Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MTA1 HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23791785 16511565
H3C2 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
EED H3C2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
SMC3 AKAP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AKAP9 GOLGA2 â—¼   COLOCALIZATION 2.0 0.8 intact 7234073 19242490
MYB AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12096342 18945670
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
AR MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14619959 20610535
CHEK2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
MDM2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19816404 21986495
ATM SMC1A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 11877377 5215162
ATM HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
ATM PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12147700
BECN1 USP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21962518 22216260
CHEK2 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32187724
SYCP3 BRCA2 â—¼   COLOCALIZATION 2.0 0.8 intact 22116401 8303438
CDCA5 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CDCA5 SMC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17349791
HERC2 CHEK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
HERC2 CHEK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
CHEK2 MDM2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15862297 5217705
TCF7L2 COPS5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
NFKB1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19027835
YY1 CTCF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9756895
NFKB1 CTCF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21912613
DOT1L CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
MECP2 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
TNF EED â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080539 0908486107
ESCO1 KDM1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20331966
ESCO1 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20331966
ESCO1 SMC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18614053
ETV3 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18025162
SMC3 EVI2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMC3 FAM76A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MSANTD3 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 NSMCE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMC3 FRZB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SUPT5H GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GOLGA2 TRIM29 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
GOLGA2 SUPT5H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
SMC3 GPATCH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMARCA5 H2AFX â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19092802 19234442
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
PRKCA HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15367659
HNF4A TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20621834 16771709
HNF4A TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951069
IRF2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9625761 18802049
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
PLK1 MAGED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MBD2 MECP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11865062 20886097
MECOM YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1119229109 22308434
MSANTD3 SMC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMC3 MXD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9528857
SMC3 MXD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9528857
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
MYC TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
MYC TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15466196 12080469
SMC3 MYH11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NSMCE2 TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19308705
RAE1 NUMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17172455 0609582104
PLK1 SMC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11970886
PRKACA RPL37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPF6 PRPF31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PRPF31 SMU1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SMC3 PRX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAD21 SSU72 â—¼   COLOCALIZATION 2.0 0.8 intact 8080148 20818333
SMC1A RAE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18832153 0807660105
SMC3 RALA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TGFBR2 RPL37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RPL37A TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SF3B1 SMU1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SMC3 TBC1D25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMC3 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMC3 TMEM232 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TGFBR2 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SF3B1 SF3B3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SMC3 STAG3 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
DOT1L HIST1H2BJ â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
HDAC1 SMARCA5 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
SNRNP200 SRRM1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
H2AFX HIST1H2BJ â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ATM CHEK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 10973490
EP300 H31 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11691934 14752096 20587414 21875947 23587423 19801601 16717280 23415232 11689448 12498683 11830591 11884585 14585496 30902546 15611041 16287840 15308690 24722339 28465257 15834423 11983172 8945521 19270680 30428346 29033323 28844863 16415179 10545121 23870121 16109717 15136563 23934153 27585400 15951563 20368990 30110629 18838386 12237408 27208796
H31 HDAC2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11850410 12626569 24722339
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22013068 12960163 14662860 12471036 23811396 11739381 20065107
POLR2A SNRNP200 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CDCA5 PDS5B â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
EFTUD2 SNRNP200 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SF3B1 SRRM1 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
SF3B3 SRRM1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
SF3B3 SMU1 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
HIST1H2BJ SMARCA5 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
SOX2 MBD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24048479 21532573
MBD3 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24048479 30415952
SOX2 MTA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23667531 21532573
CDCA5 WAPL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31010829 26496610
STAG3 SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11483963 31010829
CUL2 SF3B3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23951410 21145461
FEZ1 PLK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SMC3 IQGA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31010829 26496610
MYC IQGA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
BAZ1A H31 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 25533843
H31 EED â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 17210640
H31 SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 26527279
H31 SMC1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 26527279
H31 RAD21 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 26527279
MIPT3 SMC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17043677 31413325
MIPT3 SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17043677 31413325
MAD3 MXI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MAD3 NFKB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 7694229 8255759
MYC PRS7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
CAB45 SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
MECP2 BAZ1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDCA5 STAG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31010829 26496610
CEP63 NDC80 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 34079125
KDM1A CHD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21937684 19703393
SMC1A CTCF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33196849 18219272
CUL3 SF3B3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23951410 21145461
DDX39B SF3B3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MYC DDX47 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
DISC1 SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17043677 31413325
EP300 KLF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
EPHA1 STAG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EPHA1 HOOK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EPHA1 SMC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOXC1 NFIX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 35140242
MYC GNL3L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
SOX2 KDM1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30442713 28794006
MXI1 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 7565735 32140074
SF3B1 MYC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20936779 29467282
MYC SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC SMC1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC RBM15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 29467282
SMC2 RAD21 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22145905 17113138
SOX2 RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23667531 21532573
REC8 SMC3 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
SF3B3 SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31010829 26344197
SOX2 TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
PRPF6 SNRNP200 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EFTUD2 SF3B3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SMC2 SMC3 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
SF3B3 SMU1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
H31 MBD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 33961781 26527279
RBBP4 MTA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
H31 MTA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 33961781 34079125
KIFA3 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
RAD21 UBP13 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33334891
PRS7 RAD21 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PRS7 SMC1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PRS7 SMC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CAB45 NEK4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SMC3 CEP63 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
SMC2 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
RAD21 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
STAG2 PDS5B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31010829 29867216 15855230 17113138
REC8 SMC1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 12759374 24981860
SF3B3 SMC1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31010829 22939629 26344197
PRPF6 SMU1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
SMU1 SNRNP200 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
CSNK2A1 HDAC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HDAC1 SFPQ â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
STAG1 STAG2 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
TUBA1A TUBB â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ESCO2 SMC3 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
SMC3 MAD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9528857
SMC3 MXI1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9528857
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
HIST1H2BA HIST1H3A â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CHD3 HIST1H3A â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
EFTUD2 SRRM1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EFTUD2 SMU1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
MTA1 HDAC2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6613464 18451879
ATRX H31 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21421568 29568061 33961781 34079125
H31 CHD3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11850410 29020631 25533843 29568061 16728976 34079125
SMC3 MAD1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9528857
HNRNPU POLR2A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HIST1H2BA HIST1H2BJ â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CHD3 MBD3 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
MBD2 RBBP7 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
HDAC1 MECP2 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
SSU72 POLR2A â—¼   DEPHOSPHORYLATION ✅ + 0.85 0.85 Signor 15125841
KDM1A H31 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31152129 16079794 16223729 20389281 16956976 16140033 20228790 29568061
H31 HDAC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11850410 26496610 24722339 31874856 26527279
MYC CAB45 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21150319 26496610
SOX2 CHD3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23667531 28794006
HDAC9 HDAC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10655483 12590135 10487760 16611996
MYC PDS5A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29467282 17353931
SMC1A PLK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27173435 26344197
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST1H2BJ HIST1H3A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CDCA5 PDS5A â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
H2AFX HIST1H2BJ â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
HNRNPH1 SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
KDM1A MBD3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21937684 23455924 19703393
MTA1 CHD3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12431981 28977666 26344197 24981860 17922035 9885572
SMC3 KIFA3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9506951 16713569
HDGF H31 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29568061 21907836 25281560
UBP13 SMC1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 31010829 26496610 33334891
UBP13 SMC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 31010829 26496610 33334891
HERC2 DISC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17043677 31413325 90000000
RBBP7 EED â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 12435631 26496610 26186194 27705803 28514442
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
SOX2 FOXC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
MYC HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 17314511 30415952 20195357
MYC KDM1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 23455924 32296183 29467282
MYC SMC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
MYC PDS5B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 29467282 17353931
SMC3 PDS5A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17349791 26344197 31010829 19906707 15855230 21111234 17113138
STAG1 PDS5B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29867216 26344197 31010829 15855230 17113138
RAB9A RAE1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29568061 28514442 33961781
SMC1B RAD21 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26344197
SOX2 SMC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
CDCA5 RAD21 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDCA5 SMC3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDCA5 STAG2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ATRX HIST1H3A â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SMC1A WAPAL â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MTA2 MTA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21670149 34026424 24981860 26344197 12920132
KDM1A MTA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21670149 19703393 26028330
H31 RBBP7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25330109 29263092 20080577 19410544 29568061 26527279 16622419
HDAC2 MAD1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11101889 9150134
SMC3 CDCA5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17349791 26496610 15837422 31010829 26186194 28514442 21111234
MTA2 CHD3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10444591 19703393 28977666 26344197 24981860 22939629 11297506
MTA2 KDM1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21937684 21670149 19703393
RBBP7 MTA2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
MYC PLK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29467282 27773673 30415952 17314511 33494392
NFKB1 SFPQ â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14743216 22536447
STAG1 WAPAL â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CDCA5 SMC1A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
STAG2 WAPAL â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ATM H2AFX â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CSNK2A1 HDAC2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EED HDAC2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HDAC2 YY1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MTA1 MTA2 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
STAG1 WAPL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20360068 17112726 29867216 26496610 31010829 17113138
STAG2 WAPL â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 29263825
WAPL SMC1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20360068 17112726 26496610 23242214 31010829 17113138
WAPL PDS5B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20360068 17112726 26496610 31010829 17113138
WAPL SMC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17349791 20360068 17112726 26496610 31010829 21111234 17113138
WAPL STAG2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25173175 20360068 17112726 29867216 26496610 31010829 29263825 17113138
H31 RBBP4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11850410 27098840 33961781 29263092 19410545 16622419 20080577 19498464 26527279 29568061 14718166 16728976 31435636 19410544
AKAP9 DISC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29961565 17043677 31413325 90000000
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
ATM SMC1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11877377 11877376
MYC CDK4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22094256 28205554 21988832 28628118
MBD2 CHD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10444591 11297506 28977666 24981860
HDAC1 CHD3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28977666 22939629 26496610 9804427 23752268 20585571 11784859 17827154 28514442 27068747 9885572
EP300 PAX6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10506141 35140242
MECP2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14593184 12473678 16331260 14647463
SMC3 PDS5B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17349791 26344197 26496610 31010829 22293751 15855230 17113138
STAG2 SMC1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17112726 10931856 29867216 26344197 24981860 26496610 23242214 31010829 19629043 29263825 17113138
ATM CHEK2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RAD21 WAPAL â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CDK8 MED17 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HIST1H3A KDM1A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NDC80 SMC1A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
SMC3 WAPAL â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
AR MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PDS5A WAPAL â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MTA2 MBD3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10444591 25123934 12124384 19703393 24981860 26344197 22939629 12354758 11297506
MBD3 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 17827154 24048479 26344197 21258344 16428440 12354758 28514442 27068747 19041848 10444591 25123934 12124384 23752268
MBD3 MBD2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10947852 10444591 24981860 15456747 15701600 11297506
MBD3 HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25123934 24981860 20388487 26344197 21258344 22939629 12354758 23752268 17827154 26949739 19041848
MTA1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21670149 34026424 24981860 16511565 22939629 26496610 9885572 27098840 26344197 21258344 10840944 14722073 26028330 12920132 33264408 17922035 28514442 16189514 26949739 18451879 11146623 23752268 20585571 29997244
WAPL PDS5A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20360068 17112726 26496610 31010829 21111234 17113138
WAPL RAD21 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25173175 20360068 17112726 26496610 22145905 31010829 28514442 17113138
PLK1 WAPL â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
MIPT3 DISC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17043677 31413325 12812986 90000000
PRKACA H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11749379 9892015
AR SMC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22695118 23417242 16637073
AR KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 16079795 22052438
AR TCF7L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12799378 20610535
PLK1 BRCA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28985013 32286328 12815053 24835992 14647413 24448238
NFKB1 BRCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10961992
MYC BRCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PRKACA CAMKK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 32913128 10187789 15209507
PLK1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
NFKB1 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24296733 18425349
DISC1 CEP63 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17043677 31413325 12812986 90000000
HDAC2 CHD3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28977666 24981860 22939629 9804427 12493763 23752268 17827154 12198550 30737378 26949739 9885572
SIRT6 CHD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CHEK2 TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 26799419 19375317
COPS5 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18926707 17879958
MAPK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19941816
CTCF RAD21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19369356 19826084
CTNNB1 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12944908 25241761
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
MYC DDX11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
MAPK1 ETV3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22028470
MBD2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10444591 33961781 10471499 12183469 12665568 27173435 24981860 21258344 17634443 26496610 11102443 23752268 28514442 11297506 27593931
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
KDM1A HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21937684 34031383 21670149 19703393 24981860 16079794 26344197 21258344 20164337 9804427 32882276 12493763 11102443 12032298 23752268 28667074 26949739 34050636
MTA2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10444591 20714342 19703393 18451879 12920132 26344197 21258344 31980649 24981860 22939629 12493763 11102443 19686092 23752268 11297506 30737378 26949739
HDAC2 SMARCA5 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
MYC IRF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
NFKB1 MEN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11526476 16713569 16651450
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MXD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8649388 10508165 8224841
SMC3 MXD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9528857
SMC3 MXI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9528857
MYC MXI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7565735 17093053
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
MYC SMARCAD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC THRAP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 12808131
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
PLK1 PDS5A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
PLK1 PDS5B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
RNF126 PLK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STAG1 RAD21 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17962804 6178082
STAG1 SMC1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17112726 10931856 29867216 26344197 26496610 31010829 11076961 31807710 17113138
STAG1 SMC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17349791 17112726 10931856 29867216 26344197 26496610 31010829 17962804 11076961 22885700 15855230 17113138
STAG2 STAG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29867216 24981860 31010829 17962804 11076961 30021884
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
SMC1A SMC2 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
EED HDAC1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
HDAC1 HDAC9 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
MBD3 RBBP7 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PDS5B STAG1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HIST1H3A RBBP4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PDS5A STAG2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MBD3 RBBP4 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CHD3 MTA1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CHD3 HDAC2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CHD3 MTA2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
SMC1A SMC3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
EED RBBP7 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
EP300 HIST1H3A â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CHD3 HDAC1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
AIRE HIST1H3A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CHD3 RBBP7 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MBD3 MTA1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
MBD2 MTA2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
MTA2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6613464 18451879
CHD3 RBBP4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RAD21 SMC1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
NIPBL STAG1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
BRCA2 PLK1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
MBD3 MTA2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
KIFA3 APC â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 11912492 16713569
RBBP4 SMARCA5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
STAG2 SMC3 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17962804 6178082
SMC1B STAG1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
HDAC2 MTA1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
MTA1 RBBP7 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
SMC1B STAG2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
HDAC1 MTA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
PDS5A SMC1A â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
PDS5B SMC1A â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
STAG2 RAD21 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17962804 6178082
SF3B3 SF3B1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12234937 11406595 28541300 10490618 26344197 24981860 22939629 21981285
CDK8 POLR2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
H2AFX HIST1H3A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PDS5B RAD21 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PDS5A RAD21 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
SMC1A STAG2 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
NIPBL RAD21 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
NIPBL SMC1A â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
HDAC2 MBD2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
MTA2 RBBP4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
HDAC2 MBD3 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
TCF7L2 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 11713475 5214798
RBBP4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 34518534 11302704 11102443 27705803 17827154 10734134 10220385 9885572 10471499 26344197 21258344 12091390 9150133 16713569 11602581 12920132 20127688 9790534 17643391 11470869 19686092 12943729 9150135 28514442 16189514 27068747 10444591 19703393 11171972 15451426 23752268 20585571 9520398 11118440 31435636
RBBP7 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 17255935 22939629 26496610 11102443 27705803 9885572 10471499 26344197 21258344 12920132 9790534 19686092 9150135 28514442 25885317 10444591 19703393 15451426 26186194 23752268
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
SMC3 SMC1A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 22939629 26496610 31807710 30021884 21880767 17112726 10931856 26344197 11590136 12759374 17349791 9789013 23242214 11877376 18832153 27173435 31010829 11076961 22885700 21111234 17113138
EED RBBP4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PDS5A SMC3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PDS5B SMC3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
BAZ1A SMARCA5 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SMC3 STAG2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MBD2 RBBP4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MBD2 MTA1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
PRPF31 SF3B1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HDAC1 MBD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
PDS5B WAPAL â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
POLR2A SSU72 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PRPF31 SF3B3 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
HDAC2 MTA2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
SMC1B SMC3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
PRPF6 SF3B1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
EFTUD2 SF3B3 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EFTUD2 PRPF31 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EFTUD2 SF3B1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
NIPBL SMC3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PRPF6 SF3B3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SF3B3 SNRNP200 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMC1A STAG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HDAC1 MTA1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HDAC1 MBD2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MTA2 RBBP7 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MTA1 RBBP4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SF3B1 SNRNP200 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SMC3 STAG1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2A SUPT5H â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PRPF31 SNRNP200 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA1 PSMC2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC1A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 STAG2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SF3B1 SF3B3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CTNNB1 TCF7L2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
EFTUD2 PRPF6 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
EFTUD2 SNRNP200 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PRPF31 PRPF6 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PRPF6 SNRNP200 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RAD21 STAG1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
MTA1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
ESCO1 WAPL â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
ESCO2 WAPL â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
WAPL RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 17112726
KDM1A H3C2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
SIRT6 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18337721 16439206 19408108
KDM1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16223729 20210320 18343668 20228790 15620353
MYC APC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22911891 12695333
PRKACA APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11050185 11166179 15649893 11689703
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
NFKB1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14576180 15517885 20159994 12165860 16619263
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
MAPK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18511414 9725910 10318905
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
KDM1A AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17277772 16079795
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
MDM2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17974989 26411689 27835608 26973243 15640443 12145204
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
H2AFX ATM â—¼   PHYSICAL_INTERACTION 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H2AFX ATM â—¼   SHARES_COMPLEX 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
H2AFX ATM â—¼   ENZYMATIC_REACTION ✅ 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
ATM MDM2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM SMC3 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
H2AFX ATM â—¼   REGULATES ✅ 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
PAXIP1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15456759 19414588 17690115
ATM MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 66.0 1.0 Omnipath 14654783 12383858 17936559 20651945 17303408 19816404 10611322 23150762 23277204 23386996 26416444 27258263 23002429 11331603 15865937 21556066 16163361 23708100 17570479 20514355 22264782 27177180 18265945 28690977 23847781 22264786 15140942 15964794 19788416 22624716 25201202 27462439 12607003 28050229 32350255 22649771 27956626 15459660 22976441 25247188 28904407 11877377 21859827 24534650 23405218 29290977 27568562
ATM TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16223874 17525332 15314656
ATM SMC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17303408 14657349 19690332 29988990 26673124 15302935 16163361 20068231 18452278 18077418 17570479 18669648 23847781 15964794 16906133 12607003 9789013 17525332 15459660 11877376 11877377
ATM SMC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 22369641 18442975 15964794 11877377 17303408 16163361 23847781 17570479 12607003 20501661 19906707 17525332 15459660
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 176.0 1.0 Omnipath 26683224 17303408 28852018 10713094 20080130 27545311 9488723 15342622 23941746 26485758 28937603 15279786 24882580 10744722 15125777 25746763 18583988 28051860 17570479 16531125 21329876 23892398 19607708 16940182 26643553 20396397 28259974 25361978 17660363 15459660 19375317 25247188 16311512 23118481 20498628 22030216 25613496 22420423 9407949 17918214 12493754 20859824 26158765 15700044 27558808 11901158 27602502 20637859 16163361 20599567 23638118 16481012 12242661 23847781 12024051 15140942 11728459 12454775 16936775 25450480 28950914 26295265 20160490 22319212 24349411 18006705 20723763 18678890 12805407 20860841 23386996 24050180 11668173 27271602 29304495 12447382 24798733 9889122 23347679 18794134 21147465 21421565 26516160 17715138 21376743 19440053 12773400 10973490 17174984 26442630 15694385 11877377 29022904 18809224 11850621 18787700 12718885 19481982 22743550 20372057 15212693 16085488 19101576 29555944 25954303 24473398 18087292 16794575 24492479 24244353 19793801 25404613 21102523 29156743 23253087 16997395 7575488 25808488 20647331 18584027 21851590 21315088 23705030 15629715 29741650 21772273 11025670 18590585 26610585 15964794 29434792 20068082 23006513 19881958 19230643 12607003 24769180 25249630 15024084 19772495 25714019 18603484 25173936 23666059 19473886 27568553 22808196
NFKB1 BECN1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 19289499 21725609 23178297 23572150
BET1 GOLGA2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 9094723 9647643 24119662 10747087 23378591 16303754 19164740 9307973 25406594 17038314 8663406
BRCA2 SFPQ â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA2 H2AFX â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 H2AFX â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 SFPQ â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
PLK1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 32286328 12815053
MYC CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15208653 12835716 24951594 21384303 14519204 22395148 10688915 17728244 11983916 18414489
MYC CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21988832 11602341 17093053 22094256
H2AFX CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
PLK1 CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 12024051 24844881 18802408 19216791 10973490 18804494 12242661 20126263 16189514 11901158 12493754
CHEK2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15862297 10710310
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
CSNK2A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12700239 12432063
CSNK2A1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17287340 19413330 22113938 18669648
CSNK2A1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11711551 18452278
CSNK2A1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22184066 23226345
CSNK2A1 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 19007248 16565220 20166139 17081983 20230923 25609639 19413330 19415658 20388487 20068231 18452278 18669648 18691976 17287340 12176973 19651622 12082111 19691289 24526703 18510355 18212344
CSNK2A1 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11522824 7735324 11313925
CSNK2A2 HDAC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19651622 19415658 12082111 16565220 19007248 19691289 18669648 20166139 18691976 17081983 20230923 20068231 18452278 17570479 17287340 19413330 18510355 18212344
CSNK2A2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17570479 17287340 19413330 18669648
CSNK2A2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12700239 19141652 12432063
CSNK2A2 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11711551 18452278
EED CTCF â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17851529 17761849 25135475 17185360
CTCF RBBP7 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17851529 17761849 25135475 17185360
CTCF RBBP4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17851529 17761849 25135475 17185360
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
MEN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
TCF7L2 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24214913 14706452 19347947 24317174
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
FLT3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17496910 22558232 17851558 12040186 19568798 22126602 14585353
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
CTNNB1 TCF7L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17145710 9488439 11713475 12446687 17143293 27902311 16569639 22014570 16724116 11955446 16442529 26350900 19202075 17050667 20126258 22056988 16306047 17914096 19443654 18391971 21670201 22155184 10080941 17283121 16230076 22304967 16630820 15684397 11713476 12861022 19304756 20492721 19816403 18772112
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
PDS5A ESCO1 â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
ESCO1 PDS5B â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
ESCO2 PDS5B â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
PDS5A ESCO2 â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
FGFR3 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
PLK1 GOLGA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12839990 20937827 15678101 11447294
HDAC1 TCF7L2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10485845 11266540 10559189 20405012
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 TNF â—¼   DOWN_REGULATES ✅ - 15.0 1.0 ACSN 10754326 10952726 11875494 12907458 14660645 14668329 15465827 15644117 16878026 17404308 17485448 21234400 22796940 23390297 7594497
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
MECOM HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11552981 23858473 16713569 11568182
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC2 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9016636 19139378 11486036 8917507
PRKACA HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22865920 20716686
PRKACA HDAC8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15242608 14701748 31633931 16809764
HERC2 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
MEN1 IQGAP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
PRKCA IQGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 27815503 21349850 25618329 15695813 25733387 28739799 15355962 31474712
IQGAP1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15655247 11319218 8226933 1330321 1497021909368021 16135787 17563371 7992057 8248196
MBD2 KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23000163 21452283 24163373 23928305 19738071
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK1 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12721286 15212693 14517250 14662762
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
PLK1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12383858 19833129 23948487 24265276 26754547
MEN1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11526476 16997566 16713569
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
TCF7L2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 12095419 19561604 19895682 15579438 26947016 16204248 12799378 12907606 17360646 9727977 21533051 20133699 15576399 19784072 24447505 12591729 20818421 18852287 11973610
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
TCF7L2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
PRKACA NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
NFKB1 YY1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17438126 21725609 23178297 23572150
NFKB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17513725 12058956 24337575 12657243 17704137 12471036 17707233 7624137 11259437 12686724 16433741 26114754 20237317 7876168 16707469 12117498 14976218 10485496 15465827 8622636 15812247 21138578 18990758 10748079 15013838 15749903 16916598 17646159 10754326 16040075 10837498 18285351 11675405 11739517 15743782 20066113 20617556 17085785 8530146 8805669 10919279 14960579 1740105 10963848 16055086 9742085 17292554 10553096 11312646 15543947 17442180 16285952 10079106 11297551 10551799 10201927 12907458 8679226 9281604 22782967 8219230 11749970 9916895 11094063 11490006 7895918 1618817 16483936 18057724 20722069 16569682 9452482 17407192 17082635
PRKACA NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19531803 12947093 17959673 15642694 15197457
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
PLK1 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15737063 25299182 18931676 18616427 11073952 19270156 19622404 19686080
PLK1 STAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19686080 19270156 18931676 19622404
PLK1 STAG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 18616427 19270156 19622404 19686080
PLK1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21253604 23226345 22248053
SSU72 POLR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15125841 20861839
RAB11A RPGRIP1L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 17574030 20399632 23253480 17646400 21273506
STAG2 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 28430577 12034751 11590136 25173175 22885700 29263825
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
PMS1 PMS1 â—¼   KO_DOWN_REGULATES ✅ - -7.89 7.88 PKG 28854368