Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HSPA5 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL7 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EP300 RECQL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19299466
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
ABCE1 RPL23A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TERF1 ACD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0605303103 16880378
BRCA1 KPNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221252 8955125
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
EP300 MUC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1203339109 22869720
NBN EP300 â—¼   COLOCALIZATION 2.0 0.8 intact 21108945 8058069
MAP1LC3B FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 MAST1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 15146195
IPO5 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MUC1 LGALS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17090543 19556244
TNPO1 NUP153 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29970603 10202161
LAS1L NOL9 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RL7 IPO5 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20828572
HDAC1 IMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 23752268
RRP1B RL23A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20926688 24981860
RL23A RL7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 26344197
PCM1 GBRL2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24089205 28712572
MIRO2 IPO5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32877691
IPO5 RL31 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 19293945
RL31 RL13 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
VCAM1 RL7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RRP1B RL13 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 20926688
VCAM1 RL13 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RL13 RM34 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RM35 IPO5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RM34 IPO5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK2 ABCE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
BRCA1 TINF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34112789 29656893
FAF1 CUL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28443643 18775313
VCAM1 IPO5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
NOL7 IPO5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PELP1 IPO5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22190735
NOL9 IPO5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IPO9 TNPO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 26344197
LRRK2 LAS1L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
VCAM1 RAN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RPL23A SRP19 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
RL13 RL23A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22863883 22939629 26344197
RL23A TNPO1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11682607 9687515
RL13 RL7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22939629 26344197
BRCA1 TERF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19797051 29656893 34112789
PELP1 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11481323 33742100
KPCZ IPO5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
GBRL2 CUL3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25684205 20562859
IPO5 GBRL2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 20562859
IPO5 RL13 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 26186194 9114010
EP300 RAN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33742100 12649209
IPO5 KPNB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
NUP153 RAN â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
CFTR RAN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29924966 17110338 31324722
CFTR IPO5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29924966 17110338 31324722
ABCE1 RPL7 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
BAP1 IPO5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19615732 29686263
RAN IPO9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 26344197
LCA5 PCM1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26638075 34079125
LAS1L PELP1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
TUBGCP2 TUBGCP3 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
LRRK2 RL13 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31046837 24725412
PELP1 LAS1L â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 26344197 21326211 20442285 22190735 22939629
LAS1L PELP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PELP1 NOL9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26344197 22190735 28514442
OFD1 PCM1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24089205 26496610 26638075 34079125
NOL9 PELP1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ACD TERF1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
AIMP2 PARK2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
IPO5 IMA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 12861017
BRCA1 RL31 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26831064 11746496
NBN EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16051665 21108945
CSE1L KPNB1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
RL23A IPO5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11682607 9687515
BAP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23850490 16713569 9528852
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10426999 29656893 10783165 11504724 25659039 25939603 25184681 19244116 18171670 12124328
HDAC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 21102443 16713569
HDAC2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21946536 10220405 16713569
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
EP300 IRF3 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
TINF2 ACD â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383534 28514442 33961781 21044950 32296183 25910212 15231715 26496610 16880378 16713569 25416956 15181449 16189514
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TAF1D FAF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SENP1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15199155
IPO5 SENP1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
RAN RANBP6 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ACD TINF2 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
IPO5 RAN â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
TERF1 TINF2 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
RAN TNPO1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
KPNA1 KPNB1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
KPNB1 NUP153 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
TNPO1 RAN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 26344197 11024021 22939629 12384575 10944119 10353245
TINF2 TERF1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10581025 15383534 28514442 21044950 19487455 33961781 15316005 11701125 26496610 16880378 16169070 15133513 26186194 20811636 17589526 25416956 15181449 28216227
CSE1L RAN â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
LAS1L NOL9 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
FAF1 VCP â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
KPNB1 RAN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL23A RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
IRF3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9463386 9488451 11940575 9660935 21903422 10024886 11314014
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
ACD TINF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 16880378 15181449 25416956 21044950 15383534 31515488 26496610 16713569 15231715
BAP1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 9528852
KPNB1 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
TNPO1 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
TNPO1 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
KPNB1 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
DSCAM DSCAML1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18216854 10925149 11453658 18216855
EP300 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20471956 16051665 21108945
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
KPNA1 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11032817 26491019 10523667 26496610 9922449 9102465 17596301
TNPO1 KPNB1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19136967 19836308 21278340 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 KPNB1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
TNPO1 KPNB1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19136967 19836308 21278340 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 KPNB1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 KPNB1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
RAN KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 8909533 11024021 9214382 20658144 8576188 26496610 9102465 9135132 10944119 10037787 9045717
NUP153 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 35044719 10749866
KSR1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 17145710 19541618 27086506 17613518 11909642
LRRK2 TNPO1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 TNPO1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 TNPO1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
TUBGCP2 TUBGCP3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
TUBGCP2 TUBGCP3 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
RECQL4 FN1 â—¼   KO_UP_REGULATES ✅ + 1.74 1.74 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368
PMS1 PMS1 â—¼   KO_DOWN_REGULATES ✅ - -7.89 7.88 PKG 28854368