Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RECQL4 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19567405
RAC3 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17625931
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
DIAPH1 RHOB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15944396 17198702
ELK1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17505916 23818898
ELK1 UBE2I â—¼   SUMOYLATION ✅ 2.0 0.8 intact 17036045 5219211
MAP2K1 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10716983 10997882
FBXW7 SHPRH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NBN UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
WRN RAD52 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216387 12750383
WRN RAD52 â—¼   COLOCALIZATION 2.0 0.8 intact 5216387 12750383
S100A16 S100A14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LAD1 PKP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
WRN CDA â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
ATM WRN â—¼   PHOSPHORYLATION 0.8 0.8 Signor 10608806
RAD52 PRSS8 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
EPCAM PKP3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EPCAM LAD1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB CD44 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
CD81 RHOB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
RHOB DLG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB DSG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
ICAM1 PAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB SCRIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
NBN TERF2IP â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
HPCA SLC16A3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
XRCC4 FAM9B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25416956 32296183
ATM NBN â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10802669
NBN SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
RAD18 PAK1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
NHEJ1 TDG â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
XPA ERCC6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20541997 8999876
RAD52 WRN â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FANCM RAD52 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
RAD18 CD81 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
ERCC6 ERCC5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8652557 16916636 16713569 16246722
PAK1 SCRIB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 31980649
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
SLC16A3 BSG â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10921872 11719518 16260747
SLC16A8 BSG â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10921872 11719518 16260747
CD44 ICAM1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 22566907 23620508 23886063
SHPRH RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 17130289 17108083
SLC16A3 SLC16A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10921872 11719518 16260747
SLC16A8 SLC16A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10921872 11719518 16260747
SLC16A3 SLC16A8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10921872 11719518 16260747
SLC16A3 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
RAD52 SLC16A3 â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
ATM NBN â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
PAK1 RAC3 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
ICAM1 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
S100A14 S100A16 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
RHOJ PAK1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 31871319 32814053 10967094 28514442 14521508
DCLRE1A SLC16A3 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
ERCC5 TDG â—¼   KO_DOWN_REGULATES ✅ - -0.96 0.95 PKG 28854368
SHPRH SLC16A3 â—¼   KO_UP_REGULATES ✅ + 0.96 0.96 PKG 28854368
ERCC6 SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
XRCC4 ICAM1 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
WRN POLB â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
WRN POLB â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
AHR PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18001219 12548657 15213229 19056653
WRN ATM â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
WRN ATM â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
ATM NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 12433983 12861053 17485521 23146902 10839545 19413330 15302935 27602502 17429352 19523210 24360018 20068231 17507690 17570479 10608806 12598907 18669648 25088203 18003706 11252893 17431132 23097684 10766245 12814430 10802669 21664921 26512707 10839544 11927276 21130714 17525332 12447395 14707289 15733840 15279770 25119968 18644472 28822740
ATM DCLRE1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15456891 18848520
ATM FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17525332 26774286
XPA DDB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11278856 23038248 18614043 25154395 14517266 19056823 20368362
RHOD DIAPH1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11784792 28486133 22665057 31871319 17916560
RHOA DIAPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22820501 12773565 18218625 16109481 15864301
ERCC6 ERCC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16916636 8652557 16713569 16246722
PAK1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 18593598 27542844 21371233 22105362 22981863 18668521 27169363 12876277 31416844 23331499 33789117 7873542 29551131 28225038 19595712 11435472 9351825 25794709 9416003 21248166 14993270 23701950 18940914 16129686 11948406 23162738
PEBP1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10757792 10490027
RAC2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9705280 23331499 10224076
WRN RAD52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 12750383 12919958 17118963
UBE2I TDG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15823533 18691969 21284855 15959518 11889051
UBE2I TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18512959 24753249 18691969
NHEJ1 CD81 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
ERCC6 CDA â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
POLB SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
TDG SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
XRCC4 CDA â—¼   KO_DOWN_REGULATES ✅ - -1.23 1.22 PKG 28854368
RECQL4 SLC16A3 â—¼   KO_UP_REGULATES ✅ + 1.22 1.22 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
FANCM SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.25 1.24 PKG 28854368
XRCC4 TDG â—¼   KO_UP_REGULATES ✅ + 1.27 1.27 PKG 28854368
ERCC5 SLC16A3 â—¼   KO_UP_REGULATES ✅ + 1.29 1.29 PKG 28854368
RAD18 SLC16A3 â—¼   KO_UP_REGULATES ✅ + 1.31 1.31 PKG 28854368
PAXX ICAM1 â—¼   KO_UP_REGULATES ✅ + 1.37 1.37 PKG 28854368
WRN SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.4 1.39 PKG 28854368
XRCC4 SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.51 1.5 PKG 28854368
XPA ICAM1 â—¼   KO_UP_REGULATES ✅ + 1.51 1.51 PKG 28854368
NHEJ1 SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.62 1.61 PKG 28854368
ERCC5 ERCC5 â—¼   KO_DOWN_REGULATES ✅ - -1.7 1.69 PKG 28854368
ATM SLC16A3 â—¼   KO_UP_REGULATES ✅ + 1.73 1.73 PKG 28854368
RAD18 ICAM1 â—¼   KO_UP_REGULATES ✅ + 2.21 2.21 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
PAXX SLC16A3 â—¼   KO_UP_REGULATES ✅ + 2.28 2.28 PKG 28854368
DDB2 SLC16A3 â—¼   KO_UP_REGULATES ✅ + 2.32 2.32 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
XPA SLC16A3 â—¼   KO_UP_REGULATES ✅ + 2.73 2.73 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
PAXX PAXX â—¼   KO_DOWN_REGULATES ✅ - -3.91 3.9 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368