Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAC1 PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11950936
HLA-C B2M â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211709 10429675
B2M RAB9A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
FBN1 MFAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1708799 10424889
ADAM9 PACSIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10531379 5211924
GNAS ADCY3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9228084 21406690
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
NEDD4L ARHGDIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ARHGDIA NGFR â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CD44 ARHGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12748184 16189514
ARHGEF11 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ARHGEF2 PAK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8397873 22653441
ARHGEF2 RHOB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16917499 18287519
ARL6IP5 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CANX MRPL16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
PDE6D CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDC42 NGEF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6493368 18256687
CDC42 RAB35 â—¼   COLOCALIZATION 2.0 0.8 intact 19289122 7012064
CDC42BPB MSN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10947843
PPIA CDK5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
EGFR RAB7A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18776048 0806158105
EGFR PTPN1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 9355745 6671413
JAK1 ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB2 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273093
FYN NGEF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15848799 11336673
GNA11 GNB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25675501 15889144
GNA11 PLCB4 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
IGF2R RAB9A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19490898 21421921
INSR PTPN1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 11506178 6671880
RHOB INSR â—¼   COLOCALIZATION 2.0 0.8 intact 14722096 6672086
PI4K2A ITCH â—¼   COLOCALIZATION 2.0 0.8 intact 23146885 8426259
NGEF RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6493368 18256687
PDE6D RAB18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PTPN1 RHOB â—¼   COLOCALIZATION 2.0 0.8 intact 14722096 6672086
PTPN1 RAP1B â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16005629 16115959
PTPRS RAB35 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAC1 RAB35 â—¼   COLOCALIZATION 2.0 0.8 intact 19289122 7012064
CAV2 EGFR â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ARHGDIA RAC1 â—¼   GTPASE_REACTION ✅ - 0.81 0.81 Signor 20696765
CHCHD3 IMMT â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
RHOB PLD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB ACSL4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB ADCY3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB ANO6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
DAB2 AP2B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22323290 34079125
HIP1 AP2B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15533940 34079125
RHOB ATP7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB BMS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB CD44 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
CD44 CLCN7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD97 JPH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAB7A CDC42 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31536960 31871319
CDC42 RAB1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
RHOB CEP89 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB CLCN7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB CNNM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB DDX18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB DDX31 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB DDX52 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB DDX56 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB DGKD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB DHCR7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB DOCK9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
GIPC1 DOCK9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 29467281
RHOB DSC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB ECT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB EFR3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB EHBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB EPHA7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB EPN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RAC1 FAT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
RHOB FRS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB HIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB HIP1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB IGSF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB JPH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
LMAN1 PHB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
RHOB LRP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB LRP6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB MPZL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
MYL6B RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 31871319
RHOB MYO1E â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB NSF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB OPA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB PAK4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
PAK4 RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 11756552
RHOB PALM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB PANX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB PEAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RAC1 PHB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 31980649
RHOB PKP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RAB1A RAB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
RHOB RAB23 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RAB2A RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
RHOB RAB7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB RELL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
CDH2 CTNNA1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIP1R PICALM â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
PTPRK ADAM9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RAB7A ARL8B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29360040 28325809 26344197
PTPRK EGFR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
GNAI2 MCU â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AP2B1 CLTC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
EGFR CD44 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23265944 12093135 16565089 15597342 11606076
GNAI2 GNB4 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
EGFR AP2B1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24189400 24797263 23956138 7534311
EHD2 AP2M1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15182197 16713569
CDK5 CABLES1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 20559324 7988653
AP2B1 AP2M1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PLD1 RALA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9207251 9688545
RAB5C CLCN7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
FYN PTPRF â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12496362 31413325
RAB7A PHB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31536960 26496610
EGFR PTPRF â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24189400 24797263 31980649
CABLES1 CDK5 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
IL6ST JAK1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
RAB7A RAB5B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10329441 26344197
PLD1 CDC42 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 10747870
FYN CD44 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9573028 16189514 16713569
DOCK9 CDC42 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 12172552
RAP1B CDC42 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 26344197
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
INSR PTPRK â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 19167335 26186194
RAB5C RAB1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
RAB7A RAB5C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
COBL PACSIN3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ARHGDIA CDC42 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EGFR AP2M1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31959764 24797263 31980649 24067654 23956138 25754235 20029029 24189400
PTPRJ EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19167335 19836242 9115287
RAB2A PHB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26496610 26344197 34079125
RAB7A RAB2A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26496610 26344197 34079125
EGFR PTPN1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CLTC HIP1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
RAB1A RAB8A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
RALA PLD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10611224 9207251
CANX B2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14681859 2450918 10064069
NFKB1 B2M â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12480693 2196446
FYN ARHGAP35 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18541700 23144976 11536198
ARHGAP35 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 1894621 10873807 32203420
GNA13 ARHGEF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11313914 15951850 22661716
ARHGEF11 RHOB â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
GNA13 ARHGEF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11799111 10026210
EGFR CAV2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 25402006 16799092 15273741
PAK4 CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31871319 26344197 17353931 31478661 11756552 20936779 9822598 29734338 32707033 16189514 26598620
PTPN1 CDH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9786960 11106648 12377785
PICALM CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16491119 10436022
PTPN1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   PHOSPHORYLATION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 6732094 9050838
EGFR PTPN1 â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 25796184
PTPRK EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16263724
EGFR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8524316 15284024
HIP1R HIP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11063258 11889126 33961781 28514442
RAP1B PDHB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDC42 PAK4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
HLA-B B2M â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8624811 5220994
CANX GANAB â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
KRIT1 RAP1B â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RAC1 ARHGDIA â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 8376617 22157745
RAB1A RAB7A â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
ARHGDIA RAC1 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
PDHB PDHX â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CCM2 KRIT1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PTPN1 INSR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 12634852 6671665
PTPN1 INSR â—¼   PHOSPHORYLATION ✅ 0.98 0.98 mint 6671880 11506178
PTPN1 INSR â—¼   PROXIMITY ✅ 0.98 0.98 mint 16926280 6671607
INSR PTPN1 â—¼   PROXIMITY ✅ 0.98 0.98 mint 12634852 6671665
PTPN1 INSR â—¼   DEPHOSPHORYLATION ✅ 0.98 0.98 mint 17481567 6732036
INSR PTPN1 â—¼   DEPHOSPHORYLATION ✅ 0.98 0.98 mint 6764581 15588987
B2M HLA-C â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
INSR PTPN1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL16 MRPS5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
B2M HLA-B â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ITGAV ITGB5 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGAV ITGB5 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
JAK1 ITGB5 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11306493 18633355 19833085 21840487 22470492 22595692 27216177 7512720 7521688
ITGB5 ITGA1 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
ITGB5 ITGA2 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
ADAM9 ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11162558
PAK4 ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 28007610 16189514 20507994 12356872
ADAM9 ITGAV â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15361064 11162558
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
ARHGDIA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 17245428 22157745 11368848 17353931 11513579 10346909 9490022 20696765 22393046 27173435 19961560 16189514 11513578 10673424 21900206
ARHGDIA CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 24276241 20936779 11368848 17353931 9490022 9113980 10816584 17045588 16189514 10676816 11149925 21900206
CDC42 ARHGDIG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
GNA13 ARHGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14607242 9641916 9641915 16189514 12681510
ARHGEF11 ERBB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
ARHGEF2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11595749 16189514 9857026
BMPR2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18756288 7791754 10712517
ECT2 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15642749 9490022 9113980 10816584 17045588 8836113
DOCK9 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9490022 9113980 10816584 17045588 8836113 12172552
CDC42 PAK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 10559936 11756552 29734338 15020669 16189514 11340065 15003621 20936779 10934474 11413130 17353931 22653441 11950587 26598620 11248548 9822598 18719708 10613909 10461188
FYN CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 24872417 19901323 9038181 10896159 18691976 20506281 29063113 20068231 16497976 19413330 14757045 12372285
CSNK1A1 RHOB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 27503856 18590726
CSNK1A1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 25301071 23331499 21887268 16890161 27821587 14731402 24794231 25735981 20229235 16341017
DAB2 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 20460648 21498506 21304492 19561074 22491013 15518237 19581931 17318175
RAC1 DOCK9 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15710388 15247287 12134158 17196961 17027967
NFKB1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14678988 18367518 12469217 17881446
PTPRJ EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19836242 9115287 19167335
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 25796184 31980649 8621392 12573287 18253097 11106648 11506178 24658140 7540771 9050838 9355745 15982634 25402006 10889023 7693694 8999839
ITGA5 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
FYN PTPRF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12496362 18854310
FYN ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16387660 17053785
JAK1 IFNGR1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNGR1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
JAK1 IFNGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12133952 8232552 8550631 8156998 7796299 7615558 8649432 19041276
JAK1 IL6ST â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8390097 9238703 16051226 11943154
IL6ST JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7896787 23331499 11468294 9388212 21220115 24710148 11742534 23663276 12487370
PTPN1 INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 10066179 12612081 11163213 17092689 11506178 15632081 8826975 8702689 16926280 14722096 8999839 23331499 8244979 15588987 11579209 16271887 10592173 1599438 9355745 11726652 12237455 10751417 17481567 21806020 19029027 1321126 12634852 11850117 10852715 15192089 10807907 16582879 17159996
PTPRF INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 23331499 7852302 10734133 15588985 11158333 10592173 1321126 8732688 19910497 8995282 1303753
PTPRJ INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1715686 10734133
NFKB1 PRKACB â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
NGF NGFR â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 9841888
NGF NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10764727 11729324 16893414 2172988 1372492 24224055 14985763 22227462 11114882 15258592 14699954 3037029 1714587 9775403
PRKACB NGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12682012 26119933
PDHX PDHB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632