Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FOS VEGFD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23157741 19136250
NR3C1 VEGFD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18199540
RAC3 RXRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0705356104 17947383
NCOA3 RAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19305643 24918060
PAX8 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8521821
PAX8 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9413150 11453662
CAD TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RRP8 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3C2 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3C2 SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
EGFR H3C2 â—¼   COLOCALIZATION 2.0 0.8 intact 5216105 12577067
H3C2 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
NCOA2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
KAT6A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
NCOA3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
CREBBP H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
NCOA1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
SIRT1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19270680
RRP8 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H4C6 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16628214 5218530
H4C6 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
H4C6 SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H4C6 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
H4C6 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H4C6 ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19146767 11673449
H4C6 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18079182 11448779
H4C6 SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
H4C6 KAT2B â—¼   ACETYLATION ✅ 2.0 0.8 Reactome 23667505 23555303
NCOA2 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
NCOA1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
NCOA3 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
KAT2B H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9880483
NR5A2 ADIPOQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12829629 16803864
PPARA ADIPOQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12829629 17194889
CTNNB1 AHR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19651607 0902132106
AR AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 23689136
AHR NR1I3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17627975 18978342
AHR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114727 16091746
AHR PDLIM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19279104 17963943
AHR AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19815066 17392787
PKN1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1218925110 23223530
PRKACA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
NR4A1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11274386 16835233
NCOA3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 20305690
SIRT1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21775285
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
AKT1 SP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21619873 21777568
TP53 ANKRD11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18840648
ERG AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8388477 22531786
CCND1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16461912 0506281103
NCOA2 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
AR SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1384159 20610535
AR POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18703637 15375188
AR CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24218937 20610535
AR ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11371645 20610535
AR MEF2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23598283 20610535
AR CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16492776 16344550
AR DNM1L â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10454563 21724752
AR RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12069693 20610535
AR TFF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18516291 21170267
AR VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15805579 16425262
RXRA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
AR RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
ARNT ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17991765
ARNT IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20511231 21104991
ARNT TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15627257 23359428
CREBBP ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12573436
RORC ARNTL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24737872
PPARG ARNTL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19041764
BRCA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TP53 ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9925639 10435622
ATR BRCA1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 23422745
NCOA3 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22213475
BCL2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15210690
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
BRCA1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15574597
UBE2I CARM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NCOA1 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14966289 15988012
NR1H4 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15471871 16819395
PPARA CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20146263 15314095
ESR2 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138116 16423895
PPARG CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21690289 12813462
SOX17 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21957254 19479035
KLF8 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21518760 12820964
NCOA2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21505052 22581837
NCOA1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21163886 22542550
EGFR CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7945309
EP300 CCNT1 â—¼   ACETYLATION ✅ 2.0 0.8 intact 7265510 19387490
CHUK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12799363 23430059
TNF CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21887257 19287455
FOS COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10639331 10914841
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
STAT6 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15145939 10373589
CREBBP VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10406465
NCOA2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
CTNNB1 SOX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17218525 17875931
MEF2C CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24473123 18758483
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
SOX17 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19301122 21957254
CTNNB1 PPARD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11943708 17724465
RARA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10607566 23331499
VDR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11470825 23331499
SIRT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27776347 28583374
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
VDR CYP3A4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11991950
KLF15 DR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC DR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR1I3 DR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17464991 16492670
MYC EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18365874 11509655
PML EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12673202 9819401
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RARA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11788593
EGFR PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499
STAT6 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8415882 23461825
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21988832 20089040
SLA ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
HNF4A ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17914096 10915780
ERBB2 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19861462
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
PSMB9 ESR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219051 16957778
THRA ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11578528 11687272
NR1I3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15268900 21389059
ESR1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19797124 20819530
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
ESR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16144913
ESR1 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15217907
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
HNF1A ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11522780
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16144913
ESR1 TFF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 6593703
ESR2 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15217907
RARA ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9841885
ESR2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9841885
PPARG ESRRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20519122 15821111
ETV4 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7896795
NR1I3 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF15 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
RARA FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19546303 9507016
PPARA FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17360982 18754816
STAT6 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18342537 11922943
UBE2I FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16055711 16236267
SRC FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17160021 22105363
NR2F1 HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8622679 9111350
NR5A2 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12069850 10799577
RARA HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11585914
HNF4A TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20621834 16771709
IKBKB TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19196987 0812256106
UBE2I IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14651848 16906147
TBK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
USO1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC IKBKG â—¼   COLOCALIZATION 2.0 0.8 intact 20970423 8045055
NCOA1 KANK2 â—¼   COLOCALIZATION 2.0 0.8 intact 17476305 5219902
KLF15 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NR3C1 KLF15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20956975 23508109
PPARG KLF15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20592862
NR3C1 KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27777311
KLF5 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16102021 10865841
KLK2 SERPINE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10209959
PGR KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9052414
PPARD LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10634806
MEF2C NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18079734
MSH6 PSMD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
NCOA3 MSH6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14966289 11747826
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
MYC TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15466196 12080469
NCOA3 NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17476305 5219902
PSMB9 NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219051 16957778
RXRA NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17673910 5223765
NCOA1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16186500 14551261
NCOA1 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16423881 15688032
NCOA2 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12970370 19321449
NCOA2 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19305643 10454563
NCOA2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19805480 16483936
NCOA2 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11923473 23936147
NCOA3 SRA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19305643 11358796
TP53 NCOA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
NKX2-1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PPARG NR1H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
PPARA NR1H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
PPARD NR1H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1H2 PPARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1H2 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1H2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1H4 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19028791 19864602
NR1H4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21279417 15973435
NR1H4 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11518759 11030331
NR1I2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
PPARA NR1I3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20208394 17962186
NR4A1 NR2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9130711
NR3C1 RXRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10860926 12573484
NR3C1 SFTPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17003084 18079322
RXRA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12573484 23331499
NR3C1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12573484 23331499
NR4A1 RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9343423 11979430
RARA NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10772826
NR5A2 UBE2I â—¼   SUMOYLATION ✅ 2.0 0.8 intact 17036045 5219211
PDLIM7 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 PDLIM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22266808 15829976
PGR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14500579 16175636
TP53 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
RXRG PPARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPARA PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PPARG RORC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9702045 19737866
THRB PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16260719
TNF PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22078880 20651683
PPARG PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18309368
RXRG RARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RXRB RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12767074 1310351
THRB RXRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220566 7746322
RXRG SFTPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9700083 10070102
SENP1 SUMO1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 22878415 8402547
TP53 SERPINE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
SOX10 SOX6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17084361
SOX6 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084391
TP53 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11420669 21187340
THRA THRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1782215 17761769
TP53 TNFSF14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11358973 8663350
TP53 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
NCOA3 RXRA â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CCNT1 MYC â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
ANDR KAT2B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11328859 10779504
CBP SRC â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22364282 15615775 16713569 16860316
CREBBP RXRA â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
NCOA2 RORC â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ARNTL CREBBP â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
SLAP1 NCOA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SUMO1 ANDR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12177000 21242980
KLF15 CBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 35016035
CBP KLF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
SNW1 CCNT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19818711 20467437
MYC CPSF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
EGFR PSMD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
ERG EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 28536097
EP300 KLF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
FLII ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 14966289 19720835
FOS ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
ESR1 MSH6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
ESR1 SNW1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 19934264
ESR2 PSMD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 29509190
KAT2B KLF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
KAT2B NCOA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 9346901 9445475 9267036
RARA KLF5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16224062 18466769 21383775 16102021 12101409
MYC PSMD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
NCOA1 NCOA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17476305 18267973
NCOA3 NCOA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11971985 18267973
PML PPARG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20211142 32929351
PPARA RXRG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16169070 22205725
PPARD RXRB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15604093 22205725
PPARD RXRG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15604093 22205725
PPARG RARA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 32929351
RXRG RXRA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOX2 UBR5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30894683 23667531
SOX2 SUMO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25416956 17097055
NCOA2 NR5A1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST4H4 SOX2 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
NCOA1 PPARD â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CCND3 CBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MAGAA KAT2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MAGAA NCOA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 26496610
MAGAA PKN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BRCA1 CDK9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22990118 28278048
SNW1 CDK9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26209609 19818711 20467437
ESR2 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18765668 11500849
KLF15 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 23999430 35016035
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
NR1H4 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25675114 17333335
NR1I3 MED23 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SNW1 MYC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30415952 29467282 19818711
NR1I3 NCOA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HNF4A NCOA2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HNF4A NCOA1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
AKT1 BRCA1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EID1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BRPF1 HIST3H3 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CREBBP NCOA6 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ESR1 NCOA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 0.83 0.83 Signor 11477071
IKBKB SRC â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
NCOA1 NCOA2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
NCOA2 NR1H4 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CTNNB1 PPARG â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
AR SRC â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CDK9 TP53 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SNW1 UBR5 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ANDR ERG â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20478527 22722839
EID1 CBP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15987788 24167073
MAGAB NCOA2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20448036 19828458
AR CCND1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
BRCA1 NCOA3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14578343 16860316
ETV4 EP300 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14976201 35140242 9194565
ESR1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15961505 31527615
ESR1 RXRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9121466 23403292 9717844
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
PML FOS â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9671405 16189514
HNF4A NR1I2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15331348 16455805
NR1I2 RXRB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15604093 16189514 9727070 23536728
RARA RARB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 22022577
VDR RXRG â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15604093 32296183 20211142 15919723
CREBBP NR3C1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ESR2 NCOA2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PAX8 EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 35140242 10924503
ANDR EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28549433 34585037 23518348 10779504 18487222 23172223 27903893 16713569 24480624 32668201
AKT1 CBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19995607 23434580
NCOA2 ANM1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16713569 11050077
ANM1 NCOA3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16713569 11050077
ANM1 NCOA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16713569 11050077
AHR NCOA2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12024042 15641800
AKT1 ARNT â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28205554 28628118 15833858
NCOA1 ARNT â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12024042 10594042
MEF2C EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21556048 9001254
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
EP300 KLF5 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
HNF4A NCOA6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18552123 15604093 35140242 21292004
KAT2B NR4A1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12082103 16713569
NCOA6 NCOA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12482968 10567404 21292004
RARA NCOA2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12503607 9192892 12612084 20543827 9430642 16713569
NCOA3 NR4A1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12082103 16713569
SUMO1 PIAS3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24654937 15569683 16524884 19217413
PML RXRA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16540467 10610177
NCOA6 RARA â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CARM1 CREBBP â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CCND3 VDR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16105657 21988832
EGFR ANDR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12534934 15288768 15305378
CBP PIAS3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14691252 28680062
CBP NCOA2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15657427 9192892 15987788 11971985 9430642
NCOA1 AHR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12024042 15641800
RARA AKT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23693014 16417524
NCOA2 ARNT â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12024042 26350169
PPARG CAV1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12813462 21690289
KAT2B CCND1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10318892 11328859
ESR1 CCNT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 15940264
ESR1 DNM1L â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 19805454
ESR1 RARA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25604459 25303530 9717844
SNW1 RARA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19934264 9632709
RARA SUMO1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24819975 15171703
SRC RXRA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17363140 10517671 15116119 15140878
VDR SRC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12796488 21917910 16434701 12893883 15604093 20371703 15919723
CREBBP STAT6 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
NCOA1 RORC â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
NR1I3 RXRA â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CREBBP HIST4H4 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
CARM1 CBP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15731352 12374746 17043108 11701890
LIPA1 NCOA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11931740 16713569
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK4 BRCA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9244350 16713569 17334399 12509456
SRC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
NR5A2 NCOA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15604093 22504882 23975195
NR1I3 NCOA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 15572376 15604093 26186194 28514442
NR1H4 RXRB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26871637 32296183
RXRG NR4A1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12082103 16189514 16713569
SUMO1 SENP1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8402547 22878415
SUMO1 SENP1 â—¼   CLEAVAGE ✅ 0.87 0.87 mint 8402547 22878415
BRCA1 CREBBP â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AKT1 CHUK â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ATR TP53 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NCOA2 RXRG â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RXRA THRA â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PTGS2 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PML RARA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RARA RXRB â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
AR MAGEA11 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ATR BRCA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CDK9 MYC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CHUK CREBBP â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SUMO1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
NCOA6 RXRA â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EP300 PPARG â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ESR1 NCOA6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
RAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21217774 16331275
NCOA6 ANDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33640491 14645241
EP300 CBP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 30110629 9267036 15598887 31753913 17970752 25314079 10899165
CBP SUMO1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23395904 28630323 27129204
CBP HNF1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10777539 15598887
GCR EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17884810 23125313 12208951 31182584
AHR EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17392787 21988832 10999956
AKT1 NR4A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 16713569 11274386
BRCA1 NCOA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11085509 14578343 16860316
EP300 CCND1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10567390 15951563 11788592
MYC CDK9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17700062 12944920 30415952 26687678 19818711 11673469
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
EP300 VDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32603375 15647825 21988832 20089040
EP300 PPARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18797151 9407140 10336495
SRC ESR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11032808 12630920 15604093 11013076 12095943
ESR2 MED23 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11867769 21182203 29509190
HIST3H3 HIST4H4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
IKBKG TNFRSF1A â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
KAT2B RARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14581481 9445475 17475621
NCOA1 NR4A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12082103 16713569 16002533
NCOA6 NR1H2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15604093 11158331 12724417
NCOA6 PPARG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19596656 11877444 19047629 15604093 10788465 24368734
RXRB PPARG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20211142 22205725 25609649 15604093 30699358
RXRB RARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20211142 32296183 29892012 15604093 26871637 21988832 16713569 28514442 16189514 25303530
RARA RXRG â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RARA SRC â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10454579 12612084 17363140 17641689 20338915
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
IKBKG TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PML TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
BCL2 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CARM1 NCOA3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CHUK TNFRSF1A â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AR KLK3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CARM1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREBBP KAT2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
NCOA1 STAT6 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PPARA RXRA â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
NCOA3 PGR â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
SLAP1 EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 24658140 22973453 25402006 16273093
CAV1 ANDR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16713569 11278309
ANDR BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11085509 11016951 16713569
MYC CBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16878156 35140242 29467282 12776737
STAT6 CBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15695802 31554795 11574547 10454341
PPARG CBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17312272 15556564 35140242 19596656 17704298 22070604 30595551 10339548 16713569 10848596 11877444 10622252
KLF5 CBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18500350 35140242 16713569 12682370
CBP GCR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31182584 25511704 9649342 20018896 16713569 9590696
CBP BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10655477 9443979 9926942 12700228 16713569 16860316 11782371 16417649
ESR1 ANM1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23403292 31527615 11050077
EGFR GCR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
NCOA6 GCR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10866662 31182584 10567404 28611094
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
CCND1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9244350 16713569 17334399
BRCA1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26831064 18025037 20016594
NCOA3 CARM1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18511550 17043108 26267537 15383283 16938873 16923966
SRC CAV1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8632005 8910575 8621645 29720121
CCNT1 PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28555140 12727882
MYC CDK4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 21988832 28628118
EGFR FGR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
KAT2B EP300 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12888487 22384255 9267036 12419806 21413932 20870727 33051058 8684459
EP300 STAT6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23461825 17237818 10454341
EP300 NR4A1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12082103 21988832 16713569 20438716
NCOA6 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10866662 26487511 10681503 10567404 16794079 11773444
ESR1 MED23 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
NCOA1 ESR2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11500849 10809226 11014206 19126643 15604093 10731636 11376110 14715875 12554772
NCOA6 ESR2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15604093 11158331 11773444
NCOA1 FOS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18511550 10847592 9642216
HNF1B HNF1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10484768 35140242 33961781 2044952
KAT2B NCOA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9223281 9445475 9296499
MYC MSH6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17314511 29467282 17353931
MYC PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17146439 21150319 32592588 30415952 15735755
RARB NCOA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17363140 15604093 12665583 8754792
RARA NCOA6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10866662 11158331 16713569 10567404 10823961
NR4A1 PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12032831 16713569 16189514
RARA PML â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 1311253 10882117 11050004 16189514 16540467 20159610 12935927 16713569 10610177 18073335 17560333
PPARD RXRA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15888456 34081964 19756148 22205725 15604093
EP300 NCOA3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
IKBKG TNF â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NCOA1 THRB â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
NCOA3 RARA â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ESR2 NCOA3 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
NCOA1 THRA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
NCOA1 PGR â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
NR1H4 RXRA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
AR NCOA1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
IKBKB TNFRSF1A â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
NCOA2 VDR â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
NCOA3 VDR â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
ERBB2 SRC â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
RARA CCND3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16189514 12482873 16713569
NCOA1 ANDR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10567563 12163482 23975195 33640491 15256534 12612084 10731636 16713569 17353003
CBP ANDR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34585037 15691881 33640491 20541699 16713569 9822653 9482849 12810069
AKT1 ANDR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11156376 16210317 28708672 18332867 11404460
NCOA3 ANDR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16951154 10965917 14966121 21047772 33640491 11747336 15563469 16713569 32668201
ANDR CCND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16461912 10344732 15558026 16713569 11328859
ANDR MAGAB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15684378 18212060 21730049 23172223 24722188 19828458
ANDR SRC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15027889 15466214 24728074 11032808 15062576
HNF4A CBP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10882110 9434765 18552123 9792714 16713569 10085149
NCOA6 CBP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10866662 10567404 11158331 12482968
NCOA1 CBP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9445475 9192892 11003650 11113179 12482968 15615775 8616895 12163591 11971985 16713569 16860316 14722092
KAT2B CBP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9445475 11864601 9710619 9267036 9687513 8684459 9687573
CBP FOS â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11782371 35140242 16055710 10487758
CBP PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17239008 25733689 12234245 12142048 10077561 12622724 16713569 10610177
CBP ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18765668 14766010 11113179 17400812 8616895 9192902 11782371 23403292 16417649 27420286
NCOA1 GCR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31182584 10659697 11266503 12917342 12118039 16606617 12569182 28611094 10731636 16713569 16423881 9590696
GCR NCOA3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31182584 11266503 12917342 28611094 18160712
MYC CASP8AP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
SUMO1 CASP8AP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21338522 19615980 23673342
UBE2I CASP8AP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21338522 19615980 23673342
PRKACA H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11749379 9892015
KAT2B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34811519 16096646
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
TGFB1I1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10075738 11532379 21515881
NCOA3 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10965917 17108143 19305643
AR SENP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25014244 17932034 19116244
AR PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18386814 16317058
AR NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21273442 20610535 23689136
AR NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315100 15219414 20610535
AR SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24119295 21796528 17932034
NCOA6 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14645241
AR KLK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15542435 1370633
EP300 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12573436 10999956
ARNTL SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12738229 20969520 19168071
ARNTL PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15828232 16556735
RORC ARNTL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18454201 23555304
ATR IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21872579 18583959
CTNNB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17404573 16288908 12782598
ESR2 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19211725 18223478 20664923
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 MSH6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11498787 16260778 25184681 10783165
NCOA3 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14966289 22977234 15988012
NCOA2 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14966289 16344550 15988012
EGFR CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19446582 15657067 24658140 31980649 22411794 34079125 16407214 12354760 25402006 10781609 9374534 12388423 16799092 15273741
CAV1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23634843 11563984 22230296 19595769
ETV4 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15138262 19483189 17390339
ESR1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12138116 18414489
MYC CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10918582 18444242 11258956
SOX2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18456656 25482558
THRB CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15601836 18037966 12951064
NCOA3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11358796 19095746 15808510
TBK1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10783893 21138416
TP53 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17003465 24192518 16917063
NR5A1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10770490 23358192 9468515
RARA CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23321499 16417649 21110951
NCOA2 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14966289 11747826 16613851
CREBBP HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10777539
SOX17 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10549281 15163629
CTNNB1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 21362399 21986938
CTNNB1 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12944908 25241761
MYC CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10229837 11145693
ESR1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15358113 15499176 18299335
PKN1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21749319
EP300 HNF1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 15598887 11978637
EP300 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11796223 11062529 9001254
RXRA EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15766748 21138976 11297512
NR2F1 EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7891708
SRC ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 19704002 21075308 7542762 7797556 19372587 29720121 11940572 17875712
NCOA1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19383905 10698518 19109434
NCOA3 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18484708 20181721 19491275 10490106 25728767 26166704 12554772 18645020 16923966 16331275 16713569 11376110 21182203 23403292 11050174 9192892 26487511 28844863 11353774 15145444 17158759 11389589 14966289 9346901 26153859 17646391 20392877 15383283 12630920 9765300 12714702 14766010 30418174
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9259327 10409727 23874500 11014206 15604093 12554772 16282588 9427757 11113179 18451880 9121466 10598586 16713569 11165056 14715875 11376110 9774463 10760302 20608937 9192892 11003650 26487511 11867769 10454579 12574227 17363140 9773983 10731636 11358671 11250900 11682626 23975195 17627277 16606617 12630920 12714702 9192902 12738788 16957778 15140878
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
SRC ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17043237 17284441 17400812 15604093 11032808 17921256 18451880 15020686 12736255 11564893 23065768 10454579 20935677 17363140 16957778 14963108 11013076 29720121 15784253 24498420 17627277 12630920 22328528 14766010 24051437 7539106 27420286 15140878
ESR1 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28539435 18657504 11029009
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
ESR1 PLAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19652226 24304549
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
ESR1 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664452 17556531 12710998
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
NCOA3 ESR2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11500849 10681591 17158759 9765300 11376110 11389589 12554772 21182203
ESR2 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20155458 10037443
ESR2 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
ESR2 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664452 17088408 17556531
ETV4 NCOA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22505454 18644862 18593949
FGB SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
PPARG FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10678274 23657115 18059282
FOS SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8917435 11223948 12390531
FOS PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10535756 1331087 1663213
RXRA HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11027556
KAT2B HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10777539
NR3C1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17978169 24399729
RXRA HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10744771 11027556
IKBKG IKBKB â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 8209688 506093200 16126728
MYC KAT2B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 12660246 15572685
NCOA1 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12163591 10809234 10777539
NCOA2 MSH6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14662770 10454563 11747826
NCOA1 MSH6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14966289 10454563 11747826
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC STAT6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SLA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC UCP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12695333 11085504
RARA NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12138096 16456540 9192892 23975195 9121466 10454579 16606617 17475621 21478865 17363140 20543827 17641689 16713569 10082574 10760302 12665583 20338915
NR1H4 NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14698205 11136553 18391212 20338915 14684751
NR1I2 NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15331348 16455805 12072427 17429319 19171678 18096694 23602807 23160820 15604093 12909012
PPARG NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10347167 15604093 15026545 30813326 11877444 19596656 17704298 30595551 9041124 9121466 9744270 23178929 10339548 16713569 15888456 17513608 22070604 17449869 10731636 20717101 10848596 17468099 11027271 17312272 11500849 23975195 17011503 16373399 10944516
NCOA1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 17400812 17495236
NCOA3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 12650696 17671194
NCOA6 SRC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10567404 10847592 12482968 11158331
NKX2-1 SFTPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12040027
RXRG NR1H2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR1H4 NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16682417 21476904
NR1I2 TNFRSF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
RARA NR1I3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20211151
RXRB NR2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 10900149
NR3C1 NR4A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR3C1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15956716 15289446 16557033
NR3C1 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16423881 12902338 10518526
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
PPARG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NR3C1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NR3C1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21900206 23331499 15591535
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
SUMO1 NR5A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15192092 15192080 21467194
UBE2I NR5A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15192092 15192080 21467194
NR5A1 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23471216 23340581 23537609
NR5A1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8825555 12697703 12697699
NR5A2 SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20159957 15923626 19692572
PGR SUMO1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19211567 17717077 17020914
PGR UBE2I â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19211567 17717077 17020914
UBR5 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 12011095
TP53 PIAS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24584189 11877452
SUMO1 PML â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15017387 15561718 28851805 16501610 19217413 22155184 22875967 24654937 31879127 21779164 20188669 9885291 9452416 17081986 21098080 22406621 18625722 21305000 17344210 17027752 11160742 19380586 23604351 23830076 17081985 9427741 11080164 16189514 23028697 21057547 19015637 20972456 8806687 20826694 24190887 25497731 17036045 11948183 9756909 18474224
PML UBE2I â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14992722 18056437 14715247
RXRA PPARA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15888456 12562861 7760852 34081964 10195690 22205725 23711995 16189514
RXRB PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8384714 23331499 11237216
PPARD PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20097210 10991946 20176998
PPARG TNF â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 10432118 17681149 23390297
SIRT1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15850715 21633182
PPARG RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12839938 18075297
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
STAT6 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17237818
THRA RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
RARA THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
VDR RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10342883 10224118 10336890
THRA RARB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
RARB THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15650024
VDR RXRA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10733574 15604093 12847098 17500032 17786964 12796488 15829977 15647825 20153625 11075811 15888456 9632709 21988832 27728806 15890193 10224118 16750418 16357103 11514567 20564192 14726489 15805579 26329759 11149488 11124027 21478865 10037600
THRA RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 8127707
RXRG THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 8127707
TP53 VDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16462763 16651407 18431400
CREBBP HIST3H3 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
KAT2B TP53 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
NCOA1 VDR â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
NR1H2 RXRA â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CREBBP CTNNB1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
HIST3H3 KAT2B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
PSMB9 PSMD4 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CTNNB1 NR5A2 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
ESR1 NCOA3 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NCOA2 NR5A2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
NCOA1 RARB â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
HIST3H3 KAT6A â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
NR1H2 RXRG â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
RXRA RARA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5212283 10698945
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
NCOA2 PPARG â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
NCOA2 THRB â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
RARB RXRA â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
NCOA3 CBP â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21914189 9445475 17043108 9192892 11823864 33589584 16227615 8616895 9267036 15383283 26267537 11971985 11076796 16713569 9346901 21632823
NCOA2 RARA â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
NR1H2 RXRB â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CREBBP SUMO1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ESR1 NR2F1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
NCOA2 ANDR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12588987 15684378 9717843 10454556 14966121 33640491 12612084 15563469 16713569 10935543 14593076 12810069
NCOA2 GCR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 31182584 11266503 28611094 12151000 9920895 9590696
CDK9 CCNT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 14627702 23455922 19914168 30652970 24981860 14580347 21697490 20535204 11713532 22939629 26659056 22959624 11145967 16980611 15713661 23602568 12115727 11689688 17643375 10574912 9499409 12832472 20305087 30649429 26344197 10617616 27684187 18483487 9872325 19818711 16109377 12894230 15328539 12944466 15546612 32707033 15713662 20153263 19387490 18566585 22483617 21729782 20562857 24367103 28514442 15528190 10465067 11713533 10958691 9491887 17700062 23064645 26186194 11282025 12588988 15107825
EGFR EGF â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 25453753 30083275 21822280 12620237 19531499 25080504 12093292 22729867 23597562 18427122 26280537 18271526 10970856 15620700 11684674 21439278 8663535 28988771 2790960 10788520 10085134 16274239 25241761 17697999 9135143 12297050
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
NCOA2 ESR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12837248 17697320 11014206 12554772 18499756 15657427 11265755 9430642 11376110 9774463 16645043 9192892 11937504 26487511 12612084 19460354 20348541 11250900 12630920 12714702 14766010
CREBBP NCOA1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CREBBP PPARG â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NR1I2 RXRA â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RXRA THRB â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
AR NCOA2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CREBBP NCOA3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
AR NCOA3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ESR2 NCOA1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 PPARA â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 NR1H4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 NR3C1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PML SUMO1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
AHR ARNT â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
NCOA2 NR3C1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CDK4 CCND3 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 8153045 21516116
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
IKBKB IKBKG â—¼   PHOSPHORYLATION ✅ 0.98 0.98 mint 8209688 16126728 506093200
NCOA1 NR1I2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PPARG RXRA â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RXRA VDR â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SENP1 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EGF EGFR â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NCOA1 RARA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NCOA2 RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RARA RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NCOA1 PPARG â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ESR1 NCOA2 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
NCOA1 RXRA â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
ARNT AHR â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 10619402 33961781 7628454 11768231 19390533 22138065 10395741 26350169 20006590 10617682 31675361 11259609 23477502 17392787 12139968 9887096 8631989 28514442 9704006 8065341 18096572 8621524 7488247 8619634 11025203 10671489 11551916 8384309 12024042 19380484
CCND3 CDK4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IKBKB IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNT1 CDK9 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TP53 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17530187 19861536
CTNNB1 CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
CCND3 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 11896535 25416956 16985050 34591612 21988832 14597415 17517622 16782892 10342870 21516116 23880157 15232106 16189514 11360184 26496610 25910212 26186194 27107012 10477583 19237555 32296183 14641107 9106657 9508775 31515488 9716181
KMT5B H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24396869 15765097 15550243 19218832 18022353
MYC CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7739536 10931841 11673469 10657901 12177005 14519204 9111322 9811896 10567564 17706770 24771621 11983916
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
PRKACA CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 19651622 17081983 1359877 18767875 17322306 18691976 4092695 19664994 20068231 18707149 23429703 11986331 17206380 14991569 19664995 18669648 33771897
NR5A2 H3C2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
H3C2 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
CARM1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15345777 15471871 16497732 11751582
NR5A2 H4C6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
H4C6 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
CTNNB1 TBXT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10704849 12032083 12234972 14575694 18948405 15292219 15579438 16139800 14557550 10953028
HNF4A G6PC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12651943 11544200 15933209
NR3C1 G6PC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22457708 16037130 26652733
HNF4A G6PC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15591035 11864989 22384829 16308421 12651943 15933209 14722127 19720831 15388792 15702243 12915406 18805788 20577053
HNF1A G6PC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11864989 12760745 15933209 9839806 11544200 10766845
PPARG ADIPOQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 19843873 20668453 19324019 19833717 20473515 12829629 15764598 18804108 19954946 11533050 16803864 20622112 18296319 18373719 12927809 20484463 23381555
PPARG ADIPOQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12829629 20592862
AHR TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17070097 15111621 11191113 20478272
AHR TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11470802 17588258 25690886 19703987 15627257 20181658
AHR FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14973392 10478842
AHR PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18001219 12548657 15213229 19056653
ARNT AHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8621524 8384309 9887096 20006590 10395741 18096572 12024042 7628454 9704006 19380484 17823304 11259609 19390533 22138065 8631989 8619634 8065341 11768231 7488247
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
TBK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21329883 21464307 21106850
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
SMO AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20016067 20643644 20956384 21209912 18820483 17641202 17688959 18997815 19549984 19592253 16537363
AKT1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
AKT1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 23331499 17680028 20214616 17688959 20398329 16537363 17052453 19575820
AKT1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 25581517 11274386 16223362 17570479 16713569 26155943 18669648
AKT1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15184909 25241761 22689577 15856005 10485711 17660512
AKT1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27997540 24291004
AKT1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16417524
AKT1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20837477 20098747 17660512
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 15710601 12048203 25241761 19442713 11278366 10485711 15800029 19609947 17570479 17660512 18515365 19088076 10485710
AKT1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17428466 20832017 20085797 21242970 17570479 10542266
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
NCOA1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15514032 12163482 23145053 11673464
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12237244 8824277 19074897 11049111 17374439 11410519 20610535 19363165
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18511414 8580999 7522959 15590903 14662770 18692155 17374439 18212060 20610535
AR KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17433535 8626436 11059779 15640443 7686046 11006269 12111703 15368351 24307657 9316650 9719026 11867260 12376473 14767470 16275987 11994312 17075604 20181722 9211894 16342680 12917209 18092350 12648523 17011549 11238180 20069563 10547578 16140973 22245379 12539223 20568894 20103546 18758709 21981678 21541973 12463425 12958311 11894840 19389135 17534890 23662037 15923603 16434977 14517289 22695118 10075669 11377978 16137620 11299734 15131260 21780100 16508948 16425097 22473899 14715080 10625666 18640093 21885566 12670590 14729601 16452400 16081584 10898343 11571582 9044850 15833875 16914734 23884959 15640095 15543614 7514587 12376534 12114445 15557561 18780293 23667504 18829551 12782640 16724108 17426252 11504717 19274665 11034093 17566103 12651911 22179832 21308712 16373397 19013180 22155408 9052414 11532861 17094454 17653089 20709811 22654108 22597536 15514031
AR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15305378 19318561 21613411 19258514 15650253 17242169 18692155 15288768 11556855 20610535
AR THRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
AR KLK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11532861 20688158 16020662 7686046 9241247 1370633 16751804 23884959 20103546
AR SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19305643 10454563 18687691 17108144 17079466
AR ETV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17634427 19789348 20610535 17505060
AR BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17655826 11567031 23160675 20610535
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
AR CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9822653 15350180 16492776 16344550 11161315 18819102 18031230 20610535
AR KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19460858 20610535
AR KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18945670 20610535 11328859 23095762
AR TNFRSF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
NR3C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
CREBBP AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20541699 9822653 15691881 12810069 9482849 16713569
NCOA2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9717843 12588987 15684378 14593076 24239470 15563469 18780293 12810069 16713569 10601285 14966121 10935543 10454556
BRCA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11085509 16713569 11016951
KAT2B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504
TGFB1I1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11155740 11779876 11856738 8643607 16713569 10075738
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
NCOA3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 14966121 11747336 15563469 16713569 10965917 21047772
SRC AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 28144231 15062576 20570899 25133482 21318111 11032808 25950519 21512132 17525795 12933816 20383201 24728074 24948875 24868554 25547388 19117998 21956655 17045208 15027889 24859991 15466214 26829214 21886458
AR KLK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1712248 19345326 25241761
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
AR NR5A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 11518799
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
AR NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 9162033
AR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18358509 12534934 22260327 15288768 18951974
ARNT CREBBP â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 11959990 11063749 7836384 11959977 9632793 17804822 9822602 10202154
ARNT EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8089148 10207038 20631191 11782478 8663540 8408001
ARNTL SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24442997 19897060 25309798 24089055
MSH6 ATR â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
ATR BRCA1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR WDHD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27940552 26082189
ATR BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 26927092 17478428 24746700 15159397 17531442 10866324 18677104 19622404 15798197 19793801 20860841 16713569 11114888 23422745 20936109 16322207 19282663 20068231 17116885 17582221 25879655 10608806 17384638 23346553 12773400 12183412 17525332 15459660 11278964 17296725 11877377 17102137 10550055 16522651
ATR TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17145710 22778941 24395704 28468838 12401524 15159397 24877058 15254178 9733515 11483158 15806145 19056039 11875057 15865930 11551930 11883897 19923893 12548019 18697815 29170437 16293623 19010925 11709713 10446957 9363941 21748595 17272272 22797063 12242661 10196661 22084686 10747897 10608806 10673501 12091386 17118344 23892398 9765199 15489221 24037342 15140942 10435622 17241873 10597277 10801407 11711532 17174997 21593792 25201202 9843217 10606744 15024084 15226429 15922368 21415014 21480565 15585169 24947324 9925639 23380594 9733514 11865061 19625493 16390936 10951572 10570149 23311997 12111733 26144601
BCL2 NR4A1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11704864 14980220 17446862 22039431 23064052 23377657 23430059 23850759 8929532
MYC BCL2 â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
TP53 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17693666 8183578 10037739 16738310 18397889 19521340 18487508 21666495 16294215 21656028 22869582 19714248 10744634 8174112 17592775 11782367 19137013 20428827 18682598 11713302 11313951 20501806 9649502 24814047 15767042 24098340 11193470 10329733 21859835 22266868 10953306 19555669 23638218 14684736 19411072 20530667 24155778 8205530 20840522 9000137 15326476
PGR BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17785366 9306964
PPARG BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15067355 14960510 15878253 19956851 15094967
MYC BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8036017 17404573 12695333 24167291 18809243 19201832 16316993 19649202
ESR1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19148464 19160418 9306964 11261829 21841772 10542244 20664923 18414489
CREBBP BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9829964 10753867 17565603 15337521 10454566
TP53 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12667443 19555669 8205530 19007744 11313951
NR4A1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18835031 14980220 16434970 16713569
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
BRCA1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20160719 18851829 9000507 21407215
CDK4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9244350 16713569 17334399 20932174
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
ESR1 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
CARM1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15731352 11701890 12374746 17043108
CARM1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15731352 21988832 11997499 11701890 15616592 16923966 18280497
CARM1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18188184
ESR1 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11773442 17535799 15033483 22031296 15496458
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
TP53 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10684646 20610713 17014845 11076533
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
TP53 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 24189068 8702807 10669755 22270849 12808109 17942917 19086036 20731879 16061648 20554748 24460719 11798189 10082575 15205322 18769160 19800042
FOS CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 19847806 22550166 15994929 21474819 23157741 15282324 11287611 20188076 9710644 14508521
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
ESR2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15313930 14764652 18607069 23891847 11986316 18223478 14729654
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
CTNNB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16628468 10318916 12095419 15111320 15735151 18679417 17360646 12782598 10201372 14557550 19778454 20300972 19662654 12589056 11943708 10915780 17693601 15592430 17109766
PPARG CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23455892 18927468 14764597 15486348 11287611 20651819 15041706 19075513 15193259
PGR CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22396492 22892083 15282324 20479568 22542550
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CTNNB1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 11836555 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 17208333 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
KLF8 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
HNF1A CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
CHUK CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 10910956 17666529 9832503 23343194 21285352 18974774 10766840 22761862 22290435 16039586 16103118 19619488 19623618 15212693 17143292
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
CDK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24173284 9372954 11483158 9315650 19413330 19664995 23603988 24202322 11709713 16083285 1088347 16552184 10884347 24286312 10747897 17942552 16741955 17287340 92065884 12064478 10348343 14702041
CDK9 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22158970 33593309 29170386
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
TP53 CHUK â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15469934 11557753 17434128
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
TNFRSF1A CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23815148 21724995 10795740 24323043 10755617
SRC CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 12707358
CHUK MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CHUK NCOA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17145710 19651622 16135815 15808510 11971985 20068231 19413330 22505454 16964243 18669648 15383283 15302935
CHUK CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21674813 17145710 14597638 17434128 22435559 12789342 27220480
CHUK IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 9346484 24911653 20932476 28514442 11971985 16970925 12210728 9346485 17965022 16713569 12486103 9891086 15456791 11057907 20434986 16129692 16260493 21903422 21724995 16286467 14743216 16319058 18949366 10779355 25748427 25852190 12244103 11585904 9751060 15218526 10094049 10837071 9914500 21575199 9721103 25241761 10195894 9689078 15214841 21784860 17561400 21640763 16285893 10733566 16186825 16493424 10022904 12709429 12351658 10968790 12547194 15691841 15620648 15327770 11864612 11460167 14636585 17693255 17072322 9346241
SOX6 COL2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16465043 20181744 9755172 10980415
CTNNB1 CREBBP â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
NCOA3 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10777539 14966289 22977234 15798179 22608253 11747826
NCOA1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10777539 15671023 12748280 11463834 14966289 19194461 9792627 18193094 11747826 17400812 17244199 9223281 10594042
NCOA2 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 15657427 15987788 9192892 9430642
KAT2B CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9687573 8684459 9687513 9445475 11864601 9267036 17496784
CREBBP STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11509556 15695802 11574547 10454341
CREBBP KLF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18500350 16713569 12682370
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
CREBBP NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 15657427 15987788 9192892 9430642
CREBBP CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10769018 21751375 11973335 17410209 18347063 16476742 23273993
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
PPARG CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12021175 15190077 20303941 14764597 19075513
CTNNB1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11396184 15592796 12154096 17945188
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
RXRA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12771132 25241761
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
ERBB2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17496910 7702605 7999105 22558232 14517306 11245482 11950845 12040186 19568798 23576562 14585353 23640056
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
CTNNB1 HNF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12107263 11266540 23331499 15055546 16442529
CTNNB1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25721714 16847334 25168821 19495794
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
NCOA1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17429319 18299335 23179081 19077665 16455805
NR1I2 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 18805405 17526937 15499176 18299335 20538721 15367577 18096673 12542705 15269186 10935643 18784074 11329060 12417264 16013442 11602528 19171678 16455805 19077665 19934400 23732298 23807564 23928187 23891548 21920351 17293382 11991950 9727070 15180306 15698577 17764444 21292004 11602521 11336976 12781341 12606758 10403778 12167569 19712670 12664659 22982774 21311750 20736322 16219912 21342487 21733184 19129222 19138736 19232333 23179081 22976785 19686701 15650019 11581012 23536728 12130689 12601364 15523048 16608838 17035600 12072427 17429319 10570062 18332045 12851153 10772626 11114890 20171174 15100175 12514743 10611146 20942813 19074998 18540626
RXRA CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19712670 18400206 16608838
VDR CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22939842 11991950 18400206 11723248 19712670 12167569 19581388 15358113 12147248 15205382
NR1I3 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20580705 18805405 12130689 15698577 18677425 20642445 11114890 12167569 12514743 15990349 12664659 19686701 22363234
HNF4A CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19077665 20926756 21952236 14742674 17764444 15698577 17344340 12514743 16455805 19934400
HNF1A CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14742674
NR3C1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18805405 7499421 17572486 10772626 11602528
HNF4A DR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17464991 11222753 16492670 11549270 18305375 10787435 17485727
EGF EGFR â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
ESR1 EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10894157 15075211 20889718 8770893 19423651
EGF ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15748904 23331499 12093292 11279155
EGF SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23349873 19481075 15845350 22927910 27462789
EGF EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 131.0 1.0 Omnipath 17145710 17081983 21822280 20813200 23613900 9135143 25453753 21303971 10209155 26821125 12297050 27387652 25241761 30083275 12093292 30197274 21649524 19531499 18762250 16729043 26921391 17697999 17575160 21722395 12620237 19129184 10788520 23331499 3494473 15620700 14568001 15958209 24096486 18253097 16843263 18320059 21532939 10085134 22260327 15708576 26280537 23912460 21858221 11116185 10970856 27462018 18427122 25080504 20953304 19135477 11684674 8639530 27564112 18270696 2790960 17971399 23185569 19895983 28988771 29617357 23597562 19531623 23950932 21071413 8663535 6289330 16274239 17563729 21439278 20458382 22216880 18271526 12771140 21311755 24709886 25366117 12648462 21107857
PTGS2 EGFR â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18633355 20138012 21847358 23010081 23390297 25987127
VDR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21458521 16087726 15218361 11967012
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
PPARG EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15486348 18332871 18288266 23370527
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
PGR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22542550 8347631 16449295 17074804
FGR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 31980649 24658140 11160627 25402006
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EID1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11073989 11073990
EP300 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12057991 17395887 17237818 12471036
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15731352 20448036 10490106 9920895
EP300 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21988832 20438716 12082103 16713569
EP300 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11509556 15145939 10454341
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
HNF4A EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9027736 14741200 21988864 9371982 9510530 7891708
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
ETV4 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11175365 18409049 10655108 16406575 7914192 16786139 17168666 15235125 15461591 11774202 16632435
MYC ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20920219 21627565 7906953 23421821 20716114
PRKACA ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18799465 9855018
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
ERBB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16769082 19617202 11940572 12753909 21075308 7542762
NR5A2 ESR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
ESR1 TFF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21984905 19858291 11517191 18543253 19935720 17317669 22382029 18414489 17938209 19462000 18322535 22093877 16219765 19933843 16087863 15541729 10037443 22543272 16651411 20422012 23874775
ESR1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8300756 8912864 8732679 11038749 15831516 15870697 10076999 9626663 18414489
ESR1 UGT1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10854430 23714156 9773976 12114525
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
ESR1 PSMD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18457947 9253789 12648521 11696545 23580568
ESR1 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23911789 19376833 16091743
ESR1 ESRRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12960079 18174157 20211987
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
ESR1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 17641689 15831516 9717844 9841885
ESR1 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18499756 9192892 9430642 11014206 19460354 15657427 23331499 11477071 26487511 16645043 12612084 20348541 12630920 14766010 17697320 11937504 12714702 12554772 9774463
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
ESR2 TFF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11517191 16219765 10037443
ESR2 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16293641 12761896 11014241 19001520 9717846
ESR2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11013076 12095943 12630920 11032808
ESRRA TFF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16024613 19462000
PRKACA ETV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 12569367 23774214 12917345 11551945 12213813
ETV4 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11901151 24983502 21150337 11274170
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
NR3C1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16850320 9804760 1314076 8036015 8890955 8733011
FOS POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8793851 7894465 8592520 1331087 1663213
FOS TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19285436 2506186 16834785 22322974 10837498 12057991 9030359 25567680 19026727
FOS IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10037779 10542237 9671466 2511437 25567680 20351184 24994901 11356008 11028561 12667961 18502099
FOS PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15772294 11278336 9620167 17556653 12057991 8906578 17440114
FOS PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16293641 14684847 12446585
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
PRKACA FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9920881 20068231 18452278 8248197 1545828
NCOA1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18511550 10847592 9642216
HNF1B HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15486044 1363228 16793932 15001636
HNF4A HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8367288 9111350 9792724 8674436 11717395 9313764 9837989 9204893 9232592 1734282 20850486 8735941 11145965 11085951 10331424 8808405 12601360 16670373
HNF1A NR1H4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17507182 22290433
HNF1A UGT1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16399341 19541828 20096102 18172616 10462540 9052741
HNF1A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
HNF1B HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10518495 8290348 11585914 16479257
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
HNF4A NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12774017 15331348 12601364 18305375
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
HNF4A PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11981036 15912134 19933841 17022998
SRC HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16713569 22308320
TBK1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10783893 21903422 21138416 10195894 14743216 16207722 10022904 14560022
IKBKG IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 150.0 1.0 Omnipath 17145710 16938294 20932476 35339487 18266324 16260493 27929056 25979343 19666608 26496610 12133833 12192055 9751060 21423167 19706536 15836773 17561400 22099304 23986494 19959994 15327770 25400026 24266532 18450452 12657630 20434986 11583588 20200955 20300203 21903422 22990857 14743216 20167598 20098747 16126728 19656241 25852190 16906147 10195894 17000764 18329793 16186825 16547522 16611882 18037881 10968790 16497931 25286246 18462684 18207244 16603398 17965022 17977820 24240172 17568778 15084594 16129692 23506214 16319058 23123196 18949366 15218526 22605335 20368414 10837071 19820708 10980203 23131831 17363973 15214841 25304104 16493424 15184390 15691841 11864612 15802604 17693255 21455180 11865184 20211142 11971985 16970925 24469399 24618592 12486103 11057907 24369075 19365808 18583959 27426725 12612076 19422324 10094049 23109003 21803029 12459277 21640763 16285893 18266467 12709429 15620648 17072322 19815509 15749833
SRC IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 12645577 12707358 15456896
IKBKB NCOA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 19651622 16135815 15808510 11971985 20068231 19413330 16964243 18669648 15383283 15302935
TNF IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
TNF IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
IKBKG IL6 â—¼   DOWN_REGULATES ✅ - 38.0 1.0 ACSN 10542212 10754326 10952726 11875494 12133805 12907458 14660645 15199157 15465827 15485931 15536066 15644117 15749903 16243976 16413922 16818229 16878026 16970925 17237376 17254973 17363905 17404308 17485448 17693255 18716620 20138012 20300203 21217011 21807870 22435554 23086447 23390297 23422957 23430059 2649237 28462531 7594497 9743347
TNFRSF1A IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 10755617
IL6 TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
NR3C1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19436110 8175711 27371733 11459775 8290595 21474440 2233715 1871124
NR1H4 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19028791 18981289 19118524 19864602
TP53 KAT2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9266967 20094059 15153330 17611664 18945670 14614455 17293853
KAT2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 19680552 11804596 12068014 16537920 9891054 10490106 14614455 20589832 19788416 12660246 12501250 16959611 19407812 9744860 15965232 16678111 17977830 17189186
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
TP53 KLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15540784 11791186 11504717
PPARA LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10774955 15713663 12208475 10634806 8895578 12042669 9226459 14960661 16890192
PPARG LPL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17658475 10098492 8895578 18948972
PPARA LPL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20813756 18391971
MYC STAT6 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
PGR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8701093 9408078 22396492 9305935 22892083 10651641
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
MYC SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12695333 18414489
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
NCOA2 NCOA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
NCOA1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11698662 10731636 9626662 12163133 21775429 15888456 9407140
NCOA1 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12529333 7481822 10757795 19706513 21273440 16352595 16728408 10722692
NCOA1 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12612084 23975195 17786964 15604093 9878542 11124027 11149488 9121466 12403843 12796488 10224118 11075811
RXRA NCOA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
NCOA2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12612084 20543827 23331499 9192892 9430642 16713569 12503607
NCOA2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 11500849 9238002 17513608 21071413 15026545 18988627 18584035 10944516
NCOA2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 12612084 11981034 15657427 23331499 21071413 9430642 10748178 11514567 18988627 11851396 17947383
NCOA2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11266503 29170386 12151000 9920895 9590696
NR5A2 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
PRKACA NCOA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22505454 15383283
NFIA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12145335 10505791 10634504 8816507
NKX2-1 SFTPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12161428 9252399 11274148 20418387 8065304 11152647 9396717 10710519 18003659 16500948 19906647 9211870 9006959 16183668 16507635 16960125
RXRB NR1H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 15604093 10187832 14993927 16189514
NR1H2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 15604093 21071413 24561505 9199332 7760852 16189514 18988627
RXRA NR1H4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
RXRA NR1H4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 19883617 7760852 10744760
NR1I3 NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10924340 15557560 14683479 22363234
NR1I2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 9727070 15604093 11706036 9489701 16189514 26855179 23160820 22976785
NR3C1 NR1I3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15382119 16608920 19630272 12511605
NR1I3 UGT1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12114525 15557560 11343253 19541828 18172616
NR1I3 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8114692 23331499 12130689 12896978
NR2F1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1311101 23331499 10900149
NR3C1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24811171 27777311 10649448 8754811 11279134
NR3C1 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17043312 7894465 2626052 2998878 15591535 3326882 2167656 11174853 8994186 2586521 8386673
NR3C1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10631313 18945810 10827178 18657608 9918831 19797430 10701683 18650268 16198345
SUMO1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 12193561 12144530
NR4A1 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12970370 10811295 14729605 9496246 15063754 19321449 9315653 9315652 15591535 15701640 15319449 8380897 11174853 8994186 9699858 10875239
RXRA NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 14980220 10772826 17761950 7705655
NR4A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23071566 17139261
SUMO1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22875967 9756909 25497731 17036045 21057547 18931695 19217413 8806687 16189514 17081985 11080164 11948183 9885291 19380586 17344210
TP53 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17350573 18510673 19098008 19449448 17630965 24917821
PPARD PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18445701 19483106 11867749 16288226
PPARA PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11840453 12388637 11971025 18648741 11578780 11412039 11007963 20022932 21323895
PPARA SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20400680 15631825 9869165 12667383 20969520
PPARA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12941763 16226723 20706641 17261671 18769491
PPARA TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11009565 17463321 17260462 15669179 19039651 10377130 19640904 19576184 15891579 19225884
RXRA PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 10195690 12562861 16189514 11237216 10708554
PPARA RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22205725 23331499 16169070 15130092
PPARD PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17178883 17693664 18566335 16966336 12901877
RXRA PPARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 22205725 23331499 15604093 9933587 19756148 11237216 15888456
RXRB PPARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22205725 23331499 15604093 11237216
PPARG STAT6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
PPARG STAT6 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
PPARG TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20376096 11009565 14646597 20473515 11124825 17532302 17464333 19031802 14656714
PPARG SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 10329404 15990085 18278065 14581151 17906687 17995524 10073956 16843437 11230363
PPARG PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11278336 16506021 19578162 20234816 10827178 14555539 11412039 19997048 20656057
RXRA PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 12763030 25609649 20211142 11877444 16504037 17579352 16713569 9065481 22205725 23331499 22363753 10854698 19147680 19043829 12591919 9568716 10882139 10935544 17980149 26260846 21478865 14587029 23711995 9121466 18217139 31547433 7838715 19047629 23275339 21833030 12966085 17312272 11237216 15888456
UBE2I PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19692572 15507114 26192107
RXRB PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22205725 25609649 23331499 20211142 15604093 11237216 18988627 10882139
SRC PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 30323259 10322133 26385316
PPARG RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12615696 16189514 18988627 15130092
SMO PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20016067 23331499 20643644 20956384 21209912 18820483 17641202 17688959 18997815 19549984 19592253 14611647
PRKACA RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16769902 7476969 20215566
PRKACA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11162439
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
TP53 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21187340 16713569 11687965 21763744
RARA RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10929206 16613989 7969156 8388240 2164682 1316240 8001825 1650576 16832676 16782888 10629053 2153268 9108446 1318502 10629091 11839811 11497266 9184230 14528273
RARA SFTPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15044588 11274148 10070102 10617585
RXRG RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 21988832 25910212 25303530 23331499 20211142 15604093 21071413 10529278 21516116 25416956 31515488 16189514 32296183 16713569 18988627 29892012
RXRB RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 21988832 26871637 25303530 23331499 20211142 15604093 1310351 21071413 10721822 31515488 16189514 32296183 16713569 18988627 29892012 1310259
RARA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 15528208 19345331 16713569 16769902 21988832 23331499 14521715 15604093 21071413 10828175 10698945 18988627 12393611 25303530 16224062 25241761 1310351 21478865 17641689 7760852 9415406 9121466 7705655 9582446 15171703 10882070 1314167 12052862 31700049
RARB RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20102612 12576329 23331499 7565739 1310351 23180781
RARB RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9006910 20211142 15604093 25416956 31515488 16189514 32296183
RARB RXRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26871637 23331499 15604093 1331778 1310351 12112017 25416956 32296183 1310259
VDR RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 14726489 16357103 17786964 16750418 11514567 20564192 11149488 12796488 21988832 12847098 23331499 15604093 10037600 11094341 9632709 20153625 21478865 10733574 11124027 15829977 10224118 17500032 15805579 22179700 15888456 15647825 11075811
THRA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11018031 23331499 15604093 1331778 1314167 19422879 11117530 16189514
SRC RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10322133 23331499 15140878
THRB RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9582446 23331499 9368056 15604093 10677278 19211732 9162076 19422879 7746322 9171239 9415406
RXRB THRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 10976919 15604093
RXRB VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 23331499 15604093 10721933
RXRB THRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 10976919 1331778 10721822 16189514
THRB RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10976919 15604093 9794455
VDR RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11713233 15604093 15919723 32296183
RXRG VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11713233 15604093 15919723 32296183
TP53 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 23665346 23063463 7479001 11470783 20947822
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
SNW1 VDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12840015 11514567 12529369 9632709
STAT6 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17878383 10227996 9092569 16004996 11254707
TBK1 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 30223576 22000020
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
TNF TNFRSF1A â—¼   PHYSICAL_INTERACTION 33.0 1.0 ACSN 11112697 11274345 11279185 12531547 12646658 1330325 1431106 14607933 14625680 15099563 15310755 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 21920725 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 26801188 28765050 8663014 8910423
TNF TNFRSF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 98.0 1.0 Omnipath 17145710 19084540 8288897 11448951 23746843 22801493 14732063 2848815 9568681 2158863 8182064 9488135 23070005 20080539 11239407 26670046 14743216 21724995 21133840 24070898 25911380 7852363 2170974 17151142 26186194 27560715 25241761 23032187 24726327 20103630 8805640 11502070 19442713 3034874 23955153 18067990 22099304 15485837 22675546 12753742 1310388 12887920 19287455 10634209 2170559 1331108 24980434 22028622
MSH6 MSH6 â—¼   KO_DOWN_REGULATES ✅ - -5.12 5.11 PKG 28854368