SP1
|
COL1A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11114293
11013220
|
COL1A2
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9685391
30632962
|
SPP1
|
ITGB5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7592829
32196115
|
FGFR2
|
CCN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8400166
23142580
|
SP1
|
CCN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12888575
18481199
|
CCN2
|
FN1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16457822
5218313
|
CCN2
|
ITGA5
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16457822
5218313
|
THBS1
|
CCN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18550634
16878133
|
FYN
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7524477
6730342
|
ITGB3
|
CSK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10592173
11940607
|
ITGB1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0807543105
19168626
|
ITGB1
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19168626
|
FGG
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16581250
8649368
|
FGG
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11476890
16919435
|
ACVRL1
|
ITGA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8410211
22940691
|
SP1
|
ADAM17
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19772640
|
ADAM23
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10749942
|
ADAM23
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10749942
|
SP3
|
ANGPT2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16413606
17670746
|
PTK2
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5221628
9285683
|
VWF
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16581250
8649368
|
ITGB3
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16581250
8649368
|
FN1
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16581250
8649368
|
BCAR1
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16581250
8649368
|
FYN
|
CBL
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.8
|
0.8
|
mint
|
5217342
15556646
|
CBL
|
FYN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.8
|
0.8
|
mint
|
5217342
15556646
|
CBL
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9663390
15728256
|
CBL
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CIB1
|
ICAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SP1
|
COL18A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11093745
|
NFIC
|
COL18A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11093745
|
ETS1
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16564026
|
NFIC
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10082137
7504695
|
SP1
|
COL1A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19558215
|
COMP
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20033473
32196115
|
CRK
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
EGFR
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
SP3
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20435036
20407012
|
ENG
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8410211
22940691
|
ENG
|
ITGA5
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8410211
22940691
|
SP1
|
ETS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12706891
8247540
|
ETS1
|
ITGB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11556732
|
VTN
|
FBN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1708799
10424889
|
MMP9
|
FBN1
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
10229672
10386589
|
FN1
|
TNR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7499434
7527058
|
FN1
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11476890
16919435
|
ITGA5
|
FN1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16457822
5218313
|
FN1
|
ITGB1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21985969
8208414
|
PAX6
|
FN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21540023
|
SHC1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7516469
5220322
|
KDR
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219079
16966330
|
SP1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
PTPN2
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22080863
|
GPR182
|
ITGA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
VHL
|
HIF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218395
16511565
|
HIF1A
|
ITGB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19828020
23640055
|
HIF1A
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17848618
19016748
|
HIF1A
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19934262
15780936
|
HIF1A
|
RAC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19132225
20001745
|
HOXD3
|
ITGB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14610084
|
UBC
|
ICAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17174307
5219467
|
SP1
|
ILK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19176380
24361375
|
ITGB3
|
ILK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12372433
|
TGFBR1
|
ITGA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8410211
22940691
|
ITGA5
|
NRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19175293
1000025
|
POSTN
|
ITGA5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
20096135
22158103
|
NFIC
|
ITGA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18775869
|
PAX6
|
ITGA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10954416
|
POSTN
|
ITGB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
20096135
22158103
|
PAX6
|
ITGB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10954416
|
VTN
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7716514
32196115
|
PTP4A3
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19930715
16472776
|
SPP1
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7592829
32196115
|
NRP1
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218708
16763549
|
KDR
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15026417
9182576
|
VTN
|
KDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
31677479
32196115
|
SP1
|
LAMC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12034813
9403717
|
PAX6
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10885745
14673159
|
THBS1
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11606713
10900205
|
SP1
|
PAX6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11574690
|
RAC1
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18212043
18066058
|
VWF
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11476890
16919435
|
ZAP70
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15688026
5217506
|
SHC1
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10964917
8755247
|
SP1
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11133225
7499419
|
SP3
|
TIMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10764764
|
STAMBP
|
UBC
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
UBC
|
TGM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19183553
6824682
|
SP3
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
12414801
11517158
10825178
16734381
9329821
23825960
12200149
15247906
|
COL4A1
|
COL4A2
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
UBC
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
BCAR1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
COL6A1
|
COL6A2
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
ITGA5
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
HIF1A
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.81
|
STRING
|
36370105
|
CD81
|
RHOB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32900848
30024968
|
RHOB
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
RHOB
|
NISCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31871319
34079125
|
VCAM1
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
AUP1
|
SEL1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
ACVRL1
|
ENG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
CEBPB
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12665574
12847250
16651265
|
ZAP70
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
7760813
16189514
16713569
|
VCAM1
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
22623428
19738201
|
FN1
|
TGM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.84
|
STRING
|
36370105
|
CBL
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19380743
11149930
|
CD81
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
32900848
30024968
|
SHC1
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.86
|
STRING
|
36370105
|
ZAP70
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10419455
16189514
16339550
16713569
|
FN1
|
ITGA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
LAMC1
|
LAMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17517882
|
FN1
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CD81
|
CD9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
SP1
|
SP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CD9
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
FN1
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ITGB1
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
CRKL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CRK
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
BCAR1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
ITGB3
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
CBL
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
SHC1
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10037694
19380743
12048194
|
EGFR
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18271526
24658140
31980649
16729043
23397142
25754235
25402006
|
CBL
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
LAMB3
|
LAMC2
|
â—¼ CORRELATES
|
|
+
|
0.89
|
0.89
|
CCLE
|
31978347
|
ITGB3
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
HIF1A
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
BCAR1
|
PTK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
20332299
|
EGFR
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
16829981
|
ETS1
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16564026
24058639
11278621
|
SP1
|
COL5A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7646438
|
CCN2
|
FN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16457822
|
FGG
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16040750
14754902
10446041
|
VWF
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16040750
14754902
10446041
|
EGFR
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24797263
24658140
31980649
16729043
25402006
|
FN1
|
CSK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16040750
14754902
10446041
|
PTP4A3
|
ARF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
22595524
23691193
24376839
|
PTP4A3
|
ARF1
|
â—¼ SHARES_COMPLEX
|
|
|
3.0
|
0.9
|
ACSN
|
22595524
23691193
24376839
|
PTP4A3
|
ARF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
22595524
23691193
24376839
|
ARF1
|
ITGA5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
22595524
23691193
24376839
|
FGG
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16040750
14754902
10446041
|
FGG
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16581250
10777559
12640026
|
FGG
|
VTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16189514
2243140
11744726
|
SP1
|
ADAM17
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19772640
22705645
|
ADAM17
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14970227
|
HIF1A
|
ANGPT2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16338068
12958144
19491109
|
EGFR
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17145710
17570479
15951569
|
EGFR
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23158001
24797263
25872741
31182136
10635327
26055326
14505571
15210722
32714745
23774213
19155296
11370743
19836242
8665853
19947936
18271526
25140053
15668240
22394513
17486068
33323455
32377695
22203672
17182860
12604776
14627991
15383614
23153581
15735736
28541302
16849543
17242169
20562913
32904620
9121472
15677445
7782294
16923119
17995934
19531499
15465819
31959764
32114396
23457600
29629558
18316398
23799367
24714105
31120930
12061819
16713569
7657591
33617900
10086340
19225046
33762435
23175185
16729043
28791635
16246327
28198003
15962011
22266821
15117950
27059931
10428778
12734385
8662998
25005938
27903975
16969069
26177020
8798643
10799548
9756944
15159412
19578043
15657067
18255265
23418353
25754235
22976291
17545148
12803489
18319245
19713535
7592693
30544639
15107835
11994282
17971399
16105874
15282549
20940296
23897813
9130710
18273061
18508924
17880946
20124286
12593795
16914641
20877636
10092522
25521828
11408594
22591401
9890970
20308550
22833562
21772844
33627783
11239464
|
ZAP70
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10074432
29053960
10078535
11353765
11133830
9407100
8798643
10779765
9988730
22266821
16503409
|
SP1
|
CD9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8760289
|
ILK
|
CFL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18252715
|
CHAD
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9281592
|
COL4A1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8223488
|
ITGB3
|
COMP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16051604
20033473
15345499
|
ITGA5
|
COMP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16051604
20033473
15345499
|
ITGB1
|
COMP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16051604
20033473
15345499
|
VWF
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16581250
10777559
12640026
|
FN1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16581250
10777559
12640026
|
EGFR
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10595738
9480911
9642287
24658140
31980649
11956190
16729043
22973453
8875975
25402006
9617486
16273093
12198159
|
ITGB3
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16581250
10777559
12640026
|
CRK
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16581250
10777559
12640026
|
ZAP70
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
24658140
22973453
25402006
16273093
|
ETS1
|
VWF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9444957
|
HIF1A
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20631454
19285046
19950212
|
HOXD3
|
ITGA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14610084
|
SHC1
|
ILK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ITGA5
|
SPP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10673366
8910476
10593924
|
ITGA5
|
NISCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
ACSN
|
11121431
15157156
15229651
|
PTP4A3
|
ITGA5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
22595524
23691193
24376839
|
SP3
|
ITGA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18775869
|
LAMA5
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11964076
16413178
16581764
|
ITGB1
|
LAMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11964076
16413178
16581764
|
ITGB1
|
LAMB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11964076
16413178
16581764
|
ITGB1
|
LAMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11964076
16413178
16581764
|
LAMA2
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11278916
|
LAMC2
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10842354
|
LAMB1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10842354
|
ITGB1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19889638
10964917
|
VWF
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16040750
14754902
10446041
|
KDR
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24043698
22264731
29435030
|
L1CAM
|
NRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16377081
10520994
15121181
|
NFIC
|
VWF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11895773
20431063
|
SP3
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9329821
15247906
10825178
|
SP3
|
UBC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19733223
|
VWF
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16040750
14754902
10446041
|
ITGB3
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
LAMA5
|
LAMB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
KDR
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
BCAR1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
CBL
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
STAMBP
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.92
|
STRING
|
36370105
|
COL4A1
|
COL4A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
SHC1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9234717
9541596
15677445
8621719
16713569
8950973
10025673
10570290
8662998
19380743
9461587
9434624
|
CBL
|
EGFR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16914641
7033849
028274
|
LAMA5
|
LAMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
FYN
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9677430
8621719
12244174
7782294
10629042
119942
7642581
15556646
12231245
9311917
9535867
8626543
10799548
16713569
16503409
10092522
8900205
8995358
25814554
9890970
15190072
15208330
12941616
10829062
11239464
8662998
17094785
|
SHC1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10595738
24797263
24658140
7542744
21278788
9130710
28065597
10766863
10635327
8034616
24430869
7518560
12577067
19531499
31959764
8810340
9742218
11196191
23799367
23956138
9756944
16713569
11370743
8665853
18271526
15657067
11408594
20473329
22973453
16729043
20935677
20067773
7506413
16273093
25754235
8610109
24189400
26551075
9388490
8887653
31980649
7542991
9544989
9020193
25187647
25402006
30544639
10049786
8662998
|
LAMB1
|
LAMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
FN1
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
TLN1
|
VCL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
CBL
|
ZAP70
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
ITGA5
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
KDR
|
NRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CBL
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CBL
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
HIF1A
|
VHL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCN1
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9446626
|
CCN1
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9446626
|
SP1
|
COL1A2
|
â—¼ UP_REGULATES
|
✅
|
+
|
21.0
|
1.0
|
ACSN
|
10048576
10964912
11007770
11013220
11114293
15001984
15592504
16079281
16556862
16716598
16831886
17490644
17705132
18353785
18832382
19564415
20589835
21252118
22439866
23338822
8844971
|
SP3
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9242631
9278495
10771485
11511308
|
SP1
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
20429888
8182090
12760745
16319104
8524247
11348466
16564026
9242631
11114293
22049076
9278495
9143363
10771485
11278686
9882423
|
COL1A2
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1693626
|
SP1
|
ITGB5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
10964912
11007770
11013220
15001984
17705132
18353785
21252118
23338822
|
ITGB5
|
CRK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10837075
11146654
14697347
15031725
18353785
22035837
22470492
9295024
9763615
|
ITGB5
|
PTK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
22470492
24309651
26519775
9295024
9763615
|
ITGB5
|
BCAR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10837075
11146654
14697347
15031725
18353785
22035837
22470492
9295024
9763615
|
FN1
|
ITGB5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1694173
1532572
17015452
18480047
|
TLN1
|
ITGB5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19118207
22025551
12606711
32196115
|
ITGB5
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22824793
10592173
15673687
11927607
|
HIF1A
|
CCN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23530034
20450254
17034590
15315937
|
CSK
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
14754902
8755247
11940607
17218263
18434644
10964917
10446041
|
CSK
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10790433
11181701
12485116
15713798
19290918
8011291
8986721
|
CSK
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
1985196
8262983
11489946
16537894
9647655
25720756
18691976
10366594
19369195
1533589
1699196
7524477
16713569
15713745
14967142
|
CSK
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12767520
12048194
18829532
9819392
19380743
10037694
17673906
|
CSK
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18823558
21829547
9890993
27803182
21062671
7529872
21709741
|
CRK
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
SHC1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRKL
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
CRKL
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRKL
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
SHC1
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRK
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
CRKL
|
BCAR1
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRKL
|
CBL
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRKL
|
KDR
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
FYN
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10591186
10648627
11062502
12218089
12731048
15536084
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
|
CRK
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
CRKL
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRKL
|
BCAR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
BCAR1
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8978305
9498705
18835194
10592173
8810278
10753828
12345678
8943292
23770091
|
EGFR
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
31980649
23397142
18271526
24658140
25402006
16729043
|
CRKL
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8978305
9498705
18835194
10592173
8810278
10753828
12345678
8943292
23770091
|
TGFBR1
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
14580334
18333754
|
ADAM15
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10944520
9914169
|
ADAM15
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9914169
9516430
|
ADAM15
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9914169
9516430
|
ADAM17
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22413019
14970227
30455686
|
ETS1
|
ANGPT2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18720385
15003510
17287278
|
CRK
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
11146654
11353765
12094222
12432077
14697347
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
9808620
|
BCAR1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11353765
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
|
CRK
|
BCAR1
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
11146654
11353765
12094222
12432077
14697347
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
9808620
|
BCAR1
|
CBL
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11353765
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
|
FYN
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
17129785
9188452
9020138
10739664
31413325
16713569
11181827
9360983
17474147
|
PTK2
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
8649427
7479864
12135674
15673687
8810278
9038154
8670206
9285683
11604500
11119718
12480533
24939893
8621540
11577104
9360968
9148935
10592173
12119061
12972425
9360983
10092764
21855630
10753828
11839772
18233957
10545505
12615911
8662921
11514617
|
BCAR1
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
9920935
11369773
11278916
15673687
8662907
9581808
8631823
8070403
10747099
12065577
10329689
16267043
10592173
10208419
17038317
18835194
20627867
16413489
10753828
8943292
9860979
11839772
14657239
12799422
19380743
15492270
10085298
12615911
|
CRK
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11353765
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
|
CRK
|
CBL
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11353765
15169881
15308668
16000375
16076871
18835194
19454690
20189481
22464172
|
CBL
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11353765
15169881
18835194
20189481
|
FYN
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
97.0
|
1.0
|
Omnipath
|
9525940
7642581
8626543
7782294
15208330
16503409
16713569
10829062
10799548
10934191
8900205
8551236
8662998
8995358
19734451
12604776
9890970
10592173
17570479
10629042
17094785
10092522
11997497
12522270
15556646
12244174
8621719
9102067
22880054
9311917
11239464
19904769
11994282
12941616
9535867
25814554
12231245
15190072
|
CRK
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
8683103
16289966
8626543
8621483
9617486
16713569
9416834
8524328
10962563
8626404
9367879
8662998
12393469
11792427
15581361
9013636
15581362
9178909
9988765
18835194
8943292
20697350
9129019
19380743
25814554
9461587
|
CBL
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
11133830
10779765
10358158
16503409
8798643
20189481
22266821
23109003
18835194
10074432
10078535
15268851
15169881
26192618
9407100
9988730
11353765
|
CBL
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
188.0
|
1.0
|
Omnipath
|
34609770
16105874
18273061
22239438
24797263
20332299
17635922
23158001
17545148
8662998
12604776
9890970
23153581
17182860
25872741
12593795
23175185
10092522
15107835
22266821
22833562
24714105
17242169
25140053
20124286
19531499
9756944
10086340
22203672
19225046
16729043
15282549
20562913
22394513
20940296
23331499
7592693
19713535
10635327
19836242
15465819
15210722
25521828
23897813
10514377
12734385
18508924
11994282
20877636
33323455
22976291
23774213
23027125
15159412
18255265
16246327
28541302
16849543
23799367
16713569
10799548
8798643
19155296
9121472
17486068
21772844
16969069
15677445
15962011
23418353
12803489
32714745
14505571
27903975
19578043
26177020
11239464
18319245
11408594
10428778
12061819
17995934
17971399
27059931
26055326
15735736
23457600
7782294
22591401
29629558
11370743
7657591
21071413
28198003
18316398
19947936
9130710
18271526
15657067
31182136
16923119
17880946
32904620
15117950
14627991
15668240
15383614
|
ITGA5
|
CFL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
15866889
16919435
17522712
18037882
19161977
19339212
19454690
19487819
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
ITGB1
|
CFL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
15866889
16919435
17522712
18037882
19161977
19339212
19454690
19487819
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
COL18A1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12682293
|
COL18A1
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11158588
12682293
|
SP1
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
10091149
16575855
9666093
10775443
12138160
11348466
17698844
16564026
10082137
7504695
7590335
|
SP3
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9666093
10082137
17698844
|
COL1A1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7716514
10464311
7688313
|
COL1A1
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
1693626
16189514
|
SP1
|
COL2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18044710
11447232
12888570
18065760
16650379
12637574
|
SP3
|
COL2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18065760
11447232
12888570
|
COL2A1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9685391
7688313
|
SHC1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRK
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
SHC1
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRK
|
KDR
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10022831
11166270
11960372
12629515
13678960
15099563
15111329
15308668
15501236
15520864
15573129
16000375
16002046
16076871
16530705
16572188
17086423
17883421
18835194
19414323
19454690
21372296
22064427
22461508
22464172
23390297
24217602
24346288
25922287
26201938
8837607
9157999
9570538
9753319
|
EGFR
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
52.0
|
1.0
|
Omnipath
|
10595738
9480991
16273093
9617486
25402006
17399949
8662907
8875975
21602891
20068231
8194526
12198159
9642287
11956190
24658140
26656091
9480911
31980649
15212693
26473374
16729043
17016520
|
CRK
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
7561682
25814554
12370821
20068231
11602246
10085298
12615911
7509446
7529876
17016520
11314030
|
EGFR
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
SP1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
1282800
17616668
18575762
19538880
15665278
18202149
20435036
21705183
18007664
21464950
23821666
15533438
9819401
10830317
8393457
16087726
20407012
18391986
|
PTPN2
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15592458
15588985
9488479
10488121
11514572
11479308
|
TNC
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11470832
|
ICAM1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16799092
17145710
|
EGFR
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
78.0
|
1.0
|
Omnipath
|
9544989
8808684
10595738
23956138
9388490
11350724
16273093
7542991
7681824
7518560
9710588
23799367
16713569
25402006
11370743
24797263
9742218
20935677
8887653
8034616
23331499
8662998
7542744
10049786
28065597
9130710
10635327
24189400
7506413
18271526
15657067
24658140
8810340
12577067
11196191
10766863
23178716
31980649
35384245
11408594
19531499
9756944
26551075
1623525
15951569
16729043
17956904
|
EGFR
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16713569
16919435
25402006
10806474
29435030
20473329
7657702
19339212
17496910
15657067
24658140
19625610
7529872
20802513
31980649
10545505
24043698
15951569
|
TGFBR1
|
ENG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12015308
16785228
30761306
20042635
24319055
|
ETS1
|
TNC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
15001984
15111329
15181457
16391805
17615296
21041997
21081489
22608498
9157999
|
ETS1
|
ITGB3
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
10048576
15001984
15003528
15111329
15181457
16079281
16391805
16556862
16682805
17615296
17872466
18337545
19208835
19564415
20589835
21041997
21081489
21317430
22439866
22608498
23691193
24376839
7512751
7528107
8844971
9157999
9811054
|
ETS1
|
MMP9
|
â—¼ UP_REGULATES
|
✅
|
+
|
27.0
|
1.0
|
ACSN
|
10048576
15001984
15003528
15111329
15181457
16079281
16391805
16556862
16682805
17615296
17872466
18337545
19208835
19564415
20589835
21041997
21081489
21317430
22439866
22608498
23691193
24376839
7512751
7528107
8844971
9157999
9811054
|
ETS1
|
TNC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16245312
15001984
10618716
14734780
|
ETS1
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22270366
15949416
16722933
11556732
22206665
10949659
|
HIF1A
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
17615296
9157999
9278421
11708773
16716598
12080085
10403805
16887934
15181457
7539918
12490555
1823643
12829734
13130303
15451019
9746763
8943284
15111329
9159130
11566883
21041997
|
ETS1
|
MMP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10048576
16391805
17615296
15111329
19564415
9157999
16079281
21081489
21041997
15181457
|
ITGB1
|
FN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGA5
|
FN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
FN1
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19342448
21844907
10714768
8598224
|
ITGA5
|
FN1
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGB1
|
FN1
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGB1
|
FN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
FN1
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
FN1
|
PTK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
FN1
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
SP1
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15908479
16341057
9671487
1845987
8803927
2542772
7565693
15608673
9566920
1404598
2170405
10421838
|
TNC
|
FN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7499434
20708078
21349332
|
THBS1
|
FN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
19542224
11773026
18042364
18226512
|
FN1
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
11423542
1694173
6325925
11801679
18480047
16457822
10772816
9211865
1532572
25237190
26456826
19738201
23154389
22451694
17015452
20643357
|
FN1
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11423542
1694173
18480047
1532572
8663002
17015452
|
FN1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
9842903
22451694
17015452
18480047
19738201
7688313
1694173
6325925
25237190
26456826
10772816
7626807
21985969
6284125
1532572
11010812
8120056
|
ITGA5
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGB1
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
FYN
|
RELN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
17350651
23052211
23506116
16529723
|
KDR
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
SHC1
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
FYN
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
11369622
12558988
15494733
20151426
12590707
16293639
7505391
15728464
11278857
16713569
10753828
15494732
10085136
15494734
|
FYN
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
96.0
|
1.0
|
Omnipath
|
19901323
20230923
16497976
9121430
15592455
16713569
9446569
17389395
23331499
18578522
10921922
10482988
10764799
18452278
20068231
10592173
18669648
12522270
9685404
10896916
7516469
9927207
12237775
8702728
8610109
19651622
9741627
9710204
19664994
17016520
10816433
11075717
|
FYN
|
ZAP70
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7760813
16713569
16839418
|
VHL
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18931676
18985005
19622404
19686080
19809470
19847258
|
HIF1A
|
VHL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12205091
15930297
21887475
22150821
22396654
15962286
23159849
17482131
17140440
16883594
|
VHL
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
123.0
|
1.0
|
Omnipath
|
17145710
21332579
24857547
12682018
26496610
11292861
11024059
15060148
16278378
12586829
17353276
12004076
12205091
17339318
10823831
11226425
21602890
16862177
15611064
12351678
16140212
11865071
26037477
16611863
10973499
23401859
25361009
11331613
18305400
25438054
14691445
17047048
12538644
22932900
18985005
26735336
21358672
18323857
10878807
19147576
16511565
17973296
23413029
24316222
11986208
12808024
12464182
23318261
22369643
19940151
15721254
20724477
21335603
16391536
23387829
18694926
26743088
14556007
18264140
10353251
15082527
11358837
11292862
11566883
12050673
19123984
17558023
27281823
15805242
11641274
25500545
34174286
24899725
12606543
32535973
17132228
24015760
12086861
11504942
35589690
26215701
22351759
12925778
18222538
17986458
14600153
10944113
23580587
26611735
18426857
20049704
|
HOXD3
|
ITGB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17187229
11850808
14610084
|
ICAM1
|
TLN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10591186
11592085
12413632
12616499
14662834
15356110
1673988
19454690
19965656
20231889
2150484
23364881
23886063
24343663
24440149
25384214
7512027
9712030
9738502
|
ICAM1
|
TLN1
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10591186
11592085
12413632
12616499
14662834
15356110
1673988
19454690
19965656
20231889
2150484
23364881
23886063
24343663
24440149
25384214
7512027
9712030
9738502
|
ITGB1
|
ILK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
18339839
9736715
8538749
16189514
11402068
|
ITGB1
|
ITGA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
29.0
|
1.0
|
ACSN
|
10461188
10545505
10559936
10613909
11340065
11413130
11950587
12731048
15866889
16076871
16919435
17522712
18037882
19161977
19339212
19454690
19487819
20644254
20814939
22067905
22154077
22470492
24202395
7529872
7657702
9003039
9456329
9763606
9973479
|
ITGA5
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19342448
21844907
10714768
8598224
|
ITGA5
|
PTK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGA5
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGA5
|
PLA2G2A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
11.0
|
1.0
|
ACSN
|
18037882
19161977
19454690
19487819
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
SP1
|
ITGA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22227038
18775869
15825163
24130169
|
VTN
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11331280
23154389
|
TNC
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9314546
|
SPP1
|
ITGA5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7592829
16713569
|
ITGA5
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10545505
7657702
9003039
11927607
19339212
19487819
19161977
16919435
7529872
|
VTN
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
2412224
2420006
7685013
7542669
|
PTP4A3
|
ITGB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
16472776
19161977
19454690
19487819
19930715
22470492
23092334
23691193
24376839
27588115
28284838
9003039
9456329
9763606
9973479
|
PTP4A3
|
ITGB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
16472776
19161977
19454690
19487819
19930715
22470492
23092334
23691193
24376839
27588115
28284838
9003039
9456329
9763606
9973479
|
ITGB1
|
PTK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGB1
|
ZAP70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
12731048
18037882
19161977
19454690
19487819
20644254
20814939
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
ITGB1
|
PLA2G2A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
11.0
|
1.0
|
ACSN
|
18037882
19161977
19454690
19487819
22067905
22470492
24202395
9003039
9456329
9763606
9973479
|
TLN1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
19118207
12606711
7716514
3124107
10497223
19118212
21947080
11279249
|
THBS2
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15292271
|
RELN
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
10725376
10939329
|
TNC
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14715956
|
VCAM1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12097820
22623428
19738201
19057841
11751331
|
SPP1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10593924
7592829
|
THBS1
|
ITGB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15292271
|
ITGB1
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8649427
21909923
8878413
10545505
7657702
9003039
19339212
19487819
19161977
16189514
16919435
7529872
19889638
|
VTN
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
7525578
7559467
17968485
9251239
7685013
9443892
|
ITGB3
|
L1CAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
11553709
19161977
8636223
9003039
|
PTP4A3
|
ITGB3
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
10048576
16617148
16831886
17563753
17671186
18832382
20731704
21317430
22406545
23691193
24376839
7512751
7528107
|
TLN1
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
19118207
12606711
17218263
35044719
11932255
10497223
9065427
18156175
32196115
12535520
20739287
16546176
|
VTN
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16195248
11331280
|
THBS1
|
ITGB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
2478219
14963009
|
ITGB3
|
PTK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9169439
8649427
10545505
7657702
8636223
10022831
19339212
11927607
11940607
19161977
10592173
16919435
7529872
11553709
8755653
7512751
|
SHC1
|
KDR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
SHC1
|
KDR
|
â—¼ SHARES_COMPLEX
|
|
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
THBS1
|
KDR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
6.0
|
1.0
|
ACSN
|
10657674
11982756
14568985
14996710
22943793
8349738
|
SP1
|
KDR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
19888537
14684628
15111490
12560084
19469899
21980525
16678129
18006642
9079666
12067897
21430706
16574784
|
SP3
|
KDR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15111490
16678129
18006642
9668119
16574784
|
PTPN2
|
KDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19737086
18840653
|
NRP1
|
KDR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
17222790
11333271
16763549
11948691
19857463
26037503
|
KDR
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
10749680
9405464
11950700
|
KDR
|
NRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17145710
17222790
11333271
16763549
11948691
19857463
26037503
|
PTP4A3
|
MMP9
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
23691193
24376839
24686170
27328425
27510662
27572739
|
SP1
|
MMP9
|
â—¼ UP_REGULATES
|
✅
|
+
|
21.0
|
1.0
|
ACSN
|
10048576
10964912
11007770
11013220
11114293
15001984
15592504
16079281
16556862
16716598
16831886
17490644
17705132
18353785
18832382
19564415
20589835
21252118
22439866
23338822
8844971
|
SP1
|
MMP9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8226872
24755270
18028425
9514098
9520415
23799155
20529870
21840940
7860222
17049831
21963718
18357389
9150367
11060311
19616522
11830485
9748266
20638438
|
RAC1
|
NISCH
|
â—¼ UP_REGULATES
|
✅
|
+
|
11.0
|
1.0
|
ACSN
|
11121431
11274345
11544274
11756498
15157156
15229651
18000759
19151919
24459205
27331412
9655398
|
PTK2
|
TLN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9442086
7622520
15688067
|
PTK2
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20936779
22163037
26816343
29036929
34252134
|
PTK2
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11980671
10592173
16713569
10725339
10749687
9566877
|
PTP4A3
|
RAC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
16540666
17192274
17409395
18268019
20681446
22677902
22825514
23691193
24030100
24376839
25687758
27036022
27452906
|
PTP4A3
|
TIMP2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
10048576
16617148
16831886
17563753
17671186
18832382
20731704
21317430
22406545
23691193
24376839
7512751
7528107
|
PTPN2
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15588985
9488479
|
SHC1
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17540168
11278486
11804587
12670394
|
TGFBR1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
12767520
22710166
23331499
19010789
16474430
19920116
22943793
17934056
20519943
12809600
21900405
11133108
14557817
15548370
17673906
|
ZAP70
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
90.0
|
1.0
|
Omnipath
|
19901323
7961936
9388490
20230923
9096689
16497976
9121430
15592455
9446569
10891441
17389395
11687594
18578522
10921922
10482988
10764799
18452278
20068231
16189514
18669648
12522270
9685404
10896916
9927207
15688026
12237775
8702728
8610109
19651622
9741627
8761298
9710204
19664994
17016520
10816433
11075717
|
SP1
|
TNC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
10964912
11007770
11013220
15001984
17705132
18353785
21252118
23338822
|
SP3
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
21554857
12509426
9632663
10362515
19223508
15857802
20096088
16806531
15854045
15118068
9788252
12773549
16617124
11517158
12554796
9666093
15869407
12888570
11287330
15541732
8845379
16574784
8070411
|
SP1
|
TNXB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10631113
18588874
|
SP1
|
TIMP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15691353
16275157
10764764
|
SP1
|
TNC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16245312
15001984
10618716
|
SP1
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24240095
11126367
17689681
|
SP1
|
UBC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19733223
17409431
11872750
|