Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PARP1 CUL4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
HIST1H3A HIST1H3B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCNA1 CDKN1B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PRKCE APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCD APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EZH2 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21465172 19351856
CDKN1B CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDK4 CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CDK4 HIST1H1A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EZH2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980972 21765901
TAF1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18684994
PARP1 DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
XPC DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20368362
DNMT3B EHMT2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16371653 17584191
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
TAF1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17085686 9285713
NPM1 SUZ12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PELP1 NPM1 â—¼   COLOCALIZATION 2.0 0.8 intact 21326211 8149485
SNCA PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCA PRKCE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
PRKCE SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VPS37A VPS25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21757351 15218037
CDK7 GTF2A1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
NPM1 PA2G4 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EED SUZ12 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CDK1 CCNA1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 14681455 8565853 16009130 1628647 7799941
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
HIST1H3B UHRF1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
APP PPID â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
CUL4A WDR5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31155351 17041588
BMI1 PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 20668194
CDK2 CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
PAK4 CDK6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EED DDB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23238014 17041588
EZH2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
WDR5 TAF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32076268 15960975
DDB1 HIST1H3B â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HIST1H3B WDR5 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST1H3A NPM1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CBX6 HIST1H3B â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CBX6 HIST1H3A â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
DNMT3B HIST1H3B â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CCNA2 CCNA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CCNA2 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDK5 CCNE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 23455922 23602568 33961781
CCNE1 CDK7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDK1 CDK3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CENPA NPM1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
WDR5 DDB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33022573 31155351 17041588
PRDM1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19124609 22733990 14985713
PELP1 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11481323 33742100
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
WDR5 KAT2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 18838386
DDB1 HIST1H3A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CDKN1B CUL4A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CBX6 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
SUZ12 AEBP2 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
CCNB1 CDK7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 26186194 11113184
CCNE1 CDK4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9716181 28205554 28628118
CCNE1 CDK6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9716181 28205554 28628118
EZH2 DDB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27634302 23238014
SUZ12 DDB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27634302 23238014
DNMT3B EZH2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
PRKDC PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20085707 16794079 21575865 9398855
CDK2 TEN1-CDK3 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
PARP1 UHRF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31964471 24782312 34079125
VPRBP CUL4A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17609381 30166453 21145461 30590706 25532805 33355139 20870715 18606781 17630831 16949367 17079684 19295130 31973889
BMI1 EED â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23238014 24457600
CDKN1B CCNE1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591612
CDKN1B CDK1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591612
EP300 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33742100 30110629 20808282
PARP3 PARP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20064938 12640039
CDK6 CDKN1B â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 16160006
POLB UHRF1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
HIST1H3B KAT2B â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
LIMK2 LIMK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9089416 8980133 33961781
SET PTMA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16189514 15556635
LEO1 PAF1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
GTF2A1 TAF1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CCNA1 CDK1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
DNMT3B HIST1H3A â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
EZH2 AEBP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27634302 24981860 26496610 29348366 26186194 28068325 31281901 24457600 27705803 28514442
CDK5 CCNA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 23455922 33961781
CCNE2 CDK3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 9840943
CDK5 CDK3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 23455922 33961781 28514442
CENPA RBBP4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20080577 19410545 34079125
XPC PARP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 34079125 28760956
CCND2 CDK5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK5 CDKN1B â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 NAP1L1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
NAP1L1 NAP1L4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
H2AFY HIST1H3B â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CCNA2 HIST1H1A â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK1 EZH2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
KAT2B WDR5 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CDK5 CCNB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 25852190 26186194 28514442 23602568 32707033
CCNB1 CDK3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27030811 28514442
CDK4 CDK6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 28205554 28628118
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CCND2 CDKN1B â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CDK1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14681455 33961781 33422522 17679094 25852190 26496610 24302728 19483727 12853968 26186194 21308745 8463339 28514442 9053846 23602568 32707033
CDK7 CDK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23455922 25852190 16191191 10393546 15282296 23064645 11113184 8647086 8692842 7629134 16327805 15530371
KAT2B EP300 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12888487 22384255 9267036 12419806 21413932 20870727 33051058 8684459
EP300 PTMA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11967287 16713569 10891508
H2AFY PARP1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CDK1 CDKN1B â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CCNE1 HIST1H1A â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CDK6 CDKN1B â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
BMI1 CBX6 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CDKN1B TEN1-CDK3 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CCNA1 CDKN1B â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CDK6 CCND2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 16189514 9178893 30217970 11360184 28205554 16713569 28628118 23602568 11358847 10022865
SNCA CDK4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PAF1 CTR9 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18469135 20305087 19410543 33961781 24981860 26344197 22939629 26496610 20178742 26902284 21726809 30228257 16024656
LEO1 CTR9 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18469135 20305087 27173435 24981860 22532828 26344197 22939629 26496610 20178742 15632063 16024656
SUZ12 EED â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
RPS6KA5 EZH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCD PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19737086 9774685
CUL4A VPRBP â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CCND2 CDK2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
HIST1H3A UHRF1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
AEBP2 EED â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EZH2 EED â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
HIST1H3A RBBP4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
HIST1H3A NASP â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CCNE2 TEN1-CDK3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CCNE1 CDK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CDK2 CDK7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CDK1 HIST1H1A â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EP300 HIST1H3A â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CCNA2 CDK1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CTR9 CDC73 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
CDKN1B CDK4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5219242 17053782
CDKN1B CDK5 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 34591612
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
AEBP2 EZH2 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CCNE2 CDKN1B â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
H2AFY HIST1H3A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CCND2 CDK6 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
CDK2 CDK3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 28514442 23455922 26186194 33961781
PAF1 LEO1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
EZH2 RBBP4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CCND2 CDK4 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
CDK2 CDKN1B â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 17409098
NASP RBBP4 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CCNE1 CDKN1B â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
CDKN1B CCNA2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 34591612
CDK2 CCNE1 â—¼   PHOSPHORYLATION ✅ - 0.96 0.96 Signor 19561641
PAF1 CDC73 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
CCNE2 CDK2 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
CDKN1B CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 34591612
SUZ12 RBBP4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 27634302 24981860 20075857 22939629 35016035 15225548 24457600 27705803 31281901 28514442
EED RBBP4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CCNE1 TEN1-CDK3 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CCNA2 TEN1-CDK3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
AEBP2 RBBP4 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
HIST1H3A WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
AEBP2 SUZ12 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CCNB1 CDK2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
HIST1H3A KAT2B â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CDK4 CDKN1B â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CCNA2 CDKN1B â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
DDB1 VPRBP â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CDK2 CCNE1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 8978686 23455922 15980415 24771265 15670215 15514162 26496610 20837141 25728284 9891079 33854239 10330164 8867812 23602568 14681455 11433299 16431923 9716181 20587660 28137908 14701826 14536078 17361108 33854235 10827081 8662825 9472014 25852190 16223725 9192873 11940657 12839982 11132966 10359664 7799941 21092281 8647086 8756624 19631451 28514442 21372285 9660939 17431037 17254967 29439025 19470470 21241890 9840943 17970072 1388288 18559665 12800980 15004009 26186194 24358021 23853094 12529437 15557281
RBBP4 SUZ12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC73 LEO1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC73 CTR9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC73 PAF1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
LEO1 PAF1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CTR9 PAF1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EED SUZ12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CDK2 HIST1H1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK2 CDKN1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CTR9 LEO1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNE1 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
EED EZH2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PARP1 POLB â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10858306 11163244 11283614 11756412 11948190 12032095 12202749 12637553 14624239 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18087292 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 1974050 19748837 19772495 19847258 20027199 20064462 20211143 20227374 20478261 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22021614 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23414611 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 POLB â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10858306 11163244 11283614 11756412 11948190 12032095 12202749 12637553 14624239 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18087292 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 1974050 19748837 19772495 19847258 20027199 20064462 20211143 20227374 20478261 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22021614 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23414611 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
CDK7 CDK11B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16327805
PRKCD LIMK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15923181 16820362 22492986
PRKCB DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12958364 11940581 21386996 11313945 15567848
PRKCA DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12958364 11940581 21386996 11313945 15567848
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
CDK7 CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7533895 19847258 17386261 17884153 19667075 15703371 11959850 12648680 11900249 16697054 19809470
CDKN1B CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15583032 29997244 7478582 10022926 18692475 32814053 16189514
PRKCA ACO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15263083 15636585 17570479 16424901 8262977 15212693
CDK5 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 18833287 15178331 15917097 11877420 17085446 16554819 21947912 8131745 11517218 17459339 14970211 10341243 16705182 24610780 22112898 8764598 14557249 16223726 19455415 19090995 10936190 11146006 15944381
CDK2 BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
TAF1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10086334 22711989 11287574 9334328 9388200 17166848
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CDKN1B CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 8684460 26186194 9660939 17254966 15890360 16209941 12947099 12501191 26496610 9724724 9311993 9716181
CCNA2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 1833185 10924145 8423786
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
CCND2 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
EP300 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CDKN1B CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25910212 16189514
CCND2 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10477583 17517622 16713569
CCND2 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 17517622 27107012 11896535 10477583 9325318 31515488 16189514 32296183
CDKN1B CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 17145710 31831640 8978686 8684460 17293600 9632134 17254967 9311993 20837141 27175940 9488039 25241761 8891332 9660939 7753174 19470470 9218599 12529437 9192873 8756624 17254966 12501191 9891079 10393546 9716181 11940657
CDK2 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 17145710 16223725 21092281 15004009 10962581 9840943 8643455 24358021 8861947 21372285 17570479 11237742 10330164 22558078 10652300 19561641 10477583 18691976 23853094 12144826 10500095 1388288 10827081 17970072 28137908 19470470 8756624 10809788 14536078 15364936
CCNE1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 31831640 8978686 8684460 17293600 9632134 17254967 9311993 20837141 27175940 9488039 25241761 8891332 9660939 7753174 19470470 9218599 12529437 9192873 8756624 17254966 12501191 9891079 10393546 9716181 11940657
CDKN1B CCNE2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17254966 9840927 9858585 9840943
CCNE2 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17254966 9840927 9858585 9840943
CDK7 CDK1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
CDK7 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 85.0 1.0 Omnipath 16565220 18767875 11113184 33657372 27303922 19690332 19667075 15703371 10913154 14988404 1532335 29793495 20360007 7799941 19158392 19664995 33574676 19809470 8548828 7533895 17386261 34489572 26881937 17554681 20068231 18452278 21900495 18669648 12814430 16327805 18691976 15868411 8441405 21778139 25849598 27908669 12459251 1833185 19651622 22263797 19847258 19707596 17924679 20347419 29435156 18220336 34370741 19369195 22505032 21468563 17884153 12663041 22425727 7944411 12648680 11900249 8344251 16697054 31429764 24970150
CDK1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23455152 23543736 25032860 21490307 16492801 10931950
CDK1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 28.0 1.0 Omnipath 25841987 34381492 25691891 27941792 27653691 23549878 25800736 22187039 23241245 25038756 25334066 22964433 27716745 20935635 21131960 29576612 33593912 21123648 23438432 21659531 26552009
CDK1 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19107194 17570479 24011073 28756945
CDK1 UBA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19651622 20068231 7724583 19413330 7673335 18669648 9099746
CDK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 17081983 12058066 27253419 22285574 25908633 20333249 16912078 27553022 19933706 16083285 20068231 27619510 17570479 18669648 7213797 81161106 26536659 11278991 17287340 17924679 15190079 14670079
CDK7 CDK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
CDK7 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 18767875 11113184 25271736 7880532 19690332 19667075 15703371 14597612 20360007 21565702 19809470 15302935 8443411 7533895 10085115 15671017 17095507 10886368 17386261 20068231 18452278 9244189 8069918 11840777 1396589 17570665 16325401 16327805 25788262 11959850 15530371 11532001 19056339 9130709 14551212 17192257 19847258 22505032 17884153 20147522 12648680 11900249 16697054 93010995 8393783
CDK2 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 67.0 1.0 Omnipath 32076484 26123729 17081983 27998958 16565220 19007248 19367720 23840880 12058066 19690332 22285574 25922180 21272329 19413330 20333249 24282781 32092641 27553022 19933848 19933706 16083285 18318008 20068231 24998852 23627734 26993766 18165222 17535915 18669648 24290756 17942908 81161106 18691976 11278991 19561638 17287340 16376875 18243139 19651622 17924679 18220336 24282525 19369195 15190079 25531824 18212344
CDK2 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 125.0 1.0 Omnipath 26416244 20519948 19631451 16326706 17409098 15557281 9658399 23029392 22733130 17570479 26496610 23576547 12700233 9388487 10585280 27282251 27175940 15619620 25241761 15735731 9218599 9192873 17254966 15996662 9724724 11940657 18285702 22492278 23409140 18615582 12093740 22721951 15647383 9380407 17418410 16189514 17053782 17698606 25852190 10679394 17602833 9660939 12188931 15122251 10831586 25818643 22028818 21424700 12529437 15011833 12042314 11250701 11223033 23455922 8978686 16780593 21439954 15302935 19648963 14504289 9736735 10198259 16782892 11565035 21423803 16492801 9311993 12417722 17671428 21187893 15355997 28601655 10809788 10393546 15212693 10323868 26450989 23602568 18850315 12482975 9399644 15890360 9632134 17254967 26186194 20810788 20197382 15475007 12800980 17997402 12972555 15980415 24336329 26701207 25605247 26987798
CDK2 SF3B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15212693 12105215 17081983 30115685
CDK2 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20935635 25800736 29576612 23241245 32368395 29556394 17570479 27863310 26279746
CDK2 PELP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20807815
CDK4 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDKN1B CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 23602568 8978686 23707388 21439954 18850315 16326706 9658399 14597415 18615582 10198259 16782892 9632134 16189514 17053782 11360184 9311993 17092340 20837141 26186194 25241761 15695403 9464540 19470470 9106657 10908655 23543736 11940657 18285702
CDK7 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 7533895 14597415 19847258 8139570 12814430 17386261 16327805 16782892 28368408 17884153 19667075 15703371 14754892 12648680 11900249 12459251 16697054 19809470
CDK4 PELP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20807815
CDK5 PARP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 12556884 16332722 16858402 17303408 19151707 20724832 21727086 21922195 23589330 23850759
CDK7 CDK6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK6 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16160006 25241761 18615582 16782892 21439954 11360184
CDKN1B CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
RBBP4 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
SUZ12 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
EHMT2 DNMT3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19308066
PRKCD EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11020388 17434128 12379484 15006641 18053091 15212693 12590608
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
TAF1 GTF2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17081983 11278496 18452278
GZMA SET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19254476 19059912 11555662 16189514 9256474
PAK4 LIMK1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10461188 10559936 10613909 11018042 11340065 11413130 11950587 17522712 22154077
PAK4 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22154077 28007610 11413130 10559936 17522712 11018042 11950587 10613909 11340065 16641196 10461188
PRKCD PA2G4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17951246 16642037 25691158 21145366 17316401
PARP1 PARP3 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 14726013 15703371 16697054 17088286 17116881 18077224 19208614 19364882 196269035 19847258 20603072 21211721 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23178593 23562323 23568489 24050180 24210699 24684389 24976506
RAD54L HIST1H1A â—¼   KO_DOWN_REGULATES ✅ - -1.66 1.65 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
RAD54L RAD54L â—¼   KO_DOWN_REGULATES ✅ - -3.32 3.31 PKG 28854368
XPC HIST1H1A â—¼   KO_DOWN_REGULATES ✅ - -3.58 3.57 PKG 28854368
POLB HIST1H1A â—¼   KO_DOWN_REGULATES ✅ - -3.69 3.68 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368
SETX SETX â—¼   KO_DOWN_REGULATES ✅ - -8.56 8.55 PKG 28854368
SETX HIST1H1A â—¼   KO_DOWN_REGULATES ✅ - -10.52 10.51 PKG 28854368