Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BCL6 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14654791 11914273
TP53 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16249378
BCL6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15577913
SMC1A BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11877377 5215162
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
SMAD3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19768112 15735739
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F1 CBX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
CDH1 CCND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0913813107 20439707
CCND1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
NCOA1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21163886 22542550
PRMT5 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK9 CDC37 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
GTF2F1 CDK9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17690249 22492511
E2F1 HMGA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22389255
E2F1 TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7734951
E2F1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20300951
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 CCNT1 â—¼   ACETYLATION ✅ 2.0 0.8 intact 7265510 19387490
TADA3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707411 16713569
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
POLR2C ERCC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
AR ERCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12593864 12648523
POLR2C GTF2H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
THRAP3 GTF2H3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGA1 GTF2H3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRKDC HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
CEBPB KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23456364 17301242
H3C2 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
KAT2B RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10747963
MYC GTF2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOTCH1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10644343 16847353
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
MYC HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20388374 19021144
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
STAT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10637230
H3C2 PARP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
PARP1 HIVEP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AR PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 20610535
PARP1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18314489
PARP1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
POLA1 PRIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
POLA1 PRIM2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
TOPBP1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19652550
H3C2 PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
RPA2 RIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 POLR2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RPA2 MED31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMARCA2 SMARCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10078207 16713569
STAT1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16195385
SMARCE1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18238828 19785031
SMARCA4 SMARCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10078207 16713569
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
SMARCC1 SMARCB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1459453 19785031
AR SMARCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603 20610535
SMARCC1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603 18581278
NCOA1 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15923603
SMARCC2 POLR2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMAD1 SMARCE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
XAB2 SNW1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SNW1 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213835 11278756
TADA3 TADA2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TAF9B DRAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TOPBP1 TOP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17006541 5219150
CEBPB TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8524227
TOPBP1 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086392 20871591
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
TP53 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21900401
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
TP53 TRRAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138177 11779500
TP53 MAML1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24473123 17317671
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
RBM4 HNRNPF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
STAT1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19646959
SMAD5 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNRNP70 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 CEBPB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12202226 5215691
CREBBP SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9679056 9679060
SMAD4 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9679056 9679060
SNRNP70 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD2 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD2 MED24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12167862 5215637
SNRNP70 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMURF1 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
HIVEP1 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 MED15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12167862 5215637
AR SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20739403 20610535
HIF1A NOTCH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18427106 0802047105
NOTCH1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18427106 0802047105
AR NOTCH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22347519 23145211
SMURF1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMURF1 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 17317136
ESR1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 19039095
HIF1A HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20010940 28602625
HES1 MAML1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22529374 21640102
RBPJ HES1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19866488 10520600
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
HIF1A CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17382325 5219810
CREBBP H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
MED4 CDK8 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 25281560
MED21 CDK8 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
MAML1 CDK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15546612
AURKA KIF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30576375 31881080
CEBPB SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22355693
SNRNP70 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 MED15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12167862 5215637
AR SMAD1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219486 17183365
CCNT1 CTDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
NCOA1 NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10612426 23547260
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
NCOA1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
ERBB2 SUPT6H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
KRAS ERBB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
THRA ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11578528 11687272
TFCP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21655924 19966177
ESR1 GTF2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9841876 16651265
ESR1 MTA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15169784
AR ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11371645 20610535
AR KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8423674 24172884
AR MBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 7657701
TBP GTF2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7521915 16330756
AQR RBM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
AQR WDR77 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
POLR2C GTF2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
GTF2F1 GTF2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218897 16878124
SNRNP70 PRMT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PRMT5 CTDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15670829 5217489
POLR2C GTF2F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
POLR2A CTDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216783 14576432
SMAD5 SNRNP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
POLR2C MED17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
POLR2C POLR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
POLR2C MED27 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
RBM4 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
THRA MED17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14576168 5216777
MED8 MED11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MED4 MED19 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 25281560
MED4 MED19 â—¼   PROXIMITY ✅ 0.8 0.8 mint 25281560
THRA MED29 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14576168 5216777
RBPJ MAML3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17284587 11101851
RBPJ MAML3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21873209 12370315
THRA MED8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14576168 5216777
H3C2 SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
RBPJ MAML2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17284587 11101851
RBPJ MAML2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21873209 12370315
MED12 MED15 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
CCNH POLR2C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GTF2H3 TCEA1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
MED27 MED29 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CCNT1 MYC â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
PPM1K BCKDHA â—¼   DEPHOSPHORYLATION ✅ + 0.8 0.8 Signor 19411760
CCNH TCEA1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
BRCA1 SMAD3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19768112 15735739
EP300 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18280497 16204234 19622798 12960163 24636898 33742100
MED6 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16204234 15808511
MED12 MED24 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CDK19 MED15 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
MED12 MED9 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CDK7 POLR2C â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
GTF2H3 TBP â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
SMARCB1 ACTL6A â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
HDGF CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21907836 34079125
MYC CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CBX5 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 20562864
CBX5 WIZ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 20562864
CDC37 ERBB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25036637 24189400
CTR9 CDK9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26496610
EP300 SMAD5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16516194 16613856
GTF2B GTF2H3 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
GTF2H3 POLR2A â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
SMAD2 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22995475 15009097 11058129 34576109
SMAD3 KAT2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22995475 15009097 11058129 15994459
MYC SMC1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC SMC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC PRKDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RIF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
ERBB2 RPA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21555369 26496610
ESR1 SNW1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19934264 33731348
SNW1 CCNT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20467437 19818711
CDC16 BUB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CDC16 MED12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR1 AURKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21761334 31527615
MED25 MED13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14657022 29568061
MED13 MED31 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 29568061
MED13 MED11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 29568061
ESR2 SEC13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29509190 25604459
CTR9 CCNT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26659056 26496610
ESR1 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ESR1 RBM33 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
RBM4 BUD13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MED7 MED26 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
MED6 MED16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED15 MED27 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED15 MED11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED15 MED8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED30 MED11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED11 MED27 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED26 CCNC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 21729782
MED4 MED9 â—¼   PROXIMITY ✅ 0.82 0.82 mint 25281560
MED23 MED27 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25281560
MED27 MED16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED30 MED16 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 15989967
MED25 MED22 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 14638676
MED23 MED8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25281560
TADA3 TP53 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
CCNC MED15 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HIST2H3C TP53BP1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
MED1 MED31 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
MED15 MED29 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
CDK19 MED21 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
CDK8 MED12L â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
MED20 MED6 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
PAF1 SUPT6H â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
MED20 MED8 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
BRCA1 CDK9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22990118 28278048
CBX3 WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 33022573 27705803
SNW1 CDK9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20467437 19818711 26209609
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
MYC ERCC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33381997 17314511 29467282
WDR5 KAT2B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18838386 28514442 26186194 33961781
SNW1 MYC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30415952 19818711 29467282
MYC CTR9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 29467282 26687678
RPA2 ESR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11953755 31527615
SNW1 AQR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20467437 28502770 33961781
TADA3 TAF6L â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
TADA3 TRRAP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 33961781 24981860 26186194
TADA3 TAF9B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
TAF6L TRRAP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
MED15 SMAD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12167862 27703004
CREBBP HIST2H3C â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
CDK8 CTDP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19914168 26496610
MED7 MED12 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 33961781 24981860 26186194
MED12 MED25 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 20133760 26496610 33961781
MED12 MED31 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 20133760 26496610 24981860
MED12 MED15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26496610 24981860 33961781 14657022 20133760
MED6 SMAD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12167862 27703004
MED15 MED13 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 29568061 24981860
MED13 MED22 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 29568061 24981860
MED13 MED20 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 29568061 24981860
CTR9 ELOB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31253590 24981860 26496610
MED1 CCNC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 18391015 20098423 33961781 24981860 26186194 20133760
MED21 MED31 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
MED23 MED31 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 25281560 24981860
MED28 MED31 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760 24981860
MED21 MED10 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
MED20 MED10 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 25281560
MED14 MED7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 9989412 33961781 24981860 26186194
MED15 MED7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860 26186194 14657022
MED7 MED16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
MED7 MED20 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
MED7 MED18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
MED7 MED23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
MED7 MED30 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
MED7 MED11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
MED7 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
MED7 MED27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
MED7 MED17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 24981860
MED11 MED14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 24981860 26344197
MED25 MED14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 24882805 25792360
MED28 MED14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760 24981860
MED14 MED27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 24981860 9989412 26344197
MED14 MED17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9989412 18418385 33961781 24981860 22939629 26344197
MED14 MED8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 24981860 26344197
MED6 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
UBL4A GET4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 23246001 19615732
MED21 MED15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
MED28 MED15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760 24981860
MED15 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
MED15 MED23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 25281560 33961781 24981860
MED15 MED17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 24981860 26344197 33961781
MED25 MED17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 14638676 33961781
MED17 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197 24981860
MED17 MED16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
MED28 MED11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 24882805 33961781 24981860 20133760
MED11 MED16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 24981860 26344197
MED11 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197 24981860
MED28 CCNC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 15175163 33961781 24981860 26186194 20133760
CCNC MED23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860 26186194 25281560
MED21 MED27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
MED24 MED27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
MED25 MED16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 24882805 25792360
MED28 MED16 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760 24981860
MED16 MED8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 24981860 26344197
MED25 MED18 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 14638676
MED18 MED30 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 20133760 24981860
MED18 MED22 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 24882805 33961781 24981860 20133760
MED28 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760 24981860
MED30 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 15989967 24981860
MED22 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 24981860
MED24 MED8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197 24981860
MED30 MED23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 25281560 18691967
MED28 MED23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760
MED28 MED25 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760
CBX5 EHMT2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CBX3 HIST2H3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST2H3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
MED12L MED13 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CCNC MED16 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CTR9 SUPT6H â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NOTCH1 SNW1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MED25 MED6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MED16 MED27 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HIST2H3C WDR5 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
PARP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 25252691 26831064
PRKDC BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10608806 25223785
CDK8 CDC37 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 29568061
CDK9 TP53 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
E2F1 NRIP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20410059 22629304
MYC HIF1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 15071503 28205554
PRKDC PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16794079 9398855 21575865 20085707
PRMT5 SMARCE1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
TAF9B TRRAP â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
MED23 CDK8 â—¼   PROXIMITY ✅ 0.84 0.84 mint 25281560
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 17627277 5222291
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
ESR1 MED17 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 11867769
ESR1 BUD13 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
ESR1 MED4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
ESR1 MED27 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 EHMT2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21984853 31527615
PAF1 CTR9 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
MED10 POLR2C â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
TCEA1 PAF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20178742 21596312
MED18 MED31 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 14638676 14576168 33961781 24981860 20133760
MED4 MED10 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 25281560
MED4 MED10 â—¼   PROXIMITY ✅ 0.84 0.84 mint 25281560
MED8 MED7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 12584197 33961781 24981860 26186194
MED8 MED6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24981860 12584197 26344197
MED23 MED17 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 25281560
MED8 MED17 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14576168 33961781 26344197 24981860
MED17 MED30 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 12584197 15989967 24981860
MED8 MED27 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24882805 24981860 12584197 26344197
MED23 MED20 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 25281560
MED28 MED8 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15175163 12584197 24882805 33961781 24981860 20133760
AR CCND1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
TOP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HIF1A KAT2B â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
POLR2A SMARCB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CDK8 MED26 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
MED30 MED6 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MED17 MED20 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
MED31 POLR2C â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
KAT2B SMAD3 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
GTF2F1 GTF2H1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
TADA3 WDR5 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
MED13 MED27 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
NIPBL CBX3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 15882967 20850016 28167679
H3C2 CBX5 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 20871592 8087215
CBX5 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 16415788 5218238
H3C2 CBX5 â—¼   PROXIMITY ✅ 0.85 0.85 mint 25281560
CDK7 E2F1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10428966 23397142 20106982
EP300 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
EP300 SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10205054 20851880 22365546 16613856 10673036
TOP1 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28415827 15848144
SMARCD1 SMARCC1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591612
SMAD2 ESR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20207742 11555647
SMAD3 CEBPB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12202226 12524424
MED12 CDK19 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 30099503
MED12 MED20 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26496610 20133760 33961781 24981860 27684187 25281560
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
NCOA1 TBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8754792 16713569
MED4 MED31 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 25281560 24981860
MED7 MED10 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
MED7 MED4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 24981860 26186194 25281560
MED20 MED14 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 25281560 26344197 24981860
MED6 MED14 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24981860 9734358 26344197
MED15 MED20 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
MED20 MED15 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 25281560 26344197 24981860
MED15 MED4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 25281560 26344197 24981860
MED20 MED11 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 25281560 26344197 24981860
MED20 MED21 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 25281560 24981860
MED16 MED4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED20 MED24 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 25281560 26344197 24981860
MED20 MED22 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 25281560 26344197 24981860
MED11 MED20 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
MED12 MED17 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
SMAD4 SMAD5 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CEBPB EP300 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MED13 MED8 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
CDK19 MED12L â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
NRIP1 THRA â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
MED11 MED27 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CCNC MED17 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
AURKA BRCA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22110403 14990569 26831064
CBX3 ZMYM4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 27705803
CBX5 EHMT2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24981860 17962312 20562864 15200951
CBX5 NIPBL â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15882967 20562864
KAT2B CCND1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11328859 10318892
ESR1 CCNH â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12527756 31527615
SMAD4 EP300 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 25514493 18215124 9843571 14612423 10887155 22033265
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
HIST2H3C KAT2B â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
KAT2B HIF1A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22908229 21148070 20620956 16543236
MYC TBP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 15723054 8755740
PPM1G PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 27880917
ESR1 STAT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25303530 31527615
ESR1 CCNT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15940264 31527615
CDK19 MED11 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15175163 33961781 24981860 23602568
CDK19 MED30 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568
CDK19 MED28 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 20133760
CDK19 MED21 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 15175163 33961781 24981860 23602568
MED9 MED25 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15175163 14638676
MED11 MED30 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
CCNC MED12L â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
PAF1 POLR2C â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
GTF2H1 POLR2C â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
MED15 MED27 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
MED15 MED8 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
TAF6L TRRAP â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
MED6 POLR2C â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
MED13 MED6 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CBX3 WIZ â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 27705803
TCEA1 CDK7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26186194 9305922
CDK9 PAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26659056 24837678 21873227
KAT2B E2F1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24502362 23001041 35140242 19188449 24112038 15123636
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
EP300 NCOA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16713569 10973497 20368990 15688032 14722092 12208951 11113179
KAT2B TAF6L â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 9885574 31753913 33961781 9674425 24981860
KAT2B TADA3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 9885574 31753913 10373431 33961781 9674425 26186194 18089809 24981860
MYC MED12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12660246 29467282
MYC TOP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 20195357 30415952 29467282
MYC WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 27320920 35140242 29467282 31767764 30415952
HDGF PARP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21907836 34079125
PPM1G USP7 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
WDR5 TADA3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 18838386 33961781 24981860 26186194
TAF6L TAF9B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956 33961781 24981860
SMAD5 SMAD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10531362 16516194 16189514 15231748
CDK8 MTBP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30695077 29568061 26496610
ESR2 MED12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21182203 11867769
MED12 MED17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 20133760 26344197
MED12 MED6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 27684187 22939629 20133760 26344197
MED12 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 27684187 22939629 20133760 26344197
MED12 MED14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18418385 26496610 23563140 33961781 24981860 27684187 20133760 26344197
MED12 CCNC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 30099503 33961781 24981860 26186194 19047373 20133760
MED12 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 22939629 20133760
MED12 MED11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 22939629 20133760
MED12 MED21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26496610 33961781 24981860 22939629 20133760
MED12 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 22939629 20133760 26344197
MED13 MED17 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
MED17 MED13 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 29568061 26344197 24981860
MED26 MED13 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24981860 21729782 23563140
MED30 MED13 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 29568061 15989967
CDK19 MED13 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033 23746844
MED13 MED8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 29568061 26344197
MED13 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 29568061 26344197
MED13 MED14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18418385 24981860 22939629 29568061 26344197
MED13 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 29568061 26344197
MED13 MED6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 29568061 26344197
MED13 MED7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23563140 33961781 24981860 26186194 29568061
MED13 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 22939629 29568061 26344197
MED13 MED23 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12421765 29568061 33961781 24981860 25281560
ESR1 MTA3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18451880 31527615
ESR1 MED25 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24960263 17641689 31527615
MED1 MED22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15989967 20098423 33961781 24981860 20133760
MED1 MED31 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 15989967 24981860
MED1 MED7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 18391015 15989967 24882805 33961781 24981860 26186194
ESR2 MED6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29509190 11867769
ESR2 MED20 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29509190 11867769
CDK19 MED31 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033
MED7 MED31 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 20211142 33961781 24981860 26186194
MED26 MED31 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24981860 21729782
MED29 MED7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194
MED26 MED7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 24882805 33961781 24981860 26186194 21729782
MED19 MED7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 24882805 14576168 33961781 24981860 21729782 26186194
CDK19 MED7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033
MED28 MED7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194
MED18 MED14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 22939629 20133760 26344197
CDK19 MED14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033
MED26 MED14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24981860 9989412 21729782
MED15 MED14 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18418385 24882805 24981860 14657022 26344197
MED14 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9989412 18418385 24882805 33961781 24981860 22939629 26344197
MED14 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18418385 24882805 24981860 22939629 26344197
MED26 MED6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24981860 21729782
MED18 MED6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24882805 33961781 24981860 20133760 26344197
MED6 MED23 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10993082 33961781 25281560
MED6 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26344197 24981860 24882805
MED6 MED15 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14983011 14657022 26344197 24981860
MED19 MED15 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194 21729782
MED26 MED15 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 14657022 21729782 24981860
MED18 MED15 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 20133760 26344197
CDK19 MED15 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 33961781 24981860 23749998 26186194 23602568 32707033
MED9 MED15 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24981860 27684187
MED15 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26344197 14657022 24882805 24981860
MED27 MED17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26344197 33961781 24882805 24981860
MED26 MED17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 33961781 21729782 24981860
CDK19 MED17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 23749998 26186194 23602568 32707033
MED9 MED17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 14638676 33961781 24981860 27684187
MED26 MED11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24981860 21729782
MED11 MED21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 24981860
MED11 MED18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 22939629 26344197
MED26 CDK19 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24981860 21729782 23746844
MED19 CDK19 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 23563140 33961781 24981860 26186194 21729782 32707033
CDK19 MED22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033
CDK19 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033
CDK19 MED4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033
CDK19 MED20 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033
CDK19 MED23 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033
MED19 CCNC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 23563140 33961781 24981860 26186194 21729782
MED29 CCNC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 26186194
MED16 MED21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 24981860
MED26 MED21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 24882805 33961781 24981860 21729782
MED19 MED21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 14576168 33961781 24981860 21729782 26186194
MED23 MED21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 25281560 24981860
MED9 MED21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 14638676 24882805 33961781 24981860 27684187
MED21 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 24981860
MED21 MED22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 24981860
MED21 MED8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22939629 33961781 24981860
MED28 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24882805 33961781 24981860 20133760
MED26 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24981860 21729782
MED18 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 20133760 26344197
MED29 MED26 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 33961781 21729782 24981860
MED29 MED28 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24882805 33961781 24981860 20133760
MED29 MED22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 14638676 24882805 33961781 24981860
MED29 MED30 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 33961781 24882805 24981860
MED26 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24981860 21729782
MED18 MED16 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 22939629 20133760 26344197
MED16 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24882805 24981860 33961781 22939629 26344197
MED19 MED22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 14638676 14576168 33961781 24981860 26186194
MED19 MED26 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 24882805 23563140 14576168 33961781 24981860 21729782 26186194
MED19 MED28 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 24882805 33961781 24981860 26186194 21729782 20133760
MED19 MED30 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 14576168 33961781 24981860 21729782 26186194
MED28 MED18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 20133760
MED26 MED18 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15175163 33961781 24981860 21729782 20133760
MED18 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 22939629 20133760 26344197
MED18 MED8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 22939629 20133760 26344197
MED26 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 33961781 24981860
MED25 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26344197 25792360 24882805 33961781
MED28 MED22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24882805 33961781 24981860 20133760
MED26 MED22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 33961781 24981860
MED23 MED22 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 25281560 26344197
MED26 MED23 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 33961781 21729782
MED26 MED25 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 14657022 21729782
MED26 MED30 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24981860 21729782
MED9 MED20 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 14638676 33961781 24981860 27684187
MED26 MED20 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 33961781 21729782 24981860
MED28 MED26 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 33961781 24981860 21729782 20133760
CBX3 CBX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GTF3C1 GTF3C3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK8 MED22 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK8 MED19 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK8 MED28 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED12 MED29 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED12 MED4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED12 MED27 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED12 MED18 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED10 MED13 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED13 MED24 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED1 MED6 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED1 MED25 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED1 MED27 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CCNC MED10 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED10 MED24 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED19 MED7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED11 MED19 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK19 MED28 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK19 MED24 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK19 MED9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED19 MED21 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED21 MED29 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED21 MED28 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED19 MED30 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED19 MED24 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED19 MED25 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED18 MED24 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BRCA1 CREBBP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDK19 CDK8 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED12 MED16 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED12 MED6 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED13 MED29 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED1 MED20 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED1 MED7 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED1 MED9 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED7 MED9 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED11 MED21 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDK19 MED19 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CCNC MED19 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CCNC MED18 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED18 MED21 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED24 MED29 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED19 MED9 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED19 MED26 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED19 MED23 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED19 MED22 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED19 MED28 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EP300 STAT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ERCC3 TCEA1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED11 MED12 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED12 MED21 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED1 MED30 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED1 MED21 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK19 MED10 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK19 MED22 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CCNC MED28 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED21 MED8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED13L MED19 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED24 MED8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDK7 E2F1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDK8 MED20 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED12 MED30 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED10 MED25 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED14 MED29 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED17 MED29 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED11 MED18 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED11 MED24 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED21 MED9 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED16 MED24 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 TOPBP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED13 MED18 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CTR9 WDR61 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CCNC MED1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED19 MED31 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED10 MED13L â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED28 MED7 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED22 MED7 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED14 MED8 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED27 MED6 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED15 MED18 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CDK19 MED17 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED17 MED27 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED21 MED22 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED18 MED27 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED13L MED18 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED18 MED26 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
GTF2H1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK8 MED18 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED10 MED23 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED10 MED9 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED14 MED4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED14 MED15 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK19 MED6 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED15 MED19 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED17 MED8 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED11 MED4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK19 MED20 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK19 MED18 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDK7 TCEA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED12 MED7 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED1 MED11 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED12L MED7 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED14 MED16 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED14 MED27 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED4 MED9 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED18 MED9 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED18 MED23 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED18 MED22 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED13 MED21 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MED1 MED28 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MED1 MED22 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MED15 MED7 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MED11 MED14 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MED17 MED6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CCNC MED8 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MED21 MED24 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MED22 MED4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
E2F1 TOPBP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMARCA2 SMARCA4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BCKDHA PPM1K â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MED10 MED28 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CCNC MED6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MED24 MED4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MED16 MED8 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMC1A BRCA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11877377 25184681 16713569 26831064
BRCA1 MED17 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12154023 11504724 15208681
BRCA1 CBX3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 23074186 25634209 25184681
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
CDK9 CDC37 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32707033 25036637 24189400 33961781 20305087 26186194 24981860 27684187 23455922
CDK7 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15461668 10949034 31527615
MYC CDK9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12944920 19818711 26687678 11673469 17700062 30415952
TRRAP E2F1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9708738 18542057 11418595
EP300 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11371641 21988832 10199400 12237408 11264182 15623506
KAT2B WDR5 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
TADA3 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12034840 31527615 18089809 20413580
SMAD2 SMAD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9111321 28628118 18729074 28205554
RBPJ NOTCH1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8176976 21475249
CDK8 MED27 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CDK8 MED25 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MED8 MED12 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12584197 26496610 33961781 24981860 27684187 22939629 20133760 26344197
MED9 MED12 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 14638676 26496610 24981860 27684187
ESR1 MED13 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11867769 31527615
CTR9 WDR61 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22451921 20178742 26496610 16024656 33961781 20305087 24981860 26344197
TCEA1 TBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20562857 10454562 9305922
MED1 MED15 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MED1 MED8 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MED9 MED1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15175163 14638676 24882805 20098423 33961781 24981860 27684187
ESR2 NRIP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11500849 21182203 15604093
RBPJ MAML1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8176976 21475249
ESR2 MED23 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29509190 21182203 11867769
ESR2 MED16 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29509190 21182203 11867769
ESR2 MED14 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29509190 21182203 11867769
ESR2 MED24 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29509190 21182203 11867769
MED31 POLR2A â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MED9 MED31 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 24981860 14638676
MED10 CDK19 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568
MED9 MED7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15175163 14638676 33961781 24981860 26186194
MED9 MED14 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 24981860 14638676 27684187
MED21 MED14 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 9734358 33961781 24981860 22939629
MED14 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED9 MED6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 24981860 14638676 27684187
MED25 MED6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14983011 14657022 17641689 25792360
MED4 MED6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED25 MED15 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14983011 14657022 24882805
MED11 MED8 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MED11 MED9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 24981860 14638676
CDK19 MED16 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CDK19 MED8 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
CDK19 MED18 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15175163 33961781 24981860 23602568 22939629
MED22 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED28 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 20133760 33961781 24981860 25281560
MED27 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED24 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED20 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 25281560 26344197 24981860
MED4 MED8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED4 MED23 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25281560 33961781 21293490
MED20 MED27 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24882805 33961781 24981860 25281560 26344197
MED9 MED27 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 24981860 14638676
MED9 MED29 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 33961781 14638676 24981860
MED23 MED16 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 25281560 24882805 24981860
MED19 MED9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15175163 14638676 33961781 24981860 26186194 21729782
MED18 MED9 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 15175163 14638676 33961781 24981860 27684187
MED23 MED24 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 25281560 26344197
MED9 MED24 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 33961781 14638676 24981860
MED9 MED22 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 14638676 33961781 24981860 27684187
MED9 MED30 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 24981860 14638676
MED30 MED20 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15989967 24882805 33961781 24981860 25281560
MED30 MED8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24981860 12584197 24882805
MED9 MED28 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 14638676 33961781 24981860 20133760
MED9 MED26 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 14638676 24981860 21729782 27684187
MED9 MED8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 24981860 14638676 27684187
TBP TP53 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CDK8 MED9 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MED12 MED8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MED1 MED17 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
EHMT2 WIZ â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MED19 MED20 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MED1 THRA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MED1 MED16 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MED10 MED15 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MED14 MED24 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CDK19 MED27 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
GTF2F1 GTF2H3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MED1 MED24 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MED30 MED7 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ESR1 MED1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MED29 MED7 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MED7 MED8 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MED17 MED18 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MED16 MED18 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
SUPT16H SUPT6H â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MED4 MED7 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CREBBP KAT2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MED10 MED8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MED27 MED7 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREBBP SMAD3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MED19 MED6 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MED4 MED8 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MED1 MED12 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED1 MED23 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED1 MED4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED10 POLR2A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED15 SREBF1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED11 MED16 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MYC TRRAP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CREBBP SMAD2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CDK8 MED16 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CDK8 MED29 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CDK8 MED30 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MED12 MED14 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ESR1 NRIP1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MED10 MED16 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MED17 MED24 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CDK19 MED30 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CCND1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17334399 16713569 9244350
MED1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15208681 16713569
STAT1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10792030 16713569
CDC37 CDK7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8666233 33961781 29568061 26186194
PARP1 E2F1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20133863 14627987
KAT2B EP300 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8684459 12888487 9267036 12419806 21413932 22384255 20870727 33051058
KAT2B NCOA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9445475 9296499 9223281
SMAD3 SNW1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11278756 18729074
SNW1 SMAD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11278756 18729074
TRRAP ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31527615 11931763 16260778 12738788 12837248
SMAD4 CEBPB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12202226 16959612 12524424
HIF1A SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 28471448 11486006 14741200
MED19 CDK8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 23563140 33961781 24981860 26186194 21729782 32707033 29568061
MED30 CDK8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26496610 18691967 33961781 24981860 26186194 23602568 29568061
CDK8 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 29568061 26496610 33961781 24981860 26186194 23602568 32707033 25281560
CDK8 MED27 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26496610 33961781 24981860 26186194 23602568 29568061
CDK8 MED22 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26496610 20098423 33961781 24981860 26186194 23602568 29568061
CDK8 MED18 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26496610 33961781 24981860 23602568 29568061
CDK8 MED11 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24981860 29568061 26496610 23602568
MED13 MED12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 29568061 26496610 33961781 24981860 27684187 20133760 26344197
MED30 MED12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15989967 30099503 26496610 33961781 24981860 18691967 20133760
MED28 MED12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 15989967 33961781 24981860 20133760
MED19 MED12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 23563140 14576168 33961781 24981860 21729782 26186194 26344197
MED26 MED12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 24981860 21729782 23563140
MED12 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30099503 26496610 20133760 33961781 25281560
MED9 MED13 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 14638676 24981860 27684187 29568061
MED4 MED13 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12421765 29568061 33961781 24981860 22939629 25281560
MED13 MED21 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 24981860 22939629 29568061
NCOA1 ESR2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11500849 10809226 11376110 14715875 11014206 10731636 15604093 19126643 12554772
TBP ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9259327 16713569 31527615 11595744
ESR1 MED20 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
ESR1 CCNC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
ESR1 MED16 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
ESR1 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
ESR1 MED6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
MED26 MED1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 20098423 33961781 24981860 21729782
CDK19 MED1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033 22939629 20133760
MED8 MED1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 12584197 15989967 33961781 24981860 22939629 20133760 26344197
MED25 MED1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 14638676 15989967 17641689 20098423 25792360 33961781 14983011 14657022 20133760
MED1 MED30 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15989967 33961781 24981860 18691967 20133760
MED1 MED11 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15989967 33961781 24981860 22939629
MED1 MED21 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15989967 24882805 33961781 24981860 22939629
MED1 MED27 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15989967 33961781 24981860 22939629 20133760 26344197
ESR2 MED17 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29509190 21182203 11867769
PAF1 WDR61 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22451921 19410543 20178742 16024656 33961781 20305087 24981860 26344197
CDK19 MED31 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MED29 MED31 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 14576168 33961781 24981860
MED10 MED29 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MED10 MED9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 14638676 24882805 33961781 24981860 27684187
MED10 MED24 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 15989967 17404243 24882805 14576168 33961781 24981860 10882111
MED10 MED26 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 17404243 24882805 14576168 33961781 24981860 21729782
MED10 MED28 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 24882805 33961781 24981860 20133760
MED10 MED30 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860
MED22 MED7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 12584197 33961781 24981860 26186194
MED7 MED21 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24882805 33961781 24981860 26186194
MED29 MED14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 14576168 33961781 24981860 22939629 26344197
MED19 MED14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 14576168 33961781 24981860 21729782 26186194 26344197
MED14 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9989412 18418385 24882805 33961781 25281560 26344197
MED30 MED6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24981860 12584197 15989967 18691967
MED11 MED6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 24981860 26344197
CDK19 MED6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033 26344197
MED6 CCNC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10993082 33961781 24981860 26186194
WIZ EHMT2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16702210 26028330 27705803 26496610 21258344 24981860 28698370
MED29 MED15 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 33961781 26344197 24981860
MED17 MED28 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MED11 MED17 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 26344197 24981860
MED19 MED11 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 14638676 14576168 33961781 24981860 21729782 26186194
MED11 MED8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12584197 24981860 30021884 22939629 26344197
MED29 CDK19 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033
CDK19 MED8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033 26344197
CDK19 MED24 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033 26344197
CDK19 CCNC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 30695077 25344755 23602568 33961781 24981860 26186194 19047373 32707033 23746844
CDK19 MED16 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033 22939629
MED21 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24882805 33961781 24981860 22939629 25281560
MED30 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 25281560 12584197 24981860
MED26 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 24882805 33961781 24981860 21729782 25281560
MED25 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 25281560 14638676
MED4 MED18 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 18250152 20133760 33961781 24981860 22939629 25281560 26344197
MED29 MED27 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 33961781 26344197 24981860
MED27 MED22 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 12584197 24882805 24981860
MED27 MED30 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24882805 24981860 12584197 26344197
MED16 MED29 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MED29 MED24 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 33961781 24981860 22939629 26344197
MED29 MED25 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 33961781 14638676
MED29 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 33961781 25281560
MED29 MED16 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 33961781 24981860 22939629 26344197
MED19 MED16 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 14576168 33961781 24981860 21729782 26186194 26344197
MED9 MED16 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 22939629 24981860 14638676
MED19 MED24 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 14576168 33961781 24981860 26186194 26344197
MED19 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 14576168 33961781 21729782 26186194 25281560
MED19 MED25 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15175163 14638676 23563140 14576168 33961781 21729782 26186194
MED18 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 20133760 33961781 25281560 26344197
MED30 MED22 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 12584197 24882805 24981860
MED23 MED25 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MED9 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 25281560 14638676
MED25 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24882805 25792360 33961781 14657022 25281560 26344197
MED28 MED20 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 15989967 20133760 33961781 24981860 25281560
MED20 MED8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12584197 33961781 24981860 25281560 26344197
MED8 MED26 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 24981860 21729782
MED1 MED10 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CCNC MED7 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MED23 MED7 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MED20 MED29 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MED12 MED19 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
MED18 MED31 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CDK19 MED29 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
MED18 MED20 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
PRKDC RPA2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CREBBP GTF2B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
MED1 MED26 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
MED17 MED21 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
MED18 MED29 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
MED16 MED19 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDK8 MED4 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDK8 MED17 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED13 MED16 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED10 MED27 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED10 MED30 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED14 MED17 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED15 MED16 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDK19 MED4 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED29 MED4 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MED10 MED26 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MED16 MED4 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
NCOA1 THRA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
POLR2C SUPT6H â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
MED14 MED19 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
MED28 MED6 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
SMAD5 SMURF1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MED10 MED12 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
AR NCOA1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MED19 MED4 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CDK8 MED10 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED13 MED19 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED1 MED29 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED1 MED14 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED1 MED18 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED10 MED19 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED10 MED22 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED14 MED18 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED29 MED6 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED17 MED19 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED19 MED27 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED19 MED29 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED18 MED19 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED18 MED8 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CDK19 MED1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MED18 MED6 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MED21 MED4 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MED27 MED4 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MED18 MED4 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
STAT1 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19122651 15596057
TP53 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23852341 19427386
EP300 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17828269 12402037
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
EP300 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 19887647 10655477 11782371 16713569 21212407 22787115
MYC BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12646176 11916966 16713569 20215511 9788437 30415952 14612409
CBX5 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314413 11336697 16713569 20850016 27705803 20231385 33961781 21888893 24981860 15306854 34079125 20562864 19498464
EHMT2 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27705803 22514736 33961781 24981860 15200951 34079125 17962312
MYC CBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
E2F1 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12629508
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CCND1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16061635 9039267 11073968
CEBPB CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22242598 11162569 12810706
CCNH ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 33707221 17643375 15220921 33453189 8692842 33961781 26186194 19934020 9118947 26340423 10734143
KRAS CDC37 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
CDK7 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 8692841 17643375 15220921 8521393 33453189 33961781 10082552 9130708 23602568 28977422 32707033 29568061 26340423
HES1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15467735 19891787
E2F1 POLA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18347061 7929342
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
E2F1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15014447 11491305
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
E2F1 RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11313881
MAML1 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15546612 12050117 12391150
EP300 CEBPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28428115 9343424 14630807 12471036
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
GTF2H3 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9118947 8652557 10734072
MYC KAT2B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15572685 35140242 12660246
NCOA1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12163591 10809234 10777539
KAT2B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34811519 16096646
CCNT1 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12944920 19818711 11673469 17700062 29467282 30415952
SMAD2 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11804592 28628118 28205554
TRRAP MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11839798 19818711 9708738 17314511 17353931 10611234 16705173 11511539 32140074 21150319 35140242 12660246 29467282 30415952 12077335 20946988
SMAD1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 15576399 22290435 22761862
CEBPB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21098707 20581311 16585579
RBPJ MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18490439 10644343 16847353
MYC PRKDC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC THRAP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 12808131
MYC AQR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CDK11B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 18414489
MYC TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NOTCH1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
TOP1 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 15247263 15848144
SMARCC1 SMARCB1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24421395
SMARCC1 SMARCE1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 20829358
AR SMC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22695118 23417242 16637073
TP53 RBPJ â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 19836055 24254977 26302407
TP53 RBPJ â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 19836055 24254977 26302407
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
TP53 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15383401 20332115 21478913
HSPA1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
TP53 HSPA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
STAT1 MED16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
SMAD2 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 25514493 11927552 28443643 21988832 20211142 15467747 12732634 25609649 15922743 12419246 9288972 21454478 19139564 24157709 18729074 22442258 17283070 16916642 15350224 17591701 11274206 15761153 31591477 26555259 9892009 9311995 10085121 9389648 10781087 12167862 10878024 18783722 27703004 18511908 28468752 19135894 10531362 12794086 15231748 21297662 12621041 19917253 11027280 24584437 16751102 31932471 10199400 21532621 12808092 33961781 11264182 11102446 11114293 12543979 23788427 15817471
SMAD1 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 17183365 16189514 32296183 31467278 12167862 14701756 12874272 28468752 15761153 24412244 10531362 15231748 11700304 11779505 26555259 9436979 21454478
SMAD3 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 16189514 25514493 11927552 28443643 21988832 20211142 15084259 12732634 19768112 15467747 20142324 25609649 15922743 12917407 12419246 20564330 24382352 19139564 32296183 24157709 18729074 22442258 10092624 17283070 15350224 17591701 15761153 31591477 10995777 26555259 9892009 9311995 15588252 12167862 10878024 25910212 27703004 33990575 28115363 18055455 22310290 19135894 10531362 12794086 15231748 21297662 22045334 19917253 24584437 27107012 29892012 29997244 21532621 27845895 21597466 25502805 11114293 12543979 23788427
SMAD4 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22775504 17452626 24625091
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SMAD2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18729074 9111321
SMAD3 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24424784 19597490 21798735
SMAD3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12202226 12524424
CDK8 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15546612
NOTCH1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14597575 23331499 14500836
NOTCH1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18722525 23331499 16256737
AR CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18794357 20610535
MED12 CDK8 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 30099503
MED21 CDK8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 29568061 9710619 10024883 9315662 26496610 33961781 24981860 23602568 10198638 11867769 10882111
MED8 CDK8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12584197 26496610 33961781 24981860 26186194 23602568 32707033 29568061 26344197
MED26 CDK8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 20098423 24981860 21729782 23746844
MED9 CDK8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 26496610 20098423 33961781 24981860 26186194 23602568 32707033 29568061
MED28 CDK8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 26496610 33961781 24981860 26186194 23602568 29568061
MED29 CDK8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 26496610 33961781 24981860 26186194 23602568 32707033 29568061
MED25 CDK8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 14638676 26496610 20098423 25792360 26186194 14983011 14657022 29568061
CDK8 MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 18418385 15989967 29568061 10024883 26496610 20098423 23322298 33961781 24981860 26186194 23602568 10198638 11867769 10882111
CDK8 MED24 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 29568061 10024883 26496610 23322298 20098423 33961781 24981860 26186194 23602568 10198638 26344197 11867769 10882111
CDK8 MED23 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18418385 29568061 26496610 20098423 11416138 23322298 33961781 25281560 26186194 23602568 32707033 11867769 10353252
CDK8 MED31 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10024883 26496610 24981860 23602568 10198638 29568061
CDK8 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 30695077 29568061 19047373 26496610 20098423 23322298 33961781 24981860 26186194 23602568 10198638 11867769 10882111 23746844
CDK8 MED15 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18418385 26496610 20098423 33961781 24981860 26186194 23749998 23602568 32707033 14657022 29568061 20720539
CDK8 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 29568061 26496610 20098423 33961781 24981860 26186194 23749998 23602568 10198638 11867769 10882111
CDK8 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 30695077 20098423 23322298 19047373 27684187 11867769 20720539 10882111 15175163 30099503 26496610 23602568 29568061 23749998 32707033 23746844 33961781 24981860 26186194 10198638
CDK8 MED14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 18418385 10024883 26496610 20098423 11416138 33961781 24981860 26186194 23602568 10198638 29568061 10882111
CDK8 MED16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 29568061 26496610 20098423 33961781 24981860 26186194 23602568 10198638 11867769 10882111
CDK8 MED20 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 29568061 26496610 33961781 24981860 26186194 23602568 32707033 11867769 10882111
MED29 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 26496610 33961781 24981860 22939629 20133760
MED1 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 15989967 26496610 20098423 23322298 23563140 33961781 24981860 27684187 20133760 26344197
MED10 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 17404243 26496610 14576168 33961781 24981860 26344197 20133760 10882111
MED18 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 26496610 33961781 24981860 20133760 26344197
ESR1 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26487511 11867769 31527615
CDK19 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 30099503 26496610 33961781 24981860 26186194 23749998 23602568 32707033 20133760 23746844
MED4 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21293490 26496610 20133760 33961781 24981860 22939629 25281560 26344197
HIF1A ELOB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23401859 31253590 12050673 12004076 19940151 18323857 17353276
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
CEBPB ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 16651265 7651415 19652226 9817600
MED18 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 29568061 33961781 24981860 20133760 26344197
MED28 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 29568061 33961781 24981860 20133760
MED10 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 10882111 14576168 33961781 24981860 29568061 26344197
MED1 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 29568061 20098423 23322298 23563140 33961781 24981860 20133760 26344197
MED19 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 23563140 14576168 33961781 24981860 21729782 26186194 29568061 26344197
MED29 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 33961781 24981860 22939629 29568061
PPM1K BCKDHA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19411760
NCOA1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20608937 15604093 12738788 11003650 11250900 18451880 11867769 15140878 16282588 11165056 11376110 17627277 14715875 10731636 9259327 17363140 11113179 16606617 12630920 9121466 10760302 26487511 23975195 11682626 12714702 9192902 9192892 23874500 11358671 16713569 11014206 10454579 9773983 12554772 9427757 10598586 10409727 9774463 12574227 16957778
NCOA1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19383905 10698518 19109434
NRIP1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26153859 9115274 16439465 26166704 23403292 33731348 21182203 7641693 9192902 8887632
MED24 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9653119 12837248 11867769 31527615
MED1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18391015 15886699 31527615 10760302 12738788 9653119 10770935 12837248 11867769
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
ESR1 MED14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19805454 11867769 10770935 31527615
AR TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9238003
AR SREBF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 16541421
AR GTF2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12648523 9238003
PAF1 CTR9 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19410543 18469135 30228257 20178742 21726809 26496610 16024656 33961781 20305087 24981860 22939629 26902284 26344197
MED28 MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 15989967 33961781 24981860 20133760
MED19 MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 15989967 14576168 33961781 24981860 21729782 26186194 20133760 26344197
MED10 MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 15989967 24882805 14576168 33961781 24981860 10882111
MED29 MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 15989967 33961781 24981860 22939629 20133760 26344197
MED1 MED4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 24882805 20133760 33961781 24981860 22939629 25281560 26344197
MED1 MED6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 33961781 24981860 22939629 20133760 26344197
MED1 MED18 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 33961781 24981860 22939629 20133760 26344197
MED1 MED20 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 20133760 33961781 24981860 25281560 26344197
MED1 ESR2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500849 21182203 11867769 10770935
MED1 MED24 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 20098423 9653119 33961781 24981860 22939629 20133760 26344197
MED1 MED23 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 20133760 20098423 33961781 25281560
MED1 MED15 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18418385 15989967 20098423 33961781 24981860 14657022 20133760 26344197
MED1 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 20098423 33961781 24981860 17967894 20133760 26344197
MED1 MED14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 9989412 18418385 15989967 20098423 33961781 24981860 22939629 20133760 26344197
MED1 MED16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 20098423 33961781 24981860 22939629 17967894 20133760 26344197
ESR2 MED7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
MED10 MED31 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860
MED18 MED10 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
MED10 MED18 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
MED10 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 12584197 15989967 12149480 17404243 24882805 14576168 33961781 24981860 26344197 10882111
MED10 MED22 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 12584197 15989967 24882805 14576168 33961781 24981860 26344197
MED10 MED29 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 24882805 14576168 33961781 24981860 26344197
MED10 MED4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 15989967 24882805 14576168 33961781 24981860 22939629 25281560 26344197
MED10 MED8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 12584197 15989967 12149480 24882805 14576168 33961781 24981860 26344197
MED10 MED27 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860 26344197
MED10 MED20 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 17404243 24882805 14576168 33961781 24981860 26344197 25281560 10882111
MED10 MED15 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 33961781 24981860 26344197
MED10 MED14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860 26344197 10882111
MED10 MED19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 12584197 15989967 24882805 14576168 33961781 24981860 21729782 26186194
MED10 MED25 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781
MED10 MED11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 12584197 15989967 24882805 14576168 33961781 24981860 22939629 26344197
MED10 MED23 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 25281560 26344197
MED10 MED18 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 12584197 15989967 24882805 14576168 33961781 24981860 20133760
MED10 MED16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860 26344197 10882111
MED29 MED6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 24882805 14576168 33961781 24981860 22939629 26344197
MED19 MED6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 24882805 23563140 14576168 33961781 24981860 21729782 26186194 26344197
MED29 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 15989967 14576168 33961781 24981860 26344197
MED18 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 24882805 33961781 24981860 20133760 26344197
MED17 MED19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 12584197 14638676 14576168 33961781 24981860 21729782 26186194 26344197
MED29 MED11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 24882805 14576168 33961781 24981860 22939629 26344197
MED9 CDK19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 33961781 24981860 26186194 23602568 32707033 22939629
MED28 MED21 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 15989967 33961781 24981860 22939629 20133760
MED29 MED21 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 15989967 33961781 24981860 22939629
MED18 MED21 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 33961781 24981860 22939629 20133760
MED30 MED21 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12584197 15989967 33961781 24981860
MED19 MED4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 14576168 33961781 24981860 21729782 26186194 25281560 26344197
MED29 MED4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 33961781 24981860 22939629 25281560 26344197
MED4 MED9 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 24882805 33961781 24981860 27684187 22939629 25281560
MED27 MED19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 12584197 14576168 33961781 24981860 21729782 26186194 26344197
MED29 MED8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 24882805 14576168 33961781 24981860 22939629 26344197
MED29 MED19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 24882805 14576168 33961781 24981860 21729782 26186194 26344197
MED29 MED20 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860 25281560 26344197
MED29 MED18 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 24882805 14576168 33961781 24981860 20133760 26344197
MED19 MED18 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 24882805 14576168 33961781 24981860 21729782 26186194 26344197
MED19 MED20 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14576168 33961781 24981860 21729782 26186194 25281560 26344197
MED19 MED8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 12584197 14638676 24882805 14576168 33961781 24981860 21729782 26186194 26344197
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
RNF20 RNF40 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MED11 MED6 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MED19 MED8 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TAF6L TAF9B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CTDP1 GTF2B â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CDK19 MED23 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
KAT2B TAF6L â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
SMARCC1 SMARCC2 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
CDK8 MED8 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
GET4 UBL4A â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
ERCC3 GTF2F1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
KAT2B TADA2A â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CDK8 MED6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CTR9 POLR2C â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
MED10 MED20 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
MED4 MED6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
MED11 MED29 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
CDK8 MED21 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MED26 MED7 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MED1 MED13 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
CDK8 MED24 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CDC37 CDK9 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
CDK8 MED15 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
MED21 MED26 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
KAT2B TP53 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CCNC MED12 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
MED1 MED19 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
AQR SNW1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MED10 MED17 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MED29 MED8 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CDK19 MED12 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
MED13 MED14 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
MED10 MED11 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
ACTL6A SMARCC1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
CDK19 MED14 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CDK8 MED1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
CDK8 MED23 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
CCNC MED13 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 28514442 33961781 24981860 26186194 19047373 29568061
MED20 MED6 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 33961781 25281560 26344197 24981860
CDK9 POLR2A â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
DRAP1 TBP â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
POLR2C TBP â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CDK8 MED14 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
GTF2F1 TCEA1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
BUD13 XAB2 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
MED10 MED4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ERCC3 POLR2C â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
KAT2B TRRAP â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CDK8 KAT2B â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 29568061 9710619
SMARCC1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
MED6 POLR2A â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
MED20 MED18 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 25281560
MED20 MED18 â—¼   PROXIMITY ✅ 0.93 0.93 mint 25281560
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
MED14 POLR2C â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
GTF2E1 TCEA1 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
MED13 MED7 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
GTF2H1 POLR2A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MED14 POLR2A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GTF2H1 TCEA1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
MED21 POLR2A â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ERCC3 TBP â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
MED13L MED7 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CCNC MED13L â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
GTF2E1 POLR2C â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
MED11 MED17 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
CCNH POLR2A â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
KAT2B TRRAP â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 9885574 11509179 24981860 12660246 10966108
TCEA1 CDK8 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 10454562 9305922
MED12 MED13L â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
MED10 CCNC â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 15175163 17404243 33961781 24981860 26186194 10882111
MED6 MED7 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 24981860 26186194 22939629
MED6 MED17 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 26344197 33961781 24882805 24981860
MED17 MED21 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22939629 33961781 24981860
MED17 MED22 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
ERCC3 GTF2B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
MED7 POLR2C â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
BUD13 SNW1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
GTF2B GTF2E1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
SMARCB1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
NOTCH1 MAML1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 23022380
GTF2F1 TBP â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
MED21 MED6 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 9734358 33961781 24981860 22939629
MED4 MED17 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 33961781 25281560 26344197 24981860
MED20 MED17 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 33961781 25281560 26344197 24981860
MED17 MED22 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 12584197 24882805 33961781 24981860 26344197
MED11 MED4 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED28 MED30 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 15175163 32296183 11591653 24882805 33961781 24981860 20133760
TADA2A WDR5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
MED14 MED31 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
CDK8 MED13L â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
CDK19 MED13 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
GTF2B POLR2C â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
MED7 POLR2A â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
MED31 MED6 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
POLA1 WDHD1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CDK19 MED13L â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
TADA3 TAF9B â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
GTF2E1 GTF2H3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CDK19 MED7 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CBX3 EHMT2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
POLR2A SMARCA2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
GTF2E1 TBP â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CDK8 MED7 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
CDK8 MED7 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 29568061 10882111 33961781 24981860 26186194 23602568 11867769 10353252
CCNC MED13 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
CTR9 POLR2A â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
MED10 MED21 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 15175163 24882805 14576168 33961781 24981860 10882111
MED28 MED6 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15175163 24882805 33961781 24981860 22939629 20133760
MED11 MED22 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 33961781 12584197 24981860
KAT2B TADA3 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CDK8 POLR2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
SMARCC1 SMARCD1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
POLR2A SMARCA4 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PAF1 WDR61 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
ACTL6A SMARCA2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ERCC3 POLR2A â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
NIPBL SMC1A â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
SMARCA2 SMARCD1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
TADA3 TAF6L â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
POLR2C TCEA1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ACTL6A SMARCB1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
SEC13 SEC16A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
ACTL6A TRRAP â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
CDK7 CCNH â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 9334327 15698475 11113184 15328539 33707221 17643375 8078587 26340423 33476598 8521818 8521393 23602568 29568061 33453189 32707033 22939629 11713533 10958691 8692841 16782892 9218599 33961781 10082552 26186194 9056480 26344197
CDK9 CCNT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 9499409 11145967 15328539 17643375 20562857 9491887 20305087 15713662 19387490 11713532 27684187 14627702 23455922 16980611 26659056 15107825 12588988 12944466 14580347 20153263 22959624 16109377 12115727 21729782 23602568 11282025 30649429 19914168 18483487 24367103 20535204 12832472 19818711 12894230 9872325 23064645 30652970 15713661 21697490 22483617 22939629 32707033 11713533 15528190 15546612 10958691 10617616 10574912 18566585 10465067 24981860 33961781 11689688 17700062 26186194 26344197
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
SMC3 SMC1A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17112726 21111234 31807710 17349791 26496610 10931856 17113138 18832153 11590136 12759374 30021884 22885700 22939629 9789013 31010829 21880767 11877376 23242214 24981860 27173435 11076961 26344197
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
MED10 CDK8 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 15175163 15989967 29568061 10024883 26496610 33961781 24981860 26186194 23602568 10198638 11867769
MED6 CDK8 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32707033 29568061 10198638 10024883 15808511 26496610 11416138 33961781 24981860 26186194 23602568 14983011 26344197 11867769 10882111
MED19 MED31 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 15175163 12584197 24882805 14576168 33961781 24981860 21729782 26186194
MED10 MED6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15175163 12584197 15989967 24882805 10993082 14576168 33961781 24981860 22939629 26344197
MED28 MED17 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15175163 15989967 24882805 33961781 24981860 22939629 20133760
MED18 MED20 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 25416956 12584197 15989967 20133760 33961781 24981860 25281560 26344197
ACTL6A SMARCD1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
CTR9 SUPT16H â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
SMARCA2 SMARCC2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PAF1 SUPT16H â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
TBP TCEA1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
TADA3 TRRAP â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CREBBP STAT1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SMARCC1 SMARCE1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CREBBP NCOA1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MED21 MED31 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CCNC CDK19 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ACTL6A SMARCE1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
SMARCA2 SMARCC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GTF2B TCEA1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
GTF2E1 POLR2A â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
SMARCA2 SMARCE1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
AQR XAB2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GTF2E1 GTF2F1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ESR2 NCOA1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MAML1 RBPJ â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CDK9 CCNT1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 6613869 18483487
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
PAF1 POLR2A â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
SMARCA2 SMARCB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TADA2A TADA3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ACTL6A SMARCC2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
SMAD1 SMURF1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
POLR2A TBP â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CDK7 GTF2E1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
SMARCB1 SMARCE1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
PRMT5 WDR77 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CCNH GTF2E1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
SMARCD1 SMARCE1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
GTF2F1 POLR2C â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
MED10 MED7 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 15175163 15989967 24882805 14576168 33961781 24981860 26186194 10882111
MED14 MED6 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CDK7 GTF2H3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
NIPBL SMC3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
SMARCC2 SMARCD1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CTDP1 POLR2A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED10 MED31 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED10 MED21 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED21 MED7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED6 MED7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED14 MED7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED14 MED21 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED21 MED6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ERCC3 GTF2E1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MAML1 NOTCH1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTDP1 GTF2F1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GTF2F1 POLR2A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MED31 MED7 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MED10 MED14 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
BRCA1 POLR2A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDK7 POLR2A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NOTCH1 RBPJ â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
GTF2B GTF2F1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MED10 MED7 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MED10 MED6 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTL6A SMARCA4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCB1 SMARCD1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CREBBP HIF1A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
POLR2A TCEA1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCA4 SMARCC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMARCC2 SMARCE1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SNW1 XAB2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TOPBP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GTF2B TBP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GTF2B POLR2A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
POLR2A SUPT6H â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCNH GTF2H3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GTF2E1 GTF2H1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCA4 SMARCB1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCA4 SMARCE1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCB1 SMARCC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SMARCB1 SMARCC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCNC CDK8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CTR9 PAF1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCNH ERCC3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ERCC3 GTF2H3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GTF2H1 GTF2H3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BRCA1 E2F1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 AURKA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 SMC3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11877377 15459660 16697054 17102137 17116885 17296725 17582221 18451105 19158510 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 AURKA â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
BRCA1 SMC3 â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 11877377 15459660 16697054 17102137 17116885 17296725 17582221 18451105 19158510 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 E2F1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
BRCA1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 BUB1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
BRCA1 AURKA â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
E2F1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10660629 23285190 18660752 19466541 17106239 20068145 23108140
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
E2F1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9244350 18660752 18319725 11278247 12697828 16713569 12909625
AURKA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22864622 22340593 18026198 24775809 14990569
BRCA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11085509 16713569 11016951
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
CBX5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16687578 16622419 20871592 20011120 25281560 26527279 19111658 16415788 19498464
CCND1 CCNH â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CCND1 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
HIF1A CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23455892 20360945 20179204 15991006
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
ESR2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15313930 14764652 18607069 23891847 11986316 18223478 14729654
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
TP53 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 24189068 8702807 10669755 22270849 12808109 17942917 19086036 20731879 16061648 20554748 24460719 11798189 10082575 15205322 18769160 19800042
E2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10504464 7929342 22768064 19876926 20220142 9584162 17998543 20655656 8618861 8137237 23078099 23543735 10594784
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CCNH CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7533895 19847258 12814430 17386261 16782892 17884153 19667075 15703371 12648680 11900249 12459251 16697054 19809470
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
CDK7 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7533895 19847258 12814430 17386261 16782892 17884153 19667075 15703371 12648680 11900249 12459251 16697054 19809470
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CCND1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCNH GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNH CDK7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK8 CCNH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 28238659 10993082
CCNH CDK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23602568 11113184 8521818 16782892 15698475 15328539 19153657 10082552 26340423 8692841 26186194 9334327 10958691 10734072 9056480 9218599 8078587 8521393 17643375
RPA2 CDK7 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 XAB2 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK7 GTF2H1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RPA2 CDK7 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 XAB2 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 10734072 24424504 25943391 21820033 21157430 28638477
CDK7 CDK11B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16327805
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
CDK7 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23397142 10428966 17050006
CDK7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17591690 11709713 12064478 1088347 16083285 9372954 11483158 9620776 10348343 10884347 16552184 9315650 11007451 9571186 10747897 17898864 1454855 11585729
CDK7 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18079403 27197304 26799765 10886368 14662762 16327805 24662513 26748711 25561469 21331744 19667075 18079404 22137580 9130709 20457598 19901026 19450536 20932174
CCNT1 CDK9 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK9 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
CDK9 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
CDK9 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 22053051 20222012 25023704 14662762 10364292 20106982 18066052 30135578 24385927 18644870 18329373 14517250 20932174 12052871 20226668 19575011 8416977 11575923 16735508
CDK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24173284 9372954 11483158 9315650 19413330 19664995 23603988 24202322 11709713 16083285 1088347 16552184 10884347 24286312 10747897 17942552 16741955 17287340 92065884 12064478 10348343 14702041
TP53 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21715977 20805247 8557038 11795482 17210690 22952705
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
E2F1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21966451 17178887 22508987 21099110 21099103
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
E2F1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22241525 8557038 15706352 21441950 12675512 23954287 12625370
PARP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14627987 20133863
TOPBP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 20413589 18660752 14576433 17006541 12697828 14576432
CDK8 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 20616879 18794899 22945643
GTF2H1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15123636 10428966 16213134
CREBBP E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10753885 15126619 12748276 15123636 8932363
E2F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22480684 11739724 12625370
STAT1 EP300 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10918613 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15265520 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
STAT1 EP300 â—¼   PROTEIN_INTERACTION 22.0 1.0 ACSN 10918613 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15265520 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
MAML1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19304754 16530044 12391150 12050117
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
ERCC3 GTF2F1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2E1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2B â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
TBP ERCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7521915 11089979 22848139 9400991 8087622
GTF2H1 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10403766 10734072 9173976 8194528 15220921 9118947 9130708 8652557 11259578 26340423 17643375
HERC2 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
AR KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18945670 20610535 11328859 23095762
TP53 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9266967 20094059 15153330 17611664 18945670 14614455 17293853
KAT2B NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10747963 22120716 14500836 16713569 23029358
KAT2B SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 34576109 17074756 11058129
KAT2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 19680552 11804596 12068014 16537920 9891054 10490106 14614455 20589832 19788416 12660246 12501250 16959611 19407812 9744860 15965232 16678111 17977830 17189186
KAT2B CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9687573 8684459 9687513 9445475 11864601 9267036 17496784
KAT2B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504
KAT2B SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11058129 15994459
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
TBP MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20886042 7880838 9797456 15876353 14506152
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
MYC CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9632747 19176757 23364919 10523846
MYC ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20920219 21627565 7906953 23421821 20716114
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC TRRAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17848523 23775087 11511535 20194507
MYC AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20890087 20519624 14744757 20682043
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
TRRAP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 17353931 11511539 12660246 20194507 9708738
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
PARP1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9563011 9518481
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
PARP1 SUPT16H â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18406329 16682447
PRKDC RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 26811421 9139719 9295339 21300785 28046023 27999209 23684611 19704001 24332808 18289945 15703371 21558276 21731742 20016603 19473888 24819595 21175350 8760901 33826602 19843584 32989256 24830725 19808869 20154705 17570479 25733714 33636182 18669648 23677613 21376743 14872059 22057367 24639502 17035231 31527085 30030458 20691907 17928296 21107010 22977173 11731442 15060176 23319600 19772495 19847258 26166705 29875999 28506294 10064605 34385259 16731533 33357448 19346677 16697054 8943020
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
TP53BP1 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
TP53BP1 RIF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15342490 23333305 29203878
RPA2 XAB2 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 TOPBP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 XAB2 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 TOPBP1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 TOPBP1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
AR SMARCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535 17721441
SMARCB1 SMARCA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 18414052 23540691 20506188 8895581 31759698
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
SMARCA4 SMARCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 12917342 23540691 9891079 28420882
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
BUB1 SMC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 11535616 17303408 8824189 15279786 12640463 7575488 10477750 17376779 19182530 15024386 9790499 18590585 15604152 17498870 17660363 15592459 19154723 11402067 19503101 18022367
BUB1 SMC3 â—¼   UP_REGULATES ✅ 21.0 1.0 ACSN 10477750 11402067 11535616 12640463 15024386 15279786 15592459 17303408 17376779 17498870 17660363 18022367 18590585 19154723 19182530 19503101 21270334 23197039 7575488 8824189 9790499
NOTCH1 SNW1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 23331499 10713164 11404076 15546612
SNW1 RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 23331499 10713164 10644367
TADA3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12034840 20413580 18089809 16713569
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
TP53 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11514734 18555006 10953306 14741382 19107228 20124454 8274455 16061648 10448271
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
MED1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15848166 9444950 16713569 11118038
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
RNF40 RNF20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21362549 16307923 19410543
RNF20 RNF40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21362549 16307923 19410543
STAT1 TRIM25 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17069755
STAT1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15695802 10848577 9773981 8848048 9037008 16481475 15894584 8986769
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD2 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD2 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   PROTEIN_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD2 â—¼   PROTEIN_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD2 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16052471 11376804 11456453 9812998
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
SMAD5 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20957627 23331499 14534577 16516194 16189514 10531362 15231748
SMAD2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 15613484 17145710 25609649 15817471 20211142 21532621 24584437 18729074 23788427 12419246 16916642 9288972 9892009 21454478 17510063 10531362 15231748 11027280 12167862 21988832 9389648 23331499 12543979 18568018 21071413 19135894 18511908 15467747 12808092 11927552 25514493 15350224 18988627 12732634 10878024 9111321 9311995 9346908 10199400 11264182 12957874 11114293 15761153 11274206 12621041 17272273 24157709 26555259 12374795 22442258 10781087 15922743 11102446 17591701 18783722 16751102 19139564 19917253 9346966 21297662 17283070 12794086
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD3 SMAD2 â—¼   PROTEIN_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
CREBBP SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16751102 18003620 9679056 15750622 17283070 20403362 17074756 15231748
SMURF1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10458166 23331499 15221015 20207742 15231748
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
CREBBP SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15849193 10497242 15467747 18003620 9679056 15990875 15750622 19589780 17074756 17283070 9679060
SMURF1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10458166 23331499 15221015 15761153 15231748
CDK8 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
SMAD3 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 16713569 14638857 18988627
SMAD3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 11248024 11280774 12226080 16713569 11707452
RBPJ NOTCH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22143792 11404076 12700242 24113181
NOTCH1 HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10520600 11120788 10066785 16869730 12814948 7566092 21956839 9819428 10933396 11866432 20007915 10205173 11741889 19165418 15546612
MAML3 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23022380 23331499 12370315
MAML2 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12370315
MAML1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23022380 16530044 11101851 19907488 22100894 21820430 12644465 16713569 12370315 11997524 18427106 11390662
NOTCH1 HES1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23343194 19000719 18495817 16039586 19619488 17143292
NOTCH1 RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 51.0 1.0 Omnipath 23022380 16530044 22143792 25609649 26033182 16530045 21475249 8749394 23103515 16713569 22325781 19907488 23331499 21071413 26496610 18988627 22100894 10637481 26186194 21820430 12644465 10713164 17636029 9032325 12370315 11997524 11390662 19165418 19800882 20028974 30967258 9111040 17284587 17526737
SMURF1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 14701756 17676934 15221015 19914168 21708152 22298955 24828823 19917253 16611643 17510966 15761153 22670624 22152476 17289590 15231748 21685363 27447855
SMURF1 SMAD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17676934 20484049 11278251 15221015 19914168 22298955 18641638 22670624 15231748 12857866
RBPJ HES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10520600 11120788 21311046 10066785 17611704 12814948 9819428 10933396 11866432 10205173 7566092 22718343
NCOA1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10777539 15671023 12748280 11463834 14966289 19194461 9792627 18193094 11747826 17400812 17244199 9223281 10594042
HIF1A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12542982 20547241 17452336 15907483 19489936 15342390 15184875
CEBPB CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17067998 8654374 10818089 15722556 15388792 17599912 12857754
AR CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9822653 15350180 16492776 16344550 11161315 18819102 18031230 20610535
CREBBP SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9651391 16799563 10235267 9765204 8918891
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
CREBBP AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20541699 9822653 15691881 12810069 9482849 16713569
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
CDK8 MED12 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
CDK8 MED13 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
CDK8 CCNC â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 28514442 25416956 30695077 15328539 14681455 20098423 19047373 11867769 10882111 21806996 26496610 23602568 19914168 29568061 26502155 25344755 9710619 10024883 32707033 10353252 23746844 9150135 29997244 11416138 33961781 24981860 26186194 7568034
CDK8 MED12 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
CDK8 MED13 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
CDK8 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
CDK8 CCNC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21806996 23746844 26186194 19914168 20098423 19047373 23602568 7568034 25416956 29997244 10882111 15328539 25344755 9150135 11416138 10353252 26502155
MED12 MED13 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
MED12 MED13 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
HIF1A AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18562694 19828020
AURKA H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14583461 15108802 17938195 15249581 12234980 12588998 12082625
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11500490 18444174 16107878 10318842
BMPR1A SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11438941 24412244 19620713 9136927 16189514 11792802
NCOA1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15514032 12163482 23145053 11673464
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20200160 10379892 16391242 22071320 18414489
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
NRIP1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9192902 23331499 8887632 9115274 7641693 26166704 12554755 26153859 21182203 16439465
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
AR THRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR MED1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17483314 21593191 24778216 23887938
NRIP1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9368054 16527872
TBP GTF2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7666533 8670811 11971135 8946917 9121468 9407004 7706261 16330756 7823952 7609077 8051080 8087622
MAML1 RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23022380 16530044 25609649 26186194 11101851 17145710 16921404 12644465 21475249 26496610 11997524
PRMT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22231400 20084102 15670829
GTF2F1 CTDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12732728 12591939 9765293
POLR2A POLR2C â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
EHMT2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19690169 17194708 22387026
ELOA ELOB â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 7660130 11859374 7660122 7660129 15489290
SREBF1 SREBF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14702347 16282353 9786926 11278785