Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SATB2 IGHM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14701874
PAX8 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9413150 11453662
FOXI1 PAX8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12702667
AXIN2 PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0604206103 16815967
RUNX2 AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19585539 23300083
HNF4A AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19149881 11940574
BCL11B HDAC1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
RUNX2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17517365 23073173
BCL2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15210690
NR4A2 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11884409 20533997
TLX1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23628015 24548444
SATB2 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
TP63 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21930790 17935121
MEIS2 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21746878
TP63 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22777354 23837456
GATA3 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20189993
PAX6 CDH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19666824
CREB1 HBG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22469229 19861239
HNF1B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671480
CREB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
GATA3 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536859
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
HDAC1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
SMAD5 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
SMAD1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
TP63 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17632082 19719829
GATA3 ZEB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20731704
MYB GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17641686
SOX6 HBE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17309816 16462943
MYB HBG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16631597 21092141
KAT2B IRF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10022868 11304541
NANOG LEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 32448362 25921273
SOX17 LEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17218525 17875931
RUNX2 LEF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20890621 19650108
LEF1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16575901 16043491
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
MEIS2 PAX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12183364
MEIS2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20523026 12183364
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
MYB NFIB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20647765 19841262
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
SATB2 NANOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28167342 19933152
POU5F1 NANOG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17211451
SOX2 NANOG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17211451
NFIA NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
NFIB NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
SATB2 NR4A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31666685
SMAD1 PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19664780 24692107
SMAD1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17215250 22298955
SMAD1 SATB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
SMAD5 SATB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
SOX5 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD5 SOX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNAI1 ZEB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21317430 12161443
MTA2 NANOG â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
LMBL1 SATB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CNDH2 SATB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MO4L2 DISC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31413325 32296183
MO4L2 SATB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CF141 SATB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASB3 SATB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CPNE5 MTA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DPY30 MTA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 23995757
FOXF1 SATB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 33961781
HSFY1 SATB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SMAD1 LEF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10890911 15750622
SOX2 TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
POLB SATB2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
KLH20 SATB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NADC SATB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MAGAA KAT2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MAGAA SATB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RFPLB SATB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ERG RUNX2 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
LHX6 SATB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SOX2 NFIB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 28794006 21532573
PLK1 SATB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
NANOG SOX2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PIAS1 ELK3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 15580297
SOX5 SOX6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 9755172 33961781
RUNX2 SMAD1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RAD18 SATB2 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
FOXL1 SATB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 35140242
SOX2 PIAS1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
SMAD5 RUNX2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10531362 22966907
ASB3 DISC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 31413325
NFIB NFIA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26871637 35140242
HDAC1 SNAI1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MYC PLK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29467282 27773673 30415952 17314511 33494392
GATA3 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34026424 29453984 26028330 31409898
KAT2B IRF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23670564 10022868 11304541
SMAD1 SKI â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14699069 12874272 12426322
POLB QPRT â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
MYC POLB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19149881 24299953
MYC CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22002305 22911891 19738061
LEF1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22933707 17452626 8892228
ZEB1 CDH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23160379 18381457 17615296
MYC DPY30 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
MYC KAT2B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 12660246 15572685
LEF1 NANOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21689639
LEF1 SNAI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20128911 16179074
MYC MEIS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
SMAD1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 15576399 22290435 22761862
NFIC NFIB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 9099724 25258084 28514442 16189514
NFIB NFIX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 9099724 26871637 28514442
NFIB NFIX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9099724
PAX6 PAX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10804178 11003833 12721955
PIAS1 SATB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14701874
SOX2 PROM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22937156 21947321 23326489
SUMO3 SATB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23750026 25391492 14701874
UBE2I SATB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23750026 25391492 14701874
HDAC1 MO4L2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 14506250 17573780 20332121
MTA2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6613464 18451879
POLB MORF4L2 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
HDAC1 MTA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
NANOG POU5F1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
PIAS1 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
SUMO3 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
POU5F1 SOX2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FOXI1 PAX8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15459102 15188428 12538519 15604103
LEF1 TBXT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10704849 12032083 12234972 11447280 14575694 18948405 15292219 15579438 16139800 14557550 10953028
LEF1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19751508 7542250 8666229 11955436 11967263 22270359 16940750 12051714
HDAC1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
SATB2 BCL11B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 31666685 18255031 18255030
MYC BCL2 â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
MYC BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8036017 17404573 12695333 24167291 18809243 19201832 16316993 19649202
MYB BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22101269 23675407 20237898 17823980 20659323 10692454 9096387 11675351 12384144 16088151 9823328
CDH1 CDH2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH1 CDH2 â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
SNAI2 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 23031797 23189137 23054398 11912130 21081648 23160379 20455091 19635798 16943193 24424621 15300012 20139075 24703882 12855644 23637992 23518002 19448627 16273209 18385519 20071775 22933707 24297167 20332115 17655524 22899291 22567133 20053763 15311212 21593765 19389926 20182623 21796367
MYC CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9632747 19176757 23364919 10523846
ZEB1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 17997862 16424029 17615296 23890107 23160379 19435871 18411277 23667256 20139075 12508111 12714599 23518002 20207041 16862183 22249256 18321996 18805502 19706487 19839049 22147512 23743934 15674322 19921427 16804902 20332115 10949939 21771732 18487993 17655524 15311212 12161443 21593765
HDAC1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20580679 19182791 21685935 21184735 24424621 18794357
SNAI1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 71.0 1.0 Omnipath 16502042 16424022 18347060 19874710 23054398 11912130 12668723 21081648 24168186 20455091 16617148 19635798 24424621 15300012 22775504 12508111 25025961 23637992 20576520 24228088 18701475 20562920 22562246 23424071 21685935 15026811 24504364 18801366 19055748 18321996 17060462 23295740 22128911 23752226 24293287 16273209 19893985 18385519 23671646 17724139 24305977 20801642 10655587 15492833 19789323 21846773 19784072 17082242 17671186 22911555 14673164 16804902 17490644 23658826 18519590 12579345 22158034 17655524 24095903 18565826 20053763 15311212 15448698 19179606 12161443 22614005 18773488 21796367 24448241 16322400
ZEB1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 15169839 9389648 17615296 22796940 19839049 20818389 21224848 20519943 21685935 12508111 11309385 11074002 225147423 19597490 12743038 14673164
SNAI1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 15169839 17615296 22796940 20818389 21685935 20519943 12508111 11309385 17018611 22514743 19597490 14673164
SNAI2 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 15169839 17615296 22796940 20818389 21685935 22370643 20519943 12508111 17508028 11309385 19597490 14673164
CREB1 NR4A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22294685 11884470 12114266
GATA1 GATA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19114560 12432220 20670937 14695898 21853041
GATA1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24336126 19522008 12832487
GATA1 HBG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 1379347 1688723 16200778 20395365 2336386 19114560 24245781 21609963 19447160 18443038 2474800 21220744 2734104 8445949 12567445 8262042 12609092
GATA2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19522008 22951020
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
SNAI1 HDAC1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 SNAI2 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
SNAI1 HDAC1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 SNAI2 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 SNAI2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HNF1B HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10518495 8290348 11585914 16479257
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
IRF1 MYC â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10485906 10820262 11399519 11875494 12417340 12433365 15644117 16127449 16597464 17260466 17689680 18345002 21097505 22461508 23390297 6357187 8871614
LEF1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19620402 18202148 17132729 19653274
LEF1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
LEF1 SNAI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20731704 19751508 7542250 11967263 22406545 17093497 21317430 11955436 22270359 18832382 12051714 8666229 12490555 16510505 16940750 21199805 17550342 16831886 14623871
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
UBE2I MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11779867 16713569 22910413
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
POU5F1 NANOG â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20925113 17506876 16153702 20526341 19829295 22855527 17068183
SOX2 NANOG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17068183 16153702 21816365 19829295
SOX2 NANOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22745796 23939864 15860457 18537119 17324942 19522013
POU5F1 NANOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18662995 22745796 15860457 20505756 18537119 19522013 18687992 17272500 18338330 17068183
NFIB NFIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9099724 25258084 16189514
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
SKI PAX9 â—¼   DOWN_REGULATES ✅ - 16.0 1.0 ACSN 11001584 12435627 15087129 16054035 16169709 16396903 16406505 16413481 16880536 17000779 19032343 19114989 19809516 20107231 20562908 9216996
POU5F1 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20505756 12136102 17324942 15988017 17068183
SNAI1 ZEB1 â—¼   UP_REGULATES ✅ + 66.0 1.0 ACSN 10048576 11283614 11708773 12490555 12545156 12668723 14623871 14673164 15111329 15151915 15155580 15181457 15448698 15459715 16001073 16079281 16232121 16510505 16556862 16617148 16716598 16831886 17018611 17055429 17093497 17403902 17490644 17537911 17550342 17563753 17615296 17671186 18172008 18297062 18832382 19208835 19412634 19564415 19597490 19935649 20027199 20702634 20706219 20713526 20731704 21041997 21051859 21159887 21199805 21317430 21577210 21685935 21883379 2191300 22006115 22286765 22406545 22439866 22514743 22796940 22945800 23140366 23869868 8844971 9157999 9618481
SNAI1 SNAI2 â—¼   UP_REGULATES ✅ + 66.0 1.0 ACSN 10048576 11283614 11708773 12490555 12545156 12668723 14623871 14673164 15111329 15151915 15155580 15181457 15448698 15459715 16001073 16079281 16232121 16510505 16556862 16617148 16716598 16831886 17018611 17055429 17093497 17403902 17490644 17537911 17550342 17563753 17615296 17671186 18172008 18297062 18832382 19208835 19412634 19564415 19597490 19935649 20027199 20702634 20706219 20713526 20731704 21041997 21051859 21159887 21199805 21317430 21577210 21685935 21883379 2191300 22006115 22286765 22406545 22439866 22514743 22796940 22945800 23140366 23869868 8844971 9157999 9618481
ZEB1 SOX2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
RAD18 CDH2 â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
POLB PROM1 â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368