Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
SETDB1 CBX8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDCA5 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CDCA5 SMC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17349791
SETDB1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUV39H1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PHF21A KDM1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15325272 16140033
MATR3 S100A4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HDAC2 PHF21A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
INCENP KIF22 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CDCA5 TPX2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DDB1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24249678 26679995 25189618 34026424
CDCA5 PDS5B â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CDCA5 WAPL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31010829 26496610
CDCA5 INCENP â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
ESCO2 SMC3 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
HDAC1 PHF21A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
VPRBP CUL4A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17609381 30166453 21145461 30590706 25532805 33355139 20870715 18606781 17630831 16949367 17079684 19295130 31973889
CUL4B HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25189618 34026424
CUL4B HDAC2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618 30737378
EHMT2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21258344 26028330
INCENP TPX2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CDCA5 PDS5A â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
HDAC1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16287849 26496610 23752268 28514442 26028330
EHMT2 KDM1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26751641 26028330
SMC3 PDS5A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17349791 26344197 31010829 19906707 15855230 21111234 17113138
CDCA5 SMC3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
SMC3 CDCA5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17349791 26496610 15837422 31010829 26186194 28514442 21111234
VPRBP CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21145461 22038470 26496610 33355139 16949367 28416635 31973889
WAPL PDS5B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20360068 17112726 26496610 31010829 17113138
WAPL SMC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17349791 20360068 17112726 26496610 31010829 21111234 17113138
SMC3 PDS5B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17349791 26344197 26496610 31010829 22293751 15855230 17113138
MCM5 MCM6 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
MCM2 MCM5 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
KDM1A PHF21A â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
HDAC1 PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14988403 11929879 16189514 16713569
WAPL PDS5A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20360068 17112726 26496610 31010829 21111234 17113138
ZNF143 ESCO2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20116366
RCOR1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 19497860 11602581 19703393 17938259 11171972 21258344 17956988 26496610 12192000 11102443 12032298 17939992 23752268 28514442 15897453 18806873
KDM1A HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21937684 34031383 21670149 19703393 24981860 16079794 26344197 21258344 20164337 9804427 32882276 12493763 11102443 12032298 23752268 28667074 26949739 34050636
RCOR1 HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 11171972 21258344 12192000 11102443 12032298 23752268 30737378 26949739
RCOR1 KDM1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21670149 24981860 32882276 11102443 21142040 26344197 21258344 24217620 20164337 16140033 18806873 34050636 20389281 28667074 27173435 19703393 16885027 16079794 11171972 26226427 16956976 17687328 21602794 12032298 22143567 21300290 34031383 34079125
CUL4A VPRBP â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
HDAC2 RCOR1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
MCM5 MCM7 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
PHF21A RCOR1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HDAC1 RCOR1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
MCM2 MCM7 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
MCM6 MCM7 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
HDAC2 KDM1A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
MCM2 MCM6 â—¼   CORRELATES + 0.96 0.96 CCLE 31978347
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PDS5A SMC3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PDS5B SMC3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CDC45 MCM7 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CDC45 MCM6 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CDC45 MCM2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DDB1 VPRBP â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
MCM5 MCM2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 14681455 23993743 25963833 26344197 11248027 22939629 12614612 15232106 22540012 24207054 16899510 16189514 17296731
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
KDM1A RCOR1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MCM2 MCM7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM5 MCM6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM6 MCM7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MCM5 MCM7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PCNA CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
ESCO2 WAPL â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
MCM6 CDC45 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 CDC45 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 CDC45 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC45 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 CDC45 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM6 CDC45 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 CDC45 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
CDC45 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
ESCO2 PDS5B â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
PDS5A ESCO2 â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
RCOR1 KDM1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 21300290 18806873 24217620 11102443 21258344 20389281 11171972 21142040 21670149 19703393 17537733 21602794 16885027 26226427 12032298 20164337 17218267 16140033 22143567 17687328 16956976 16079794
MCM6 MCM2 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 33961781 20211142 22939629 12207017 26496610 30100344 22540012 22863883 25963833 17296731 14681455 26344197 12614612 12694531 25416956 16189514 27173435 26167883 16899510 10567526
MCM7 MCM2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM2 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM6 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM6 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM6 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM7 MCM6 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488