Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UBE2I SATB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ZHX1 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZHX1 CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
B2M HSPB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 26465331 0133994
KCNIP3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PARK7 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ELK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TBP APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RANBP9 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR4A2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMC3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HMGB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AR APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16987234
SMAD4 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12099698 15242331
AR PPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18212046 20610535
AR CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24810056 20610535
AR PIM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 13679438 20610535
AR MEF2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23598283 20610535
AR RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12069693 20610535
AR TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21303954 20610535
AR VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15805579 16425262
AR RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24119295 20610535
TDG AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129768
AR SCNN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17721441
NR3C1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17016446
ATF2 NR4A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12114266
CHUK AURKA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17939994 0706493104
IKBKG AURKA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17939994 0706493104
AURKA CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
AURKA HNRNPD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
CHFR AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15793587 17442268
CHD3 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VDR BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23220548
NR1H3 BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19032342
FANCM BHLHE40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20347428
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
JUN BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16229810 17434164
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
PPARA CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRIM24 CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1101544108 21531907
SOX6 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26893351
HIF1A CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18461556 18381421
HDAC1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16431920
JUN CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17965828 20506344
STAT1 CEBPE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16918696
RARA CEBPE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14576045 12032776
CETN2 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23751493 26151477
KPNB1 CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
TCERG1 CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
NPM1 CHD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CSNK2B TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11997511
SUMO2 CTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20176810 20098713
NCOR2 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16287852 23331499
UBE2I DACH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD4 DACH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14525983
XPO1 DHX9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
DHX9 DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
JUN DHX9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22550165 18180292
DNM1 MX1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TRIM27 DNMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DNMT1 TRIM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
UBE2I DNMT3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18762900 11735126
TBP EDF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8164657 9710580
EGR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2115122 1427072
ELK1 UBE2I â—¼   SUMOYLATION ✅ 2.0 0.8 intact 17036045 5219211
MAP2K1 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10716983 10997882
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
TP73 EP300 â—¼   ACETYLATION ✅ 2.0 0.8 intact 11804596 5215037
SKI EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17469184 10575014
EP300 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 20089040
EP300 MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12371907 11796223
THRA ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11578528 11687272
FOXM1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346 17875680
ESR1 TSC22D3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23183181 15336700
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
ESR1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 18511507
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
ESR1 TRPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23031797 18414489
ESR1 JUNB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11477071
FOXM1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346
FOS FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10903433
TP73 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19788416
TP63 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15944736
STAT1 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17992189
FMR1 PSME3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
RARA FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19546303 9507016
PPARA FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17360982 18754816
MITF FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14737107
HSF1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9341107 11026560
FOS SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11854297
FOS NFATC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15073183 23619911
FOXM1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16965535
UBE2I FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16055711 16236267
FOXL2 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
FOXL2 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19010791
FOXL2 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
FOXL2 NR5A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17360647
HABP4 NPM1 â—¼   COLOCALIZATION 2.0 0.8 intact 7041060 19523114
NPM1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219698 17318229
TRIM24 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1101544108 21531907
SMAD4 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
HSF1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19793920
HIF1A HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19071119 6802010
HDAC5 MEF2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10748098 15194749
HDAC5 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10737771 11062529
HDAC7 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22172637 20693714
HERC2 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
MITF HERC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22234890
THRB HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16862226 18239067
HIF1A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15794924 19828020
HIF1A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15699159
STAT1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19646959
SIAH1 HIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SIRT1 HSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23349863 19229036
HSF1 UBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20692357
HSF2 TRIM54 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
HSF2 MAP2K4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11557063
PCGF2 HSF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18211895
UBE2I IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14651848 16906147
XPO1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TBP JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17074809 21106530
JUN SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
JUN PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1325459 19651778
JUN MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9733728 20353950
JUN PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16729332 20143420
JUN VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15930183 17121851
JUN TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910340 9448005
MEF2C JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9384584
JUNB MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15558021 15666830
KCNA5 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0606702104 17261810
NR3C1 KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27777311
SREBF1 KPNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10397761 31875875
KPNB1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
LMNA NUP153 â—¼   COLOCALIZATION 2.0 0.8 intact 20561986 7893748
MAP2K4 MAP3K5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12189133 8974401
NCOR2 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17456789 20137375
NCOR2 NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9556573 10612426
NFATC1 TRAF6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17092936 17239241
PIM1 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28235034 11823475
ZCCHC7 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SRSF1 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218180 16376875
NPM1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6541703 18259216
NPM1 SUZ12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NRIP1 NR1H3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11790787 17684114
NR1H3 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17054913 22279938
NR1H3 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23633563 12697904
TCERG1 NR1I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NR3C1 TRIM63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18615595 18612045
NR4A2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15591535
TBP NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 9649342
TDG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129768
NR3C1 NR4A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15591535
NR5A2 UBE2I â—¼   SUMOYLATION ✅ 2.0 0.8 intact 17036045 5219211
NRIP1 RORA â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NUP153 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12917407 23331499
STAT1 PIM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10068671
PPARA RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAT1 PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24242046
PPARA PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17275789 22033933
PSMC3 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53BP1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAN TRIM23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19041634
TP73 RNF144B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0911828107 20615966
TRPS1 RNF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12885770 5216574
RNF4 TRPS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12885770
SIRT1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16998810
TDG SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ZMYM2 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SOX10 SOX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17084361
UBE2N SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO2 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
UBB TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TBP TAF12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219590 17268553
TBP TAF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20189987 15637059
THRA THRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1782215 17761769
XPO1 TOP2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
UBE2I TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
TP53BP1 UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRIM23 TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
UBE2I TRIM54 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
UBE2I TRPS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17391059 23772552
UBE2N UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RAN UBE2I â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
GMEB1 GMEB2 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
RAD18 SEMA6A â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
EP300 CHD4 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 32699137 30110629 15189737 26546801
CHMP1A CHMP5 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
JUNB EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21937452 15308641 17510411
TAB2 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
TRIM23 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
RAD18 TP53BP1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
EP300 ATF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24069158 10327051
ATF2 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 AURKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 21761334
AURKA DHX9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 23443559
CBX5 AURKB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20562864 20231385
DNMT1 CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12867029 17470536
CBX5 SUZ12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 20562864
CCDC6 PCBP3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
JUN CHD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 21196933
ESR1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
CTBP1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15834423 21102443 16122695 35016035
ESR1 CTBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 DHX9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 19805454 21182205 20348541
ESR1 DRG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
NR1H3 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33742100 25962847
FOS ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
ESR1 SUZ12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ESR1 FAS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
ESR1 KAT2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
FMR1 HABP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21771594 28695742
SUZ12 GTF2I â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24457600 17970752
JUN HDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 17056544
HDAC7 HIF1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15280364 21148070
HERC2 LMNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29426014 25476789
ILKAP SMAD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
JUNB RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RARA KLF5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16224062 18466769 21383775 16102021 12101409
SUMO2 MEF2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19684601 21693764
MEF2A MEF2C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 33961781
NR1I2 NCOR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16144941 12072427 16219912
TBP PSME3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32296183
TOP1 RBM25 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
HIST1H4A UBB â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
CHD4 HIST1H4A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
RNF4 UBE2N â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
SUMO2 ZHX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19471022 21252943 16524884 21693764
BRCA1 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25184681 29656893 23901102
CTBP1 CHD4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 31041561 24981860
CTBP1 TRPS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 35016035 26186194 28514442 31041561
DHX9 TOP2A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15034300 12711669
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
TAF10 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 7923369
ESR1 JUNB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 11477071
TRAF3 ETV6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22792062 35140242
SUMO2 ETV6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12626745 19471022 35140242 21693764
MAFB FOS â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
FOS MITF â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 9918847
HIST1H4A TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
SMAD4 JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649 10220381
JUN TOP2A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649 8387155
PSME3 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
UBE2I SMAD4 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5217094 15231748
BRCA1 RBBP8 â—¼   UBIQUITINATION ✅ + 0.83 0.83 Signor 16818604
RBBP8 BRCA1 â—¼   RELOCALIZATION ✅ + 0.83 0.83 Signor 24832651
CBX5 DNMT3B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
SH3KBP1 UBB â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HDAC5 MEF2A â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
BRCA1 UBE2N â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CHD4 CHD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24981860 28977666 22939629 32744500 9885572
EP300 RAN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33742100 12649209
HIC1 SIRT1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
STAT1 HSF1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9880553 16189514
TOP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
NUP153 RAN â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
SUMO2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21147198 20016594 20016603 22689573 21693764
BRCA1 TOP2A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25184681 15965487
CCDC6 HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20498639 22863883
UIMC1 CDK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19615732 23264621
SUMO2 CHD3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19471022 32786267 15383276 21252943 21900206 16169070 16713569 24018422
MEF2C EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21556048 9001254
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
EP300 KLF5 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
ESR1 GRIP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17545996 9773983 17932106
HIF1A JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25879517 19738058 11739718
TRAF6 IRF7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30927622 22095711 21743479 26224488 18710948 21183682 15361868
TAF1 JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11316804 16713569
TBP RNF4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11696545 9710597
SUMO2 SOX6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 35140242 16442531
RAD18 TRIM27 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
SUMO2 ZMYM2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MAP2K4 MAP3K5 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
NR5A1 PPARGC1A â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
AR SPOP â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
NRIP1 THRA â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
UBB UIMC1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
AURKA BRCA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22110403 26831064 14990569
DHX9 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11823437 25609649
EDF1 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 31527615
SRF ELK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8083237 9010223 35016035 10606656
SMAD4 EP300 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18215124 25514493 10887155 22033265 9679056 14612423 9843571
NCOR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9171229 20392877 12738788 14715875 23403292 9702189
ESR1 RARA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25604459 25303530 9717844
ESR1 STAT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 25303530
TAF1 FOS â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16713569 8065335
HDAC1 PTMA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16189514 12634383 16713569
HDAC1 NR3C1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
TBP HMGB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9880542 8006019 16713569
TBP HSF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11005381 16713569
NCOR2 KLF5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18500350 35140242
UBB RAD18 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28506460 24981860
SUMO2 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19471022 25027693 19394292 18381449 32786267 21252943 20797634 21693764
ATF2 JUNB â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
BAG3 PRKAR1B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
ASF1B HIST1H4A â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
LMNA SREBF1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
BCL11A HDAC1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
ESR1 PTGES3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
BAG3 HSPB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
BAG3 HSF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25036637 27173435 23824909
CBX5 CHD4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 28977666 32744500 15882967 27705803
CTBP2 HIC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20547755 16762039 19486893
DACH1 JUN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16980615 17182846 25609649
ESR1 UIMC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31527615 17311814
ESR1 TRPS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23403292 31527615 26153859
NCOR2 FOS â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20195357 10777532
SUZ12 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26344197 22439931 24457600
ZMYM2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26496610 23752268 28514442 18806873
NCOR2 VDR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9878542 12460926
TDG RARA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12874288 24394593
HDAC7 MEF2A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HSF1 HSF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EP300 STAT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
SMAD4 TRIM33 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EP300 TP73 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ESR1 TRIM24 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CHD3 CHD4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CTBP1 NRIP1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DNMT1 DNMT3B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TRIM24 TRIM33 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SRSF1 TOP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SATB1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16630892 12374985 16189514 15713622
CTBP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11751867 10196224 16713569 21102443 31636387
BRCA1 UBA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12438698 26831064 11278247 15184379 12485996 11927591 12887909 14638690
HDAC1 CHD4 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 26949739
NRIP1 CTBP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15060175 16189514 16713569
EDF1 NR1H3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12040021 16189514
EP300 VDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32603375 15647825 21988832 20089040
EP300 PPARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18797151 9407140 10336495
EP300 RORA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 9862959
SMAD4 JUNB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10220381 16189514 15231748
NRIP1 PPARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9626662 10022764 16189514
TBL1X SIAH1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 11389839
TOP1 SRSF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12270705 9611241 15848144 20805487
TAF10 TAF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17643375 14580349 23292512 7923369 29111974
TCEA1 TBP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20562857 10454562 9305922
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTBP1 CTBP2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
IRF7 TRAF6 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ESR1 NRIP1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
NRIP1 RARA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
JUNB ATF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 16511568 20102225
STAT1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10792030 16713569
HDAC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 21102443 16713569
HABP4 CHD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16455055 16169070 12505151
HDAC1 CHD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28977666 22939629 26496610 9804427 23752268 20585571 11784859 17827154 28514442 27068747 9885572
CTBP2 CTBP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 27107012 33961781 26344197 26496610 35016035 31041561 30585266 26186194 24722188 21988832 16713569 9858600 25416956 28947780 16189514
SOX6 CTBP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 35140242 16713569 11504872
EP300 PTMA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11967287 16713569 10891508
TBP ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11595744 31527615 16713569 9259327
TDG ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12874288 16282588
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
GTF2I SRF â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12082086 9334314 9584171
HDAC1 TOP2A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11062478 11136718
TBP JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7685215 7848298 16055710 16713569
PSMC3 UBB â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
NCOR2 RARA â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
AR NCOR2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ATF2 FOS â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC7 NCOR2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
NCOR2 THRB â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
FOS JUNB â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
SUMO2 SATB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 24782567 20351170 18408014
UBE2I ZHX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21988832 23686912
FAS CASP8AP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10235259
UBE2I CASP8AP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21338522 19615980 23673342
STAT1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19508864 9841227
TBP APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8015372
AR NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21273442 20610535 23689136
AR SNAI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 16541421
AR TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 9238003
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
SMAD4 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12226080 16713569
TRIM24 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9115274 19909775 16713569
FOS ATF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 1828107 32296183 25416956 16511568 23661758 25609649 20102225 26186194 20195357 1827203
ATF2 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23443926 19491401 15767263
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
AURKA CETN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21731694
NR1I2 AURKB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
HIF1A BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020
JUNB BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 18259752 16713569 28514442 25184681 12080089
DHX9 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12592385 9662397 26831064 16713569
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
JUN BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25609649 12080089 16713569
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DNMT1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19943104 22197621 20631324
BRCA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17873885 11320250 14636569
CDK1 FOXM1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 18285455 19160488 15024056
CEBPD CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10373535 7910803 10623469
NR3C1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27777311 11279134
TSC22D1 CHD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CTBP1 CHD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SUMO2 CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSNK2B DNMT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBE2I CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20176810 20098713 12679040
CTNNA1 CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
DNMT1 DNMT3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24423239 16481298 20155458
DNMT3B TSC22D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SOX10 EGR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22492709 19922439 12538520
SOX10 EGR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16582099 16311519
ELK1 TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17074809 23454483 17499043
EP300 TFAP2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12586840 11694877 11744733
EP300 KAT2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23667505 23555303 21559432
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11796223 11062529 9001254
NRIP1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9115274 26153859 8887632 16439465 26166704 9192902 21182203 23403292 33731348 7641693
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
NCOR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17591692 23015261 15802375
ESR1 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664452 17556531 12710998
TDG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12874288 17129768
TFAP2A FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11310795 7528667
NR3C1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15802531 15590983 15289452
FAS MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25241761 11495919
TBP FOS â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7685215 16713569 8065335 16055710
UBE2I FOXL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20209145 19744555
FOXL2 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19010791
FOXM1 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15358835 7532283 8817653
HIF1A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24015760 16511565 21148070 11641274 17273746
STAT1 HDAC7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
UBE2N HERC5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16112642 16428300 16122702
MITF HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15983061 22012259
HIF1A RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15270719 14742449
HSF2 HSF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25036637 26496610 26186194 26727490 28514442 12813038
TP63 HSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
TAB2 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21988832 23986494 17626013
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
JUN NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 7823959 8733011
NR1I2 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
MEF2C PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18946175 12181572 19553684
MITF PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23416000 23477830
MITF SNAI2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12444107 1999537
RARA NCOR2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11929748 16219912 19377461 9256429 7566127 17475621 9380707 15604093 20543827 16713569 10082574 9415406 25303530
SIRT1 NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22395773 15175761
PPARA NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18758514 12595494 18498712
NRIP1 NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10022764 16189514 15604093
NR1I2 SCNN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
TP63 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
TFAP2A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9015328 7794935
SUMO2 NR5A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15192092 15192080 21467194
UBE2I NR5A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15192092 15192080 21467194
NR5A1 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23471216 23340581 23537609
RARA NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21310893
UBE2I PARK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11477070 15976810 18339323
PDPK1 TAB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17496917 15125833 16056267
TP63 PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19458633
PPARA SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12730331 1273033 21540177
PPARGC1A PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21775429 10669761
UBE2N RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
THRA RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
RARA THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
SMAD4 SKI â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 14699069 15231748 25670202 15761153 20959473 31932471 28468752 12764135 26977879 12732634 10531062 17469184 12857746 19032343 12419246 25609649 12874272 14525983
XPO1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11074002 23331499
SNAI2 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18485278 20138990 19502595
TAF12 TAF10 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 14580349 24981860 19114550 7729427 12601814 23292512 9603525
TBP TAF10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16945932 18722179 12020826
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
UBA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17597759 24816145 21209336
DACH1 PRKAR1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
EP300 MEF2A â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
NUP107 NUP153 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
RAD18 NACC1 â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
UBE2N UBA1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 27173435 14517261 29537486 18678647 30097011 27182664 25527291 33619271 31638574
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
TOP1 TOP2A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
UBA1 UBE2N â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
MEF2C HDAC7 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 11279209 23752268 18463162
MEF2A HDAC7 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 20590529 22308472 16980305 16956611
TAB2 TRAF6 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RNF4 SUMO2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
UBA1 UBB â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
FANCM AURKB â—¼   KO_UP_REGULATES ✅ + 0.92 0.92 PKG 28854368
RAD18 DNMT3B â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
KAT2A TAF10 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
ATXN7 TAF12 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
JUNB FOS â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218398 16511568
GMEB2 GMEB1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 33961781 28514442 10523663 10894151
DNMT1 UBB â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
RAD18 UBB â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CHD3 HDAC1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
RBM25 SART1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
PPARA PPARGC1A â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ATXN7 KAT2A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
JUN JUNB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 25609649 28514442 33961781
TAF10 KAT2A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 17643375 24981860 19114550 12601814 17375202 31753913 10373431
NR5A2 PPARGC1A â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 HDAC1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
IKBKG TRAF6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
SUMO2 TDG â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
UBE2N UBE2NL â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
UBB UBE2N â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
HIC1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 17213307 12052894 19486893 16762039
RARA NRIP1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12503607 16189514 8887632 12549917 14581481 17641689 16713569 25416956 10082574 10531331
TAF5 TAF1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 9045704 14580349 26344197 22939629 31753913 7680771 29111974
NCOR2 TBL1X â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
SUMO2 UIMC1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
KPNB1 NUP153 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
TAF5 TBP â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
HDAC1 DNMT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22274925 10888886 15870198 21670149 17707923 10615135 26794444 17967891 20613874 12473678 17934516 23708667 27593931
HIF1A EP300 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 18268343 15154850 12914934 19074848 25192544 22789427 20829524 21148070 17502379 26826385 22075993 16543236 19680224 20603618 19589782 11063749 23618863 26135796 27808477 22219185 15155277 11823643 17906695 19666581 21187066 16189267 8917528 23746844 19940151 19071119 26944191 15261140 24421387 20000859 12778114 14691445 12042299 22684029 12588875 17382325 23966271 15342390 22735262 27320910 26751287 24821806 23448368 11959990 15280364 11940656 19696166 20620956 16081065 22908229 18047470 16847340 22807441 23880760
XPO1 RAN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 20026644 26344197 10779340 22939629 27613868 10944119 12070164 9323133 21909257 32585100
TBP TCEA1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ATXN7 TAF10 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
NCOR2 PPARA â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RAD18 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
BRCA1 RBBP8 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TRAF6 UBE2N â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SKI SMAD4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TAF12 TBP â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
KPNB1 RAN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAN XPO1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
TAF10 TAF5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF1 TAF5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF10 TAF12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF12 TAF5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF1 TBP â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TAF1 TAF12 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TAF1 TAF10 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TAF10 TBP â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
DYRK2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20831597 22307329
CDK1 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 14657031 15279786 15917306
JUN APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8063812 11677255 8015372
TFAP2A APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17651731 9048735
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
NCOR2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19223455 16373395 21720703 22508987
AR TRPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535 15613454
AR THRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19460858 20610535
AR SCNN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16172422 20610535 17721441
NR2C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 16713569 12949936
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
RAN AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10400640 16713569 18565325
HIPK3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9725910
BRCA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11085509 16713569 11016951
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
NRIP1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9368054 16527872
CDK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 26573794 12569365 22275373 25704883 17043241 23321516 9725910 24480624 21799006 24424504 28062857 21820033 25950519 28415597 27450452 25691442 21782001
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
NCOR2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 23331499 11923464 15062576 14593076 17356171 22508987 12441355 12771131 20812024
AR JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11577103 11518798 9211894 8798722 16713569 9591784 17721441
AR NR5A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 11518799
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AR PARK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12612053 17510388
ATF2 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11042264 12453892 15907483 9712902 17314398
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
SMAD4 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085140
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
BRCA1 AURKA â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
BRCA1 AURKA â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11877377 15459660 19075565 19793801 20011137 20029420 21060331 21337561
HIF1A AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18562694 19828020
AURKA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22864622 22340593 18026198 24775809 14990569
FOXM1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15817462 15689977 17173139 16314512
AURKB TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28415769
AURKB HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22865920
HSF1 BAG3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23983126 19006120 20692357
BRCA1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
CTBP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20818429 21681822 23303449
BRCA1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20160719 18851829 9000507 21407215
UIMC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17525341 17525342 17525340 17621610
CDK1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9244350 21706030 10550055 17570479 19683496 16713569 26745677 32193285 26719576
BRCA1 RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 21908405 18285836 16713569 15485915 25310973 9738006 17525342 17525340 16843262 24085845 25184681 26387952 18369654 9811458 16818604 20351172 23416467 19442256 10196224 10910365 19452558 11739404 25252691 10764811 25659039 17965729 11689934
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
LMNA CDK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22986494 2188731 2344612 2188730
CDK1 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14551205 15279786 17243194 17303408 17660363 18414028 18590585 7575488
CDK1 GOLGA2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 15678101 7737117 11238451 11306556 18167358 1902553 9150144 10679020 9753325 11285137
TP63 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11593387 19861536
TP73 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19861536 11593387 19067706
CDK1 LMNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 19007248 16565220 20166139 17081983 18767875 20393185 23870088 17137347 19413330 18187866 19194518 30190500 19664995 19415658 15302935 7925482 16083285 95010153 24741066 20068231 18452278 18077418 17570479 18491316 18669648 32071079 23427156 2344612 18691976 26922519 17287340 18815303 20068230 19651622 20058876 19691289 17924679 22367880 19165338 19664994 18707149 21389115 16964243 18212344 24556839
CDK1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15985436 17620410 12676926
CDK1 SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16880739
CDK1 GOLGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 19007248 19691289 18691976 9753325 20068231 10769027 16964243 18669648
CDK1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 7575488 18590585 17243194 17303408 21524151 17570479 25607646 29603287 20126263 17660363 30685087 15279786
CDK1 CSNK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 16335537 1939094 19007248 17081983 25788269 18691976 20230923 20068231 19387552 17570479 12551973 12396231 19581576 7578274 18669648
CDK1 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19107194 17570479 24011073 28756945
CDK1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21565170 27220480
CDK1 UBA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19651622 20068231 7724583 19413330 7673335 18669648 9099746
CDK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 17081983 12058066 27253419 22285574 25908633 20333249 16912078 27553022 19933706 16083285 20068231 27619510 17570479 18669648 7213797 81161106 26536659 11278991 17287340 17924679 15190079 14670079
CDK1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25971971 8114697 11684694 17570479 12609978
CDK1 FOXM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23240008 19737929 28387346 19160488 15024056
TFAP2A CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19089912 11688971 11050170 10588870
CEBPA PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10854692 9867832 8093246 7935427 10681569 10224054 17094771 12560325 12237288
NR3C1 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10649448 1840554
EGR2 CHD4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 16136673 16574654 15836632 18456662 8918830 10656257
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
TRAF6 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15836773
TAB2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14960582 15836773 11274345 20194509 18855897
CHUK NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 18374649 16846590 23041317 23343355 16382138 15494311
CTBP1 NRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 24722188 11509661 18374649 17085477 16713569 15060175
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281
SUZ12 DNMT3B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
EGR2 SOX10 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16136673 25974668 11734543 8842374
STAT1 EP300 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10918613 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15265520 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11804596 19407812 15175157 19788416 12660246 19218448 10648616 15454570 16998810 25675294 15893728 18663001
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11864601
EP300 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9660747
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
NR5A2 ESR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 PTMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10938099 12149645 11459795
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8300756 8912864 8732679 11038749 15831516 15870697 10076999 9626663 18414489
ESR1 NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20200160 10379892 16391242 22071320 18414489
ESR1 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23911789 19376833 16091743
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
NRIP1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9192902 23331499 8887632 9115274 7641693 26166704 12554755 26153859 21182203 16439465
NCOR2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12738788 14715875 9171229 9702189 20392877
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 17641689 15831516 9717844 9841885
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ETV6 GOLGB1 â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 29025582 28028030 24854988 28751768 19345670 17268528 23168613 27795560 30559310 31066629 17764812 16761019 21705501
TP53BP1 EXO1 â—¼   REGULATES ✅ 21.0 1.0 ACSN 11042216 11438669 11877378 15496928 15549137 15655342 15867354 17243194 18001825 18048416 18171670 18212739 18756267 19217833 19270065 19490890 20019063 20021983 20064462 20646866 9748285
JUN FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733515 12963547 10903433 19670268
STAT1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11309387 19262492 16317104 14602726 22805310
TP73 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18343378 16741250 15805279 19615968
TFAP2A FMR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10612627 16886907 15930016
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
STAT1 FOS â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
SRF FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9315625 10742173 8864058 8986626 19581295 9690619 10777594 11846562 12242287 2104799 17938209 9111305 8007980 12760745 11862715 1902475 8423791 10642500 10330504 10961986 9032300 2511007 8164681 7854423 17182846 2200737 9271374 10369679 8413226 19173292 9349499 1630900 8262053 10319327 7910456 9545312 9571041 9734357 8764983 12231642 2493627 14693367 18557893 7588632
GTF2I FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9584171 12082086 11934902 16611241 10082538 19097122 11313464
JUNB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1380150 2116003 8934539 11698415 9813041
NR3C1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16850320 9804760 1314076 8036015 8890955 8733011
STAT1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8874187 7510676 8830676 12600988 7507205 8770944 17558387
SMAD4 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9732876 10942775
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
HIF1A FOXM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22831955 19097132
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
HDAC1 SNAI2 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 NCOR2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 NCOR2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 SNAI2 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 SNAI2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
NR3C1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15826950 16762839 18762022 18028994
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
HDAC5 MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10737771 10748098 11062529 12626519
HERC2 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
UBE2I HIC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 23417673 27935866 20547755 17283066
HIC1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19649206 16269335 19525223 21277938 20693263 17638871 22064865 23704280
HIC1 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17283066 16269335
HMGB1 TRAF6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 18070982 15247281 21220427 12140561 12138165 8837778 19592497 18347055
UBE2I HSF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11278381 16713569 18211895
TRAF6 IKBKG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18180283 18347055 21220427 16547522
TAB2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
IKBKG STAT1 â—¼   DOWN_REGULATES ✅ - 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
TRAF6 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17562858 17728323 17947236 14695475 18180283 15620648 15125833 12867425 11057907
TRAF3 IRF7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
STAT1 IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22951020 11877397 16628196 22252317 12768031 15767254 15664995
TRAF6 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22095711 18710948 21743479 30927622 15361868
PPARA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10542237 17360982 18754816 15838301
MEF2C JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9069290 9252389 10523670 11158308 7760790 10849446 12054430
MEF2A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12574153 10330170 20590529 9252389 8355696 12016267 19389706 7760790 1406636 10403485 12054430
NR3C1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20499359 8639160 2169353 9731701
UBE2I JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11877416 16713569 16055711 10788439 8733011
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
TAB2 KPNB1 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10089876 10391247 11274345 11796223 12620219 14660645 14741051 15036616 15082531 17593948 18235236 18264787 18855897 19136967 19608982 23070005 2550447 7650486 9973469
RAN KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10779340 8909533 11024021 9214382 20658144 8576188 26496610 9102465 9135132 10944119 10037787 9045717
NUP153 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 35044719 10749866
PDPK1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8131746 8394352 15175348 15466476 94178255 7731720 7624324 8157000 8039496 8621729
MAP3K5 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TAB2 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TAB2 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20060931 21614932 12738796 11274345 18855897
MAP3K5 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 12556535 18408005 18855897 19392652 9162092 17462996 8974401 18641653 23331499 23850759 12655147 21614932 15911620 12738796 21133840 15998799 21232017 17541429 16000309 24378531 15592525 11053428 26192618 12878192 11274345
PIM1 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 16532036 14500571 12697749 25749412 11154276 26912789 30205811 19749799
TRAF6 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18292600 9774977 10523862 10921914 17724081 15310755
SMAD4 MEF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 16189514 11160896
SOX10 MITF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10973953 10982026 15760336 10938265 16494873 19026785 10942418 16921166
UBE2I MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10673502 16713569 10694430 16029420
SOX10 MITF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10973953 10982026 10942418 10938265
SMAD4 NCOR2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
PPARA NCOR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19955185 11845213
PTGES3 NHP2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
PTGES3 NHP2 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20473778 20713526 2191300 21945180 22869732 23551398
SUMO2 NOP58 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 24782567 20797632 25114211 21647297 25218447 20797634
UBE2I NOP58 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20797632 25114211 21647297 12196509 19596686
NR1H3 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 18854425 19366697 16831124 19933273 24277692 18202130 20868688 16112614 26120082 15855229 12730331 24265317 21094755 22511764 19716432 21266776 11287605 11694526 18420801 22984430 18684130 24458133 21540177 21979752 19258656 15330762
NR1H3 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 24713062 21071413 16189514 14960721 8621574
NR3C1 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17095578 16100117 11557972 11333185 11069927 12560325 26652733
NR3C1 SCNN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10212217 11266509 10419459 11390395
NRIP1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10659697 12773562 11266503 9920921 16189514 10364267
NR3C2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NR3C1 NR3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NRIP1 NR5A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16189514 11459805 12782406
RARA NRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 12403842 17641689 8887632 25416956 14581481 16713569 12503607 10082574 12549917 10531331
NRIP1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 12403842 17641689 8887632 25416956 14581481 16713569 12503607 10082574 12549917 10531331
NRIP1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23331499 10022764 9626662 16189514 9774688
TBL1X PPARA â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 17007889 11330046 9171241 11226238 27071062 19289416 18288277 16503871 14980219 16476485 17306620 10529898
SIRT1 PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15205477 15744310 15989956 18687677 19590512 19960022
SIRT1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23142079 21633182 19553684
SIRT1 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15744310 20640476 24003218 19553684
RNF111 SKI â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18451154 17510063
SKI SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 17145710 12764135 25609649 12419246 20959473 10485843 15231748 23331499 21071413 12874272 12732634 25670202 14525983 12857746 15761153 12793438 17469184 19032343 14699069 10531062
SMAD4 SNAI2 â—¼   UP_REGULATES ✅ + 31.0 1.0 ACSN 11074002 11279127 11792802 12490555 12702545 12809600 14623871 15265520 16510505 16617148 16713975 16831886 17093497 17403902 17490644 17550342 17563753 17671186 18297062 18832382 19208835 19412634 20731704 21199805 21317430 21614932 21883379 22006115 22406545 22945800 9389648
TRIM33 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 15820681 19135894 21597466 24307592
UBE2I SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 21988832 31515488 16189514 15637079 16713569 12621041 29892012 15231748
TOP2A SUMO2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24782567 17183683 18381449 25114211
TRAF6 TAB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF6 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 17145710 15492226 19675569 15932500 18180283 16251197 10882101 18299187 11259596 1551980 24061540 21988832 19112497 22924441 11518704 11809792 15836773 14633987 14751757 25290089 12496252 12609980 12242293 24735611 14982987 15327770 17720800
TBP TAF1 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 7597030 17375202 7680771 9153318 9660973 17884155 18391197 16713569 15870300 29111974 15564746 8858156 31753913 8995708 9858607 9674425 17967894 19240132 9603525 9311784
TAF1 TBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16858867 11316804 9699517 15808844
UBE2I TDG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15823533 18691969 21284855 15959518 11889051
UBE2I TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18512959 24753249 18691969
TP53BP1 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
UBE2N TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 17349954 17652783 18196958 19203579 19258535 19793861 19793862 19841479 19851286 22771115
TP53BP1 UIMC1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
TP63 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16462763 22521434 17716971 19622632
UBE2N TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18710948 1551980 17327397 11057907 15147900 18981220 21113135 17709375 31074699 19549727 18617513 24610907 27791197 29432170 19465916 23885119 15327770 27173435 21872579 25548215
UBE2I UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19549727 17698038
UBE2N UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RAD18 UBE2N â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
TDG SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
FANCM SLC16A3 â—¼   KO_DOWN_REGULATES ✅ - -1.25 1.24 PKG 28854368
RAD18 SLC16A3 â—¼   KO_UP_REGULATES ✅ + 1.31 1.31 PKG 28854368
RAD18 CHMP5 â—¼   KO_UP_REGULATES ✅ + 1.31 1.31 PKG 28854368
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368