Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EGFR ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24797263 20029029
SRC PXN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574420 14665621
IQGAP1 PXN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15263019 22573807
PXN FN1 â—¼   COLOCALIZATION 2.0 0.8 intact 21985969 8208414
LRP6 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 16273260 23371553
DVL2 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
DVL2 RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11779461 18162551
LRP6 DVL2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 16273260 23371553
PRKCA VASP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14706852
VASP ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 1318192
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
PRKCA ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15590896 10592173
ARPC2 ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 9600938
ACTB ARPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 9600938
CFL1 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CFL2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SRC ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
ACTN1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
AKAP2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PRKAR2A AKAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218560 16642035
PPP1CA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8288823 20186153
PRKACA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA AKT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288823 20186153
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
ANXA2 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ARHGAP21 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15793564 32203420
BMX ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
BMX EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
BRAF PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
PRKACA CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
CDH1 TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDH1 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0710504105 18093941
MAPK1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17205132
CDK1 PRKAR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9852131 1918018
CDKN2A CDK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
NFATC2 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12453415
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
CFL2 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MAPK1 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
MAPK1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8941362
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
RAC1 CYFIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9417078 16189514
SF3A2 DDX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
HNRNPK DDX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
DDX17 RBM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
NUMB EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221644 9303539
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
ESR1 PPARGC1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 18511507
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
SAFB ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10707955
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
PRKACA EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12840026
FN1 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11476890 16919435
PPP1CA HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17008050
PRKCA HDAC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8307255 21952047
HNRNPK HNRNPA0 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPA0 SRSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPA3 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SF3A2 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3B2 HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RAP1A HNRNPDL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPDL NONO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC HNRNPDL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12695333
SRRT HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RBM4 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPK RBM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPK MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8349701
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
SHC1 IQGAP1 â—¼   COLOCALIZATION 2.0 0.8 intact 7714573 20075861
S100B IQGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12377780
MAPK1 LIMA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23188829
SPTAN1 LZTS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SAFB2 MAP1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
PRKCE MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11350735
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
PRKCE MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16810323 16461926
PPP1CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
MYC TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NFATC2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23858296 22333584
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
SF3A2 NCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
PPP1R9B PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PPP1CA S100B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKAR1A PRKACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 24855271 1252328
PRKACA S100B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKAR1B PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 26687711 32296183
PRKCA PRKCE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
PRKCA SHC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7929214 12052829
RAC1 PRKCA â—¼   COLOCALIZATION 2.0 0.8 intact 5218533 16628218
RAC1 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
SRC PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
RAP1A PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11476890 16919435
PTK2 SPTAN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12700044 2809592
S100B RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SHC1 RAP1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10964917 8755247
RBM4 RBM10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SRC RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 23027962
RNF113A SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SRSF1 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3B2 SF3A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
SF3A2 SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SF3B2 SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SHC1 TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731794 17440088
MFAP1 SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
NUP35 SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPA0 HNRNPA3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPH1 SAFB2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPDL HNRNPL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPL RBM4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CPSF4 SAFB2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SF3A2 SFPQ â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SF3B2 SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SAP18 SRRT â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPH1 SAFB â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SF3B2 SRRT â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPA1 SF3B2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DDX17 HNRNPL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SAFB SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPK SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PPP1CA TOX4 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
SNRNP40 SRRT â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MFAP1 RBM14 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SAFB WTAP â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ACTR3 ARPC3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPH1 SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPDL SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HNRNPK SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MFAP1 SAFB2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
MFAP1 SFPQ â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HNRNPA1 HNRNPDL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DDX17 SAFB â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SAFB2 SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SAP18 HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 9150135 16189514
SNRNP40 WTAP â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
GATAD2B RBBP4 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
HNRNPA0 HNRNPA1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPC HNRNPK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA3 SF3A2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
NONO RBM14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CPSF4 SF3A2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPDL SFPQ â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
NONO SNRNP40 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPC WTAP â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ILK PXN â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
PPP1CB PPP1R12B â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
SAFB2 SRSF1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SAFB SRRT â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA3 HNRNPK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA1 MFAP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MFAP1 SRRT â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CDH1 SRC â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
HNRNPK RBM14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA1 SRSF1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ACTR2 ACTR3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPL KHDRBS1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPC SAFB2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
NCOA5 SFPQ â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA1 HNRNPH1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SAFB2 SAP18 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPK SAFB â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RBM14 SAFB2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SOX2 MBD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24048479 21532573
MBD3 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24048479 30415952
RAC1 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC MFAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
VCAM1 VASP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
TMOD3 SVIL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SVIL ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 11792840
SVIL ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12202484 34079125
LRRK2 ABCE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
STAU1 ABCE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23125841 30948266
STAU1 ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15121898 23125841
EGFR ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
VCAM1 ACTN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
VCAM1 ANXA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MYC ANXA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 30081903
LRRK2 ARPC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20876399 31046837
VCAM1 ARPC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
BRAF RPTOR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
MYC CBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CBX1 RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
VCAM1 CD2AP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MYC CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
VCAM1 CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CFTR STAU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CFTR DAB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20351096 17110338
CFTR EXOC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
VCAM1 CLIC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ESR1 CLIC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
TMOD3 COBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LZTS2 CPSF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC DDX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
VCAM1 DDX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
STAU1 DDX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29374155 23125841
DDX17 SFPQ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34133714 26344197
NUMB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16273093 25754235
EGFR LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24797263 31980649
EGFR EXOC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25594178 23956138
VCAM1 EPS15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
FLII ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 14966289 19720835
ESR1 RAP1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
TMOD3 FLII â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VCAM1 FLNB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HDAC1 STAU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30948266 19293945
MYC ILF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
VCAM1 ILF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
LRRK2 SF3B2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 RHOA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21454543 31046837
MYC SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC SF3B2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC MYO5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYL6B RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 31871319
TMOD3 MYO5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TMOD3 MYO5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SFPQ NCOA5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VCAM1 NONO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RAC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SOX2 RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23667531 21532573
RBBP4 RYBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30217970 34316702
VCAM1 RBM14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RBM4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SAP18 SRSF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22939629
VCAM1 SFPQ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
TPM2 TPM4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22939629
RBM14 SF3B2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPA3 SAFB2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SF3A2 SF3B2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MFAP1 SAP18 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPA3 HNRNPDL â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPDL SRSF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 SAFB â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
KHDRBS1 SFPQ â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 SNRNP40 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPH1 HNRNPL â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
SFPQ WTAP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SFPQ SRRT â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPC SRSF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 HNRNPC â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DDX17 SAP18 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SPTAN1 SPTBN1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SFPQ SRSF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CBLL1 WTAP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPC SRRT â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPL WTAP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ACTB SVIL â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CPSF4 SAP18 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CTNNB1 CTNND1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
SAP18 SNRNP40 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SAP18 SF3B2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SAP18 SF3A2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 HNRNPA3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ESR1 ACTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23403292 31527615 19805454 21182205
AKT1 MAPK14 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
EGFR ANXA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25136068 26320552
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
STAU1 ILF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29395067 26186194 23125841 30948266
MYC NONO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 29467282 17314511 17967896
MYL10 MYO19 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SAFB2 SF3B2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPA1 HNRNPA3 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
MFAP1 SRSF1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPC SF3B2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPA1 SAFB2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CPSF4 HNRNPL â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPL SF3B2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RBM14 SAFB â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
DDX17 SFPQ â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HDAC1 SFPQ â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DDX17 RBM14 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RBM14 SF3A2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPA3 SF3B2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
BRAF MAPK1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HNRNPH1 HNRNPL â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
NONO SFPQ â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CPSF4 HNRNPA1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPDL SAFB â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CBX1 CHAMP1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SF3B2 SFPQ â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
MFAP1 SAFB â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CFTR SVIL â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
MYC ACTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29467282 11839798
SRC BMX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16189514 10688651
EGFR CD44 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23265944 12093135 16565089 15597342 11606076
SOX2 CDK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23667531 30297536
PEX14 DNM1L â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21525035 34079125
EGFR EXOC7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25594178 25754235 23956138
KHDRBS1 HNRNPA1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24514149
LIMA1 TWF1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
PPP1CB TOX4 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
PRKACA PRKAR2A â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HNRNPL RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA3 RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ACTR3 ARPC2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPK HNRNPL â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPC SNRNP40 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA3 SRSF1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CAPZA2 S100B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CPSF4 RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPL SAFB2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
MFAP1 SF3B2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA1 SNRNP40 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RBM14 SAP18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPC RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA3 SAP18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
SAFB SRSF1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA1 RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPC MFAP1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTR2 ARPC3 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PRKAR1B PRKACA â—¼   PHYSICAL_INTERACTION ✅ - 0.84 0.84 Signor 26687711
SAFB2 SFPQ â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTN4 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21078666
CFTR LMO7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
CFTR CLIC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR LIMA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
CFTR TMOD3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
CFTR FLII â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
ESR1 NONO â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33731348 25604459 31527615 20348541
SAFB SAP18 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPL SRSF1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
ARPC2 ARPC3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CREBBP KHDRBS1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HNRNPK KHDRBS1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HNRNPA1 SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPC SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA3 HNRNPC â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
SAP18 SRSF1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPK SFPQ â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
HNRNPL SNRNP40 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA1 SAP18 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HDAC1 WHSC1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
HNRNPL SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
SAFB SF3B2 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA3 HNRNPL â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
LRRK2 DVL2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31046837 19625296
SVIL LIMA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 20309963
LIMA1 ACTB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
ESR1 DNM1L â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 19805454
HDAC6 ERBB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20029029
ESR1 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 16651450
MYC EXOC4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29467282 17353931
RAC1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21454543 31046837
ACTG1 CFL2 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
EZR MISP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
HNRNPA3 SAFB â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
MAPK1 SHC1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
SAP18 SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CYFIP1 NCKAP1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SFPQ SNRNP40 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SF3B2 SRSF1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RBM14 SNRNP40 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
SAFB SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
HNRNPC HNRNPL â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
HNRNPH1 SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
TMOD3 ACTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 34079125
COBL ACTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 34079125
ESR1 ACTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20308691 19805454 21182205 21182203 31527615 20348541
LRRK2 LRP6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22899650 27013965
STK4 MAP1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23455922 24366813 20562859
SOX2 SMC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
HNRNPA1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPA1 HNRNPL â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPA1 HNRNPC â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CTNND1 EGFR â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HNRNPA3 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CPSF4 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
RNF113A SF3A2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAPK1 MAPK14 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RHOA SMURF1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HNRNPL SAP18 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPC SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PRKAR2A PRKAR2B â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SF3A2 SRSF1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ACTB CFL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HNRNPC SAP18 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
GATAD2B HDAC1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
PPP1CB PPP1R18 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
SHC1 SRC â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
RAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21217774 16331275
CFL2 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8153045 21516116
ACTN4 MAGI1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12042308 16713569
ILK AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11825911 11546794 11313365 18339839 11278835 12149249 14500673 9736715 12176337 11445557 16189514
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
DDX17 YAP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27684187 31501420 24581491
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
HNRNPA1 HNRNPL â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MAP1B LRRK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21159966 24754922
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EGFR EPS15 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CBLL1 CDH1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
COBL PACSIN3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NCKAP1 RAC1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PRKACA PRKAR2B â—¼   PHOSPHORYLATION ✅ + 0.88 0.88 Signor 15187164
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
EGFR ARF6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34079125 24797263 31980649 20029029
EGFR ACTN4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 26320552 25402006 24658140
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
CD44 SRC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21701559 11084024 9519902
MYC CDK4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 21988832 28628118
DAB2 SRC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12473651 16713569 16189514
DDX17 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15298701 16189514 19995069 20663877
EGFR HSP90AB1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RAC1 IQGAP1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 18809683
ACTR2 CORO1C â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RBM14 SFPQ â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
ACTG1 CFL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
NONO SFPQ â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
KHDRBS1 SRC â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
HNRNPL SFPQ â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
SAFB SAFB2 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
AKAP5 PRKAR2A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ERBB2 SRC â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MBD3 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 17827154 24048479 26344197 21258344 16428440 12354758 28514442 27068747 19041848 10444591 25123934 12124384 23752268
ARF6 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17363898 16452216 15210957
ARF6 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17363898 16452216 15210957
MYC MFAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
EZR ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 7876308
MYC ACTG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PTK2 ACTN4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23454549
AKAP5 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1512224 8599116 10939335
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
PPP1CC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14633703
AKT1 HNRNPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18562319
BRAF MAPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
BRAF MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
PRKCA BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1386920 16810323 12917261
MYC CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22002305 22911891 19738061
PRKACA CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16785995
EGFR CDK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18271526 15657067 24658140 31980649 23956138 25402006
NFATC2 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12453415 11402342 11030334
ILK CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18252715
PRKCA CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11463380 17570479 20577053
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
PRKACA CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22798526
MYC CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10229837 11145693
ESR1 DDX17 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11250900 25604459 19995069 20663877 21182205 12738788 20348541
DIAPH1 ERBB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
LRRK2 DNM1L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24282027 22228096 22639965 23813973 29541021
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
MAPK14 EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24269888
SRC ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 19704002 21075308 7542762 7797556 19372587 29720121 11940572 17875712
SHC1 ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30898150 10085134 9019162 24658140 22973453 16729043 9710588 28065597 16843263 9756944 16713569 16273093 8665853
ERBB2 RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
MYB ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2577338 7721862
SHC1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
SRC ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17043237 17284441 17400812 15604093 11032808 17921256 18451880 15020686 12736255 11564893 23065768 10454579 20935677 17363140 16957778 14963108 11013076 29720121 15784253 24498420 17627277 12630920 22328528 14766010 24051437 7539106 27420286 15140878
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
EXOC7 EXOC4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27173435 26344197 12687004 22939629 12738960 21241894
MAPK1 EXOC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22595671
RHOA EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 35267019 15659383
EZR PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11468295 16189514
FBP1 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FBP1 PTK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FN1 SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
FN1 RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
HSP90AB1 GTSE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
PRKCA HNRNPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7727389
SHC1 ILK â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKACA LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21262972 18981475 21406690
PRKACA LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21390248 24351927
RAP1A MAP2K1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK1 RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK1 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK14 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15649893
MAPK3 RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK3 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
MAPK3 PPP1CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15930121
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22159222 20383141 22235332
MYC PEX14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC TPM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
SFPQ NONO â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 34017080 11259580 24981860 26344197 22939629 25959826 18042045 31815296 12403470 30725116 21988832 17507659 28514442 30445466 17452459 30021884
PPP1CA PPP1R9B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PRKCA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11284700
RAP1A SIPA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 1846040 15632203 9346962
TGFBR2 SMURF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15496141 11163210 11278251
PPP1CC PPP1R9B â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ACTB CFL2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
ACTB SPTBN2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
PTK2 PXN â—¼   PHOSPHORYLATION ✅ + 0.9 0.9 Signor 15688067
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CDK4 HSP90AB1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
GATAD2B MBD3 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HNRNPA1 HNRNPH1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
MBD3 RBBP4 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ACTR2 ARPC2 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
CBLL1 WTAP â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CREBBP CTNNB1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
CDK4 CDKN2A â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ERBB2 SHC1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
IQGAP1 RAC1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CDH1 CTNND1 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PTK2 SRC â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
SRC CTNND1 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 11382764
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
PXN PTK2 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 25795725
AKAP5 PRKAR2B â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
AKT1 STK4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 19940129 17932490
PTK2 PXN â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
ACTN1 ACTN4 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RNF113A SF3B2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PPP1CB PPP1R12A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PRKACA PRKAR1A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
SHC1 EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10595738 24797263 24658140 7542744 21278788 9130710 28065597 10766863 10635327 8034616 24430869 7518560 12577067 19531499 31959764 8810340 9742218 11196191 23799367 23956138 9756944 16713569 11370743 8665853 18271526 15657067 11408594 20473329 22973453 16729043 20935677 20067773 7506413 16273093 25754235 8610109 24189400 26551075 9388490 8887653 31980649 7542991 9544989 9020193 25187647 25402006 30544639 10049786 8662998
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
RBBP4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 34518534 11302704 11102443 27705803 17827154 10734134 10220385 9885572 10471499 26344197 21258344 12091390 9150133 16713569 11602581 12920132 20127688 9790534 17643391 11470869 19686092 12943729 9150135 28514442 16189514 27068747 10444591 19703393 11171972 15451426 23752268 20585571 9520398 11118440 31435636
SRC SHC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9388490 18840094 9710204 10482988 9096689 7499252 8939605 26551075 16189514
SPTAN1 SPTBN1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PRKACA PRKAR1B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC1 MBD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CREBBP MYB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
AKAP5 PRKCA â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
MFAP1 SF3A2 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MFAP1 SF3B2 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MFAP1 SNRNP40 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
NCBP2 SRRT â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ACTR3 ARPC5L â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
FAF1 VCP â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EXOC4 EXOC7 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRKACA PRKAR2B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTR2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
BRAF MAP2K1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CYFIP1 NCKAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EGFR SHC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC3 ARPC5L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SF3A2 SF3B2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
DIAPH1 PXN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 15866170 16292343 17306570 17575049
MAPK1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10753946 15494312 11784715 14636584
PTK2 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 16298995 26053221 15688067 15572663 15592455 7963537 17389395 25405379 26546726 9658172 15107421 22581436 10823820 16254239 25226367 15817476 10330411 9756887 19543320 9054445 10545505 18707149 29127427 15494312 10764815 7537852 9442086 33823745 12408869 20419088 20655620 22270917 18669648 28373581 10455189 16094384 23936270 19138410 22638989 11337490 11514617 27402964 16713569 7615549 10931187 11774284 26700725 27708220 20068231 20473365 28928239 7561682 34475475 28427224 28068967 8922390 24885567 23209645 27669437 15212693 26711338 9422762 11304546 28214467 26697169 12065577 28415719 10753828 11919182 24364863 9230116 11113628 21741599 10417825 15252114 24642576 22044652 21034468
SRC PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 9636140 28214467 15572663 15592455 16713569 14665621 25795725 7537852 7615549 25405379 11774284 26700725 25182764 15107421 7534286 2472406 12408869 11695992 17570479 10823820 7525621 20103658 16254239 15817476 23109003 27447856 28626446 16094384 18363833 19543320 24364863 28376152 19138410 25323586 27941878 23457577 10085298 22638989 27669437 15212693
PXN ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11694518 11304546 10592173 16936772 17553790
DVL2 LRP6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17234765 18077588 14636582 22411803
PRKCA DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12958364 11940581 21386996 11313945 15567848
DVL2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 15262978 12533515
DVL2 LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 20006983 19625296
PRKACA VASP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 8182057 20058876 20166139 14679200 7925440 8836115 94237860 16197368 10851246 9685341 17287340 10922374 12576312
DIAPH1 ACTB â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
ACTB RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
ACTB CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 8913641 25416956 15364581 10592173 19704022 16189514 31515488 32296183 16713569 29892012 10980704
RHOA ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
RAC1 ACTG1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 18391171 16262445 11231582 9600938 15040784 12743368
DIAPH1 ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
PTK2 ACTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 25860875 20159040 11369769 20940419 16291744 23454549 19229129
ACTN1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 16291744
ACTR2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
RAC1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 RPTOR â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10722653 10949026 11715018 11756412 11923280 15169778 15808505 16697215 17052453 17680028 18372248 18570873 18636226 20138985 20214616 20398329 20832730 9812896
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
PPP1CB AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
RAC1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 20338997 15808505 20138985 20214616 21474067 19568798 15169778 19720745 18925875 10949026 11715018 19143635 12393431 18636226 10617634 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
PPP1CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
AKT1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 19651622 20058876 14688280 11510412 25241761 20230923 20068231 18452278 11410590 17570479 10869359 18669648
AKT1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 27979972 25360797 26804165 28273460 25751140 24101154 25751139 34052254 25362852 28114269 28793266 26265440 31239271 25601544 28474680 33630828 26119935 27144834 27425596 25531778 34206989 34465890 21945154 25195862 31792377 18640976 28775168 32015438 32523092 22234184 33536280 33622361 30600590 24362629 34155345 24658687 21060948 33162394 20153295 26668327 21730131 26549256 21666719 25605730 26039999 34226698 20823509 34516278 27033705 32064037 32271880 32513743 33990468 24812269 32053631 32929029 34058200 25772246 26364602 27765911 26678338 27979971 33552953 28171658 34129887 21376238 28416665 25998128 25109332 12535517 31988076 26933062 26598551 25373897
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 23331499 17680028 20214616 17688959 20398329 16537363 17052453 19575820
AKT1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 22619175 19369195 19737514 19940129 17932490 23431053 11805089 24872389 23893242 17726016
AKT1 VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16551632 19335618 16027165
AKT1 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17554339
AKT1 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 18000759 21157483 11756412 11923280 16697215 20398329 17461779 18372248 15808505 20138985 20214616 19568798 15169778 19720745 17517883 10949026 11715018 19143635 17277771 18636226 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
SRC ANXA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 30081903 15302870 24239898 23594883 18083107 2415974 26716413 17389395 27821486 11106497 88296872 16189514 25574848 25303710 2456953 24727000 17287340 2143014 15212693
ARPC2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
SRC BMX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 27601470 17570479 16189514 10688651
BMX PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 27994061 18437915 21454698 21289086 16291744 22940691 12639965 17117420 23716717 28053086 16920701 16415178 20473329 20658524 21918175 15735019 23466867 17692050 16189514 15707572 20501847 12482769 11909938 16153436 20802517 14656986 15371459 11331870 14645233 16782899 15026417 15561106 14761895 17215324 19815712 25617365 11839772 27226554 29311227 17449913 12871985 17088251 17317726 22490227 12876384 18250445 18664639 32839549 21059620
BRAF PPP1CB â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
BRAF PPP1CC â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
MAPK3 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 14654779 21478863 19541618 21135229 16508002 19933846 15664191 8621729
PRKACA BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11510412 10931830
RAP1A BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12446733 9560161 9094716 11278445 16507992
IQGAP1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14970219 18567582 16135787 17563371 8073291
MAPK1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 14654779 21478863 19541618 16508002 19710016 19933846 15664191 29335436 8621729
BRAF MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 20212043 7706312 25437913 9560161 7936666 14970219 18567582 18332145 8413257 23331499 15342917 21071413 7731720 7873542 26496610 10976102 18988627 17667937 16255777 8131746 16888650 15485920 8394352 15175348 15466476 19541618 25600339 25155755 17563371 16810323 8157000 17979178 18039929 94178255 23934108 7835430 7624324 24746704 16135787 7935374 8039496 8621729
CBLL1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29356040 11836526 22252131 16336960 22715382 19711372 22850631
CTNNB1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18483247 12782598 17724465 10027409
FN1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1730778
MEN1 CDH1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
MYC CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9632747 19176757 23364919 10523846
HDAC1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20580679 19182791 21685935 21184735 24424621 18794357
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
CTNND1 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 7542250 17261850 22752307 9535896 7651399 12707304 23180380 24424122 12640114 11226248 29207493 10225956 12427869 21670201 22850631 20371349 20940130 25468996 10409703 14610055 7876318 22715382 10629228 19711372 8660921 10931041
CDH1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17496910 19029934 22370635 16099633 23343194 19734908 10744074 16039586 22203675 19171760 22007144 19619488 17143292
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
CDH1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17548604 10969083 15662113 31980649 14681060 25241761 24189400 25468996 24658140 25402006
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
ERBB2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 55.0 1.0 Omnipath 18927589 17938195 10770932 17276342 17396146 11836499 17409144 29088738 19276355 26673326 19933706 28335434 20372791 7743995 11322924 19683496 27889260 17466630 14681223 12384528 12049736 7841526 12110582 25744022 18393321 15582998 19861462 14987992 20144215 17466629 16546994 19858290 15136770 14767478 20368335 25994202 10504341 1850698 15350223 24910099 9268380 15296723 8428596 24391510 18469858 8662825 20530684 11782384 15141014 15940258 12766774
CDK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 31980649 8360196 23956138 15901825 28150246 18271526 15657067 24658140 25402006 15302935
CDK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12202491 17145710 17274640 22367880 18088087 17202132 9122166 97225924 10880350
CDK1 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9315091
CDK1 PIK3C2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12719431
CDK1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25971971 8114697 11684694 17570479 12609978
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
CDKN2A CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 17145710 11900540 23602568 9529249 11556834 16161044 17881001 17517622 15065884 9228064 15232106 26496610 10585280 17909018 26186194 17353931 10580009 17955473 10491434 12529334 10719365 28042499 8259215 24855949 8891723 23455922
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
CDKN2A CREBBP â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
PRKCA CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22855535
SSH2 CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11832213 14531860 16713569
SRC CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19802004
PRKACA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 28003367 23060444 25867080 21455600 30600261 1716180 28242698 19328185 32102849 92316961 19095655 14602047 7530719 10581361 11053017 9385646 25330774 15657296 1377674
PRKCA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 92316961 15212693 26888287 1377674
SRC CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10089883 19289168 12237126
PRKCA CORO1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16027158 17350576
CTNNB1 CREBBP â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 10769018 11050151 18160704 15060161 11973335 10775268
KHDRBS1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16713569 12496368 17891136 15021911
CREBBP MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8654374 11073948 12196545 16055500 18585056 16799563 23980173 14761981
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
CREBBP CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10769018 21751375 11973335 17410209 18347063 16476742 23273993
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
MEN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
LRP6 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 25088803 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
RAC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19751508 28626389 26403202 19417647 22270359 16212495 16940750 12480336 11152757 29497040 30650643 19020303 15377999
ERBB2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17496910 7702605 7999105 22558232 14517306 11245482 11950845 12040186 19568798 23576562 14585353 23640056
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
PRKCE CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 27516388 27321178 21251911 32589661 15684660 23542175
SRC CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17389395 11382764 19138410 20068231 18707149 17194753 23457577 26477567 14996911 17016520 18669648
EGFR CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 17145710 22558232 18950621 23481205 25402006 12040186 24797263 9535896 17389395 20068231 19568798 27316454 14585353 17496910 24189400 15657067 24658140 31980649 26067913 15951569 14996911 17016520
ERBB2 CTNND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17496910 22558232 12040186 19568798 14585353
CXCR2 MAPK14 â—¼   UP_REGULATES ✅ + 8.0 1.0 ACSN 17254968 17533374 18555777 18633355 18980965 21328342 23869868 24954210
CXCR4 RHOA â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
CXCR4 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11668182
CYBB RAC2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11145705 1660188 18347018 11090627 10455184
DAB2 TGFBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 11387212
DAB2 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 20460648 21498506 21304492 19561074 22491013 15518237 19581931 17318175
DAPK3 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11226254 24712327 23345589
DDX17 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19995069 21182205 12738788 20348541 19718048 20663877 25604459
RHOA DIAPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22820501 12773565 18218625 16109481 15864301
EGFR SHC1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
MAPK14 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15187187 18039929 19138820 7535770 12738796 17139251 16932740 23397142 16785992 11274345
PRKCA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 11447289 8321321 11313945 25402006 12040186 20888375 15302935 6321473 1860884 12878187 6090944 19568798 14585353 17496910 21386996 24658140 2984676 11940581 31980649 15212693 85012702 19615955 2987962 12845332 3379075 7805884 10816576 15567848 16488589
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
PRKCE EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11447289 21749319 8321321 11313945 12359306 25402006 12040186 23830194 6321473 1860884 27016036 6090944 19568798 14585353 17496910 21386996 17942932 20692258 24658140 1556153 2984676 18042729 11940581 11185568 19615955 2987962 23205726 12845332 10816576 3379075 15567848 16488589 16793002
MAPK3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 1651322 17081983 3138233 15901825 16785992 1939237 91332050 27531070 17570479 2543683 2115882 34086370 17192257 1651323 15302935
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 78.0 1.0 Omnipath 9544989 8808684 10595738 23956138 9388490 11350724 16273093 7542991 7681824 7518560 9710588 23799367 16713569 25402006 11370743 24797263 9742218 20935677 8887653 8034616 23331499 8662998 7542744 10049786 28065597 9130710 10635327 24189400 7506413 18271526 15657067 24658140 8810340 12577067 11196191 10766863 23178716 31980649 35384245 11408594 19531499 9756944 26551075 1623525 15951569 16729043 17956904
EGFR MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12556561 15531749
EGFR PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16713569 16919435 25402006 10806474 29435030 20473329 7657702 19339212 17496910 15657067 24658140 19625610 7529872 20802513 31980649 10545505 24043698 15951569
EGFR EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 17389395 10953014 24269888 19534553 25260758 19583965 19690332 15951569 9049247 17016520
EGFR EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 1382070 31980649 24658140 12560083 9230083 15212693 10377409 15647376
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
MYC ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20920219 21627565 7906953 23421821 20716114
PRKCA ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 18799465 9855018 12040186 19568798 15567848 14585353
PRKACA ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18799465 9855018
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
ERBB2 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17496910 19617202 25241761 10545505 7657702 27638858 19339212 27939360 15743500 20201928 12753909 16919435 16713569 7529872 12600989 11807823
ERBB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16769082 19617202 11940572 12753909 21075308 7542762
ERBB2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 28065597 23331499 9756944 16273093 8026468 9710588 10085134 24658140 9590694 16713569 16729043 16843263
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MAPK14 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23216744 22431515 12138194 15879307
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
SRC EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16438931 22397367 14504278 25231728 21818323 24339867 15623525 18701134 22262457 24385580 18078820 28306714 15647376
PRKCA EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 14504278 15531580 10970850 11387207 21899702 15843435 9516463 15647376
FN1 SHC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19342448 21844907 10714768 8598224
FN1 PTK2 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
MYC FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14519204 11896591 8376401 10421838
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
MAPK3 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24089523
HNRNPA1 NCBP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10982855 9858549 1906035 9271388
MYC HNRNPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12747840 20010808 12695333
SRC HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7516469 17178840 24642125 12052863 7592945 16854432 16713569 21184736
MAPK3 HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11259409 16564677 11231586
HNRNPK KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21988832 22365833 31413325 16713569 12370808
SRC HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17855507
ILK TGFBR2 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11696562 15905178 24527345 25100717 25268583 27111285
PRKCA ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22521536 17570479 17420447
ILK PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 15826939 11931630 11384979 12030846 18669648 18767875 12220642 18077418 12563012 25168281 12919947 10601309 24356468 12600888 18212344
MEN1 IQGAP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
PRKCA IQGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 27815503 21349850 25618329 15695813 25733387 28739799 15355962 31474712
PRKCE IQGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 21349850 20495773 15695813 19295129 15355962
IQGAP1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11319218 8226933 1330321 16135787 17563371 7992057 8248196
IQGAP1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7731720 14970219 18567582 16135787 17563371
IQGAP1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15655247 11319218 8226933 1330321 1497021909368021 16135787 17563371 7992057 8248196
IQGAP1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 31980649 28007913 8798539 19079338 9199170 8670801 8702968 15695813 15217908 8756646 18809683
MAPK1 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18691976 12478298 19664995 20068231
SRC KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9038356 10467411 8766817 22745667 7537265 7516469 11960376 10635328 1374686 18606683 16169070 16713569 1545818 15190072
MAPK3 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17496910 18039929 19541618 21965663 20974802 19565474 15547943 12063245 12738796 11226259
MAPK1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17496910 18039929 19541618 21965663 20974802 19565474 15547943 12063245 12738796 11226259
MAPK14 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15187187 18039929 12738796 11274345 12697810
RAC1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
SHC1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10996427 23584453
MAPK13 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK14 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15187187 21675959 18039929 12738796 11157753 22521293 17255949 11238443 11274345 12697810
MAPK1 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21071439 19339977 19864431 21325048 22493283
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 PPP1R9B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21704645 15980451 15728359
MAPK13 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK14 PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 10601328 9374491 17099248 19112161 21451146 11481440
MAPK14 PPARGC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17570479 11741533
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15649893 20516082 16648474 15121840 12944472 10788511 11030334 10747897 17255949 11274345 12697810
PRKCA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
MAPK3 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 8798443 8960373
MAPK3 RPTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21757713 21071439 19339977 19864431
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
RPTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MYC SRSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12747840 22545246 23935626 18414489
NCBP2 WTAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
RAC1 NCKAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9148763 9417078 12181570
PRKACA NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10788511 10611249 15121840 11030334
SFPQ NONO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17452459 21988832 17145710 17507659 12403470 11259580 30021884 10858305 18042045 20421735 25959826
PRKCA NPHS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21321125
RPTOR PPARGC1A â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
RPTOR PPARGC1A â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
RPTOR PPARGC1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
RHOA PPP1CB â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PPP1R9B PPP1CC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10194355 24366813 26186194 28330616 23080069 10391935 26496610 25785436
PPP1R12A RHOA â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PPP1R12B RHOA â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PRKACA PPP1R9B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12417592 16300646 18669648 20068231
PRKAR1A PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17145710 15655353 17353931 26687711 11834733 24855271 32296183 24700472 9405392 25477193
PRKACA SPTBN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9798950 20166139 20068231 18669648 17088250
PRKACA PRKAR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27107012 15187164 32296183 17148597 21795691 33608270 25477193
PRKACA SRSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22393468
PRKACA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12654918 21572420 20591975 8599934 16109481 34088899 11162591 15890975
PRKACA RAP1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 8463283 9867809
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
PRKCA RAC1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10679481 10871288 16492141 18851840 20027184 21474067
PRKCA SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12052829 19651622 18669648 17924679
PRKCA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16628218 20027184 11284700 18851840 21474067
PRKCA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 17496910 11940581 21386996 10527887 2996780 11447289 19615955 16488589 6321473 8321321 12845332 11313945 2136766 17570479 12040186 19568798 15567848 14585353
PRKCE SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 11834516 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
SRC PTK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11476890 12531888 16919435 17496910 17517963 20027185 25572304 26552706 27216177 8892616
SRC PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 216.0 1.0 Omnipath 27351421 23242524 16254240 12370821 21940449 26142360 17525734 10593973 14604860 17389395 19171305 22402981 19339212 22353809 9748249 8941336 17570479 12464388 25226367 15611085 15817476 25241761 26393679 27978555 26833789 11927607 17828307 25913180 26866924 15247219 10085298 12387730 19055942 9507031 21454698 10973994 32814053 21057587 27931517 27438371 18793427 19695571 15735019 18560762 10592173 25319025 24389213 21852560 26689988 14984767 7505391 19568240 20103658 20822514 25868388 23275294 28423510 23764511 19625610 15561106 17192257 19138410 19369195 17088251 12753909 28701735 29190494 17016520 15598735 18814847 11821402 11418135 15728464 16291744 25067788 11602246 16713569 22287273 9032297 7997267 12960434 11369622 20616959 26079101 19534553 10931187 22710722 20068231 25866790 21347260 9822703 28202937 16153436 11980671 21855630 19826415 18464795 7529876 20621036 9330873 21473875 9425168 28956212 12615911 15951569 25814554 12876384 17438336 15212693 16966330 20705914 20847951 23729178 20407018 12558988 25127991 25918719 12590707 16360410 8054685 18814027 11696015 22800863 17117420 12495636 11278488 9864370 21776383 18083107 22814579 22194915 20515733 11119718 9148935 10428489 15743500 20655298 23065768 28213315 26923073 24015220 17289681 12110680 22006118 24164353 23109003 18935208 10753828 18233957 8816475 25118939 19664994 25530216 16760434 9330875 21266176 21034468
RHOA PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10208419 12087088 16153436 15657578
PTK2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 22163037 26816343 29036929 34252134
PTK2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11980671 10592173 16713569 10725339 10749687 9566877
SHC1 RAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17540168 11278486 11804587 12670394
RAC1 RPTOR â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10702316 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18000759 18372248 18492954 19022819 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19864431 20138985 20547845 20805416 21157483 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
RAC1 RPTOR â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10702316 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18000759 18372248 18492954 19022819 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19864431 20138985 20547845 20805416 21157483 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
RAC1 RPTOR â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 10702316 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18000759 18372248 18492954 19022819 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19864431 20138985 20547845 20805416 21157483 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
RAC1 RPTOR â—¼   DOWN_REGULATES ✅ - 40.0 1.0 ACSN 10702316 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16713974 17404308 17604271 17680028 18000759 18372248 18492954 19022819 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19864431 20138985 20547845 20805416 21157483 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
SRC RAP1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
SMURF1 RHOA â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 14657501 14722617 14744429 15265520 15761148 16472676 21572392 22949611
SMURF1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15761148 21572392 16472676 16622418 28658604 15710384 14744429 14657501 22949611
SRC SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 19901323 9388490 8939605 9096689 10971656 16497976 15592455 9121430 10891441 17389395 11687594 10329689 10482988 20068231 17570479 16189514 9685404 23109003 7516469 9927207 18840094 15688026 15212693 1409579 14963047 9710204 26551075 17016520 11075717
TGFBR2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12767520 22710166 19010789 16474430 19920116 22943793 17934056 20519943 12809600 21900405 11133108 14557817 15548370 17673906
SMURF1 TGFBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11278251 15221015 22298955 15761148 21572392 27048878 22949611
SRC SPTAN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12446661 11971983
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368