YWHAZ
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
HSP90AA1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0908908106
19805354
|
KAT7
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5212855
10930412
|
KAT7
|
CDK11B
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5217777
15963510
|
ESR1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
3677090
|
PAK1
|
CDK11B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16413544
5218232
|
ATXN1
|
EIF3F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
EIF3F
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
CDK11B
|
EIF3F
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19245811
6948825
|
EIF3F
|
FBXO32
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6613251
18354498
|
PIN1
|
CSNK2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11940573
5215253
|
YWHAB
|
CSNK2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
LRRK2
|
NCBP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
RNPS1
|
YWHAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
ATXN1
|
YWHAE
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5216393
12757707
|
HSPA4
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
YWHAQ
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217174
15324660
|
HSPA8
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217040
15161933
|
ESR1
|
HSPA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11085516
|
POU2F1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18000219
20215511
|
ESR1
|
YWHAQ
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22329840
|
AR
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12069693
20610535
|
AR
|
VDR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15805579
16425262
|
AR
|
SPDEF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17483333
|
YWHAZ
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216393
12757707
|
ATXN1
|
YWHAZ
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5216393
12757707
|
URM1
|
CDK11B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
YWHAB
|
YWHAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
ESR1
|
YWHAB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
MYC
|
KAT7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
MYC
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.82
|
STRING
|
36370105
|
MYC
|
RRP1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
30415952
|
MYC
|
RNPS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
PAK1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16452229
12374744
|
LRRK2
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
ESR1
|
EIF3F
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
30573685
19805454
31527615
|
LRRK2
|
YWHAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
CDK8
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
29568061
|
ESR1
|
RRP1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21182205
31527615
|
ATXN1
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
12757707
5216393
|
YWHAZ
|
ATXN1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.84
|
0.84
|
mint
|
12757707
5216393
|
RPS27A
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
CCND3
|
VDR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16105657
21988832
|
ESR1
|
RARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9717844
25303530
25604459
|
LRRK2
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
18367605
22612223
20642453
26355680
16321986
23075850
|
EIF3F
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CDC37
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CDK7
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15461668
10949034
31527615
|
YWHAE
|
YWHAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
ESR1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
ESR1
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
YWHAB
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
YWHAG
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
YWHAB
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CSNK2A1
|
CSNK2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
AR
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
ESR1
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
CDC37
|
CDK7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8666233
33961781
29568061
26186194
|
RNPS1
|
DDX41
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
17353931
25920683
|
HSPA8
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
ATXN1
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
12757707
5216393
|
YWHAE
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
12757707
5216393
|
YWHAE
|
ATXN1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.89
|
0.89
|
mint
|
12757707
5216393
|
PIN1
|
ZBTB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
LRRK2
|
MSN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
MYC
|
HSP90AA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
28914785
12644583
|
MYC
|
PIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26655473
29467282
15048125
19131971
|
MYC
|
HSPA8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11983916
12695333
|
MYC
|
MSN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12695333
11085504
|
MYC
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
CDK11B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11983916
18414489
|
YWHAG
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17085597
15324660
|
YWHAB
|
YWHAG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17085597
15324660
|
YWHAE
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
RARA
|
CCND3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
16713569
12482873
|
CSNK2A1
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14675149
25862939
|
ESR1
|
VDR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15664452
17556531
12710998
|
AR
|
SF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9801462
11518799
17520059
|
HSP90AA1
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
LRRK2
|
YWHAQ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
YWHAZ
|
YWHAE
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
20618440
7899808
|
LRRK2
|
YWHAZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
HSPA4
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
HSP90AA1
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
HSP90AA1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
CDC37
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CSNK2A1
|
CDC37
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
26755559
18566753
20068231
15082798
18922470
19413330
12930845
27105117
|
CSNK2A2
|
CDC37
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20068231
15082798
19413330
12930845
|
CCND3
|
CDK7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
8139570
20107323
16782892
23622515
23737759
19487459
19075005
7954814
19458076
|
CDK7
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
10734072
24424504
25943391
21820033
21157430
28638477
|
CDK7
|
CDK11B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16327805
|
CDK7
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
30257348
10949034
15461668
9528769
22879364
12118371
28423697
27748765
15059947
16076840
7491495
12093745
23850489
15528270
7838153
|
CDK7
|
RARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
23637584
15670742
15249124
33902658
22135230
12054865
19917671
30532072
11955452
19078967
16713569
21297158
16769902
9230306
|
CSNK2A2
|
CSNK2A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
26186194
27705803
25519132
19011756
26496610
25852190
23455922
|
HSP90AA1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
1525041
19805354
20048054
15861399
17974989
26342197
17353003
26196320
16713569
27903893
1540595
21157430
19706771
|
KAT7
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10930412
16713569
|
MYC
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
MYC
|
PIN1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
ESR1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22396492
21835891
15073177
18193094
11517191
21505052
22892083
8707895
19569049
14722073
18414489
|
MYC
|
HSPA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1534087
14519204
1562593
10446203
|
PIN1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26655473
15048125
30723410
23716601
|
PAK1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
18521086
26944939
16778166
18755239
21893191
15178330
19205871
29548483
26554417
27003261
24505617
16452229
15193262
19557173
15642175
12374744
19465939
17604944
25447917
20179234
|
CDK11B
|
EIF3F
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
12446680
19245811
19854136
|
CDK11A
|
EIF3F
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12446680
19245811
|
YWHAE
|
YWHAB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20936779
17085597
12507503
24255178
17979178
|
YWHAB
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17085597
12657644
12426317
15071501
|
YWHAB
|
YWHAE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20936779
17085597
12507503
24255178
17979178
|
LRRK2
|
MSN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
17447891
9856983
20642453
20949042
21603132
25009464
19027715
24351927
19740074
23241358
20696313
24904275
19890007
22952686
8537411
15634677
9516463
18973807
26824392
27357661
24695735
19570025
|
YWHAE
|
YWHAG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21988832
20936779
17085597
12507503
17979178
|
YWHAG
|
YWHAE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21988832
20936779
17085597
12507503
17979178
|
YWHAG
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17085597
21827211
12426317
15324660
15071501
12657644
|
YWHAZ
|
YWHAE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
21988832
20936779
20618440
26496610
16376338
17979178
19766566
|
YWHAE
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
21988832
20936779
20618440
17085597
21827211
12426317
15071501
12657644
17979178
|
YWHAE
|
YWHAZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
21988832
20936779
20618440
26496610
16376338
17979178
19766566
|
CSNK2A1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11139588
26703694
9337862
20043841
11432835
11507039
9528769
7838153
|
CSNK2A1
|
VDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8384219
17368182
8622969
|
ESR1
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8300756
8912864
8732679
11038749
15831516
15870697
10076999
9626663
18414489
|
ESR1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8299561
11000528
22391641
|
AR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
12389206
11032808
16713569
11000528
18988627
|
ESR1
|
RARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
17641689
15831516
9717844
9841885
|
CDK11A
|
CDK11B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21078675
|
YWHAZ
|
YWHAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21827211
12657644
12426317
15071501
|