Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H1-0 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-1 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 H1-3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-1 H1-3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
VIM CREB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DFFB DFFA â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 9108473 9422506
VIM DFFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DFFB PARP2 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
DFFB PTN13 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DFFB KAPCB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DFFB LRC15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK2 DFFA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
DFFB PKN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DFFB UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MGN DFFB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MGN UBB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PARP2 VIM â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
CASP3 DFFB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9108473 9422506
CASP7 DFFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10318789
KPNA1 KPNB1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
DFFA DFFB â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CASP3 DFFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11406587 25241761 12655299 18723680 9786842 9422513 9422506 16189514 9108473 11752060
CASP3 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11423904 10469173 11514563
CASP7 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11423904 10469173 11514563
DFFA DFFB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 17145710 11371636 9108473 17353931 12655299 10527861 15572351 10527860 9422513 9422506 32296183 19882353 10932250 10409614
KPNA1 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11032817 26491019 10523667 26496610 9922449 9102465 17596301
LRRK2 KPNB1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 KPNB1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 KPNB1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368