Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AR PIGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11171058
RPS4X SRP54 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RPS18 SRP54 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 MTA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23552838 22286760
H1-2 FOXO4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PARP1 H1-2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18250087
THAP12 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12384512 16189514
ABL1 CKAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CUL7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 UHMK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
FOXO3 AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10102273 5211323
PHLPP1 AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17386267 15808505
AKT1 PHLPP2 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17386267 15808505
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
MAPK8 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16306447
SIRT1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21775285
AKT1 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20605787
CASP3 AKT2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
ILK AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11507039 19460343
AKT3 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
TRAF6 AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19713527
ALB YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR LATS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15131260 20610535
AR SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18829485
AR PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 20610535
AR NF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16046619
AR HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 21125667
PRDX1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17909037 19737972
DDX5 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18829551
AR FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18391971
PARP1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16647857
FOXO3 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20211690 19807657
FOXO1 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19050291 15565601
PARP1 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 7596430 376037
CASP3 STK4 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 9545236 11278283
CASP3 PTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12004072
YWHAG CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
FYN CBL â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL FYN â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
STRN4 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MOB4 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT3 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CCT3 STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 24756126 1001844
CCT3 RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216198 12620389
STRN3 CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MOB4 CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT7 PER1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STRN3 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MOB4 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
FYN CKAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
XRCC6 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
SMAD4 CNKSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MDFI CRY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PER1 CRY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10790862 11165242
CSE1L YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SIRT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27776347 28583374
PPP2CA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10644691 19061640
PPP2CA CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CTTNBP2NL STRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23015759 18782753
RASSF1 DAXX â—¼   COLOCALIZATION 2.0 0.8 intact 18566590 6799761
DAXX TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 14557665 5216762
EIF4B DDX3X â—¼   COLOCALIZATION 2.0 0.8 intact 8407815 22872150
DLG5 GTF2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSP90AA1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
DNAJA1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EEF1A2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STAT1 EGLN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17558387 19574556
YWHAG ERC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
FBXW11 PER1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15917223 15917222
STRIP1 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MOB4 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
NCL FOXO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FOXO1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21149440 23430617
FOXO1 SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17408630 18420577
FOXO1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25510553 19049975
FOXO3 SIRT1 â—¼   DEACETYLATION ✅ 2.0 0.8 Reactome 14976264 23665396
FOXO4 SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536589
STK4 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21106439 18394876
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GAPDH LAMTOR5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GAPDH PRDX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HDAC6 TUBA4A â—¼   COLOCALIZATION 2.0 0.8 intact 5215415 12024216
HDAC6 TUBA4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12024216
SMAD4 HDLBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 HSPA1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA1L TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NEUROD1 HSPA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA2 PER1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA5 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPA8 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19229036 23349863
HSPA9 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA9 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TP53 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPB1 PER1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 TUBB6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IL2RG STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11418623
IPO7 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KPNB1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MOB1B LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
MOB1A LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
TP53 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17015431
MOB1A LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
MOB1B LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084559 19739119
NCL LTF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21575138 8175189
MAP1LC3A SQSTM1 â—¼   COLOCALIZATION 2.0 0.8 intact 19427866 7034152
SQSTM1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAP1LC3B SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18296641 0712145105
STK4 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9182538
TP53 MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15899946
YWHAB MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
MDM4 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 19521340 7290688
MOB1B MST1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219739 17347649
STRN4 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TP53 MSH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12209975
SPTAN1 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22103682 8291914
YWHAG PABPC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PARP1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PCBP2 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PTBP1 PCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PHLPP1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24530606
PKM RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216198 12620389
STRN PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2CA RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15950189
PPP2CA TNNI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15769444
YWHAG RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
STRIP1 SLMAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
SNRNP200 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SNRNP200 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
STAT3 SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19474327 21940958
YWHAB SPTAN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8009988 20598904
TAOK1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29673168 23431053
STRN4 STRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 STRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRIM24 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0813177106 19556538
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB6 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL4 RPS18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
TUBB1 TUBB6 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MDM4 UBB â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
HSPA2 HSPA8 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
FOXO3 TP53 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
OTUD7B UBB â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
TP53 HSPA9 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5219502 17184779
EIF3CL RPS3 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
LATS2 SAV1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CBL YWHAB â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
XRCC6 ABL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 9798959
AKT3 AKT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AKT2 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SAV1 AMOT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30266805 24255178
CRY1 PTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25756610 23133559
CUL5 PRDX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33712558 21145461
TRAF6 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27507811 17353931
ILK DDX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 23455922
GTF2I XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30585729 26344197
KIF2C KIF2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
XRCC6 MSH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 21075794
MSH2 RAF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 31980649
PRDX2 PCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 26344197
STK3 PRDX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23455922 23386615
RNF31 UBB â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
STK3 MOB1B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 21808241
HSPA1L HSPA2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ARF1 COPB1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CDK3 AKT2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC6 MCM7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 23703321 26186194
MOB1B MOB1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24366813
STK4 RASSF1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
RASSF6 STK3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
RASSF4 STK4 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
LATS1 STK4 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
IPO4 KPNB1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
AKT1 MSH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24412244 28205554 28628118
LATS2 AMOT â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24255178 24225952 24101513 24106267 30266805
STK4 RASSF5 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
IPO5 KPNB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MOB1B STK3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
AMOT NF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
MTA1 TP53 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
HDAC6 UBB â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
HSPB1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
RPS18 RPS3 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
AKT2 AKT1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 11546794 11278835 12149249 14500673 9736715 12176337 28514442 11445557
NF2 AMOT â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
MAPRE1 KIF2C â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 7256098 19543227
LATS2 LATS1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 24255178 21233212 32707033 34079125
STAT3 STAT1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6730629 8662591
RPS3 RPS4X â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
MAPRE1 PPP1R13L â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
AKT1 FOXO1 â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 21798082
AKT1 FOXO1 â—¼   RELOCALIZATION ✅ - 0.85 0.85 Signor 18423396
HUWE1 HSPB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25277244 25147182
STK4 STRN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24255178 24366813
DDX3X EIF3B â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CKAP5 MAPRE1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
RPL4 SRP54 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HSPB1 DAXX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15911090 25241761 11193028 31615977 11003656
FGFR1OP2 PPP2CA â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GABARAPL1 SQSTM1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ILK RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 23455922 26496610
STK3 STK4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FEN1 MSH2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
LATS2 MOB1B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
STK3 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 23431053
EIF3B RPS18 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3B RPS4X â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
FYN CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 12640114
HSPA9 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HDAC6 SQSTM1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ABL1 RAD51 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
RASSF4 STK3 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ARF1 ARF4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
ILK AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11825911 11546794 11313365 18339839 11278835 12149249 14500673 9736715 12176337 11445557 16189514
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AMOT LATS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24255178 32292505 24101513 24366813 30266805 34079125
COPG1 COPA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 14729954 26344197 22939629 28514442 9751720
FOXO3 SMAD4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15084259 21532621
ILK HSPB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25852190 17353931
HUWE1 UBB â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RAF1 KEAP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 31980649
MOB1B LATS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 16674920 19739119 24255178 24366813 18328708 28514442 34079125
STK4 MOB1B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24255178 22863277
PCBP1 PTBP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27684187 16713569 26344197
PCBP1 PCBP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23640898 27684187 16713569 26344197
CASP3 PARP1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
DAXX RASSF1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CSE1L KPNB1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
KEAP1 MCM3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
STAT1 STAT3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MAPK8 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MDM4 YWHAG â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DNAJA1 HSPA8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PRDX1 PRDX2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HSPA5 SQSTM1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
RPS18 RPS4X â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
H2AFX PARP1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AKT1 FOXO1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RAF1 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
LATS1 ZYX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10831611 16713569
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
TP53 CUL7 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8415349 22653443
RAF1 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7517401 16189514 16713569
SAV1 LATS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25670202 25692647 24255178 34404733 30266805
STK4 MAP1S â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23455922 24255178 24366813
STK3 MAP1S â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23455922 32707033 24255178 24366813
STK3 MOB1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23972470 31941533 24255178 18362890
STK3 MOB1B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32296183 24255178 19919647
XRCC6 MSH6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30585729 22863883 21075794
PCBP2 PTBP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10772858 16189514 16713569
STK3 RASSF5 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 24981860
STRN3 SLMAP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26496610 24255178 18782753 24366813
STK4 SLMAP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23386615 24255178 24366813
SLMAP STK3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25416956 33571521 32707033 24255178
SLMAP STRN4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24255178 24366813 26344197
MCM4 MCM7 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
RAD51 TP53 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
STK4 SAV1 â—¼   UP_REGULATES ✅ + 0.89 0.89 Signor 16930133
CTNNB1 FBXW11 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
H2AFX XRCC6 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
DAXX TP53 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
KIF2C MAPRE1 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
GABARAPL2 SQSTM1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
FOXO4 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11896584 11313479 11689711
TRAF6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34938598 19713527
AKT2 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20231902
AKT2 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19593530
AKT2 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23431053
AKT3 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20231902
AKT3 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19593530
AKT3 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23431053
AR CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22038727 20610535 23554843
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
TRIM24 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9115274 19909775 16713569
CASP3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9348292
CASP3 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278283
CBL PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
STAT3 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20830236
CUL7 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 DDX3X â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24180280 23584477 21325288
TP53 EIF3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
FBXW11 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 14988407
MST1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20028971 16751106 12040186
GABARAP SQSTM1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HSPA8 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
STAT3 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9880553 10440232 23228483
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
HSPA8 MAPK8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
STAT3 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16527988 14715258
RANBP2 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9398662 10473610
NF2 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26045165 24012335
NF2 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26045165 24012335
MAPK8 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16186825 9162092 17875933
TP53 MSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11350971 8630028
MST1 RASSF5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 16892067 19454690 23792360
PHLPP2 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20513427
RAF1 PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 502464200 8203796 16239230
RAF1 PPP2CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 502464200 8203796 16239230
STRN PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 29802198 10681496 18782753
PPP2CA STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21199877 23431053
PPP2CA STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21199877 23431053
RASSF4 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20920251 32296183 25416956
STRN SLMAP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26344197 26496610 24255178 18782753 24366813
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
STAT3 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16107692 23874455 20043094
STK4 STK3 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
TAOK1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22075148 29673168 23431053
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
MCM3 MCM7 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
SIRT1 FOXO3 â—¼   DEACETYLATION ✅ - 0.9 0.9 Signor 24003218
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ABL1 CBL â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
STK4 RASSF2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
STK4 MOB1A â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 21808241
CCT7 MOB4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CCT8 MOB4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KPNB1 RANBP2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MOB4 TCP1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CCT3 STRN4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CCT7 STRN4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CCT8 STRN4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
STRN4 TCP1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
FGFR1OP2 SLMAP â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
RASSF5 STK3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
RASSF2 STK4 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
SQSTM1 TRAF6 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
MSH2 MSH6 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
HDAC6 MSH2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 24882211 23703321
FEN1 MSH6 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CBL FYN â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
LATS2 STK4 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
MAP2K4 MAPK8 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
COPA COPG1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
UBB USP46 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
LATS2 STK3 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
MAP1LC3A SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MAP1LC3B SQSTM1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RASSF2 STK3 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPB1 COPG1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
COPA COPB1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
RASSF1 STK4 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
CCT7 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT8 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
RASSF1 STK3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MCM3 MCM4 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
AKT1 FOXO3 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
CCT3 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
AKT1 STK4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 19940129 17932490
STK4 SAV1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
HSP90AA1 RAF1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
LATS2 MOB1A â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
MOB1A STK4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CCT3 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
ILK PARVB â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CCT7 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
FOXO3 SIRT1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
SQSTM1 MAP1LC3A â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 19427866 7034152
YWHAB RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 19595761 8009093
STK3 RASSF2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
STK3 SAV1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
COPB1 COPG1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CCT3 CCT7 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
LATS1 STK3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
PARK2 UBB â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
LATS2 NF2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
TP53 MDM4 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 7290688 19521340
TP53 MDM4 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 7290688 19521340
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
COPA COPG1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
EIF3B EIF3CL â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MOB1A STK3 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
MCCC1 MCCC2 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
FYN CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9677430 8621719 12244174 7782294 10629042 119942 7642581 15556646 12231245 9311917 9535867 8626543 10799548 16713569 16503409 10092522 8900205 8995358 25814554 9890970 15190072 15208330 12941616 10829062 11239464 8662998 17094785
KEAP1 SQSTM1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PPP1R13L TP53 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
LATS1 MOB1A â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
SAV1 STK4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
LATS1 MOB1B â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
RPS18 RPS3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
SAV1 STK3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
RANBP2 RANGAP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RASSF5 STK4 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL4 RPS3 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
PARVB ILK â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 23455922 26344197 17353931 15467740 26496610 28514442 32707033 11402068
MSH6 MSH2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 9428522 15064730 26344197 8942985 10748159 22939629 25241761 26496610 14657349 10856833 9774676 10783165 10029069 19377479
CCT3 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT3 MOB4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT7 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 PPP2CA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPA COPB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CRY1 PER1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTTNBP2NL STRIP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTTNBP2NL PPP2CA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MOB4 SLMAP â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2CA SLMAP â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS3 RPS4X â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN STRN3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN TCP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN3 STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT3 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT8 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2NL STRN4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2NL MOB4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2NL STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2NL STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRIP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SLMAP STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SLMAP STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
STRN3 TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
FGFR1OP2 STRIP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
FGFR1OP2 MOB4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRN4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRN3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRIP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SLMAP STRIP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
FGFR1OP2 STRN3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FGFR1OP2 STRN â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL4 RPS18 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
STRIP1 STRN4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
STRIP1 STRN3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
STRIP1 STRN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM3 MCM4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM3 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MCM4 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS18 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM4 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LATS1 ZYX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10831611 16713569
AKT1 ZYX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17572661
STK4 H2BC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16885155 21212262 19747733 16462032 21646345 26759222 28740074 12757711
MST1 H2BC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12757711 21212262
ABL1 CBL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
FYN ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12522270 16787943 17570479 16912036 16076903 17474147 11847100
ABL1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 23331499 26546517 9461559 15279774 15033353 19427856 11684015 19285032 20841568 15330855 15212693 10212258 12359302
ABL1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8940193 17992189 20841568
ABL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16099633 25164010 17618275 24465953 20841568 17318191 20840866
ABL1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9525940 11494134 16713569 20841568 10829062 17389395 16955467 12604776 9890970 10391678 9195915 14725908 7925293 11997497 12522270 15556646 9102067 11239464 11994282 9174058 12475393 20675402 19380743 14604282 8626543 15212693 19823681
ABL1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8940193 16846476 20841568
ABL1 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17018282 17412694 11823473 17384675
ABL1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26721416 27618557 24868554 21715626 30903103 22590567
ABL1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27618557 22590567
ABL1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20651945 29262653 26148237 19075013 20841568 28690977 29348869
FOXO3 AKT1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
AKT1 FOXO3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
AKT1 FOXO4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
AKT1 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
FOXO3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19424579 23517348 21752881 22539004 11278373
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
PHLPP1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18511290 15899889 20576936 19797085 17386267 15808505 19261608
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
CAMKK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14500673 11445557 12149249 10833263 9859994 9868760 9368760 11278835 10226025
CASP3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17544405 12124386 10579725
PHLPP2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18511290 15899889 19797085 17386267 15808505 19261608
AKT1 COPS6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26318036 23095642
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
AKT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 21440011 10358014 11756412 10358076 31308176 20452955 21798082 11410590 20398329 11311120 11544290 28279977 10217147 15132996 23331499 19216069 11237865 20214616 11463845 16076959 11030146 12228231 9829964 18951090 23180781 17570479 10102273 18593906 17646672 16680151 12456685 18423396 18985696 18988627 17962350 30728292 16670091 18786403 14664696 25241761 16341064 11980723 10358075 2984676 13679577 12560069 10377430 11251083 17680028 2987962 17254970 11864996 20041807
AKT1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 19951971 11756412 11953455 11923280 20452955 21798082 20398329 21329882 10217147 11154281 11994454 23331499 10995739 19216069 20214616 11463845 21775285 20068231 9829964 17570479 10102273 18593906 17646672 16680151 18988627 21621563 15169778 17522590 25241761 23109003 11715018 19188143 15023346 17680028 26192618 11864996
AKT1 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 15911620 15998799 17570479 30680530 11707464
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
AKT1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16163388 18356162 16511560
AKT1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19369195 20231902 20086174
AKT1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 22619175 19369195 19737514 19940129 17932490 23431053 11805089 24872389 23893242 17726016
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 58.0 1.0 Omnipath 11756412 20452955 21798082 20398329 15538382 10217147 23331499 19216069 20214616 11463845 23180781 9829964 11313479 10102273 10518537 14690436 16680151 17646672 18988627 17522590 11896584 16272144 11689711 17680028 21620960 19664994 11864996
AKT1 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12740362 11042204 19593530 22983196 17510053 23397142
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 EIF4B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18836482 17570479 25749412
AKT1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
PHLPP2 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17386267 19261608
PPP2CA AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15367694 18039929 19216069 10026142 10995457 18042541 20452955 18559511 18588945 16680151 16406523 18160256
PHLPP1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20576936 17386267 11507039 15808505 19261608
AKT2 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 19216069 11896584 17680028 11756412 16680151 20214616 11463845 21620960 19664994 20452955 9829964 16272144 20398329 11313479 15538382 17646672 10217147
AKT2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 17287208 20398329 21506126 20028971 12040186 18218901
AKT2 PCBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24072492 20154680 27648147 30086790
AKT2 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 19951971 19216069 17680028 11756412 17646672 20214616 11463845 20452955 9829964 20398329 10102273 18593906 16680151 10217147 19188143
AKT2 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 19216069 17680028 11756412 17646672 20214616 11463845 20705244 20452955 9829964 20398329 10102273 18593906 16680151 10377430 10217147
PHLPP1 AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9512493 17386267 19261608
PHLPP2 AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9512493 17386267 19261608
PPP2CA AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 15367694 18039929 19216069 10026142 10995457 18042541 20452955 18559511 18588945 16680151 16406523 18160256
AKT3 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
AKT3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
AKT3 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 19216069 17680028 11756412 17646672 20214616 11463845 20452955 9829964 20398329 10102273 18593906 16680151 10217147
AKT3 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15023346 19951971 19216069 17680028 11756412 17646672 20214616 11463845 23109003 20452955 9829964 20398329 10102273 18593906 16680151 10217147 19188143
NF2 AMOT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19615732 24366813 26045165 21481793 26549023 23414517
FOXO3 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16061480 17522055 18687691
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
HSPB1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19767773 17974989
CASP3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8626669 9535906 16713569 9208847
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
GAPDH AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 8872471
DAXX AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 27671201 17145710 15350595 15572661
MAPK8 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24424504 21512132 21820033 16282370
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
AR FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18391971 17202144 16713569 12482965
ARF4 COPB1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
ARF4 COPG1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
ARF4 COPA â—¼   PHYSICAL_INTERACTION 17.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
AURKB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 20959462 27933271 20847049 15469940 32873634 22611192 27496712
AURKB KIF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15630414 26148251 14972678 14960279 17567953 19632184 15064354
AURKB RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19887622 19276349
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
CASP3 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10998058 10082566 11684015
CASP3 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11907276 8090205 7596430 9875225 32223133 10438458 17167422 7774019
CASP3 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11278782 11278283 11517310 9545236
CASP3 SPTAN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 8940132 9624143 9712874 9811849 8910516
CASP3 EIF4B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11274152 10672017
HSP90AA1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
FYN CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 97.0 1.0 Omnipath 9525940 7642581 8626543 7782294 15208330 16503409 16713569 10829062 10799548 10934191 8900205 8551236 8662998 8995358 19734451 12604776 9890970 10592173 17570479 10629042 17094785 10092522 11997497 12522270 15556646 12244174 8621719 9102067 22880054 9311917 11239464 19904769 11994282 12941616 9535867 25814554 12231245 15190072
CNKSR1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15670823 23331499 15075335 15845549 9115393 11134016
CNKSR1 RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15670823 22830020 15075335
KPNB1 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
KPNB1 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
FBXW11 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23331499 9784611 22682247 10074433
FYN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 20026641 22264731 24511551 25241761 22340496 12640114 25803041 26509276
CTNNB1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 15905404 21071413 17254970
CTNNB1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17254970 15905404
CTNNB1 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17254970 15905404
DAXX HSPB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11003656 11274345 16406523 20452955
SQSTM1 DAXX â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 12702723 15340068 16252010 16498403 20531300 21981924 23069999 25002027 26587781 28574505 9184224
HSPB1 DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 25241761 11003656 11193028 15911090
DAXX TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12954772 21482821 21134643 16845383 25241761 15364927 16713569 12482984 15339933 23038753
DDX3X PABPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18596238 21883093 22872150
DDX5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24219989 15660129 20876186 19626115
HSPA8 DNAJA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20084477 20809635 24012426 7828728 20072699
PARP1 FEN1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
FOXO3 FOXO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19244250 16100571 18202312 23509296 19690465
SIRT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 24003218 22013015 14976264 18235501 15220471 14980222 22395773 15788402 15692560
STK4 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19221179 18786403 21245099 21320536 22898666 29896440 18394876
MST1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18786403 16751106 21320536 29896440
FOXO1 SOD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18280257 12239572 10492402 15766528
MST1 FOXO3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12040186 16892067 19454690 20028971 23792360
FOXO3 SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24068327 15674333 12239572 15308628 24339251
FOXO3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23525956 20816089 15604409 23262029
PPP2CA FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19029949 15207915 20110348 17322870
STK4 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 27769056 22898666 18394876 28521392 16751106 18985696
SIRT1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 24003218 14976264 14980222 15126506 21713995 15917664
FOXO3 SOD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18280257 12239572 10492402 15766528
SIRT1 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 15126506 10102273
MAPK8 FOXO4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11689711 20959475 17570479 15538382 15212693
GABARAPL1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17580304 20562859 23022382 21691068 25416956 31053714 16189514 32296183 21617041 19250911
GABARAPL2 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17580304 20562859 23022382 17353931 24582747 25416956 33436498 31053714 16189514 32296183 21460636 19250911 21900206
PARP1 H2AFX â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 12607003 14726013 15175241 15459660 15703371 16581787 16697054 17088286 17116881 17303408 17713585 19208614 19364882 19772495 19847258 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9488723
H2AFX RAD51 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
H2AFX RAD51 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
STAT1 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9880553 21430289 12940076 10440232
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
STAT3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18266962 16189514 12559950
HSP90AA1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 25036637 19011619 16093354 8962087 18266962 8408024 23118896 22939624 24462205 16189514 17699868 20039095 16504566 20159553 17409432 16330544 15618521
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
HSPB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25241761 16169070 16713569 17184779
HUWE1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 15989956 19918835 19960022 19590512
IL2RG STAT3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11418623 12517932 12244150 27774606 12093291 12759422
IL2RG STAT1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11418623 12517932 12244150 27774606 12093291 12759422
IL2RG STAT3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10426994 11907067 12244150 12811837 15536084 16081783 16713974 16785506 19833085 20856220 21840487 23124025 24751819 7512720 7521688
IL2RG STAT1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10426994 11907067 12244150 12811837 15536084 16081783 16713974 16785506 19833085 20856220 21840487 23124025 24751819 7512720 7521688
SQSTM1 KEAP1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 15340068 16252010 20531300 21981924 23850759 25002027 26587781 26653790 26794443 27048822 28574505
KEAP1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 20452972 20495340 22872865 15983046
SQSTM1 KEAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 20378532 35044719 20495340 25416956 25939382 23117207 32075457 20452972 24322982 20562859 25910212 26043024 33397898 23795962 27631370 33603948 20421418 32296183 23242280 19615732 31169361 20173742 24011591 21482715
STAT1 KIF2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22951020
STK3 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22195963 29970086 19962312 15688006 30038061
STK4 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15688006
STK4 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 26898830 26578655 24255178 23431053 21808241
STK3 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26898830 21832154 15688006 23431053 21808241
LATS2 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21118956 25086053
MAP1LC3A SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 20061800 23022382 23459205 35044719 22963397 36036324 31053714 21045561 25921531 19250911 17580304 21628531 20204693 28740232 23640897 25686248 24100292 26075355 20562859 22658522 25984893 21460636 16286508 19427866 32296183 23989536 19021777 26268733 22714671 24998849 18653543 31366950 33436498 16169070 23239879 26754771
MAP1LC3B SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 18083104 23022382 35044719 26413874 25416956 22434781 31053714 24023838 19250911 17580304 23333919 20452972 24668264 28085563 21900206 20562859 20010802 25007327 32296183 33302793 24582747 33436498 16169070
TAOK2 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10660600 23331499 21614932 12738796 11274345 18855897
MAP2K4 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 17143273 10713157 11489946 7600581 8702918 17145710 13130464 23416355 10748139 8805275 18855897 10791986 9108083 19690332 95141073 18083107 9724739 12788955 9305638 23331499 19534553 15068801 7839144 10958661 21071413 23047924 11062067 21614932 9808624 12738796 15911620 15998799 9891069 11389443 18988627 9733714 11847100 18669648 16153436 10521444 15302099 16282370 11242034 14523011 12709432 26370088 9661668 10499589 7652575 16076903 7992057 16440308 7600582 17192257 9860979 15755722 12133933 16533805 19369195 9312068 9207092 10385525 12354380 12917261 8910292 9487126 9448004 10962008 12624093 11274345 11099046
TP53 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22607268 23376463 18374905 15958553 10854211 22353755
TRAF6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10346818 17965022 15692051 17947236
MAPK8 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27042197 20028971
MAPK8 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 23255093 17502367 21702955 19413330 11335711 9343414 23331499 15465816 12576423 11350938 20068231 12763138 9872331 18491316 18669648 10521505 18691976 20058876 15979846 14551213 10446219
MAPK8 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 7890696 15696159 15071501
MAPK8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 11108663 12531896 16713569 11283254 10706102 19651615 27147566 9724739 15538975 9732264 10581258 10436023 17570479 9393873 11896587 12514174 15580310 18813780 11078726
MAPK8 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 29578371 17081983 19007248 23434668 21540183 22622703 17924679 18187866 24296261 18838864 19413330 20027304 21471201 19107194 16964243 18669648 15302935
MAPK8 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24913968 14963018
MCM7 MCM3 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM3 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM4 MCM3 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM3 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM4 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM4 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
TP53 MDM4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16492744 18172009 21750655 20036872 21422812 17510313 9926934 18336191 19521340 20372076 10469568 20080970 22290440 21394211 23474762
MDM4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 74.0 1.0 Omnipath 25609649 18677113 28487147 24445145 30045945 20515689 26148237 22266850 11528400 19521340 21088494 16713569 15916963 9226370 12874296 21925390 16024788 25825738 24667498 16227609 24127580 8895579 20174603 18485870 12963717 15604276 25464845 12370303 10608892 23028042 25961923 26186194 17110929 22374672 26876197 17301054 23671280 21965653 17875722 22807444 10075736 19305137 17080083 29023092 27114532 20724842 10827196 19255450 24659749 28035068 23946421 20705607 19075013 21075307 12393902 11223036
STK3 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23972470 18362890 23431053 21808241 32513747 30038061
STK4 MOB1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 24255178 23386615 23431053 21808241 18328708
STK4 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18328708 22863277 23431053 21808241
STK3 MOB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19878874 32296183 23431053 21808241 18328708 19919647
MSH2 MSH6 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11307145 11948476 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 16879101 17129768 17303408 17395641 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261 23507534
MSH2 MSH6 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11307145 11948476 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 16879101 17129768 17303408 17395641 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261 23507534
RASSF1 MST1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21199877 14729613
MST1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12223493 11805089
PAK3 RAF1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10461188 10559936 10613909 10712905 11340065 11413130 11950587 9069260 9823899
PAK3 TNNI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12242269 15769444 20540949
PAK3 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 9069260 28225038 12719581 11376654 10801448 19465939 9234708 14575865 12551923 10712905 15664191 11733498 22592532 9823899 10205168 11897507
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
PHLPP1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20513427 23431053
PKM STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23791887 29127353 22901803 22306293 24115444 28978186 27080861 26542452
PPP1R13L TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17906639 21192816 18275817 16713569 15558054 12524540 23623661
PPP2CA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18039929 7604263 16680151 16239230 10995457 18042541 18588945
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
TP53 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513613 16322760 20802511 16398215 18769160
TP53 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 8617246 11002423 16713569 16322760 16983346 9380510
RAF1 YWHAB â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 YWHAB â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17353931 11697890 8702721 10433554 16189514 15664191
RAF1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24929361 15618521
RAF1 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 8085158 12620389 16093354 19595761 7882972 16041367 24255178 11697890 7935795 8702721 10848612 16189514 25852190 7644510 12360521 10620507
RANBP2 RANGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16204249 9019411 11854305 19526197 22464730 12192048 22194619 11709548 21518904
TP53 RASSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23779024 23038753 21364923
RASSF5 RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11857081 16713569 22195963
RASSF1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 20562859 17145710 24366813 26186194 14729613 26578655 24255178 20920251 22683405 15109305 23386615 17598981 21808241 23455922
RASSF1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17379520 24366813 26186194 14729613 22195963 24255178 20920251 21808241 21199877 19962312 20086174 32296183 17598981 29063833 18347058 17889669 23455922
STK4 RASSF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20562859 16892067 24366813 24255178 11864565 15109305 16713569 17517604 23455922
RASSF5 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 20562859 16892067 24366813 24255178 11864565 15109305 16713569 17517604 23455922
SAV1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20562859 17145710 24366813 16930133 26186194 24255178 20920251 21084559 23386615 25692647 17517604 23455922
SAV1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20562859 21988832 17379520 24366813 16930133 26186194 17145710 24255178 20920251 21084559 15688006 32296183 29063833 23455922
SIRT1 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17334224 16189514 15205477
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
TP53 SOD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23784082 20739073 10969820 16740634 22009531 24047462 20061391 15059885 20601193 11313974
TRAF6 SQSTM1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11274345 12620219 14660645 15125833 15340068 15721744 16252010 17948050 18264787 18758450 18922473 19161412 20531300 21981924 25002027 26587781 28574505
TRAF6 SQSTM1 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11274345 12620219 14660645 15125833 15340068 15721744 16252010 17948050 18264787 18758450 18922473 19161412 20531300 21981924 25002027 26587781 28574505
SQSTM1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15870274 27458013 10747026 27681126 16079148 16189514 18382763 16874300 11244088 17389358
STAT1 STAT3 â—¼   DOWN_REGULATES ✅ - 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19122651 17558387 22693070
STAT3 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 25609649 8662591 12070153 31462771 25241761 11722592 8710878 9794795 23268184 15284024 16189514 9535918 11594781
STK4 TNNI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18986304 22972900
TP53 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18172499 18695251 24667498 22056774 17290220 17592138 12421820 18413597 20173098 19556538 21857681 17470788 18359851 19805293 19196987 12640129
MSH6 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -4.08 4.07 PKG 28854368
MSH2 MSH6 â—¼   KO_DOWN_REGULATES ✅ - -5.11 5.1 PKG 28854368
MSH6 MSH6 â—¼   KO_DOWN_REGULATES ✅ - -5.12 5.11 PKG 28854368
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368