Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
KAT7 POLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TLE1 POLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
POLB WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POLB NEIL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16982218 15260972
STUB1 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18313385
RECQL4 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19567405
PCNA UNG â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PCNA FEN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
PCNA XPC â—¼   COLOCALIZATION 2.0 0.8 intact 19279666 7263364
FEN1 POLD2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
EP300 RECQL4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19299466
RECQL4 FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19567405
RECQL4 APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19567405
RAD9A CLSPN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20424596 7897378
GNAI1 GNG2 â—¼   PROXIMITY 2.0 0.8 intact 8189321 21552208
MYC H2BC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
VIM ABLIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
S100A10 AHNAK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AHNAK DOCK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
WFS1 AKR1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18208837 7534297
APLF PARP2 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
ATF2 PCK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11042264
BCKDHB BCKDHA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12902323 5216602
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
CDCA7 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VIM CENPU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PARP1 CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
XPC CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
WFS1 CRIPT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EP300 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20339243 21467818
EP300 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20428248
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
WFS1 EPS8L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FEN1 POLD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
FEN1 TDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
POLD1 FEN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
FEN1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
FEN1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
RPA1 FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592449
SP1 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15158147 19302822
WFS1 FTL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PARP2 HMGN2 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
WFS1 HNRNPDL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC HNRNPDL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12695333
TCF3 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22564737 17490644
STUB1 LIG3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18313385
MPP1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MRFAP1 WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NDUFA4 PARP2 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
SP1 NES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15135078 19245830
POLD1 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 10852724
WRN POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10781066
TLE1 RNF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
WFS1 RNF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPA2 TLE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
WFS1 SPRY4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18313385
WFS1 TCEAL8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
XRCC1 TDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19851285 7542621
APLF CHD1L â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
POLB ALDOC â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
RECQL4 RBM3 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
POLB COA6 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
POLB HMGN2 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
APEX1 EP300 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
POLB DNAJA1 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
HUWE1 PCNA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22203964 25147182 27146073
POLB TATDN1 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
POLB SATB1 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
PARP2 CRIPT â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
RECQL4 CRIP1 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
POLD2 POLD3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
POLB SDHAF2 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
RECQL4 EPHA1 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
POLB TACC2 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
MT-CO2 NDUFA4 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
XPC VAT1L â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
BRCA1 APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 34079125
EP300 ATF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24069158 10327051
CHD1L XPC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC KAT7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC SSRP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
XPC PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SSRP1 XPC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PARP1 ERVH48-1 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
POLB GNAI1 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
POLB CENPE â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
RECQL4 WNT3 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
COX5B COX7A2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
COX6A1 COX7A2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
POLB PPAT â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
POLB EPS8L2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
POLB SATB2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
POLB NRK â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
POLB RUFY1 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
PCNA UHRF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26496610 30357346
CHD1L APLF â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23926104 26186194 28514442 19661379
APLF SSRP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
APLF XPC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CHD1L PARP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19666485 28514442 33961781
MMGT1 EMC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26496610 27342126 32439656 26186194 28514442 22119785
POLB COX7A2 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
POLB TPM4 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
POLB SAPCD2 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
POLB POLG2 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
COX6A1 NDUFA4 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
POLB CAT â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
FEN1 WRN â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
RAD9A PCNA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12400013 16189514 11994305
PARP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 34079125 26831064 25252691
FEN1 RAD9A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19535328 16216273
POLB GPATCH11 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
POLB MORF4L1 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
POLB FAH â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
POLB DDX43 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
FEN1 POLD2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
FEN1 POLD3 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
POLB ACSL1 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
COX5B NDUFA4 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
UNG EPHA1 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
POLB CSRP1 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
PARP1 UHRF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31964471 24782312 34079125
COX7A2 NDUFA4 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
FEN1 HUS1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19535328 16216273 30184152
SUPT16H SSRP1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5218941 16902406
POLB UHRF1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
POLB ERVH48-1 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
POLB NEXN â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
BRCA1 WRN â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
POLB TBC1D4 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
HUS1 PCNA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11077446 16189514
PCNA APEX1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10559261 11601988 16189514
BRCA1 CLSPN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15096610 22863316 16713569
XRCC1 APLF â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 23178593 8412483
RAD1 FEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19535328 16216273 30184152 15556996
MYC HUWE1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16269333 31677785 29467282 26279298 17314511 18488021
SSRP1 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 34079125
RECQL4 LIMD2 â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
POLB OLFM2 â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
PARP2 VIM â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
POLB SLC35A4 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
POLB DPP7 â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
CLSPN RAD9A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20424596 12766152
PARP2 APLF â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 21812934 26186194
SP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12706836 14710355 16713569 10720440 17766039
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
FEN1 RAD1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PARP2 HMGN2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 21812934
XPC PARP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 34079125 28760956
WRN CLYBL â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
APLF PARP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
POLB RHPN2 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
MORF4L1 MORF4L2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
POLB APOC1 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
POLB CRIPT â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
POLB SVBP â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
XPC WNT3 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
WRN MORF4L1 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
POLB KDM3A â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
CHD1L PARP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
POLB AKR1A1 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
POLB B3GALT6 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
BRCA1 RPA1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
POLD2 POLD1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 31449058
FEN1 APEX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11601988 16189514
SP1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10651903 34252870 16478997 11030335 11517158 15647279 17623675 17906698 28425985 32115405 31536933 12200149 24530506 23714681 10362258 22415975 16734381 19062177 10899165
PARP1 HMGB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28190768 29721183 34079125
NEIL1 XRCC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 15260972 16713569
WRN PARP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14596914 14734561
PARP2 PARP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12217960 11948190 19629035
APLF XRCC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
POLB FBXL6 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
GNAI1 GNG4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
POLD1 RPA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
POLB IREB2 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
PNKP XRCC1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
POLB RANBP6 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
BCKDHA BCKDHB â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
UHRF2 PCNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27114453 28951215 21952639
MCL1 PCNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10978339 26030842
XRCC1 APEX1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28986522 19934257 11707423 16713569
PARP1 APLF â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 17396150 18172500 20098424 28514442 27067600
POLB IQGAP3 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
POLB RCN3 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
POLB XRCC1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
MORF4L1 MRFAP1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
POLB CRIP1 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
POLB QPRT â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
POLB MPP1 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
MYC POLB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
WRN PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12633936 12750383 16713569 10871373 20600238
XRCC1 PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30260704 20227374 16713569 34111398 15107487
MYC POLD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
POLD2 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16000169 10852724 16510448
SP1 CAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12538496 11479230
MYC AKR1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
EP300 APEX1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20856196 19934257 14633989 30110629 20808282
SP1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2145272 12760745
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
MYC CRIPT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CTSF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
EP300 FEN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11430825 16326861 20019387
MYC FAH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC HMGN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333 11085504
RAD9A HUS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26088138 14624239 14681455 12628935 9872989 11907025 32296183 10777662 10852904 19464297 11994305 28514442 16189514 15314187 11340080 10359610 26186194 14611806
MCL1 HUWE1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20023629 21507240 27517746 29799788 21907705 32378766 22552282 16213503 21730980 15989957 21613222 34314700 20007713 25147182 19148187 28193319 21298030
VIM KAT7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC SLC4A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RBM3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
NEIL1 PNKP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16982218 15260972 11163244
XRCC1 NEIL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16982218 15260972 11163244
XRCC1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24778456 18971944 12897160 15555565 30260704 34079125 14500814 16713569 9584196 20302655 34111398 15044383 20303835
SP1 SERPINE2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8268720 21436258 8764573
POLB CDCA7 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
POLB MT1E â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
RECQL4 NES â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
PARP2 FLNC â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
RPA2 RPA3 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
COX6A1 MT-CO2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
XPC SPP1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
POLB PARP14 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
POLD2 POLD4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
SSRP1 SUPT16H â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TLE1 HMGB1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 16189514 11748221
RPA3 RPA2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24126761
AHNAK S100A10 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
POLD3 POLD4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RECQL4 ACAD10 â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
EP300 TCF3 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
MORF4L2 MRFAP1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
POLB DUS3L â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
RPA1 WRN â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
RECQL4 MT1G â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
POLB MYH14 â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
POLB ID1 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
PCNA UHRF2 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
COX5B COX6A1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
POLB SAMHD1 â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
POLB GAP43 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
POLB PHGDH â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
UNG MT1E â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
RPA2 UNG â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
POLB MORF4L2 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
POLB ZNF593 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
GNAS GNG2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
ID1 TCF3 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
POLB FLNC â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
FEN1 POLD1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
WRN MCL1 â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
POLB S100A10 â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
POLB PTGR2 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
RECQL4 DOCK11 â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
RAD9A RAD1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11907025 25091155 33961781 25602520 10777662 16189514 15314187 26088138 10852904 11340080 10359610 11994305 11572977 26186194 12628935 14611806 28514442 9872989
EMC2 MMGT1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
LIG3 XRCC1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
POLB KYAT1 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
RECQL4 ACTN3 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
WRN RPUSD4 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
HUWE1 MCL1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
GNAI1 GNG2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPA1 RPA3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
POLB ACBD7 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
LIG1 PCNA â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
BCKDHA BCKDHB â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
POLB ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
POLB SCD â—¼   KO_UP_REGULATES ✅ + 0.99 0.99 PKG 28854368
PCNA RPA1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HUS1 RAD9A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RAD1 RAD9A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
WRN ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
UNG MT1G â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
POLD1 POLD4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FEN1 PCNA â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLD2 POLD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPA1 RPA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLB GNAS â—¼   KO_UP_REGULATES ✅ + 0.99 0.99 PKG 28854368
COX5B MT-CO2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
COX7A2 MT-CO2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SSRP1 SUPT16H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PARP1 POLB â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10858306 11163244 11283614 11756412 11948190 12032095 12202749 12637553 14624239 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18087292 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 1974050 19748837 19772495 19847258 20027199 20064462 20211143 20227374 20478261 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22021614 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23414611 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PCNA POLB â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 16442856 16697054 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP2 POLB â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
WRN POLB â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
XRCC1 POLB â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
POLB POLD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLB FEN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21183466 19778542 20573551 11440997 15731342 6278323 15193131
POLB RPA3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLB POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLB RPA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLB PCNA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLB POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLB POLD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLB LIG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9685411 12200445 19329425 8663274 11554294
POLB RPA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
PARP2 POLB â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
PCNA POLB â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 16442856 16697054 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 POLB â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10858306 11163244 11283614 11756412 11948190 12032095 12202749 12637553 14624239 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18087292 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 1974050 19748837 19772495 19847258 20027199 20064462 20211143 20227374 20478261 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22021614 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23414611 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
XRCC1 POLB â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
WRN POLB â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
XRCC1 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15107487 26186194 8978692 16442856 15520167 11467963 26496610 15367657 25423885 16713569
APC POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15548520 17176113
RPA2 PCNA â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA POLD4 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA WRN â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 10858306 11283614 11585362 11756412 11948190 12202749 12637553 14624239 14726013 15385537 15703371 15871698 16216273 16442856 16449207 16697054 17055429 17116323 17426133 17599061 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19748837 19847258 20027199 20056333 20064462 20691907 20713526 20955519 21376743 21727086 2191300 21922195 22021614 22455312 22657828 22743550 22973052 23082994 23110144 23161013 23253856 23414611 23485469 24036544 24050180 24709898 9407949
PCNA FEN1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
PCNA POLD2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA XRCC1 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA POLD1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA CLSPN â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA BRCA1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA POLD3 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
RPA2 PCNA â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA FEN1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
PCNA CLSPN â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA POLD1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA POLD3 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA POLD4 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA WRN â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 10858306 11283614 11585362 11756412 11948190 12202749 12637553 14624239 14726013 15385537 15703371 15871698 16216273 16442856 16449207 16697054 17055429 17116323 17426133 17599061 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19748837 19847258 20027199 20056333 20064462 20691907 20713526 20955519 21376743 21727086 2191300 21922195 22021614 22455312 22657828 22743550 22973052 23082994 23110144 23161013 23253856 23414611 23485469 24036544 24050180 24709898 9407949
PCNA POLD2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA XRCC1 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA BRCA1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
HUS1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11077446 16189514
LIG1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12171929 9649448 28073635 10559261
PCNA NEIL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18032376
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
PCNA FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 28514442 15576034 8668533 3113402 11601988 12853968 31467278 1477073 24958773 7673186 16216273 11313979 15616578 8876181 14657243 11430825 26496610 16189514 9305916 22606318 28073635 19153658 26751069 26186194 9178907 22592530 24728180 17115032 18692475 26030842 16326861 29997244 22556262 9545252 31515488
PCNA POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24022480 9038370 16510448
RPA2 LIG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
PARP1 LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
LIG1 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
LIG1 POLD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
LIG1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
LIG1 RPA3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
LIG1 POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
LIG1 RPA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
LIG1 POLD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
PARP1 LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
POLD4 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
APEX1 POLD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLD1 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD4 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD2 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD2 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 9286699 12403614 16510448
RPA3 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA3 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA3 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
MYC APC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22911891 12695333
APC FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15548520 17176113
UNG APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9724657 15479784 25086253 9200707
PARP1 APEX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 17548475 11440997 12727891 15135726 10364231 11340072 9804757
RPA2 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
RPA1 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 RPA3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
MYC APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14519204 11983916 12695333 11085504
EP300 APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14633989 20856196 20711647
FEN1 APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11601988 16189514
APLF PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18172500 17396150 20098424
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 PARP2 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 XRCC3 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 PARP2 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 XRCC3 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 XPC â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
SP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15252835 17373631 18377656 19466541
PARP1 CHD1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22146311 19666485
MT-CO2 COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
MT-CO2 COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19608861 11430825
WRN FEN1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
PARP1 FEN1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
POLD1 FEN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
RPA2 FEN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
RPA1 FEN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
RPA3 FEN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
WRN FEN1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
WRN FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 14657243 12356323 11598021 16326861 10893179 14688284
HUS1 RAD1 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 15871698 16216273 16697054 16713580 16731526 16805667 16879101 16885023 17102137 17116885 17129768 17296725 17303408 17384638 17395641 17426133 17493829 17582221 17855402 18469862 18543256 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 23507534 8943031 9524127
HUS1 NEIL1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 15459660 15703371 16697054 16879101 17395641 17493829 19847258 8943031 9524127
HUS1 RPA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
HUS1 RAD1 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 15871698 16216273 16697054 16713580 16731526 16805667 16879101 16885023 17102137 17116885 17129768 17296725 17303408 17384638 17395641 17426133 17493829 17582221 17855402 18469862 18543256 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 23507534 8943031 9524127
HUS1 NEIL1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 15459660 15703371 16697054 16879101 17395641 17493829 19847258 8943031 9524127
HUS1 RPA3 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RPA1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RPA2 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUWE1 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 32378766 15989957 21507240 20023629 28939105 16543145 16213503
HUWE1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26279298 16915296 34761308 16969074
SP1 ID1 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
TCF3 ID1 â—¼   UP_REGULATES ✅ + 7.0 1.0 ACSN 15169839 16831886 17018611 17299729 17490644 18832382 22564737
WRN LIG3 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 11283614 11900249 12202749 12648680 14726013 15385537 15703371 16449207 16697054 17055429 17116323 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19362533 19490890 19809470 19847258 20027199 20056333 20064462 20211143 20691907 20713526 21376743 2191300 22657828 22743550 23082994 23161013 23253856 24036544 24050180 24709898
XRCC1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 LIG3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
LIG3 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9705932 20227374 17353931 11163244 26496610 16713569 8264637 11352725 9136882
SP1 MCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22406829 18599869 17198743 22734486 18208354 23877711
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC PPAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14519204 18628958 12695333
TCF3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
RAD1 NEIL1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 15459660 15703371 16697054 16879101 17395641 17493829 19847258 8943031 9524127
RAD1 NEIL1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 15459660 15703371 16697054 16879101 17395641 17493829 19847258 8943031 9524127
WRN NEIL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17611195 20346739
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 PARP2 â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 18835851 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21037379 21060331 21076181 21270334 21337561 21376743 21818122 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 WRN â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15211575 15385537 15385968 15498778 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19654615 19748837 19847258 19892829 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24089143 24095737 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 WRN â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15211575 15385537 15385968 15498778 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19654615 19748837 19847258 19892829 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24089143 24095737 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 WRN â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15211575 15385537 15385968 15498778 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19654615 19748837 19847258 19892829 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24089143 24095737 24210699 24684389 24709898 24976506 8264637 8978692
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
PARP1 SUPT16H â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18406329 16682447
XRCC1 PARP2 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
WRN PARP2 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
XRCC1 PARP2 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
WRN PARP2 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
XRCC1 PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21637298 17353931 11163244 28821613 19155274 15367657 15385968 26496610 16713569
POLD4 POLD1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD4 POLD1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12403614 16510448
POLD4 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD4 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
RAD1 RPA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RAD1 RPA2 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 RPA1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 RPA3 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA3 RAD9A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RPA1 RAD9A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RPA2 RAD9A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RPA2 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 14499497 24126761 24332808 10373438 15735006 15965237 26474068 14734561
RPA2 XRCC1 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 RPA3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 XRCC1 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
RPA2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
SP1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24240095 11126367 17689681
SP1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17663720 22227038 3419902 10777586 12771217
WRN XRCC1 â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
WRN XRCC1 â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
POLB PTER â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
WRN RANBP6 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
POLB TTC9 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
RECQL4 KDM3A â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
POLB RNF10 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
POLB MT-CO2 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
WRN NDUFA4 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
WRN PHYH â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
PARP2 NDUFA4 â—¼   KO_DOWN_REGULATES ✅ - -1.03 1.02 PKG 28854368
WRN ASMTL â—¼   KO_DOWN_REGULATES ✅ - -1.03 1.02 PKG 28854368
POLB FTL â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
POLB RPUSD4 â—¼   KO_UP_REGULATES ✅ + 1.03 1.03 PKG 28854368
POLB GNG2 â—¼   KO_UP_REGULATES ✅ + 1.03 1.03 PKG 28854368
POLB CD40 â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
POLB MACC1 â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
POLB RBM3 â—¼   KO_UP_REGULATES ✅ + 1.03 1.03 PKG 28854368
POLB CTSF â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
RECQL4 VIM â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
POLB SNCG â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
POLB SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
POLB HMGCR â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
RECQL4 FLNC â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
POLB ASRGL1 â—¼   KO_UP_REGULATES ✅ + 1.05 1.05 PKG 28854368
POLB GCAT â—¼   KO_DOWN_REGULATES ✅ - -1.06 1.05 PKG 28854368
RECQL4 RNASET2 â—¼   KO_UP_REGULATES ✅ + 1.06 1.06 PKG 28854368
POLB TSPYL1 â—¼   KO_UP_REGULATES ✅ + 1.06 1.06 PKG 28854368
POLB APOOL â—¼   KO_DOWN_REGULATES ✅ - -1.07 1.06 PKG 28854368
UNG SPP1 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
POLB GNG4 â—¼   KO_DOWN_REGULATES ✅ - -1.09 1.08 PKG 28854368
XPC LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.08 1.08 PKG 28854368
POLB AHNAK â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
WRN MT-CO2 â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
PARP2 SPP1 â—¼   KO_DOWN_REGULATES ✅ - -1.1 1.09 PKG 28854368
XPC MT1G â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
POLB SOX3 â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368
RECQL4 PHYH â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
POLB FGF2 â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
POLB MMADHC â—¼   KO_UP_REGULATES ✅ + 1.11 1.11 PKG 28854368
XPC NRK â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
POLB CGNL1 â—¼   KO_DOWN_REGULATES ✅ - -1.13 1.12 PKG 28854368
POLB CLSPN â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
WRN CENPE â—¼   KO_UP_REGULATES ✅ + 1.13 1.13 PKG 28854368
POLB TMEM131 â—¼   KO_UP_REGULATES ✅ + 1.14 1.14 PKG 28854368
UNG CRIPT â—¼   KO_DOWN_REGULATES ✅ - -1.15 1.14 PKG 28854368
POLB EPHA1 â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
POLB RNASET2 â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
POLB AMT â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
POLB DCAF11 â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
POLB ZDHHC22 â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
POLB ACYP1 â—¼   KO_DOWN_REGULATES ✅ - -1.18 1.17 PKG 28854368
POLB HOMER3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
RECQL4 SCD â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
WRN HMGCR â—¼   KO_UP_REGULATES ✅ + 1.18 1.18 PKG 28854368
XPC MT1E â—¼   KO_UP_REGULATES ✅ + 1.19 1.19 PKG 28854368
POLB ACTN3 â—¼   KO_DOWN_REGULATES ✅ - -1.2 1.19 PKG 28854368
XPC AKAP2 â—¼   KO_DOWN_REGULATES ✅ - -1.21 1.2 PKG 28854368
POLB COX6A1 â—¼   KO_UP_REGULATES ✅ + 1.21 1.21 PKG 28854368
POLB MRFAP1 â—¼   KO_UP_REGULATES ✅ + 1.22 1.22 PKG 28854368
RECQL4 SLC16A3 â—¼   KO_UP_REGULATES ✅ + 1.22 1.22 PKG 28854368
POLB ASMTL â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
RECQL4 NRK â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
POLB SLC4A2 â—¼   KO_UP_REGULATES ✅ + 1.23 1.23 PKG 28854368
POLB PCK2 â—¼   KO_DOWN_REGULATES ✅ - -1.26 1.25 PKG 28854368
POLB PROM1 â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
PARP2 MT1E â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
POLB CA8 â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
RECQL4 SPP1 â—¼   KO_DOWN_REGULATES ✅ - -1.28 1.27 PKG 28854368
POLB PHYH â—¼   KO_DOWN_REGULATES ✅ - -1.3 1.29 PKG 28854368
XPC CAT â—¼   KO_UP_REGULATES ✅ + 1.29 1.29 PKG 28854368
POLB SLC16A10 â—¼   KO_DOWN_REGULATES ✅ - -1.3 1.29 PKG 28854368
POLB CBR1 â—¼   KO_DOWN_REGULATES ✅ - -1.31 1.3 PKG 28854368
POLB PLSCR3 â—¼   KO_DOWN_REGULATES ✅ - -1.31 1.3 PKG 28854368
RECQL4 CLSPN â—¼   KO_DOWN_REGULATES ✅ - -1.32 1.31 PKG 28854368
POLB DOCK11 â—¼   KO_DOWN_REGULATES ✅ - -1.32 1.31 PKG 28854368
POLB WNT3 â—¼   KO_UP_REGULATES ✅ + 1.32 1.32 PKG 28854368
POLB IFI30 â—¼   KO_DOWN_REGULATES ✅ - -1.33 1.32 PKG 28854368
POLB MCL1 â—¼   KO_UP_REGULATES ✅ + 1.34 1.34 PKG 28854368
POLB GPR50 â—¼   KO_UP_REGULATES ✅ + 1.35 1.35 PKG 28854368
POLB COX5B â—¼   KO_UP_REGULATES ✅ + 1.35 1.35 PKG 28854368
RECQL4 AHNAK â—¼   KO_DOWN_REGULATES ✅ - -1.37 1.36 PKG 28854368
POLB NES â—¼   KO_UP_REGULATES ✅ + 1.37 1.37 PKG 28854368
PARP2 TAGLN â—¼   KO_DOWN_REGULATES ✅ - -1.38 1.37 PKG 28854368
POLB GSDMD â—¼   KO_DOWN_REGULATES ✅ - -1.39 1.38 PKG 28854368
WRN SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.4 1.39 PKG 28854368
POLB CENPU â—¼   KO_UP_REGULATES ✅ + 1.41 1.41 PKG 28854368
POLB TCEAL8 â—¼   KO_UP_REGULATES ✅ + 1.41 1.41 PKG 28854368
POLB NDUFA4 â—¼   KO_UP_REGULATES ✅ + 1.44 1.44 PKG 28854368
POLB SPRY4 â—¼   KO_UP_REGULATES ✅ + 1.45 1.45 PKG 28854368
POLB MT1G â—¼   KO_UP_REGULATES ✅ + 1.52 1.52 PKG 28854368
POLB CLYBL â—¼   KO_DOWN_REGULATES ✅ - -1.53 1.52 PKG 28854368
POLB ARHGEF18 â—¼   KO_DOWN_REGULATES ✅ - -1.53 1.52 PKG 28854368
POLB GNAO1 â—¼   KO_DOWN_REGULATES ✅ - -1.54 1.53 PKG 28854368
POLB SERPINE2 â—¼   KO_UP_REGULATES ✅ + 1.53 1.53 PKG 28854368
POLB LCK â—¼   KO_DOWN_REGULATES ✅ - -1.56 1.55 PKG 28854368
WRN MPP1 â—¼   KO_DOWN_REGULATES ✅ - -1.56 1.55 PKG 28854368
POLB HNRNPDL â—¼   KO_UP_REGULATES ✅ + 1.55 1.55 PKG 28854368
POLB TAP1 â—¼   KO_DOWN_REGULATES ✅ - -1.57 1.56 PKG 28854368
POLB AKAP2 â—¼   KO_DOWN_REGULATES ✅ - -1.6 1.59 PKG 28854368
POLB LIMD2 â—¼   KO_UP_REGULATES ✅ + 1.6 1.6 PKG 28854368
WRN TSPYL1 â—¼   KO_UP_REGULATES ✅ + 1.61 1.61 PKG 28854368
POLB ABLIM1 â—¼   KO_UP_REGULATES ✅ + 1.63 1.63 PKG 28854368
POLB TAGLN â—¼   KO_UP_REGULATES ✅ + 1.68 1.68 PKG 28854368
RECQL4 LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -1.71 1.71 PKG 28854368
POLB RAB12 â—¼   KO_DOWN_REGULATES ✅ - -1.74 1.73 PKG 28854368
POLB LEFTY1 â—¼   KO_UP_REGULATES ✅ + 1.88 1.88 PKG 28854368
POLB SORBS2 â—¼   KO_DOWN_REGULATES ✅ - -1.91 1.9 PKG 28854368
RECQL4 FGF2 â—¼   KO_DOWN_REGULATES ✅ - -1.95 1.94 PKG 28854368
WRN ACYP1 â—¼   KO_DOWN_REGULATES ✅ - -2.02 2.01 PKG 28854368
PARP1 TAGLN â—¼   KO_DOWN_REGULATES ✅ - -2.06 2.05 PKG 28854368
POLB SPP1 â—¼   KO_UP_REGULATES ✅ + 2.17 2.17 PKG 28854368
PARP2 LEFTY1 â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.24 PKG 28854368
POLB VAT1L â—¼   KO_UP_REGULATES ✅ + 2.29 2.29 PKG 28854368
POLB CHD1L â—¼   KO_DOWN_REGULATES ✅ - -2.33 2.32 PKG 28854368
RECQL4 DDX43 â—¼   KO_DOWN_REGULATES ✅ - -2.5 2.49 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
RECQL4 TAGLN â—¼   KO_DOWN_REGULATES ✅ - -3.05 3.04 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
POLB VIM â—¼   KO_UP_REGULATES ✅ + 3.54 3.54 PKG 28854368
XPC HIST1H1A â—¼   KO_DOWN_REGULATES ✅ - -3.58 3.57 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
POLB HIST1H1A â—¼   KO_DOWN_REGULATES ✅ - -3.69 3.68 PKG 28854368
UNG UNG â—¼   KO_DOWN_REGULATES ✅ - -5.41 5.4 PKG 28854368
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368
POLB RPS4Y1 â—¼   KO_DOWN_REGULATES ✅ - -8.0 7.99 PKG 28854368
XPC RPS4Y1 â—¼   KO_DOWN_REGULATES ✅ - -11.64 11.63 PKG 28854368