Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NR1H2 BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19032342
VDR BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23220548
NR1H3 BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19032342
BHLHE41 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15066123 17660447
BHLHE41 DBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15066123 14672706
PPARGC1A CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16891307 16488887
JUN CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11278771 16729332
KLF9 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9875228 10627496
SREBF1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15123650 16885156
SP1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9875228
NCOA1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16891307 15143151
PPARG CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
NR1H2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12917410 9013544
HLF DBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9571207
FOXO1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21149440 23430617
FOXO1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16670091 19289458
NR1I2 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17684529
NR1I3 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18391971
FOXO1 NR1I2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17684529
RARA HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11585914
NR2F2 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11981036 18474611
HNF4A PITX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1312668 9651383
JUN SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
JUN PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16729332 20143420
JUN VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15930183 17121851
RXRA NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17673910 5223765
SREBF1 NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15123650
NR0B2 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18385139 16213225
NR0B2 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20375098
NR1D2 NR1D1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19682428 9482666
PPARGC1A NR1D1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17476214
PPARG NR1H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
PPARA NR1H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1H2 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1H2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
RXRG NR1H3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
NR1H3 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17054913 22279938
PPARG NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1I2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
PPARA NR1I3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20208394 17962186
RXRG PPARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPARA PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17275789 22033933
RXRG RARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD3 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22610349 23161884
HNF4A SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15651981 16713569 19115260
VDR SMAD3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11278756 10037600
PPARA RXRG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16169070 22205725
PPARG RARA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 32929351
RXRG RXRA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NR1D2 NR1D1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 15604093
HNF4A NCOA1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HNF4A NR1I2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15331348 16455805
NR1I2 RXRB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15604093 16189514 9727070 23536728
VDR RXRG â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15604093 32296183 20211142 15919723
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
PROX1 HNF4A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16488887 15604093
HLF DBP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23661758 21988832 10073576
NR1I3 RXRA â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
HNF4A FOXO1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12519792 19740748
NR1I3 NCOA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 15572376 15604093 26186194 28514442
RARA RXRB â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RXRB PPARG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20211142 22205725 25609649 15604093 30699358
RXRB RARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20211142 32296183 29892012 15604093 26871637 21988832 16713569 28514442 16189514 25303530
RARA RXRG â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HNF4A PPARGC1A â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPARA RXRA â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HNF4A NR0B2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
NR0B2 HNF4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16455805 20516075 10594021 16488887 15604093 28128295 11535594
NCOA1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10567404 10847592 9642216 16713569
SP1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25879517 16478997 17215518 16713569 33572115 10506225
RARA NR0B2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8650544 16189514 9773978 16713569
NR0B2 NR1H2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12198243 16189514 27485016
NR0B2 RXRA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12198243 21988832 16189514 10594021
NR0B2 PPARG â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 19596656 11696534
RARA SP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10361124 19401466 16713569 18270252
SP1 RXRA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10361124 10393239 16713569 18270252
SP1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10878024 11114293 22227581 12228247 11432852 16714330
PROX1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15205472 16488887 23626788
PROX1 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16488887 15604093
BHLHE40 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15975549 22610404 11879638
NR2F2 HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10331424 8622679 9111350
RXRA HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11027556
RXRA HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10744771 11027556
SMAD3 JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10903323 10220381 11306568 21829441 9732876
SMAD3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
JUN NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15292277 12842887 19322021
RARA NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12138096 16456540 9192892 23975195 9121466 10454579 16606617 17475621 21478865 17363140 20543827 17641689 16713569 10082574 10760302 12665583 20338915
NR1I2 NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15331348 16455805 12072427 17429319 19171678 18096694 23602807 23160820 15604093 12909012
PPARG NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10347167 15604093 15026545 30813326 11877444 19596656 17704298 30595551 9041124 9121466 9744270 23178929 10339548 16713569 15888456 17513608 22070604 17449869 10731636 20717101 10848596 17468099 11027271 17312272 11500849 23975195 17011503 16373399 10944516
NCOA1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16891307 19194461 18511507
NR1H3 NR0B2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12198243 16189514 27485016
RXRA NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23546875 19111018 15202934
NR0B2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24038081 16803864 11696534
NR0B2 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20185821 20375098 21081708
NR0B2 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 11369442
RXRG NR1H2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR1H2 NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12470667 11875109 22194611
RXRA NR1H3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20682316 12117567 8621574 15604093 15722453 9013544
PPARA NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18758514 12595494 18498712
RXRB NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26871637 32296183 15604093
RARA NR1I3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20211151
NR2F2 PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11981036
RXRB NR2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 10900149
RXRA PPARA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15888456 12562861 7760852 34081964 10195690 22205725 23711995 16189514
PPARA SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12730331 1273033 21540177
RXRB PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8384714 23331499 11237216
PPARGC1A PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21775429 10669761
SIRT1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15850715 21633182
RARA SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21310893
VDR RXRA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10733574 15604093 12847098 17500032 17786964 12796488 15829977 15647825 20153625 11075811 15888456 9632709 21988832 27728806 15890193 10224118 16750418 16357103 11514567 20564192 14726489 15805579 26329759 11149488 11124027 21478865 10037600
SP1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23843607 20160399 23704280
SP1 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10919269 15664452 10845704
SREBF1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11875060 19048273 22031849
NCOA1 VDR â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
NR1H2 RXRA â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PPARA PPARGC1A â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
NCOA1 NR1H3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
NR1H2 RXRG â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
NR1H3 RXRG â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RXRA RARA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5212283 10698945
NR1H2 RXRB â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
NR1H3 RXRB â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
NR1I2 RXRA â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NCOA1 PPARA â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 NR1I2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PPARG RXRA â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RXRA VDR â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NCOA1 RARA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RARA RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NCOA1 PPARG â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NR1H3 RXRA â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
NCOA1 RXRA â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
PPARG PPARGC1A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
BHLHE40 BHLHE41 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14672706 16462771 16267380 12624110 15147242
HNF1A CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15933209 10403849
NR0B2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 19346330 15314177 23038264 21566081 18323469 19805516 11030332 20375098 15358835 15817812 21817852 12525500 21963511 17145766 17654698 19085950 19056864 16049268 15581596 11518759
NR1H3 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21963511 11179691 17054913 16260782 12917410 17660447 10403849 9013544 14960721 17690173
PPARA CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10744771 11042130 10777541 17660447 14960721
NR2F2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10627496 9092518 10403849 9799805 23458092
NR1I2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15629111 15322103 15331348
VDR CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19106115 17054913 20371703
FOXO1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21817852 19463968 16885156 19237543
RXRA CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19106115 20338915 16049268
HNF4A CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 23626788 23038264 17920062 10627496 17603092 21963511 15933209 9013589 16488887 16492670 9799805 15331348 17660447 16049268 11402042 17636037 15322103 16323215
FOXM1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9013589 15933209 9799805
NR1I2 DBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19129222
FOXO1 PPARGC1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 10364186 15668399 16122419 19449109 25464856
FOXO1 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24478438 16492665 18202130 20868688 22511764
PPARA FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16985262 18391971
SIRT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 24003218 22013015 14976264 18235501 15220471 14980222 22395773 15788402 15692560
SMAD3 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18391971 15084259
HNF4A FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12519792 19740748
FOXO1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16670091 12966085 17317207
HNF4A HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8367288 9111350 9792724 8674436 11717395 9313764 9837989 9204893 9232592 1734282 20850486 8735941 11145965 11085951 10331424 8808405 12601360 16670373
NR0B2 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11535594 12716764 24318876 14672953 11679424 21725089 12601360 10594021 16527247
SP1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19540905 15651981 23307400
HNF4A NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12774017 15331348 12601364 18305375
HNF4A PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11981036 15912134 19933841 17022998
NR0B2 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11535594 23331499 15604093 21071413 20516075 16488887 16455805 14672953 10594021
PPARA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10542237 17360982 18754816 15838301
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
JUN TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8058069 16327802 16730810 23437118 8183578 16365456 22429882 23936544 15546613 10843986 16978906 23762330 7521696 8631909 12794825
SMAD3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9732876 10220381 11306568 21829441 10903323
NCOA1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11698662 10731636 9626662 12163133 21775429 15888456 9407140
NCOA1 NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20682316 25962847 15604093
NCOA1 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12612084 23975195 17786964 15604093 9878542 11124027 11149488 9121466 12403843 12796488 10224118 11075811
NR0B2 NR1I3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 14963109 8650544 9773978 15000748
NR0B2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 23331499 16189514 12198243 10594021
NR0B2 NR1H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12198243 23331499 16189514
NR0B2 RXRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 16189514 10845098 10594021
NR0B2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 8650544 9773978 16713569 11368516
NR0B2 NR1I2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12805410 23331499 16455805
NR0B2 NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 16189514 12198243
PPARG NR1D1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12821652 15733732
NR1H2 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16644917 11287605 16825483 19258656 26120082
RXRB NR1H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 15604093 10187832 14993927 16189514
NR1H2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 15604093 21071413 24561505 9199332 7760852 16189514 18988627
PPARG NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11604492 16959872 24751522 14703507
NR1H3 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 18854425 19366697 16831124 19933273 24277692 18202130 20868688 16112614 26120082 15855229 12730331 24265317 21094755 22511764 19716432 21266776 11287605 11694526 18420801 22984430 18684130 24458133 21540177 21979752 19258656 15330762
RXRG NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25910212 15604093 25416956 21516116 31515488 32296183
RXRA NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20682316 12117567 23331499 15722453 15604093 21071413 9013544 18988627 10890879 8621574
NR1H3 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 24713062 21071413 16189514 14960721 8621574
NR1I3 NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10924340 15557560 14683479 22363234
NR1I2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 9727070 15604093 11706036 9489701 16189514 26855179 23160820 22976785
NR1I3 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8114692 23331499 12130689 12896978
NR2F2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 7479078 8119938 10900149
NR2F2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 23331499 10098492 20592862
PPARA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12941763 16226723 20706641 17261671 18769491
RXRA PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 10195690 12562861 16189514 11237216 10708554
PPARA RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22205725 23331499 16169070 15130092
SMAD3 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 12457461 12524424
PPARG TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 14702344 17625041 31023188 17995524 16321227 18615188 14693716 12711314 16611854 18991162
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
PPARG PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16513826 32991581 29182484
RXRA PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 12763030 25609649 20211142 11877444 16504037 17579352 16713569 9065481 22205725 23331499 22363753 10854698 19147680 19043829 12591919 9568716 10882139 10935544 17980149 26260846 21478865 14587029 23711995 9121466 18217139 31547433 7838715 19047629 23275339 21833030 12966085 17312272 11237216 15888456
RXRB PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22205725 25609649 23331499 20211142 15604093 11237216 18988627 10882139
PPARG RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12615696 16189514 18988627 15130092
SIRT1 PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15205477 15744310 15989956 18687677 19590512 19960022
SIRT1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23142079 21633182 19553684
SIRT1 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15744310 20640476 24003218 19553684
SP1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740727 7585542 15831516 9626663
RXRG RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 21988832 25910212 25303530 23331499 20211142 15604093 21071413 10529278 21516116 25416956 31515488 16189514 32296183 16713569 18988627 29892012
RXRB RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 21988832 26871637 25303530 23331499 20211142 15604093 1310351 21071413 10721822 31515488 16189514 32296183 16713569 18988627 29892012 1310259
RARA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 15528208 19345331 16713569 16769902 21988832 23331499 14521715 15604093 21071413 10828175 10698945 18988627 12393611 25303530 16224062 25241761 1310351 21478865 17641689 7760852 9415406 9121466 7705655 9582446 15171703 10882070 1314167 12052862 31700049
RXRA SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11287605 11694526 17531980 16112614
RXRA TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18615188 8264664 16611854 18007025
VDR RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 14726489 16357103 17786964 16750418 11514567 20564192 11149488 12796488 21988832 12847098 23331499 15604093 10037600 11094341 9632709 20153625 21478865 10733574 11124027 15829977 10224118 17500032 15805579 22179700 15888456 15647825 11075811
RXRB VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 23331499 15604093 10721933
VDR RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11713233 15604093 15919723 32296183
RXRG VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11713233 15604093 15919723 32296183
TGFB1 SMAD3 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
SMAD3 SP1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
TGFB1 SMAD3 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
SMAD3 SP1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
TGFB1 SMAD3 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
SMAD3 SP1 â—¼   ENZYMATIC_REACTION ✅ 47.0 1.0 ACSN 10454538 10964912 11007770 11013125 11013220 11074002 11114293 11279127 11283613 11283614 11376132 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21098712 21252118 21614932 2191300 22331441 22652804 23140366 23338822 23784029 23869868 25374926 8515656 9312026 9389648 9618481 9670020
SMAD3 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26553048 27974707 10708950 19214138
TGFB1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21557273 24899689 24075003 24485922 28756206 32196115
SP1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12186868 9580699 2808430 12615726 22415074 27974707 12138160 10964912 9242631 15178441 23437118 23936544 11114293 8325508 16714330 11278686 10212284 9837963 11054406 23806282 15979845
SP1 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19716432 20971080 20179320 24458133 18068676 17449871 15462672 21696544 15330762 22511764
SP1 SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 18068676 10224053