PARP1
|
H2AZ1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1429884
|
HDAC2
|
H2AZ1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18675384
|
HDAC1
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18691180
9650586
|
NUP188
|
NUP54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
NUP54
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
KPNA1
|
LMO4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
LMO4
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11751867
12925972
|
ESR1
|
AICDA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23181348
19139166
|
KPNA1
|
ANP32A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
ARNT
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17991765
|
STAT1
|
ARNT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19646959
|
ATM
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MDM2
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
19816404
21986495
|
BRCA1
|
KPNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5221252
8955125
|
BRCA1
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18025037
16331276
|
BRCA1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15574597
|
STAT1
|
CAMK2A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
YWHAZ
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
SOX2
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22469032
22855803
|
STAT1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17992189
|
MDM2
|
CDKN2AIP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18292944
|
YWHAZ
|
CSE1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
CSE1L
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
KPNA1
|
CSNK1A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12062430
5215475
|
CSNK1A1
|
YWHAZ
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
12062430
5215475
|
CSNK1A1
|
LEF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15747065
|
CSNK1A1
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19759023
|
RRP1B
|
CTCF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PARP1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23045548
23319653
|
KPNB1
|
DCAF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22500989
8328086
|
KPNA1
|
DCAF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22500989
8328086
|
DCAF8
|
RAN
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
22500989
8328086
|
YWHAZ
|
DFFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
DFFB
|
DFFA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
9108473
9422506
|
YWHAZ
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217069
15225635
|
STAT3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731598
14966128
|
EGFR
|
KPNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20692258
7987951
|
STAT1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10558875
22693070
|
EGFR
|
YWHAZ
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5217069
15225635
|
STAT3
|
EPAS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23991099
|
THRA
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11578528
11687272
|
GRM1
|
KPNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19084525
6979076
|
NPM1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219698
17318229
|
HDAC1
|
NUP50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HDAC6
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TUBA1A
|
HDAC6
|
â—¼ DEACETYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5215415
12024216
|
THRB
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16862226
18239067
|
HIF1A
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12606552
15385570
|
HIF1A
|
PKM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19828020
|
HIF1A
|
NR3C1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15699159
|
STAT1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19646959
|
PARP1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18314489
|
HIF1A
|
PKM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15379897
8089148
|
HSPA4
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
STAT1
|
HSPA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9880553
10440232
|
PARP1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TUBA1A
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TRIM28
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
YWHAZ
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
STAT3
|
KPNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19084525
6979076
|
YWHAZ
|
KPNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
KPNA1
|
TAF9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
KPNA1
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
KPNA1
|
TERT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
YWHAZ
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
KPNB1
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
LMNA
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
LMNA
|
NUP153
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
20561986
7893748
|
LMNB1
|
LMNA
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
YWHAZ
|
LMNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
NCBP2
|
NCBP1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
RUNX1T1
|
NCOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18952841
0802696105
|
PARP1
|
NMNAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0609211104
17360427
|
NPM1
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
TRIM28
|
NR3C1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9742105
|
NUP155
|
NUP43
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
NUP155
|
NUP188
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
NUP188
|
NUP62
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
NUP188
|
NUP205
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
NUP88
|
NUP214
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
RAE1
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17172455
0609582104
|
ORC6
|
ORC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0707260105
18234858
|
PKM
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
RBBP4
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RUVBL1
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
USP7
|
RELB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
RUVBL1
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
RUVBL2
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
RUVBL2
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18358808
|
STAT3
|
SOX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20132009
18447642
|
THRA
|
THRB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
1782215
17761769
|
TRIM28
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
YWHAZ
|
TUBA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
EGFR
|
TUBA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
TRIP12
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
PRPF19
|
TPR
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
NUP35
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
NUP153
|
NUP54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
KPNA1
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
NUP155
|
NUP188
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
CTCF
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
14759373
20038529
19450526
|
GATAD2B
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
NUP35
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
NUP205
|
NUP54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
LYAR
|
SREK1IP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
SOX2
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24048479
21532573
|
SKP2
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
6540196
18239684
|
HDAC1
|
ADNP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26496610
23752268
|
GOPC
|
BAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
BRCA1
|
CENPF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26831064
29656893
|
ESR1
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31527615
19805454
|
GOPC
|
CENPF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
MDM2
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28225217
22032989
|
CUL4B
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23238014
34026424
|
RHOB
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
EGFR
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24780295
28065597
|
EGFR
|
LMNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24780295
26320552
|
SENP2
|
LMNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29969578
34079125
|
RAN
|
NUP62
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
SOX2
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23667531
21532573
|
RHOB
|
TULP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
SOX2
|
UBR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30894683
23667531
|
KPNA1
|
NCBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
NUP155
|
NUP54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
NUP155
|
NUP93
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
NUP50
|
ARID2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
ESR1
|
LYAR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33731348
31527615
21182205
|
TRIM27
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
NUP35
|
NUP98
|
â—¼ CORRELATES
|
|
+
|
0.83
|
0.83
|
CCLE
|
31978347
|
GATAD2A
|
GATAD2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
HIF1A
|
SEPT9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
KPNA1
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
MDM2
|
NPM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
NUP188
|
NUP93
|
â—¼ CORRELATES
|
|
+
|
0.83
|
0.83
|
CCLE
|
31978347
|
NR3C1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
NUP153
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.83
|
STRING
|
36370105
|
LMNA
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24623722
29753763
30419336
|
LMNA
|
TPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
29568061
22412018
|
CUL1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
ANP32A
|
ANP32E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
PARP1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
34079125
26831064
25252691
|
ESR1
|
RRP1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31527615
21182205
|
ESR1
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
18451880
16645043
|
HIF1A
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
KPNA1
|
MACROD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
LMNA
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25948554
19734887
|
LMNA
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
29568061
25948554
30419336
22412018
|
NUP155
|
NUP205
|
â—¼ CORRELATES
|
|
+
|
0.84
|
0.84
|
CCLE
|
31978347
|
IPO5
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
NUP155
|
NUP85
|
â—¼ CORRELATES
|
|
+
|
0.84
|
0.84
|
CCLE
|
31978347
|
NUP155
|
NUP85
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
NUP155
|
NUP62
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
HDAC1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
NUP188
|
NUP85
|
â—¼ CORRELATES
|
|
+
|
0.84
|
0.84
|
CCLE
|
31978347
|
KPNA1
|
LMNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HuRI
|
32296183
|
NUP153
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.84
|
STRING
|
36370105
|
NUP85
|
NUP93
|
â—¼ CORRELATES
|
|
+
|
0.84
|
0.84
|
CCLE
|
31978347
|
BRCA1
|
TOP2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25184681
15965487
|
CALM1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
CUL4B
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25189618
34026424
|
CUL4B
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
34026424
25189618
30737378
|
PARP1
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
34079125
16204234
20596014
|
HDAC2
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25241761
11641274
|
STAT3
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18985005
23604114
15735682
23991099
|
LMNA
|
NUP50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
29568061
24927568
22412018
34079125
|
STAT3
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
6730629
8662591
|
NUP205
|
NUP85
|
â—¼ CORRELATES
|
|
+
|
0.85
|
0.85
|
CCLE
|
31978347
|
ANP32A
|
VPS72
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
HDAC1
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
EGFR
|
XRN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24780295
24189400
|
CUL3
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26344197
21145461
|
MDM2
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24804778
20708156
|
BAP1
|
IPO5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19615732
29686263
|
CUL3
|
PLRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26949739
21145461
|
CUL3
|
NUP50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26344197
21145461
|
ESR1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23874500
11429412
|
ESR1
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31527615
25303530
|
PARP1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19470756
34079125
16204234
20596014
|
HDAC1
|
NR3C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
PARP1
|
TOP2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20085707
34079125
|
NUP54
|
TPR
|
â—¼ CORRELATES
|
|
+
|
0.86
|
0.86
|
CCLE
|
31978347
|
HDAC1
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.86
|
STRING
|
36370105
|
NUP205
|
NUP93
|
â—¼ CORRELATES
|
|
+
|
0.86
|
0.86
|
CCLE
|
31978347
|
NUP62
|
NUP54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
27194810
32296183
25416956
8045926
21516116
28514442
16189514
|
TPX2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22110403
25184681
29656893
|
EGFR
|
STAT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31980649
25402006
24658140
|
EGFR
|
STAT3
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
22693070
|
GATAD2A
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
PHB2
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24051437
15173318
15140878
|
LYAR
|
RRP1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19710015
20926688
17353931
|
PHAX
|
NCBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26496610
29101316
24981860
|
NCBP2
|
PHAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
SOX2
|
NCOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
35140242
28794006
23667531
21532573
|
NCOR1
|
RUNX1T1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
PRPF31
|
RUVBL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
NUP62
|
NUP88
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
CALM1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
HIF1A
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
PHB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
HIF1A
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ATM
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
NUP155
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
HDAC1
|
RUNX1T1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
GATAD2B
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
GATAD2B
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
TPR
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12802065
11248057
|
DCAF8
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
33288900
21145461
16949367
28514442
31155351
31973889
|
ESR1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11887937
17284441
20935677
28065597
16713569
|
TADA3
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20413580
12034840
18089809
31527615
|
GATAD2B
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
SEPT9
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19251694
16424018
24067372
23977378
|
GATAD2A
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
ESR1
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CDKN1B
|
COPS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
CSE1L
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
STAT1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
HDAC6
|
TUBA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
GATAD2A
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
BAP1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23850490
16713569
9528852
|
RBBP4
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10220405
26831064
16713569
|
STAT1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10792030
16713569
|
HDAC1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10220405
21102443
16713569
|
HDAC2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21946536
10220405
16713569
|
MDM2
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12897156
17545634
10766163
11178989
16713569
31012223
|
HDAC1
|
TOP2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11062478
11136718
|
NUP88
|
NUP62
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
28514442
32296183
26344197
|
KPNA1
|
POLR3C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
COPS5
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
KPNA3
|
POLR3C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
GATAD2A
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
KPNA3
|
NMNAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
NCOR1
|
THRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
KPNB1
|
NCBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
LMNA
|
LMNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
KPNA3
|
NCBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
NCOR1
|
THRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
MTA2
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10444591
25123934
12124384
19703393
24981860
26344197
22939629
12354758
11297506
|
MBD3
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
21670149
24981860
22939629
26496610
11102443
17827154
24048479
26344197
21258344
16428440
12354758
28514442
27068747
19041848
10444591
25123934
12124384
23752268
|
MBD3
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25123934
24981860
20388487
26344197
21258344
22939629
12354758
23752268
17827154
26949739
19041848
|
ESR1
|
H2AZ1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19515975
23108396
20023423
|
HDAC1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14988403
11929879
16189514
16713569
|
LMO4
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11751867
12925972
16713569
|
CAND1
|
CUL1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
12504025
12504026
15537541
|
EPAS1
|
ARNT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9079689
11018023
19845609
14668441
33591636
24981860
32461361
15192019
16181639
23275444
23434853
26160453
23796364
19129502
|
ESR1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11493692
27977889
10334989
11782371
16713569
17505062
15674350
19887647
20060929
11244506
16860316
17392432
31527615
16061635
16260778
12400015
1244506
25499220
29367421
|
BRCA1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
CTCF
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15252835
24725430
19466541
|
CUL3
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21145461
21249194
22013077
16449638
22405651
26286618
12609982
|
CAND1
|
SKP2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
12504025
12504026
15537541
|
HIF1A
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19342889
20138114
19940121
|
ESR1
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17163418
17681750
|
COPS5
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18926707
17879958
|
COPS5
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11707426
18926707
|
CUL3
|
HDAC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
15467454
15688063
17312394
|
STAT3
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18367518
21590492
23504318
|
NCOR1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16469706
17400812
12145334
16713569
12738788
21182203
24051437
|
STAT3
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21546410
|
HIF1A
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24015760
16511565
21148070
11641274
17273746
|
HDAC1
|
TRIM28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18381204
21669397
|
MTA2
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10444591
20714342
19703393
18451879
12920132
26344197
21258344
31980649
24981860
22939629
12493763
11102443
19686092
23752268
11297506
30737378
26949739
|
STAT1
|
IRF9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8943351
17923090
24065129
|
STAT2
|
IRF9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9242679
33961781
17923090
24065129
21903422
8943351
28514442
|
STAT1
|
IRF9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22951020
|
NUP50
|
KPNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
31515488
32296183
25416956
|
RANBP2
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9398662
10473610
|
TERT
|
LEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
19571879
11532957
21654818
|
LMNB1
|
LMNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
21346760
32814053
25948554
11792809
31467278
34079125
19727227
24623722
30419336
21988832
22412018
26524528
26264872
29568061
16189514
29997244
30021884
|
TRIM28
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16107876
|
NUP88
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
28514442
22480613
12589057
|
RRP1B
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19710015
20926688
34079125
|
RUVBL1
|
TERT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18358808
|
STAT2
|
STAT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
35140242
8621447
17923090
10446176
24065129
12048190
8605877
10490982
15825084
28514442
9724754
26966684
31836668
|
STAT1
|
STAT2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16918696
19122651
|
GATAD2A
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
NUP155
|
SEH1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
KPNB1
|
NUP62
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
GATAD2B
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
NUP188
|
NUP205
|
â—¼ CORRELATES
|
|
+
|
0.91
|
0.91
|
CCLE
|
31978347
|
KPNB1
|
RANBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
MBD3
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
CAND1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
COPS5
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
IRF9
|
STAT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CDKN2AIP
|
XRN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
RUVBL2
|
VPS72
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
MDM2
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
CDKN1B
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
KPNA3
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.92
|
STRING
|
36370105
|
NUP205
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
EGFR
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IPO5
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
NUP188
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
NUP155
|
NUP205
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
NUP205
|
NUP62
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
NUP54
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
MTA2
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
6613464
18451879
|
KPNA1
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
MBD3
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
KPNB1
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
NUP43
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
HDAC1
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
958.0
|
0.95
|
STRING
|
36370105
|
CUL1
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17290223
5219620
|
NUP153
|
NUP50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
CAND1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
KPNB1
|
NUP153
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
MTA2
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
HDAC2
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
COPS5
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
HDAC2
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
HIF1A
|
ARNT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
12391259
10085255
16954218
7836384
17916562
26496610
8663540
34592152
14764593
20603618
14668441
21512126
11606485
26350169
9079689
24056783
19845609
27684187
11782478
19168635
23363003
26160453
28628118
15850782
17197389
21620138
15833858
23086815
24434214
20458141
18024476
23458834
12810720
28514442
15347669
9704006
27320910
20562859
11829741
15031145
21435239
20049704
15479785
20932347
12393189
11025203
16861921
9159130
10671489
16520375
15615775
17213817
28205554
23796364
15319539
11593383
19251694
20699359
|
RBBP4
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
21670149
24981860
22939629
26496610
34518534
11302704
11102443
27705803
17827154
10734134
10220385
9885572
10471499
26344197
21258344
12091390
9150133
16713569
11602581
12920132
20127688
9790534
17643391
11470869
19686092
12943729
9150135
28514442
16189514
27068747
10444591
19703393
11171972
15451426
23752268
20585571
9520398
11118440
31435636
|
HDAC2
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
21670149
24981860
22939629
26496610
11102443
11919195
11777905
30737378
9885572
22416134
26344197
21258344
9804427
12493763
11287668
16713569
11466315
12920132
20388487
9790534
10581039
11739383
15987735
17894944
19182791
9150135
28514442
26949739
19041848
10444591
19703393
11804585
25241761
17956988
11564889
12032298
15451426
15297431
23752268
18059533
9520398
|
USP7
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
6799761
18566590
|
NCBP2
|
NCBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11545740
24981860
9933612
22939629
26496610
26382858
26264872
31448526
26344197
17190602
32814053
12374755
29997244
29101316
31467278
22365833
29395067
19668212
16189514
7478990
23665581
12434151
|
NCOR1
|
NR3C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
RUVBL1
|
VPS72
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
PCNA
|
SPRTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
NUP43
|
NUP85
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
NUP43
|
SEH1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
NUP85
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
PRPF31
|
SF3B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
HDAC1
|
MBD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
DFFA
|
DFFB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
CSE1L
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
KPNA1
|
NUP50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
NUP155
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
HDAC2
|
MTA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
NUP214
|
NUP62
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
PLRG1
|
SF3B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
NUP54
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
NUP214
|
NUP88
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
RAN
|
RANBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
NUP62
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
PRPF19
|
SF3B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
ORC4
|
ORC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
NUP205
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
NUP54
|
NUP62
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
HDAC1
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
NCBP1
|
NCBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NUP85
|
SEH1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NUP98
|
SEH1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NUP98
|
RAE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CAND1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
KPNB1
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PLRG1
|
PRPF19
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ARNT
|
EPAS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RUVBL1
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
ARNT
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
PCNA
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
BRCA1
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
USP1
|
PCNA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
16531995
18082604
18082605
18931676
19075014
19217432
19264559
19622404
19686080
23589330
|
EGFR
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
21220489
24655521
23542172
29140271
28157503
26725162
22238610
25825764
17115032
26719139
28102297
22692198
28666590
25073158
20670598
20587074
23593472
25675097
|
USP1
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
19264559
35324534
19686080
18082604
23589330
20353596
19622404
19075014
16531995
18082605
19217432
18931676
33619839
|
LMO4
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11751867
16713569
12925972
|
RELB
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9346238
15340381
16303288
8706131
|
NPM1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
22955283
31434245
16009132
12748172
|
CUL1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15668399
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
CUL1
|
SKP2
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15668399
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
CAND1
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
45.0
|
1.0
|
Omnipath
|
17145710
12684064
25435324
36076154
23019411
18826954
17290223
17438373
21169563
27542266
16036220
21145461
21778237
22474075
22767593
16861300
18173839
12504026
12504025
12706828
22405651
21249194
23453757
22013077
17439941
12609982
15537541
|
CUL1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15340381
15147722
12820959
12835716
11961546
11516665
15071497
15688063
|
ARNT
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
17213817
8816435
17197389
14764593
12393189
12810720
15319539
23363003
9079689
11829741
15479785
26496610
12391259
17916562
24434214
11606485
20562859
9704006
21620138
11782478
20932347
15347669
8927054
21435239
19168635
9159130
14668441
20049704
20603618
|
BRCA1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
MDM2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
PARP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
SLX4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21655083
17525332
|
ATM
|
TRIM28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
73.0
|
1.0
|
Omnipath
|
25128619
22496453
34194047
30323812
26158765
16862143
28607002
19584288
20858735
28851455
18285803
34419074
17833484
22491012
25404613
21642969
28439615
27364555
27602502
26671524
23096706
23935532
28739276
24754998
25905708
28847822
24461736
23318425
23346550
17178852
27432546
27820601
17942393
21868291
32060145
22205726
25846574
26293668
25533843
23034801
23352131
28249048
23633913
17525332
18657500
24794298
23645696
26212333
23050241
22715096
27376578
23370278
24657165
29540829
25173936
19071136
28847828
20424263
34518220
25956864
23554604
|
ATM
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
66.0
|
1.0
|
Omnipath
|
14654783
12383858
17936559
20651945
17303408
19816404
10611322
23150762
23277204
23386996
26416444
27258263
23002429
11331603
15865937
21556066
16163361
23708100
17570479
20514355
22264782
27177180
18265945
28690977
23847781
22264786
15140942
15964794
19788416
22624716
25201202
27462439
12607003
28050229
32350255
22649771
27956626
15459660
22976441
25247188
28904407
11877377
21859827
24534650
23405218
29290977
27568562
|
ATM
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
27486774
21490922
20932476
20188669
18583959
22435563
28626800
24957606
16497931
21872579
20932475
19917246
16965765
23063077
|
ATM
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
27245613
24681585
21095578
18971907
21095582
27027353
23573973
27068951
25956861
23707302
26942179
|
ATM
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
26927092
17303408
15159397
24746700
12024016
10866324
30197789
12919958
11114888
26745677
26383678
34301763
12427729
11313470
16163361
28035057
20068231
25939603
26320175
17570479
19683496
22743550
10608806
23802008
23847781
21203981
15964794
12183412
12607003
17525332
19996295
15459660
11278964
19651622
21706030
11877377
20952512
10373534
19622773
10550055
27170701
15212693
23704879
|
CAMK2A
|
ATP2A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7929371
|
BAP1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16713569
9528852
|
BRCA1
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
BRCA1
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
USP1
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
16531995
18082604
18082605
18931676
19075014
19217432
19264559
19622404
19686080
23589330
|
BRCA1
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11877377
21060331
19793801
21337561
15459660
20029420
|
BRCA1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11244506
12400015
15674350
10334989
16713569
11493692
|
EGFR
|
CALM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
17145710
19901323
20029029
12359306
16497976
25402006
17389395
18578522
16799092
20068231
3415247
7925415
18669648
12153558
24658140
17287340
14960328
18707149
17016520
|
CALM1
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17145710
3006921
17353931
20668654
|
CAMK2A
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
17389395
17081983
3138233
20166139
10347170
15901825
16799092
18691976
8226933
20068231
1309762
7805884
92065884
1956339
7505275
18669648
15302935
|
SKP2
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
47.0
|
1.0
|
Omnipath
|
26450989
20160477
12820959
18805092
16209941
24085301
11565034
15071497
18239684
22959436
17409098
22524983
15147722
12529174
23910095
15998794
16189514
22310285
35247157
12813041
21503567
20663873
22632967
10559916
11516665
11463388
12140288
15688063
15469821
20160482
15735731
15355997
15340381
12042314
15075339
21237244
19686743
32265224
|
COPS5
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
17145710
22350412
15688030
18926707
24671224
12082530
18202760
|
CUL4B
|
COPS5
|
â—¼ DEMETHYLATION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
19748355
18926707
16401342
18093314
23535663
23583660
22959436
16943200
23535662
|
KPNB1
|
CSE1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
14627704
17593948
17662023
18287025
19836308
21709260
21983832
7650486
8068174
9374532
9973469
|
KPNB1
|
CSE1L
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
14627704
17593948
17662023
18287025
19836308
21709260
21983832
7650486
8068174
9374532
9973469
|
CSNK1A1
|
RHOB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
27503856
18590726
|
CSNK1A1
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
14613942
19651622
17081983
15119949
18691976
20068231
18452278
9360956
16045749
12062430
18077418
19415658
|
CTCF
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17851529
17761849
25135475
17185360
|
CTCF
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
17267411
19806612
1632686
16326864
24174344
19914212
|
DFFA
|
DFFB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
17145710
11371636
9108473
17353931
12655299
10527861
15572351
10527860
9422513
9422506
32296183
19882353
10932250
10409614
|
ESR1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12894229
12421825
8200909
21705183
|
EGFR
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
23956138
12070153
20145033
14967450
20032199
21573184
25402006
10358079
23894143
14966128
24135280
25241761
14963038
24189400
15657067
24658140
15485908
15950906
18258752
31980649
9756944
22693070
12873986
15951569
15284024
|
EGFR
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
75.0
|
1.0
|
Omnipath
|
23956138
12070153
11839738
10918587
11447289
11997436
14967450
25402006
12040186
24797263
15173823
7543024
15322115
10358079
6321473
11294897
7690989
10982844
19568798
12637327
14585353
15199124
17496910
11438544
10748192
24658140
7657660
12817007
31980649
22693070
9355737
19615955
11152457
15284024
15567848
7592750
16488589
|
EGFR
|
HDAC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
20133936
31980649
22896792
20029029
24658140
21151618
25402006
23084749
|
EGFR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
20809984
17284441
16713569
11887937
|
HIF1A
|
EPAS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20513003
18174278
16924414
19030186
|
HDAC1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21655924
23242655
18316616
20101232
|
ESR1
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21411498
12122114
21693539
18519947
16690106
10805720
19360348
23409030
18754863
|
ESR1
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12897156
17166846
12750288
8324731
22787161
21169420
19578757
|
ESR1
|
RELB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17369819
20034404
19433448
|
ESR1
|
FOSL1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22514284
20034404
|
ESR1
|
MACROD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17893710
18206366
19403568
15691879
|
NCOR1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16469706
12738788
12145334
17400812
16713569
21182203
|
PHB2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15140878
17932104
26052702
10938099
12943695
|
TADA3
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12034840
20413580
18089809
16713569
|
HDAC1
|
NCOR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
15465827
16127449
21234400
22796940
|
HDAC1
|
HDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
10721693
11283614
11715018
11779693
11923280
12545156
12668723
14761977
15024084
15140942
15151915
15155580
15169778
15465827
15574337
15876864
16232121
17055429
17110379
17158541
17508028
17550342
17823410
19448627
19459846
20027199
20066118
20182602
20457558
20506250
20679392
20713526
20818389
21234400
21336307
21340684
21483453
21518799
21733352
21764762
2191300
21919891
22102694
22370643
22754780
22796940
23140366
23869868
6396087
9450543
9618481
|
HDAC1
|
HDAC2
|
â—¼ SHARES_COMPLEX
|
|
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
HDAC1
|
MDM2
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
10721693
11283614
11715018
11779693
11923280
12545156
12668723
14761977
15024084
15140942
15151915
15155580
15169778
15465827
15574337
15876864
16232121
17055429
17110379
17158541
17508028
17550342
17823410
19448627
19459846
20027199
20066118
20182602
20457558
20506250
20679392
20713526
20818389
21234400
21336307
21340684
21483453
21518799
21733352
21764762
2191300
21919891
22102694
22370643
22754780
22796940
23140366
23869868
6396087
9450543
9618481
|
HDAC1
|
NCOR1
|
â—¼ SHARES_COMPLEX
|
|
|
4.0
|
1.0
|
ACSN
|
15465827
16127449
21234400
22796940
|
HDAC1
|
MDM2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
51.0
|
1.0
|
ACSN
|
10721693
11283614
11715018
11779693
11923280
12545156
12668723
14761977
15024084
15140942
15151915
15155580
15169778
15465827
15574337
15876864
16232121
17055429
17110379
17158541
17508028
17550342
17823410
19448627
19459846
20027199
20066118
20182602
20457558
20506250
20679392
20713526
20818389
21234400
21336307
21340684
21483453
21518799
21733352
21764762
2191300
21919891
22102694
22370643
22754780
22796940
23140366
23869868
6396087
9450543
9618481
|
HDAC1
|
HDAC2
|
â—¼ UP_REGULATES
|
✅
|
+
|
28.0
|
1.0
|
ACSN
|
11283614
12545156
12668723
14673164
15151915
15155580
15465827
16232121
17018611
17055429
17508028
17550342
17563753
20027199
20713526
20818389
21234400
21577210
21685935
21733352
2191300
21919891
22370643
22514743
22796940
23140366
23869868
9618481
|
NR3C1
|
HDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15826950
16762839
18762022
18028994
|
HDAC2
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15653507
25241761
|
STAT3
|
HIF1A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
24.0
|
1.0
|
ACSN
|
10347215
10973499
12223527
14607900
14670306
15218058
15356132
15573129
16418395
18776941
18985005
19380816
20093776
20237412
20406969
20581311
21840487
23124025
23454751
23953057
24857661
27216177
28186502
7543512
|
STAT3
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19265129
18644974
16007214
20924113
17597020
23991099
|
HIF1A
|
TERT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18754863
15048086
17699105
16961934
|
HIF1A
|
HSPA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15794924
14726529
20068160
18844219
18683594
|
STAT3
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15735682
18985005
10973499
|
MDM2
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
15880652
25535359
12606552
25447306
17234751
19696166
10640274
|
IKBKG
|
RELB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
38.0
|
1.0
|
ACSN
|
11280761
11438547
11460167
12133805
12811837
14660645
15145317
15199157
15485931
15536066
15573129
16818229
16970925
17237376
17254973
17301840
17363905
17485448
17693255
18264787
18716620
19833085
20138012
20300203
21133840
21217011
21232017
21807870
22435554
23086447
23422957
23430059
24378531
24699077
24766893
24958845
2649237
28462531
|
IKBKG
|
STAT1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
38.0
|
1.0
|
ACSN
|
11280761
11438547
11460167
12133805
12811837
14660645
15145317
15199157
15485931
15536066
15573129
16818229
16970925
17237376
17254973
17301840
17363905
17485448
17693255
18264787
18716620
19833085
20138012
20300203
21133840
21217011
21232017
21807870
22435554
23086447
23422957
23430059
24378531
24699077
24766893
24958845
2649237
28462531
|
STAT2
|
IRF9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
29145629
7537377
9242679
23331499
8621447
24065129
17923090
21903422
15978943
8943351
12590259
17351669
21178011
21268015
|
STAT1
|
IRF9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
29145629
7537377
9242679
23331499
8621447
24065129
17923090
8943351
12590259
17351669
|
KPNA1
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11032817
26491019
10523667
26496610
9922449
9102465
17596301
|
RAN
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
10779340
8909533
11024021
9214382
20658144
8576188
26496610
9102465
9135132
10944119
10037787
9045717
|
NUP98
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9144189
25562883
9275187
|
NUP153
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
35044719
10749866
|
USP7
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
17145710
17936559
26460617
15916963
24462112
22056774
18566590
20816748
16402859
20713061
16943424
17380154
29236775
16082221
26238070
34799561
16845383
16474402
28406480
27452404
28196907
|
RAE1
|
NUP98
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
19615732
26186194
18832153
35096974
16036565
10209021
15851029
17172455
24927547
20498086
21467841
888800000819
|
PKM
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23791887
29127353
22901803
22306293
24115444
28978186
27080861
26542452
|
RANBP2
|
RAN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21988832
24855949
10078529
7603572
20547757
11470507
10318915
|
STAT1
|
STAT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
11134049
11830590
12193701
12223527
12796776
12811837
12967644
14607900
14764699
15814715
17016554
17513775
17559085
17689680
18272812
19833085
21263073
21930765
25960930
8683106
|
STAT1
|
STAT2
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
11134049
11830590
12193701
12223527
12796776
12811837
12967644
14607900
14764699
15814715
17016554
17513775
17559085
17689680
18272812
19833085
21263073
21930765
25960930
8683106
|
STAT1
|
STAT3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
46.0
|
1.0
|
ACSN
|
10485906
10754326
10820262
10952726
11134049
11399519
11830590
11875494
11964313
12193701
12223527
12433365
12796776
12811837
12907458
12967644
14607900
14607933
14660645
14764699
15465827
15644117
15699106
15814715
16127449
16878026
17016554
17260466
17404308
17485448
17513775
17559085
17689680
18272812
18345002
19833085
19879327
21097505
21263073
21930765
23390297
25960930
6357187
7594497
8683106
8871614
|
STAT1
|
STAT3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19122651
17558387
22693070
|
STAT3
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
25609649
8662591
12070153
31462771
25241761
11722592
8710878
9794795
23268184
15284024
16189514
9535918
11594781
|
STAT2
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
10490982
8621447
24065129
17923090
15978943
1502203
10446176
9724754
14722125
21178011
15825084
21268015
12048190
8605877
|
TRIM28
|
STAT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18381204
|
TRIM28
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18381204
18037959
|
ATM
|
LMNA
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.21
|
1.2
|
PKG
|
28854368
|
ATM
|
ATM
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.25
|
2.25
|
PKG
|
28854368
|
PARP1
|
PARP1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-7.28
|
7.27
|
PKG
|
28854368
|