Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MAPK9 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14673001 17555943
PDGFRB CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731806 17620338
FYN CBL â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 5220480 7642581
LCP2 CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6548125 9716598
YES1 CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8981370 20489731
CBL ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
FYN CBL â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL FYN â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
CBL MET â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5215187 11894096
CBL FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CIB1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16061695
IRS1 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
AREG EGFR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 20430953 23010081
PTK2 EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19948216 10655584
NCK2 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LZTS2 PAK5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RHOU PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217345 15556869
TCP10L PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK11 PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PAK1 GIT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218539 16628223
PAK3 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
PAK1 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PAK1 CTTN â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6541884 18344974
ARHGEF7 PAK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TRIP6 HOXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HOXA1 SLIT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PDGFRB NCK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11027258 6731249
CPSF7 NCK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ABI2 NCK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NCK2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NCK2 TRIP6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NCK2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 11557983
NCK2 EFNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 11557983
NCK2 CD3E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7213612 17617578
NCK2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 11557983
RHOU NCK2 â—¼   COLOCALIZATION 2.0 0.8 intact 15350535 7219187
ABI3 EIF3H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
JUN AREG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22570239 20308529
PAK2 YES1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
ABI1 YES1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
YES1 PDGFRB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7685273 6730440
YES1 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 32296183 35044719
SRC LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
PAK3 LCP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8824201 8798379
LCP2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6546918 15929943
LCP2 NCK1 â—¼   PROXIMITY 2.0 0.8 intact 20562827 7995037
PAK5 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11756552 16189514
NCK1 NR5A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NR5A1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
VEGFA PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15026417 9182576
PDGFRB BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
PDGFRB NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730458 7692233
ABL2 PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19275932
PDGFRB GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14973141
PDGFB BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
JUN PDGFB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10506481 9488709
PDGFB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15845350 12753909
KDR FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
KDR PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15026417 9182576
TCF4 KDR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21722264 19029143
FYB1 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYB1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9207119 5221556
DOCK1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PKD1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABI1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
WIPF1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
WASL FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11340081 16525419
ABL2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ASAP1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PAK2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
FYN MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
FYN WAS â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216858 14707117
PEAK1 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0914776107 20534451
PTK2 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221628 9285683
EFS BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BCAR1 PEAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0914776107 20534451
BCAR1 DOCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12615911
UBC JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
JUN MAPK9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
JUN MAPK10 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18793328 10871633
JUN PAK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17182846 23818969
MAPK9 JUN â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19527717 7148309
JUN MAPK10 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19527717 7148309
WASF1 SORBS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213352 11130076
CHUK IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12351658
DCC RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
NCK1 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
KCTD17 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAC1 CHN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218533 16628218
RAC1 PAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7215301 19264842
RAC1 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
PAK3 RAC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
RAC1 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
RAC1 CHN2 â—¼   COLOCALIZATION 2.0 0.8 intact 5218533 16628218
RAC1 CHN2 â—¼   PROXIMITY 2.0 0.8 intact 5218533 16628218
NCK1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
RAC1 CYFIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9417078 16189514
RAC1 NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
ASAP1 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
WIPF1 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216188 12620186
PAK3 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8824201 8798379
WASL NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11340081 16525419
WAS NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220415 7565724
DOCK1 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS2 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCK1 RHOU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217345 15556869
NCK1 EFS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCK1 ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCK1 DOK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211702 10428862
NCK1 MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
WAS NCK1 â—¼   COLOCALIZATION 2.0 0.8 intact 5220415 7565724
NCK1 PAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11278553
NCK1 MAP4K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9135144 10805734
SOS2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
UBC SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6504434 17936276
WASL SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
MAP4K1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17094785 7033811
SRC EFS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
SRC ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
SRC SHB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12464388 15026417
LNX1 SRC â—¼   COLOCALIZATION 2.0 0.8 intact 6504434 17936276
SRC RHOU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20547754
SRC DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21849478 26323693
CBLB ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
SPRY2 CBLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11053437
CBLB MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CD4 CD3E â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
PAK3 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PAK3 ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9726964
FOSB CDK5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11268215 16242410
PAK2 SORBS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
CTTN PAK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6541884 18344974
PAK2 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12453877 18344974
GIT2 ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218539 16628223
WASL PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
MET PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521801 16782899
PTK2 SHB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15026417 9182576
PTK2 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17893324 22952866
PTK2 ASAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12058076
ASAP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
WASL DOCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
LNX1 KCTD17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SRMS DOK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 8433682 23822091
ABI1 SOCS7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
ABI1 WASF2 â—¼   COLOCALIZATION 2.0 0.8 intact 17101133 5219329
WIPF1 WASL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218469 16582881
WASL DCC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
WASL NPHS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11340081 16525419
WASL CTTN â—¼   COLOCALIZATION 2.0 0.8 intact 6541884 18344974
SOS1 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707404
GAB1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707404
WIPF1 WAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9405671 5221801
ABI3 WAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PTPN12 WAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216858 14707117
PTPN12 GIT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16317044
WASF2 ABI3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17101133 5219329
CEP44 MAPK9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CEP44 ABI3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ABI3 KIAA0408 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PAK1 RHOU â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
NCK1 NCK2 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
NCK2 SHD â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
NCK2 PBX4 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
KIT CBL â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 8950973 16780420 25737303 15315962
PTPN12 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 28065597
FYN EFS â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32296183 25416956 12471123
WASF1 RAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31871319 9843499 19363480
NCK1 PAK2 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
ARPC4 WAS â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
NCK2 ZBTB42 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
BCAR1 FYN â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
NCK1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 8662998 5221064
DOK2 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10508618
SOCS7 NCK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 33961781
NCK1 NHSL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 33961781
NHSL2 WASF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NHSL2 WASF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FYN FYB1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 9207119 5221556
FYN ASAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 16636290
PAK4 RAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31871319 11756552
CPNE5 NCK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EFS NCK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 26871637
NCK1 SOS2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 33961781
NCK1 ASAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 16636290
NCK1 ABI2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26871637
EFS SRC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 8647432
NTRK3 CXCR4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
WASF3 ABI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ABI2 WASL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 26344197
WASF2 ABI3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17101133
NCK1 WASL â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
NCK1 SOS1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
LCP2 NCK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
NCK2 WASF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
LNX1 UBC â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
YES1 ZC2HC1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
CYFIP1 WASF3 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
NCK2 ZBTB12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
MAP4K1 NCK1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
NCK2 CBL â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 24287595 33961781 26186194
EGFR EPHA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24797263 15657067
LCP2 NCK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 26871637
NCK2 ASAP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NCK2 TNIK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 32640226
NCK2 WASF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NCK2 MINK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 32640226
NCK2 PEAK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NCK2 WASF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NCK2 SHB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NCK2 WIPF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NCK2 TTC28 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NCK2 ABL2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NCK2 LZTR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
BCAR1 NCK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22974441 12135674
KIT CBLB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12177062 15315962
CASP1 GAB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FAM53C NCK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
NCK1 WAS â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
PTK2 YES1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CBL LCP2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
SRC CBL â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6538879 18273061
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
NCK2 SOS1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10026169 16713569
NCK2 ABI1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 16713569 33961781 26186194 11557983
ABL2 NCK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17474147 25241761 33961781
CBLB NCK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16503409 16189514 25218436
TRIP6 SRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 16713569 14688263
SRC LNX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17936276
SRC DOK2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15831486 10428862
NCK2 ZC2HC1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
NCK2 TMEM121 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
ABI1 WASL â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ABI2 WASF2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EPHA7 EPHA2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22036564 33961781
NCK2 ILK â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 10022929
KHDRBS1 FYN â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 8374603 22641034
NCK1 RHOU â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 31871319 15556869
EFNB1 SRC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 8878483
SRC DOK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11071635 22974441
PAK4 PAK6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781 26186194
PAK3 RAC1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
HNRNPK KHDRBS1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
KHDRBS1 NCK1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CBL EPHA2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MET CBL â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 6538879 18273061
SPRY2 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 16893902 6169676
MET CBL â—¼   UBIQUITINATION ✅ 0.86 0.86 mint 11894096 5215187
SNW1 CPSF7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34133714 20467437
DOCK1 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17474147 12615911
SRC PAK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16374509 12215529
NCK2 RHOU â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
MAPK9 JUN â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 9405416
EGFR NTRK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
EGFR WASL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
EGFR WASF3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
CBLB NCK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 16189514 25416956 16713569 33961781 26186194 21516116 26871637
NCK2 WASF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 26186194
NCK2 WASL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 33961781 26186194 26871637
NCK2 NTRK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12074588 16713569
NCK2 NHSL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 26186194
NHSL2 ABI1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
NHSL2 ABI2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
SRC KIT â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24728074 12878163 12444928
ABI1 ABI2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 26496610
ABI2 CEP44 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
ABI2 ABL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
ABI2 WASF3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
SRPK1 SRPK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32707033 21157427 33961781
LCP2 NCK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ARPC4 WASL â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HOXA1 SPRY2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
ARHGEF7 PAK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
WASL WIPF3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
NCK2 SCX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
NCK2 ZNF526 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
NCK2 RBBP8NL â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
MAGEA6 NCK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
ARHGEF7 RAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
LCP2 CBL â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10477741 10204582 9716598 19635790
DOK2 NCK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
NCK2 DOCK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 11240126
NCK1 LCP2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 7995037 20562827
NCK1 LCP2 â—¼   PROXIMITY ✅ 0.88 0.88 mint 7995037 20562827
NTRK2 FYN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9648856 16713569
BCAR1 TRIP6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11782456 16713569 14688263
WASF1 ABI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31980649 26496610 27173435 15048123 26344197
TNIK NCK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17474147 33961781 32640226 10521462
BLNK NCK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11487585 25241761 9697839
PKN2 NCK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8910519 10026169
SOCS7 NCK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 9344857
MINK1 NCK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 15469942
NCK1 GIT2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 31980649
NCK1 WIPF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26496610
CD4 CXCR4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10816381 15660419 14592831
PAK2 GIT2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 26496610
GAB1 MET â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
SLIT2 ROBO1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10102268 17848514
BCAR1 PTPN12 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ASAP1 CTTN â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CBL NCK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EGFR NCK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EGFR NCK2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
FYN WAS â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
FYN KHDRBS1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PDGFRB SRC â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
EGFR MET â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
NCK2 PRR20C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
NCK2 PRR20D â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
ABL2 EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 16273093 25402006 31980649
CBLB EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24797263 11375397 20308550 19531499 33848699 10635327 30515972 18271526 28572092 10086340 16729043 31959764 16702950 15657067
EGFR PAK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 24658140 12522133 25402006
EGFR DOK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
EGFR LCP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
PAK1 RHOU â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14521508 26598620 18086875 15350535 31871319 15556869
NCK2 ARAP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
NCK2 ABI2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 29892012 16189514 25416956 32296183 16713569 33961781 26186194 26871637
NCK2 PKN2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16752908 10026169 16713569
NCK2 NCK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 31980649 26186194
NCK2 GIT2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194
SRC FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 19711372 9169421 33961781 16966330
EPHA8 FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 10498895
ABI1 NCK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 11557983 11418237
DOK1 NCK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12087092 22974441 11551902
PAK2 NCK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 33961781 11160719 16374509
WASL WIPF3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 23414517
CBL UBC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
NCK2 SF3A2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KDR SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
DOCK1 RAC1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EGFR GAB1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CBL SORBS1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
NCK1 PDGFRB â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
KHDRBS1 SRC â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EIF3H NCK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
NCK2 VPS37B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BCAR1 PTK2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PAK4 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23642861 11950587 11278822
EGFR CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27059931 7657591 8665853 27903975 15107835 24797263 28791635 9756944 23799367 23175185 28198003 12734385 14505571 20940296 19155296 10635327 15117950 22833562 29629558 12061819 8662998 10086340 33762435 11994282 20877636 32714745 25005938 31182136 19578043 7782294 24714105 10799548 23158001 26055326 33617900 23153581 15210722 25872741 15657067 19947936 10428778 18508924 16969069 17971399 15962011 19531499 25521828 23774213 22976291 31959764 22591401 18255265 15735736 16713569 20562913 17880946 16914641 9890970 22394513 16729043 32114396 17995934 17182860 18319245 18271526 17545148 15383614 25140053 32377695 15465819 33627783 8798643 25754235 15282549 26177020 22266821 16923119 17242169 30544639 12604776 11239464 9130710 19225046 11370743 21772844 16105874 18273061 7592693 23897813 17486068 16246327 23457600 32904620 12803489 31120930 15668240 22203672 23418353 20124286 28541302 33323455 10092522 14627991 15677445 15159412 20308550 16849543 12593795 19836242 9121472 19713535 18316398 11408594
SRC CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29899407 17094785 16713569 18273061 7782294 12941616 10829062 31120930 15135048 17141222 18996392 8635998 11994282 22203672 19861161 16636290
NCK1 CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503409 10204582 24287595 11494134 7517397 10967110 10829062 10372803 33961781 9851874
CBL MET â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11894096 25241761 18273061 19433454 21222362 19450681 21163258 16397241 17533376 15123609
IRS1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10854852 19546233
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
SOS2 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24797263 31980649 23956138 19531499 24658140 25402006 18271526 31959764 10675333
NCK2 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 16713569 22973453 24658140 10026169 1333047 9737977 25402006 9843575
NCK1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 9362449 24658140 10026169 8662998 16273093 25402006 1333047
EGFR MET â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20624308 24189400 21918175 24362532 10722725 23866081 26551075
EGFR AREG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 28988771 10085134 8663535
EGFR GAB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23066441 31980649 10913131 9890893 24658140 10648629 21278788 25402006 10734310 18271526 19401591 11432805
EGFR PTPN12 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 21376233 7542744 7541030
YES1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 22430206 11160627
EGFR BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17145710 17570479 15951569
FAM53C MEOX2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NCK2 TXK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NCK2 PDGFB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 7692233 9739761
CD3E NCK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 16713569 17617578 12110186
RHOU NCK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15350535 31871319 16752908 18086875
EFNB1 NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11557983 16713569 16636066
JUN IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15699140 25567680 28100679
YES1 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16374509
FYB1 LCP2 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 9207119 5221556
SOS1 LCP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11390650 10021361 10224278
LCP2 FYB1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 9207119 5221556
LCP2 NCK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20562827 16189514 15929943 31467278 21725281 22267732 10229072 15388330
LCP2 WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10747096 16189514
SRC VEGFA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
PDGFRB PTPN12 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 12614164 0265574 8312067
PDGFRB SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PDGFB SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PDGFB NCK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 7692233 9739761
SRC KDR â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
KDR PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24043698 22264731 29435030
REL CD40LG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11160303
FYN DCC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
SRC BCAR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 604342200 7033822 17038317
PTPN12 KIT â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 12614164 0265574 8312067
KIT SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8950973 16129412 10377264
WASF1 ABI2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24439376 21107423 33961781 19363480
DOCK1 RAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15723800 15247908 12134158 9808620 31871319 25468898 26344197
PAK2 RAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9535855 22705156 20696164 20936779 19264842 32707033 31871319
RAC1 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18426980 18423204
CBLB NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16503409 16189514
SRC DCC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
ASAP1 SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17474147 9819391 16636290
SRC MET â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24034250 20624308 9837958 24728074
SPRY2 SRC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
SRC EFNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8878483 16189514 22279592
SRC CHN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17560670
PAK3 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26490115 29152154 16854367
NET1 DCC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26190107 12810718 9950216 20434207 19721007
WASL WIPF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16055720 33961781 23414517 22939629
ZBTB7B CD8A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19062319 17296789 17878336
MET CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11439336
SLIT1 ROBO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21600986 30547091
EGFR SOS2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
NCK2 NHSL2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NCK2 PAK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
EGFR SOS1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
BCAR1 SRC â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CBL MET â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
ABI1 CYFIP1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
NCK2 NPAS2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PAK2 RAC1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CYFIP1 WASF2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ARHGEF7 GIT2 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
PRR20C PRR20D â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CBL FYN â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
DOK2 NCK1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 11689432 16189514 10428862
WASF2 ABI2 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 28514442 17101133 33961781
PTK2 SRC â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
NCK1 PAK1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
NCK2 PAK1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
ABI1 WASF2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
NCK2 PAK2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 32296183 33961781 26186194
NCK2 EFNB1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 16189514 16713569 11557983
SF3A2 SNW1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
KDR NCK2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ABI1 WASF1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
FYN YES1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ARHGEF7 PAK3 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
PAK1 ARHGEF7 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218539 16628223
PAK1 PAK2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32707033 23455922 31980649
PAK1 GIT2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 11157752 31980649 16628223 25852190
WIPF2 NCK2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 12213210 33961781 26186194
SOS1 FYN â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 17474147 16713569 9856337
JUN FOSB â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 29020630 33961781 25609649
ABI1 SOS1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10499589 15289329
MET GAB1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10871282 10913131 10995442 10734310 9242692
WAS WIPF1 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
WASL WIPF1 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
WASL WIPF2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
CBLB EGFR â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
EGFR CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16729043 5218694
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
SOS1 EGFR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24797263 16713569 26005835 9447973 23956138 19531499 7510700 20473329 19289468 25754235 18271526 31959764 10675333 8621459
PAK1 NCK1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11278241 10805734 8824201 11157752 10026169 10330411 10372803 33961781 9851874 11557983 15784622
NCK2 DOK1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16713569 33961781 26186194 9737977
NCK2 WIPF1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 32296183 33961781 26186194
SKAP2 FYN â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32707033 16189514 16713569 12893833 31413325 29568343 9837776
RAC1 PAK3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11478794 25301945 11862216
NCK1 SOS1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 8810325 17474147 10026169 10206341 33961781 7862111 32203420
WASF2 ABI1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17101133 31980649 26496610 16055720 15048123 26344197
JUN MAPK10 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
FYN CBL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17094785 8900205 15190072 9890970 25814554 8995358 12244174 10829062 12941616 9311917 12231245 16503409 9677430 8662998 119942 9535867 10092522 15208330 7642581 15556646 16713569 8621719 10629042 7782294 8626543 10799548 11239464
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
NCK2 PAK1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 25416956 31980649 16713569 30886144 10026169 33961781 26186194 11557983 23455922
BCAR1 FYN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10739664 32296183 9360983 16713569 17474147 31413325 9188452
SRC BCAR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10739664 10085298 10542110 21034468 17129785 17038317 11514617 10487518 16849545 12972425 12615911 15020686 12397603
NCK1 CD3E â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 18955169 17617578 12110186
ROBO1 SLIT2 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
CBLB UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
ABI2 CYFIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
JUN MAPK9 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
KDR VEGFA â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
ARHGEF7 PAK1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
ABI2 WASF1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
PAK1 RAC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 24625804 19327867 15143066 9535855 17245428 11134022 15673687 15289329 16492808 16551621 21029865 16678097 19596003 26175416 17389360 31871319 24056087 25843002 25150978 12879077 15212766 19693014 11030651 16630611 20810653 8107774 11130076 25468898 29615491 19732720 19270716 21474670 10706722 19277120 10802735 21167153 24172987 21454543 15548653 16002993 12650940 18426980 19961560 11950930 24792722 15688026 7744004 20936779 25819133 15075243 22581261
WASL NCK1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 11340081 17474147 26496610 16595635 33961781 26871637
WIPF1 NCK1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16189514 10878810 9694849 26496610 33961781 12620186
WASL WIPF1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12437929 28514442 25416956 16582881 11331876 16055720 33961781 12372256 23414517 10087612
CBL SPRY2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CYFIP1 WASF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BAD WASF1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10531306 10760476 10826997 10949026 11078441 11342610 12107820 12175651 12444011 12767520 12931191 16931767 19030972 19641503 20399103 21540285 22039431 7130182 9346240
BAD WASF1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10531306 10760476 10826997 10949026 11078441 11342610 12107820 12175651 12444011 12767520 12931191 16931767 19030972 19641503 20399103 21540285 22039431 7130182 9346240
PAK1 BAD â—¼   ENZYMATIC_REACTION ✅ 39.0 1.0 ACSN 10230394 10461188 10467124 10511705 10558990 10559936 10611223 10613909 10661401 10837486 11018042 11062502 11121431 11340065 11385609 11413130 11493700 11907067 11950587 12054568 12885870 12954615 14749719 14764585 15157156 15229651 15280015 15536084 15713627 16293614 16702231 17270021 17522712 22154077 8625410 8929531 9346240 9381178 9843499
PAK5 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 28007610 10880354 15226424 10521512 15972258 23162742 9381178 12897128 20567954 16403219 15037618 10837486
PAK1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 27121078 20166139 22096607 9346240 18823547 11493700 9381178 23650610 15280015 10230394 10558990 8929531 25225063 18669648 10837486 10611223 23109003 12954615 10949026 16413544 19465939 18707149 15784622 17270021
BCAR1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
KIT CBL â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11994499 16780420 12444928 17904548
BCAR1 CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
ABI1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17395426 18594017
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
FYN CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 97.0 1.0 Omnipath 9525940 7642581 8626543 7782294 15208330 16503409 16713569 10829062 10799548 10934191 8900205 8551236 8662998 8995358 19734451 12604776 9890970 10592173 17570479 10629042 17094785 10092522 11997497 12522270 15556646 12244174 8621719 9102067 22880054 9311917 11239464 19904769 11994282 12941616 9535867 25814554 12231245 15190072
SPRY2 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 21596750 15004239 16479008 18273061 11053437 16893902 15962011 12593796 17974561 12234920 12593795 17255109 20461437 12815057 11983899 20877636 20124286 20622121 16246327
ARHGEF7 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 23175185 12935897 16407834 22588125 14505571
YES1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10092522 11994282 11997497 12522270 9525940 12604776 9890970 9102067 10829062 10799548 11239464 10934191
SORBS1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15128873 9447983 17548467 12504111 12765336 11001060
CBL KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9092574 17904548 25737303 8950973 15315962 17635922 10514377
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL SORBS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12475393 15128873 20886612
CBL ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23175185 12935897 16407834 22588125 14505571
CBL MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16397241 15123609 23331499 25241761 21222362 11894096 18672314 21163258 19450681 18273061 35309168 17533376 19433454 17635922 10514377
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
CAMK2G EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 3138233 10347170 16799092 1309762 7805884 7505275 92065884 15302935
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
CBLB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 19531499 11375397 10086340 12577067 10542134 17635922 10514377
MAPK11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15187187 18039929 12738796 16932740 11274345
AREG EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 23762360 21071413 10209155 10085134 29045902 2466334 20513444 16713569
EGFR SOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23956138 19531499 18271526 24658140 10675333 25402006 24797263
EGFR GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 19901323 15231819 16497976 25402006 17389395 20068231 23066441 11432805 9658397 19509291 18669648 10978177 10753869 10734310 11896055 18271526 24658140 10648629 11779868 31980649 15212693 9890893 17016520
EGFR SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9544989 19531499 9447973 16713569 12577067
EGFR NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 1333047 23331499 10026169 9737977 24658140 16713569 25402006 9843575 1333046
EGFR PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16713569 16919435 25402006 10806474 29435030 20473329 7657702 19339212 17496910 15657067 24658140 19625610 7529872 20802513 31980649 10545505 24043698 15951569
EGFR NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1333047 23331499 31980649 10026169 16273093 9362449 8662998 24658140 25402006 15951569 9843575
SRC EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24457997 28957431 26788993
EFNA3 EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12907451 24003208 15114347 11114742 933086312907451 9330863
MAPK10 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 53.0 1.0 Omnipath 17081983 20166139 18767875 17322306 20230923 19413330 11231586 19664995 19415658 15302935 16083285 20068231 18452278 18669648 18691976 11259409 17287340 19651622 15212693 17924679 19664994 16964243 10329716 18212344
SRC HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7516469 17178840 24642125 12052863 7592945 16854432 16713569 21184736
HNRNPK KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21988832 22365833 31413325 16713569 12370808
LCP2 PAK1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
SOS1 PAK1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
PAK1 CTTN â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 12453877 16854367 9683637 24859002 20444238
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
NCK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 10805734 11278241 10026169 23109003 11096073 10330411 8798379 11278553 16490784 11157752 15784622 9024622 9755165 8824201
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
NCK2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 10026169 25416956 10592173 31515488 11557983 32296183 16713569
CDK5 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20058876 17114649 12176333 12950086 19298660 19664994 12176334 15542607 19413330 23537649 19036346 19664995 21825040 11604394
RHOU PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18086875 15350535 11459829 14521508 15556869
PAK1 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22521536 25738875 27642646 17420447
PAK1 NET1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18509476 15684429
PAK1 ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 20936779 16101281 11096073 10330411 11157752 16628223 9726964 16492808 9659915 10592173 16407834 17392278 29997244 32814053 25472536 23455922
PAK1 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15561713
PAK1 NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 10026169 25416956 10592173 31515488 11557983 32296183 16713569
PAK1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 30562756 24859002 12453877 18344974 29152154 21079800 26490115 27135389 16854367 20444238
PDGFRB NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 10026169 9737977 11027258 16713569 16636066
NTRK2 NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12074588 16713569
NCK2 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10592173 11950595 16713569
IL10 NFKBID â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10433356 10542212 10623821 10925299 11207245 11438547 11875494 12193690 12811837 12818165 14607900 15282297 15579430 15749903 15833879 16200688 16424049 16713974 17404308 17485448 20184663 20435894 20547845 21115385 21191065 21220452 23124025 23508573 24378531 26755705 9834059
SRC TXK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11353545
FYN TXK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12081135 11353545
TXK LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12817019 9047237 15388330 10660534 8892604 12640123 8702662
YES1 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11369622 12558988 16293639 12590707 25868388 15728464 25416956 32296183 10753828 23397142
YES1 KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11071635
YES1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18479465
RAC1 LCP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17540168 11278486 11804587 12670394
LCP2 PAK2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
FYN LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648627 9047237
MAP4K1 LCP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21949020 17353368 28107427 22105350 11487585
VEGFA NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFA KDR â—¼   PHYSICAL_INTERACTION 58.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFA KDR â—¼   PROTEIN_INTERACTION 58.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFA NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFA KDR â—¼   ENZYMATIC_REACTION ✅ 58.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFA FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
JUN VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9256279 11204570 11353786 23274526 11678207 17341624 20015448 8910439 16328781 11731421 15039660 19553068 20432243 7887961 12163680 10885623 11281649 14602779 18294451 15277220
VEGFA KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 22897854 15637071 1417831 23374253 12716911 18325345 16763549 31023826 8356051 16901919 24023956 17658244 20145116 8621427 11333271 16423422 22174934 16633338 11181169 27005951 9556609 8631822 17318185 12189247 31932617 23583373 20660291 19818105 24966171 21596751
PDGFB PDGFRB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFB PDGFRB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFD PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 1520781114514730 23331499 15207811 21098708 14514732 15207812 28267575
PDGFB PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9739761 20577048 30150707 16189514 15207812 28267575 7679113 11297552 15207811 20534510 17981115 10806482 285049611903042 11903042 11331882 2850496
PDGFRB NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1333047 23331499 10026169 9362449 16189514 16636066
PDGFRB FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 1696179 7685273 7687537 16713569 1661130 9425276
PDGFRB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15489898 18315570 16189514 9010229 2173144
PDGFRB PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10806474 20802513 16713569
PDGFB SRC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 7685273 9488729 10508235 9739761
KDR NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
KDR NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
KDR FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SRC KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19050761 18662404 18194650 10749680 12509223 18377662 10455194 16966330 12214271
FYN FYB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 10229084 10570256 7504057 20661443 25814554 9207119 10497204 24769494 26246585 16713569 23979596 33431658 10409671 17474147 30305305 9748251
FYN DOCK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
DAB1 FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 17350651 23052211 23506116 16529723
FYN ARHGAP32 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 10591186 10648627 12218089 12731048 12788081 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
NCK1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
CBLB FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15208330 16503409 32296183 25814554 8083187
NTRK2 FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 16713569 9648856
FYN WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 18083107 25709608 7565724 8805332 10224664 18088087 19690332 12431372 12235133 16713569 15592455 10532312 14707117
FYN PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 11369622 12558988 15494733 20151426 12590707 16293639 7505391 15728464 11278857 16713569 10753828 15494732 10085136 15494734
FYN NPHS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19179337 16543952 21982880 15634346 15579503 10504499 16713569 18212058 12846735 12668668 18256598
FYN KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9038210 9799234 12374739
FYN CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 24872417 19901323 9038181 10896159 18691976 20506281 29063113 20068231 16497976 19413330 14757045 12372285
FYN DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15557120 21849478
FYN SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17474147 16713569 9856337
FYN CHN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17560670
FYN ARHGAP32 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12857875 12788081
FYN DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11489946 16537894 11841937 11825908 15345598
FYN BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17129785 9188452 9020138 10739664 31413325 16713569 11181827 9360983 17474147
BCAR1 DOCK1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11146654 12094222 12432077 14697347 15308668 16000375 16076871 18835194 22464172 9808620
BCAR1 DOCK1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11146654 12094222 12432077 14697347 15308668 16000375 16076871 18835194 22464172 9808620
SRC BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 19901323 24962474 11514617 8670206 15316024 20927395 8070403 17389395 12480533 22710723 30422386 25976166 17570479 21963850 12972425 20103658 17129785 10487518 15817476 21301050 10739664 17038317 21765460 17016520 12397603 15212693 15020686 10542110 23457577 10085298 12615911 15272013 21034468 11604500
FGFR1 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11019781 12601080
PTPN12 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9920935 8887669 11432829 12714323 9748319 9285683
PTK2 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 8649427 7479864 12135674 15673687 8810278 9038154 8670206 9285683 11604500 11119718 12480533 24939893 8621540 11577104 9360968 9148935 10592173 12119061 12972425 9360983 10092764 21855630 10753828 11839772 18233957 10545505 12615911 8662921 11514617
CHUK AXIN1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11955436 11967263 12051714 12799363 23430059 7542250 8666229
CBLB KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15315962 12177062 17635922 10514377
SRC KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12878163 7520444 10523831
KIT DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11071635 11825908
JUN TCF4 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 10391247 11274345 11929833 11955436 11967263 12051714 15001769 15082531 15377999 15576399 15766563 15768032 15806138 16007074 16039586 16169192 16510874 16940750 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19020303 19619488 19623618 19751508 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22270359 22290435 22699938 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN TCF4 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 10391247 11274345 11929833 11955436 11967263 12051714 15001769 15082531 15377999 15576399 15766563 15768032 15806138 16007074 16039586 16169192 16510874 16940750 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19020303 19619488 19623618 19751508 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22270359 22290435 22699938 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN TCF4 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10391247 11274345 11929833 11955436 11967263 12051714 15001769 15082531 15377999 15576399 15766563 15768032 15806138 16007074 16039586 16169192 16510874 16940750 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19020303 19619488 19623618 19751508 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22270359 22290435 22699938 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN TCF4 â—¼   DOWN_REGULATES ✅ - 49.0 1.0 ACSN 10391247 11274345 11929833 11955436 11967263 12051714 15001769 15082531 15377999 15576399 15766563 15768032 15806138 16007074 16039586 16169192 16510874 16940750 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19020303 19619488 19623618 19751508 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22270359 22290435 22699938 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18196534 9873041 9660938 14563113 9710625 11003676 19670268 10811113 9468493 15160330 15546613 12618758 11397794 10744679
JUN SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7499226 16798740 23533633 14736735 18216279
MAPK9 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 17143273 17145710 17637567 12584171 20506250 11948398 15378002 16824735 9687508 8654373 20028971 12788955 9305638 15302935 26091349 33822843 18362184 17875713 16393692 9405416 17570479 1922387 18252863 25561726 7737130 10490605 17189706 11896587 34408980 11274345 20178741 8525045 16076903 7992057 19527717 7600582 17215518 8985011 11801649 19118012 11278395 8001819 8137421 19436832 16533805 8945519 12881422 9315636 10385525 12093796 14523011 19910486 15212693 8157646 12040039 11562357
PAK2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21177766
MAPK10 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17143273 20506250 16824735 8654373 20028971 16007099 21988832 12167088 16393692 1922387 16076903 22327296 19527717 21757544 19436832 17670986 14523011 11274345 20395206 11562357
JUN TCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 16007074
SRC WASF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16317717 23354023
CHUK REL â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
SRC CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 12707358
MAP4K4 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20685151 10229185 9520446 23915189 26948423
ARHGEF7 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 24792722 16983070 18684957 16492808 9659915 10592173 14557270 11309380
CHN2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16628218 11278894 32203420
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
ARHGAP32 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23331499 12531901 12446789 12454018 12819203
PTK2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 22163037 26816343 29036929 34252134
DOCK1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 15723800 15247908 9808620 25533347 10592173 12134158
RAC1 PAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9744077 10023776 8805275 16212495 12480336 11152757 25301945 11728826 11478794 8910277
RAC1 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 8107774 10023776 8805275 9744077 23331499 8910277 22705156 20936779 9535855 19264842 19628037 11728826 20696164 16212495 12480336 11152757 9823899
WIPF3 NCK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11340081 11829459 10878810 12213210 11553796 10781580 11157975
NCK1 DOCK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
CD3E NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12110186 18955169 17617578
NCK1 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16374509 11278553 32296183 11160719
NCK1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 10026169 10206341 7862111 17474147 8810325
NCK1 WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10747096 16189514 7565724 11340081
NCK1 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11340081 26496610 17474147
SRC PTK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11476890 12531888 16919435 17496910 17517963 20027185 25572304 26552706 27216177 8892616
ARHGAP32 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12454018
PTPN12 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19595712 18482983
CDK5 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 10544291 12801906 19369195 18691976 9271228 21442427 27169346 17192257 29196663 19415658 7488156
SRC PKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11113628 11274246 12637538 21126580 10362514
SRC SPRY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18683950 15564375 12815057 15637081 16000370 15212693 12593795 18678649 16893902
SRC SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17474147 9856337
SRC TRIP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16880273 21689746 15988003 14688263 23576104 17591779 27134758 16713569 20876301
SRC DNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 7505438 12011079 9880482 11956154 15834155 19380485 9539797
SRC ABL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12748290 12522270 19534553 20841568 18083107 17474147
SRC DAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15062102 10959835 17570479 15316068 11279201
SRC PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 216.0 1.0 Omnipath 27351421 23242524 16254240 12370821 21940449 26142360 17525734 10593973 14604860 17389395 19171305 22402981 19339212 22353809 9748249 8941336 17570479 12464388 25226367 15611085 15817476 25241761 26393679 27978555 26833789 11927607 17828307 25913180 26866924 15247219 10085298 12387730 19055942 9507031 21454698 10973994 32814053 21057587 27931517 27438371 18793427 19695571 15735019 18560762 10592173 25319025 24389213 21852560 26689988 14984767 7505391 19568240 20103658 20822514 25868388 23275294 28423510 23764511 19625610 15561106 17192257 19138410 19369195 17088251 12753909 28701735 29190494 17016520 15598735 18814847 11821402 11418135 15728464 16291744 25067788 11602246 16713569 22287273 9032297 7997267 12960434 11369622 20616959 26079101 19534553 10931187 22710722 20068231 25866790 21347260 9822703 28202937 16153436 11980671 21855630 19826415 18464795 7529876 20621036 9330873 21473875 9425168 28956212 12615911 15951569 25814554 12876384 17438336 15212693 16966330 20705914 20847951 23729178 20407018 12558988 25127991 25918719 12590707 16360410 8054685 18814027 11696015 22800863 17117420 12495636 11278488 9864370 21776383 18083107 22814579 22194915 20515733 11119718 9148935 10428489 15743500 20655298 23065768 28213315 26923073 24015220 17289681 12110680 22006118 24164353 23109003 18935208 10753828 18233957 8816475 25118939 19664994 25530216 16760434 9330875 21266176 21034468
SRC GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26706435 15574420 19881549 12941962 21442024 12808090
SRC SH3PXD2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20943948
SRC SORBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19891780 20841568
SRC MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 24728074 24034250 9837958 17570479
SRC CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 27603901 22823952 7680654 9748248 28522963 19419567 19690332 16497976 15592455 19413330 25077552 17389395 19534553 20068231 28769876 17570479 20708589 19273217 18491316 18669648 16162656 25682866 12522270 18088087 22761768 26142315 17287340 27009365 10921917 9683637 24465712 27758765 24675741 12601080 18707149 16212419 15169891 7519605 17016520 11389697
SRC PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16374509 12215529
SRC ASAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9819391 16636290 24957964 17474147
SRC KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9038356 10467411 8766817 22745667 7537265 7516469 11960376 10635328 1374686 18606683 16169070 16713569 1545818 15190072
CD4 CD3E â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
ZBTB7B CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23310955 20544728 21435585 18776907 17296789 17878336 21341258
CXCR4 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11668182
FGFR1 SOS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
FGFR1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12601080 15592455 15951569
IRS1 SOS1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8316835 8810325 9832424 8621421 8530377 9852124 9003010
MAPK9 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11160134 9335553 12417588 14579029
PAK3 CTTN â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 12453877 16854367 9683637 24859002 20444238
CDK5 MAPK10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11823425
CDK5 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11160818 21825040 21378178 14712065 25525271 24091658 17096371 33999101 23294285 24121667 33981002 17185424 28361970 12941275 20519501
CDK5 DNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19651622 21765832 18088087 27725702 12855954 15302935
CDK5 DAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12077184 18076569 23506116 17629745
SOS1 PAK2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
PAK2 CTTN â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 12453877 16854367 9683637 24859002 20444238
PAK2 ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16374509 12226077 16787945 26496610
MET PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15611085 29435030 30134553 22188814 24043698 16782899 14572662 15247219 15561106 20802513 15598735
PTPN12 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19595712 10400703 9497381 21876001 11432829 11314030
DCC PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15494733 29479476 20434207 15494734
DCC DOCK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
ABL2 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20146487 16199863 20841568
WIPF1 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16582881 10087612 16055720 12372256 10878810 11331876 25416956 23414517 12437929
CTTN WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21079800 18344974 11830518
PKD1 ASAP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 23945166 9819391 19153612 18685082 22983554 16431365 16038802 16136078 23567335
FGFR4 GAB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
MET GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 10978177 17389395 19901323 10753869 15574420 15212693 10913131 10734310 11896055 20068231 10995442 9890893 16497976 14685170 17016520 18669648 11779868
GAB1 ARHGAP32 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 12819203
PTPN12 WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11711533 15588985 19167335 14707117
FGFR4 SOS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
SOS1 BLNK â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11071869 22262777 9697839 21822214
BMPR2 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 16446785 18756288 10712517 7791754
SLIT1 ROBO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21600986 10433822 16713569 14761655 1043382210433820
SLIT2 ROBO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17848514 10102268 31217826 1010226810102260
ABL2 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17306540 20841568
SLIT2 ROBO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 16226035 29317497 10102268 15130495 31217826 14761655
EFNA3 EPHA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 24003208 15114347 9576626 11114742 9330863
EFNA3 EPHA7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 24003208 15114347 9576626 11114742 10366629 9330863 933086310366629
ABL2 SORBS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 21071413 9211900 20841568