Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATXN1 ATP5F1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATP5F1B RAD18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATP5F1B PSME3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PCNA CHAF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
CAV1 CAVIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001640 24013648
CAVIN1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001640 24013648
CAVIN1 SEMA6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SF3B6 SRRM2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
H3C2 PARP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
SETD1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18765639
PARP1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
CALCOCO2 ABLIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ABLIM1 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ACACA ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TP53 ATF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
DZIP3 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RAD18 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DAZAP2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
UBE2I ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 TRIM23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 MSMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
BATF3 JUNB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
FANCD2 BRCA1 â—¼   COLOCALIZATION 2.0 0.8 intact 11239454 5213674
CALCOCO2 DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CAV1 MMP14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15466865
DLG5 CD81 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDC5L NKAP â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CHAF1A CDC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
CDC7 RPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CHAF1A DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
UBB DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
DAZAP2 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RPA1 DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
TARDBP DBF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DDX17 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2I DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18762900 11735126
TP53 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20428827
ETF1 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 RPL9 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
FANCD2 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
FANCI UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 HK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27692180
UBE2N HLTF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18719106 0805685105
HLTF UBE2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18316726 0800563105
UBE2A HSPA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA2 SLC7A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MMP14 SDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12904296 12464176
TP53 MSH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12209975
NBN UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RAD50 NBN â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
NKAP SNW1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PDLIM7 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 PDLIM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22266808 15829976
TP53 POLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678112
RAD18 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAD18 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBE2I RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RCHY1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 5220017 17568776
REV1 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RNF10 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF8 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RPA1 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24782567 20705237
RPA1 UBE2T â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20670894 23723247
RPS27A USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
USP7 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 26235645
SHPRH UBE2V2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17108083
TP53 SLC38A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TRIM8 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TARDBP TRIM23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
UBE2I TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
TP53BP1 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53BP1 UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBA52 USP2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBA52 USP7 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
USP7 UBA52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 26235645
UBB USP5 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 7851534
USP5 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26235645 16007098
UBE2N UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RAD18 HEXB â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
RAD18 ARMCX3 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
RAD18 IMPDH1 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
TRIM23 UBA52 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RAD18 SEMA6A â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
CDC5L MSH2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
RAD50 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 10426999
RAD18 SLC5A6 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
RAD18 CENPE â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
H31 FACD2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22828868 29760279
ETF1 RPS27A â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
TP53 UBE2A â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
RAD18 CAV1 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
RAD18 MPI â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
RPS27A TRIM23 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
TRIM23 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
UBA52 USP5 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
RAD18 TMEM33 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
RPS27A SEC61A1 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
RAD18 ARHGEF39 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
PCNA UBA52 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
RAD18 EIF3M â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
SF3B6 SNW1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
RAD18 TP53BP1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
RAD18 MRPL21 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
RAD18 ZC3H8 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
RAD18 PGM1 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
UHRF1 CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28803780 34079125
CDC5L FACD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31180492 20467437
H31 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 24981860
H31 RAD50 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 26527279
ZN263 ZMYM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN263 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLDC3 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RS2 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
SRP09 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PI42A SRRM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PI42A RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
L2GL2 UBE2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN692 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARRB2 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ATF2 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BATF3 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ORC2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25184681 17525332
BRCA1 CENPF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
RAD18 CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31076518 34079125
SRRM2 CDC5L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
CDC5L RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31076518 20467437
DHX57 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FADS3 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SHPRH HLTF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21396873 18719106
IRF9 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
JPH4 UBE2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
JPH4 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
JUNB RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAD18 ORC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22681887 32296183
RAD18 PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31076518 34079125
RAD18 PTRF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 27377895
TXNIP RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SNW1 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31076518 20467437
EIF3M RPS2 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
EIF3M RPS27A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
RAD18 PPFIBP1 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
RAD18 SRSF10 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
RPS2 SRP9 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
RPS27A SRP9 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
SRP9 UBA52 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
RAD18 NAAA â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
RAD18 LSM6 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
RAD18 HSPA2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
RAD18 MMP14 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
RAD18 ABLIM1 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
RAD18 PDLIM7 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
RAD18 RANBP1 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
FBXO18 PCNA â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
H1FX HIST1H2AB â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
SEC61A1 UBA52 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
REV1 RPS27A â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
RAD18 ACACA â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
PCNA UHRF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26496610 30357346
RS2 DHX57 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZN501 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
L2GL2 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24366813
RAD18 F178A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26496610 24981860
BRCA1 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25184681 29656893 23901102
PSME3 PCGF6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PSME3 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZFP41 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TULP3 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33187986
UBE2A UBE2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 25582440
RAD18 LINGO1 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
TRIM27 USP7 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX3 PCGF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
RAD18 ALDH6A1 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
RAD18 UBE2T â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
RAD18 FANCD2 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
PCNA POLN â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
LSM6 SF3B6 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ATF2 BATF3 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRCA1 FANCD2 â—¼   UBIQUITINATION ✅ + 0.83 0.83 Signor 12485996
FANCD2 RPS27A â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
RAD18 RPS27A â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
RAD18 RIPOR2 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
BRCA1 UBE2N â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
RAD52 TP53BP1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
RAD18 IFI30 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
PARP1 UBE2I â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
RAD18 LCP1 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
H31 PCNA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33029857 26527279
RAD9A PCNA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12400013 16189514 11994305
FACD2 RAD18 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20967207 25893307 21355096
TP53B RAD50 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20010693 29656893
PARP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 34079125 26831064 25252691
SNW1 MSH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12840015 20467437
RAD18 MARCHF6 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
SHPRH HSPA2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
ETF1 RPS2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
FANCI UBB â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
RPL9 SRP9 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
RAD18 BAG1 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
RAD18 SRPRB â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
RAD18 INTS11 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
UBB USP5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
RAD18 FADS3 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
CBX3 CHAF1A â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ORC2 RAD18 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
RPS2 SEC61A1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
RAD18 S100A10 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
ARRDC3 UBA52 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
REV1 UBB â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RPS27A TP53BP1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PCNA FACD2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19704162 25893307 31180492
PARP1 UHRF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31964471 24782312 34079125
RAD18 ANR32 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 26496610 24981860 22036607
RNF8 NBN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26869104 18001825 23115235
RAD18 GLRX5 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
RAD18 TYRO3 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
RAD18 FAM162A â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
RAD18 TRIM27 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
RAD18 MSMO1 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
RAD18 HEATR3 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
RAD18 SATB2 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
MSH2 LCP1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
RAD18 SLC7A8 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
RAD18 ASF1A â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
RAD18 SEC61A1 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
RAD18 PAK1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
FANCD2 UBB â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
HLTF S100A10 â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
RAD18 NKAP â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
RAD18 PCNA â—¼   UBIQUITINATION ✅ + 0.86 0.86 Signor 19706603
TP53B NBN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20010693 29656893 20081839
SMC6 TP53B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 29656893
H31 SHPRH â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 34079125 31434570 25281560 28400511
UBB RAD18 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28506460 24981860
ATF2 JUNB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
H2AFZ HIST1H2AB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CDC5L SF3B6 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
BRCA1 MSH2 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
MRE11A RPA1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
RAD18 LIPA â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
RAD18 SEC24D â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
MSH2 SNW1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
RPS27A USP2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
RAD18 AMIGO3 â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
RPL9 SEC61A1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
RAD18 DDX17 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
PGK1 PCNA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26030842 20849852
FACD2 RAD50 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19609304 31180492
FACD2 RAD51 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27694619 12239151 25893307 30818369
F178A ANR32 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32389690 26496610 33961781
BRCA1 MRE11A â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SART3 LSM6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 28514442 27173435 33961781
UBA52 USP7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RAD18 GM2A â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
UBA52 UBE2V2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PCNA UBE2I â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RAD18 KCTD10 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
FANCM PGM1 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
CHAF1A PCNA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RAD18 DHX57 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
RAD18 SUMF2 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
RAD18 SLC38A2 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
PCNA TP53BP1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
FANCM RAD52 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
RAD18 CD81 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
BRCA1 RPA1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
RAD18 RNF145 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
RAD18 UHRF1 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
H31 PARP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 32937373 28190768 20080577 29568061 20504901 34079125
SMC6 F178A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32389690 26496610 33961781
ASF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
H3C2 ASF1A â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 7219095 19498464
H3C2 ASF1A â—¼   PROXIMITY ✅ 0.88 0.88 mint 25281560
BRCA1 CBX3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23074186 25184681 25634209 34079125
RAD51 RAD18 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19396164 25893307
RAD18 RAD51 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DBF4 ORC2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MAPK8 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CAV1 PTRF â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
HLTF RAD18 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
RAD18 SDF4 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
PCNA UBB â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
RPL9 RPS2 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
RCHY1 TP53 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
UBB USP2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RAD18 UXS1 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
RAD18 PCNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21967848 28924044 21227930 20675655 32701997 21858012 20064529 28831681 33508099 17108083 18363965 23345618 26170230 17720710 24958773 15359278 31873223 18245774 30700555 31887036 30563767 20600238 22904075 31160570 27377895
MCL1 PCNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10978339 26030842
FACD2 NBN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19609304 12447395 31180492
RAD18 TP53B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19228710 29656893
H31 TP53B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16415788 17190600
TP53B BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22884692 17525332 21552324 29656893 12364621 31009828 18001824 26831064
MAGA4 RAD18 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 26186194 28514442 27377895
JUNB ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 16511568 20102225
BATF3 ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 23661758 20102225
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10426999 29656893 10783165 11504724 25659039 25939603 25184681 19244116 18171670 12124328
SNW1 CDC5L â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 29395067 12840015 20467437
TP53 RCHY1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 17568776 5220017
TP53 RCHY1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 17568776 5220017
UBE2N RNF8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22589545 31048496 20023648 16215985 22814251 23255131 28244869 25909880 19549727 21706008 26285145 18678647 24732096 31792955 27909234 21911360 29523790
HLTF UBE2V2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
NKAP SRRM2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RAD18 DLG5 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
SHPRH SDC1 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
MAGEA4 RAD18 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
RAD9A RHNO1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RAD18 AP1G2 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
RAD18 SNRNP27 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
RAD51 TP53 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FANCI RPS27A â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
TSG101 UBA52 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
RAD18 DTL â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
PCNA HLTF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
PCNA DTL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16861906 25154416 21725088 30301766 30623174 29424068 20129063
E2F3 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15510213 18319725 11491305
HLTF PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18719106 26350214
H3C2 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
FANCI FACD2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21719678 25168188 18931676 19561358 32510829 24794430 25319828 28684355 25489943 24451376 30456385 24623813 23993743 27773793 31180492 17460694 28575658 25862789 33795880 20603015 22855611
FACD2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14499622 25652403 31180492 29656893 11239454 16713569 12887909
ASF1A H31 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20393127 33961781 24981860 26167883 10759893 22407294 34079125 29568061 18971269 23828041 19498464 14718166 28514442 20504901 25281560 15664198 19410544
PAK1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12151336
RAD51 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11498787 31270457 19369211 14636569 24085845 29656893 28319063 25659039 34408138 31009828 9774970 16713569 25499220 19766185 17302439 9008167 28976962
JUNB BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 18259752 16713569 28514442 25184681 12080089
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
E2F3 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17106239
BRCA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17873885 11320250 14636569
BRCA1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 9774970 9008167
UBA52 DAZAP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBE2I DDX17 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22713328 19995069 25114211
UBE2B HLTF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
TP53 MSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11350971 8630028
SHPRH RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
UBE2N RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2V2 RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
RPA1 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
UBE2I SATB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23750026 25391492 14701874
UBE2N SHPRH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
UBE2B SHPRH â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
TP53 TMEM33 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 UBA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
UBE2N UBE2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2B UBE2V2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
RAD18 SF3B6 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
RNF8 UBE2N â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RAD18 NACC1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
RAD18 SDC1 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
RAD18 DDX28 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
UBB UBE2V2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
RAD18 CALCOCO2 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
RPS27A UBE2V2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
RAD18 LGMN â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
MSH2 PCNA â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
RAD18 SAT2 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
CHAF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PROXIMITY ✅ 0.91 0.91 mint 25281560
TP53 ARHGEF39 â—¼   KO_DOWN_REGULATES ✅ - -0.92 0.91 PKG 28854368
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
RAD18 UQCRQ â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
RAD18 MCUB â—¼   KO_DOWN_REGULATES ✅ - -0.92 0.91 PKG 28854368
ATF2 MAPK8 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
RAD18 PGK1 â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
RPA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RAD18 NPC2 â—¼   KO_UP_REGULATES ✅ + 0.92 0.92 PKG 28854368
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
RAD18 SV2A â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
RAD18 PRELID1 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
RAD18 RPL9 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
RAD18 DNMT3B â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
FBXO18 RAD51 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
RAD51 UBE2I â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
REV1 POLK â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 26982350 19170759 15189446 15380106 26903512
RAD18 ARL1 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
RAD18 ETF1 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
RAD18 UBB â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RAD18 ITGB5 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
RAD18 SLC7A1 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
NBN RAD50 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
MRE11A TP53BP1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
TSG101 UBB â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
PCNA RPS27A â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
TP53 RPL22L1 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
PCNA MSH2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 8858149 16189514 12171929 15225546
UBB USP7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
SNW1 SRRM2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RAD18 ACSL4 â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
RAD18 ZNF771 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
RPS27A USP5 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
RPS27A USP7 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
HLTF UBE2N â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RAD51 RPA1 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
RAD18 UBA3 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
RAD18 PDLIM1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
UBB UBE2N â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
RAD18 XPO6 â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
RAD18 AASS â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBE2N â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
MRE11A NBN â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
RAD18 ZWILCH â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
RFC2 PCNA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 8093561 9228079 26496610 24958773 12171929
UHRF1 H31 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 32428527 25281560 33097091 22064703 32144273 34079125 30392931 29506131 30639225 32609811 31018966 14993289 17967883 22096602
H31 CBX3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 24981860 20011120 33097091 16415788 34133717 24576085 15136563 26527279
CDC5L SRRM2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
RAD18 MT1E â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
RPS27A UBE2N â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
RAD18 SRPRA â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
RAD18 ARRB2 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
RAD18 GRID2 â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
RAD18 LPCAT3 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
RAD18 MCL1 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
RAD50 NBN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 19197236 22939629 12679336 10426999 26344197 17526493 9705271 12607003 17612497 12447395 22464731 34348893 11062235 15758953 12124328 11238951 26215093 23530059 15734743 16391231 24651726 30179224 17500065 30440001 22941933 10783165
RAD52 RAD51 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28551686 9826763 20190268 12750383 17118963 9837724 10666456 15766559 19338310 10212258 8550550 10448035
RPS27A TSG101 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
HLTF PCNA â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
DTL PCNA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
UHRF1 USP7 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PCNA SPRTN â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RPA1 TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RAD18 DHCR7 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
RAD18 RNF10 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
ACACA BRCA1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CDC7 DBF4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
FANCM RPA1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RAD18 SLC20A1 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
RAD18 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
RAD18 H1FX â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
PCNA RAD18 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RAD52 RPA1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UBA3 UBE2M â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RAD18 RPL22L1 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
RPS27A TP53 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RAD18 USP1 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
LSM6 SART3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RAD18 UBE2A â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL9 UBA52 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
PCNA RPA1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MRE11A RAD50 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC5L SNW1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RAD18 UBE2B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL9 RPS27A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS2 RPS27A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS2 UBA52 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL9 RPS2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA FANCD2 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA RAD51 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA FANCI â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA REV1 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15189466 15703371 16337601 16337602 16697054 17035102 17517887 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 20227374 22021614 22266823 22562137 23065650 23414611
PCNA POLK â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11900249 12466554 12648680 12930902 14624239 14657033 14726013 15189446 15189466 15459660 15703371 16697054 17035102 17116885 17296725 17582221 17652783 17884153 18087292 18157158 18196958 18584027 18677104 18809224 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22266823 22743550 23065650 23414611 24050180 8264637 8978692
PCNA BRCA1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA POLK â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11900249 12466554 12648680 12930902 14624239 14657033 14726013 15189446 15189466 15459660 15703371 16697054 17035102 17116885 17296725 17582221 17652783 17884153 18087292 18157158 18196958 18584027 18677104 18809224 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22266823 22743550 23065650 23414611 24050180 8264637 8978692
PCNA FANCD2 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA RAD51 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA FANCI â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA BRCA1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
UBE2N PCNA â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10880451 16224103 16518696 17652783 18157158 18196958 18525240 18647995 19217833 19258535 19851286 20675655
USP1 PCNA â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
RAD18 PCNA â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10884424 15280666 15688063 16611994 16824193 17652783 18157158 18196958 18363965 18498753 19013543 19258535 19396164 20129063 20675655
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
UBE2N PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 18772547 12820959 18525240 19459846 19258535 19440234 17652783 15147722 10880451 15169778 19851286 10722742 18647995 18006823 18157158 16224103 20675655 16518696 18196958 15340381 10721693
RAD18 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18363965 19706603 17652783 18196958 18498753 20129063 21227930 10884424 19013543 18157158 15280666 19258535 16611994 19396164 20675655
SHPRH PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 19706603 17652783 18196958 19851286 16789823 18719106 18525240 18647995 18157158 10880451 19258535 16224103 20675655 16518696
UBE2A PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18363965 10884424 12820959 19459846 19258535 19440234 17652783 15147722 15169778 19706603 18498753 12226657 20129063 10722742 18006823 18157158 16611994 20675655 18196958 15340381 19013543 15280666 19396164 10721693
USP1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 19264559 35324534 19686080 18082604 23589330 20353596 19622404 19075014 16531995 18082605 19217432 18931676 33619839
TP53 UHRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 23677994 19501055 18220474 21382456
H3C2 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
ASF1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15664198 10759893 11985607
BRCA1 ACACA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11877377 15459660 16326698 19793801 20029420 21060331 21337561 25979092
BRCA1 ACACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 16698035 19061860 12360400 24565757 18452305 16713569 16326698
MAPK8 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 11279118 17081983 20506250 12958075 9162092 19255142 8654373 20028971 15105425 17626013 12788955 11566021 15550563 10777545 23331499 7535770 15068801 21071413 17875713 9317150 16393692 15304344 18988627 7737130 26538579 21444723 602896 11896587 12110590 7824938 11274345 12874243 11971971 9399639 19436832 16533805 9670022 9029150 11865055 9207092 12804775 7737129 15212693 9405416
DZIP3 ATXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 32814053 16713569 24326307
BRCA1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 FANCD2 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 FANCI â—¼   PHYSICAL_INTERACTION 55.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 FANCD2 â—¼   SHARES_COMPLEX 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 FANCI â—¼   SHARES_COMPLEX 55.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
USP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
RAD50 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10783165 16260778 16391231 10426999 11504724 25084169 25184681 16713569
BRCA1 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12887909 12485996 11239454 25652403 14499622 16713569
TP53 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10684646 20610713 17014845 11076533
DBF4 CDC7 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
CDC7 RPA1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
DBF4 RPA1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 7575488
RPA1 DTL â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
FANCD2 FANCI â—¼   PHYSICAL_INTERACTION 66.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14614141 14624239 14726013 15242590 15375219 15377654 15459660 15485915 15703371 16337601 16337602 16697054 16713580 16818604 17303408 17349954 17965729 18082604 18082605 18085520 18087292 18448394 18472307 18543256 18584027 18809224 18931676 18995830 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20064462 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 POLN â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 16337601 16337602 16697054 17965729 18087292 18448394 18472307 18584027 18809224 18931676 19622404 19686080 19772495 19793861 19793862 19841479 19847258 19995904 20064462 20723763 22101340 22751496 23444773
FANCD2 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
FANCD2 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 RAD50 â—¼   PHYSICAL_INTERACTION 63.0 1.0 ACSN 10882712 11850621 11877377 12086603 12556884 12607003 14988723 15136767 15175241 15211575 15459660 15498778 15798197 15964794 16163361 16332722 16337602 16531125 16581787 16713580 16805667 16858402 17036055 17102137 17116885 17296725 17303408 17384638 17582221 17713585 17965729 18087292 18171670 18469862 18584027 18677104 18809224 18931676 18995830 19151707 19282663 19342888 19362533 19622404 19654615 19686080 19772495 19793801 19793861 19793862 19805513 19841479 19892829 20051983 20064462 20723763 21376743 22743550 22751496 23444773 24050180 24089143 24095737
FANCD2 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 FANCI â—¼   SHARES_COMPLEX 66.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14614141 14624239 14726013 15242590 15375219 15377654 15459660 15485915 15703371 16337601 16337602 16697054 16713580 16818604 17303408 17349954 17965729 18082604 18082605 18085520 18087292 18448394 18472307 18543256 18584027 18809224 18931676 18995830 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20064462 20173781 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCD2 POLN â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 16337601 16337602 16697054 17965729 18087292 18448394 18472307 18584027 18809224 18931676 19622404 19686080 19772495 19793861 19793862 19841479 19847258 19995904 20064462 20723763 22101340 22751496 23444773
FANCD2 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
FANCD2 RAD50 â—¼   SHARES_COMPLEX 63.0 1.0 ACSN 10882712 11850621 11877377 12086603 12556884 12607003 14988723 15136767 15175241 15211575 15459660 15498778 15798197 15964794 16163361 16332722 16337602 16531125 16581787 16713580 16805667 16858402 17036055 17102137 17116885 17296725 17303408 17384638 17582221 17713585 17965729 18087292 18171670 18469862 18584027 18677104 18809224 18931676 18995830 19151707 19282663 19342888 19362533 19622404 19654615 19686080 19772495 19793801 19793861 19793862 19805513 19841479 19892829 20051983 20064462 20723763 21376743 22743550 22751496 23444773 24050180 24089143 24095737
USP1 FANCD2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
UBE2T FANCD2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 12239151 16916645 18931676 19264559 19622404 19686080 20457011 22615860
FANCD2 RAD50 â—¼   ENZYMATIC_REACTION ✅ 63.0 1.0 ACSN 10882712 11850621 11877377 12086603 12556884 12607003 14988723 15136767 15175241 15211575 15459660 15498778 15798197 15964794 16163361 16332722 16337602 16531125 16581787 16713580 16805667 16858402 17036055 17102137 17116885 17296725 17303408 17384638 17582221 17713585 17965729 18087292 18171670 18469862 18584027 18677104 18809224 18931676 18995830 19151707 19282663 19342888 19362533 19622404 19654615 19686080 19772495 19793801 19793861 19793862 19805513 19841479 19892829 20051983 20064462 20723763 21376743 22743550 22751496 23444773 24050180 24089143 24095737
FANCM FANCD2 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
UBE2T FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18931676 22615860 12239151 19622404 17768402 19686080
USP1 FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19264559 19686080 18082604 23589330 36170365 19622404 19075014 16633336 18082605 19217432 18931676 15694335
FANCM FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22615860 19622404 12972610 23253856 15136767 19282663 14988723 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCI FANCD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21719678 22855611 24451376 17460694 27773793 20603015 25168188 19561358 18931676 24623813
FANCI RAD51 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
FANCI POLN â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 16337601 16337602 16697054 17965729 18087292 18448394 18472307 18584027 18809224 18931676 19622404 19686080 19772495 19793861 19793862 19841479 19847258 19995904 20064462 20723763 22101340 22751496 23444773
FANCI POLN â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 16337601 16337602 16697054 17965729 18087292 18448394 18472307 18584027 18809224 18931676 19622404 19686080 19772495 19793861 19793862 19841479 19847258 19995904 20064462 20723763 22101340 22751496 23444773
FANCI RAD51 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
UBE2T FANCI â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 12239151 16916645 18931676 19264559 19622404 19686080 20457011 22615860
FANCM FANCI â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
USP1 FANCI â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
USP1 FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19264559 19686080 18082604 23589330 17488615 19622404 19075014 18082605 18985065 19217432 18931676
UBE2T FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 22615860 19622404 17768402 19686080
FANCM FANCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22615860 19622404 12972610 23253856 19282663 8020957 24095737 18931676 22266823 16697054 24089143 23444773 19772495 19847258 18550849 21948210 22657828 20832754 19686080 12535671
FANCM RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
HEXB GM2A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 2970528 1720305 527942 16698036 2971395
SEC24D GOLGA2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 10903204 11306556 23378591 9150144 10679020 11285137 23698585 11927603 16624868
MAPK8 JUNB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8917518 18669648 9889198 20068231 9405416
TP53 MAPK8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22607268 23376463 18374905 15958553 10854211 22353755
MAPK8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 11108663 12531896 16713569 11283254 10706102 19651615 27147566 9724739 15538975 9732264 10581258 10436023 17570479 9393873 11896587 12514174 15580310 18813780 11078726
MAPK8 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12223490 20696142 17463001 17670986 18676833 26538579
TP53 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11160159 19808698 11832478 18208354
NBN PARP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
PAK1 PGM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15378030
PARP1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
POLK REV1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15189466 15703371 16697054 17035102 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 20227374 22021614 22266823 23065650 23414611
POLK REV1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11756412 12466554 14624239 14657033 14726013 15189446 15189466 15703371 16697054 17035102 17652783 18157158 18196958 18931676 19217833 19225445 19258535 19622404 19686080 1974050 19847258 20227374 22021614 22266823 23065650 23414611
RPA1 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
REV1 RAD18 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10884424 12466554 14657033 15189446 15688063 16337601 16337602 16611994 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 20129063 20675655 22266823 22562137 23065650
REV1 RAD18 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10884424 12466554 14657033 15189446 15688063 16337601 16337602 16611994 16824193 17035102 17652783 18157158 18196958 18363965 18931676 19013543 19217833 19225445 19258535 19396164 19622404 19686080 20129063 20675655 22266823 22562137 23065650
RAD51 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
USP1 RAD51 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
TP53 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513613 16322760 20802511 16398215 18769160
RAD52 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15766559 17145710 9826763 20190268 17118963 10666456 12750383 9837724 19338310 10448035 10212258
TP53 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 8617246 11002423 16713569 16322760 16983346 9380510
RPA1 RAD9A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RCHY1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 21988832 19483087 17568776 24367557 25116336 21084285 12654245 21791603 20452352 19043414 16713569 31630802 27519799 19918835
RNF8 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 18001824 18006705 19203579 19772495
RNF8 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20023648 21911360 22589545 25909880 16215985 24732096 18678647 26285145 23255131 22814251 19549727
RPA1 UBE2B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
TP53 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18172499 18695251 24667498 22056774 17290220 17592138 12421820 18413597 20173098 19556538 21857681 17470788 18359851 19805293 19196987 12640129
UBE2N TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 17349954 17652783 18196958 19203579 19258535 19793861 19793862 19841479 19851286 22771115
UBE2M UBA3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 25531226 15361859 19250909 17220875
RAD18 UBE2N â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
SHPRH PGM1 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
TP53BP1 LCP1 â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
RNF8 SLC7A8 â—¼   KO_DOWN_REGULATES ✅ - -1.29 1.28 PKG 28854368
TP53BP1 CAV1 â—¼   KO_UP_REGULATES ✅ + 1.29 1.29 PKG 28854368
SHPRH CAV1 â—¼   KO_DOWN_REGULATES ✅ - -1.43 1.42 PKG 28854368
TP53BP1 CAVIN1 â—¼   KO_UP_REGULATES ✅ + 1.46 1.46 PKG 28854368
SHPRH MT1E â—¼   KO_DOWN_REGULATES ✅ - -2.59 2.58 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368