Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PLK1 SGO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18331714
CCNB2 WAPL â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB1 WAPL â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CDK1 WAPL â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
H1-1 PDS5B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCNB1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB1 PDS5A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB1 PDS5B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB2 PDS5A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB2 PDS5B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CCNB2 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CDK1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CDCA5 SMC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17349791
CDK1 PDS5A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
CDK1 PDS5B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
PDS5B CYP4F3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESCO1 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20331966
ESCO1 SMC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18614053
NIPBL MAU2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0040242 16802858
PDS5B MTRF1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDS5B PPP1R36 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PLK1 SMC1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11970886
CDCA5 PDS5B â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CDCA5 WAPL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31010829 26496610
RHOB BASI â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
S15A1 PDS5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
S15A1 PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APJ PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APJ PDS5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GLPB PDS5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GLPB PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GLPB STAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MAS PDS5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MAS PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ACM4 PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
5HT2C PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
K1467 PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
K1467 CCNB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ANK1 PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD70 PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD70 PDS5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD70 STAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDCA5 STAG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31010829 26496610
MYC CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
LPAR4 PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC SMC1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
P2RX5 PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VIPR2 PDS5A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VIPR2 PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SCN3B PDS5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BASI PDS5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BASI PDS5B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SEP12 PDS5B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZNT4 PDS5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZNT4 PDS5B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LYPD3 PDS5B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LYPD3 PDS5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SCN2B PDS5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STAG2 PDS5B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31010829 29867216 15855230 17113138
SCN2B PDS5B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
STAG1 STAG2 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ESCO2 SMC3 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PCNA CCNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 8101826 33961781 7903056
PDS5B PALB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27924011 22293751
PDS5B RAD51 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27924011 22293751
MAU2 NIPBL â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
MYC PDS5A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29467282 17353931
SMC1A PLK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27173435 26344197
CDCA5 PDS5A â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
MYC PDS5B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 29467282 17353931
SMC3 PDS5A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17349791 26344197 31010829 19906707 15855230 21111234 17113138
STAG1 PDS5B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29867216 26344197 31010829 15855230 17113138
CDCA5 RAD21 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDCA5 SMC3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDCA5 STAG2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
SMC1A WAPAL â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SMC3 CDCA5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17349791 26496610 15837422 31010829 26186194 28514442 21111234
MYC PLK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29467282 27773673 30415952 17314511 33494392
STAG1 WAPAL â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CDCA5 SMC1A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
STAG2 WAPAL â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
RAD21 PCNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22145905 22939629 26344197
STAG1 WAPL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20360068 17112726 29867216 26496610 31010829 17113138
STAG2 WAPL â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 29263825
WAPL SMC1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20360068 17112726 26496610 23242214 31010829 17113138
WAPL PDS5B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20360068 17112726 26496610 31010829 17113138
WAPL SMC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17349791 20360068 17112726 26496610 31010829 21111234 17113138
WAPL STAG2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25173175 20360068 17112726 29867216 26496610 31010829 29263825 17113138
SMC3 PDS5B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17349791 26344197 26496610 31010829 22293751 15855230 17113138
STAG2 SMC1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17112726 10931856 29867216 26344197 24981860 26496610 23242214 31010829 19629043 29263825 17113138
RAD21 WAPAL â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
SMC3 WAPAL â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
PDS5A WAPAL â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
WAPL PDS5A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20360068 17112726 26496610 31010829 21111234 17113138
WAPL RAD21 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25173175 20360068 17112726 26496610 22145905 31010829 28514442 17113138
PLK1 WAPL â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
PALB2 BRCA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22331464 19369211 19268590 26990772 30410870 20871615 25016020 16793542 28319063 24835992 17420451 24141787 19553677 22193777 24485656 23585894 17200672 21466675 23038782 28240985 26833090 20332121 19584259 26649820 22293751 19609323 28765325 28398198
PLK1 BRCA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28985013 32286328 12815053 24835992 14647413 24448238
MYC BRCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PLK1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
PLK1 PDS5A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
PLK1 PDS5B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
STAG1 RAD21 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17962804 6178082
STAG1 SMC1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17112726 10931856 29867216 26344197 26496610 31010829 11076961 31807710 17113138
STAG1 SMC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17349791 17112726 10931856 29867216 26344197 26496610 31010829 17962804 11076961 22885700 15855230 17113138
STAG2 STAG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29867216 24981860 31010829 17962804 11076961 30021884
PALB2 RAD51 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
PLK1 CCNB1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 11242082
PDS5B STAG1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PDS5A STAG2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
SMC1A SMC3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
NIPBL STAG1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
BRCA2 PLK1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
STAG2 SMC3 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17962804 6178082
PDS5A SMC1A â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
PDS5B SMC1A â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
STAG2 RAD21 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17962804 6178082
PDS5B RAD21 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PDS5A RAD21 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
SMC1A STAG2 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
NIPBL RAD21 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
NIPBL SMC1A â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
SMC3 SMC1A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 22939629 26496610 31807710 30021884 21880767 17112726 10931856 26344197 11590136 12759374 17349791 9789013 23242214 11877376 18832153 27173435 31010829 11076961 22885700 21111234 17113138
CCNB2 CDK1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PDS5A SMC3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PDS5B SMC3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SMC3 STAG2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PDS5B WAPAL â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
RAD51 BRCA2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219969 17541404
BRCA2 PALB2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
NIPBL SMC3 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
SMC1A STAG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMC3 STAG1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RAD21 SMC1A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 STAG2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RAD21 STAG1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PCNA RAD51 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA BRCA2 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA BRCA2 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA RAD51 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
CDK1 SGO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24055156 29971233 26365192 29312936 23242214
ESCO1 WAPL â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
ESCO2 WAPL â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
WAPL RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 17112726
BRCA2 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PALB2 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17420451 16793542 26990772 19268590 22293751 17488615 19369211 23585894 24485656 20332121 24141787 26649820 19553677 17200672 26833090 23038782 17200668 15115758 19609323 30410870 19584259 22193777
PLK1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 32286328 12815053
BRCA2 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 87.0 1.0 Omnipath 17145710 21601571 15937124 17541404 11313963 16914443 26145171 21670257 18264088 19303847 25585578 12815053 16793542 21789034 25282148 17515904 9126738 20729859 15703751 21076401 15065660 22293751 19875419 12606939 22116401 12619154 23935068 15800615 33476590 15800651 15671039 11477095 16513631 9811893 10551859 20729832 9523196 14636569 17515903 12442171 9405383 26833090 21399666 19628690 9560268 10373512 14580352
MYC CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 11522645 11983916 19470724
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
PLK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20404109 16854412 26899266 19364923 25362646 20126263 12524548 26729093 11242082 12447691
CDK1 CDC45 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
CDK1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
CDK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17764786 17660363 15279786 15917306
PDS5A ESCO1 â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
ESCO1 PDS5B â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
ESCO2 PDS5B â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
PDS5A ESCO2 â—¼   ACETYLATION ✅ 6.0 1.0 Reactome 18411254 22101327 8291532 15958495 18614053 15821733
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
MYC RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 20940401
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
PALB2 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19423707 20871616 24141787
PLK1 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15737063 25299182 18931676 18616427 11073952 19270156 19622404 19686080
PLK1 STAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19686080 19270156 18931676 19622404
PLK1 STAG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 18616427 19270156 19622404 19686080
STAG2 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 28430577 12034751 11590136 25173175 22885700 29263825