Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
VIM XRCC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHD3 XRCC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H1-1 XRCC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
XRCC4 ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
XRCC4 PNKP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15385968 5217205
XRCC4 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15380105 5217198
XRCC4 CAAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC4 CSNK2A1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15385968 5217205
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SUMO1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16478998
DCLRE1C XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16857680
MRE11 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
MRE11 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
MRE11 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RAD50 MRE11 â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
CSNK2A1 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28436950
PRKDC H1-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18250087
PAXX XRCC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1261971 25574025
SPP1 ABCF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM ABLIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VIM CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
NFKB1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19027835
CSNK2A1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20711232
RAD50 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
NBN DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
VIM DPPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ERG VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8895512
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
ERG FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12137767
MYC FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20638938 19366810
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
NBN SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
NBN UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
RAD50 NBN â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
NFKB1 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9762895
NHEJ1 XRCC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SUMO1 RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
UBE2I RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
TDG SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218717 16763556
VIM WEE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
XRCC4 ALPL â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
XRCC4 DEF6 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
XRCC4 SQSTM1 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
XRCC4 AIP â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
TDG CFDP1 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
XRCC4 TERF2 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
XRCC4 JADE2 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
XRCC4 TMLHE â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
XRCC4 TJP3 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
XRCC4 NDUFA4 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
XRCC4 CDCA7 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
XRCC4 DIDO1 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
NHEJ1 PRAF2 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
XRCC4 NTHL1 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
XRCC4 SLC25A29 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
PRKDC CYP27A1 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
RN135 XRCC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UIF XRCC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FA60A XRCC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PRKDC MRE11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10608806 20808282
MRE11 NBN â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
CHD3 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30585729 28977666
MYC PRKDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RAD50 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC TDG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 26496610
MYC XRCC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
NFKB1 PRKDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 14743216
XRCC4 PLSCR3 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
APTX XRCC4 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
XRCC4 FAM129A â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
XRCC4 AKT2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
XRCC4 PGM1 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
XRCC4 MPST â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
XRCC4 C6orf132 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
PAXX PYGL â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
TDG CDH2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
XRCC4 GNG7 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
XRCC4 LONF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
XRCC4 FAM9B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25416956 32296183
XRCC4 IFFO2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
XRCC4 NFKB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
XRCC4 AL7A1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
XRCC4 APBP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
XRCC6 DNLI4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22990118 15520013 10757784 26496610
XRCC4 MMADHC â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
XRCC4 GPC4 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
APLF XRCC4 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
XRCC4 SDHA â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
XRCC4 TSEN2 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
CDC6 FBXW7 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
XRCC4 KCTD12 â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
TDG CBR3 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
BLM RAD50 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
XRCC4 PHYH â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
NHEJ1 FADS2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
FBXW7 MCL1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
XRCC4 URM1 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
XRCC4 TK1 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
TDG LIMD2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
NBN SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
XRCC4 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9430729 15194694 22939629 9259561 15520013
SUMO1 ACTN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15576338 19596686
RAD50 BLM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25084169 10783165 29523790
BLM MYC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30415952 29467282 23750012
XRCC4 ABLIM1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
XRCC4 SARAF â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
XRCC4 CDK18 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
PAXX CDCA7 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
PAXX TWSG1 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
XRCC4 PLD3 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
PNKP DNLI4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15385968 17353931
NBN BLM â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10783165 29523790
XRCC4 NUFIP1 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
XRCC4 ZNF593 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
XRCC4 MFAP2 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
NHEJ1 TDG â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
XRCC4 MARCKS â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
XRCC4 PDZD4 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
XRCC4 RRM2 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
XRCC4 HIST1H1D â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
RAD50 TERF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
PRKDC XRCC4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
APLF LIG4 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
LIG4 XRCC6 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
XRCC4 CLYBL â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
LIG4 NHEJ1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DCLRE1C PRKDC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
POLM CBR3 â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
XRCC4 PCCA â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
TERF2 XRCC6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MRE11 BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10783165 28506294 29523790
PRKDC DNLI4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22529269 10608806 15194694
CDC20 UBE2S â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
PRKDC ERG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24591637 21575865
XRCC4 ATP2B4 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
XRCC4 CORO7 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
XRCC4 HS1BP3 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
GOSR2 STX6 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
XRCC4 ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
TERF2 MRE11 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18212065 22939629 10888888 19287395
MRE11 XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30585729 10508516 26344197
APLF DNLI4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 17396150 26186194 23178593 28514442
MYC XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282
TERF2 NBN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22939629 10888888 19287395
XRCC6 TERF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10984620 26496610 21044950
XRCC4 HSPG2 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
IFFO1 XRCC4 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
PAXX RRM2 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
NHEJ1 TSPYL1 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
XRCC4 CYP27A1 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
XRCC4 CACNA2D2 â—¼   KO_DOWN_REGULATES ✅ - -0.9 0.89 PKG 28854368
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
XRCC4 DNLI4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 11702069 15520013 22658747 10757784 9705934 10854421 11809878 21070942 32296183 31548606 23219551 17567543 28514442 25416956 30496552 22529269 15194694 25910212 9259561 26186194
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
NBN MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12750284 12419185 24413181 21884979 24981860 22939629 12679336 10426999 28369484 17526493 9705271 26455393 12607003 17612497 12447395 22464731 22078559 22231403 34348893 28363998 11062235 15758953 11238951 23530059 33558481 15734743 34038735 30179224 12861053 18458108 19270065 17500065 10783165 30440001 22941933 19244116
NHEJ1 DNLI4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 22658747 17567543 16439205
XRCC5 APLF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17396150 20098424 26186194 23178593 28514442
MYC BIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21447800 10380878 18348166
BLM TERF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12181313 19329795 15229185
MYC CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10899308 17093053
MYC CRAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
DALRD3 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDAH2 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ERG HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16310515 10022513
NFKB1 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19752329 8016102
MYC ICAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PRKDC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC NTHL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SLC4A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RBM3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
PLD3 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
XRCC5 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26496610 22404984 15520013 21679440 26446488 26344197 17308091 15941674 28154079 16857680 20711232 19303849 20023628 15758953 20085707 10750018 10446239 33005030 9312071 28345663 12393188
XRCC6 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8422676 20711232 19303849 26175416 28345663 30585729 17308091 22939629 26496610 10750018 15941674 33005030 21969602 15520013 10064605 21575865 26446488
TERF2 RAD50 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18212065 22939629 10888888 19287395 15100233
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
NHEJ1 DEF6 â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
NHEJ1 CDC20 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
XRCC4 TRIM5 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
XRCC4 RPUSD4 â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
POLM NDUFA4 â—¼   KO_DOWN_REGULATES ✅ - -0.92 0.91 PKG 28854368
XRCC4 DPPA4 â—¼   KO_DOWN_REGULATES ✅ - -0.92 0.91 PKG 28854368
XRCC4 UHRF1 â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
XRCC4 HMGCR â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
XRCC4 RNASET2 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
XRCC4 STX16 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
XRCC4 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
XRCC4 DDAH2 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
FBXW7 MYC â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
XRCC4 TMCO3 â—¼   KO_UP_REGULATES ✅ + 0.92 0.92 PKG 28854368
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
XRCC4 TXNL4B â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
NHEJ1 XRCC5 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
POLM SCD â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
NHEJ1 CLIP2 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
NBN RAD50 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
XRCC4 DOHH â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
NHEJ1 JADE2 â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
NHEJ1 STX6 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
NHEJ1 NUFIP1 â—¼   KO_UP_REGULATES ✅ + 0.94 0.94 PKG 28854368
XRCC4 REEP6 â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
PAXX GLUL â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
XRCC4 DALRD3 â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
TDG POLL â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
TDG UHRF1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
XRCC4 TWSG1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
XRCC4 CAPG â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
NHEJ1 PLBD1 â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
XRCC4 FOXH1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
XRCC4 PRELID1 â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
XRCC4 TMEM68 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
BIN1 MYC â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
XRCC4 TNFRSF10B â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
XRCC4 CLSPN â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
NHEJ1 PYGL â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
NHEJ1 PTMS â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
XRCC4 EGLN1 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
FBXW7 CUL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 32086376 14603323 11585921 28007894 23108047 21205095 31285543 29408378 29103612 25143387 25720964 22405651 23322298 28522751 29695787 22388891 23453757 28514442 11565034 29499133 21145461 25515538 32350066 22524983 26976582
RAD50 NBN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 19197236 22939629 12679336 10426999 26344197 17526493 9705271 12607003 17612497 12447395 22464731 34348893 11062235 15758953 12124328 11238951 26215093 23530059 15734743 16391231 24651726 30179224 17500065 30440001 22941933 10783165
XRCC4 CRAT â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
XRCC4 PYGL â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
NHEJ1 DIDO1 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
SUMO1 TDG â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
APLF XRCC6 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
NBN TERF2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
APLF XRCC5 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
XRCC4 NDUFA7 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
XRCC4 ZNF48 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
NBN SCD â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
TDG SCD â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
XRCC4 C16orf58 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
NHEJ1 SDHA â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
XRCC4 CRIP1 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
XRCC4 L1RE1 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
NHEJ1 TWSG1 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
XRCC4 UBE2S â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
XRCC4 TRIM59 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
PAXX CRAT â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
RAD50 MRE11 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12750284 24413181 24981860 19197236 22939629 31501894 30733337 10508516 26344197 8756642 28369484 9705271 26455393 12607003 16163361 11504724 34348893 28363998 11062235 26215093 27173435 23530059 33558481 15734743 16391231 24651726 17694070 34038735 17500065 19270065 30179224 10888888 10783165
CUL1 FBXW7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
XRCC4 RANBP6 â—¼   KO_UP_REGULATES ✅ + 0.99 0.99 PKG 28854368
XRCC4 ICAM1 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC4 TRAF7 â—¼   KO_UP_REGULATES ✅ + 0.99 0.99 PKG 28854368
PARP3 LIG4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
LIG4 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
LIG4 APLF â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
LIG4 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
LIG4 XRCC4 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 11163244 12032095 12471202 15385968 15703371 16439205 16697054 17088286 17638872 18077224 19346677 19473888 19546231 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PARP3 LIG4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
LIG4 APLF â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
LIG4 XRCC4 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 11163244 12032095 12471202 15385968 15703371 16439205 16697054 17088286 17638872 18077224 19346677 19473888 19546231 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PRKDC LIG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15194694 15941674 17570479
PARP3 XRCC4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
XRCC4 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC4 DCLRE1C â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC4 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC4 APLF â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PARP3 XRCC4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
XRCC4 APLF â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
XRCC4 PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 21637298 26186194 17353931 12032095 32296183 15385968
CSNK1D UHRF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23297342
CLSPN CDC6 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDC6 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDC6 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
NFKB1 CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
CUL1 WEE1 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
CUL1 PDCD4 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17053147 17884153 18931676 19270156 19622404 19686080 19797085 19809470 19847258
XRCC5 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RAD50 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19197236 16163361 10888888 8756642 17713585
MRE11 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 22464731 26455393 12861053 17500065 15734743 12419185 19270065 22078559 19244116 21884979 12679336 11238951 12607003 9705271 17713585 10783165 12447395 10426999 18458108 15758953
PTK2 ACTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 25860875 20159040 11369769 20940419 16291744 23454549 19229129
PARP3 APLF â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PARP3 APLF â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PTK2 ATP2B4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25847233 9182531 12540962
BLM TERF2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 23253856 24089143 24095737
BLM RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
TERF2 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 15229185 19329795 12181313
CSNK1D CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10500146
CDK5 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11160818 21825040 21378178 14712065 25525271 24091658 17096371 33999101 23294285 24121667 33981002 17185424 28361970 12941275 20519501
CSNK2A1 MME â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22767595 20957047
XRCC5 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
XRCC6 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
DCLRE1C POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
DCLRE1C POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
DCLRE1C NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC DCLRE1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17242184 15723659 11955432 16600297 23163657 22529269 16874298 21641068 19423708 15936993 1660029
ERG ICAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22235125 22337883 20966395
FBXW7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15498494 17145710 32047362 28007894 31569395 33821962 20399964 20970423 17157259 16023596 20852628 15103331 15150404
GLUL PYGL â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
GLUL PYGL â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
GLUL PYGL â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 11274345 16469705 17603935 18641653 19037093 19498109 19524512 19524513 19632174 20823910 20861672 21133840 21232017 22265414 22421439 23010170 23073834 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 27558815 27833036 27959630 28498367 28574505 28645028
PRKACA HMGCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 2369897
MYC HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333 10600159
NFKB1 ICAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 10926553 15480988 9192770 7957928 11198351 19074768 9188493 16317091 17121934 18928584 15843586 22001597 9056676 18285351 16385502 10946302 20103608 10738944 15800027 22708120 9888295 11877286 17855547 10553096 10092659 9733827 11401521 11463837 9916895 20173029 10837365 12691701 16105834 12490396 16453001
PRKDC MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11749722 16319174
MAPK8 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12223490 20696142 17463001 17670986 18676833 26538579
MAPK8 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19651622 10551811 17081983 18767875 20068231 91332050 1651323 1748630 16713569 11243879 18669648 15210690
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
NBN XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NDUFA7 NDUFA4 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFA7 NDUFA4 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
PRKACA NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
NFKB1 TNFRSF10B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18523266 18599488 19351839
PRKACA NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19531803 12947093 17959673 15642694 15197457
XRCC5 NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC6 NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
NHEJ1 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
NHEJ1 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23433795 21824916 24000320
XRCC5 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC6 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC6 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC5 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKACA VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 36.0 1.0 Omnipath 14762106 20058876 11895474 19007248 23737341 19691289 28117759 18669648 18767875 2500966 20068231 19144319 17287340 12761892 22345628 19664995 18212344
XRCC5 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
SUMO1 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 16763556 15959518 17060459 21284855 20504299 16189514 16524884 11889051 10961991
UBE2I TDG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15823533 18691969 21284855 15959518 11889051
UBE2I TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18512959 24753249 18691969
XRCC4 ACO1 â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
XRCC4 PCIF1 â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
PAXX ECHDC3 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
NHEJ1 KIF18B â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
NHEJ1 PDZD4 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
XRCC4 HMOX1 â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
TDG FGF2 â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
XRCC4 GLUL â—¼   KO_UP_REGULATES ✅ + 1.02 1.02 PKG 28854368
XRCC4 STX6 â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
XRCC4 NUDT5 â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
PAXX STX16 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
NHEJ1 GNG7 â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
XRCC4 LIMD2 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
XRCC4 HMGCS1 â—¼   KO_UP_REGULATES ✅ + 1.05 1.05 PKG 28854368
XRCC4 CDH2 â—¼   KO_UP_REGULATES ✅ + 1.06 1.06 PKG 28854368
PAXX HMGCS1 â—¼   KO_DOWN_REGULATES ✅ - -1.07 1.06 PKG 28854368
XRCC4 ZADH2 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
XRCC4 FADS2 â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
XRCC4 SLC20A1 â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
XRCC4 NCDN â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
XRCC4 AMIGO3 â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
NHEJ1 AHNAK â—¼   KO_UP_REGULATES ✅ + 1.07 1.07 PKG 28854368
NHEJ1 TERF2 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
NHEJ1 PCCA â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
NHEJ1 ACTR8 â—¼   KO_UP_REGULATES ✅ + 1.08 1.08 PKG 28854368
POLM TCF25 â—¼   KO_DOWN_REGULATES ✅ - -1.09 1.08 PKG 28854368
NHEJ1 REEP6 â—¼   KO_DOWN_REGULATES ✅ - -1.09 1.08 PKG 28854368
XRCC4 PRAF2 â—¼   KO_DOWN_REGULATES ✅ - -1.1 1.09 PKG 28854368
PAXX PDCD4 â—¼   KO_UP_REGULATES ✅ + 1.09 1.09 PKG 28854368
NHEJ1 NDUFA4 â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
NHEJ1 PDCD4 â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368
NHEJ1 PHYH â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368
XRCC4 GYG1 â—¼   KO_DOWN_REGULATES ✅ - -1.12 1.11 PKG 28854368
XRCC4 SLC4A2 â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
XRCC4 CDC20 â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
XRCC4 TCF25 â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
XRCC4 ACTR8 â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
PAXX RPL22L1 â—¼   KO_DOWN_REGULATES ✅ - -1.14 1.13 PKG 28854368
NHEJ1 SLC4A2 â—¼   KO_UP_REGULATES ✅ + 1.13 1.13 PKG 28854368
XRCC4 CLIP2 â—¼   KO_DOWN_REGULATES ✅ - -1.15 1.14 PKG 28854368
PRKDC RPL22L1 â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
NHEJ1 MME â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
XRCC4 SCD â—¼   KO_UP_REGULATES ✅ + 1.16 1.16 PKG 28854368
XRCC4 RPL22L1 â—¼   KO_UP_REGULATES ✅ + 1.17 1.17 PKG 28854368
NHEJ1 ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -1.18 1.17 PKG 28854368
POLM CCDC28A â—¼   KO_DOWN_REGULATES ✅ - -1.18 1.17 PKG 28854368
NHEJ1 SLC4A7 â—¼   KO_DOWN_REGULATES ✅ - -1.18 1.17 PKG 28854368
TDG SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
XRCC4 ABCF3 â—¼   KO_UP_REGULATES ✅ + 1.18 1.18 PKG 28854368
NHEJ1 ECHDC3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
TDG TWSG1 â—¼   KO_UP_REGULATES ✅ + 1.18 1.18 PKG 28854368
POLM RPL22L1 â—¼   KO_DOWN_REGULATES ✅ - -1.2 1.19 PKG 28854368
TDG AHNAK â—¼   KO_UP_REGULATES ✅ + 1.2 1.2 PKG 28854368
XRCC4 TWNK â—¼   KO_UP_REGULATES ✅ + 1.21 1.21 PKG 28854368
XRCC4 DHTKD1 â—¼   KO_DOWN_REGULATES ✅ - -1.22 1.21 PKG 28854368
XRCC4 SUN2 â—¼   KO_DOWN_REGULATES ✅ - -1.22 1.21 PKG 28854368
XRCC4 CDA â—¼   KO_DOWN_REGULATES ✅ - -1.23 1.22 PKG 28854368
XRCC4 CBR3 â—¼   KO_DOWN_REGULATES ✅ - -1.23 1.22 PKG 28854368
TDG PDCD4 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
NHEJ1 CLYBL â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
XRCC4 GOSR2 â—¼   KO_UP_REGULATES ✅ + 1.24 1.24 PKG 28854368
XRCC4 TSPYL1 â—¼   KO_UP_REGULATES ✅ + 1.25 1.25 PKG 28854368
XRCC4 PTMS â—¼   KO_DOWN_REGULATES ✅ - -1.26 1.25 PKG 28854368
TDG HMGCS1 â—¼   KO_UP_REGULATES ✅ + 1.25 1.25 PKG 28854368
NHEJ1 MARCKS â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
TDG REEP6 â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
XRCC4 TDG â—¼   KO_UP_REGULATES ✅ + 1.27 1.27 PKG 28854368
XRCC4 KYAT1 â—¼   KO_DOWN_REGULATES ✅ - -1.29 1.28 PKG 28854368
XRCC4 H1F0 â—¼   KO_DOWN_REGULATES ✅ - -1.3 1.29 PKG 28854368
XRCC4 ARV1 â—¼   KO_UP_REGULATES ✅ + 1.3 1.3 PKG 28854368
POLM PLBD1 â—¼   KO_UP_REGULATES ✅ + 1.32 1.32 PKG 28854368
XRCC4 MORF4L2 â—¼   KO_UP_REGULATES ✅ + 1.32 1.32 PKG 28854368
TDG RPL22L1 â—¼   KO_UP_REGULATES ✅ + 1.33 1.33 PKG 28854368
XRCC4 ZNHIT6 â—¼   KO_UP_REGULATES ✅ + 1.33 1.33 PKG 28854368
XRCC4 POLR3K â—¼   KO_UP_REGULATES ✅ + 1.34 1.34 PKG 28854368
NHEJ1 CRIP1 â—¼   KO_UP_REGULATES ✅ + 1.34 1.34 PKG 28854368
NHEJ1 PRELID1 â—¼   KO_UP_REGULATES ✅ + 1.34 1.34 PKG 28854368
XRCC4 MME â—¼   KO_UP_REGULATES ✅ + 1.35 1.35 PKG 28854368
PAXX ICAM1 â—¼   KO_UP_REGULATES ✅ + 1.37 1.37 PKG 28854368
XRCC4 RBM3 â—¼   KO_UP_REGULATES ✅ + 1.37 1.37 PKG 28854368
XRCC4 FBXL6 â—¼   KO_UP_REGULATES ✅ + 1.38 1.38 PKG 28854368
XRCC4 PLBD1 â—¼   KO_DOWN_REGULATES ✅ - -1.4 1.39 PKG 28854368
POLM MORF4L2 â—¼   KO_DOWN_REGULATES ✅ - -1.41 1.4 PKG 28854368
NHEJ1 HSPG2 â—¼   KO_DOWN_REGULATES ✅ - -1.42 1.41 PKG 28854368
POLM CDCA7 â—¼   KO_DOWN_REGULATES ✅ - -1.43 1.42 PKG 28854368
NHEJ1 DHTKD1 â—¼   KO_DOWN_REGULATES ✅ - -1.43 1.42 PKG 28854368
XRCC4 SLC4A7 â—¼   KO_DOWN_REGULATES ✅ - -1.45 1.44 PKG 28854368
TDG FADS2 â—¼   KO_UP_REGULATES ✅ + 1.44 1.44 PKG 28854368
PAXX SPP1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368
TDG SLC20A1 â—¼   KO_UP_REGULATES ✅ + 1.45 1.45 PKG 28854368
XRCC4 CFDP1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368
XRCC4 SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.51 1.5 PKG 28854368
XRCC4 LIG4 â—¼   KO_DOWN_REGULATES ✅ - -1.52 1.51 PKG 28854368
XRCC4 CCDC28A â—¼   KO_DOWN_REGULATES ✅ - -1.55 1.54 PKG 28854368
NHEJ1 FGF2 â—¼   KO_UP_REGULATES ✅ + 1.54 1.54 PKG 28854368
NHEJ1 HMGCR â—¼   KO_UP_REGULATES ✅ + 1.54 1.54 PKG 28854368
POLM CDC6 â—¼   KO_DOWN_REGULATES ✅ - -1.56 1.55 PKG 28854368
NHEJ1 MACROD1 â—¼   KO_DOWN_REGULATES ✅ - -1.59 1.58 PKG 28854368
XRCC4 PDCD4 â—¼   KO_DOWN_REGULATES ✅ - -1.6 1.59 PKG 28854368
NHEJ1 SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.62 1.61 PKG 28854368
XRCC4 FBXO28 â—¼   KO_UP_REGULATES ✅ + 1.65 1.65 PKG 28854368
TDG CDC6 â—¼   KO_UP_REGULATES ✅ + 1.65 1.65 PKG 28854368
NHEJ1 CDC6 â—¼   KO_UP_REGULATES ✅ + 1.68 1.68 PKG 28854368
XRCC4 LHPP â—¼   KO_DOWN_REGULATES ✅ - -1.7 1.69 PKG 28854368
TDG SPP1 â—¼   KO_UP_REGULATES ✅ + 1.74 1.74 PKG 28854368
NHEJ1 VIM â—¼   KO_UP_REGULATES ✅ + 1.75 1.75 PKG 28854368
XRCC4 UBL5 â—¼   KO_UP_REGULATES ✅ + 1.78 1.78 PKG 28854368
PAXX HMOX1 â—¼   KO_DOWN_REGULATES ✅ - -1.84 1.83 PKG 28854368
NHEJ1 HMOX1 â—¼   KO_UP_REGULATES ✅ + 1.85 1.85 PKG 28854368
XRCC4 MACROD1 â—¼   KO_DOWN_REGULATES ✅ - -1.86 1.85 PKG 28854368
NBN SPP1 â—¼   KO_UP_REGULATES ✅ + 1.86 1.86 PKG 28854368
XRCC4 KIF18B â—¼   KO_UP_REGULATES ✅ + 1.95 1.95 PKG 28854368
XRCC4 FGF2 â—¼   KO_UP_REGULATES ✅ + 1.99 1.99 PKG 28854368
XRCC4 MCL1 â—¼   KO_UP_REGULATES ✅ + 2.01 2.01 PKG 28854368
NHEJ1 SLC25A29 â—¼   KO_UP_REGULATES ✅ + 2.17 2.17 PKG 28854368
NHEJ1 SPP1 â—¼   KO_UP_REGULATES ✅ + 2.25 2.25 PKG 28854368
PAXX SLC16A3 â—¼   KO_UP_REGULATES ✅ + 2.28 2.28 PKG 28854368
NHEJ1 H1F0 â—¼   KO_DOWN_REGULATES ✅ - -2.34 2.33 PKG 28854368
NHEJ1 RBM3 â—¼   KO_UP_REGULATES ✅ + 2.35 2.35 PKG 28854368
TDG VIM â—¼   KO_UP_REGULATES ✅ + 2.48 2.48 PKG 28854368
XRCC4 CDC6 â—¼   KO_UP_REGULATES ✅ + 2.56 2.56 PKG 28854368
PAXX NDUFA4 â—¼   KO_DOWN_REGULATES ✅ - -2.58 2.57 PKG 28854368
XRCC4 DDX43 â—¼   KO_DOWN_REGULATES ✅ - -3.12 3.11 PKG 28854368
NHEJ1 CRAT â—¼   KO_DOWN_REGULATES ✅ - -3.19 3.18 PKG 28854368
XRCC4 SPP1 â—¼   KO_UP_REGULATES ✅ + 3.34 3.34 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368