Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 SOS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 RIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 FYB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CD2AP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 PTPN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PRKCA ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10713049
ABL1 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17893873
SRC HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16844778 0604705103
HSP90AA1 RIPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
HSP90AA1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KAT6A ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK3 SOS1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK3 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
PRKCE MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16810323 16461926
PRKCB MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8903320 10327068
PRKCD PTPN22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0706233104 18056643
ITGB3 PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731544 12791772
PDGFB PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7691811 9739761
PTPN11 DOK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15546884 6673248
PTPN11 ANGPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521483 9764820
PTPN11 MET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18579758 6731904
GAB1 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
PTPN11 SRC â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
PTPN11 KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9405464 19706677
TP53 REV3L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
TP53 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 NDN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10713459 10347180
TP53 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10614633 9895308
XPO1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17268548 17891139
PIK3R3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32606738
SIK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19622832
TP53 ANLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1301998
TP53 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
ITGB2 ITGAL â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19161977 21270398
ITGB2 ITGAL â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 19161977 21270398
BATF3 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12087103 10878360
DOK1 ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19118207 12606711
SRC ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19910644 10592173
ITGB5 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19910644 10592173
HSPB1 KCTD13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ITGB3 ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214491 11546839
ITGAV TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PDGFRB CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10733900 6731185
SOS2 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK SPEN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK RIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK USP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CRK ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CRK ASAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
EPHB3 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9674711 16713569
BCR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8978305 21602891
PDGFRB GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14973141
ELK1 PDGFB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9690620
PDGFB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15845350 12753909
YWHAB ITGB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213955 11313964
ITGB1 PHLPP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DOK1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19118207 12606711
ATXN1 TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGFBR2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16360132
ITGA4 ITGB7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12626562 19454690
ITGA4 ITGB7 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 12626562 19454690
ITGA6 ITGB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19161977 22118458
ITGA6 ITGB4 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 19161977 22118458
AR NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 15135217
HSPA8 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BRAF MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16888650 5218924
MAP3K1 MAP2K4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6548305 9808624
MAP2K4 MAP3K1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7855889 7997270
MAP2K4 MAP3K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6548305 9808624
BRAF MAP3K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16810323 5218785
DOCK4 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
SRC RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 23027962
PIK3CB ANGPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521483 9632797
SOS1 ANGPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11191051 7478529
SOS2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RIN3 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAP4K1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC ASAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17094785 7033811
SRC FCGR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8756631 18083107
CBLB ASAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
CBLB ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
CBLB ERBB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLB PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLB PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLB PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CD3G PRKCQ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16978534 12473184
CBLC ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBLC MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC ERBB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
BRAF PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
PRKCA PRKCE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
PRKCA RPS6KA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
PRKCA SNX10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCA SEPTIN6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHLPP1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21986499
RPS6KA2 BRAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
PIK3CD PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9885561 10455108
ITGB4 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9428518 11733063
ERBB4 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 17496910
HSPA8 RIPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
AR IGHG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12734361
AR PIK3CB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23365759 20610535
AR RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20587519 11255259
ERBB4 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 17496910
TWIST2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIM2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ITGB4 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SPEN ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
C1orf94 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PRRC2B ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
WDR83 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAD54L2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 PIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
WDR83 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HSPB1 NDN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 TASOR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SOS1 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707404
GAB1 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8596638
GAB1 PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8596638
GAB1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11707404
IGHG1 PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGKC PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
CD3G PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR3A PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR2A PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
FCGR1A PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
IGHG4 PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
PIK3CB TEK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10521483 9632797
ERBB4 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 17496910
GFRA1 SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9764818 10995764
TEK SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11191051 7478529
GDNF SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9764818 10995764
NTF4 BDNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
NTF4 BDNF â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
RET GFRA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
RET GDNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
UTRN PTPN12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MET SEMA4D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18025083 12198496
CD3G PTPN22 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 22426112 16461343
IGKC IGHG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11183784 5213535
IGHG1 FCGR3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
TCOF1 ZNF462 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
IGHG4 FCGR3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1314888 2474607
MAP3K7 MAP2K6 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 21902831
FGFR1 CRK â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10464310 25241761
ITGA2 ITGB1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ITGA5 ITGB3 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
ABL1 EPS15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 19380743
ANLN AP2M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
DAB1 CRK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15062102 15316068
CRK ARAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 31980649
FGFR2 FGFR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SOCS1 PIM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29991678 11854514
BRAF HSPB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 31980649
SOS1 BCR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 8112292 7529874
ASAP3 ASAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ASAP1 CD2AP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 15632162
NTRK2 NTF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 8621424
ASAP3 ASAP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PIK3CG PIK3R5 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HSP90AA1 SRC â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
MAPK3 HSPB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 21575178 8774846
RHOA MYO9A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31871319 32203420
SOCS1 FLT3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10022833 29991678
CDK13 NEK3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MAPK3 RPS6KA2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
MAP3K7 RIPK2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NDN TP53 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CRK MAP4K1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
EPHA3 CRK â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11870224 16713569
CRK SRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23397142 10962563 12615911
AR SRC â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
GAB1 RET â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11360177 19914172 32062451
ERBB4 PTPN11 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ITGA4 ITGB1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
ITGAV ITGB1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
HSPB1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
GDNF RET â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
EPHB3 CRK â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9674711 16713569
CRK BCR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8943292 8978305 19380743
BRAF RAP1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26280580 16507992 10454553
SRC DOK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11071635 22974441
FGR DOK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11071635 22974441
TP53 XPO1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ERBB4 CRK â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16729043 22973453
CRK HSPB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 31980649
ASAP2 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10022920 17474147
CBLB CD2AP â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
SH2B1 NTRK1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10708759 9856458
NTF3 BDNF â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33961781 7703225
EPS15 AP2M1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24189400 33961781 26186194 19380743
AP2M1 BCR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24189400 33961781 26186194 19380743 32203420
MET CRK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24828152 24728074
RIN3 CRK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17474147 25814554 32552912
CRK SOS2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17474147 33961781 19380743
CRK CBLB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 19380743 25814554
CRK PEAK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 31980649 19380743 20534451
CRK SOCS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10022833 25814554
BCR RHOA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9535855 31871319
ANLN RHOA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31871319 25959226
SOCS1 MET â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25728680 24728074
POT1 TERF2IP â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ITGAL ITGB2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CRK SRC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
SRC RET â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 33961781 32062451 10070972
GAB1 MET â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
IGHG1 IGKC â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15174051 1522589 11183784 12552112
ELK1 MAPK3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ABL1 DOK1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PDGFRB SRC â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ITGA1 ITGB1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
ANGPT1 TEK â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
NTRK1 ABL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10708759 10679771
CBLC CRK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 10571044 25814554 10362357
GAB1 CRK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12138161 16713569 24728074 19380743
RET CRK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25241761 32062451 10208419 9393871
CRK ASAP3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 19380743 26871637
MAP2K4 MAP3K1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
YWHAB BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217174 15324660
CBLC SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20525694 14661060 22888118 9988270
CD2AP CBLB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23663663 17020880
GFRA1 GDNF â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20473317 9482105 10829012 9407096 8674117
GFRA1 RET â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 20473317 10829012 10774729 9192898
NTRK2 BDNF â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21651720 11855816 9312147
KDR SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PTPN11 SOS1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
SRC ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11494128 17474147 12522270 11781820 17318191
ABL1 BCR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12543778 1712671 8112292 21653319 11780146
FGR ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16787943 11847100 16076903
BRAF MAPK3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK3 RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK3 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
BRAF MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
MAPK3 NCF4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16778989 10400704 27558335
WDR83 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15118098 23331499
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
ARF6 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17363898 16452216 15210957
MAPK3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8197172
PRKCD NCF4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
AR PRKCD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17553165 17178875
PRKCD ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11389095 12919677
PRKCD ITGA6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11389095 12919677
PDGFRB PTPN11 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PTPN11 PDGFRB â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8119896 6730513
TP53 REV3L â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
RAP1B TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 SETD9 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15525938 16415881 21625555
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
DOK1 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19118207 12606711
ASAP2 ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10022920 10749932
DCP1A EDC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27315556 25036637 19966221 26496610 24778252 24981860 16364915 29395067 24510189
ITGAV KDR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12820653 19267251 17030947
ITGA2B CRK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
PDGFB CRK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10508235 9546424 9739761
ITGB3 CRK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
CRK RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
CRK RAP1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
EPS15 CRK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 16713569 7797522 33961781 19380743
CRK ASAP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 17474147 9819391 33961781 19380743
PDGFRB PTPN12 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 12614164 0265574 8312067
PDGFRB PIK3CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
PDGFRB SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PDGFRB PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17496910 16189514 11172806
PDGFB SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7935391 8388543 9739761
PDGFB PIK3CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
SRC KDR â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
SRC ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11723131 11259684
NGF NTRK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10713102 10490030 9857023 1849459 9083066 14985763 11738045 11729324
MAP4K5 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9712898 23331499 9405407
RHOA ERBB4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
PRKCA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11284700
NEK2 IFT140 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ASAP1 SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17474147 9819391 16636290
SRC MET â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24034250 20624308 9837958 24728074
EPHA3 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9632142
SRC PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 22402981
PRKCA ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16014375 10592173 17570479
PRKCA NCF4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
PHLPP1 PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18162466
PRKCA BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1386920 16810323 12917261
PRKCB BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1386920 17570479 12917261
PIK3CD GDNF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CD RET â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CD GFRA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CD GAB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
AR MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20610535 20946682 17283128
FER AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23906537
RPS6KB1 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19593530
PIK3CG GAB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10194437 12506011 10455108
GAB1 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10871282 8596638
PIK3CB GAB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
GAB1 PIK3R5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10194437 12506011 10455108
GDNF PIK3CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
RET PIK3CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CB SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
PIK3CB GFRA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
NTRK2 NTF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11738045 29997244 25241761 11855816
NTF4 BDNF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10631974 9519408 16189514 25241761 29997244
PTPN12 ERBB4 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 21376233 7542744 7541030
IGHG1 FCGR2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7718892 2529342 7521687
IGHG4 FCGR2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7718892 2529342 7521687
IGKC FCGR2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7718892 2529342 7521687
PRKCB NCF4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
SEMA4D MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12198496
NEK2 CNTROB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17535851 23291182
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ITGA6 ITGB1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
DOK1 RET â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
MAP2K6 MAP3K7 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
BDNF NTF3 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
NTRK3 NTF3 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 9488719 10713102 9973222 8621424
PIK3CB PIK3R3 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ANLN RHOA â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CRK EDC4 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 33961781 31980649 19380743
DOK1 RET â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 12087092 16153436
MET GAB1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10871282 10913131 10995442 10734310 9242692
NTF4 NTRK2 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
CBLC SRC â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
PTPN11 GAB1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6169284 14701753
PTPN11 GAB1 â—¼   DEPHOSPHORYLATION ✅ 0.96 0.96 mint 20308328 8288622
BDNF NTF4 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
DCP1A EDC4 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
DOK1 ABL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9008161 22974441 10688886 11071635 9822717 10567556 19823681
ABL1 CRK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 9747873 11380621 15696159 8875975 9480911 21602891 18835194 18619508 12384576 8194526 11956190 19380743 24412932 9642287 17474147 8978305 12097319 17515907 33961781 12198159 7926767
SOS1 CRK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 31980649 8810325 17474147 8943292 33961781 19380743 32203420
NGF NTRK1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
GFRA1 RET â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
GDNF GFRA1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ITGAX ITGB2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ABL1 CRK â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ITGA5 ITGB1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ITGA2B ITGB3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
GAB1 PTPN11 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 CRK â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
PTPN12 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15588985 11163214
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
NTRK1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 10708759 10679771
ABL1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 100.0 1.0 Omnipath 8978305 9747873 9480991 19426560 17081983 23124138 16522685 16713569 20841568 18768933 8875975 25860930 21779437 19534553 16187300 17515907 21602891 16267043 20068231 10592173 17570479 8194526 7926767 11080615 25381819 12198159 9642287 15696159 18619508 18835194 11956190 22848689 11314030 9480911 19001122 19402756 20697350 12384576 24412932 7542925 11380621 12799422 19380743 12955086 17474147 17016520
ABL1 BCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9407116 10405761 12522270 11780146 8622703 9178913 1712671 12124177 7529874 9467953 8955135 20841568 8112292 16912036 12543778 11376433
ABL1 PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18923184 17126298 9109492 16631755 19737086 28637715 20841568 10713049
ABL1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20841568 10866655
ABL1 MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11278340 17474147 9346925
ABL1 PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 14993293 19275932 20841568
ABL1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15039778 20841568 8112292
ABL1 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9826708 12766170 9391119 9242692 10506185 8547236 10069803 7687741 10490849 11741535 21777671 8906793 12475979 9444958 7513258 7961992 15475459 9252406 7838524 7731718 8662889 7708691
ABL1 DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11071635 10567556 12777393 9008161 15148308 15592455 25043303 18768933
HSP90AA1 GAB1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16953218 17646646 15329413 17712310 15118073
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
PRKCG HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 26804907 24117238
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
HSP90AA1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1310678 16844778 16189514 18266962
TGFBR2 MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11274345 12738796 14557817 15265520 15282297 16200688 16474430 17934056 18855897 20060931 20519943 21614932 22703233 23070005 24132110 24336330 24403530
MAP3K7 MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10391247 11280761 11460167 12620219 14633987 14660645 15082531 15125833 15282297 16200688 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20060931 20164171 21041997 21133840 21232017 22941947 24403530 24699077 24958845
MAP3K7 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 16200688 17301840 18855897 15125833 24699077 17363905 18641653 21902831 24403530 23331499 20060931 21133840 21614932 21232017 12738796 23606331 18264787 10391247 21220427 18988627 16799562 12620219 14633987 19161412 22941947 11280761 15082531 26192618 14660645 24958845 20164171 11460167 16603398 21041997 15282297 11274345
MAP3K1 MAP2K6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17143273 9639556 19369195 9712898 16728640
MAPK3 IL17RD â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
ELK1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 8386592 11145955 7588619 7889942
FGFR1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR2 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAP3K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 25241761 15315965 12049732 24135036
RET MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 551.0 1.0 Omnipath 15956760 25485910 17240116 20385359 12527803 17621270 23612968 18212246 21860413 18097051 18851832 10645003 25679764 21423210 15007380 19934253 19935718 22356909 9677429 15781651 10849428 17188005 20667468 14625304 34380633 17377139 21423211 20010870 26186445 20736304 12376318 33627405 16740736 21561860 15004239 17901130 15212956 15897464 15143154 18819921 17157789 26297582 12138104 11777927 22158866 23195225 34473994 20494825 14963038 16778204 17391526 27683117 22689060 12444552 31933886 15059947 26823016 15657432 19377875 17142325 15486045 21460222 23431142 11159838 27654866 19941816 14718389 34375550 18593598 17360704 23997214 24501773 16163708 10604992 15297577 17106060 24396487 25893857 20361349 16822962 12554776 18454177 29434871 34530870 16141331 12356731 19169277 20543098 17685427 21478906 18463290 16250012 20534535 21228323 7535768 26617336 15963258 10617652 17196532 19995915 10464310 15315965 12082540 21685939 25730857 18305109 25703330 16928771 15681433 11083859 16076871 20395206 23146907 26246800 21454539 12660819 21220474 15866871 15637081 19858202 34403210 18032526 16195541 21829454 16459330 17209045 12808105 11585739 16162500 25833830 18246127 11864968 24418169 15935618 19925796 20160123 17056593 14998784 18215133 10508618 18775330 18760948 12952943 21768338 17317777 8155326 22258404 15788397 26919095 28213521 21192818 33798093 15851026 26242183 12402043 21868357 17064352 20927383 16380505 15035987 21454675 18957207 19193766 21188622 19050043 16904111 19888469 26073130 20185553 15282551 16790523 23405013 11994288 17510392 32081857 18941537 20930115 19106095 11043579 21499301 20145126 24427291 10958690 15939799 19088846 19286657 18424438 15308678 18198175 27323814 24338688 24252946 19956644 21478903 12014987 23017243 17525129 12511559 17615152 16505244 20122898 12077249 17123942 26035354 11278407 15665049 20531297 17292825 14976148 16449644 16461767 23361053 19261611 11502744 25658205 12149254 30327409 17560175 24352879 26586479 26804906 25779944 34125833 19118012 11352917 16740725 11884401 16464862 16641227 27323830 18063582 22955283 24561529 10779765 10542198 16135812 23564461 17210721 24469048 24803537 21602434 17110601 21045017 11073973 10597231 23687376 34556812 17341659 18692468 17579083 12384403 21408150 25417160 11752053 23325789 17371847 11970985 22327338 26265441 16840783 17283152 26616862 23188829 17239630 21487005 11024037 17053147 24363437 25682201 20234004 12391272 23644655 25638159 20808799 17922836 20129247 24913355 18451171 25483104 26296889 21081844 17404396 11287604 18263590 26317416 15541367 16467309 12765939 16331263 16498402 20485667 11230338 16387841 19543320 7687743 20228268 15630487 16774943 16710359 10803464 16844778 16574647 15994317 17495961 21215800 17590453 26382850 19002495 12909616 20599567 12558965 10667594 24711455 17255109 16038803 12370087 21072043 20008839 18805968 10206983 11875080 20231899 21499296 21908610 16002410 12821943 24292678 17525735 17928416 21057531 25236495 17283137 21659545 24403530 16919488 23378338 22973961 18847491 16682955 20840866 16153436 23542175 24492000 12526087 26556867 12133965 12433918 20065107 14610044 11959800 15580310 21730285 11046056 9124279 14707024 26725216 16452220 22212957 25811962 15696170 11416124 20498373 17157787 21653826 16149052 20022946 34262144 16434970 10558990 18045996 10925301 16280323 25581518 15899879 21441955 20566643 15466476 15657177 11706017 15059847 8444886 18519681 23528009 33513601 20138986 12368275 24608435 17062641 20082306 20375017 17537990 24567333 33820494 10712263 21278199 19011679 20145145 27582276 25640183 21730054 16177091 17250586 15879307 16728403 18299328 24269888 17303383 9482941 17671177 17173941 24095720 15304500 12874275 33828192 11827968 33731431 10799542 15328343 18838481 19036157 17634226 17110082 17855349 31722981 26079947 25002506 14559232 23584478 18593910 17114467 16373398 16931794 17016429 14676826 28415597 12029087 24269383 8626767 20478260 12097262 14764579 12181310 15100319 12384432 15271996 17562849 19036927 19326083 20072652 25940440 11922392 17913704 19494114 25596730 18938240 27449290 12897059 21478911 21123455 26804170 10940302 16624816 26876209 12048182 17150968 21478863 17307705 18658095 24995980 16582879 17289590 33667549 17209041 17890097 21726627 27662093 16843264 19426503 11103941 11940578 17906618 26234813 19029090 15007386 15958730 12576312 17667937 17785202 34480897 20647329 18941890 16446383 25562429 10867021 26985018 16413470 23178720 25578563 34437586 21738699 21258408 20388777 24681954 20459645 12242309 15289328 21575862 16185843 19147767 34497368 19153083 12124352 17371994 17567959 15611080 17297454 23012246 14557270 28542650 15713673 21129803 19460345 10958798 21772273 21900206 19205871 17591920 19217381 12963813 19718025 24469056 16624867 21149447 15728578 33902596 11971971 16455819 19112174 10751321 1835084 11016927 18267069 20410276 21980390 17409387 23831578 21477078 15558056
PRKCA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK3 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 9130707 20506250 15547943 20371703 7618106 7601337 12697810 12473660 23331499 8007980 16291755 16393692 16998585 18988627 17255949 8208531 15014501 15187187 8586671 19541618 11145955 25241761 19565474 11309409 8887554 17052211 15277685 18334532 15782123 8548291 14499342 9927426 7889942 8262053 8386592 10716983 12665513 15967991 8477450 12947314 15212693 11274345
MAPK3 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 15547943 20080742 14967450 12040186 15173823 12697810 11940578 16227978 12738796 16039586 9722592 17255949 15774499 15187187 19541618 19091303 19565474 17052211 11279232 9271440 18039929 18775330 10601235 12792650 11431469
MAPK3 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 23602568 8939914 12832467 17906627
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27342992 23405013 18411303
MAPK3 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 14654779 21478863 19541618 21135229 16508002 19933846 15664191 8621729
MAPK3 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 29145629 7478566 23331499 8816480 7739560 17570479 9922370
MAPK3 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12008033 15379552
MAP2K4 PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11335711
SRC PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15851033 14970215 17569658 19366211 26876198 27203386 15961393 24211614 16982614 17570831 23329791 23329794 15541367 18550549 22689788 28637715 14715667 29422059 17658731 10319993 19138410 11927579 29452094 19632318 15337529
PRKCD TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17906639 16314418 16377624
PRKCD LIMK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15923181 16820362 22492986
PRKCD ITGB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12682249
PRKCD ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 23823319 16301335 29903913 11700305 17107954 18550856 25278023 12682249 15212693
PRKCD NCF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15035643 9804763
PRKCD MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17496910 11940581 21386996 7925482 15075332 11447289 19615955 8294430 16488589 6321473 8321321 12845332 11313945 94124523 12040186 19568798 15567848 14585353
PRKCD YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9705322 16024783 12619878
PRKCD PTPN22 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18056643
PTPN11 IL2 â—¼   DOWN_REGULATES ✅ - 26.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 17307799 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 27557510 9751747
CD3G PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
PDGFRB PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 8622870 19690332 8041791 18083107 8538796 23331499 19534553 11684012 7530043 16189514 12721296 12522270 8959326 17287340 16094384 7688466 8226787 8119896 12531430 11266449 12681492 12614164 8183548 23397142 7691811
PRKCA PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16055440 11781100
PTPN11 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 72.0 1.0 Omnipath 14701753 18577518 17145710 11453982 12582165 20308328 14665621 8596638 14982882 20473329 11027663 10592173 10788507 9658397 12024020 10068651 24728074 11134009 10194437 12855672 21442024 11323411 11940581 15574420 11278704 10871282 9804835 9632795
PTPN11 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18757826 18482983 10698938 17974954 14687660 24632723 20308328
PTPN11 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12577067 9632781 9344843
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
TP53 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22466965 18811981 16557594 24492005
TP53 PDGFRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19952113 19763735 18697203
NDN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24722188 10347180 16713569 23785149
HSPB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25241761 16169070 16713569 17184779
PRKCA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18812399 9935181 15659650 9315650 19933256 16713569 9571186 1454855
PRKCA ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11700305 12682249 17570479
ITGAV ITGB5 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGAV ITGB5 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGB5 CRK â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGB5 ITGA2 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
ITGB5 ITGA1 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 22470492 24309651 26519775 9295024 9763615
ITGAV ITGB3 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
ITGAV ITGB3 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
ITGAV CRK â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
CRK KDR â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
CRK KDR â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
CRK MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRK RAP1A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
EPHA3 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 21071413 16713569 18988627 11870224
PDGFRB CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 19426560 10733900 16713569 27686861
RET CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9393871 10208419 25241761
ARHGAP32 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12446789 12454018 12819203
CBLB CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 8626404 19380743 12697763 25814554
NTRK1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7657647 8552402 12446789 7509449
CRK GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 24728074 20619534 12138161 19380743 11146548 10592173 19350053 16713569 10618718
CRK MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 35044719 11432831 9891069 9788432 16713569 17474147 11279207
CRK MAP4K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10648385 16713569 9788432 35044719
CRK PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25814554 35044719 19380743
PDGFB PDGFRB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFB PDGFRB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 15099563 17145802 17496910 18633355 24359404
PDGFB PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9739761 20577048 30150707 16189514 15207812 28267575 7679113 11297552 15207811 20534510 17981115 10806482 285049611903042 11903042 11331882 2850496
PDGFRB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15489898 18315570 16189514 9010229 2173144
PDGFB SRC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 7685273 9488729 10508235 9739761
SRC KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19050761 18662404 18194650 10749680 12509223 18377662 10455194 16966330 12214271
ITGB1 ITGA4 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
ITGB1 ITGA5 â—¼   PHYSICAL_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
ITGB1 ITGA5 â—¼   PROTEIN_INTERACTION 29.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 12731048 15866889 16076871 16919435 17522712 18037882 19161977 19339212 19454690 19487819 20644254 20814939 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
ITGB1 ITGA4 â—¼   PROTEIN_INTERACTION 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
PRKCA ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12138200 12435334 20926684 11700305 10592173
TGFBR2 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11274345 12738796 14557817 15265520 15282297 16200688 16474430 17934056 18855897 20060931 20519943 21614932 22703233 23070005 24132110 24336330 24403530
PRKCQ MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10652356 15214048 15536066 16606694 17544292 17548359 18784374 19201850 23077238 23433459 23474202 23886063 25960930
MAP3K7 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
PRKCQ MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23433459 19201850 23109003 17544292 18784374 15536066 16606694 23886063 26192618 20164171 17548359 17363905 23077238 10652356 25960930 23474202 15214048
MAP4K1 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 10224067
RIPK2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18079694 17079228 17947236 10702308 17348859 17965022 15075345
MAP3K7 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 11477091 17301840 13130464 18855897 15125833 24699077 9278437 17363905 18641653 24403530 20060931 21133840 21614932 9891069 12738796 21232017 9851932 18264787 10391247 16799562 23109003 12620219 14633987 12709432 8177321 19161412 22941947 23681101 12556533 11280761 15082531 26192618 14660645 24958845 20164171 11460167 16603398 21041997 11274345
ITGB7 ITGAE â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10671552 11348595 11413131 15279786 16371504 17303408 17325197 17660363 17928543 17936032 18590585 19029934 19161977 22007144 22174153 22674073 7575488
ITGB7 ITGAE â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10671552 11348595 11413131 15279786 16371504 17303408 17325197 17660363 17928543 17936032 18590585 19029934 19161977 22007144 22174153 22674073 7575488
DOK1 ITGB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19118207 12606711
RAP1A POT1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
RAP1A POT1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
ITGA2B RAP1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
SRC RAP1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
ITGB3 RAP1A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
RAP1A BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12446733 9560161 9094716 11278445 16507992
NGF NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 17145710 8155326 9083066 11729324 27908981 22666365 17404842 24224055 25611061 14985763 9290260 9857023 28090201 12067229 23772401 10490030 11114882 27229480 1706478 11738045 10713102 9547236 1849459 9775403 17409494
MAP3K1 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 41.0 1.0 ACSN 10086337 10465784 10567412 10811803 10982827 11274345 11447289 11668179 11777939 12040186 12048245 12175651 12419216 12640133 12738796 12782630 14585353 15170913 15567848 15574420 15863030 16102570 16227978 16488589 16582911 16887996 17496910 17496911 17673906 18855897 19449109 19568798 19615955 21102635 21614932 24027568 26552706 7510700 8551221 9379049 9582321
MAP4K1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8824585 23331499 9003777
MAP3K1 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 83.0 1.0 Omnipath 17145710 15863030 8551221 10811803 11447289 16582911 11777939 18855897 9379049 16472679 12640133 12040186 9305638 26552706 23331499 12048245 10982827 16227978 11668179 23180781 21614932 9808624 12738796 12782630 9889102 9891069 10567412 12175651 18182252 19568798 16102570 9582321 14585353 10521444 17673906 17496910 11242034 10465784 7510700 9712898 11274345 12419216 7992057 7600582 10086337 17276500 15574420 19449109 26192618 19615955 19369195 24027568 10400627 16887996 8910292 12456688 9487126 21102635 15567848 17496911 16488589 15170913
BRAF YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12620389 17353931 24255178 15324660 10931830
ARHGAP32 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12857875 23331499 12446789 12454018
ANGPT1 TEK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 23331499 9204896 20937382 21071413 8980223 12427764 28396397 8980224 20651738 20708158 18988627 21858121 29106382 9723709
SRC RAP1B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
ITGA3 SRC â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10671552 11133108 11348595 11476890 11955436 11967263 12051714 12426320 14557817 15001769 15279786 15548370 16039586 16099633 16371504 16474430 16919435 17143292 17303408 17496910 17517963 17660363 17928543 17934056 17936032 18037882 18590585 19010789 19029934 19109155 19171760 19619488 19734908 19920116 20519943 20644162 20705860 21278795 21666923 21900405 22007144 22174153 22203675 22370635 22674073 22703233 23343194 24023259 25572304 25730849 26552706 27216177 7542250 7575488 7594497 8666229
SRC ITGA9 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11476890 16099633 16919435 17496910 17517963 19734908 22203675 22370635 25572304 26552706 27216177
AR SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19305643 10454563 18687691 17108144 17079466
PRKCB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCQ SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 17496910 11940581 21386996 10527887 2996780 11447289 19615955 16488589 6321473 8321321 12845332 11313945 2136766 17570479 12040186 19568798 15567848 14585353
PRKCE SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 11834516 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
ARHGAP32 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12454018
PTPN12 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19595712 18482983
PRKCG SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCH SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 8621384 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
SRC AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 28144231 15062576 20570899 25133482 21318111 11032808 25950519 21512132 17525795 12933816 20383201 24728074 24948875 24868554 25547388 19117998 21956655 17045208 15027889 24859991 15466214 26829214 21886458
SRC SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17474147 9856337
SRC DAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15062102 10959835 17570479 15316068 11279201
SRC GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26706435 15574420 19881549 12941962 21442024 12808090
SRC MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 24728074 24034250 9837958 17570479
SRC ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10330414 17473008 8631894 18156175 25694433 18840695 18364349 18398066 10592173 16935858 21956114 17353363 18088087 12359711 15212693 14996908 15695822 15699036 11723131 20702409
SRC RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11713247 17570479 16189514 10070972
SRC INPPL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 17389395 19901323 17081983 12522270 19534553 12235291 16497976 15592455 15951569 18083107 11349134 18669648
SRC ASAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9819391 16636290 24957964 17474147
SRC CBLC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9988270 20525694 24425877 14661060 22888118
CBLB FLT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19276253 17635922 10514377 9614102
FGFR1 SOS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
PRKCE FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 23564461 12040186 19568798 15567848 14585353
ITGB3 RAP1B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
DOK1 ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19118207 20739287 18156175 12606711
FGFR2 GAB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
FGFR2 SOS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
PRKCE FGFR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 23564461 12040186 19568798 15567848 14585353
ELK1 PRKCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26010542 16297876
PRKCA ADD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 19651622 20166139 20068231 18452278 11895774 9607561 18669648
PRKCA MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 17496910 11940581 21386996 15075332 11447289 19615955 8294430 16488589 6321473 8321321 12845332 11313945 17570479 94124523 12040186 19568798 15567848 14585353
PRKCA PTPN12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19651622 18767875 7909431 20068231 7520867 94349924 15212693 18669648
PRKCA ITGB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17615294 12919677 15121854 19005215 10592173 10477766 22824799 20870721
PHLPP1 PRKCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18162466
PRKCE MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 11447289 8321321 11313945 94124523 12040186 7925482 6321473 15567848 19568798 14585353 17496910 21386996 8294430 11940581 15075332 19615955 12845332 15212693 16488589
BRAF WDR83 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 21779496 9733512 12479806 15118098 17178906 15547943
RAP1B BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12446733 9560161 11278445
BRAF MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8385802 7731720 1748651 3043188 8073291
ITGA2B RAP1B â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
MET EPS15 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HSPB1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19767773 17974989
NTF3 NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 27908981 17439940
NTF4 NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11114882
NTRK1 ARHGAP32 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12446789 25921289
NTRK1 SH2B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10708759 23331499 29229648 9856458 15082760
RET DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19901323 23331499 10688886 16497976 15592455 16094384 12087092 11551902 16153436
ITGB4 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9428518 11733063 12867433 7721947 8143784
MET GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 10978177 17389395 19901323 10753869 15574420 15212693 10913131 10734310 11896055 20068231 10995442 9890893 16497976 14685170 17016520 18669648 11779868
GAB1 ARHGAP32 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 12819203
ITGB4 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9428518 11733063 12867433 7721947 8143784
PIK3R3 PIK3CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8596638 22402981 11733063 25814554
IGKC SOS1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
IGHM SOS1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
NTF4 NTRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11738045 767991211855816 25241761 7679912 27908981 9775403 11855816
NTF4 BDNF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25241761 7703225 29997244 16189514 10631974
RET GFRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9883723 23331499 10829012 9192898 10774729 14514671 16189514 11106404
GDNF GFRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 14514671 8674117 9482105 9182803 11106404 20473317 11544105
GDNF RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 23331499 14514671 8674117 9482105 23429478 9182803 22751117 25684228
NTF3 BDNF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 7703225
BDNF NTRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 76445409312147 7679912 21849472 27908981 9312147 23331499 9648856 11855816 26899129 7644540 1645620 26740873 9775403 21651720 28679669
BDNF NTF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 7703225
PRKCB MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
NTF3 NTRK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 1653651 23331499 10713102 7679912 27908981 9488719 9775403 9973222
PRKCG MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
NTF3 NTRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 27908981 8621424
IGHG1 CD3G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGKC CD3G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGHG4 CD3G â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGHG1 FCGR1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGKC FCGR1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478
IGHG4 FCGR1A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 8611682 7512959 7516890 8541526 8327478