Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
HSPD1 NLRP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
TP53 UBE2A â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
SKP1 ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 23770852
MYC PNO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 29467282
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
SKP1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 9858587 33422522 26496610 16209941
CUL1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16209941 33422522 26496610 21145461
POLB FBXL6 â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CDK4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MYC CDK4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 21988832 28628118
MYC SKP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12963825 29467282 30415952 21988832 17314511
MYC POLB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
TP53 KBTBD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
SKP1 FBXL6 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 32576198 27705803 19159283
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
TP53 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16931621 8270002 9275177 19671680 16571800 8641461 9360984 21952947
MYC CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8386381 10713672 12835716 7608142 12937171 14519204 14729654
CCNA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14640983 10884347 16713569
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
MYC HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19022255 12695333 14519204 21995449 11983916 11085504
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
XRCC4 FBXL6 â—¼   KO_UP_REGULATES ✅ + 1.38 1.38 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368