Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
XRCC4 PNKP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15385968 5217205
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
NHEJ1 XRCC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
XRCC6 DNLI4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22990118 15520013 10757784 26496610
APLF XRCC4 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
XRCC4 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9430729 15194694 22939629 9259561 15520013
PNKP DNLI4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15385968 17353931
PRKDC XRCC4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PRKDC DNLI4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22529269 10608806 15194694
DCR1C DNLI4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23219551 22529269
APLF DNLI4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 17396150 26186194 23178593 28514442
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
XRCC4 DNLI4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 11702069 15520013 22658747 10757784 9705934 10854421 11809878 21070942 32296183 31548606 23219551 17567543 28514442 25416956 30496552 22529269 15194694 25910212 9259561 26186194
DCR1C PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11955432 33961781 22529269 15936993 15456891 31900314 16857680
NHEJ1 DNLI4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 22658747 17567543 16439205
XRCC6 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8422676 20711232 19303849 26175416 28345663 30585729 17308091 22939629 26496610 10750018 15941674 33005030 21969602 15520013 10064605 21575865 26446488
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
APLF XRCC6 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
XRCC4 APLF â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
XRCC4 APLF â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
XRCC4 PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 21637298 26186194 17353931 12032095 32296183 15385968
PRKDC NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC6 NHEJ1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PRKDC PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23433795 21824916 24000320
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368