PAK3
|
VAV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
PAK2
|
VAV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
PIK3R1
|
VAV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7033842
16982329
|
VAV2
|
VAV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
VAV1
|
VAV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
VAV3
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
PAK3
|
VAV3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
PAK2
|
VAV3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
RHOA
|
VAV3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18589439
8990121
|
PIK3CB
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
PIK3CA
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
PIK3R2
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
PIK3R1
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
HLA-C
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5211709
10429675
|
B2M
|
RAB9A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
PAK3
|
ARHGEF7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9726964
|
CLTC
|
ARMCX3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
CANX
|
RAP1GDS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CDH2
|
IQGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17098867
0607299103
|
CTNND1
|
CDH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8660921
14610055
|
CYFIP2
|
CYFIP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
11438699
5214235
|
WASF2
|
CYFIP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15048123
5216987
|
CYFIP2
|
WASF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15048123
|
DAG1
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
EMC8
|
EMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
JAK1
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
ERBB2
|
VAV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
ERBB2
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
8026468
|
ERBB2
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16273093
|
GJA1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11035005
5213074
|
GOLGB1
|
GOLGA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
VTI1B
|
GOLGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
GORASP2
|
GOLGB1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
20608975
7897361
|
HSPA5
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PI4K2A
|
ITCH
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23146885
8426259
|
SLC16A7
|
KTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
LRRC59
|
MAP4K4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
LRRC59
|
RSL1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PIK3CD
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
LYN
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
LYN
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218167
16374509
|
LYN
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
LYN
|
PIK3R5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
LYN
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
MAP3K1
|
MAP2K4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6548305
9808624
|
MAP2K4
|
MAP3K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7855889
7997270
|
MAP2K4
|
MAP3K1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
6548305
9808624
|
MAP3K11
|
MAP2K6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
9003778
|
MAP2K6
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11460167
10882101
|
MAP2K7
|
MAP3K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11306453
9639556
|
MAPK8
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7033842
16982329
|
PIK3R1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7642542
16982329
|
NCKAP1
|
WASF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15048123
|
NFKB1
|
TNFRSF10A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21243522
|
VAV2
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
VAV1
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
VAV1
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
PAK3
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
VAV2
|
PAK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
PAK3
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
PAK3
|
VAV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
PAK3
|
VAV2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
PAK3
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
PIK3CD
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
PIK3CA
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
PIK3CA
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11094073
9891995
|
PIK3CD
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
PIK3R2
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8596638
11733063
|
WASF1
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8307379
21946561
|
PIK3R1
|
VPS13A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
VAV1
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
11331248
|
PIK3R1
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
11331248
|
UTRN
|
PPIA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0808249105
18838687
|
RRBP1
|
PTPRS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PTPRS
|
RAB35
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
RHOA
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18511940
6743311
|
VAV2
|
RHOA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18589439
8990121
|
SRC
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10592173
23027962
|
VAV1
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1531699
1311423
|
SRC
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1531699
1311423
|
SRGAP3
|
WASF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12447388
|
VTI1B
|
STX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
VAV1
|
VAV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
ERBB2
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
MAPK8
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
VAMP7
|
STX6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
19557002
|
EMD
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25910212
34079125
|
LYN
|
FRS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23503679
34079125
|
PTPRF
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
25458010
|
RAB1A
|
RAB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26344197
34079125
|
RHOA
|
RAP2C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
STX4
|
STX10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
34079125
|
VAMP7
|
STX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
19557002
|
PIK3CG
|
PIK3R5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
CDH2
|
CTNNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
PLXNB2
|
TACC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
RHOA
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
8824197
|
CYFIP1
|
WASF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
RHOA
|
TIAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31871319
32203420
|
STX6
|
STX10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
26186194
34079125
|
STX6
|
SCFD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
26186194
34079125
|
EMC7
|
EMC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
26496610
27342126
32439656
26186194
28514442
22119785
|
OSMR
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25241761
11821958
|
SRPRB
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
SRPRB
|
STX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
VTI1B
|
STX10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
STX4
|
STX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25416956
32296183
|
DAAM1
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
EMD
|
SUN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
19933576
30833792
|
OSMR
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10586060
28514442
33961781
|
STX10
|
VTI1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
PAK4
|
RAC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
AAAS
|
NDC1
|
â—¼ CORRELATES
|
|
+
|
0.84
|
0.84
|
CCLE
|
31978347
|
ABI2
|
WASF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
MAP2K7
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
RAC3
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
SRC
|
LYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
22581261
32707033
18070987
9169421
|
SRC
|
MPZL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11751924
16189514
10681522
|
STX4
|
STXBP3
|
â—¼ CORRELATES
|
|
+
|
0.85
|
0.85
|
CCLE
|
31978347
|
DOCK1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17474147
12615911
|
SRC
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12215529
16374509
|
CDH2
|
CTNND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
CYFIP1
|
NCKAP1
|
â—¼ CORRELATES
|
|
+
|
0.86
|
0.86
|
CCLE
|
31978347
|
BAIAP2
|
WASF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
EMD
|
LMNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17620012
34079125
12670476
|
LMNB1
|
LMNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
NCKAP1
|
WASF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
PIK3R2
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ARHGEF7
|
PAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
PIK3R1
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
RAP1GDS1
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
IL6ST
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
PAK2
|
PAK3
|
â—¼ CORRELATES
|
|
+
|
0.87
|
0.87
|
CCLE
|
31978347
|
VAV3
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10523675
32203420
|
VTI1B
|
STX6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
27791468
26186194
28514442
34079125
|
RHOA
|
ITPR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12766172
31871319
|
VAMP7
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
12853575
14993220
|
ARHGEF7
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CYFIP2
|
NCKAP1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
ERBB2
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CYFIP1
|
NCKAP1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
MAP3K1
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
MAP2K4
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
STX6
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
32296183
25416956
26186194
21516116
28514442
34079125
|
PIK3R1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
RAB7A
|
RAB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
26496610
26344197
34079125
|
CYFIP2
|
WASF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
ERBB2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
RAB1A
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
RAC3
|
CIB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11756406
|
CANX
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14681859
2450918
10064069
|
NFKB1
|
B2M
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12480693
2196446
|
SCFD1
|
SEC22B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
WASF1
|
ABI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
24439376
21107423
19363480
28514442
|
RHOA
|
ARHGEF12
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
12220504
15210733
12730235
|
BAIAP2
|
WASF2
|
â—¼ UP_REGULATES
|
✅
|
+
|
3.0
|
0.9
|
ACSN
|
12054568
16702231
9843499
|
BAIAP2
|
WASF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11130076
16713569
|
MAPK8
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
UTRN
|
DAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
20625412
11430795
11430802
|
SRC
|
DAG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11724572
12795607
17474147
|
SRC
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22973453
19704002
21075308
7542762
7797556
19372587
29720121
11940572
17875712
|
ERBB2
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18955552
20937854
15156151
|
ERBB2
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16273093
17496910
|
LYN
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11782428
|
LYN
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9209406
8677749
7539782
|
LYN
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10318860
|
MAP3K11
|
MAP2K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9003778
|
MAPK9
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAPK8
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAP2K4
|
MAPK10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAP2K7
|
MAPK8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAP2K7
|
MAPK9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAP2K7
|
MAPK10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAP3K11
|
MAP3K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7600582
8910292
16253996
|
PIK3R2
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22402981
8596638
11733063
|
PIK3R1
|
PIK3CG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8596638
14665640
11733063
|
SRC
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25814554
22402981
|
PTK2B
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
10679059
12626562
9763606
|
RELA
|
TNFRSF10A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12615723
21243522
|
DAG1
|
UTRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
CYFIP1
|
WASF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
ARHGEF12
|
RHOA
|
â—¼ GTPASE_REACTION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
11094164
|
HLA-B
|
B2M
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
8624811
5220994
|
STX6
|
VTI1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
MAP2K4
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
KRIT1
|
RAP1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
WASF2
|
ABI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
33961781
28514442
17101133
|
RAB1A
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
SRC
|
CTNND1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.93
|
0.93
|
Signor
|
11382764
|
CYFIP2
|
WASF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
RHOA
|
ROCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
STX8
|
VTI1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
SRPRB
|
SRPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
33961781
26344197
26496610
26186194
28514442
|
PIK3CA
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
EMC7
|
EMC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
ARHGEF7
|
PAK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
CYFIP2
|
NCKAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
PIK3CB
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
NCKAP1
|
WASF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
PIK3R1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
20018188
7383613
|
ROCK1
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31871319
14660612
31431478
8816443
21281639
8798490
12773565
|
EMC2
|
EMC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
MAP2K7
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ARHGEF12
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
ABI2
|
CYFIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
B2M
|
HLA-C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CYFIP2
|
WASF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
PIK3CD
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
B2M
|
HLA-B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
ABI2
|
WASF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
PIK3CA
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
SRPR
|
SRPRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
ABI2
|
NCKAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
STX4
|
STXBP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CYFIP1
|
WASF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
CYFIP1
|
NCKAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
EMC2
|
EMC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NCKAP1
|
WASF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NFKB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
PIK3CA
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
SRC
|
TIAM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12810717
19285946
|
SRC
|
VAV3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17686471
8986718
11007481
10395673
9099726
|
SRC
|
VAV3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17998938
11917103
|
VAV3
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10523675
10592173
32203420
|
SEC22B
|
RAB1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
21532587
24917561
20966969
17287728
|
ADAM9
|
ITGAV
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15361064
11162558
|
ERBB2
|
ARHGEF12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
12220504
15210733
12196628
12730235
|
ARHGEF12
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
9789025
17145710
15364580
23405219
32203420
9113980
9641915
20300064
10592173
11373293
12515866
11094164
11149925
|
ARHGEF4
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9789025
10947987
32203420
9113980
9641915
11149925
|
SRC
|
ARHGEF4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18653540
|
PAK2
|
ARHGEF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16374509
17392278
32296183
|
PAK2
|
ARHGEF7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16374509
12226077
16787945
26496610
|
BAIAP2
|
WASF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
26186194
9843499
16702231
11130076
26496610
12054568
16713569
|
SRC
|
CDH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
16371504
15782139
9592087
16492141
9278444
28163245
10502299
|
SRC
|
CLTC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10089883
19289168
12237126
|
CTNNA1
|
IQGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19737400
9694656
10473551
19079338
|
SRC
|
CTNND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17389395
11382764
19138410
20068231
18707149
17194753
23457577
26477567
14996911
17016520
18669648
|
ERBB2
|
CTNND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17496910
22558232
12040186
19568798
14585353
|
CYFIP2
|
WASF1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
4.0
|
1.0
|
ACSN
|
12181570
16212495
16702231
9843499
|
RHOA
|
DAAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
53.0
|
1.0
|
ACSN
|
11226259
11698448
11729192
11739775
11779461
11992112
12194823
12361600
12740575
14657501
14704854
14744429
14747478
15265686
15279786
15618519
15761148
16713974
17127310
17303408
17517963
17660363
17884187
18037882
18256687
18423981
18497258
18590585
18851840
19020754
19366350
19565474
19836308
19853559
20006983
20535745
21178402
22017973
22949611
23732914
24857661
24919149
26885855
26885856
27048821
27066895
7479854
7575488
7641885
8655584
9362522
9660866
9822605
|
RHOA
|
DAAM1
|
â—¼ SHARES_COMPLEX
|
|
|
53.0
|
1.0
|
ACSN
|
11226259
11698448
11729192
11739775
11779461
11992112
12194823
12361600
12740575
14657501
14704854
14744429
14747478
15265686
15279786
15618519
15761148
16713974
17127310
17303408
17517963
17660363
17884187
18037882
18256687
18423981
18497258
18590585
18851840
19020754
19366350
19565474
19836308
19853559
20006983
20535745
21178402
22017973
22949611
23732914
24857661
24919149
26885855
26885856
27048821
27066895
7479854
7575488
7641885
8655584
9362522
9660866
9822605
|
DAAM1
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11779461
25241761
18218625
20810787
19365405
|
SRC
|
DAG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
12795607
18982058
17474147
11724572
|
LYN
|
DAPP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17389395
19901323
10770799
11524430
14688341
10880360
11102801
|
SRC
|
DAPP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17389395
19901323
11524430
10770799
14688341
17570479
10880360
11102801
15494510
|
ITGAV
|
DOCK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10837075
11146654
14697347
15031725
18353785
22035837
22470492
9295024
9763615
|
SRC
|
EMD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
25008017
24609268
19789182
29684168
24365856
17637040
|
ERBB2
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17145710
17496910
11546794
23331499
9756944
16273093
1351056
15680399
11331299
21075308
16843263
|
ERBB2
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16769082
19617202
11940572
12753909
21075308
7542762
|
ERBB2
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17496910
16273093
1334406
16729043
|
SRC
|
GJA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
24508467
19901323
16492141
21856279
10871288
11514593
10679481
15782139
9592087
16189514
30448479
30095367
19284610
26706150
30323740
27280719
9278444
24670366
15350848
16916748
23718910
22342665
15534005
29587860
23596415
|
PIK3CA
|
GOLGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19345670
9918857
19438505
23168613
27795560
31066629
17764812
11027663
|
PIK3R1
|
GOLGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19345670
9918857
19438505
23168613
27795560
31066629
17764812
11027663
|
JAK1
|
IL6ST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8390097
9238703
16051226
11943154
|
OSMR
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10692570
23331499
21071413
10854424
18988627
8999038
9188471
|
IL6ST
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
7896787
23331499
11468294
9388212
21220115
24710148
11742534
23663276
12487370
|
IL6ST
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9013873
|
JAK1
|
INHBA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
MAPK8
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23435430
16469705
15358865
16446428
|
LYN
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8197119
16492764
16720384
7512720
10537111
|
OSMR
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10586060
23331499
15935618
|
JAK1
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10702271
|
JAK1
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9774657
15021914
|
JAK1
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9774657
15021914
7544789
|
RHOA
|
KTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
7787244
11933159
8769096
9822636
8912005
11689693
|
RHOA
|
KTN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12773565
11689693
8769096
11162552
|
LYN
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21780115
15032589
11526404
23109003
22880054
10488096
|
LYN
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18453587
23109003
12495636
17570479
11311138
7529876
10593973
|
LYN
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21780115
29145629
12506011
18453587
11526404
10455108
15032589
23109003
23180781
9334184
15149544
10194437
22880054
11598010
10488096
|
MAP3K1
|
MAP2K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7839144
17143273
11971971
9639556
|
MAP3K1
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
41.0
|
1.0
|
ACSN
|
10086337
10465784
10567412
10811803
10982827
11274345
11447289
11668179
11777939
12040186
12048245
12175651
12419216
12640133
12738796
12782630
14585353
15170913
15567848
15574420
15863030
16102570
16227978
16488589
16582911
16887996
17496910
17496911
17673906
18855897
19449109
19568798
19615955
21102635
21614932
24027568
26552706
7510700
8551221
9379049
9582321
|
MAP3K1
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
83.0
|
1.0
|
Omnipath
|
17145710
15863030
8551221
10811803
11447289
16582911
11777939
18855897
9379049
16472679
12640133
12040186
9305638
26552706
23331499
12048245
10982827
16227978
11668179
23180781
21614932
9808624
12738796
12782630
9889102
9891069
10567412
12175651
18182252
19568798
16102570
9582321
14585353
10521444
17673906
17496910
11242034
10465784
7510700
9712898
11274345
12419216
7992057
7600582
10086337
17276500
15574420
19449109
26192618
19615955
19369195
24027568
10400627
16887996
8910292
12456688
9487126
21102635
15567848
17496911
16488589
15170913
|
MAP3K11
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
18000759
9003778
8702571
11777939
9162092
12040186
11335711
23331499
21614932
15911620
12738796
15735676
23907458
19568798
14585353
16000309
17496910
15328343
10727406
11274345
11053428
17276500
15574420
19151919
18855897
|
MAP2K4
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
17143273
10713157
11489946
7600581
8702918
17145710
13130464
23416355
10748139
8805275
18855897
10791986
9108083
19690332
95141073
18083107
9724739
12788955
9305638
23331499
19534553
15068801
7839144
10958661
21071413
23047924
11062067
21614932
9808624
12738796
15911620
15998799
9891069
11389443
18988627
9733714
11847100
18669648
16153436
10521444
15302099
16282370
11242034
14523011
12709432
26370088
9661668
10499589
7652575
16076903
7992057
16440308
7600582
17192257
9860979
15755722
12133933
16533805
19369195
9312068
9207092
10385525
12354380
12917261
8910292
9487126
9448004
10962008
12624093
11274345
11099046
|
MAP2K4
|
MAPK10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
17143273
11489946
10748139
18408005
18855897
17761173
18083107
8974401
12788955
10715136
23331499
23047924
11062067
21614932
15911620
12738796
11389443
18988627
12624093
11847100
11242034
26370088
16076903
12133933
19651622
12354380
14523011
11274345
|
MAP2K4
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
17143273
7600581
11489946
10748139
18855897
14699111
10791986
17761173
18083107
12788955
9305638
22730327
23331499
19534553
23047924
11062067
21614932
12738796
15998799
11389443
18988627
9733714
11847100
16153436
21900206
11242034
14523011
26370088
10499589
16076903
7992057
7600582
9860979
17192257
15755722
12133933
19369195
9841871
10385525
12354380
9448004
12624093
11274345
11099046
|
MAP3K1
|
MAP2K6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17143273
9639556
19369195
9712898
16728640
|
MAP2K6
|
PAK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15550393
|
MAP3K1
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10465784
11274345
11668179
12048245
12738796
15170913
15592525
17462996
17496911
18641653
18855897
19392652
21133840
21232017
21614932
23850759
24378531
9379049
9582321
|
MAP3K11
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17496910
18000759
15574420
19151919
11777939
18855897
21614932
12738796
11274345
12040186
19568798
10187804
14585353
|
MAP3K1
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
10713157
19392652
18855897
9379049
26696630
17462996
12947395
18641653
23331499
23850759
12048245
11668179
21133840
21614932
21232017
12738796
9582321
24378531
22903704
11242034
10465784
15592525
17110930
26192618
9312068
17496911
11274345
15170913
|
MAP2K7
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
11489946
9362518
18855897
23331499
9890973
11062067
21614932
12738796
11389443
11242024
12624093
11847100
16153436
16076903
17192257
15755722
19369195
19822663
14523011
11274345
|
MAP2K7
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
65.0
|
1.0
|
Omnipath
|
12821118
10713157
11489946
17145710
9362518
13130464
18855897
19690332
95141073
24975362
23331499
7839144
21071413
18362184
11062067
21614932
15911620
12738796
18436711
11389443
10506143
11242024
11847100
18669648
16153436
15725726
25241761
18691976
14523011
25284480
16076903
17192257
11390361
15755722
16533805
19369195
9312068
9207092
9733513
12758252
12624093
15212693
11274345
|
MAP2K7
|
MAPK10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
11489946
9362518
18855897
18083107
10715136
23331499
9890973
11062067
21614932
15911620
12738796
11389443
11242024
12624093
11847100
18691976
16076903
14523011
15212693
11274345
|
MAP4K4
|
MAP3K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9712898
8824585
23331499
|
MAP3K1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12228228
9405400
25241761
10465784
15757900
15299005
14500727
21152872
26538579
|
RHOA
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15659383
25241761
8824197
|
SRC
|
MPZL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10681522
15212693
18578522
11751924
19664994
20068231
18707149
16189514
17016520
18669648
|
NCKAP1
|
WASF1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
4.0
|
1.0
|
ACSN
|
12181570
16212495
16702231
9843499
|
RELA
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16778171
20427719
23362108
16513645
1740105
20596645
16513841
19469019
8454856
21420936
16135789
9417120
|
NFKB1
|
TNFRSF10B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18523266
18599488
19351839
|
NFKB1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16209943
25609649
8428580
12947093
16970925
17072323
2050119
15657065
21270162
11976329
16793322
21544861
22261743
8657102
9824778
11880271
9450761
17962807
21988832
25355951
9722548
18215660
14743216
15799966
10799898
16105840
15218526
8798655
14690596
22139845
22808155
11571291
17072327
16740634
10498867
8255759
8246997
15214841
16846590
15371334
16285893
17072322
17855547
18321863
16493424
7479976
15145317
17561400
20110362
9426183
23687337
12414801
11970949
20154269
20237821
24175631
24634218
34100597
14645533
17982102
21763497
16204234
9437432
20547752
15818410
7628694
|
SRC
|
PAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16374509
12215529
|
SRC
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
12682286
15314172
20861220
18657504
11689445
12431978
25587652
11044445
22266855
11029403
11029009
|
PIK3R3
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8596638
22402981
9415396
11733063
26496610
25814554
|
SRC
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12750372
10592173
17275257
10830300
|
PIK3R3
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8596638
22402981
11733063
25814554
|
PIK3R1
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8596638
25241761
20713702
27107012
11733063
21825134
32814053
26496610
8139559
14729945
10358930
14665640
|
PIK3CD
|
VAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
7691807
7687539
7687428
15187135
10706702
7528218
|
PIK3R1
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9113989
8596638
21827948
12147247
11733063
22020336
24165795
31031754
14665640
|
SRC
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21780115
15032589
11526404
23109003
22880054
10488096
|
SRC
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
9560226
20028775
19919693
15585656
12495636
16713569
31979355
18083107
15105428
15778498
10593973
17389395
25349423
19534553
11149930
12486027
10329689
22581436
19380485
15166227
12526812
12522270
23109003
14963038
8849729
20001213
9556630
18935208
12345678
12231407
17192257
7529876
15695828
15070849
20381867
14739300
19369195
11274221
26866924
10777553
10521452
20521079
|
STX10
|
RAB9A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
18195106
25343031
16885419
19620288
18946081
17488291
8440258
|
STX16
|
RAB9A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
18195106
25343031
16885419
19620288
18946081
17488291
8440258
|
SRC
|
RAP1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
14754902
8755247
11940607
17218263
18434644
10964917
10446041
|
RAP1GDS1
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
9789025
20709748
9113980
9641915
21242305
16189514
11948427
11149925
|
RELA
|
TNFRSF10B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18523266
18599488
19351839
|
VAV1
|
RHOA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10077632
10646608
10679059
10714681
10849438
10898494
11080163
11526404
11698448
11754814
11994416
12094222
12165654
12186560
12616499
12626562
12740575
12885870
12917349
14764585
15169881
16887996
19909365
20189481
22513334
22786724
22952938
25355530
25539813
26552706
8189062
8226994
9438848
|
RHOA
|
ROCK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11698448
11729192
11739775
11992112
12194823
12361600
12740575
14657501
14744429
15761148
17517963
18037882
18423981
20535745
21178402
22949611
24857661
24919149
26885855
27048821
27066895
7479854
9362522
9660866
9822605
|
VAV1
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
10849438
22952938
9695188
12626562
12917349
12165654
25539813
19909365
14757747
18511940
10077632
26552706
12885870
11526404
10898494
25355530
10592173
11698448
10646608
11994416
16397238
20189481
22513334
12616499
10679059
23109003
12740575
11754814
9438848
11080163
10714681
32203420
9601639
14764585
15169881
22786724
12094222
26192618
8189062
8226994
16887996
12186560
|
VAV2
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9789025
32203420
9113980
9641915
10592173
11909943
11149925
|
RHOA
|
ROCK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
17145710
12361600
25010901
23151663
7479854
27048821
22949611
21281639
26885855
8798490
12727213
17673200
11729192
8816443
10592173
11698448
27066895
11739775
11992112
20535745
18423981
24857661
21178402
23109003
9660866
9822605
17517963
14660612
15774750
12740575
14744429
9535835
12773565
15761148
24919149
26192618
9362522
18037882
14657501
12194823
|
SRC
|
VAV2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17686471
8986718
11007481
10395673
9099726
|
SRC
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17686471
8986718
11007481
10395673
9099726
|
SRC
|
WASF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16317717
23354023
|
SRC
|
VAV2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1531699
23118862
23457577
17570479
1311423
|
TNFRSF10A
|
TNFRSF10B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9430228
16319225
|