Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F4 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
CHEK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218401 16511572
E2F4 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067 18319725
FANCA CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
E2F4 FOXM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
ANAPC4 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
FZR1 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
FZR1 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
FZR1 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
FZR1 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
MAPK1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
E2F4 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15510213 18319725
PLK1 SGO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18331714
STIP1 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRIM24 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0813177106 19556538
TP53 E2F4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574328 24096481
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 CDC20 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19273532 17873905
TP53 MTA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23552838 22286760
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
TP53 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19273532
E2F4 NDC80 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
NDC80 DCTN1 â—¼   COLOCALIZATION 2.0 0.8 intact 8057081 20664522
E2F4 NDC80 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18319725 16135806
E2F4 MAD2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 NEK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 BUB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15574595 18319725
E2F4 NEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18319725 16135806
CRK ASAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NEK2 CDC20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11742988 16648845
CDC20 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12196507 9628895
CDC20 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10318877 12956947
GLI1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19329935 19930158
BUB3 NEK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11742988 16648845
ANAPC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8638126 9556553
ANAPC7 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
ANAPC1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC27 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
CDC27 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC16 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC5 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC16 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC7 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
ANAPC2 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10922056 10500174
ANAPC2 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC2 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC16 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC1 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC4 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
ANAPC7 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10318877 10500174
CDC16 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC16 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10318877 10500174
TRIM27 CDC23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
ANAPC4 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
CDC23 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10500174
MAD2L1 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16439210
NEK2 MAD2L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11742988 16648845
FUNDC2 NEK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RITA1 NEK2 â—¼   COLOCALIZATION 2.0 0.8 intact 21102556 8094313
PLK1 BUB1B â—¼   PHOSPHORYLATION ✅ + 0.81 0.81 Signor 23079597
BFSP2 NEK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
GLI1 PIN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 28167297
CDC23 NEK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29863498 26496610
NEK2 APC7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23288039 29863498
NEK2 ANC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29863498 32307883
NEK2 CRCM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21900206 33961781
NEK2 DTD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NEK2 CC85A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21900206 33961781
NEK2 APC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23288039 29863498
PP1G NDC80 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CDC27 BUB3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 27114510 22193957 33961781 32152539 32076268 21926987
APC4 BUB3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27097363 24464857 23288039 24151075 23007648 21926987 23160376
CDC27 NEK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25673878 29863498 32076268 16648845
PPP1R2 PPP1CC â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8286865 10807923 003082200
PP1G NEK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21382349 24116158 23080069 24902662
APC4 NEK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29863498 23288039 25750436 25673878
TRIM27 USP7 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
ELAVL1 PRKCD â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
PCM1 PLK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 23345402 26638075
STK3 PLK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20562859 24255178 27566175
BUB1B FZR1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MTA1 TP53 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ANAPC2 BUB1B â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ANAPC5 NEK2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ANAPC2 NEK2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CDC26 MAD2L1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ANAPC7 MAD2L1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
TP53 PIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 12397362 5215850
NEK2 PP1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10880350 22321011 12221103
CDC20 FZR1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
BUB1B PLK1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17376779 19503101 28410192 26323689 23455478 24067371
PLK1 DCTN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 12852857
PSMA6 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
TANK PLK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20484576 33961781 21988832
CDC26 CDC20 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26811472 23443559 20360068 25306918 25723520
CDC23 BUB3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 20360068
MAD2L1 BUB1B â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 21772247 8284719
CDC16 NEK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29863498 26496610 20360068
APC1 CDC26 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 33961781 26344197 20360068
CDC23 CDC26 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 26496610 20360068
CDC26 APC7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 26344197 20360068
NEK2 CP250 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9647649 23443559
FZR1 PLK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ANAPC4 BUB3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CHEK1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MAPK1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PIN1 CDC27 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 16713569 10939594 9499405 10037602
CDC20 APC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18997788 27114510 25482201 26811472 24464857 33310066 20360068 25306918 28404789 11438673 26960431
CDC20 BUB3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 23643811 25482201 27114510 23443559 24464857 26811472 25306918 29973720 21407176 25833949 28410192 33961781 21926987
CDC23 BUB1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20360068 28404789 26496610 33961781 32707033
ANC2 BUB1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22193957 33961781 25852190 34079125 32707033
APC1 BUB1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25852190 32707033 25482201 20360068
CDC26 APC4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20360068 25043029 25490258 26083744 25723520 29549242 33961781 23078409 26344197
BUB3 CDC23 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ANAPC15 CDC20 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ANAPC15 FZR1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
ANAPC2 MAD2L1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
BUB3 MAD2L1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PLK1 PIN1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 16118204 9499405 10037602
PCM1 NDC80 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27107012 34079125 26638075
CDC20 CDC23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18997788 27114510 26811472 23443559 24464857 20360068 25306918 26496610 28404789
APC7 BUB1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10477750 20360068 23288039 26986935 28404789 32707033 23160376
CDC16 BUB1B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10477750 20360068 24151075 11030144 33961781 32707033
BUB1B APC4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25669885 25673878 27097363 24464857 23160376 20360068 27939943 25383541 23288039 24151075 31911655 26986935 28404789 25750436 33961781 23007648 21926987 21336306
PPP1R13L PPP1CA â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 21998301 270751 8217559
APC7 CDC27 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21241890 22193957 17942546 21043528 27114510 26811472 25306918 12956947 32076268 20686030 22939629 10922056 23160376 25490258 16364912 28404789 27173435 32152539 14657031 26344197
CDC26 CDC27 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20360068 12956947 16364912 25723520 33961781 32152539 32076268 14657031 10922056 21043528
APC4 CDC27 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24464857 20360068 23007648 18471975 25383541 21241890 26496610 22193957 25750436 23078409 21926987 21043528 27114510 25673878 26811472 12956947 26083744 25723520 32076268 20686030 22939629 10922056 21336306 25043029 25490258 16364912 26960431 21335556 29549242 32152539 14657031 26344197 23007861
APC7 CDC16 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 20360068 26496610 33961781 27173435 10318877 22939629
APC1 CDC16 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 20360068 26496610 33961781 22939629 11076961 26344197
APC1 CDC23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 11076961 26496610 20360068
CDC23 APC7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26344197 27173435 26496610 20360068
ANAPC15 NEK2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
PPP1CA PPP1R13L â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PSMC3 UBB â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
ANAPC1 NEK2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ANAPC7 NEK2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
TP53 BCL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12808109 24189068
FOXM1 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19276163 20379221 23037713
ANAPC2 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9811605 10500174
FZR1 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9811605 10500174
PDE4DIP IMMT â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IMMT NEK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
PRKCD PIN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
PRKCD CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 25639486
TP53 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15469934 14586398
NEK2 NDC80 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21900206 9295362 12386167
ANC2 CDC20 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27114510 26811472 23443559 16287863 20360068 26387737 25306918 9811605 32307883 22193957 11438673 32905768 21937719 27120157
APC7 CDC20 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18997788 27114510 26811472 23443559 24464857 20360068 25306918 12956947 28404789 26960431 19826003 10318877 23160376
CDC20 CDC16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18997788 27114510 24100295 26811472 23443559 24464857 20360068 25306918 12956947 26496610 12196507 9628895 23007648
CDC20 APC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24464857 20360068 23007648 18471975 27097363 25383541 26986935 25750436 23078409 21926987 27114510 25673878 26811472 25306918 23288039 23160376 21336306 23443559 27939943 25043029 24151075 28404789 21335556 32152539
CDC20 CDC27 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 24100295 20081372 24464857 20360068 16479161 24781523 25246557 17443180 18471975 18997788 18059335 23239745 23643811 25161877 20054826 14561775 22193957 25750436 20212161 21926987 22280307 21937719 19098431 25673878 26811472 27114510 29700288 25306918 12956947 9811605 23754430 18794143 9628895 17443186 32076268 21525009 22100920 23160376 24811168 20951947 9637688 23443559 9736712 22014574 9734353 18722180 30341343 25156254 17609108 28404789 29432156 26960431 21335556 12196507 32152539 23979597 21454660 17360335 23007861
CDC20 BUB1B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25241761 25482201 24464857 20360068 22566641 25246557 11702782 23007648 25852190 26912231 11274370 25505175 23239745 18997788 23643811 19820702 25383541 33310066 22000412 26986935 11030144 22193957 29973720 27694884 25750436 25012665 24581499 23791783 21926987 20212161 21937719 18591651 20512932 23091007 17598981 19098431 25669885 25673878 27114510 26811472 28096334 25306918 21407176 19407811 32707033 23345399 11535616 22100920 20733051 23443559 27939943 24151075 30341343 28404789 29432156 26960431 11907259 21335556 12196507 25833949 25502805 32152539 33961781 17360335 21300909
NEK2 IFT140 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GIT1 NEK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SAV1 STK3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32707033 32296183 21988832 15688006 20920251 20562859 16930133 33961781 24255178 26186194 24981860 17379520 23455922 24366813
BUB1B CDC27 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 20360068 25246557 21300909 25852190 10477750 22193957 11030144 25012665 20212161 21926987 27114510 25673878 26811472 25306918 23754430 32076268 21525009 32707033 22100920 20951947 18722180 30341343 29432156 33961781 32152539 23007861
DCTN1 NEK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NEK2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18086858
PPP1R2 PPP1CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8286865 003082200 10807923
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PPP1CA NEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17283141 10880350 12221103
MAD2L1 CDC27 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 21772247 8284719
ANC2 CDC27 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20360068 21768287 22193957 22280307 21043528 27120157 27114510 26811472 16648845 25306918 12956947 26083744 17443186 32076268 22939629 10922056 25043029 16364912 32152539 14657031
CDC16 CDC27 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24100295 20360068 17187060 21186364 26496610 22193957 9356466 20733055 21043528 27114510 7736578 16648845 25306918 12956947 9628895 32076268 22939629 10922056 16364912 33961781 27173435 32152539 9405394 14657031 26344197
CDC27 APC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27114510 20360068 12956947 16364912 22193957 17942546 32152539 32076268 20686030 22939629 11076961 21043528 26344197
CDC27 CDC23 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20360068 22792066 26496610 22193957 17942546 22280307 21043528 27114510 16648845 32934012 12956947 32076268 20686030 22939629 10922056 16364912 27173435 32152539 14657031 26344197
CDC23 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 10500174
ANAPC4 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25383541 10500174
ANAPC5 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10500174
MAD2L1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9736712 20212161 16189514
CDC27 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25383541 10500174
CDC27 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10500174
CDC27 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 10500174
APC4 CDC16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25673878 20360068 12956947 25043029 25490258 26496610 26083744 25723520 21335556 33961781 29549242 23078409 21926987 22939629 26344197
CDC16 CDC26 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 25416956 21988832 20360068 26496610 25723520 19668213 33961781 21516116 26344197
CDC16 ANC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 27120157 22939629 20360068 12956947 25043029 26496610 26083744 33961781 34079125 10922056 26344197
CDC23 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10318877 10500174
CDC16 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10318877 10500174
ANC2 CDC26 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20360068 12956947 25043029 26083744 33961781 10922056 27120157
APC4 CDC23 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20360068 12956947 25043029 25490258 26496610 26083744 29549242 23078409 22939629 26344197
CDC23 ANC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22939629 20360068 12956947 25043029 26496610 26083744 34079125 10922056 27120157
EIF4A2 NEK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PP1G PP1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 26496610 33961781 27173435 26186194 30344098 24366813 28330616 26344197
APC1 APC7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20360068 12956947 22939629 11076961 26344197
APC4 APC7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12956947 23288039 25043029 25490258 26986935 26083744 28404789 29549242 23078409 21926987 22939629 26344197
APC7 ANC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22939629 25043029 12956947 26083744 10922056 27120157
EDRF1 NEK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TPM3 NEK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TCF25 NEK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MCC NEK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NEK2 PDE4DIP â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NEK2 SPTBN4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NEK2 CNTROB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17535851 23291182
ANC2 APC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25673878 27120157 22939629 12956947 25043029 25490258 26083744 29549242 34079125 23078409 10922056 26344197
APC1 ANC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22939629 20360068 12956947 25043029 26083744 34079125 10922056 11076961 27120157
APC1 APC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24464857 20360068 12956947 25043029 25490258 26083744 29549242 23078409 22939629 11076961 26344197
MAPK1 RPS6KA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
E2F4 PIN1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
ANAPC1 MAD2L1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
BUB3 CDC20 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
BUB1B PLK1 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
ANAPC15 CDC27 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CDC27 NEK2 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ANAPC1 ANAPC15 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ANAPC15 CDC16 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ANAPC15 CDC26 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ANAPC15 CDC23 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ANAPC15 ANAPC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ANAPC15 ANAPC7 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CDC23 NEK2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
UBB USP7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
PPP1CA PPP1R2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
STK3 SAV1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
BUB1B CDC26 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
CDC26 NEK2 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
PPP1CC PPP1R2 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
ANAPC5 CDC26 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
PARK2 UBB â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
ANAPC5 BUB1B â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CDC23 MAD2L1 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
ANAPC4 NEK2 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
CDC20 BUB1B â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 37926298
BUB3 BUB1B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 25416956 25482201 21988832 25246557 11702782 25852190 25505175 25383541 22000412 26496610 22193957 29973720 25012665 28410192 23791783 21937719 25669885 9660858 12419313 19407811 32707033 11535616 22100920 27939943 24151075 28404789 25833949 32152539 26186194 33961781 20220147
PPP1R13L TP53 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ANAPC7 BUB1B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ANAPC1 CDC26 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CDC16 NEK2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ANAPC7 CDC26 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ANAPC15 ANAPC4 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CDC20 CDC26 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CDC23 CDC26 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ANAPC5 ANAPC7 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ANAPC5 CDC20 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
BUB1B CDC23 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ANAPC15 ANAPC2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MAD2L1 CDC20 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 21772247 8284719
CDC16 CDC23 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 20360068 26496610 33961781 27173435 10318877 22939629 26344197
BUB1B BUB3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
SAV1 STK3 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC5 CDC23 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC1 ANAPC7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC4 CDC26 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ANAPC7 CDC23 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BUB1B CDC16 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ANAPC7 CDC16 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CDC27 MAD2L1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ANAPC4 CDC20 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CDC16 CDC26 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ANAPC1 BUB1B â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ANAPC5 CDC16 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
ANAPC2 CDC20 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
BUB1B CDC27 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
ANAPC1 CDC20 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDC20 CDC23 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC16 MAD2L1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ANAPC4 BUB1B â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMA6 PSMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
BUB1B MAD2L1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ANAPC1 CDC23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ANAPC1 CDC16 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC16 CDC23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ANAPC4 MAD2L1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC16 CDC20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
ANAPC4 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDC26 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC7 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC5 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC7 CDC20 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDC23 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC5 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDC26 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDC16 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC7 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 ANAPC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 CDC16 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 CDC26 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC2 ANAPC7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC1 ANAPC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 CDC16 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC4 ANAPC7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CHEK1 FANCA â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17582221 18677104 18931676 19686080 19793801
TP53 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21546904 11158294 20190799 19435816 18632613 15016801 19395378 11152453 18753293
CHEK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 20950777 18778462 25545885 18677104 20860841 15798197 19793801 22891162 16511572 23852422 16713569 15865930 11551930 19923893 15467443 11709713 21748595 17116885 15659650 17582221 26384650 10673501 17384638 23966620 23892398 17118344 9765199 15140942 19788416 10801407 18319725 12781359 12897801 25823026 15459660 23296650 15024084 17296725 17102137 11896572 17339337 19933256 20526329 28140789
CHEK1 FANCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17296725 19686080 18677104 15798197 17102137 17116885 17582221 19793801 17384638 18931676 15459660
CHEK1 NEK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20090422 19734889 22655267
PRKCD ELAVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18285462 20798862 34406862 23921630 19528229 23115237 20086103 28383062 17392515 23978401 24492650
ELAVL1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18680106 12963828 18519672
FOXM1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15817462 16314512 16809346 17173139 15531365 15654331 15689977
CDC23 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDC16 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDC27 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ANAPC1 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDC27 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12797865 12956947 23029392 18662541 9637688 15916961 22014574 21241890 10500174 26963853
FZR1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12797865 12956947 23029392 18662541 9637688 15916961 22014574 21241890 10500174 26963853
ETS1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 8552081 10358095 20534573 11782450 15572696
MAPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8939914 12832467 9915826 17906627 32296183 19282669
MAPK1 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21494553 21449613 25241761 16045329 23991633 20361728 11570862 22521293 11948414
MAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 14965474 9765199 15116093 21675959 23443559 10781582 25241761 10446957 10958792 11409876 11709713 21147777 10673501 11551930 15867353 11875057 12091386
NEK2 NEK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15161910 17145710
PLK1 CDC20 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
E2F4 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17531812 15105433 17981789
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 PIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 27618008 23633483 16118204 9499405 16713569 25070718 25766872 10037602 22926167
PLK1 DCTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21931181 28415805 23985322 23661607 20679239
PLK1 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19686080 19270156 18931676 19622404
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
PLK1 ANAPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18931676 16565220 19270156 19622404 27120157 19686080 14657031 15302935
PLK1 ANAPC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 19622404 19686080 14657031
PLK1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18931676 16565220 19270156 19622404 19686080 14657031
PLK1 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18931676 19270156 19622404 19686080 14657031
PLK1 CDC23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 19622404 19686080 14657031
PLK1 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19686080 19270156 18931676 19622404
PLK1 BUB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23695676 19228686 17376779 27568981 23079597 26259146 27308323 17785528 19015317 22566210
PLK1 CDC26 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19686080 19270156 18931676 19622404
PLK1 ANAPC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19686080 19270156 18931676 19622404
PRKCD TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17906639 16314418 16377624
ETS1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12145208 19022222 8649821 10510472
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
PPP1R13L TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17906639 21192816 18275817 16713569 15558054 12524540 23623661
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PIN1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12397362 12388558 17906639 12397361 21741598 16713569 24982848 21900206
PPP1CC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17274640 15178317 16501611
TP53 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18172499 18695251 24667498 22056774 17290220 17592138 12421820 18413597 20173098 19556538 21857681 17470788 18359851 19805293 19196987 12640129
PIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 11533658
NEK2 NDC80 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 26595804 22655255 12386167 19228686 18297113 27764815 9295362 21832156 24662830 21900206
E2F4 ANAPC15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 11799066
BUB1B CDC20 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDC20 BUB3 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10477750 11402067 11535616 12640463 15024386 15279786 15592459 17303408 17376779 17498870 17660363 18022367 18590585 19154723 19182530 19503101 21270334 23197039 7575488 8824189 9790499
CDC20 CDC27 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDC20 MAD2L1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDC20 BUB3 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10477750 11402067 11535616 12640463 15024386 15279786 15592459 17303408 17376779 17498870 17660363 18022367 18590585 19154723 19182530 19503101 21270334 23197039 7575488 8824189 9790499
CDC27 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 25156254 12956947 9736712 17443186 22014574 9637688 24781523 16189514 14561775 12196507
BUB1B CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 63.0 1.0 Omnipath 11535616 23443559 11030144 25383541 19098431 23239745 18997788 22000412 15525512 25750436 12196507 16647857 23791783 25482201 25505175 25502805 22100920 25246557 20512932 11907259 25852190 21937719 11702782 20733051 25669885 25306918 19820702 22566641 26811472 25241761 25833949 25012665 27114510 24464857 21407176 17598981 23643811 19407811 23091007 17360335 11274370 18591651 24581499 20360068 26986935 31515488 25673878 21926987 24151075
MAD2L1 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 89.0 1.0 Omnipath 23443559 20212161 20081372 16525508 9637688 25383541 19098431 23239745 18997788 19143472 21335556 25750436 12196507 15182668 19826003 21743465 16647857 23791783 9736712 25482201 21772247 22100920 20512932 11804586 26496610 16189514 14561775 25092294 11702782 25669885 14607335 25306918 26811472 11438673 21525009 25012665 17443186 21041666 11707408 23754430 18794143 21407176 22340593 24464857 9628895 23643811 17360335 11274370 15694304 24581499 20360068 18592005 26986935 21300909 16497171 10700282 18318601 20054826 25673878 18022367 17443180 21926987 24151075
CDC20 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 25156254 12956947 9736712 17443186 22014574 9637688 24781523 16189514 14561775 12196507
GLI2 GLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16571352 15175043 12165851 9636069
GLI2 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18813803 16880536 19190345 18698484 15087129 17845852 19049965 11001584 20107231 20712011 15520176 16406505 17000779 16413481 16571352 16396903 9609833 18497536 14555646 9216996 20581804 11493558 15140221 16054035 20143239
SAV1 STK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20562859 21988832 17379520 24366813 16930133 26186194 17145710 24255178 20920251 21084559 15688006 32296183 29063833 23455922
STK3 NEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17197699 21076410
PPP1R2 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 22321011 26186194 28330616 20826336 27173435 18250156 10807923
ANAPC2 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 10922056 10500174
CDC16 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 9405394 17187060 24100295 7736578 21043528 10922056 26496610 9356466 25306918 12956947 20733055 22193957 27114510 16648845 9628895 14657031 20360068 16364912 10500174
CDC27 ANAPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 10922056 10500174
CDC27 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 9405394 17187060 24100295 7736578 21043528 10922056 26496610 9356466 25306918 12956947 20733055 22193957 27114510 16648845 9628895 14657031 20360068 16364912 10500174
NEK2 PPP1CC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21382349 23080069 24902662 10880350
ANAPC2 CDC23 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDC26 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21988832 20360068 25416956 25723520 31515488 26496610 32296183 19668213
CDC16 CDC26 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21988832 20360068 25416956 25723520 31515488 26496610 32296183 19668213
ANAPC4 CDC23 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
NEK2 CEP250 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9647649 23443559 25660448 24695856 32606248 21076410 12140259
NEK2 SGO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22201785 18669648 17621308