Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RUNX2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17517365 23073173
NFKB1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704864 11313951
BCL2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15210690
CCT5 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT5 COPS7B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDC37 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PCNA CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDKN1A UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7298683 19536131
CDKN1A DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19541625 0812254106
SOX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
ING1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16581770
STAT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17992189
DDB2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678110
PARP1 CETN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
COPS6 PTEN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
COPS6 EMD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CSNK2A2 PTEN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12297295 11035045
PARP1 CUL4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
RNF7 CUL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CUL5 SOCS2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PARP1 DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
DDIT4 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19557001 7255791
DHX9 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
DDX5 HNRNPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
MYC DDX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
HNRNPA2B1 DHX9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6542847 18519039
DHX9 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DHX9 DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DHX9 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FOXP1 RAG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21655267
SKP1 FZR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791267 10023660
FZR1 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791267 10023660
CDC23 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
FZR1 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
HNRNPDL HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC HNRNPDL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12695333
LGALS3BP MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAPK3 PARP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0508606103 16627622
EWSR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8164678 11423975
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC RPL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17599065 18032916
MYC HERC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC HSPA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC RPS20 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12808131 11085504
MYC H2BC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
STAT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10637230
PARP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PARP1 CUL4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
PARP1 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 RAD23B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
PCNA POLA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9660172 2165567
RAD23B ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RPS3 RPS20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPS3 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19229036 23349863
SIRT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27776347 28583374
PCNA XPC â—¼   COLOCALIZATION 2.0 0.8 intact 19279666 7263364
PCNA ENO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
PCNA ENO1 â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
DCUN1D3 CUL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
UBE2M CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17439941
HSPA1L NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA1L MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG4 RPL22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
STAT1 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19646959
SMAD7 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15632190 14761601
SMAD7 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15684397 1568439
DNMT1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19339266 21229291
BMI1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 19903340 8291464
CDC42 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16381926
PTEN BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19903340
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
HDAC3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15292260 18321663
FBXW4 CUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14603323 5216801
DCUN1D3 CUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
FBXW5 CUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14603323 5216801
CUL1 UBE2M â—¼   NEDDYLATION ✅ 2.0 0.8 intact 17914462 6175264
CUL1 ARIH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24076655
SKP1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7304783 18818696
BTRC SKP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SKP1 NFKB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
NCL MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA9 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL10A MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SLC25A5 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS14 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP3K1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218828 16845370
BMI1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6948569 19233177
GNB2 UBE2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COMMD1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17183367 5219492
UBC NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18617892 6804701
EWSR1 ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN3 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RPL11 RPL10A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPL11 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS14 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PABPC1 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NCL NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NCL MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10660576
CTNNB1 BTRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15473860 10882123
CTNNB1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17306568 12782598
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
HELLS DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17967891
HSPA8 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IARS1 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA9 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FBXW11 NFKB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
KRT24 TCHP â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
COPS2 CRBN â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
COPS7A CRBN â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CRBN GPS1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ABCE1 RPL10A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ABCE1 RPL22 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
COPS7B CUL2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
COPS2 DCAF11 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL1 DCUN1D3 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CCT5 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
DNMT1 UBC â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
MYC CBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CDC37 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16611982 24189400
CRY1 CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26431207 32235678
CRY1 C1QBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23133559 25756610
ASB4 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17636018 24337577
CUL4A DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 32235678
DDX5 DHX9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 26344197
ERCC6 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16107709 32355176
MYC CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 20551172
MYC DHX15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MYC DNMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
BMI1 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20668194 34316702
HELLS PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31417184
RBBP5 SOX2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30089852 35140242
CENPA RBBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20080577
UBXN7 CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
CUL4A GRWD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17079684 17041588
CUL4A NFKB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 30945288
CUL4A WDR26 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32235678 17041588
CUL4A SKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22474075
UBXN7 CUL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
UBXN7 BRWD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
CDT1 CUL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30018425 12840033
SFXN1 CDC42 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 29568061
NFKB2 UBC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14743216 18617892
GLMN DCAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HRAS RASSF1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
CUL1 FBXW4 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CCNG1 CUL4B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CCNG1 CUL4A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CRY1 CUL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25756610 34237211 17463251 33961781
CRY1 SKP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17463251 33961781 25756610
UBXN7 CUL4B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22466964 18775313 31973889
XPC RAD23B â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 34591642
FBXW5 CUL4A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22910413 17079684 18381890
CUL4A BRWD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 31973889 16964240
CUL4A GLMN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22405651 33961781
CUL2 GLMN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22405651 33961781
SEC13 TFG â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CTBP1 CHD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 24981860
COMMD1 CUL2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KRT24 KRT75 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
HIST1H3A ING1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
DDX5 DHX15 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CUL4A CDT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17079684 14578910 15448697
FBXW4 CUL1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25515538 23658844 29103612 25143387 14603323
CUL1 FBXW8 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
DET1 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 16949367 31973889
WDTC1 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 27113764 31973889 33961781 16949367
GLMN CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 31973889
DCAF5 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21145461 34026424 16949367 31973889
CUL4B HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
HDAC1 ERCC6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31722399 26496610 26030138
MYC HDAC3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23079660 31155734 22002311 18483244
CUL4A DCAF5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21145461 31973889 16949367 16964240
CUL1 GLMN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 22405651 33961781 22748924
CAND1 SKP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29499133 21145461 12504026
HDAC1 SAP130 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
ING1 RBBP7 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CUL2 UBXN7 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CUL4A DCAF4 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
ERCC6 UBC â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
DDB2 HIST1H3A â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
GPS1 COPS6 â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 24421388
CUL4B DHX9 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
CUL4B DDX5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
PCNA PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20129057 20302655 12930846 21690293 20303835
PARP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 16204234 20596014 19470756
CUL4A SFXN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 21145461
BTRC UBC â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
SOX2 WDR26 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23667531 28794006
PCNA UBC â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CBX1 CHD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20850016 27705803 24981860 21888893 28977666
CDC37 KRT75 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CUL4B GRWD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23238014 30945288 17041588
CUL4B SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23238014 27634302
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
DDB2 XPC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22039351 23319653 28760956 27203177 29604309 15882621
MYC MMS19 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 17314511 29467282
MYC UBC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 16996503 19131971
XPC PARP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 28760956
PARP1 NFKB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16204234 11590148 25609649 16799643
SUZ12 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 35016035 26186194 24981860 12435631 27634302 24457600 31281901 20075857
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
JAK2 STAT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11294897 15322115 11152457 12637327 7690989 20353823 19834108 14978237 15284024 10918587 24255956 7543024 12817007 7657660 11839738
SUZ12 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24457600 26344197 22439931
SOX2 HDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 21532573 23667531
FBXW4 SKP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23658844 27705803 20596027 33961781 22632967 22388891
CDC23 BUB3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 20360068
DNMT3B HIST1H3A â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
SOCS2 ELOB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31253590 23333304 28883622 21980433 30166453
CBX1 CHD4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS6 DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
COPS7A DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DCUN1D5 UBE2M â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SKP1 UBC â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DCUN1D3 UBE2M â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CUL4A DCAF11 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
COPS2 DDB2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CUL2 DCUN1D5 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CUL2 DCUN1D3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CTNNB1 SKP1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BTRC FBXW11 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CUL4B DCAF4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CUL4B DCAF11 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BTRC NFKB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
COPS6 CRBN â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DHX15 KRT75 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
BTRC NFKB2 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CRBN CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 24292625 31973889 33961781 21145461 27142104 27294876
DCAF4 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 28446751 31973889 26496610 33961781 21145461 30945288 16949367 32140073
DCAF8 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 33288900 33961781 31155351 21145461 16949367
FOXP1 CTBP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14701752 31041561
DNMT1 PARP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 27728808 23708667
RBBP7 ING1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 26186194 15451426 11784859
DCAF8 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32235678 31973889 33288900 33961781 31155351 21145461 19295130 16949367
DET1 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 17452440 16964240 14739464 16949367
CUL4A DCAF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 33961781 16964240 21145461 30945288 16949367 32140073
CUL4A WDTC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 27113764 31973889 33961781 16964240 21145461 30945288 16949367
UBXN7 CUL2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26389662 22537386 22466964 18775313 21145461
HDAC1 CHD4 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 26949739
HDAC3 RUNX2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15292260 18321663
CUL1 FBXW5 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
COPS7B CUL4A â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DDB2 XPC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BUB3 CDC23 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
COPS7A CUL4A â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COPS6 DCAF11 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
BTRC CTNNB1 â—¼   UBIQUITINATION ✅ - 0.88 0.88 Signor 10228155
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
JAK2 STAT1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
HDAC1 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20663877 20022962 15298701 19995069 17369852
FBXW8 CUL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21572988 21946088 25515538 17205132 29103612 21145461 22268729
MYC HELLS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 17314511 30415952
MYC SKP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12963825 21988832 17314511 29467282 30415952
MYC CHD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17314511 30415952 29467282
MYC CDK4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 28628118 21988832
CHD4 RBBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 22939629 9790534 25247294 33961781 26186194 28977666
ING1 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16288740 11682605 16713569 12015309
CDK4 PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 8259215 11254741 8101826
PCNA DNMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20940144 20613874 24958773 9302295 26496610 30301766 12354094 23708667 22606318 10888872
CUL4A CRBN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24292623 24292625 31973889 32235678 23983124 26231201 25860244 26990986 27029275 33961781 16964240 32132601 21145461 27142104 20223979 27294876
ING1 HDAC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23752268 18193082 16713569 26496610 33961781 12015309 11118440 15451426 11784859
FBXW5 CUL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23314863 23319600 25515538 29103612 25143387 14603323 21145461
CDT1 GRWD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25990725 18162579
FBXW5 SKP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
KRT75 TCHP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CTNNB1 FBXW11 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CTNNB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17404573 16288908 12782598
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CDC37 CDK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23455922 28514442 8703009 21871133 25036637 11867521 9150368 24189400 17353931 24292678 8666233 33961781 24981860 26186194 32707033 27339980 21675959
HRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
RPS2 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HSP90AB1 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
GNB2 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
COPS6 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A GNB5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EWSR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12560328 18757425 20153576
SIRT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23474493 15130752 21719763
SKP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16376880 25241761
CETN2 XPC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21962512 17154534 28514442 11279143 26638075 27880911 28760956 33961781 22939629
COPS2 CUL4A â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
ERCC6 CUL4B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
CUL4B DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17041588 31973889 18593899 26496610 30923324 33961781 26186194 21145461 30945288 16949367
SOCS2 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31253590 26264872 29997244 28883622 32814053 33961781 23098073 23897481 21980433 21145461 30833792
CUL5 ELOB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24438103 25499913 15574593 21145461 30166453 24076655 23806657 31253590 11384984 16530799 20463065 14564014 17351129 22479405 24402281 24390335 23098073 21119685 24390320
CUL4A DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 28514442 22118460 28035050 11564859 21145461 29262658 16473935 15811626 18593899 26496610 30923324 16964240 20368362 19295130 16751180 33759138 16260596 27203177 17609381 32985517 10585395 17041588 31973889 12732143 33961781 26186194 17626091 30945288 16949367
ERCC6 CUL4A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
FBXW8 SKP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10531037 26087183 21572988 18498745 21946088 27705803 31343991 17205132 12481031 20596027 33961781 15070733 22388891
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
ENO1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18490439 19219071 2191300
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
MYC RPL26 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 11085504
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RPL19 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333 11085504
MYC IMPA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC RPL22 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333 11085504
MYC SLA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
RPL11 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17599065 21118123
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
ENO1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
PARP1 CHD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20693977 26565020
DNMT3B RASSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19854132 12879017 18006804
CTBP1 RBBP5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HDAC1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11929879 16189514 16713569 14988403
CDT1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407242 30018425 24423875 16861906 16482215 18162579 26272819 16362051 30301766 30623174 16407252 21930785
CUL4A CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 21249194 22474075 12504025 15448697 18606781 31973889 12609982 27203177 12504026 19295130 16964240 21145461 22405651
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
CUL2 ELOB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19327355 24076655 31253590 12149480 15966899 12048197 15601820 25661653 11384984 24981860 18173839 21145461 9122164 30166453
STAT1 JAK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12223098 21239533
CTBP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 9650586 16189514 23752268 31041561 16713569 28947780 10995736 34147029 18765668 11022042
CHD4 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25247294 32744500 21258344 11102443 28977666 9885572 26496610 20585571 10220385 22075476 21670149 22939629 23752268 27616479 9790534 9804427 26949739 20693977 33961781 24981860 12920132 26344197
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
HDAC3 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12150997 15811852 15494311
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CAND1 SKP1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
NFKB1 MMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19303700 20352621 17498959
NFKB1 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24296733 18425349
TSC22D1 GNB5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TSC22D1 GNB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CTNNB1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16575901 16043491 24692107
IGF2BP1 BTRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19106159 16778892
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
DNMT3B TSC22D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
COPS2 CUL4B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CUL2 GPS1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CUL4A DET1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CDK4 HSP90AB1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
COPS2 CUL1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
CUL1 RNF7 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CRBN CUL4A â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
BANF1 EMD â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CUL4A GPS1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
GGA1 UBC â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RBBP5 UBC â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
FBXW11 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 25609649
CUL1 GLMN â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
ABCE1 RPS3 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
FBXW8 SKP1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CUL1 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CDK4 CDC37 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
CUL1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 17318178 5219675
SKP1 FBXW11 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5212166 10644755
CTNNB1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218183 16376880
DHX9 PABPC1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
ABCE1 RPS14 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 RBBP7 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CDKN1A PCNA â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
CHD4 HDAC1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ABCE1 RPS20 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBC WDR48 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RAD23B UBC â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
RBBP7 SUZ12 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
ABCE1 RPS2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
SNRPA SNRPD2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
RPL10A RPL26 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPL11 RPL26 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPL26 RPS3 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPL26 RPS20 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
SKP1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 9660940 6547997
SKP1 FBXW5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 31210753 23314863 10531037 26087183 23319600 30596474 19159283 27705803 20596027 33961781 22632967 32350066 15070733 22388891
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
HDAC1 ING1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
CUL1 GPS1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
CHD4 HIST1H3A â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
RPL26 RPS2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
DHX9 PCNA â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CBX1 HIST1H3A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
RBBP7 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19703393 10444591 21258344 11102443 9885572 17255935 10471499 26496610 25885317 22939629 9150135 23752268 9790534 27705803 33961781 26186194 19686092 15451426 12920132 26344197
HDAC1 DNMT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22274925 20613874 26794444 10615135 10888886 17707923 17934516 15870198 21670149 27593931 17967891 12473678 23708667
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
FBXW11 SKP1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
NFKB1 NFKB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14743216 27609421 21988832 17962807 15169888 35140242 25609649 15660126
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CETN2 XPC â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CUL1 FBXW11 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CUL5 SOCS2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
DNMT1 PCNA â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RAD23B XPC â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
RPL38 RPS3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
COPS2 CUL2 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CDK4 PCNA â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDC37 CDK4 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CUL5 RNF7 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RPL26 RPS14 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CUL1 UBE2M â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATXN3 UBC â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPL26 RPL38 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
LIG1 PCNA â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CDK4 CDKN1A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
COPS6 GPS1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL19 RPL26 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL22 RPL26 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPL11 RPS3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPS14 RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL10A RPS3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CDT1 PCNA â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
DCUN1D1 UBE2M â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL23A RPS3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL22 RPS3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DHX15 SNRPD2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL23A RPL26 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL19 RPS3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RPS2 RPS3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS20 RPS3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT5 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS7B GPS1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS2 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS6 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS2 COPS7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS7A GPS1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL19 RPL38 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BTRC CUL1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS6 COPS7A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL22 RPS20 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL22 RPL38 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL22 RPS14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL10A RPL38 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL38 RPS2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL38 RPS20 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL38 RPS14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL10A RPS14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL11 RPS14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS14 RPS20 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS2 GPS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 COPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL11 RPL19 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL19 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPL22 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL22 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL22 RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPL38 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL11 RPL38 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL11 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL11 RPL23A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL11 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL11 RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23A RPS14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS14 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS2 RPS20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL19 RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL19 RPS14 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL11 RPL22 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL23A RPS2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BTRC CTNNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BCL2 UVRAG â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10604474 11704864 16179260 17106237 17446862 17891140 18612260 22039431 22885520 23064052 23377657 23430059 23850759 27754749 8929532 9765397
BCL2 UVRAG â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 10604474 11704864 16179260 17106237 17446862 17891140 18612260 22039431 22885520 23064052 23377657 23430059 23850759 27754749 8929532 9765397
NFKB1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11313951 11704864 21725609 23178297 23572150
MYC BCL2 â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
NFKB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 16254192 11567031 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 12032828 19233129 16022909 18761399 18987666 15934930 21224428 16453001
MYB BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22101269 23675407 20237898 17823980 20659323 10692454 9096387 11675351 12384144 16088151 9823328
MYC BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8036017 17404573 12695333 24167291 18809243 19201832 16316993 19649202
MAPK3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9115213 10669763 9735392 11323415 21785723 9738012 10677502 23272207 25826088
PPP2CB BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15225643 9852076
CSNK2A2 CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20068231 15082798 19413330 12930845
RUNX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21913213 17438369 19179305 15107836 12391164
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
STAT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20738848 11162600 12239594 16449678 21307941 22591439 10023678 10866323
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
SMAD7 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10878024 15922743 20104486 12185267 15555279 11180003
DNMT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21229291 21572997 19056828 16276353 9588214 21868513 23658227
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
HDAC3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9618481 17550342 12545156 15155580 22796940 22370643 16533812 17508028
CDKN1A PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 67.0 1.0 Omnipath 23443559 25411249 20606006 8868473 15576034 16474839 25416956 20605778 16510448 18703516 23139781 11302688 11254741 26272819 16616141 21988832 11313979 7780738 17588519 12964161 25502805 10022118 8861913 16189514 26496610 16082198 8861969 17129767 18263614 26186194 22383522 22911014 7915843 7911228 27107012 23223023 17115032 32296183 19895794 18794347 19704162 10873631 9546435 8662825 31515488 21415862 9545252 11350925 12930846
CDKN1A CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 23443559 15169570 18850315 9658399 16962592 15232106 9632134 16189514 8622677 15695403 20102411 8242751 9464540 23007395 7626805 9106657 12383116 30193583 17556661 23543736 8756624
XPC CETN2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11900249 12648680 15703371 16697054 17884153 18199748 19809470 19847258 20211143 20457011 22615860
XPC CETN2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11900249 12648680 15703371 16697054 17884153 18199748 19809470 19847258 20211143 20457011 22615860
PPP2CB CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16596250 15380617
CSNK2A2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17570479 17287340 19413330 18669648
CSNK2A2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12700239 19141652 12432063
CSNK2A2 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17444818 19662498 15987703 16107342 11035045 12077256 11707428 12297295
PCNA CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
UBE2M CUL4B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 26460955 25314029 18206966 23201271 26906416 19250909 25531226 26344709
CUL4B COMMD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
DDB2 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15882621 22039351 19740755 29604309 23319653
CUL4A DDIT4 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDX5 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15298701 17369852 20022962
BANF1 EMD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25910212 22399800 11792822 25502805 17620012 31515488 32814053 32296183 12163176 11792821 16189514
CDC23 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
HRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MAP3K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 25241761 15315965 12049732 24135036
MAPK3 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21757713 21071439 19339977 19864431
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
MAPK3 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20041225 15950189 21738525
MAPK3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 27687725 19264160 29057206 25867060 19801668 25122769 21965325 25187572
MAPK3 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 8798443 8960373
MAPK3 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 9020136 9130707 26028036
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
RPTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
ENO1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10082554 10528225 17595061 10802057 19846662 11134351 23421821 10403782 18490439 14506152 20886042 7880838 2005901 9074493 18070418 21559732 9119380 20412594 10681589
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC IGF2BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21779431 18414489 21252116
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC NCL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10606642 24951594 12695333 14519204 25018006 11983916
MYC HNRNPA2B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12747840 20010808 12695333
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
MYC NDRG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11936845 18455888 10381566 21976667
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
PPP2CB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16987807 16680151 15048125
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
HRAS RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16810318 17145710 18596699 32814053 10998413
CDK4 RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22438769 18071316
RBBP7 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
RPTOR MMP2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17680028 18492954 19022819 19568798 19864431 19930715 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26597054 27328425 27510662 27572739 28216025
SIRT1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21071413 23331499 17098745
PCNA CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
LIG1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12171929 9649448 28073635 10559261
PCNA DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17991895 18384127 31235252 28073635 12354094 9302295
PCNA CDT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16407242 19231300 16362051 24423875 16482215 16407252 16861906
UBE2M CUL4A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 26460955 25314029 18206966 23201271 26906416 19250909 25531226 26344709
CUL4A COMMD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
JAK2 STAT1 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
JAK2 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 11839738 10918587 7888666 20353823 7543024 15322115 25950470 23331499 21071413 14978237 11294897 7690989 7504785 18988627 12637327 25535282 11438544 21576360 10748192 7657660 12817007 14984365 7504784 21207025 9355737 11152457 7615558 19834108 15284024 10982844 7592750 19787091
CTNNB1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 15684397 21071413 18988627
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
ING1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 15451426 20574448
HDAC3 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
NFKB1 CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
UBE2M CUL1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 16647857 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 21863050
NFKB2 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9346238 15340381 16303288 8706131
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 SKP1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 14685242 16189514 17290223 20832730 12504025 12904573 10230407 19933270 23324393 12504026 9636170 26540345 12609982 27697867 26753747 21145461 22474075 28007894 18818696 9736735 9990852 22767593 28152074 10023660 29070679 9827542 23951410 16357137 16759355 10713156 15452136 19270694 11027288 26474281 23770852 10648623 29499133 21249194 34499862 12628165 15966899 21169563 22660580 11961546 9430629 32313199 29863914 10230406 30653357 19945379 9663463 21778237 34237211 18094045 26976582 27705803 32249768 29103612 33961781 12684064 26725323
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
UBE2M CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 24949976 10713156 17914462 21247897 18805092 21946088 19245792 18826954
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
CUL1 RNF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11506706 10851089 10230407 16189514
NFKB1 SKP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
UBE2M SKP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 16647857 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 21863050
BTRC SKP1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SKP1 NFKB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9346238 15340381 16303288 8706131
SKP1 CAND1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 26632597 21463634 12504026 12609982 23535662 21863050
FBXW11 SKP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 25609649 10321728 25900982 15070733 12165731 10230406 21145461 26496610 24500709 10023660 10066435 25332235 19615732 19159283 27705803 10644755 25515538
CDC42 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7600581 17161586 23109003 9487126 7601337 9305638
BTRC NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12482991 10835356 11158290 11953428
CAND1 COMMD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
SEC22B SEC13 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 22013193 10982397 23378591 20545907 18843296 10825291 20679433 11035026
SEC13 TFG â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 22013193 10982397 23378591 20545907 18843296 10825291 20679433 11035026
SEC22B TFG â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 22013193 10982397 23378591 20545907 18843296 10825291 20679433 11035026
BTRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 23514615 17053147 22912335 17145710 27001857 20531388 18851830 12820959 24451375 18805092 25900982 11818547 16798748 19061640 19956254 23331499 24912152 19150432 22017875 24501426 28018973 16376880 21466614 27316454 19053519 26506240 14516475 25149538 10023660 22682247 10228155 9461217 24464578 18354482 26091241 10074433 12114015 9990852 14706645 18650423 25873176 19966869 25515538 20851351 22730322 24469040
FBXW11 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23331499 9784611 22682247 10074433
BTRC NFKB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 11994270 18617892 14743216 16303288
NFKB2 FBXW11 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9346238 15340381 16303288 8706131
SUZ12 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
UBE2M COMMD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 16647857 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 21863050