Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RXRA APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1321332 9392425
FOXA2 APOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7961760
PROX1 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19264593
FOXM1 G6PC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15933209
ABCA1 RXRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18782758 21507939
NR0B2 ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12198243 22424975
FOXA1 ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24807696
NCOA1 ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14764426 15774904
RXRA ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12145812 21689630
HNF1B ACE2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24100303 16297991
ATF7IP ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
FOXM1 AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9891062 12215259
NR5A2 AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12865342 8668203
FOXA1 AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14521963 10455192
DBP AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7518671 2958390
NR0B2 AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19887897 14672953
CEBPA AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19564408 24191285
AGT ANPEP â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 15687497 17803194
HNF1B AKR1C4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12220531 2044952
ALB YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
FOXM1 ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1990282 10542313
FOXA1 ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8455618 14521963
HNF1B ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671480 1673926
HNF1B ALDOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8383844 7843280
YWHAZ ANXA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
NR2F1 APOA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1639815
APOB MTTP â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8626595 14732096
NR2F2 APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9580705 1639815
PITX2 APOC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1312668 1639815
ATM YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RUNX2 AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19585539 23300083
HNF1A B3GALT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12855703 14534330
BCL6 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23160044 12402037
BCL6 IL17A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19631565 20212093
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
FOXA2 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20160041
GATA3 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20189993
SIRT1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22249256 21640770
TCF7L2 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17468517 18655789
GATA3 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19700764
CDX2 S100G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15217781 8665895
CDX2 DPP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21284881 16480684
PPARD CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20097210 19347285
HDAC1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16431920
CEBPA HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2247079
CEBPA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24429361
CEBPA SLC10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11031103
NR2F2 CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20592862
HNF1A CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19782160 17848139
FOXA2 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24440874
FOXA1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24440874
CIC YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
MAPK1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8941362
HSPA5 CRP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
POU2F1 CRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22750226 16116232
CSNK1A1 YWHAZ â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 12062430 5215475
NCOA2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21772333 19213727
CTNNB1 PPARD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11943708 17724465
CTNNB1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22552774 12750294
NLK CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12556497
SIRT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27776347 28583374
HNF1A CYP27A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11406622 10528998
ESR1 CYP2C9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24960263 21493749
NR0B2 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22982774 16455805
NCOA1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16891307 15143151
HNF1B DPP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16297991 16781669
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20339243 21467818
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
FOXM1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346 17875680
POU2F1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18000219 20215511
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
ESR1 PTPN6 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673088 7539106
HNF1A ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11522780
FOXM1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346
PROS1 F8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 7620160
HNF1A FGL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19304666
STAT3 FGL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19304666
FOS MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
FOS MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
FOS INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9270011 12516092
FOS HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11719466 10472808
FOS FOXA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22577344
FOS HSPH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20188076
FOXM1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16965535
SRC FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17160021 22105363
FOXM1 FOXA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1732730 9602135
FOXA2 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951069
FOXA2 GCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20576918 11875061
FOXM1 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7524494 8817653
PITX2 FZD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20051274 18715140
RBPJ GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15356142 17658279
GATA3 TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951069
NR0B2 GCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14752053 19366697
RXRA GCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11872666 14749268
HNF1A GSTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14561216 15155840
NR0B2 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17895379 0706736104
HDAC1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20609221 22422937
HDAC1 RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9694793
NFIC HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11245470
HMGB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18218727 19158276
NR2F1 HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8622679 9111350
HNF1A SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11522780 19901966
HNF1A S100G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15217781 18032476
HNF1A IAPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14521933 15566941
HNF1A SLC5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17962340 11269503
HNF1A SLCO1A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20576918 17724432
HNF1A SLC23A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20471816 19741195
HNF1B SERPINA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10330009 3263567
HSPA4 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSPA5 SLC22A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA5 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ HSPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
IL17A IL17F â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NR0B2 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21817852 17259388
KAT2B RBPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10747963
LDHA YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
RPS6KA1 MAPK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MAPK1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15778365
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK3 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
NR2F1 MTTP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20007910 22357705
NCOA3 NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17476305 5219902
RXRA NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17673910 5223765
NCOA2 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19305643 10454563
NCOA2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19805480 16483936
NFIC PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10085123 9593667
VCP NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RBPJ NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16763620 12700242
TCF7L2 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16849547 11935128
PPARD NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17620284 19587222
STAT3 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15950906
NR0B2 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20375098
YWHAG PROS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS15 XBP1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
YWHAB RPS6KA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216182 12618428
STAT3 SLC2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19006119 15194489
TCF7L2 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18602747
STAT3 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19088723 14712222
YWHAG VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
NCOA3 RXRA â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CBP SRC â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22364282 15615775 16713569 16860316
CFTR YWHAG â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
CFTR YWHAB â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CREBBP RXRA â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CDH1 SRC â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
LRP6 WNT1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
CBP FOXM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27542221 15024056 28387346
HNF1A DYR1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 14500717 11980910
PHS PHS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 20211142
PHS2 HNF1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 35140242
ACTB EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 33742100
ESR1 BCOR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 26487511
CBX3 BCOR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
CIC CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29844126 34079125
CIC GATA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29844126 35140242
CIC NFIC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29844126 35140242
FOS ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
KAT2B NCOA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 9346901 9445475 9267036
NCOA1 NCOA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17476305 18267973
NCOA3 NCOA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11971985 18267973
NCOA1 PPARD â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CTNNB1 PITX2 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
KDM2B FOS â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 26725323
CFTR HSPA4 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
AXIN2 CTNNB1 â—¼   DOWN_REGULATES ✅ - 0.83 0.83 Signor 11940574
ESR1 NCOA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 0.83 0.83 Signor 11477071
NCOA1 NCOA2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
NLK TCF7L2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
APOA1 APOB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19164805 7592581 28183703
DYR1B CBP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23602568 32707033
DYR1B EP300 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23602568 32707033
BCOR HDAC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23658227 16713569 10898795
ESR1 FOXA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23403292 25303530 28336670 27926873
ESR1 RXRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9121466 23403292 9717844
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
HDAC1 NR0B2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ATM ANXA2 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
HDAC1 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ACE2 AGT â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
APOA1 APOA2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10722751 3104518 24981860
CFTR LDHA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
XBP1 FOS â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 1903538 16189514
HDAC1 SAP130 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
WNT1 LRP6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11448771 11029007
CBP NCOA2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15657427 9192892 15987788 11971985 9430642
CBP GATA3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29453984 35140242
CBP STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11239394 15653507 15649887
DYR1B PHS â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11980910 16189514
CBX3 ZMYM4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27705803 34079125
ESR1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
HDAC1 PPARD â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11867749 18037904 16189514
SRC RXRA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17363140 10517671 15116119 15140878
NFKBIA RPS6KA1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
EP300 RUNX2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
PHS HNF1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 35140242 32296183 20211142 27684187
ESR1 ACTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20308691 19805454 21182205 21182203 31527615 20348541
SRC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
NR5A2 NCOA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15604093 22504882 23975195
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BCOR KDM2B â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
YWHAE YWHAG â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CDX2 CBP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19117933 10066780
EP300 CBP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 30110629 9267036 15598887 31753913 17970752 25314079 10899165
CBP HNF1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10777539 15598887
PROX1 NR5A2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15205472 16488887
NR0B2 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11861507 9773978
ESR1 GATA3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
MAFA PDX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15664999 15665000
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ESR1 HSPA4 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
NFKBIA VCP â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CREBBP KAT2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
BCL6 BCOR â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MAPK1 STAT3 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
APOA1 ABCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12084722 27017521 30458687
HNF1A PHS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 35140242 11980910 17353931
HDAC1 BCL6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16147992 10611298 9627120 9753732 15454082
POGZ CBX3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 34079125 20562864 27705803 21888893 20850016
KAT2B EP300 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12888487 22384255 9267036 12419806 21413932 20870727 33051058 8684459
RUNX2 FOS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11274169 11641401
NCOA1 FOS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18511550 10847592 9642216
GATA3 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34026424 29453984 26028330 31409898
HNF1B HNF1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10484768 35140242 33961781 2044952
KAT2B NCOA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9223281 9445475 9296499
NCOA1 STAT3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11773079 17471507 16713569
NR0B2 RXRA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12198243 21988832 16189514 10594021
PPARD RXRA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15888456 34081964 19756148 22205725 15604093
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
EP300 NCOA3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
KDM6A KMT2C â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
NCOA1 CBP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9445475 9192892 11003650 11113179 12482968 15615775 8616895 12163591 11971985 16713569 16860316 14722092
KAT2B CBP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9445475 11864601 9710619 9267036 9687513 8684459 9687573
CBP FOS â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11782371 35140242 16055710 10487758
CBP ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18765668 14766010 11113179 17400812 8616895 9192902 11782371 23403292 16417649 27420286
PROX1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15205472 16488887 23626788
HNF1A PHS â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 17353931 21988832 21047120 9092652
HNF1A ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16670373 20576918 17210751
GATA3 ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19559773
FOXM1 ALDOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 1956774 8383844 7843280
CEBPA APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9921275 1545795 8344962
HNF1A APOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15933209 1545795
CEBPA APOC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2161843
NR2F1 APOC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7640286 1639815
NR0B2 APOC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15637110 22197810 20516075
HNF1A APOH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17854747 14984368
CDX2 AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23393221 24501326
BCOR BCL6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23911289 33468080 20807888 26496610 18280243 16713569 15004558 10898795
MAPK3 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9649500
EP300 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17828269 12402037
BCOR HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 10898795
HNF1A CDH17 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20568120
CDX2 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16002547 7698771 12783165
CDX2 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22671145 19782160
HNF1A CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19074951
FOXA2 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19074951
FOXA1 CEBPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19074951
CEBPA SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14712233
MAPK1 CIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21087211
NCOA2 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14966289 11747826 16613851
CREBBP HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10777539
CREBBP STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15649887 11773079
STAT3 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20830236
CTNNB1 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16575901 16043491 24692107
ESR1 CYP2B6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20079471 18414489 22484313
ESR1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15358113 15499176 18299335
HNF1A DPP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10733933 16781669 9931303
EP300 HNF1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 15598887 11978637
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EP300 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20851880 22298955 12697832
NCOA3 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18484708 20181721 19491275 10490106 25728767 26166704 12554772 18645020 16923966 16331275 16713569 11376110 21182203 23403292 11050174 9192892 26487511 28844863 11353774 15145444 17158759 11389589 14966289 9346901 26153859 17646391 20392877 15383283 12630920 9765300 12714702 14766010 30418174
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9259327 10409727 23874500 11014206 15604093 12554772 16282588 9427757 11113179 18451880 9121466 10598586 16713569 11165056 14715875 11376110 9774463 10760302 20608937 9192892 11003650 26487511 11867769 10454579 12574227 17363140 9773983 10731636 11358671 11250900 11682626 23975195 17627277 16606617 12630920 12714702 9192902 12738788 16957778 15140878
SRC ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17043237 17284441 17400812 15604093 11032808 17921256 18451880 15020686 12736255 11564893 23065768 10454579 20935677 17363140 16957778 14963108 11013076 29720121 15784253 24498420 17627277 12630920 22328528 14766010 24051437 7539106 27420286 15140878
FOXA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21572391 20501593 24290378
RUNX2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17350616
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
PROC F8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 1939075 1761551 16189514
RXRA FABP5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23991366 22871568 20042001
FABP5 PPARD â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23991366 22871568 20042001
NR0B2 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19509248 12571228 9452499
FOXA1 UGT2B15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20736324
FOXA2 IAPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24627476 15566941 11875061
FOXM1 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15358835 7532283 8817653
HNF1A GJB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12850269 12413486 10760574
NR2F2 HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10331424 8622679 9111350
RXRA HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11027556
HNF1A SLCO1B3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16741617
HNF1A SLCO1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11483603 12601360 17932728
HNF1A PDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278466 11590182
HNF1A SLC10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12547402 14701722 20576918
HNF1A PKLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8314745 2246264 16204235
HNF1A SERPING1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12184632
HNF1A SLC5A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19722712 20600102 18656622
HNF1A PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14585510 7935427 9039828
HNF1A MTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18697801
KAT2B HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10777539
HNF1B PKHD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15067314 16221171 15647252
IFNG STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10707961 11960596 28264935
NCOA1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12163591 10809234 10777539
MAPK1 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK1 PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16231973 12459785 23109003
MAPK3 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK3 PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16231973 12459785 23109003
STAT3 MUC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18573283 15485908
NR1I2 NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15331348 16455805 12072427 17429319 19171678 18096694 23602807 23160820 15604093 12909012
NCOA1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 17400812 17495236
NCOA3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 12650696 17671194
NR1I2 NFIC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
RXRA NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23546875 19111018 15202934
NR0B2 SLC10A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12456679 15591588 15239098
NR0B2 SLC10A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11438503 14701722 16123152
NR0B2 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20185821 20375098 21081708
NR1I2 SLCO1B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11901222 12490595 12695338
NR2F2 NR2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 10900149
POU2F1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12650610 11126367
POU2F1 UGT2B7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10779377
PPARD YWHAE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17303761 18678619 17409426
PROS1 PROC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 1615482 2461936
PTPN6 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18508557 15870198 10545526
RPS6KA1 VCP â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
CREBBP CTNNB1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
KDM6A KMT2D â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
KDM6A PAXIP1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
AES HMGB1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 11748221 16713569
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
CTNNB1 NR5A2 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
ESR1 NCOA3 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
NCOA2 NR5A2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
HNF1A PCBD1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ESR1 NR2F2 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
NCOA3 CBP â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21914189 9445475 17043108 9192892 11823864 33589584 16227615 8616895 9267036 15383283 26267537 11971985 11076796 16713569 9346901 21632823
ESR1 NR2F1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
AXIN2 CTNNB1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
TCF7L2 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 11713475 5214798
NCOA2 ESR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12837248 17697320 11014206 12554772 18499756 15657427 11265755 9430642 11376110 9774463 16645043 9192892 11937504 26487511 12612084 19460354 20348541 11250900 12630920 12714702 14766010
NR5A2 NR0B2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 20516075 21262773 14963109 12198243 11668176 20375098 22504882 21566081
CREBBP NCOA1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ACE2 SLC6A19 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
NR0B2 NR5A2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
NR1I2 RXRA â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CREBBP NCOA3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
MAPK1 RPS6KA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
NCOA1 NR1I2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
NCOA2 RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ESR1 NCOA2 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
NCOA1 RXRA â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
ATM SLC4A2 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
CTNNB1 TCF7L2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PITX2 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8175747 1321332 7896852 10866832
FOXA2 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7961760 23293065 21653803 12107072
CEBPA APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15109267 1900840
ESR1 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11013347 18005483 9535920 17532863 23293065
APOA1 ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 30458687 12084722 12869555 22271762 27100352
NR0B2 G6PC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15358835 20688914 18505831 21081708 18459945 17909097 19720831
HNF1A G6PC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11864989 12760745 15933209 9839806 11544200 10766845
HNF1A SI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9806892 12060663 17466947 11408257 8006012
CDX2 SI â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10889158 11283019 18005670 12060663 16480684 17466947 11408257 16574312 9679043 20133952
NR1I2 ABCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21733184 24498169 11836020 11706036
AGT ACE2 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 15283675 10969042 10924499 11815627
ACE2 AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10969042 11815627
CEBPA AFP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17188819 7549116 7518671 1377818 15924879
HNF1A AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20978123 17475670 1515023
HNF1A AKR1C4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11284743 12220531 2044952
HNF4G AKR1C4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11284743 12220531 2044952
CEBPA ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8314088 8703043 16608438 10198916 16452305 19932685 8288579 7564318 10542249
DBP ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1588973 1922023 8617210 2958390
HNF1A ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 8443410 12760745 8262148 11939905 2736625 8288579 1321810 1487491 10542313 14561216 22196858 8102976 1942067 15598887 7519016 1685988 8626635
HNF1A ALDOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8165139 15933209 1956774 8383844 12034748 7843280
SRC ANXA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 30081903 15302870 24239898 23594883 18083107 2415974 26716413 17389395 27821486 11106497 88296872 16189514 25574848 25303710 2456953 24727000 17287340 2143014 15212693
ATM PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
PAXIP1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15456759 19414588 17690115
ATM HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24821553 11980910
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
CTNNB1 AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24447505 15473860 11809809 22615875 11809808 12711682 11940574
TCF7L2 AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15473860 11809809 24447505 11809808 12711682 11940574
CTNNB1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10966653 19751508 7542250 8666229 17143292 11955436 11967263 23343194 22270359 9554852 22699938 16039586 16940750 9566905 19619488 15766563 12051714
HDAC1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
BCL6 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12097386 19631565 21518797 22585398
MAPK1 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9649500
CD3E PTPN6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
CDH1 TNF â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
CDH1 IFNG â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
HDAC1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20580679 19182791 21685935 21184735 24424621 18794357
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
CDH1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17496910 19029934 22370635 16099633 23343194 19734908 10744074 16039586 22203675 19171760 22007144 19619488 17143292
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
CDX2 CDH17 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15732140 20568120 16616718 12404231
POU2F1 CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21051540 20637099 11278400 20876643 16278805
CDX2 UGT1A8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15364550 15044625
CEBPA CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15100175 12695546 12542705 15778453
CEBPA PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10854692 9867832 8093246 7935427 10681569 10224054 17094771 12560325 12237288
MAPK3 CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 20101026 14701740 26515730
MAPK1 CEBPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14701740
MAPK3 CIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21087211
RPS6KA1 CIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21087211 33103082
CTNNB1 CREBBP â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
CREBBP TCF7L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
NCOA3 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10777539 14966289 22977234 15798179 22608253 11747826
NCOA1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10777539 15671023 12748280 11463834 14966289 19194461 9792627 18193094 11747826 17400812 17244199 9223281 10594042
NCOA2 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 15657427 15987788 9192892 9430642
KAT2B CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9687573 8684459 9687513 9445475 11864601 9267036 17496784
CREBBP NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 15657427 15987788 9192892 9430642
CREBBP CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10769018 21751375 11973335 17410209 18347063 16476742 23273993
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
STAT3 CRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9566874 12667216 18684932 8621622 20978825 16116232 10880233 18292576 23361365
HNF1A CRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21176092 8703909 19280766 18292576
CSNK1A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 64.0 1.0 Omnipath 9312064 29495399 14966280 23531534 21764279 26227550 29793495 28220106 20561505 26862734 19293931 19623618 27558955 28430641 11818547 25546293 16199882 24648413 28337019 27672271 11955436 9482734 25915038 20419129 23778311 19244247 25500543 27768599 27488834 28183999 17208333 24594309 24038789 23076981 24904820 23690993 23744610 12000790 23687614 12114015 10488109 26604501 19711366 20699366 25517963 26189775 10023673 22025562
CSNK1A1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 14613942 19651622 17081983 15119949 18691976 20068231 18452278 9360956 16045749 12062430 18077418 19415658
CSNK1A1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 25301071 23331499 21887268 16890161 27821587 14731402 24794231 25735981 20229235 16341017
TCF7L2 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24214913 14706452 19347947 24317174
RXRA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12771132 25241761
WNT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 21108734 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 16554443 18936100 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 15208637 21796133
LRP6 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 25088803 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
FZD1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
CTNNB1 HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12107263 11266540 23331499 15055546 16442529
CTNNB1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17145710 9488439 11713475 12446687 17143293 27902311 16569639 22014570 16724116 11955446 16442529 26350900 19202075 17050667 20126258 22056988 16306047 17914096 19443654 18391971 21670201 22155184 10080941 17283121 16230076 22304967 16630820 15684397 11713476 12861022 19304756 20492721 19816403 18772112
CTNNB1 PITX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 25241761 21071413 19174163 12464179 15728254
NCOA1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17429319 18299335 23179081 19077665 16455805
NR1I2 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 18805405 17526937 15499176 18299335 20538721 15367577 18096673 12542705 15269186 10935643 18784074 11329060 12417264 16013442 11602528 19171678 16455805 19077665 19934400 23732298 23807564 23928187 23891548 21920351 17293382 11991950 9727070 15180306 15698577 17764444 21292004 11602521 11336976 12781341 12606758 10403778 12167569 19712670 12664659 22982774 21311750 20736322 16219912 21342487 21733184 19129222 19138736 19232333 23179081 22976785 19686701 15650019 11581012 23536728 12130689 12601364 15523048 16608838 17035600 12072427 17429319 10570062 18332045 12851153 10772626 11114890 20171174 15100175 12514743 10611146 20942813 19074998 18540626
RXRA CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19712670 18400206 16608838
HNF1A CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14742674
HNF1A CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15933209 10403849
NR0B2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 19346330 15314177 23038264 21566081 18323469 19805516 11030332 20375098 15358835 15817812 21817852 12525500 21963511 17145766 17654698 19085950 19056864 16049268 15581596 11518759
NR2F2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10627496 9092518 10403849 9799805 23458092
NR1I2 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15629111 15322103 15331348
RXRA CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19106115 20338915 16049268
FOXM1 CYP7A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9013589 15933209 9799805
NR1I2 DBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19129222
HNF1B DPP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9931303 16781669
DYRK1B HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14500717 11980910
IFNG EP300 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
EP300 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15731352 20448036 10490106 9920895
NR5A2 ESR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
ESR1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18234909 11522780 9869301 10428965 12761896
ESR1 UGT1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10854430 23714156 9773976 12114525
ESR1 S100G â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18313836 15456916 15062543 15329476 15635152
ESR1 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23911789 19376833 16091743
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
ESR1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20616010 20068169 16950141 21029304 19433249
RPS6KA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10949034 15528270 19925796 15461668 25336146 11139588 12118371 30034315 15059947 16076840 7491495 12093745 11432835 10411321 11507039 9528769 7838153
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
KMT2D ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 16603732
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
NR0B2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 21071413 9773978 18988627 11861507
ESR1 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18499756 9192892 9430642 11014206 19460354 15657427 23331499 11477071 26487511 16645043 12612084 20348541 12630920 14766010 17697320 11937504 12714702 12554772 9774463
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
ESR1 XBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12954762 12047351 14605097
FGFR4 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR4 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR4 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 19901323 10918587 9305919 8272872 12626508 16497976 15592455 17389395 12576423 11350938 11294897 12244095 9083098 8626374 9566874 11940572 11429593 14551213 11850821 17016520 9582023
STAT3 FOS â—¼   UP_REGULATES ✅ + 38.0 1.0 ACSN 10347215 11528470 12223527 13130303 14607900 14670306 15218058 15356132 15573129 15810077 16418395 16716598 16831886 17403902 18297062 18776941 18832382 19380816 19412634 20093776 20237412 20406969 20581311 21317430 21840487 21883379 22006115 22943793 22945800 23124025 23454751 23953057 24857661 27216177 28186502 7543512 7768934 9278421
STAT3 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17204573 14737107 12640143 12600988 11685114 8071311 15040450 16293640
FOS TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19285436 2506186 16834785 22322974 10837498 12057991 9030359 25567680 19026727
FOS IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19285436 16713974 7759501 8756632 12842891 12432566
FOS NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14686613 7679081 8603591 9776360 14565925 12788789
RPS6KA1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15187187 21233202 9920881 23331499 7601337 16286006 20068231 18452278 18988627 16393692 8248197 1545828 15239952 16055710
MAPK1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 12134156 20506250 15547943 8248197 7816602 15084594 12697810 8226933 20068231 18452278 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 21098038 9604935 11274345
MAPK3 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 17018293 12134156 20506250 15547943 7816602 15084594 12697810 8226933 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 26725323 21098038 9604935 11274345
NCOA1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18511550 10847592 9642216
GATA3 FOXA1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
FOXA1 HDAC1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
FOXA1 UGT2B17 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20736324 20628005
FOXA2 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17471492 15790780 18847435 15123725
FOXA2 SLC2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24157454 19433262 12509444 10748140 16055718 11875061
FOXA2 PDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12052878 12970316 10652343 17510498 21385937 19141476 11278466 11875061
FOXM1 PROC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15933209 7592627 8945631
FOXM1 SLC2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11915024 15933209 10748140
WNT1 FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 10862746 20006983 17433286 23396967 15143170 15169958 21316585 16495441 20940229 23140633
LRP6 FZD1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 11448771 11029007 15459103 12205098 22000856 22653731 11357136 15084453 23256519 23791946
WNT1 FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10557084 22944199 15578921 16936075 24032637
GATA3 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17717199 20399120 11970994 21507199 20193034 23232398 20636338 21632975 8228802 19648923 15251440 16520391
PDX1 GCK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8866550 24157940 12426319 11825903 9453241
HDAC1 TCF7L2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 TNF â—¼   DOWN_REGULATES ✅ - 15.0 1.0 ACSN 10754326 10952726 11875494 12907458 14660645 14668329 15465827 15644117 16878026 17404308 17485448 21234400 22796940 23390297 7594497
IFNG HMGB1 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
TNF HMGB1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10925299 11112697 11438547 11875494 12646658 12811837 1431106 14607933 14625680 15099563 15699106 16713974 17916596 18633355 19411070 20038811 20184663 20435894 21133840 21411734 21826665 22595692 22955274 23170255 23430059 23508573 23510023 23567181 23769623 24092389 24378531 26201938 8910423
HNF1B HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15486044 1363228 16793932 15001636
HNF1A UGT1A8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15364550 15044625
HNF1A UGT1A6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12946651 16399343 11544200 15933209
HNF1A UGT1A9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17264800 15044625
HNF1A PROC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15933209 8945631 11140943 9553065 7881411
HNF1A IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7683517 7678342 7692852 9369450 7684229
HNF1A UGT2B7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16788384 9052741 10779377
HNF1A INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12712243 1142872 15933209 10491332 17210751 9822613 11994285 14521933 18949455 11428722 1380153 10331424 17116178
HNF1A SLC22A10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20829431
HNF1A SERPINA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 2844524 10330009 2020548 3263567 3262058
HNF1A UGT1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16399341 19541828 20096102 18172616 10462540 9052741
HNF1A UGT2B17 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11191885 12065766
HNF1A SLC2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12712243 11978637 15933209 19336222 10748140 24157454
HNF1A MIA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12586826 17881540
HNF1A MTTP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15337761 22357705 18697801
HNF1A PAH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15933209 11762195 20943816
NLK HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14960582 18855897 11274345 20194509
PCBD1 HNF1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24204001 1465414 20211142 18418350 32296183 8444860
STAT3 IFNG â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 10347215 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 19380816 20093776 20237412 20406969 20581311 21115385 21840487 23124025 23454751 23953057 24857661 27216177 28186502 7543512
PTPN6 IFNG â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26667266 26755705 27474009 8976179 8986721 9751747 9765283
STAT3 IL17A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22665476 24412612 17363300 16698929 20493732 21949021 21151104 19265112
STAT3 IL17F â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26750311 24412612 16698929 20493732
MAFA INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 51.0 1.0 Omnipath 15664999 9604866 19785038 21063109 17449132 17149590 19502415 24258027 15944145 15650027 21565207 22172402 19576197 15923615 14765989 18506085 15993959 14680841 17927952 17259388 12368292 23775071 17583797 16780794 19264802 22968147 23382704 23737644 15664997 15862113 16505238 23927931 19029092 22466807 17569705 17785922 15665000 16461554 21278380 22974359 12917329 14973194 18515495 8584024 21830322 8289826 17300753 17360442 9414097 24472553 19689288
ISL1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14664703 8833653 23129807 19502415 7759514 19619559 12716747
PDX1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 134.0 1.0 Omnipath 10636926 10567373 19275670 15664999 10748090 10393088 10440129 15944145 17312465 9453241 23796517 15180990 12150938 16148004 12426319 12099699 9199333 17991720 22968147 23737644 11423476 23153982 7575438 17512083 15743769 10331405 16461554 22974359 17299038 18951876 24472553 16901969 9604866 10720084 20943817 18252719 15001545 7491105 12684063 22172402 8986763 20886630 22028710 15993959 11309388 11428722 10924326 16675598 15862113 12783165 10385428 11316746 9252422 16141209 16887799 10629047 15885879 8988180 20007976 10868963 10545531 22150363 9873045 20531294 16055439 18274620 11477691 9649577 12606496 11834725 10545530 12665509 15166251 8697303 23853095 12475772 20339896 7568086 21393239 17150967 16280646 17259388 19264802 10485916 15664997 8922372 23927931 22570331 21540283 22167125 10426567 21335550 21278380 11003654 17299998 23703573 8483904 15496408 18360684 21063109 17449132 7708065 22253604 10585868 16543365 10905482 1944296 11181516 7937976 21076579 18772243 8954967 17927952 7901001 23434589 23382704 14550306 15790780 9637677 10672004 11457885 12193567 17569705 12130581 17785922 20811152 17627512 17706592 8799146 17991758 11549279 19689288 9230347
NKX6-1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19264802 22968147 10799563 18506085 11309388 16101311 23382448 10567713 21983268 9230347
PAX4 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10567552 17299998 10601637 21263211 11263967 10891400 17426099
MAPK3 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17496910 18039929 19541618 21965663 20974802 19565474 15547943 12063245 12738796 11226259
WNT1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21078818 11029007 10557084 23331499 29444668 21071413 11448771 18988627
MAPK1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17496910 18039929 19541618 21965663 20974802 19565474 15547943 12063245 12738796 11226259
PDX1 MAFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21081123 15664999 9604866 17510498 17259388 16461554
MAPK1 MAFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18535013 29339498 23660596 11416124
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17081983 32814053 20385094 11532940 7601337 23331499 15342917 8939914 21071413 23047924 20068231 11335727 9687510 12618428 18988627 18669648 23519423 23109003 18691976 12594221 9915826 17906627 8202512 9430688 19651622 12832467 11500364 14966081 29997244 25730857 8387505 10411321 18212344
MAPK1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10377179 17604322 12048211
MAPK1 NCOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10660621 12163482 11073973 20068231
MAPK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 59.0 1.0 Omnipath 18448488 19413330 11335711 9343414 15465816 25584415 12576423 11350938 20068231 12681450 12763138 9872331 11780390 18491316 18669648 11404481 10521505 18691976 20058876 15979846 14551213 10446219
MAPK3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 27687725 19264160 29057206 25867060 19801668 25122769 21965325 25187572
MAPK3 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17804409
MAPK3 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 15342917 18039929 12832467 23109003 8387505 14966081 9915826 21071413 17906627 9430688 11335727 18988627 11532940 10411321
MAPK3 NCOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12163482 11073973
MAPK3 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 10383391 12048211 10377179 15688020 18003614 27852823 17604322 11606411 20432439 16551633 12824162 15212693 17900311
MAPK3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 18448488 19413330 11335711 9343414 23331499 15465816 25584415 12576423 11350938 20068231 12681450 10417333 12763138 9872331 18988627 11780390 18491316 18669648 11404481 10521505 18691976 19723038 20058876 14551213 10446219
MAPK8 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 23255093 17502367 21702955 19413330 11335711 9343414 23331499 15465816 12576423 11350938 20068231 12763138 9872331 18491316 18669648 10521505 18691976 20058876 15979846 14551213 10446219
MAPK8 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 7890696 15696159 15071501
MAPK8 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16551633 10383391 10938283 16038797
MAPK8 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 29578371 17081983 19007248 23434668 21540183 22622703 17924679 18187866 24296261 18838864 19413330 20027304 21471201 19107194 16964243 18669648 15302935
MAPK8 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 18985696 25862939 15696159 11956222 19788416 21081103 15071501 18559254 7890696
NCOA2 NCOA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
NCOA1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11773079 16713569 15313931
RXRA NCOA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
NCOA2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 12612084 11981034 15657427 23331499 21071413 9430642 10748178 11514567 18988627 11851396 17947383
NR5A2 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
NFIC PROC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9174162 15933209 8945631
SIRT1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19408108 15152190
SRC NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 24216290 12432072 24637265 12429743 25671697 14991073 8797825 24101387 9792645
TNF NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19053972 24083678 25215581 29088783 24386331 25888769 20460401 16866128 19934328 9363938 24349153
PDX1 NKX6-1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11309388 16297379 23382704
NLK TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 16714285 14960582 12556497 12901858 11274345 20194509 18855897
NLK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17563747 17145710 15764709 15004007
POU2F1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19467240 22349263 14630716 11134960 24459328
SRC NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20015194 19875457 16116474
NR5A2 NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20375098 11705994 10409629 24498423 14627819 17204240 11518759 20460755
NR0B2 PCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15358835 20688914 18505831 18459945 19720831 17094771 22977252 12324453
NR0B2 PTPN6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 21719561 11834522 12071971 18519703 9452499 15870198 17218319 9029091 22458980 11679424 11021818
NR0B2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 23331499 16189514 12198243 10594021
NR0B2 NR1I2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12805410 23331499 16455805
NR0B2 NR5A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 14963109 21262773 11030331 15723037 20516075 21566081 22504882 12198243 11668176 20375098
NR1I2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 9727070 15604093 11706036 9489701 16189514 26855179 23160820 22976785
NR2F1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1311101 23331499 10900149
NR2F2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 7479078 8119938 10900149
PDX1 SLC2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19651901 22403172 23153982 9637677 17149590 11309388 8923459 9453241
RXRA PPARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 22205725 23331499 15604093 9933587 19756148 11237216 15888456
PTPN6 STAT3 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 12176909 12773515 12917349 15240681 15713798 22513334 22952938 25355530 26667266 27474009 8976179 8986721 9765283
SRC PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 8692915 17675340 14551136 25535246 14699166 12468540 10574931 16649996 8647855 7512963 9261115 34010642 14757045 12468645 8114715 15212693 10488096 21900501
RUNX2 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18410224 19903460 20713445 14506237 19259985 19915614 21455926 23644099 9794229 11331591 16670084 16195230 19649655
SRC RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10322133 23331499 15140878
SRC STAT3 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 16472776 17192274 19930715 22131018 22677902 23589069 23691193 24030100 24403062 25687758 27036022 27452906 29556339
SRC UGT2B7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19289110 21056984
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
TCF7L2 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22552774 12750294 26947016
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAG YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
ATM VIM â—¼   KO_DOWN_REGULATES ✅ - -2.44 2.43 PKG 28854368
ATM SPP1 â—¼   KO_DOWN_REGULATES ✅ - -3.83 3.82 PKG 28854368