Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAC3 RXRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0705356104 17947383
AR RACK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17108144 12958311
YWHAZ CAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ENSG00000137843 PAK6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
LRRK2 AHCYL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
HSP90AB1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
AR YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19996220 8009645
RXRA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
AR RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15650026
ARHGEF6 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 16492808
YWHAG ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAE CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
YWHAG CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
NCK1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
NCK2 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12810700 12215529
RXRA CNOT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16778766 5218748
DAPK1 PAK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DAPK1 TPD52L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DCAF7 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAZ DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
NFATC4 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16219765 17194453
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
YWHAZ HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSP90AB1 LIMK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17188549 16641196
HSP90AB1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAZ LIMK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215799 12361576
LIMK1 MAPK14 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16456544 5218304
LRRK2 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
MAPK14 MAP2K6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255949 5219578
MAP2K6 MAPK14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8622669 7535770
MDM2 MDM4 â—¼   COLOCALIZATION 2.0 0.8 intact 17159902 5219425
YWHAQ MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
YWHAB MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
YWHAH MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
YWHAE MDM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16511560 5218386
NCK1 MYLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SYNJ1 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217936 16137687
NCK1 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
RAC1 NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
NCK1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
NFATC4 YWHAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10611249 8005424
YWHAZ PAK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAQ RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
YWHAG RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
YWHAZ TPD52L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12963375 5216659
YWHAB TPD52L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12963375 5216659
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
NCK1 NCK2 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
YWHAQ CBL â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8005785 11697890
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
CBL YWHAB â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
RAC1 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433G TTC28 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CBL 1433E â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11697890 25036637
ESR1 1433E â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
1433E DCAF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 17979178
1433T MYLK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20618440
RAF1 DCAF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16364241 34017080
LRRK1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20144646 19712061
LRRK2 VDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 21370995
PAK4 RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 11756552
LRRK2 YWHAE â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ESR1 1433Z â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 19805454
NCK2 CBL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24287595
RHOJ CDC42 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10967094 31871319
ESR1 SART3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 23403292 31527615
NCK2 TTC28 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VDAC1 VDAC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31536960 22939629 29128334
LRRK2 YWHAG â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
1433G CBL â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11697890 28514442 15324660 33961781
PAK6 1433Z â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 32707033
MDM4 1433Z â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18356162 28514442 16511560
MDM4 1433T â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18356162 17110929 29523541 16511560
ESR1 PSPC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 RXRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9121466 23403292 9717844
MDM4 YWHAQ â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
PAK4 RAC3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
PAK6 1433G â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
PAK6 1433E â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
1433E PAK4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29100370 17979178 32707033
LRRK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
ESR1 MYLK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21182203 25604459 21182205 31527615
LRRK2 PAK6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24510904 26375402 24947832
LIMK2 LIMK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9089416 8980133 33961781
1433Z MYLK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20618440
LRRK2 DDB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31046837 24725412
RAC1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21454543 31046837
CDC42 ENSG00000137843 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
ARHGEF7 CDC42 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
1433T PAK6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32707033 17353931
YWHAG PAK4 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 29100370
PAK4 YWHAG â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5217174 15324660
ESR1 TRIM24 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ARHGEF7 RAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CBL YWHAQ â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
YWHAE YWHAG â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
RAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21217774 16331275
SART3 ANDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15031286 16713569
LIMK1 1433Z â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12323073 12361576
MDM4 1433E â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16511572 18356162 29523541 16227609 16511560
LRRK2 1433E â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20642453 31046837 23075850 24947832 24725412
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
NCK2 RHOV â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 16752908
CBL NCK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
LRRK2 YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MDM4 USP7 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MDM4 YWHAG â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
RAF1 YWHAH â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RAF1 YWHAE â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RAF1 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RXRA TRIM24 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
1433G 1433T â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15324660 17085597 28514442 22863883 20618440
1433Z 1433T â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26496610 28514442 22863883 20618440
1433T 1433E â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 31980649 20936779 21988832 17085597 28514442 17979178 20618440
1433T PAK4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15161933 17353931 28514442 32707033
1433T ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33731348 31527615 11266503
DCAF8 DDB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 33288900 16964240 19966799 31391242 32235678 24500646 16949367 32703400 31257023 28514442 19295130 31155351
MDM2 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897156 17545634 10766163 11178989 16713569 31012223
NCK2 NCK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194 31980649
AR MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PAK6 ANDR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11773441 11278661 16713569 23132866
MDM4 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16511572 22556425 29523541 24190973 16511560 21148311
PAK4 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15324660 17353931 29100370 28514442 32707033
1433E 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26344197 31980649 20936779 21988832 17085597 28514442 31536960 17979178 12507503
1433Z 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31536960 33961781 26344197 26496610 28205554 28628118 28514442 22863883 20618440
1433G LRRK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23075850 28202711 20642453 24947832
1433G RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 10433554 16093354 31980649 17353931 25852190 10620507 11697890 28205554 28628118 8702721 16041367 28514442 32707033 16189514
1433Z RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14688280 16093354 16306228 10887173 9153224 9261098 11697890 15664191 7628630 20052757 10611249 8085158 28628118 7939632 16041367 17979178 12861023 32707033 25852190 10620507 7935795 8601312 9632690 31980649 20679480 19049963 28205554 22222486
1433Z LRRK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20642453 26375402 31046837 23075850 24351927 24947832 24510904
1433Z PAK4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15161933 15324660 17353931 29100370 28514442 32707033
1433E RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16093354 15459208 31980649 25852190 7644510 19608861 11697890 8702721 16041367 17979178 16189514 32707033
CBL 1433T â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8663231 9092538 11697890 16713569 15094368 19380743 11024037
1433T LRRK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20642453 22612223 31046837 23075850 24351927 24947832 24510904 29519959
1433T RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 8663231 7760835 16093354 31980649 17353931 25852190 10620507 7479742 15618521 11697890 10757792 16041367 28514442 32707033
TRIM24 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9115274 19909775 16713569
ARHGEF6 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15649357 15306850 25241761
NCK1 CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 7517397 10829062 10372803 10204582 11494134 24287595 10967110 16503409 9851874
PAK4 CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31871319 26344197 17353931 31478661 11756552 20936779 9822598 29734338 32707033 16189514 26598620
PAK6 CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31980649 20936779 11773441 32707033 16189514
CTTN YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 093880 8009870 20363754
ESR1 NEK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
PAK6 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25714010 26375402 28007610
PAK6 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MDM4 MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26720344 33961781 27621617 26359458 10827196 10629057 24755078 23671280 22902369 22745160 22333590 15604276 20484049 18566590 12370303 30598450 31796886 10218570 19432880 34551723 12483531 29524278 17159902 27777309 12860999 27215386 11606419 18219319 17301054 19683495 25512388 20724842 28628118 16227609 22493164 20473904 25384516 26001071 25825738 22266850 29057323 25809483 25703327 32427989 20705607 10608892 31024344 19619542 21988832 29262653 25659040 29523541 28514442 27617579 29295817 33985974 12393902 16055726 23028042 24813712 22120712 32300648 32075226 21925390 17616658 28205554 23946421 19838211 25105592 12874296 25961923
PAK4 YWHAZ â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
YWHAE RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8005785 11697890
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
RAF1 YWHAQ â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
LRRK2 YWHAZ â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
CDC42 PAK4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MDM2 USP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
YWHAH RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8005785 11697890
MAP2K6 MAPK14 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CDC42 PAK6 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
MDM4 MDM2 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 17159902 5219425
CBL 1433Z â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 11697890 9632690 20618440 9367879
YWHAB RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 19595761 8009093
ANDR MDM2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 17974989 28151478 33332287 26196320 26973243 23132866 12145204 21157430 28708672 27903893 29755129 32801300 26411689 29402932 18332867 15640443
1433Z 1433E â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19766566 31536960 33961781 26344197 31980649 22939629 26496610 20936779 21988832 28514442 22863883 17979178 20618440 16376338
RAF1 MAP2K1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 7014125 19197339
YWHAZ RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 14688280 309620200 8006563
USP7 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6799761 18566590
MAP2K1 RAF1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AHCYL1 AHCYL2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RAF1 YWHAZ â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
MDM2 MDM4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
CDK1 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19652693 18590585 7575488 16565220 17303408 12124778 17570479 17660363 14657031 15279786 15917306 15302935
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
MAPK14 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30644418 24424504 21820033 16282370
CDK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 26573794 12569365 22275373 25704883 17043241 23321516 9725910 24480624 21799006 24424504 28062857 21820033 25950519 28415597 27450452 25691442 21782001
PAK6 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 28007610 24204982 11773441 30217566 11278661 25152898 23132866 16713569 14573606
MDM2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17974989 26411689 27835608 26973243 15640443 12145204
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
CBL ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23175185 12935897 16407834 22588125 14505571
LRRK2 ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21048939
ARHGEF7 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 23175185 12935897 16407834 22588125 14505571
ARHGEF7 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 24792722 16983070 18684957 16492808 9659915 10592173 14557270 11309380
ARHGEF7 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15649357 16983070 9659915 25150978
CAMK2G MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 2160950 18088087 10748018
PAK6 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20936779 11773441 16189514
CDC42 PAK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 10559936 11756552 29734338 15020669 16189514 11340065 15003621 20936779 10934474 11413130 17353931 22653441 11950587 26598620 11248548 9822598 18719708 10613909 10461188
CDK1 MCM4 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
CDK1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10383391 17570479 12032153
CDK1 MCM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17081983 17303408 19793801 15279786 7575488 11454864 16517729 20068231 17116885 17582221 16519687 18669648 18590585 12714602 17660363 17296725 17924679 17102137 16964243
CDK1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15735705
CDK1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25971971 8114697 11684694 17570479 12609978
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
PAK4 LIMK1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10461188 10559936 10613909 11018042 11340065 11413130 11950587 17522712 22154077
PAK4 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22154077 28007610 11413130 10559936 17522712 11018042 11950587 10613909 11340065 16641196 10461188
MAPK14 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15187187 18039929 12738796 11274345 12697810
RAF1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 143.0 1.0 Omnipath 10757792 18337766 18799465 15342917 23728975 26496610 15866172 17053865 11242034 9351825 9677429 8157000 7992057 11948414 11604401 16129686 10677502 12695496 19197339 7565670 12750173 7936666 1326789 19219045 23331499 18556463 10976102 18988627 15485920 15175348 18691976 16407412 10409742 9311917 17192257 7898932 8621729 23934108 11684694 21336309 7624324 12920017 11948406 15466214 11042690 12907640 9032297 27169363 12876277 8933152 8223433 8248196 8131746 12594221 10969079 10567369 17979178 17724343 24746704 19058874 10958680 8090753 21071413 7731720 7873542 1330321 8503013 16093354 19541618 8394352 15466476 25155755 11136732 9069260 94178255 8607979 10327068 10359597 8039496 20212043
RAC1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
MAP2K6 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 96.0 1.0 Omnipath 10480932 19901323 17081983 7914033 9362518 18767875 17322306 8622669 18855897 16342939 16497976 15592455 8974401 7997261 15735649 18291705 23331499 8626699 21071413 16083285 21614932 18452278 12738796 20068231 9808624 11727828 16189514 18988627 17255949 9790884 16153436 18669648 26538579 14970210 16282370 11242034 18691976 18088087 11304531 15972258 10781613 17192257 18586681 10734320 20551513 19651622 15212693 7592586 16157584 21402774 9582275 15674326 9528766 7693711 12758252 11309380 7750576 17255097 17016520 15659558 11274345 15735648
MAP2K6 PAK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15550393
MAPK14 PAK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15550393
MAPK14 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 15649893 16648474 11997522 10747897 18347059 17255949 11274345 12697810
USP7 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 17936559 26460617 15916963 24462112 22056774 18566590 20816748 16402859 20713061 16943424 17380154 29236775 16082221 26238070 34799561 16845383 16474402 28406480 27452404 28196907
PAK6 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 11960368 11923280 18467333 22349818 23132866 11504915 11715018 28196907
MDM2 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 17145710 10218570 17616658 16511560 22266850 12874296 21925390 25825738 21988832 25512388 16227609 22493164 22902369 25659040 18219319 12963717 15604276 18566590 12370303 19838211 26359458 27617579 25809483 34551723 10608892 23028042 22120712 25703327 12860999 32300648 16055726 24813712 17301054 12483531 23671280 17159902 27621617 25105592 20484049 20724842 27215386 10827196 26001071 11606419 23946421 19683495 20705607 24755078 25384516 20473904 12393902
USP7 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20713061 35044719 18566590 15916963 16082221
PAK6 PACSIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24204982 22371566 23918399
RHOD PAK6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11784792 28486133 22665057 31871319 17916560
PAK6 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19165420 23162742 18465753 25632266
RAF1 YWHAB â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 YWHAB â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
YWHAH RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12801936 11697890 8702721 17979178
YWHAQ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 14688280 7760835 17353931 16041367 11697890
YWHAZ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 17145710 7939632 7935795 16306228 9153224 20052757 8085158 8601312 16041367 7628630 11697890 9632690 25852190 9261098 16093354 12861023 15664191 22222486 19049963 10620507 17979178 10611249 14688280 10887173 20679480 12360521
RAF1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17353931 11697890 8702721 10433554 16189514 15664191
RAF1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 17145710 7939632 7935795 16306228 9153224 20052757 8085158 8601312 16041367 7628630 11697890 9632690 25852190 9261098 16093354 12861023 15664191 22222486 19049963 10620507 17979178 10611249 14688280 10887173 20679480 12360521
RAF1 YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19608861 16093354 16041367 11697890 8702721 16189514 25852190 7644510 15459208 17979178
RAF1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 14688280 7760835 17353931 16041367 11697890
RAF1 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 8085158 12620389 16093354 19595761 7882972 16041367 24255178 11697890 7935795 8702721 10848612 16189514 25852190 7644510 12360521 10620507
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAB YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17085597 12657644 12426317 15071501
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAG YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178
YWHAE YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAG YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17085597 21827211 12426317 15324660 15071501 12657644
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501