PKG

Protein list:

STAT3 LBP CPT1A MMP9 CCND3 PXN CPT1B IL17F GALNS GRB2 CCND2 TIMP1 IL27 NTF4 TICAM1 PGF A2M CPT1C ADIPOQ PRKD1 AKT1 CEBPD VEGFD BCL6 FGG CD46 PTGIR NF2 IL2 CISH IL2RG IL12RB2 PIM2 IL11 PIAS2 IL23A EPOR GH1 IL12RB1 PDGFB PIK3CA RACGAP1 NTF3 SOCS3 VEGFC CRP VEGFB IRF1 MUC1 GLB1 SOCS1 IL1B PPARGC1A HGF HGS HAT1 IL12A NTRK3 CXCL12 PIAS1 NTRK2 EBI3 PRKCQ IL12B PIAS4 KIT NTRK1 IL18 CSF3 PDGFA IL17A NANOG KAT7 ETV6 THPO PDGFD NOP2 IL22RA1 GAB2 IL10RA MPL LRPPRC IL20RB RASA1 IL27RA FLT3 SOCS5 CXCL8 SOCS2 SOCS4 PLA2G4A HSP90B1 PTPRR RET/PTC2 STC2 PTPRG MFGE8 MAP3K1 CNTFR PPP1CA PPARG NLK CDK5 PRKCE RPS6KA5 PKM FGFR4 PTPN6 PHB1 MAPK9 IL1RN PTPRT PTPRD IRAK1 MAPK8 SALL4 FOXP3 IL20RA IL21R MAPK14 PRKCD RORC TGFB1 HCK PTPN1 FGFR3 TYK2 STAT1 SP1 MAPK3 SMAD1 OGDHL PARK2 ZDHHC5 RBM8A CBFA2T2 BCKDK CBL ZFHX3 IL10 KDM1A AMBP NFE2L2 MAGEC2 HSPB1 BICD1 CORO1A PTK2 CAPNS1 SLC25A36 IL7R HNF1A STAT2 SULT2A1 SOCS7 CHTF18 SPRY1 FZD2 USP28 GHR SH2B1 PGR LYN RFWD2 HIF1AN ZRANB1 GSTCD TRIM28 TWIST1 MAP3K7 HIVEP1 IL23R VHL VIF CAPN1 CDK9 ZNF281 OFCC1 LEPR ZFPM2 CEP70 GAS5 TXN TSHR MAPK13 CA9 CRTC2 RB1CC1 KRTAP10-7 RPS9 FGFR1 NFKB2 FGFR2 MNDA BCL3 SMARCA4 TASOR2 WDFY3 MEG3 RABGAP1 OCIAD1 CD44 GTF2I MDM2 HESX1 RRAD GSDMB PGK1 PRDX2 FYN DUT LAMB2 LMO2 CREB1 GH2 ELP2 IL6R GNB2 RPA2 APEX1 IFNAR1 MRPS31 TIRAP CEP120 GNL3 RPS6KA1 JAK3 PTCH1 STAT6 SIAH2 STK4 HSCB SIN3A

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Protein:

Eg: PBRM1 | ARID1A | BRCA1

Function:

Eg: Homologous recombination

Path:

Eg: SMC5 > DMC1 | PBRM1 > BRCA2

Relationship:

Full list of relationships

Graph tools:

Note this may take some time with > 30 proteins

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PKG Score Threshold: 0.8

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Source	Target	Relationship Type	Directed	DB Score	PKG Score	Database	References
A2M	KRTAP10-7	◼ PHYSICAL_INTERACTION		2.0	0.8	intact	108050 32814053
A2M	MNDA	◼ PHYSICAL_INTERACTION		2.0	0.8	intact	108050 32814053
A2M	LYN	◼ PHYSICAL_INTERACTION		2.0	0.8	intact	108050 32814053
AKT1	MDM2	◼ PHOSPHORYLATION	✅	0.81	0.81	mint	5217292 15527798
AKT1	MAPK14	◼ PHYSICAL_INTERACTION		830.0	0.83	STRING	36370105
AKT1	PIK3CA	◼ PHYSICAL_INTERACTION		880.0	0.88	STRING	36370105
AKT1	MDM2	◼ PHYSICAL_INTERACTION		899.0	0.89	STRING	36370105
AKT1	STK4	◼ PHYSICAL_INTERACTION		0.94	0.94	HIPPIE	19940129 17932490
AKT1	MDM2	◼ ENZYMATIC_REACTION	✅	7.0	1.0	ACSN	11154281 11715018 11923280 15169778 17680028 20214616 20398329
AKT1	MMP9	◼ ENZYMATIC_REACTION	✅	20.0	1.0	ACSN	17409395 17680028 18471976 19440036 19930715 19945467 20214616 20398329 20609352 21084277 22131018 23572150 23589069 24030100 25136802 26597054 27328425 27510662 27572739 29556339

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