PKG

Protein list:

RUNX2 BMP2 KLK3 AKR1B1 MAPK1 LGALS3 HDAC7 BGLAP NELL1 HES1 FHL2 FGFR2 IGF1 COL10A1 VEGFC GAS7 SNAI3 ELANE MAPK11 GGCX MMP2 TGFB1 MAPK14 SNAI2 COL1A2 FGF2 CTNNB1 VEGFA TWIST1 TWIST2 EP300 HDAC5 SP7 TP73 CDK1 SMURF1 HDAC4 MAPK3 CREBBP MYC BIRC5 SMAD4 FGF10 LYPD3 NOTCH1 ALYREF POC5 JUN KISS1R GLI1 LEF1 GNAS FOSL1 FBXW7 BHLHE40 RBM14 MSX2 ETS1 CBFB CUL4A PML AMBN INS STUB1 HIVEP3 LPAR4 CCN2 NMES1 DCAF4 CSN2 DDX5 FSHB GFI1 SOX9 KAT6B RYBP CUL1 CDKN1B WWTR1 SMAD6 HEY1 KLF10 USF1 TP53 PIN1 TERT FOS SATB2 HEY2 PRKN SMAD2 CUL4B RB1 WWP1 PTTG1IP AR CTBP2 MAF SDC1 DHCR7 BMPR1A WWP2 ZNF384 ID1 SDC3 CUX1 TCF7L2 STAT5A SOX6 NEDD4 SOX5 ZBTB32 RBX1 SOST KAT2B ODAM KAT6A CLC ARID4A SUV39H1 GLI2 GPER1 HDAC6 THBS1 USF2 SKP1 RUNX1 XRCC5 HDAC1 NR3C1 AP2B1 EPAS1 TBX3 XRCC6 GPC1 HNF1A SKP2 RUNX3 SMAD5 FOXO3 YAP1 JUNB GLIS3 HAND2 PAX5 FGF3 SOX2 ATF4 TLE1 SDC4 NR0B2 TIMP1 CYP51A1 CSF1R CSF2 SMAD3 GJA1 STAT1 TRAM2 HIF1A BAX SDC2 DLX3 CEBPA TNFAIP6 TSHR FGF18 AKT1 ABCB1 HAPLN1 UBTF VCAN OSR2 SHH KLK4 IL1B GNA13 MPO SNAI1 OSR1 FGFR3 ATF6 SMURF2 ADGRG2 CDK4 HBEGF PTTG1 ZNF521 PTCH1 PBX1 HPSE RARA ESRRA SLPI STAT3 MMP14 GLI3 TAFAZZIN CCNE1 GSK3B NEU2 ZFP64 SMPD3 NR2F2 GDF10 CYP11A1 IL11 MEF2C

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Protein:

Eg: PBRM1 | ARID1A | BRCA1

Function:

Eg: Homologous recombination

Path:

Eg: SMC5 > DMC1 | PBRM1 > BRCA2

Relationship:

Full list of relationships

Graph tools:

Note this may take some time with > 30 proteins

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PKG Score Threshold: 0.8

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Source	Target	Relationship Type	Directed	Sign	DB Score	PKG Score	Database	References
AKT1	CDKN1B	◼ ENZYMATIC_REACTION	✅		2.0	0.8	Reactome	12244303 11231573
AKT1	MYC	◼ POST_TRANSLATIONAL_REGULATION	✅	-	2.0	0.8	Omnipath	17942906 9804616
AKT1	SP7	◼ POST_TRANSLATIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	21619873 21777568
AKT1	GSK3B	◼ DOWN_REGULATES	✅	-	0.82	0.82	Signor	15829723
AKT1	GSK3B	◼ PHOSPHORYLATION	✅	-	0.82	0.82	Signor	23552696
AKT1	MAPK14	◼ PHYSICAL_INTERACTION			830.0	0.83	STRING	36370105
AKT1	SKP2	◼ PHYSICAL_INTERACTION			839.0	0.83	STRING	36370105
AKT1	CDKN1B	◼ TRANSCRIPTIONAL_REGULATION	✅	-	0.84	0.84	Signor	18423396
AKT1	SMAD2	◼ PHYSICAL_INTERACTION			0.86	0.86	HIPPIE	24412244 16362038
AKT1	AR	◼ PHYSICAL_INTERACTION			870.0	0.87	STRING	36370105

Showing 1 to 10 of 1,435 entries