Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FANCM CENPX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20347428
ATXN1 TENT5B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ZHX1 TOLLIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZHX1 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZHX1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ZHX1 CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ZHX1 CSNK2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZHX1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PPARG COL10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20414969 16023420
MYC CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21925595 23722468
PPP2R5E PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
FXR1 TLE5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
TLE5 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BHLHE40 DELEC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23426649 19624270
HIF1A APH1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16645044
ARNT BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12354771
STAT1 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19646959
RORC ARNTL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24737872
NR1D2 ARNTL â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24577401
PPARG ARNTL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19041764
PPARGC1A ARNTL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17476214
RORB ARNTL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18454201
NR1D2 ARNTL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18662546
BHLHE40 ARNTL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12397359 15193144
ARNTL2 PER2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19605937 19168071
ARNTL2 BHLHE41 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16685415 15147242
CCNK ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RAD54L2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HIVEP1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
KRTAP8-1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TOLLIP ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
DAZAP2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RBPMS ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
UBE2I ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
KRTAP19-1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 NUMBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SETDB1 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MDM2 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17347673 5219751
CHD3 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BRD7 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FXR1 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
NR1H2 BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19032342
VDR BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23220548
NR1H3 BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19032342
BHLHE40 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27226296 19589260
TP53 BHLHE40 â—¼   COLOCALIZATION 2.0 0.8 intact 17347673 5219751
FANCM BHLHE40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20347428
BHLHE41 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15066123 17660447
STAT3 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12393476
TP53 BTRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19196987 0812256106
BTRC RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 9990853
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
TP73 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16526280 22842668
EZH2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132185 21697275
STAT3 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11279133
CCND1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11279133
RBPMS CCNK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CCNK DVL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 CCNK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11988847
TP53 CCNK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
VIM CHD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PER2 CLOCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16474406 10531061
RELA COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19022820
RUNX2 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11331591 16029574
COX5B FANCM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STAT1 COX5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
PER2 CRY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10790862 11165242
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CSNK2A1 HIF1A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17382325 5219810
CSNK2A1 RELA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5212888 10938077
CSNK2A1 CSNK2B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TP53 CSNK2A2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CSNK2A2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10938077
FXR1 CSNK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
TP53 CSNK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
VDR CYP3A4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11991950
PPARGC1A CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16891307 16488887
PPARG CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
NR1H2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12917410 9013544
RBPMS DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NOC4L DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MAGED1 DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TOLLIP DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR1 ENO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
STAT3 EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23991099
RELA EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20495570
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
PPARG FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20416398 15644454
TP73 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19788416
TP63 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15944736
TP53 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9841917
STAT1 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17992189
FXR1 FBLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 HIVEP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 MAGED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GATA4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19501129 17975667
GATA4 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18974883 24204964
PPP2R1B HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
PPARG HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21151932 16431920
PPP1CA HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17008050
HIF1A MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12606552 15385570
HIF1A IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17504662 15723200
STAT1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19646959
TCF3 ID1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22564737 17490644
PPARG IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19160541 15187132
IL10 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12773629
RORC IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10820242 11550795
TP63 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2196176 9032395
STAT1 IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10068671 12244150
UBE2I MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12393906 20972456
PPP1CB MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23277204
PPP1CC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23277204
PPP1CA MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23277204
MDM2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 23839035
TP53 MLH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15781865
NR1H3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10890879 12551904
MYC PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19602047 11509615
STAT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10637230
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
PPARG MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16838108 11477074
MYOD1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16527841 19553684
MYOD1 TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10835425 9448005
MYOD1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18094043
MYOD1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18513743 16007124
STAT3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 12947115
NFIL3 PER2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17274955 23496259
NOC4L VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PER2 NPAS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16474406 10531061
RORA NPAS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20817722
NPAS2 PER2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19106159
PPARG NR1H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1H2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1H3 PRKAA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19125418 20395595
NR1H3 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17054913 22279938
PPARG NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1H4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21279417 15973435
USF1 PCK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19720831 20461355
RELA PCK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20137375
RBPMS PHF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PIK3R1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25814554 15021914
PPARG RORC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9702045 19737866
PPARGC1A PRKAG3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21451146 19112161
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PPP1CA STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19440292
TP53 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
PPP2R5D PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
TP53 PRKAA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 PRKAG3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
RBPMS RAD54L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TOLLIP RBPMS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UBE2I RELA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25218447 22649547
RELA TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910340 8524315
RELA STAT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
RELA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
SETDB1 TOLLIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SETDB1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
SMARCB1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAT3 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19088723 14712222
TP53 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
UBE2I TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
VIM TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
VAC14 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TCF3 MYOD1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 1649701
BHLHE41 CLOCK â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
BYSL NOC4L â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
BHLHE40 TENT5B â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
BHLHE41 CRY1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
KRTAP19-1 PRR20C â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KRTAP19-1 PRR20D â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KRTAP19-1 PRR20E â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
BHLHE40 KRTAP6-2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KRTAP19-1 PRR20B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
KRTAP19-1 PRR20A â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
BRD7 SMARCB1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
BHLHE40 KRTAP8-1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
BHLHE40 KRTAP19-5 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
BRD7 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20215511
CLOCK NPAS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 23555304
PPARG RARA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 32929351
SMAP2 RBMS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29395067 27173435
KRTAP19-5 PRR20C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRTAP19-5 PRR20D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRTAP19-5 PRR20E â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRTAP19-5 PRR20A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRTAP19-5 PRR20B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
BHLHE41 PER2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ARNTL PPP1CA â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
EZH2 SIN3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27634302 24981860 27705803
FUS NONO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25192599 22939629 26344197
MYC NONO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 29467282 17314511 17967896
BHLHE40 KRTAP19-1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
BHLHE40 ROR2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
CSNK2A1 HDAC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RELA STAT3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BTRC HIVEP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MDM2 TP63 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MYC HIF1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15071503 28205554 28628118
HIF1A STAT3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ARNTL2 NPAS2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HDAC1 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
BHLHE40 RHOBTB3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
MYOD1 TCF3 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
FANCM CENPX â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24699063 26625197 20347428 22510687 20347429
PHF1 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
STAT3 HIF1A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18985005 23604114 15735682 23991099
RORA MYOD1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16713569 9862959
RXRA MYOD1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9692544 16713569
STAT3 STAT1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6730629 8662591
KRTAP8-1 VENTX â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
BHLHE40 SMYD1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
KRTAP6-1 KRTAP6-2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
IL2RA IL2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17032757 1993646 16477002
KRTAP19-5 KRTAP8-1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
PER2 MDM2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 30425162 34257372 25103245
NR1H4 PPARGC1A â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
RXRA FUS â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32814053 9440806 16713569
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
BTRC FBXW11 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HIF1A MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HIF1A VEGFA â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MYC PFDN5 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
KRTAP19-5 KRTAP6-2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
ARNTL2 CLOCK â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MYOD1 STAT3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 12947115
PRKAA1 PRKAG3 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ID1 MYOD1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
STAT1 STAT3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
KRTAP19-1 VENTX â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
BHLHE40 KRTAP1-3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
BHLHE40 BYSL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
HDAC1 CHD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28977666 22939629 26496610 9804427 23752268 20585571 11784859 17827154 28514442 27068747 9885572
MYC MLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29467282 12584560
PPP2R1B PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8392071 8286818
BHLHE40 PRR20C â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BHLHE40 PRR20D â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BHLHE40 PRR20E â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BHLHE40 PRR20B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BHLHE40 PRR20A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BYSL VIM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
NR1H4 RXRA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
PRR20C ROR2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PRR20D ROR2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PRR20E ROR2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PRR20A ROR2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PRR20B ROR2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRTAP6-2 VENTX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
UBE2I ZHX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21988832 23686912
CSNK2A1 ZHX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16169070 16713569
STAT1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18370868 15057743 2606351
EPAS1 ARNT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9079689 11018023 19845609 14668441 33591636 24981860 32461361 15192019 16181639 23275444 23434853 26160453 23796364 19129502
TP63 ARNTL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
ARNTL BHLHE41 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16685415 16267380 15147242
RORC ARNTL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18454201 23555304
RELA BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18226221
HIF1A BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020
CLOCK BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19032342 14672706
BHLHE40 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15975549 22610404 11879638
BHLHE40 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23423709 21506129 22905217
HIF1A BHLHE41 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020 12354771
MYC BRD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19111069
CHD3 NR1H2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17003465 24192518 16917063
NPAS2 CRY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17660446 11441147
PRKAA1 CRY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21892142
CSNK2B RXRA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSNK2B UPF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ENO1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18490439 19219071 2191300
ENO1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
STAT3 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15223310 22313388 16651438
MYC FXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
SIN3A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12724404 24981860 14593184 26496610 11102443 17827154 10220385 14647463 9885572 15695521 12398767 26344197 21258344 9804427 16331260 12091390 9150133 11602581 10640275 12920132 9790534 17643391 12943729 19182791 25314079 12374985 28514442 26949739 10444591 11931768 11171972 17956988 12453419 15451426 23752268 11784859 18059533 20585571 9520398 11118440 17962807
HIF1A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24015760 16511565 21148070 11641274 17273746
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HIF1A RORA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15270719 14742449
HIF1A PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18461556 19490906 11879638
ID1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17426247 17145808 23657791
IFNG STAT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12040185 7796299 8156998
USF1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8900159 21050451
NR1H3 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23686490 16484597 24438183
IFNG STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10707961 11960596 28264935
VDR IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20691220
STAT3 IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10068671 24159173 11368440
TP63 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11714701 9405685 12374749
PPP2CA MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983168
MDM2 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20571051
TP53 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18431400 15781865
TP73 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11309270 18829110 21245298
MYC NFIL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
NR1H2 VIM â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR1H2 NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12470667 11875109 22194611
RXRA NR1H3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20682316 12117567 8621574 15604093 15722453 9013544
STAT1 NR1H4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19393742
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
STAT1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16481475
VDR RXRA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10733574 15604093 12847098 17500032 17786964 12796488 15829977 15647825 20153625 11075811 15888456 9632709 21988832 27728806 15890193 10224118 16750418 16357103 11514567 20564192 14726489 15805579 26329759 11149488 11124027 21478865 10037600
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
STAT3 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16107692 23874455 20043094
TP53 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16462763 16651407 18431400
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
PRR20C VENTX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRR20D VENTX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRR20E VENTX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRR20A VENTX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PRR20B VENTX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NR1H2 RXRA â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
EZH2 PHF1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PRR20A PRR20C â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20B PRR20C â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20C PRR20E â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20C PRR20D â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20B PRR20D â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20A PRR20D â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20D PRR20E â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20A PRR20E â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20B PRR20E â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CSNK2A2 CSNK2B â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PRR20A PRR20B â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
IL10 KRTAP1-3 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CHD3 HDAC1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
PPP2R1B PPP2R5E â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
ARNTL PER2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PPP2R1B PPP2R5D â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
RXRA RARA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5212283 10698945
BYSL NOC4L â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
ID1 TCF3 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CLOCK PER2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
HIF1A ARNT â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 12391259 10085255 16954218 7836384 17916562 26496610 8663540 34592152 14764593 20603618 14668441 21512126 11606485 26350169 9079689 24056783 19845609 27684187 11782478 19168635 23363003 26160453 28628118 15850782 17197389 21620138 15833858 23086815 24434214 20458141 18024476 23458834 12810720 28514442 15347669 9704006 27320910 20562859 11829741 15031145 21435239 20049704 15479785 20932347 12393189 11025203 16861921 9159130 10671489 16520375 15615775 17213817 28205554 23796364 15319539 11593383 19251694 20699359
ARNTL NPAS2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CLOCK CRY1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CSNK2B CSNK2A1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 36833176
MDM2 TP73 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PPARG RXRA â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RXRA VDR â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RARA RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ARNTL CRY1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NR1H3 RXRA â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
CRY1 PER2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPARG PPARGC1A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1A PPP2R1B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1A PPP2R5E â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R5E â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ARNT EPAS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ARNT HIF1A â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ARNTL CLOCK â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CSNK2A1 CSNK2B â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CENPX FANCM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22510687 20347429 20347428 18174376 17289582
RELA CXCL8 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15079071 15536066 17550372 19171876 23430059 8383323 9743347
RELA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 129.0 1.0 Omnipath 12820969 24337575 15289496 9405619 9698090 20038977 15057743 21665565 24260304 10817569 14631383 10969814 15005855 19668231 16325549 19732956 8207232 18281166 27856305 23894194 9388261 26340924 10975857 10745031 20194077 10928981 16553947 17565687 16764699 22848596 15531761 16105834 16803583 9510190 15355994 18221537 12643600 20053934 11716760 8617886 12218154 12707271 23637609 27076634 8878392 17917246 12163591 16829531 16818736 14670967 12038622 15958549 18362169 8413215 19734226 23386688 11297551 15950427 17362989 16455661 27371733 11953364 8413306 18074095 11973337 18786178 19376732 19837667 17276517 15517885 11342414 18669446 7876168 15350531 14645117 22891766 18034886 11564889 12748173 17586662 18996370 15223809 17041011 12485925 16004996 15079071 21343296 26618242 18435575 17636245 22340043 19173296 24634218 11120852 10477716 21343177 12058956 17045242 19786024 24048734 24770886 10202011 18309103 11864912 21131967 19064995 10530453 12716652 16418726 28283022 18723827 17040605 21255844 15615716 17932106 19966855 20696864 15387324 21451502 15722553 15879558 12855659 12883201 15688424 18045535 10506755
PPARG CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19395102 18485432 20107546 20554962 16303327 20889551 15331599 12695526 15720834
HIF1A CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17082639 19491109 17488804 21925595 23144021
TLE5 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10660609 16713569 15489227
ARNT VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15930297 18372249 17413038 21814878 7641334 22306343 19020709 23086815 16774940 8756616 10702253 22076197
CSNK2A1 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16129408 18669648
ARNT VEGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 7539918 17987801 1823643 16716598 12829734 9159130 13130303 9746763 12080085 11566883 10403805 7768934 8943284 15451019 11528470 9278421 16887934
ARNT HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17213817 8816435 17197389 14764593 12393189 12810720 15319539 23363003 9079689 11829741 15479785 26496610 12391259 17916562 24434214 11606485 20562859 9704006 21620138 11782478 20932347 15347669 8927054 21435239 19168635 9159130 14668441 20049704 20603618
CLOCK ARNTL â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16687287 16020918 19341811 11798163 16507766 22936566 19605937 17204240
RORB ARNTL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18418469 24737872
RORA ARNTL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15312644 15312651 22244086 20211758 15821743 24737872 20817722
ARNTL CRY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17660446 20215567 22750052 18433872 20817722 16628007 20852621 11441147 11798163 24089055 18728219 19605937 14581485
ARNTL CLOCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12691740 16980631 16687287 16020918 19341811 16507766 22936566 19605937
ARNTL BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19032342 14672706 16267380
ARNTL PER2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20576619 23620290 17660446 20215567 19168071 22750052 21960634 24051492 23469106 20852621 11441147 11798163 22039518
CLOCK ARNTL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23555304 9989497 26164627 11439184 14701734 11018023 19922678 31515488 20551151 32296183 9576906
PER2 ARNTL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18662546 20159955
RORA ARNTL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18454201 18662546
CRY1 ARNTL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 18662546 23555304 10531061 25756610
ARNTL CRY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23555304 10531061 25756610 19106159
USF1 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12684442 16006741 12114522 18310887
RELA BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22967044 20018891
BHLHE40 BHLHE41 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14672706 16462771 16267380 12624110 15147242
TP53 BHLHE40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22723347 17347673
CLOCK BHLHE41 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16685415 14672706 15147242 16267380
BIRC5 BUB3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
HIF1A BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22925504 16847054 19245702 23732337
TP53 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 19363521 19470765 19067706 17124180 11714700 16432013 18698017 21443519 12235242 20236666 22266808 16595680 15361831 23838170 17916908 15087401 15377848 19018856 19439469 22503977 17699779 11965534 15657147 18022393 18027854
RELA BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17553314 20126979 14739605
MYC BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17170079 19287963 20508797 19602047
STAT3 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19880237 26512963 15184887 15469392 16651438 18242580 16397018 21344490 20826784 24431073 15077160 12393476 19284568 17880940 17533050 17932422 22984561
TP53 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19211844 11965534 11714700
RELA BTRC â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
TP53 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 24189068 8702807 10669755 22270849 12808109 17942917 19086036 20731879 16061648 20554748 24460719 11798189 10082575 15205322 18769160 19800042
RELA CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17673602 18226221 10464245 18566231 19800042 18174238 15755876 18341653 11861406 20103608 12894581 17098279 22306268 20922712 16998474 10409765 19766095 15756023 21056029 22835384 17407600 15870875 18184402 17944672 15856023 20538607 19263436 16453001
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
STAT3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16510571 19880237 17997399 15469392 16651438 21163886 22566696 16912181 22349830 16384639 12147685 21344490 20160059 19506034 20332458 23329648 11114718 17761947 22218594 15994929 21172343 18988190 18177723 24499623 21435102 19926637 18184402 17344214 22313388 23950841
HIF1A CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23455892 20360945 20179204 15991006
PPARG CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23455892 18927468 14764597 15486348 11287611 20651819 15041706 19075513 15193259
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
TCF3 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
CLOCK CRY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17660446 22750052 18433872 20817722 20852621 24089055 11798163 18728219 19605937 14581485
CLOCK PER2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14672706 17660446 19168071 22750052 21960634 24051492 23469106 24498074 20852621 11798163
HIVEP1 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15456958 15778499 14764936 10825206
CSNK2A1 CORO1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23410663 22355754
CSNK2A1 DVL3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
CSNK2A1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 34049972 15016307 10938077 27630163
CSNK2A1 NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16904112 18250151 25825525
CSNK2A1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17287340 19413330 22113938 18669648
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
CSNK2A1 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8384219 17368182 8622969
CSNK2A2 DVL3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK2A2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17570479 17287340 19413330 18669648
CSNK2A2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16083285 1088347 10348343 10884347 16552184 9315650 10747897
CSNK2B DVL3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10606744 11709713 10214938 10951572 16713569 11551930 10747897 10673501 11883897
USF1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14742674
RXRA CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19712670 18400206 16608838
VDR CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22939842 11991950 18400206 11723248 19712670 12167569 19581388 15358113 12147248 15205382
RELA CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19002106 16608838
NR1H3 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21963511 11179691 17054913 16260782 12917410 17660447 10403849 9013544 14960721 17690173
VDR CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19106115 17054913 20371703
RXRA CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19106115 20338915 16049268
DVL3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
HIF1A ENO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 8955077 15459207
ENO1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10082554 10528225 17595061 10802057 19846662 11134351 23421821 10403782 18490439 14506152 20886042 7880838 2005901 9074493 18070418 21559732 9119380 20412594 10681589
HIF1A EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20513003 18174278 16924414 19030186
EPAS1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15156561 15192019 19010893 15191799 19080330 20061373 9113979 16900513 20574527 10531360 21057546 21145972 11350893 16778202 23213445 11301389 20807755 9746763 9665461 11751212 12750296 24062466 11912213 16920734 17322369
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
EZH2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22563434 21674483 17911618 21624129
TP53 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10101800 12788915 15580300 16317104 16322229 14719118 16557594 20797428 11103825 19615968 7539102 12447615 12944915 12963547 11313989 16951143 9841917
STAT1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11309387 19262492 16317104 14602726 22805310
TP73 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18343378 16741250 15805279 19615968
RELA FBXW11 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10321728 9990852 10066435 9859996 10514424 10230406
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 20124407 11684023 11285237
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
IFNG HIF1A â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
HIF1A VEGFA â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21372296 21765015 22006996 22461508 22850421 22988108 23390297 24006507 25043024 25103413 25732824
STAT3 HIF1A â—¼   DOWN_REGULATES ✅ - 24.0 1.0 ACSN 10347215 10973499 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 18985005 19380816 20093776 20237412 20406969 20581311 21840487 23124025 23454751 23953057 24857661 27216177 28186502 7543512
RELA HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18498249 17898080 23185316
STAT3 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19265129 18644974 16007214 20924113 17597020 23991099
HIF1A PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835053 20724477 14726529 11359907 16682453 15833446 16982770 16618748
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
HIF1A VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 186.0 1.0 Omnipath 20303950 17085645 22609851 12697836 17557905 15140752 17431122 17486380 11866451 20453883 8756616 18027712 10702253 11678207 19046997 19491109 20127031 20307196 15315159 11359907 18233956 12032158 19502554 9178256 15956714 23060442 11350893 15930297 15207747 19074414 20660740 20489156 17089387 15735682 16506055 9746763 21793044 20436213 22789427 21814878 17053163 18835464 18072084 15983061 11749701 20875806 18432192 18471962 15039660 16750526 17322369 16052307 12433987 21447827 16682453 16971129 21258402 20027628 12542982 17272396 20574527 14712484 16865543 17916562 19664474 23354733 18060642 12570801 9235919 22903062 18563715 12154035 12612059 20599538 18572865 21187066 10837481 16596228 12963476 19828020 15169887 15156561 20232316 16969516 15111179 15342781 15475194 9398602 11001829 11191064 10882714 8387214 15191799 12820439 17413038 19111391 16854277 12509854 23404377 16900513 24347168 18021292 17947829 22771629 18295594 15774498 12205045 17498666 11007955 14699103 21145972 16618748 18322419 16540671 20724477 16778202 9393757 11549290 17065555 15315937 18024476 21343542 15705785 10987301 22306343 23086815 16774940 19420388 15050899 19759417 18289162 10415537 15277220 16818499 16982770 24464787 19238077 23028984 11056102 15838297 16301840 18578647 18702304 19020709 19564336 17461470 16515634 20043814 15806152 19336759 22750006 23185615 17470361 15746177 17889387 18339855 15890092 15663958 17704802 10477681 12052835 15382039 11707426 12855680 12023962 20432243 10611972 19819950 9359410 10640274 12393646 16311927 21435239 16357173 21731766 16543242 17481912 20449875 14602779 17167225 11486006 18294451 22076197 17999410
STAT3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15735682 18985005 10973499
MDM2 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15880652 25535359 12606552 25447306 17234751 19696166 10640274
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
HIF1A VEGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7768934 11528470 9278421 17987801 16716598 12080085 10403805 16887934 7539918 1823643 12829734 13130303 15451019 9746763 8943284 15369676 9159130 11901189 22952674 11566883
VEGFA ID1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15501236 15520864 15573129 16002046 16076871 16572188 17086423 19414323 21372296 22064427 22461508 23390297 24346288 26201938 8837607 9157999 9570538 9753319
TCF3 ID1 â—¼   UP_REGULATES ✅ + 7.0 1.0 ACSN 15169839 16831886 17018611 17299729 17490644 18832382 22564737
ID1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 12145280 9242638 15029197 8380166 20195544 9528857 1922066 18674781
STAT3 IFNG â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 10347215 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 19380816 20093776 20237412 20406969 20581311 21115385 21840487 23124025 23454751 23953057 24857661 27216177 28186502 7543512
IFNG RELA â—¼   ENZYMATIC_REACTION ✅ 48.0 1.0 ACSN 10485906 10679398 11489965 11579131 11777960 11870632 11964313 12133954 12413632 12759422 12818165 14607900 14668329 15079071 15536066 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17145890 17404308 17550372 17559085 1825141 18272812 19171876 19833085 20038811 20138012 20819927 21149606 21224476 21411734 23430059 24658051 26755705 2965306 6425450 8383323 8580069 8641346 9743347 9834059 9864217
IFNG IL10 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
IFNG STAT1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11489965 11579131 11777960 11830590 11870632 11875494 11964313 12193701 12223527 12413632 12433365 12796776 12811837 12818165 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15634932 15644117 15699106 15778339 15811952 15814715 16127449 16286920 16424049 16713974 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 1825141 18272812 18345002 19833085 19879327 20038811 20819927 21097505 21149606 21263073 21411734 21930765 23390297 24658051 25960930 26755705 2965306 6357187 6425450 7594497 8683106 8871614 9834059 9864217
IFNG STAT1 â—¼   DOWN_REGULATES ✅ - 69.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11489965 11579131 11777960 11830590 11870632 11875494 11964313 12193701 12223527 12413632 12433365 12796776 12811837 12818165 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15634932 15644117 15699106 15778339 15811952 15814715 16127449 16286920 16424049 16713974 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 1825141 18272812 18345002 19833085 19879327 20038811 20819927 21097505 21149606 21263073 21411734 21930765 23390297 24658051 25960930 26755705 2965306 6357187 6425450 7594497 8683106 8871614 9834059 9864217
STAT1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 12759422 14735146 26170288 8823363 1833631 8647290 7619083 11416037 12130529 16162660 21178011 9218597 12493643 17283162 15217838 10830295 24200694 7957928 19476491 9271410 19262492 7565811 9880553 17878383 9748323 21039465 17016440 10881178 21530491 17270146 12052885 15055356 10201928 18616672 13678429 19124156 9491997 24478085 8509377 8990168 12893768 16380218 23740952 17105733 16195385 23419754 19935876 7796811 17558024 19929594 10713330 23645984 9548487 11390994 12223098 15931263 17689680 18802113 18787082 10440232 20004484 10373559 10585866 10707961 12403783 23582260 10982806 9059994 16785492 22767256
RELA IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17035338 12759422 12105194 21243522 9374532 10227974 20643337 19929594 19732956 21224476 23195252 23667107 12842891 14662860 12757742 18690006 17407192 10075983
IFNG STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 29796172 23285134 18566411 28430601 28143527 24366643 24608040 17947699 25950470 19846878 27378243 18950705 27570112 15051500 17986321 26467650 23657944 20087684 9649436 22823229 14517275 22178447 22425562 23352233 23562842 28445952 11960596 17997851 24443556 26934444 24777831 11972023 12725866 26113305 22162832 29925830 10707961 23840250 25753288 9454765
IL10 STAT3 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
STAT3 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21398617 18403020 10903771 25108026 24315995 21157434 12857749 28011648 31886314 18765795 19124156 18848473 12817009 16606674 21385272 21041726 28713870 22378047 15034082 17404037 15972681
STAT1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18292493 19703987 21398617 19124156 20709027 12817009 21041726
NFIL3 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21460847 23028054 28100679 21383239
RELA IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18760861 9310124 19124729 19122653 18077329 22070873 27324129
IL10 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24513872 20681025 29682323 25512602 19890111 25762897
IL2 IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
RELA IL2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10679398 12133954 12759422 14668329 15079071 15536066 17145890 17404308 17550372 19171876 20138012 21224476 23430059 8383323 8580069 9743347
MYC IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8962093 10702306 12695333 1349016 9417120
PPARG IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19217272 16611855 10671476 15187132 11726648 19712756
RELA IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 7623820 8814256 22427656 9417120 9605137 15477007 9111330 21832163 9135552 8383323 8934574 11035116 7730629 16275766 9737979 19968887 28199730 1604322 15585831 8977179 12027419 18045535 18207244 17179947 23578476 15710339 9233628 11145913
IL2 IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 6815536 3095922 15265897 12649439 16477002 15933202 1940342 17032757 15178252 8260650 3116143 8894436 1993646 8580082 8960125
RELA IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23144749 9135552 11781710 7636248 8430069
ROR2 MAGED1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 16713569 12754255
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
TP73 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20921405 15734740 20156675 10469568 11245471 10207051
UBE2I MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 18499675 17700533 26025930 25417702 19218448 21088494 10321734 10469568 10435614 20588255 25301064 10207051 11223036 21261729
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
MYC VEGFA â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
MYC VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19738061 19147754 17785433 22002305 18809243 19398483 12368264 23028984
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
TCF3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
PPP2R5D MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
PPP2CA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151 15048125
TCF3 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9242638 1649701 10915743 9001211 9184158 9050988
NPAS2 PER2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22039518 17660446 16636276 11441147
NR1H2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 15604093 21071413 24561505 9199332 7760852 16189514 18988627
PPARG NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11604492 16959872 24751522 14703507
RXRA NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20682316 12117567 23331499 15722453 15604093 21071413 9013544 18988627 10890879 8621574
RXRA NR1H4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
RXRA NR1H4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 19883617 7760852 10744760
VEGFA PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
TP53 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10321740 19763735 21057544 18661553
STAT3 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733515 24218138 23963458 15793565 16293640
PPARG RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12878983 18715135 20589837 12704187
PPARG PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16513826 32991581 29182484
RXRA PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 12763030 25609649 20211142 11877444 16504037 17579352 16713569 9065481 22205725 23331499 22363753 10854698 19147680 19043829 12591919 9568716 10882139 10935544 17980149 26260846 21478865 14587029 23711995 9121466 18217139 31547433 7838715 19047629 23275339 21833030 12966085 17312272 11237216 15888456
UBE2I PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19692572 15507114 26192107
PRKAA1 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20640476 17609368
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PPP1CB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16501611 15178317
PPP1CC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17274640 15178317 16501611
PPP2R1B PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18715871 17540176 19114990
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11591705 12842894 17188031
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
PRKAA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28797070 15866171
RARA VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15613498 17470563 18326047 11804877
RARA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 15528208 19345331 16713569 16769902 21988832 23331499 14521715 15604093 21071413 10828175 10698945 18988627 12393611 25303530 16224062 25241761 1310351 21478865 17641689 7760852 9415406 9121466 7705655 9582446 15171703 10882070 1314167 12052862 31700049
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
RELA VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18184402 17673602 16684540 15517885 12160329 15856023 18056465 20538607 17407600 20103608
STAT3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19345327 12057007 23335796 16713569 18448488
VDR RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 14726489 16357103 17786964 16750418 11514567 20564192 11149488 12796488 21988832 12847098 23331499 15604093 10037600 11094341 9632709 20153625 21478865 10733574 11124027 15829977 10224118 17500032 15805579 22179700 15888456 15647825 11075811
STAT1 STAT3 â—¼   DOWN_REGULATES ✅ - 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19122651 17558387 22693070
STAT3 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 25609649 8662591 12070153 31462771 25241761 11722592 8710878 9794795 23268184 15284024 16189514 9535918 11594781
STAT3 VEGFA â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
STAT3 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 22076197 19880237 12824281 20232316 18320073 20482858 17557905 21354136 19020709 17937859 20880395 25101566 16007214 19284568 19336759 20236940 10744750 11960372 15688401 19082717 21344490 20939432 17533737 21733558 18021292 20720018 11744720 23104276 16540670 11960378 20043094 21278793 21418908 15665043 15735682 21172343 23756865 20052595 17169602 18184402 21731766 23911788 12545153 22313388 16899623 20709526 18408167
STAT3 VEGFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17987801 16716598 13130303 7768934 11528470 9278421
TP53 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 8108142 20639906 9377555 21325822 16684540 9833779 10910082 16835303 23449391 8521408 15860260 11971180 11559575
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
TP63 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16462763 22521434 17716971 19622632
TP53 FBLN1 â—¼   KO_UP_REGULATES ✅ + 1.03 1.03 PKG 28854368
FANCM TCF3 â—¼   KO_UP_REGULATES ✅ + 1.17 1.17 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368