1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18044710 17631285 7823937 12734378 22455954 15569263 8709978 16601242 12637574 10202038
EGR1 IGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14517213 9610618 11336542 8634146 10606246 8276819
EGR1 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17764926 21205742 16079301 16489044 18719024
FOS IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7679081 20463008 7935377 14686613
IRF1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11359842 19843519 9754830 20617571 19929594 12759449 26206900
PRKACA IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17360977 12624099
MAPK9 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11160134 9335553 12417588 14579029
IKBKB IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 10722755 19651622 24337154 18443205 23050932 15199052 20953398 25381390 16129690 29767231 11606564 18077418 14583092 15613682 16099428 12351658
MAPK8 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15001544 18728222 26882989 12409308 10592173 15314024 12417588 15613682 14579029 10722755 26538579 29207597 15199052 12351658 16055440 11606564 12510059 15212693
IGF2 IGFALS â—¼   PHYSICAL_INTERACTION 22.0 1.0 Reactome 11788658 11316783 7689487 15469690 9497324 10026136 12379487 7543116 17047378 10681634 11250653 7683646 10810289 1370451 12466191 15126567 9709957 7519608 2476804 15485880 12810533 8781553
IGF2 MMP1 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
IGF2 MMP2 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
IGFBP3 IGFALS â—¼   PHYSICAL_INTERACTION 22.0 1.0 Reactome 11788658 11316783 7689487 15469690 9497324 10026136 12379487 7543116 17047378 10681634 11250653 7683646 10810289 1370451 12466191 15126567 9709957 7519608 2476804 15485880 12810533 8781553
MMP1 IGFBP3 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
MMP2 IGFBP3 â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
JUNB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1380150 2116003 8934539 11698415 9813041
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
FOS PENK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1828294 7894225 7477937 2512642 9147818 7568884 8632147 8346209
FOS MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11665970 19028685 9334186 16380175 10914841 15090544 20463008 15467742 10684971
FOS MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9334186 20609072 23608488 8957070 8921230
FOS NPPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19538471 7721415 1530876 8417355 9403552
FOS IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19285436 15187114 15270850 14688340 25567680
FOS FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8446579 13679379 17371847 15514944
FOS BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9610372 10804019 2124710 8828501 1749528
FOS PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16293641 14684847 12446585
PRKACA FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9920881 20068231 18452278 8248197 1545828
HMGA2 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17324944 21566082 17005673 14645522
ATF3 IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17785797 16688168 24317040 26416280
MAPK8 ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23435430 16469705 15358865 16446428
BIRC2 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16339151 9384571 16189514 11084335
IRF1 IL27 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24214980 20083668 17548596 17684041 26900987 17227910 20435892 17985330
IRF1 IFNA13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 14581002 1371248 9078371 10358173 17617740 12466898 23670564 23542606 12077266 11473119 17785777 8062214 8621447 7507207 8052267 1712401 7559730 19929594 9315689 10406469 8805641 10321737 7957048 7687740 2911367 1614874 9625761 27012395 9831185 2475256 8004672 15722233 7606736
IRF1 IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12417340 17924060 10657616 24012417 10861061 12517966 17635610
IRF1 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11694349 9492014 8015552 12017556
CREB1 PRKACA â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 19244110 12150772 12082174 2573431 9733829 17908236 15879576
CREB1 CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15955695 23846817 21212407 17596931 9365194 19679653 12846424 16740737 23566437 11850205
CREB1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11160720 20857405 8641461 17325033 12869629 19343785
CREB1 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17599098 19712055 25031400 11719924 21335064 32603820 14735135 11377882 19046370 22179316 21677163 17456785 23946409 17164818 9581764 18063565 9581763 16337876 20100784
AKT3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
GSK3B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16568235 12162494
PRKACA CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11175347 12356771 15733869 11160957 21902831 2885756 2875459 7958915 9829964 12235136 12763014 9687510 8887554 15568017 11698596 8688081 9528766 11018520 11969286 11909979 8336722
IFNA13 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 7932753 23331499 8181059 11698684 21856167
GSK3B SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 18045539 25241761
PRKACA SOX9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 27929080 19470758 10805756 15889150
GNAI2 ADCY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 2121366 8327893 19703466
AKT3 CREB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
AKT3 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20016067 17680028 20214616 17688959 20398329 16537363 17052453 19575820
PKIA PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1770951 8027074 7905001
PRKACA MAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12369833 2561875 8391085 33526823 11029056
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
PRKACA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15319357 12522122 34204249 10376603 31923467 16839566 33429979 34026871 16946136 10908731 10671564 16270749 11729179 12171920 26132171 11978735 17572401 24379783 10376602 16873402
PRKACA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16543730 15845746 18691976 19836308 8524413 12054501 16039586 12147701 16522636 11035810 18669648
PRKACA ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 2847175 1847804 8132598 19144319 12529267 14741364
FOSL2 IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10816578 11254751
AKT3 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 12851486 15023346 21303971 11882383 17680028 9065430 23109003 20214616 22094462 23552696 20398329 21506126 20028971 12040186 18218901
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
ESR1 FOSB â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 25542856 18219272 3677090 20219941 23145106 1630819 3045126 15514030 24854081 22265404 17013392 21835891 9671459 21940756
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
ESR1 MMP13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19185056 18358246 16919424
ESR1 FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22514284 20034404
ESR1 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 3481434 9259323 7649480 18022314 2082192 10830306
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
ESR1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22052999 11029009 10690351 14742696 19914929
ESR1 CYP19A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19462000 20351196 19605792 11973645 16885386 19282383 19250199 12839940
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
MAPK8 APLP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15212693 14970211 9109675
MAPK8 JUNB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8917518 18669648 9889198 20068231 9405416
FOSL1 MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22437631 18802113 25339983 10913304 14519134 21640141
FOSL1 IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15790882 11254751 17882273 7759510 17205062 10816578
BIRC3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16339151 9384571
IRF9 IFNA13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20403236 9186002 22252317 15145216 22626811 8864350
JUNB MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19944019 16699069 19289495
MMP2 IGFALS â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
MMP1 IGFALS â—¼   CLEAVAGE ✅ 6.0 1.0 Reactome 8817670 9922210 7523391 12379487 12466191 17047378
AKT3 TBX3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25595898
GH2 GHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 2387255 1955498
GH1 GHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 2825030 8943276 17500058 1549776 9353194 26713839 1935820 31279174 9030599 23331499 7862673 7691587 19927328 10551877 21889455 9571026 3349036 2387255 31100495 29145629 24280222 24243840
RUNX2 MMP13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10330183 16144844 21461405 11641401 10671545 15084595 16636074 16166639 19121369 10891395 19423655 14982932 11691923 15564063 22095691 19649655 20870727
JUNB IVL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7759510 17882273 21966511 15790882
DMTF1 DMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16878159 17196192 22549196 16679514 21062982 15601844 15108359
GHRH GHRHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 1333056 26917260 7680413 76804131333056