Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FGFR2 FGF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12591959 5216141
SRC SPRR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7216055 18155796
YES1 SPRR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7216055 18155796
SPRR2A CTTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7216055 18155796
SRC CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16005629 15157149
FYN CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7524477 6730342
LCK CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
SNCA GSK3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21985244 8209944
GSK3B PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673085 7514173
CSNK1A1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19293931 22083140
PAK5 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11756552 16189514
SRC PXN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574420 14665621
PXN GIT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218539 16628223
IQGAP1 PXN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15263019 22573807
FGR PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9636140 23109003
SYK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9590268
PTPRG PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25624455
GRB2 LUC7L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
PTN LUC7L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ABL1 SHANK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 SHANK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK3 ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 CTTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 ARPC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK3 UCHL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HDAC6 GRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22193721 8383707
EGFR GRK2 â—¼   COLOCALIZATION 2.0 0.8 intact 5217433 15620700
GRK2 HDAC6 â—¼   COLOCALIZATION 2.0 0.8 intact 22193721 8383707
ABL1 ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 DAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ABL1 FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CD2AP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
PTPRG ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
PAK1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11121037
PRKCA ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10713049
SRC ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 ABL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ACTA1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11018051 7680654
ACTA1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11027608
WASL ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
BCAR1 ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 6174726 18164686
PRKCA ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15590896 10592173
CTTN ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11018051 7680654
ARPC2 ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 9600938
ACTB CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11018051 7680654
ACTB ARPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 9600938
GRB2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
WASL ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10219243 11747816
GRB2 ACTR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
CDK5 ACTR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 ACTR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
CTTN ACTR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12176742
AGRN DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30478082 7531888
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPS6KB1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
PRKACA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
PRKCZ AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18650932 7232391
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
SIRT1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21775285
AKT1 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20605787
AKT1 FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15461588 17570479
ARHGEF6 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 16492808
GIT2 ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218539 16628223
ARHGEF7 PAK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PAK3 ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9726964
ARPC3 ARPC1B â—¼   PROXIMITY 2.0 0.8 intact 20404198 0911668107
GRB2 ARPC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ARPC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
WASL ARPC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32296183 25416956
GRB2 ARPC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ARPC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK1 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
SRC ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16432186 0510562103
CBL ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
ASAP1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PTK2 ASAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12058076
LRRK2 AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
SRC AXL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22327215 8381689
HSPA5 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PTK2 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221628 9285683
YES1 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 32296183 35044719
TNK2 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16247015 17038317
PIM1 BMX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217965 16186805
BMX PIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217965 16186805
BMX EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
PTPRG BMX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
GRB2 CAMK2D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
JAK2 CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
CAPN1 PTPN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 9407132 6732058
PRKACA CAPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11909964 29478550
CAPN1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8695851
CAPN2 PTPN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 9407132 6732058
CASP3 STK24 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 24556848 12107159
YES1 CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8981370 20489731
SYK CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220991 8621719
FYN CBL â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL FYN â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
CBL MET â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5215187 11894096
FGR CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12435267 7721825
CBL FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBL FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC ZAP70 â—¼   DOWN_REGULATES ✅ - 2.0 0.8 ACSN 12415267 9671496
CBLC FGFR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
SRC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
NCK2 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12810700 12215529
CDC42 RPS6KB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
CDC42 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
CDC42 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11438723
STAT3 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22218594
LRRK2 CDKL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
GRB2 CTTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
PAK1 CTTN â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6541884 18344974
CTTN PAK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6541884 18344974
WASL CTTN â—¼   COLOCALIZATION 2.0 0.8 intact 6541884 18344974
HDAC6 CTTN â—¼   COLOCALIZATION 2.0 0.8 intact 8295686 21847094
PTPRG CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
CTTNBP2 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22262902 9813110
PTK2 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17893324 22952866
PAK2 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12453877 18344974
STK24 CTTNBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 CTTNBP2NL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
LAMA5 DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16709410 10207021
DAPK1 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DAPK1 PAK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DAPK1 PIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DAPK1 PRKD1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 17703233 21172648
STAT3 DAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24217921 23438478
DAPK1 PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17703233
GRB2 DBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15834155 5217666
SH3BGRL EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
STAT3 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731598 14966128
EGFR PTPN1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 9355745 6671413
PTPRG EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
FGFR1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9480847 16713569
WAS FGR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220415 7565724
FLNA FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PAX7 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PAK2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
WASL FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11340081 16525419
WIPF1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCK2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 11557983
SNCA FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LCK FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN MAP4K5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN WAS â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216858 14707117
FYN LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 22043010
SHANK2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PAK2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
LCK GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
GRB2 SYNPO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MYLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PPP1CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IQGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
PRKCA HDAC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8307255 21952047
HSPA5 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 15146195
ITGA1 PTK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19397781 26148229
PTPRG ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
JAK2 PRKCD â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
JAK2 PRKACA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10477722 10949031
SRC JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 17158356
PTPRG JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
PTN LAMA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZAP70 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211965 10556826
WAS LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7208262 16107303
LCK SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11078745 12096713
LRRK2 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LRRK2 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
PAK1 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10385525 10791986
TGFBR2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16360132
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK3 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK3 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15310280 10402467
PTPN1 MET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18579758 6731904
MET PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521801 16782899
PTPN1 MET â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6764906 16537444
PTPRG MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
MYH9 MYLK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 3079756 3839510
MYH9 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10639334 10047984
PAK2 MYLK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10748018 10092231
PRKCA NCF1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219276 17069809
NCF1 PRKCD â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219276 17069809
RAC1 NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11893732 9255350
NCK2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 11557983
PAK3 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
PAK1 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
RAC1 PAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7215301 19264842
SH3PXD2A PAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
PAK2 YES1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
PAK2 TNK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7987728 20696164
PAK3 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
RAC1 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PAK3 RAC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PAX7 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PDPK1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
PDPK1 PRKCD â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
PDPK1 PRKCA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
PRKACA PTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA SIK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22462548 27478041
SNCA PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCA RPS6KA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
RAC1 PRKCA â—¼   COLOCALIZATION 2.0 0.8 intact 5218533 16628218
SYK PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29352133 22265677
PTPRG PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25624455
WASL PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
RAC1 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
SRC PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
PTPRG PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
PTN TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PTPN1 SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6732073 9600099
STAT3 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 15821101 6673264
PTPRG ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25624455
PTPRG SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
PTPRG STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25624455
SHANK2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
YES1 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11078745 12096713
STAT3 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132009 18447642
WASL SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
SRC YES1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SYK STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
WIPF1 WAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9405671 5221801
WIPF1 WASL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218469 16582881
ACTA1 ACTB â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
ACTR3 ARPC3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ARHGEF6 PAK1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
EGFR JAK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
GRB2 MET â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ARPC1B ARPC4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ARPC5 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 24981860
ARPC4 WAS â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
BCAR1 FYN â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
ACTR2 ACTR3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
GRB2 RET â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
EXOC8 WASHC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
GRB2 CSK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
AKT1 CSK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19262695 26344197
CSK CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23455922 31980649
PAK4 ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29100370 19778628
EGFR ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
ACTB EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 33742100
AKT1 UCHL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25640309 16027165
LRRK2 ARPC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20876399 31046837
FYN ASAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17474147 16636290
ASAP1 CD2AP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31413325 15632162
EP300 ATF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24069158 10327051
FGFR1 CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18022941 31980649
CFTR CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CDC37 PDPK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 31980649
LRRK2 CDK5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 26268594
CFTR HAX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
CFTR LAMB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CTBP1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15834423 21102443 16122695 35016035
CUL3 MCM7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26188516 21145461
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
EGFR PTPRG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25970784 31980649
EGFR EXOC8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25594178 23956138
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
FGFR2 FGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TXNIP FLNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31669268 27437069
ITGB1 FLNA â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5226870 17690686
RAC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
PTPN1 JAK2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 6732089 11970898
PTPN1 JAK2 â—¼   DEPHOSPHORYLATION ✅ 0.82 0.82 mint 6673264 15821101
JAK2 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 0.82 0.82 mint 8287447 201095 21806020
SLX4 KEAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31495888 19596235
SOX2 PAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PAK4 RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 11756552
ACTA1 WIPF1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ACTA1 FLNA â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
AKT1 GSK3B â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 15829723
AKT1 GSK3B â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 23552696
ACTR2 ARPC1B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CSK ARRB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19262695 10753943
NCK2 ABL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MYH9 ACTB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22366308 26496610 16186248
ARRB1 IGF1R â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33158816 21685939 15878855
NCK2 ASAP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NCK2 CBL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24287595
CBL FGR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 7721825 12435267
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
FER EGFR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 7623846 18271526
ESR2 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18765668 11500849
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
GRB2 ZAP70 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 7629168 23267066
HDAC6 MCM7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 23703321 26186194
SOX2 PAK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DAG1 LAMA5 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
BTRC GSK3B â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
ARHGEF6 GIT2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
MAPK3 RPS6KA2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
PTK2 YES1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ACTR2 WASL â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ACTR2 WAS â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ARPC2 WAS â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SRC TNK2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CSK LCK â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15144186 12485116 31980649
CDC37 ABL2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25036637 32707033
ACTA1 ARPC2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
ESR2 ACTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21182203 21951318
ARPC4 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
FLNA ARRB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17620599 16611986
ARRB2 SRC â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
SRC BMX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 10688651
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
FGR CDC37 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
CDC37 CDK5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9150368 23455922 33961781 21163940
ZAP70 FYN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 7760813 16189514 16713569
KCNA3 KCNA2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10428084 33961781 12944270
ACTR2 CTTN â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
FYN PRKCD â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ACTR3 ARPC2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTA1 ARPC5 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ACTA1 ARPC4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ACTA1 ARPC3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ACTR2 ARPC3 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ARPC1B ARPC2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
GSK3B CDC37 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29568061 23455922 33961781
BCAR1 LCK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9020138
CD2AP FYN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17474147 31413325 10339567 16713569
CDC37 FER â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25036637 32707033
LRRK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
CFTR MYH9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 22038833
GRB2 FLNA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21706016 17474147 12577067
SRC GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12624098 9016807 16713569 16189514 11964172
LRRK2 PAK6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24510904 26375402 24947832
PAK3 RAC1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
ARPC2 ARPC3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
ARPC3 ARPC4 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
JAK2 PTPN1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CBL CSK â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19380743 11149930
NCF1 ACTB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16375898 11027608
MET CBL â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 6538879 18273061
MET CBL â—¼   UBIQUITINATION ✅ 0.86 0.86 mint 11894096 5215187
LCK CDC37 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 34079125
ESR2 MYH9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21951318 25604459
FLNA MYH9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
FYN SDC3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9553134 16189514 16713569
RAC1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21454543 31046837
SRC PAK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12215529 16374509
RAC1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11021801 16189514
CBLC YES1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CBLC FYN â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
AKT1 PRKCZ â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
BCAR1 GRB2 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
ACTA1 ACTR3 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ARHGEF7 CDC42 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ACTA1 WAS â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
ACTA1 WASL â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
NCF1 PRKCZ â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
AKT1 CDC37 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
ITGB1 PXN â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BCAR1 ABL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 7780740 8810278
ACTR3 WASL â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR ARRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
LRRK2 CDC37 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16321986 20642453 22612223 23075850 26355680 18367605
CDK5 CDK3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 23455922 33961781 28514442
DDR2 SRC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11884411 16186108
EGFR WASL â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
EGFR PIM1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
EGFR STAT3 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 22693070
SRC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
LAMC1 LAMB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17517882
ARPC4 WASL â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CTNND1 EGFR â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PARK2 SNCA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
FGR WAS â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ARHGEF7 PAK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CDC37 LRRK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PTPN1 SRC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ACTA1 ACTR2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ARHGEF7 RAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
BCAR1 PTPN1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
EGFR TNK2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
FLNA ITGB1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PTPN1 IGF1R â—¼   DEPHOSPHORYLATION ✅ - 0.87 0.87 Signor 11884589
PAK2 PAK3 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CDC37 AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31980649 24869908 22504172 12176997
FLNA ARRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17984062 17620599 16611986
CDC37 AURKB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25036637 31586073 26186194 29568061 32707033
CD2AP BCAR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12618476 10339567
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
JAK2 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24240702 23838182 9363897 10358079 10635327 16273093
SRC ESR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11032808 12630920 15604093 11013076 12095943
JAK2 FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10551884 16713569
PAK2 GIT2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26496610 17353931
GRB2 MYH9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20936779 24189400 12577067
SRC RET â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 32062451 10070972 16189514
ASAP1 CTTN â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
GRB2 PTK2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
LCK ZAP70 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EGFR NCK2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
FYN WAS â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CBL CD2AP â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
JAK2 STAT3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
STAT3 SYK â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CBL LCK â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
EGFR MET â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
ITGA1 ITGB1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
BMX STAT3 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MAPK1 STAT3 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
ABL1 ABL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27229929 12569093 15735735
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR ARRB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR CDC37 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25036637 31980649 23956138 24189400 12471035
CDC37 CDK7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29568061 8666233 26186194 33961781
DAG1 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11724572 17474147
UCHL1 EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32494592 32042339 31980649 20029029
EGFR FGR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
SRC FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16966330 31980649 28514442 19711372 9169421
NCK2 GIT2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
RET GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7665556 10995764 15677445 9393871 8183561 32062451 16189514
RAC1 IQGAP1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 18809683
ARPC3 WASL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
LAMB3 LAMC2 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
FGF7 FGFR2 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
EGFR PTPN1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
FGFR2 GRB2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
GRB2 WAS â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ARPC3 WAS â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
EIF3H NCK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BCAR1 PTK2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
GRB2 TNK2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
EGFR CSK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24797263 24658140 31980649 16729043 25402006
CSK ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 9819392 18829532
PTN GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LUC7L2 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FYN GSK3B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
GSK3B CDK5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
MAP4K5 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16914735
PRKCH GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19836308
PRKCA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19836308
PXN CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15719014 25241761
CDK4 LUC7L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDC37 LUC7L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PDPK1 LUC7L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SRC ABL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11494128 12522270 11781820 17318191 17474147
FGR ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16787943 11847100 16076903
YES1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16787943 11847100 16076903
PTPN1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9566916 16537444
TINF2 ACD â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383534 28514442 33961781 21044950 32296183 25910212 15231715 26496610 16880378 16713569 25416956 15181449 16189514
PDPK1 AKT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11438723 11313365 23397142 11278835 14500673 26264872 32876514 27563096 26256536 9368760 12149249 11445557 31467278 11825911 10226025 21775285 10698680 22569334 16189514
TNK2 AKT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10652228 11394904 18470881
AKT1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16256741 10896934
FYN ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18541700 23144976 11536198
ARHGAP35 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 1894621 10873807 32203420
PAK1 ARHGEF6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ARHGEF6 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15649357 15306850 25241761
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
GRB2 ASAP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21706016 31980649 20936779 21988832 28514442 19380743 17474147
ASAP1 SRC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17474147 9819391 16636290
EGFR BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17145710 17570479 15951569
DBN1 BTRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCA CAPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11950589 8070569 17570479
ESR2 CAPN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
SRC CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22203672 29899407 17141222 18996392 12941616 15135048 18273061 10829062 31120930 19861161 7782294 16713569 8635998 11994282 17094785 16636290
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
ZAP70 CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10074432 29053960 10078535 11353765 11133830 9407100 8798643 10779765 9988730 22266821 16503409
CBL IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18632619 17635922 10514377
CDC37 SRC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 32707033 31980649 11085988
PAK4 CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31871319 26344197 17353931 31478661 11756552 20936779 9822598 29734338 32707033 16189514 26598620
PAK6 CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31980649 20936779 11773441 32707033 16189514
PAK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31871319 32296183 17353931 25416956 20696164 20936779 9822598 10320322 9535855 21311754 16204230 32707033
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SNCA CDK4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKACA CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22798526
MET CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11439336
PAK3 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26490115 29152154 16854367
KEAP1 CUL3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15367669 28186440 15572695 20864537 25742418 33130828 20534351 20027226 30765703 32854194 23727018 25628777 26757824 17439941 16449638 16790436 21357422 19818716 32341456 20421418 22245129 26219975 22558124 32296183 24896564 15983046 30383469 18251510 24127568 22911784 33391509 15282312 20865015 24322982 21145461 20599909 17822677 22448038 18417180 30273379 15601839
SRC DAG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11724572 12795607 17474147
DMD DAG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10932245 7592992 19109891 10355629
LAMA1 DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11798066 16709410 7925941
DNM2 HMGB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ZAP70 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 22973453 25402006 16273093
PTPN1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 6671413 9355745
NCK2 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 22973453 9843575 16713569 25402006 1333047 10026169 9737977
STAT3 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18367518 21590492 23504318
PTPN1 EGFR â—¼   PHOSPHORYLATION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 6732094 9050838
EGFR PTPN1 â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 25796184
YES1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 22430206 11160627
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
STAT3 ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23295773 21546410
FGFR2 FGF7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7687739 9582367 11121055 10950949 11714710 10339576 1309608 7499435 8663044
PRKACA FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20658524
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
JAK2 GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8536716 17474147 8950973 7500025
MET GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9660480 11439336 8662889 19433454 15546961 11063574 7511210 21222362
HIP1R HIP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11063258 11889126 33961781 28514442
LAMA5 ITGB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 LAMB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 LAMB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
ITGB1 LAMC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11964076 16413178 16581764
PTPN1 ITGB1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 201095 21806020 8287447
LAMA2 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278916
LAMC2 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10842354
LAMB1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10842354
SRC ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11723131 11259684
JAK2 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10925297 9553131
PRKACA LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21390248 24351927
PDPK1 MAP3K7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17496917 15125833 16056267
NCF1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16778989 10400704 27558335
MAPK1 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
NCF1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16778989 10400704 27558335
MAPK3 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
MAPK3 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14993270
SRC MET â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24728074 9837958 20624308 24034250
MYLK MYO18A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 6934518 6893940 4522294
NCF1 PRKCD â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
NCF1 PRKCA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
NCF1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
YES1 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16374509
STAT3 PIM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 11533249
PTPN1 PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17570831 15133032 11350745
SRC PTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14563642 19459784 18097461
PTN SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16908672 8175719 9553134
CDC42 PAK3 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
GRB2 WASL â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ARPC2 ARPC4 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
DNM2 GRB2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
ACTB CDC37 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NCK2 PAK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PTK2 PXN â—¼   PHOSPHORYLATION ✅ + 0.9 0.9 Signor 15688067
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
MAPK1 RPS6KA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CSK SRC â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
LAMA5 LAMB1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
BCAR1 SRC â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
ABL1 CBL â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CBL MET â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CDC42 PAK4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PAK2 RAC1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ACD TINF2 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
ACTR2 ARPC2 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
ACTR2 ARPC4 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
PXN BCAR1 â—¼   UP_REGULATES ✅ + 0.91 0.91 Signor 27447856
ACTG1 CDC37 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
ARHGEF7 GIT2 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
FYN CDC37 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 25036637 31980649 28514442 32707033
LAMA2 DAG1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 16709410 7925941
DAG1 DMD â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
CBL FYN â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CDC42 PAK6 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
IQGAP1 RAC1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CDC42 IQGAP1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CDK4 CDC37 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 24981860
PTK2 SRC â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
SRC CTNND1 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 11382764
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EGFR STAT3 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
AKT1 GSK3B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
AKT1 PDPK1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
NCK2 PAK1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PXN PTK2 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 25795725
LAMA5 DAG1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 30914516 10207021
GRB2 WIPF1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 21706016 20936779 21988832 28514442
SRC PTPN1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6672195 16115959
SRC PTPN1 â—¼   PHOSPHORYLATION ✅ 0.94 0.94 mint 6732073 9600099
SRC PTPN1 â—¼   DEPHOSPHORYLATION ✅ 0.94 0.94 mint 11007774 6671922
PTPN1 SRC â—¼   DEPHOSPHORYLATION ✅ 0.94 0.94 mint 6764906 16537444
DAG1 LAMA1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
FYN YES1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ARHGEF7 PAK3 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
PTK2 PXN â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
CBL SYK â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
WAS WIPF1 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
PAK1 ARHGEF7 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218539 16628223
WAS CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8625410 5221000
IQGAP1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5221163 8798539
CDC42 IQGAP1 â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 18809683
PAK1 GIT2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 25852190 16628223 11157752 31980649
PAK1 PAK2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 23455922 32707033 31980649
WASL WIPF1 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
CTTN HIP1R â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ARPC2 WASL â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CBLC SRC â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
IGF1R PTPN1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
CD2AP GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19380743 10339567 21988832 21706016
DAG1 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10903901 17474147 7744812
NCK2 WIPF1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 28514442 26186194 32296183
RAC1 PAK3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11478794 11862216 25301945
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
LAMA5 LAMC1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
DAG1 LAMA2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CDC42 PAK2 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
ARPC4 ARPC3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 11162547 32296183 24981860 26344197 22939629 23148219 22863883
SRC BCAR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10085298 21034468 10487518 11514617 10542110 15020686 16849545 12397603 12615911 17038317 10739664 12972425 17129785
CD2AP CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22706086 15128873 25036637 17072306 25872741 12559036 11067845 33627783 12618476 12672817 17188587 17020880
FYN CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9677430 8621719 12244174 7782294 10629042 119942 7642581 15556646 12231245 9311917 9535867 8626543 10799548 16713569 16503409 10092522 8900205 8995358 25814554 9890970 15190072 15208330 12941616 10829062 11239464 8662998 17094785
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7744004 12879077 23455922 15548653 10802735 24276241 31871319 10684602 21167153 19596003 12606577 10360579 18057010 20936779 11157984 25150978 18426980 21029865 12650940 9705280 8107774 23175184 21048135 31478661 9535855 16678097
WASL CDC42 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 31871319 16293614 9422512 10781580 20936779 21311754 10724160 11943145 11331876 15834156
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
WASL GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28514442 27107012 33961781 21706016 31980649 10781580 20936779 16713569 10087612 25416956 17474147
LAMB1 LAMC1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CDC42 WASL â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
FGF10 FGFR2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
AGRN DAG1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CDC42 TNK2 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
CBL ZAP70 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CBLC EGFR â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CDC37 CDK4 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ARHGEF7 PAK1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CTTNBP2 CTTNBP2NL â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTTNBP2NL STK24 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTTNBP2 STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ACTR3 ARPC1B â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CDC42 WAS â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACTR2 ARPC1B â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ARPC1B ARPC5 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ARPC1B ARPC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ARPC1B ARPC2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ARPC1B ARPC4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
FGF10 FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 23331499 25241761 21071413 16597617 9582367 10339576 12591959 8663044 25772309
CSK SRC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 17192274 18268019 22677902 23691193 24030100 27452906
CSK FYN â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10790433 11181701 12485116 15713798 19290918 8011291 8986721
CSK LCK â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 10790433 11181701 12485116 15713798 19290918 8011291 8986721
IGF1R CSK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 10026153
PRKACA CSK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9224730 11181701 20826718 31125786 12600271
CSK FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1985196 8262983 11489946 16537894 9647655 25720756 18691976 10366594 19369195 1533589 1699196 7524477 16713569 15713745 14967142
CSK FGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 11489946 7515063 16537894 8612628 14967142
CSK YES1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11489946 16537894 19369195 18691976 7690925 12640114 15592455 18083107 14967142 16439366
CSK SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 55.0 1.0 Omnipath 11489946 23051580 20657842 20337577 7592628 23824743 21940449 26453921 22323292 14665621 17525734 14967142 3103926 23159740 16227616 1383688 12387813 20525307 10698938 7525268 19534553 16537894 26234813 10592173 12468645 7513429 24632723 7687537 21442427 22689825 25372749 11007774 9208935 18614016 28974561 21632985 19369195 17855352 7678701 23378895 9523754
CSK LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 56.0 1.0 Omnipath 20346773 19901323 10692391 11489946 22566970 24463463 2141684 16497976 15592455 20813252 10799545 14967142 27547268 24764511 28522807 16537894 12485116 8193535 24227778 17897955 8183556 22426112 89123626 15489916 14610046 23109003 18691976 28448599 17947241 1639064 12414720 15144186 27460989 24816556 22507872 8631775 15743820 25979654 8945479 11181701 27045023 25595912 15259016
CSK PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18823558 21829547 9890993 27803182 21062671 7529872 21709741
CSK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17389395 18707149 27447856 11695992 7529872 9890993 14665621
RPS6KB1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17053147 21233202 8250835 15905173 19339977 19720745 16286006 12713446 20647036 20832730 18423201 11108711 17052453
PRKCZ GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18353303 14657655 11481324
AKT1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 99.0 1.0 Omnipath 17428466 15207235 17145710 12052830 10729337 8250835 11756412 11923280 16914735 17623045 16697215 8524413 12054501 20398329 18372248 21506126 20028971 12040186 15808505 16543730 20138985 23331499 21303971 16009706 10385618 20214616 23180781 9373175 16039586 15829723 18988627 16282323 11577096 11035810 18669648 18216173 15169778 12851486 16123141 11882383 23109003 9065430 18691976 22094462 10949026 22710759 11715018 12459251 18636226 17192257 11254732 11278246 20858269 9812896 9582355 15023346 17680028 19369195 7945242 12900420 23552696 18387957 10722653 20832730 18570873 12147701 18505846 17052453 17693255 18218901
MAPK3 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16039586 28646232
PRKACA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16543730 15845746 18691976 19836308 8524413 12054501 16039586 12147701 16522636 11035810 18669648
MAPK1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16039586 28646232 18451303
GSK3B CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 11152665 20537194 10385618 11124803 12969793 19757160 16732330 10486203 16039586 14536078 18167338 12459251 12615961
PAK5 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 11756552 12032833 16189514 32296183
PXN BCAR1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 ACSN 12473693 14749719 15094799 15308668 15688067 16000375 18287025 18829532 18835194 22043013 29021139 9819392
PXN BCAR1 â—¼   SHARES_COMPLEX 12.0 1.0 ACSN 12473693 14749719 15094799 15308668 15688067 16000375 18287025 18829532 18835194 22043013 29021139 9819392
ZAP70 PXN â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
CDC42 PXN â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10934474 11248548 11340065 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18719708 19741094 21178402 22126964 22821962 27248291 7761442 9831565
FYN PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7617039 10804218 16713569 23128389
CASP3 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11511102 11825902 11447317
ABL1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7615549 15817476 11774284 16254239 15107421 12408869 15572663 11695992 15592455 16094384 10823820 20841568 16713569 9603926 7537852
MAPK1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10753946 15494312 11784715 14636584
PAK1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 26598620 10330411 11096073 16717130 14580336 18986306 27542844 28214467 25472536 17440071 23317503
PTK2 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 16298995 26053221 15688067 15572663 15592455 7963537 17389395 25405379 26546726 9658172 15107421 22581436 10823820 16254239 25226367 15817476 10330411 9756887 19543320 9054445 10545505 18707149 29127427 15494312 10764815 7537852 9442086 33823745 12408869 20419088 20655620 22270917 18669648 28373581 10455189 16094384 23936270 19138410 22638989 11337490 11514617 27402964 16713569 7615549 10931187 11774284 26700725 27708220 20068231 20473365 28928239 7561682 34475475 28427224 28068967 8922390 24885567 23209645 27669437 15212693 26711338 9422762 11304546 28214467 26697169 12065577 28415719 10753828 11919182 24364863 9230116 11113628 21741599 10417825 15252114 24642576 22044652 21034468
SRC PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 9636140 28214467 15572663 15592455 16713569 14665621 25795725 7537852 7615549 25405379 11774284 26700725 25182764 15107421 7534286 2472406 12408869 11695992 17570479 10823820 7525621 20103658 16254239 15817476 23109003 27447856 28626446 16094384 18363833 19543320 24364863 28376152 19138410 25323586 27941878 23457577 10085298 22638989 27669437 15212693
PXN BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11313252 9418872 11577104 9759889 8810278
GRK2 CSNK1A1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 14636583 16908539 16630821 15691767 20844016 24925320 18815277 24845016 21695114 17960137 23719536 14614827
MAPK3 GRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 19651622 18767875 23772028 18088087 10574913 10727525
PRKACA GRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11278469
PRKCA GRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11042191 9013639
SRC GRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12624098 16725308 11278940 11566877 16189514
PRKCD GRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11042191
GRK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 10852916 11813001 10617630
ABL1 BCAR1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 CBL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
PAK2 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 18161990 20841568 11121037
LCK ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16076903 16787943 17570479 11847100
FYN ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12522270 16787943 17570479 16912036 16076903 17474147 11847100
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
ABL1 PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18923184 17126298 9109492 16631755 19737086 28637715 20841568 10713049
ABL1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9525940 11494134 16713569 20841568 10829062 17389395 16955467 12604776 9890970 10391678 9195915 14725908 7925293 11997497 12522270 15556646 9102067 11239464 11994282 9174058 12475393 20675402 19380743 14604282 8626543 15212693 19823681
ABL1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8940193 16846476 20841568
ABL1 DNM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17474147 20841568 19833721
ABL1 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 18083107 17129785 19534553 16212419 8810278 15951569 20841568 7780740
ABL1 CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 19901323 26944284 15689152 19690332 16497976 24975575 19413330 20841568 18083107 19534553 20068231 19700222 9038181 14757045 23348931 11113134 10896159 18691976 28646794 29063113 24600352 12372285 19369195 18794154 15212693
ABL1 ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15084284 20841568
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23329794 12637538 16891660 28174535 20841568 12505989 15212693 15024053
ABL1 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9826708 12766170 9391119 9242692 10506185 8547236 10069803 7687741 10490849 11741535 21777671 8906793 12475979 9444958 7513258 7961992 15475459 9252406 7838524 7731718 8662889 7708691
ABL1 ABL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12569093 15735735 20841568
ABL1 NEDD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 8668148 8879209 20841568
ABL1 CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11891774 20841568
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20861316 11113114 12408982
ABL1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16705159 15923602 15793561 25821558 9111318 15143187 16705160 11593427 20841568
ABL1 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17389395 19901323 16199863 19664994 20068231 18707149 18452278 20146487 20841568 19415658
ABL1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20861316 17306540 20841568
SRC ABL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12748290 12522270 19534553 20841568 18083107 17474147
ABL2 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17306540 20841568
ABL2 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20146487 16199863 20841568
ACD TINF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 16880378 15181449 25416956 21044950 15383534 31515488 26496610 16713569 15231715
ACTB CDC42 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
CDC42 ACTG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
RAC1 ACTG1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 18391171 16262445 11231582 9600938 15040784 12743368
ACTR2 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ACTR2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
WAS ACTR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16293614 17145710 10467124 14749719 9843499 16702231 24872192 10511705 12054568 8625410 19643989
PAK1 ACTR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16293614 10467124 14749719 9843499 16702231 10511705 12054568 8625410
WASL ACTR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16293614 10467124 14749719 9843499 16702231 10511705 12054568 8625410 15834156
ACTR3 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ACTR3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
PAK1 ACTR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16293614 10467124 14749719 9843499 16702231 10511705 12054568 8625410
WASL ACTR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16293614 10467124 14749719 9843499 16702231 10511705 12054568 8625410
PDPK1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11687500 11747822 12670391 15802604 17680028 18802401 19109239 19122654
RAC1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
PRKCZ AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11585925 15884057 14560023 16189514 11748077 18353613 11723139 10085094
PDPK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 156.0 1.0 Omnipath 15505410 12538620 12176337 19951971 24352480 11752451 19401591 11369519 10698680 10601311 15718470 24950409 20481595 24169049 10570282 16798838 14993273 11500365 9368760 19844585 17680028 7637810 9169478 26256536 7722458 9094314 12750173 11438723 18802401 9252186 23331499 18456494 9104825 10592173 16189514 20361045 18988627 11278835 20163786 20333297 20041157 12808134 19602588 8630736 10207050 11241670 10438924 9868760 25912234 20153221 25582703 11445557 21775285 12149249 14666721 18596232 9512493 23397142 11809791 12167717 21798082 16033886 10679787 16787925 29562639 15550174 21071413 8978681 10833263 19203586 10226025 26937223 14500673 20161206 11136732 11825911 11042193 9642236 22569334 18662999 9736715 12242303 11313365 11598012 11134526
TNK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22322295 11394904 25678401 20333297 10652228
PDK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19951971 24931005 16341064 10438924 21998731 29562639 11369519 23006971
PPP1CB AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
CASP3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17544405 12124386 10579725
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
RAC1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 20338997 15808505 20138985 20214616 21474067 19568798 15169778 19720745 18925875 10949026 11715018 19143635 12393431 18636226 10617634 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
RET AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12600984 15994200
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
AKT1 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 15911620 15998799 17570479 30680530 11707464
AKT1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 23331499 17680028 20214616 17688959 20398329 16537363 17052453 19575820
AKT1 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17081983 18691976 11579209 16189514 10480872
AKT1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11435472 14749719 24886428 14585966 23397142 9032240 12138087
AKT1 NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12734380 34264265 25761062 33139577 20920494 10559253 26774451
AKT1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11943559 23331499 25241761 21071413 12183455 15149849 11438723
SRC ARHGAP35 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
SRC ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 19901323 21937717 18541700 20068231 9819392 10592173 11309200 16497976 15592455 17570479 16513268 7542246 30664792 17016520 32540970
PAK2 ARHGEF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16374509 17392278 32296183
ARHGEF6 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23455922 11157752 9659915 10592173 15688026 21900206
PAK1 ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 20936779 16101281 11096073 10330411 11157752 16628223 9726964 16492808 9659915 10592173 16407834 17392278 29997244 32814053 25472536 23455922
CBL ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23175185 12935897 16407834 22588125 14505571
PAK2 ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16374509 12226077 16787945 26496610
LRRK2 ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21048939
ARHGEF7 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 23175185 12935897 16407834 22588125 14505571
ARHGEF7 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 24792722 16983070 18684957 16492808 9659915 10592173 14557270 11309380
ARHGEF7 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15649357 16983070 9659915 25150978
PAK1 ARPC1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 28007610 20603326 14749719 25472536
WAS ARPC1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11943145 10861055
WASL ARPC1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15894313 10781580 11943145
ARPC2 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ARPC2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
ARPC3 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ARPC3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
WAS ARPC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 23148219 12769847 9889097
ARPC4 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC4 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ARPC4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
MYH9 ARPC5 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
SRC ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17456469 17456551 16432186
MAPK3 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
MAPK1 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
CSNK2A2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877451
SRC ASAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9819391 16636290 24957964 17474147
ATF2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
MAPK1 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10777545 17081983 21098032 9430721 12110590 20068231 19690332 15304344 19413330 10878576 15192015 7737129 18669648 19647037
MAPK3 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10777545 12110590 20068231 15304344 15192015 19647037
PRKCA ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1661585 9436983 19176525 92095966
PRKACA ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1661585 15105425 92095966
BCAR1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
BCAR1 CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
FGFR1 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11019781 12601080
FYN BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17129785 9188452 9020138 10739664 31413325 16713569 11181827 9360983 17474147
PTK2 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 8649427 7479864 12135674 15673687 8810278 9038154 8670206 9285683 11604500 11119718 12480533 24939893 8621540 11577104 9360968 9148935 10592173 12119061 12972425 9360983 10092764 21855630 10753828 11839772 18233957 10545505 12615911 8662921 11514617
CASP3 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11511102 11447317 10712510
SRC BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 19901323 24962474 11514617 8670206 15316024 20927395 8070403 17389395 12480533 22710723 30422386 25976166 17570479 21963850 12972425 20103658 17129785 10487518 15817476 21301050 10739664 17038317 21765460 17016520 12397603 15212693 15020686 10542110 23457577 10085298 12615911 15272013 21034468 11604500
PTPN1 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 9418872 15588985 9407132 8615784 8940134 15866871 12023880 16644720 10889023
SRC BMX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 27601470 17570479 16189514 10688651
BMX PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 27994061 18437915 21454698 21289086 16291744 22940691 12639965 17117420 23716717 28053086 16920701 16415178 20473329 20658524 21918175 15735019 23466867 17692050 16189514 15707572 20501847 12482769 11909938 16153436 20802517 14656986 15371459 11331870 14645233 16782899 15026417 15561106 14761895 17215324 19815712 25617365 11839772 27226554 29311227 17449913 12871985 17088251 17317726 22490227 12876384 18250445 18664639 32839549 21059620
BTRC WEE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 17145710 15070733 19847258 16085715 15340381 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
PTPN1 CAPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9407132 12857726 19712109 8223493
CAPN1 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9407132 12857726 19712109 8223493
PRKACA CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11909964
MAPK1 CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11319218 14993287 10644690
MAPK3 CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11319218 26248159 14993287 10644690
CAPN2 PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9470132 8223493 9407132
CASP3 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10224094 9463408
CASP3 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9712143 9171063 11070003 9786869 16204230
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
CBL CDC37 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
CBL ZAP70 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11353765 15169881 18835194 20189481
SYK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 72.0 1.0 Omnipath 16289966 15922744 9525940 19419964 11133830 33512474 18273061 10829062 10799548 10540342 10934191 7721825 12435267 11331248 12604776 9890970 11042121 10092522 11997497 12522270 9857068 9988765 15556646 11742985 15536084 8621719 9102067 22880054 10551821 11239464 10617633 11994282 10570266 12881521 9535867 15577829
FYN CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 97.0 1.0 Omnipath 9525940 7642581 8626543 7782294 15208330 16503409 16713569 10829062 10799548 10934191 8900205 8551236 8662998 8995358 19734451 12604776 9890970 10592173 17570479 10629042 17094785 10092522 11997497 12522270 15556646 12244174 8621719 9102067 22880054 9311917 11239464 19904769 11994282 12941616 9535867 25814554 12231245 15190072
PRKCA CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10358153 17570479 25814554 11024037
YES1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10092522 11994282 11997497 12522270 9525940 12604776 9890970 9102067 10829062 10799548 11239464 10934191
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
LCK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 9525940 10829062 10799548 10934191 7721825 16107303 12604776 9890970 17570479 11904433 9178909 10092522 11997497 12522270 8621719 9102067 11239464 11994282 11741956
CBL ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 11133830 10779765 10358158 16503409 8798643 20189481 22266821 23109003 18835194 10074432 10078535 15268851 15169881 26192618 9407100 9988730 11353765
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16397241 15123609 23331499 25241761 21222362 11894096 18672314 21163258 19450681 18273061 35309168 17533376 19433454 17635922 10514377
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12727845 15677445
SRC CBLC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9988270 20525694 24425877 14661060 22888118
CBLC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10362357 22888118 17635922 10514377
CSNK2A2 CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20068231 15082798 19413330 12930845
WIPF1 CDC42 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11340081 11829459 10878810 12213210 11553796 10781580 11157975
SRC CDC42 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
PAK6 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20936779 11773441 16189514
SRC CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14506284 26816343 9626657
IQGAP1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 17145710 9182573 8798539 12377780 9199170 8670801 17563371 8702968 12745076 15695813 21876773 8756646 12900413 18809683
CDC42 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8107774 10559936 25416956 10320322 23331499 15020669 11340065 15003621 20936779 10934474 11413130 17353931 9535855 11950587 19628037 32296183 16204230 20696164 11248548 9822598 18719708 10613909 9823899 10461188
CDC42 WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 10360579 10559936 10940259 8643625 9422512 9742969 25502805 10684602 15075243 10511705 15020669 12235133 12769846 8625410 11340065 15361624 16189514 15003621 16293614 20936779 22252508 10934474 11413130 15713627 10747096 11950587 27871158 10724160 10360578 10713100 10467124 10068673 9660763 25758716 11248548 10802735 31515488 18719708 10613909 10461188
CDC42 PAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11157984 20936779 10934474 10559936 11413130 11950587 11248548 15824104 15020669 18719708 10613909 10866202 11340065 15003621 10461188
CDC42 PAK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 10559936 11756552 29734338 15020669 16189514 11340065 15003621 20936779 10934474 11413130 17353931 22653441 11950587 26598620 11248548 9822598 18719708 10613909 10461188
CDC42 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17145710 10559936 11331876 10940259 9422512 11943145 10511705 15020669 8625410 11340065 10219243 15003621 15834156 16293614 20936779 10934474 11413130 15713627 11950587 10724160 10467124 10781580 11248548 18719708 10613909 10461188
CDC42 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 17353362 10733591 10873802
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
CDC42 TNK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15123659 10360579 20936779 24413169 11394904 10684602 10802735 16189514 16052498 20086093 11157984 21637378
CDK4 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK7 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 7533895 14597415 19847258 8139570 12814430 17386261 16327805 16782892 28368408 17884153 19667075 15703371 14754892 12648680 11900249 12459251 16697054 19809470
YES1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18479465
STAT3 CDK5 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
STAT3 CDK5 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
FYN CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 24872417 19901323 9038181 10896159 18691976 20506281 29063113 20068231 16497976 19413330 14757045 12372285
CDK5 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11160818 21825040 21378178 14712065 25525271 24091658 17096371 33999101 23294285 24121667 33981002 17185424 28361970 12941275 20519501
CDK5 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25038288 16651438 19156541 12763138 28114390 16879821 23941877 15096606 26198700
CDK5 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 10544291 12801906 19369195 18691976 9271228 21442427 27169346 17192257 29196663 19415658 7488156
CDK5 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20058876 17114649 12176333 12950086 19298660 19664994 12176334 15542607 19413330 23537649 19036346 19664995 21825040 11604394
PRKACA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 28003367 23060444 25867080 21455600 30600261 1716180 28242698 19328185 32102849 92316961 19095655 14602047 7530719 10581361 11053017 9385646 25330774 15657296 1377674
PRKCA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 92316961 15212693 26888287 1377674
CSNK1A1 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20203178 10852916 10617630 11813001 25009465 24798925
CSNK2A2 WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18088087 12769847
PAK1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 12872159 16999872 18354494 20361981 23291169
SRC CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17389395 11382764 19138410 20068231 18707149 17194753 23457577 26477567 14996911 17016520 18669648
MET CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17496910 22558232 12040186 19568798 14585353
FYN CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 26477567 11777936 17194753
EGFR CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 17145710 22558232 18950621 23481205 25402006 12040186 24797263 9535896 17389395 20068231 19568798 27316454 14585353 17496910 24189400 15657067 24658140 31980649 26067913 15951569 14996911 17016520
PAK2 CTTN â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 12453877 16854367 9683637 24859002 20444238
PAK1 CTTN â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 12453877 16854367 9683637 24859002 20444238
PAK3 CTTN â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 12453877 16854367 9683637 24859002 20444238
PRKD1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26490115 29152154 19038333 20363754
PAK1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 30562756 24859002 12453877 18344974 29152154 21079800 26490115 27135389 16854367 20444238
SYK CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 27758765 8636079 25241761 10438543 16189514 28306714 11389697
MAPK3 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10537323 17081983 18088087 15144186 21079800 16964243 20444238
FGFR1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12601080 15592455 15951569
PTPN1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 27824079 18515860 18387954
MAPK1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10537323 21079800 17570479 22514278 20444238
FER CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 27758765 17389395 12522270 9748248 18088087 16176974 20068231 18707149 9722593 15169891 16497976 17287340 19413330 15592455 10921917 18491316 18669648 17016520
HDAC6 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21220424 21847094 17643370
SRC CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 27603901 22823952 7680654 9748248 28522963 19419567 19690332 16497976 15592455 19413330 25077552 17389395 19534553 20068231 28769876 17570479 20708589 19273217 18491316 18669648 16162656 25682866 12522270 18088087 22761768 26142315 17287340 27009365 10921917 9683637 24465712 27758765 24675741 12601080 18707149 16212419 15169891 7519605 17016520 11389697
CTTN WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21079800 18344974 11830518
CUL3 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
CUL3 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
KEAP1 CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20534351 30273379 15983046 24896564 15282312 17439941 32341456 26219975 32296183 26757824
LAMA2 DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 30530204 16709410 7925941
SRC DAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12795607 18982058 17474147 11724572
SRC DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 28976934 21785723 17803936
MAPK1 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15616583
MAPK3 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 25241761 15616583 26769850
SRC DDR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 28270508 11884411 16186108 18083107
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
PRKCA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 11447289 8321321 11313945 25402006 12040186 20888375 15302935 6321473 1860884 12878187 6090944 19568798 14585353 17496910 21386996 24658140 2984676 11940581 31980649 15212693 85012702 19615955 2987962 12845332 3379075 7805884 10816576 15567848 16488589
FGR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 31980649 24658140 11160627 25402006
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
JAK2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17389395 10635327 17081983 10358079 16273093 16799092 18691976 10459005 9363897 15284024 23838182 17016520 18669648 15302935
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
PRKCD EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 11447289 8321321 11313945 12040186 15302935 6321473 1860884 6090944 19568798 14585353 17496910 21386996 2984676 11940581 85012702 19615955 2987962 12845332 3379075 15567848 16488589 17956904
PRKD1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17081983 3138233 18220336 19369195 18691976 2987962 10523301 2984676 19413330 16083266 17192257 26465157 18669648 15302935
MAPK3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 1651322 17081983 3138233 15901825 16785992 1939237 91332050 27531070 17570479 2543683 2115882 34086370 17192257 1651323 15302935
EGFR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23956138 12070153 20145033 14967450 20032199 21573184 25402006 10358079 23894143 14966128 24135280 25241761 14963038 24189400 15657067 24658140 15485908 15950906 18258752 31980649 9756944 22693070 12873986 15951569 15284024
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16713569 16919435 25402006 10806474 29435030 20473329 7657702 19339212 17496910 15657067 24658140 19625610 7529872 20802513 31980649 10545505 24043698 15951569
EGFR NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 1333047 23331499 10026169 9737977 24658140 16713569 25402006 9843575 1333046
EGFR PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 25796184 31980649 8621392 12573287 18253097 11106648 11506178 24658140 7540771 9050838 9355745 15982634 25402006 10889023 7693694 8999839
EGFR TNK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 20359967 8647288 20432460 17182860 15951569 8497321
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
PRKCD EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11020388 17434128 12379484 15006641 18053091 15212693 12590608
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
ESR2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11013076 12095943 12630920 11032808
FER STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18083107 17389395 19534553 7701321 16568091 19147545 10878010 19159681 15592455 15951569 12763138 12738762 18234692
FER PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9786960 15226396 11106648 12377785
FGF7 FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 16597617 11714710 23331499 7687739 21071413 10339576 125919597687739 25772309 1309608 9582367 27192911 12591959 10950949 11121055 8663044
FGFR1 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
FGFR1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAPK1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27342992 23405013
MAPK3 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27342992 23405013 18411303
FGFR1 SYNCRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12601080
FGFR2 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR2 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22726438 19735729 26103942 20554525 23420874
FGFR4 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
FGFR4 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR4 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR4 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 19901323 10918587 9305919 8272872 12626508 16497976 15592455 17389395 12576423 11350938 11294897 12244095 9083098 8626374 9566874 11940572 11429593 14551213 11850821 17016520 9582023
SYK FGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11672534 15536084
FGR PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 32051585 27790061 12590707 28692661 14610060 15728464 12495636 28377405 10593973 16510472 11369622 14603053 26710849 9148935 20160475 29743287 24608426 12408869 14572662 24655477 26530902 34237080 11438458 12659633 26068982 15126359 14978737 18676832 27270311 12023386 11331870 15800067 23109003 7597091 33674746 8051157 11891289 22761432 19962670 20180147 24858039 11035755 10753828 11857088 15611137 7529876 15389641 33715263 15077193 17234784 8824286 34161758 10821872 12754219 12087088 15316068 22751010 32049010 12531888 12387730
FGR SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11162638 11078745 11744621 12096713
PAK1 FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 18598695 18088087 24278701 12198493 26009991 15024089 25472536 23246867
PRKACA FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15228085 15024089 207708 17564427
PRKCA FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12704190 21807941 24309511
FLNA MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9006895 20156194 23331499
SYK FYN â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10358164 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23609447 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615
ITGB1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
LCK FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
HMGB1 FYN â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12646658 15802534 19931333 22842346 26618107 27048821 27192565
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FYN PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 25241761 11927579 10383400 8621384 28259175 12721299 18387943 10319993
FYN PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 11369622 12558988 15494733 20151426 12590707 16293639 7505391 15728464 11278857 16713569 10753828 15494732 10085136 15494734
FYN SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7797565 7513017 17570479 10477689 9535867 16713569
FYN WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 18083107 25709608 7565724 8805332 10224664 18088087 19690332 12431372 12235133 16713569 15592455 10532312 14707117
FYN SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12893833 11162638 11744621 28671665 17570479 16713569 24860424 11078745 12096713
FYN ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7760813 16713569 16839418
PRKACA GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12399457
SYK GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
WAS GRB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11340081 11829459 10878810 12213210 11553796 10781580 11157975
GRB2 RAC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 RAC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
ZAP70 GRB2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
LCK GRB2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
GRB2 SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 ITGB1 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
GRB2 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
MET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9660480 15546961 22128289 12475979 11063574 7511210 11439336 8662889
SYK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11964172 16189514 22267732 10747947
JAK2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8536716 8950973 7500025 17474147 19273609
RET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9393871 16189514 15677445
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
GRB2 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10087612 20936779 27107012 10781580 25416956 21706016 16713569 17474147
GRB2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12522133
GRB2 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 10806474 12558988 8649427 8816475 11119718 16298995 7597091 7997267 9148935 12110680 12005431 10085298 16713569 10749687 10354709 21900206
MAPK3 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24089523
PTPN1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 11884589 15976035 8702689 16926280 8999839
PRKCD IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11884618 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
SRC IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17389395 15212693 18691976 7559478 7493944 7537849 20068231 23472139 8550552 17016520 8940173 9480911
IGF1R PDPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20044479 11054117 17570479 20643654
PRKCA IQGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 27815503 21349850 25618329 15695813 25733387 28739799 15355962 31474712
IQGAP1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11319218 8226933 1330321 16135787 17563371 7992057 8248196
IQGAP1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15655247 11319218 8226933 1330321 1497021909368021 16135787 17563371 7992057 8248196
IQGAP1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 31980649 28007913 8798539 19079338 9199170 8670801 8702968 15695813 15217908 8756646 18809683
ITGB1 PTK2 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
PRKCA ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12138200 12435334 20926684 11700305 10592173
ITGB1 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8649427 21909923 8878413 10545505 7657702 9003039 19339212 19487819 19161977 16189514 16919435 7529872 19889638
SRC JAK2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
JAK2 STAT3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 11867689 14610620 19833085 20237318 20406969 20581311 21840487 22754783 24091328 27216177 7512720 7521688
PTPN1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 18988627 15780598 15821101 12748279 11694501 11970899 11970898 21806020
JAK2 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 167.0 1.0 Omnipath 10918587 8272872 16319070 18718905 15592455 34066153 23166634 33986510 17389395 29162862 29449694 33512408 21098725 9083098 17565041 27748760 27344175 34031055 29290793 21285325 33846242 33774038 9566874 25962054 20826784 14551213 26188635 26008966 15284024 26175413 21481791 33774344 26307676 9305919 10925297 15615703 12626508 16497976 32087696 16469875 31914141 23331499 11350938 28978186 16306356 33824475 18988627 17401459 19147545 15151905 12637586 34433042 8626374 15950906 27181202 24793791 20455003 21575192 32094172 15322111 17016520 34247191 19901323 12626585 27086926 21166956 23906537 31976162 9211920 12576423 22306293 10207096 12075083 11294897 26787900 12244095 14701810 33909625 11803465 17360477 28827891 33820781 19159681 18939995 11445068 27941883 11429593 30054295 26675255 11850821 9582023 34067421 34707127 15786731 25986861 27351213 34118143 15077188 26699492 12595539 21071413 18498667 22153071 15156153 33513694 25915428 11940572 12529382 18525315 24501689 33839684 24316223 19834108 9575217
SRC KCNA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11812778
LCK ZAP70 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
MAPK1 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 8506364 7499846 8618896 15967991 8226850 8626561
MAPK3 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 8506364 8618896 8226850 7597029
SYK LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 8798764 19664994 15536084 8621719 8798676 16497976 25990959 7518561 8845015 16189514 7539035 15659558
LCK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11404481 9484840 9344858 18070987 10815799 16189514 10825200 25814554
LCK PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17389395 18691976 15541367 10319993 19144319 16497976 15133032 17016520 11381116 15302935
LCK ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 23874979 7961936 17579062 29073235 30992398 15292262 23933134 31932281 21829558 15592455 21917715 9199177 8798643 7612267 16339550 23331499 10202147 22238573 16189514 32184287 21103055 7642520 33531381 12648457 12522270 17998387 9685404 20945976 16839418 15144186 16461343 16094384 11270871 17192257 10037717 8756661 19606965 23758320 27869819 16111633 25137454 15268851 17942891 33482200 11514606 11514605 15659558 10556826 10318843
LCK PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11369622 12590707 15728464 9257837 10753828
LRRK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20127702 22924508 22658533 24907399 19576176
MAP3K7 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
RAC1 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
TGFBR2 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11274345 12738796 14557817 15265520 15282297 16200688 16474430 17934056 18855897 20060931 20519943 21614932 22703233 23070005 24132110 24336330 24403530
RAC1 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17496910 18000759 15574420 19151919 10727406 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353 11562357
MAP3K7 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 11477091 17301840 13130464 18855897 15125833 24699077 9278437 17363905 18641653 24403530 20060931 21133840 21614932 9891069 12738796 21232017 9851932 18264787 10391247 16799562 23109003 12620219 14633987 12709432 8177321 19161412 22941947 23681101 12556533 11280761 15082531 26192618 14660645 24958845 20164171 11460167 16603398 21041997 11274345
MAP2K4 PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11335711
PRKCZ MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
SNCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11279280 12121974
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
RET MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 19901323 11522789 91184134 16156666 16497976 15592455 12571246 19415658 11826406 17389395 18578522 21109534 20068231 18452278 18669648 16153436 11522288 18691976 1378617 15972258 15935618 16094384 12388769 11971971 19651622 21842857 28450419 18707149 17016520 21455180
MAPK1 NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17570479 8626435 16778989
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 12054624 15547943 20080742 14967450 12040186 15173823 12697810 11940578 7545671 16227978 21035469 12738796 16039586 9722592 17255949 15774499 15187187 19541618 19091303 19565474 17052211 19085255 11279232 9271440 18039929 18775330 11705993 10601235 12792650 11431469
MAPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8939914 12832467 9915826 17906627 32296183 19282669
MAPK1 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15950189 22028470
MAPK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 59.0 1.0 Omnipath 18448488 19413330 11335711 9343414 15465816 25584415 12576423 11350938 20068231 12681450 12763138 9872331 11780390 18491316 18669648 11404481 10521505 18691976 20058876 15979846 14551213 10446219
MAPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19604315 15542607 16964243 15212693 11604394
PRKCA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
RET MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 551.0 1.0 Omnipath 15956760 25485910 17240116 20385359 12527803 17621270 23612968 18212246 21860413 18097051 18851832 10645003 25679764 21423210 15007380 19934253 19935718 22356909 9677429 15781651 10849428 17188005 20667468 14625304 34380633 17377139 21423211 20010870 26186445 20736304 12376318 33627405 16740736 21561860 15004239 17901130 15212956 15897464 15143154 18819921 17157789 26297582 12138104 11777927 22158866 23195225 34473994 20494825 14963038 16778204 17391526 27683117 22689060 12444552 31933886 15059947 26823016 15657432 19377875 17142325 15486045 21460222 23431142 11159838 27654866 19941816 14718389 34375550 18593598 17360704 23997214 24501773 16163708 10604992 15297577 17106060 24396487 25893857 20361349 16822962 12554776 18454177 29434871 34530870 16141331 12356731 19169277 20543098 17685427 21478906 18463290 16250012 20534535 21228323 7535768 26617336 15963258 10617652 17196532 19995915 10464310 15315965 12082540 21685939 25730857 18305109 25703330 16928771 15681433 11083859 16076871 20395206 23146907 26246800 21454539 12660819 21220474 15866871 15637081 19858202 34403210 18032526 16195541 21829454 16459330 17209045 12808105 11585739 16162500 25833830 18246127 11864968 24418169 15935618 19925796 20160123 17056593 14998784 18215133 10508618 18775330 18760948 12952943 21768338 17317777 8155326 22258404 15788397 26919095 28213521 21192818 33798093 15851026 26242183 12402043 21868357 17064352 20927383 16380505 15035987 21454675 18957207 19193766 21188622 19050043 16904111 19888469 26073130 20185553 15282551 16790523 23405013 11994288 17510392 32081857 18941537 20930115 19106095 11043579 21499301 20145126 24427291 10958690 15939799 19088846 19286657 18424438 15308678 18198175 27323814 24338688 24252946 19956644 21478903 12014987 23017243 17525129 12511559 17615152 16505244 20122898 12077249 17123942 26035354 11278407 15665049 20531297 17292825 14976148 16449644 16461767 23361053 19261611 11502744 25658205 12149254 30327409 17560175 24352879 26586479 26804906 25779944 34125833 19118012 11352917 16740725 11884401 16464862 16641227 27323830 18063582 22955283 24561529 10779765 10542198 16135812 23564461 17210721 24469048 24803537 21602434 17110601 21045017 11073973 10597231 23687376 34556812 17341659 18692468 17579083 12384403 21408150 25417160 11752053 23325789 17371847 11970985 22327338 26265441 16840783 17283152 26616862 23188829 17239630 21487005 11024037 17053147 24363437 25682201 20234004 12391272 23644655 25638159 20808799 17922836 20129247 24913355 18451171 25483104 26296889 21081844 17404396 11287604 18263590 26317416 15541367 16467309 12765939 16331263 16498402 20485667 11230338 16387841 19543320 7687743 20228268 15630487 16774943 16710359 10803464 16844778 16574647 15994317 17495961 21215800 17590453 26382850 19002495 12909616 20599567 12558965 10667594 24711455 17255109 16038803 12370087 21072043 20008839 18805968 10206983 11875080 20231899 21499296 21908610 16002410 12821943 24292678 17525735 17928416 21057531 25236495 17283137 21659545 24403530 16919488 23378338 22973961 18847491 16682955 20840866 16153436 23542175 24492000 12526087 26556867 12133965 12433918 20065107 14610044 11959800 15580310 21730285 11046056 9124279 14707024 26725216 16452220 22212957 25811962 15696170 11416124 20498373 17157787 21653826 16149052 20022946 34262144 16434970 10558990 18045996 10925301 16280323 25581518 15899879 21441955 20566643 15466476 15657177 11706017 15059847 8444886 18519681 23528009 33513601 20138986 12368275 24608435 17062641 20082306 20375017 17537990 24567333 33820494 10712263 21278199 19011679 20145145 27582276 25640183 21730054 16177091 17250586 15879307 16728403 18299328 24269888 17303383 9482941 17671177 17173941 24095720 15304500 12874275 33828192 11827968 33731431 10799542 15328343 18838481 19036157 17634226 17110082 17855349 31722981 26079947 25002506 14559232 23584478 18593910 17114467 16373398 16931794 17016429 14676826 28415597 12029087 24269383 8626767 20478260 12097262 14764579 12181310 15100319 12384432 15271996 17562849 19036927 19326083 20072652 25940440 11922392 17913704 19494114 25596730 18938240 27449290 12897059 21478911 21123455 26804170 10940302 16624816 26876209 12048182 17150968 21478863 17307705 18658095 24995980 16582879 17289590 33667549 17209041 17890097 21726627 27662093 16843264 19426503 11103941 11940578 17906618 26234813 19029090 15007386 15958730 12576312 17667937 17785202 34480897 20647329 18941890 16446383 25562429 10867021 26985018 16413470 23178720 25578563 34437586 21738699 21258408 20388777 24681954 20459645 12242309 15289328 21575862 16185843 19147767 34497368 19153083 12124352 17371994 17567959 15611080 17297454 23012246 14557270 28542650 15713673 21129803 19460345 10958798 21772273 21900206 19205871 17591920 19217381 12963813 19718025 24469056 16624867 21149447 15728578 33902596 11971971 16455819 19112174 10751321 1835084 11016927 18267069 20410276 21980390 17409387 23831578 21477078 15558056
PRKCZ MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK3 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20041225 15950189 21738525
MAPK3 NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11485312 11535139 8626435 16778989 7520867 15629715 94375440 8089108
MAPK3 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 15547943 20080742 14967450 12040186 15173823 12697810 11940578 16227978 12738796 16039586 9722592 17255949 15774499 15187187 19541618 19091303 19565474 17052211 11279232 9271440 18039929 18775330 10601235 12792650 11431469
MAPK3 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 23602568 8939914 12832467 17906627
MAPK3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 18448488 19413330 11335711 9343414 23331499 15465816 25584415 12576423 11350938 20068231 12681450 10417333 12763138 9872331 18988627 11780390 18491316 18669648 11404481 10521505 18691976 19723038 20058876 14551213 10446219
PRKCA MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 17496910 11940581 21386996 15075332 11447289 19615955 8294430 16488589 6321473 8321321 12845332 11313945 17570479 94124523 12040186 19568798 15567848 14585353
PRKCD MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17496910 11940581 21386996 7925482 15075332 11447289 19615955 8294430 16488589 6321473 8321321 12845332 11313945 94124523 12040186 19568798 15567848 14585353
PRKCZ MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 15075332 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
SRC MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 24728074 24034250 9837958 17570479
PTPN1 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18579758 16537444 22789536 18819921
MET PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15611085 29435030 30134553 22188814 24043698 16782899 14572662 15247219 15561106 20802513 15598735
MYH9 WIPF1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10467124 10511705 11395419 11520460 12177428 14707117 15001467 16293614 16606694 17890224 19349987 19741094 21178402 21840487 22166994 23212475 23725295 24857661 25712372 8625410
MYH9 WIPF1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10467124 10511705 11395419 11520460 12177428 14707117 15001467 16293614 16606694 17890224 19349987 19741094 21178402 21840487 22166994 23212475 23725295 24857661 25712372 8625410
MYH9 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PAK1 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10092231
PAK2 MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 2160950 18088087 10748018
SRC MYLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12408982 20861316 11113114 10362724
PRKCD NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8626435 17069809 23109003 12734380 96198102 16297854 9857051 11145703 7657821 10336447 12056906 94375440 8089108
PAK1 NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12855698 7618083 16099876 10559253 18160398
PRKCZ NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8626435 12734380 96198102 11145703 12056906 94375440 8089108
PRKCA NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17069809 9857051 11145703 23085266 24632950 17570479 23002436 17217339 23119229 8626435 12734380 96198102 94375440 8089108 24970888 15657040 7520867 31736979 10559253 22460559 12056906
PAK1 NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 10026169 25416956 10592173 31515488 11557983 32296183 16713569
NCK2 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10592173 11950595 16713569
NCK2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26186194 10026169 25416956 10592173 31515488 11557983 32296183 16713569
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
PDPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11134074 21726627 21209852 10995762 23885116 26009991 26238471 10551809 25335797
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
RAC1 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 8107774 10023776 8805275 9744077 23331499 8910277 22705156 20936779 9535855 19264842 19628037 11728826 20696164 16212495 12480336 11152757 9823899
SRC PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16374509 12215529
RAC1 PAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9744077 10023776 8805275 16212495 12480336 11152757 25301945 11728826 11478794 8910277
PDHA1 PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK2 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 40.0 1.0 Omnipath 12676647 19415658 17081983 82003483 20166139 18767875 17474719 18691976 22910903 11485553 11486000 7782287 19341700 16436377 7273851 18212344 15302935
SRC PDPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20643654 14585963 16314505 11481331 15212693 12738763 1148133 15302935
RET PDPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16314505 11481331 15212693 12738763 15302935
PDPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19369195 10480933 17192257 17906627
PDPK1 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12887331 14500673 11222751 18691976 10075713 20332120 9768361 9748166 17335005 10357815 16189514 11141077 16051884 11781095 10764742 14604996
PDPK1 PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15209375 11078882 10698939 9889098
PDPK1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 17081983 12429015 15208671 18326039 16286006 11438723 21561857 18802401 19864428 16099428 7545671 7489717 27149630 15388791 12183455 10601311 9465032 26582459 29257917 12967624 24604594 15718470 9427642 10209156 23769967 12586835 15809305 9218810 11500365 14560963 9271440 20932932 12370290 11914378 11684675 17680028 14993219 19570988 9445476
PDPK1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 16026785 20732331 15481030 22493239 10698939 9707564 8706898 20137943 21774789 17192257 22154087 20481595 12372837 16765046
PDPK1 PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 16505477 21310943 11839738 31511386 9748166 25472878 25755284 15811957 15133032 11781095 19664995 15024053 15302935 15949469 14581488 28784722 17570831 18669648 11381116 20058876 17965192 19632318 20501830
STAT3 PIM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10068671 18426800 17717068 22273698
PRKACA RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20682772 15966897 17050626 11886862
PRKACA STK24 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10644707
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
PRKCA RAC1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10679481 10871288 16492141 18851840 20027184 21474067
SYK PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9531509 20068231 12881490 17192257 15583006
PRKCA PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15212693 18337243 11741879 11948398 17570479 34010649 10197446 10867018 15024053 15383279
PRKCA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16628218 20027184 11284700 18851840 21474067
PRKCA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 17496910 11940581 21386996 10527887 2996780 11447289 19615955 16488589 6321473 8321321 12845332 11313945 2136766 17570479 12040186 19568798 15567848 14585353
SRC PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15851033 14970215 17569658 19366211 26876198 27203386 15961393 24211614 16982614 17570831 23329791 23329794 15541367 18550549 22689788 28637715 14715667 29422059 17658731 10319993 19138410 11927579 29452094 19632318 15337529
PRKCD RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20041225 15950189 19059439 21738525
PRKCD STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 76.0 1.0 Omnipath 8272872 19413330 11335711 15677447 9343414 15465816 8140422 12576423 11350938 7678052 20068231 12754507 9880505 12763138 9872331 18491316 18669648 8662591 10521505 18691976 27036017 27458446 7537214 8626374 20058876 25280942 16951338 14551213 8164674 12754506 10446219 12361954 12754505 16418226
PRKCD PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15212693 11741879 11948398 23109817 21726532 10867018 15024053 15383279
PRKCH SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 8621384 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCH PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11741879 11948398 10197446 10867018 15024053 15383279
PRKCZ SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 10527887 11447289 19615955 16488589 6321473 8321321 12845332 11313945 16189514 12040186 19568798 15567848 14585353
SRC PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12637538 28174535 28842658 17804414 12505989
PRKD1 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8885868 20956537
SRC PTK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11476890 12531888 16919435 17496910 17517963 20027185 25572304 26552706 27216177 8892616
SRC PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 216.0 1.0 Omnipath 27351421 23242524 16254240 12370821 21940449 26142360 17525734 10593973 14604860 17389395 19171305 22402981 19339212 22353809 9748249 8941336 17570479 12464388 25226367 15611085 15817476 25241761 26393679 27978555 26833789 11927607 17828307 25913180 26866924 15247219 10085298 12387730 19055942 9507031 21454698 10973994 32814053 21057587 27931517 27438371 18793427 19695571 15735019 18560762 10592173 25319025 24389213 21852560 26689988 14984767 7505391 19568240 20103658 20822514 25868388 23275294 28423510 23764511 19625610 15561106 17192257 19138410 19369195 17088251 12753909 28701735 29190494 17016520 15598735 18814847 11821402 11418135 15728464 16291744 25067788 11602246 16713569 22287273 9032297 7997267 12960434 11369622 20616959 26079101 19534553 10931187 22710722 20068231 25866790 21347260 9822703 28202937 16153436 11980671 21855630 19826415 18464795 7529876 20621036 9330873 21473875 9425168 28956212 12615911 15951569 25814554 12876384 17438336 15212693 16966330 20705914 20847951 23729178 20407018 12558988 25127991 25918719 12590707 16360410 8054685 18814027 11696015 22800863 17117420 12495636 11278488 9864370 21776383 18083107 22814579 22194915 20515733 11119718 9148935 10428489 15743500 20655298 23065768 28213315 26923073 24015220 17289681 12110680 22006118 24164353 23109003 18935208 10753828 18233957 8816475 25118939 19664994 25530216 16760434 9330875 21266176 21034468
SYK PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9169439 9342235 16189514
PTPN1 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9418872 16291744
YES1 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11369622 12558988 16293639 12590707 25868388 15728464 25416956 32296183 10753828 23397142
RET PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 9507031 21454698 11696015 14739293 28416479 34169835 18083107 11313859 12960434 17389395 12927054 29535802 19534553 19339212 20068231 21852560 25817040 16153436 25868388 11927607 15561106 17192257 7529876 23637231 15123632 19369195 11839732 19664994 16126008 15247219 11027591 15951569 17016520 12387730
PTK2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 22163037 26816343 29036929 34252134
PTN SDC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28356350 25620911 11461706 8175719 16713569
PTPN1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15821101 23331499 11970898
PTPN1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 10698938 25585026 17092689 17974954 16537444 18332219 9600099 15866871 8647855 9261115 11346638 12857726 12468645 11007774 1646596 16115959
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
RAC1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 26430964 16189514 11021801
SRC RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11713247 17570479 16189514 10070972
RET STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10918587 9305919 8272872 12626508 15592455 24662939 23331499 17209045 12576423 11350938 18498667 11294897 12244095 16189514 25047660 17761947 9083098 25241761 12637586 8626374 15485908 9566874 11940572 11429593 14551213 11536047 11850821 15212693 9582023
SRC SH3PXD2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24174371 19596797 20943948 9687503
SYK SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 12893833 11162638 11744621 11078745 12096713
SRC SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15212693 12893833 11162638 11744621 28671665 24860424 11078745 12096713
SRC STAT3 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 16472776 17192274 19930715 22131018 22677902 23589069 23691193 24030100 24403062 25687758 27036022 27452906 29556339
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
SRC SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7513017 17353363 17570479 16189514 9389695 23100514
SYK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10777558 25416956 21516116 20133729 31515488 16189514 10825200 32296183
STK24 STK38 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12493777 16314523 21262772
STK24 STK38L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16314523 15037617
WIPF1 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16582881 10087612 16055720 12372256 10878810 11331876 25416956 23414517 12437929