Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CHEK2 NSD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 NSD2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
NSD2 NSD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23011637 20599755
NSD2 AR â—¼   COLOCALIZATION 2.0 0.8 intact 19481544 7103716
NCBP3 NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
NUP188 NUP54 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NUP54 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPL10 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS11 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS6 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS8 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL4 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NPM1 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL3 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL5 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS3A MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL30 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP3K14 TNFSF13B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15585864 15644327
TNFSF13B MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17183360
RPL30 NSD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 RECQL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15674334
EP300 RECQL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19299466
RANBP3 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8285044 21960005
RANBP3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16314428
RAN RANBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 9637251
ACTB HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
HSP90AB1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20739403 20610535
AR RPL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 12390891
AR NOTCH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22347519 23145211
AR DNM1L â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10454563 21724752
AR HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 21125667
AR FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18391971
NPM1 ARHGEF9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ARRB2 NOTCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22162134 16284625
CHEK2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
FOXO3 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18344987 18424439
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
CCNB1 NUMA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7769006 23921553
ING1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15526165
CCNK NCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
CCNK NCBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
TP53 CCNK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11988847
TP53 CCNK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
CHEK2 SOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30576923 24647101
EP300 COPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8414198 23441852
EP300 COPS2 â—¼   ACETYLATION ✅ 2.0 0.8 intact 8414198 23441852
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
XPO1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19940019 18573912
DOT1L CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
CTNNB1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GLI1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19329935 19930158
NLK CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12556497
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CUL4B GPS1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
KPNB1 DCAF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22500989 8328086
XPO1 DCAF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22500989 8328086
DCAF8 RAN â—¼   COLOCALIZATION 2.0 0.8 intact 22500989 8328086
HTT DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMD2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TPX2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 DLST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17916908 21191025
MYC EIF4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18593934
EP300 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11896584
ETF1 RPL10 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPL5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPL30 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPS8 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPS11 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPS6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPS3A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
GLE1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS3A HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
TUBA1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RYBP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAE1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MORF4L2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RANGAP1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NLK HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PSMD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC IPO7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22284678
SREBF2 KPNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10397761 31875875
TP53 LGALS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
XPO1 MTA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
NFATC2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23858296 22333584
NOTCH1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10644343 16847353
MYC RAN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23468463 11085504
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
NCBP2 NCBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
NFATC2 NFATC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19564342 11786533
NPM1 TAF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 THOC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAE1 NUMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17172455 0609582104
NUP155 NUP43 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NUP155 NUP188 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NUP188 NUP205 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NUP88 NUP214 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAE1 NUP98 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17172455 0609582104
OTUB1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 PMS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMAD3 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PSMD11 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RANBP1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12649209 5216249
RPS8 RPS11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMAD4 RUNX1T1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21540640
RYBP SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21900401
SMAD3 TNFSF13B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18334541 22039367
XPO5 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
THRA THRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1782215 17761769
XPO1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17268548 17891139
PSMD11 PSMD2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ETF1 RPL3 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ETF1 RPL4 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EIF4A1 RPS6 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
EIF4A1 RPS3A â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
FZR1 TPX2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
NUP35 NUP98 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
RPL30 RPS8 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
EIF4A1 RPS2 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
PSMD13 PSMD3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
NUP107 NUP93 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
NUP155 NUP188 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ATM CHEK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 10973490
FOXO3 TP53 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ATM EXO1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 20019063
PSMD13 PSMD6 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EXO1 MGMT â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
NUP35 NUP93 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
NUP205 NUP54 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
EIF3M RPS3A â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
NSD2 NUMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22751105 31248990
MYC CUL4A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 20551172
CRY1 CUL4A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26431207 32235678
ACTB EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 33742100
BMI1 NCBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 NCBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
VCAM1 BUB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RAN CDCA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC CDCA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CFTR IPO7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
MYC CHD8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
U2AF2 CLK3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CUL3 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 21145461
DCAF8 XPO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22500989 26673895
EIF3M RPS6 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
EPAS1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23275444 22807441 15261140 25689462
VCAM1 EPS15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 FSCN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
TNPO1 IPO7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 26344197
MYC IPO7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
IPO9 TNPO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 26344197
MYC PSMD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RRP1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
MYC U2AF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
NCBP1 XPO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19262567 26673895
VCAM1 NUP93 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 PSMD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RAC1 STOM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 31871319
VCAM1 RAN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 STOM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
TAF8 TAF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VCAM1 XPO5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 XPO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 VDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RPL3 RPS6 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EIF3M RPS2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RPL10 RPS6 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EIF3M RPS11 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
NUP133 NUP93 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EIF3M RPS8 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
PSMD11 PSMD3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EIF4A1 RPS8 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
EIF4A1 RPS11 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
GLE1 RAE1 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
NPM1 RPL5 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
NUP155 NUP54 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
NUP107 NUP210 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
RPL4 RPS6 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RPL30 RPS2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
NUP133 NUP155 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
NUP155 NUP93 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EP300 ING1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12015309 16713569
PMS2 FAN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27880917 20603073 26496610 25659891 17148452 20603015
MYC XPO1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29467282 17314511 26673895 32140074
MYC PSMD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
RPL30 RPL4 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
COPS2 GPS1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
NUP35 NUP98 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RPS2 RPS6 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
NUP133 NUP85 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RANBP3 XPO1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CTNNB1 SMAD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
GLE1 NUP133 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
NUP188 NUP93 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
NCBP1 THOC2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
RANBP1 XPO1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
NSD3 MYC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31638140 28205554 28628118
CUL4A CDT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17079684 14578910 15448697
MYC ACTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29467282 11839798
DERL1 CFTR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26618866 16954204 16901789 18555783
FOXO3 EP300 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25609649 11896584 19592618
EP300 RAN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33742100 12649209
RPS6 RPS8 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
NUP155 NUP205 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
NUP107 NUP155 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ETF1 RPS2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
IPO11 RAN â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
NUP98 TNPO1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
RPL30 RPS11 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
NUP155 NUP85 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
NUP155 NUP85 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
PSMD1 PSMD13 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PSMD11 PSMD6 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
NUP188 NUP85 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
NUP107 NUP93 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RPL30 RPL5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
NUP133 NUP155 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
PPP1CC RRP1B â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
PSMD2 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
NUP85 NUP93 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PSMD12 PSMD13 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CFTR RAN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29924966 17110338 31324722
CFTR XPO1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
TAF11 TAF10 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23292512 14580349 29111974
TAF8 TAF11 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 14580349 29111974
RPL10 RPL30 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PSMD11 PSMD12 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
RPS3A RPS6 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
RPS11 RPS6 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PSMD1 VCP â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PSMD6 VCP â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PSMD13 VCP â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
RPL4 RPS2 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PSMD11 VCP â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TP53 XPO1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
NUP205 NUP85 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
RPL4 RPS11 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
NRIP1 THRA â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
PSMD1 PSMD11 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
NUP107 NUP188 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
IPO9 DISC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29961565 31413325
SMAD4 EP300 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18215124 25514493 10887155 22033265 9679056 14612423 9843571
EXO1 MORF4L2 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
RAN IPO9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 26344197
MYC XPO5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17314511 17353931
NUP107 NUP205 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
NUP54 TPR â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ACTB ACTR10 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
EXO1 PMS2 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
RPL10 RPS11 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
NUP107 NUP133 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RPL30 RPS3A â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RPL3 RPS2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
NUP205 NUP93 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
AMFR DERL1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CHEK2 TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
MYC IPO9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
DERL1 VIMP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MORF4L1 MORF4L2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NUP107 NUP85 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
COPS5 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PSMD1 PSMD2 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
RPL5 RPS11 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
NPM1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
NUP155 NUP93 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
RPL10 RPS8 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
NUP107 NUP35 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PSMD12 VCP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
RPL3 RPS11 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
RPL5 RPS2 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
TPR NUP98 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12802065 11248057
DCAF8 CUL4A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 33288900 21145461 32235678 16949367 28514442 19295130 31155351 31973889
CFTR PSMD2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29924966 17110338 31324722
DCAF8 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 33288900 21145461 16949367 28514442 31155351 31973889
FOXO3 SMAD4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15084259 21532621
SMAD4 NLK â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23602568 21988832
TNPO1 NUP98 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9144189 10875935 26344197
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PSMD11 PSMD13 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PSMD12 PSMD6 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
RPL3 RPL30 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
RPL10 RPL5 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RPL4 RPS3A â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
SMAD3 FOXO3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24920680 15084259 21532621
MYC NUP93 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21150319 29467282 17353931
RPL10 RPL4 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
RPS11 RPS8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
ATM CHEK2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PSMD1 PSMD6 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
PSMD3 PSMD6 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RPL10 RPS2 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
RPL3 RPS8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
RPL10 RPL3 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
RPL3 RPS3A â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
KPNB1 NCBP2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
KPNA3 NCBP2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
RPL4 RPS8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
COPS2 CUL4A â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
AR SREBF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 16541421
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
FOXO3 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18344987
ATM PPP2R5D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17525332 21460856
CTNNB1 CHD8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10921920 10944533 18378692
COPS2 CUL4B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
VCP DERL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 15215856
MYC EIF4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
SMAD4 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19516008 15525600 17452626
SMAD3 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16469949 12207925 15525600
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
MTA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11099047
MYC TAF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RPS6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RPL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333 11085504
NOTCH1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
NUP133 NUP107 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5219767 17363900
NUP133 NUP98 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
NUP88 NUP98 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 22480613 12589057
TP53 PMS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15781865
XPO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11074002 23331499
TAF3 TAF10 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17643375 33961781 15870280 11438666 23292512
RPS2 RPS8 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
VCP DERL1 â—¼   PHYSICAL_INTERACTION ✅ + 0.9 0.9 Signor 15215856
NUP155 SEH1L â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
RPL10 RPS3A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
KPNB1 RANBP1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
RPS11 RPS3A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ERBB2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
RPL5 RPS3A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
RPL3 RPL5 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
NUP214 XPO1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
RPL3 RPL4 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
NUP188 NUP205 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
IPO7 RAN â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
RPL5 RPS8 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
CUL4A GPS1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
PSMD1 PSMD12 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
NUP107 NUP155 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RPS3A RPS8 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
RPL4 RPL5 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
COPS2 CUL3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
RPS11 RPS2 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
PSMD1 PSMD3 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
EIF3M EIF4A1 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PSMD12 PSMD3 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
KPNA3 KPNB1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
GPS1 COPS5 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 7228517 19444310
GPS1 COPS5 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 24421388
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
NUP205 NUP98 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AMFR VCP â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NUP98 XPO1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NUP188 NUP93 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
RPS2 RPS3A â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
RANGAP1 SENP2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
NUP155 NUP205 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
NUP54 NUP98 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
RAN RANGAP1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
RAN TNPO1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
KPNB1 NUP98 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
NUP43 NUP98 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
NUP133 SEH1L â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
GLE1 NUP214 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
NUP133 NUP85 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
RAN RANBP1 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
PSMD6 PSMD1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 22863883 22939629 26344197 17353931
PSMD6 PSMD2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 17353931 22939629 22863883 28292943
XPO5 RAN â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 16189514 20951941 11777942
RAN XPO5 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CCNB1 FZR1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
NCBP2 NCBP1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11545740 24981860 9933612 22939629 26496610 26382858 26264872 31448526 26344197 17190602 32814053 12374755 29997244 29101316 31467278 22365833 29395067 19668212 16189514 7478990 23665581 12434151
TNPO1 RAN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 26344197 11024021 22939629 12384575 10944119 10353245
XPO1 RAN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 20026644 26344197 10779340 22939629 27613868 10944119 12070164 9323133 21909257 32585100
TAF8 TAF10 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 15870280 14580349 19114550 23292512 17375202 26186194 28514442
CUL3 GPS1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
NUP107 NUP43 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
NUP43 NUP85 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
NUP133 NUP43 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NUP43 SEH1L â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NUP85 NUP98 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
VCP VIMP â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DERL1 VCP â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
NUP155 NUP98 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
RPL10 RPS8 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPL10 RPS11 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPL10 RPS6 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL3 RPS11 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL3 RPL30 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TAF11 TAF3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
NUP54 NUP93 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL10 RPL3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
NUP214 NUP88 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL10 RPS2 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
RPL10 RPL4 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
RPL3 RPS2 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
RPL3 RPL4 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
PSMD6 PSMD3 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 18775730 26344197 17353931 22939629 22863883 28292943
RPL10 RPS3A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL10 RPL5 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPS3A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPS8 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPL3 RPS6 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PSMD1 PSMD13 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD1 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD12 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD13 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD13 PSMD3 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD13 PSMD2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD2 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NUP205 NUP93 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMD11 PSMD6 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMD11 PSMD13 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMD12 PSMD13 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PSMD3 PSMD6 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NUP107 NUP98 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
NUTF2 RAN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL10 RPL30 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL3 RPL5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
NCBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NUP107 NUP85 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NUP85 SEH1L â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NUP98 SEH1L â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NUP98 RAE1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TAF11 TAF8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS2 COPS5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
KPNB1 RAN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NUP107 NUP133 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NUP107 SEH1L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD1 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD12 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD2 PSMD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAN XPO1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPS3A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPS8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPS2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS2 GPS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS5 GPS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD1 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD11 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD12 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL30 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL30 RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL30 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL30 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL30 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS3A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL5 RPS11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL5 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS11 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS11 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS2 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS3A RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD11 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD11 PSMD3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD11 PSMD12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL30 RPL4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL30 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL4 RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL4 RPL5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS11 RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS11 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS2 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS2 RPS3A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS3A RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS6 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF10 TAF11 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TAF10 TAF3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TAF10 TAF8 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NSD2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19481544
TP53 MGMT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17564708 19846904 19056673 9780001 18555750 8616846 21957016 17234766 12503076 20525765 19531487
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
RANBP3 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20704570 23331499 19289081
AMFR VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20126661 22328510 16407162 16987818 17681147 26712280 16275660 21636303 17872946 18835813 19828134 22119785 23333620 23383273 26424800 21343306 21914798 16186510 15331598 17311810
FOXO3 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16061480 17522055 18687691
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12020745 20610535 14684616 18451309
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR NUP214 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR THRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14521927 21055159 20610535
RAN AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10400640 16713569 18565325
NRIP1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9368054 16527872
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
SMAD3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 11248024 11280774 12226080 16713569 11707452
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
ATM CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
ATM EXO1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
PMS2 ATM â—¼   UP_REGULATES ✅ + 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
ATM EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 15964794 11877377 17303408 18756267 16163361 15867354 23847781 23675572 25956864 26240375 11438669 24705021 12607003 18048416 17525332 20019063 15459660
ATM PPM1G â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26324325 17525332
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 176.0 1.0 Omnipath 26683224 17303408 28852018 10713094 20080130 27545311 9488723 15342622 23941746 26485758 28937603 15279786 24882580 10744722 15125777 25746763 18583988 28051860 17570479 16531125 21329876 23892398 19607708 16940182 26643553 20396397 28259974 25361978 17660363 15459660 19375317 25247188 16311512 23118481 20498628 22030216 25613496 22420423 9407949 17918214 12493754 20859824 26158765 15700044 27558808 11901158 27602502 20637859 16163361 20599567 23638118 16481012 12242661 23847781 12024051 15140942 11728459 12454775 16936775 25450480 28950914 26295265 20160490 22319212 24349411 18006705 20723763 18678890 12805407 20860841 23386996 24050180 11668173 27271602 29304495 12447382 24798733 9889122 23347679 18794134 21147465 21421565 26516160 17715138 21376743 19440053 12773400 10973490 17174984 26442630 15694385 11877377 29022904 18809224 11850621 18787700 12718885 19481982 22743550 20372057 15212693 16085488 19101576 29555944 25954303 24473398 18087292 16794575 24492479 24244353 19793801 25404613 21102523 29156743 23253087 16997395 7575488 25808488 20647331 18584027 21851590 21315088 23705030 15629715 29741650 21772273 11025670 18590585 26610585 15964794 29434792 20068082 23006513 19881958 19230643 12607003 24769180 25249630 15024084 19772495 25714019 18603484 25173936 23666059 19473886 27568553 22808196
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
TP53 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12874009 14627709 10051609 11313928 17942917 11892838 15710382 20395210 19470724 12379461 11071927 11522645 15737644 11162602
MYC CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 11522645 11983916 19470724
CHD8 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18378692 15367660 11744694
CHEK2 TP53 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10710310 10673501 10570149 10673500
CHEK2 EXO1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11438669 15459660 15810020 15867354 17296736 17464182 17568790 18048416 18566216 18756267 18931676 18971944 19686080 19788416 20019063 20126263
TP53 CHEK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15326376 19435816 10531348 19395378 15044452
CHEK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 18778462 25545885 16893723 15254178 18833288 23892398 12052256 18319725 25372714 15459660 20514219 25174607 28140789 17339337 22420423 18566216 20950777 20651945 15810020 15700044 22891162 17157788 11551930 18725978 10724175 15467443 23351141 20096447 11063934 11709713 15659650 12242661 10656682 15140942 20041275 11728459 18614044 12781359 22649771 18812180 11173129 10570149 15279785 20081365 20860841 11875057 22778557 19923893 24553354 22797063 26384650 23316480 15489221 19788416 10801407 21187893 9843217 9733514 10710310 24358900 21526939 23843721 29805302 9733515 25404613 12548019 21625617 10673501 11447225 17118344 26610585 19544417 28038466 12810724 25823026 15024084 17464182 15862297 19933256 20526329 12111733 20183804 23144912
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
COPS5 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11818334 27060206 16713569 17583730 14993265 1818334 24078030
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
FGFR1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17496910 25241761 22558232 11401320 12040186 19568798 14585353
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
RAC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19751508 28626389 26403202 19417647 22270359 16212495 16940750 12480336 11152757 29497040 30650643 19020303 15377999
ERBB2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17496910 7702605 7999105 22558232 14517306 11245482 11950845 12040186 19568798 23576562 14585353 23640056
CTNNB1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 15905404 21071413 17254970
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
MYC DFFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 18500556
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
MYC ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20920219 21627565 7906953 23421821 20716114
PMS2 EXO1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20970388 17426132 14676842 16188885 16143102
TP53 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22466965 18811981 16557594 24492005
MYC FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14519204 11896591 8376401 10421838
SMAD3 GLI1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
SMAD4 GLI1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11013125 11074002 11279127 11376132 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21098712 21614932 22331441 22652804 23784029 25374926 8515656 9389648
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
TP53 ING1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 14522900 17332334 10554029 9440695 16440314 11956069 10660101 10754201 16465410
ING1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9440695 16713569 12208736
IPO8 RAN â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22064859 9214382 18842624 24596094 23150874 23882114 24388755 15643423 19167051
TNPO1 KPNB1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19136967 19836308 21278340 21709260 21983832 7650486 8068174 9374532 9973469
TNPO1 KPNB1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19136967 19836308 21278340 21709260 21983832 7650486 8068174 9374532 9973469
RAN KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 8909533 11024021 9214382 20658144 8576188 26496610 9102465 9135132 10944119 10037787 9045717
NUP98 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9144189 25562883 9275187
KPNB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11294908 10846168
MAPK7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22046506 9461566
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC NUP155 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 18414489
MYC RPL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 14519204 11983916
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
PPP2R5D MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
NFATC1 NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19915002 18078995 15657420 18299389 16455648 11402342 11030334
NLK SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21988832 19690946 23602568
SMAD3 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 16713569 14638857 18988627
NPM1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 23443559 15144954 16740634 15310764 16376884 12080348
NUP214 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 12917407
NUP214 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 12917407
RAE1 NUP98 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19615732 26186194 18832153 35096974 16036565 10209021 15851029 17172455 24927547 20498086 21467841 888800000819
PPP1CB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16501611 15178317
PPP1CC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17274640 15178317 16501611
XPO5 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11777942 16189514 20951941
RANGAP1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7744835 8146159 9219684 16189514 10394366
RANBP1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 11832950 12649209 9111043 10811801 7603572 9315840 20805321 7891706
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
ATM LGALS3 â—¼   KO_DOWN_REGULATES ✅ - -1.03 1.02 PKG 28854368
TP53 NOTCH1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368
RECQL4 FN1 â—¼   KO_UP_REGULATES ✅ + 1.74 1.74 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
TP53 FN1 â—¼   KO_UP_REGULATES ✅ + 2.36 2.36 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
MGMT MGMT â—¼   KO_DOWN_REGULATES ✅ - -4.42 4.41 PKG 28854368